1O49A

Crystal structure of sh2 in complex with ru85493.
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 24
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o49A00
1A09A 1LUKA 3PJPA 1UUSA 1TZEE 1O4PA 1SHDA 2PNBA 1AYCA 1O46A 4JGHA 1A1EA 1LUNA 3S8OA 1LUIA 1ZFPE 2ETZA 1O4AA 1AB2A 2CRHA 3HCKA 2AOAA 1NZLA 4H1OA 5AULA 4U17A 5I6VA 1O4JA 1BKMA 4GL9E 1SPSA 1R1PA 3OVEA 1O4CA 5KAZA 4E93A 1G83A 1QG1E 1KA6A 1A08A 3VRQA 3PS5A 3CD3A 1R1QA 1NRVA 1SHAA 2L4KA 3VS2A 3VS4A 3VRZA 1FMKA 1FHSA 3BUNB 1LKKA 2PTKA 4P9VA 2L3TA 3QWXX 2K7AB 3PLFB 3UF4A 3T04A 1BFIA 1BG1A 1CWEA 3TL0A 2Y3AB 1D4WA 2Y1MA 4L1BB 4GPLB 2OZOA 5HKYA 2MRJA 3VS6A 1NZVA 1MILA 2CI9A 2MQIA 4OHDA 1AOTF 3GQIB 4JE4A 3PSJA 1OO3A 5BO4A 4EY0A 3CBLA 1BLKA 2B3OA 3PQZA 2RORA 2DVJA 2C9WA 5AXIA 5HKZA 3US4A 5EELA 2CIAA 3BUOB 3N7YA 5EHRA 1LCJA 3ZNIA 2CBLA 1O41A 1WQUA 4K45A 1RPYA 5J3XA 1FU6A 4XZ1A 2SHPA 4F5AA 1O4NA 3IN7A 3K2MA 1K9AA 4OHLA 1BLJA 4OHEA 1FU5A 2ECDA 1O48A 1BM2A 2IUIA 2HDVA 4NWGA 1M61A 1F1WA 2DM0A 4DGPA 1O4OA 1OPLA 4LUEA 2CR4A 4QSYA 1O4MA 1Y57A 4K2RA 1UURA 2C0IA 2EKXA 1HCTB 2CI8A 1BHHA 2DX0A 1F2FA 4GWFA 1QADA 2LQWA 3M7FA 1SKJA 1TCEA 2DLYA 1O4GA 3S8NA 1O4LA 1YVHA 3N84A 1KC2A 3OB2B 1JYUA 1AYBA 1IJRA 1O4FA 3VRNA 1R1SA 1X27A 1BFJA 2CS0A 2Y1NA 5EG3B 4A4CA 3EAZA 1O4EA 1JWOA 3VS7A 3VGOA 4JEGA 3UYOA 3GXXA 5GJHA 1GHUA 1LCKA 3IN8A 3MXYA 4F59A 2EO3A 3VS1A 3TKZA 4A4BA 2LNWA 1GRIA 1BF5A 3VS3A 3CWGA 3OV1A 3PFVA 3VS0A 2HCKA 2EU0A 1CSZA 4K44A 2K79B 2HUWA 1O4QA 1A81A 1X6CA 2HMHA 2C0OA 3BUWB 1O42A 3WA4A 5EHPA 3IMJA 4OHIA 5HKWA 1AOUF 3S8LA 2RSYA 3VRYA 1X0NA 1XA6A 2MRKA 4ROJA 5GJIA 3PSKA 2EOBA 1D4TA 1A1BA 4XZ0A 4FL2A 1O45A 1YVLA 1BKLA 1O4RA 5D0JA 3VS5A 1O47A 4LUDA 1FBZA 2SRCA 1FYRA 2DLZA 1LUMA 4H34A 3HHMB 1CJ1A 5DC0B 4M4ZA 1BMBA 1FBVA 2IZVA 2AUGA 1O49A 2YSXA 1M27A 1P13A 4U1PA 2L6KA 1BHFA 1A1AA 2LNXA 2H46E 2PLEA 5IBSA 1H9OA 4K11A 1QCFA 2PNAA 1O4BA 1D1ZA 1AYAA 1O44A 3S9KA 2PLDA 2MK2A 1Y1UA 1O4DA 4OHHA 2MC1A 3CXLA 2EYZA 3MAZA 3N8MA 4FL3A 3MXCA 1RJAA 5EEQA 1OO4A 1B47A 1SPRA 3OP0A 5DC9A 5DC4A 2AOBA 2C0TA 2OQ1A 1JYQA 3OB1B 3QWYA 2LQNA 1RQQC 3KFJA 2RVFA 3BUMB 2H5KA 1O4KA 1KA7A 2RMXA 2FCIA 4D8KA 1A1CA 1AYDA 2XP1A 2H8HA 1IS0A 1O4HA 3BUXB 2YU7A 3VROA 1CSYA 2EYVA 1BHHB 1Z3KA 2BBUA 5DF6A 1OPKA 1O43A 5CDWA 2ABLA 4EIHA 2EO6A 4DGXA 3VRRA 4F5BA 1PICA 2JYQA 2EYYA 2VIFA 4NWFA 2KNOA 3IMDA 4WWQA 1I3ZA 1HCSB 3GXWA 4E68A 3NHNA 1AD5A 2GSBA 1A07A 1KSWA 2DCRA 4TZIA 1SHBA 2FO0A 2KK6A 1CWDL 1JU5A 2QMSA 3HIZB 2EL8A 4P9ZA 4X6SA 3EACA 1LKLA 2GE9A 2LCTA 1MW4A 1O4IA 3BKBA 3C7IA 5IBMA 2IUGA 4FBNA 3VRPA 2HDXA 2IUHA 1JYRA
chains in the Genus database with same CATH superfamily
1A09A 1LUKA 3PJPA 1UUSA 1TZEE 1O4PA 1SHDA 2PNBA 1AYCA 1O46A 4JGHA 1A1EA 1LUNA 3S8OA 1LUIA 1ZFPE 2ETZA 1O4AA 1AB2A 2CRHA 3HCKA 2AOAA 1NZLA 4H1OA 5AULA 4U17A 5I6VA 1O4JA 1BKMA 4GL9E 1SPSA 1R1PA 3OVEA 1O4CA 5KAZA 4E93A 1G83A 1QG1E 1KA6A 1A08A 3VRQA 3PS5A 3CD3A 1R1QA 1NRVA 2KGYA 1SHAA 2L4KA 3VS2A 3VS4A 3VRZA 1FMKA 1FHSA 3BUNB 1LKKA 2PTKA 4P9VA 2L3TA 3QWXX 2K7AB 3PLFB 3UF4A 3T04A 1BFIA 1BG1A 2LRAA 1CWEA 3TL0A 2Y3AB 1D4WA 2Y1MA 4L1BB 4GPLB 2OZOA 5HKYA 2MRJA 3VS6A 1NZVA 1MILA 2CI9A 2MQIA 4OHDA 1AOTF 3GQIB 4JE4A 3PSJA 1OO3A 5BO4A 4EY0A 3CBLA 1BLKA 2B3OA 3PQZA 2RORA 2DVJA 2C9WA 5AXIA 5HKZA 3US4A 5EELA 2CIAA 3BUOB 3N7YA 5EHRA 1LCJA 3ZNIA 2CBLA 1O41A 1WQUA 4K45A 1RPYA 5J3XA 1FU6A 4XZ1A 2SHPA 4F5AA 1O4NA 3IN7A 3K2MA 1K9AA 4OHLA 1BLJA 4OHEA 1FU5A 2ECDA 1O48A 1BM2A 2IUIA 2HDVA 4NWGA 1M61A 1F1WA 2DM0A 4DGPA 1O4OA 1OPLA 4LUEA 2CR4A 4QSYA 1O4MA 1Y57A 4K2RA 1UURA 2C0IA 2EKXA 1HCTB 2CI8A 1BHHA 2DX0A 1F2FA 4GWFA 1QADA 2LQWA 3M7FA 1SKJA 1TCEA 2DLYA 1O4GA 3S8NA 1O4LA 1YVHA 3N84A 1KC2A 3OB2B 1JYUA 1AYBA 1IJRA 1O4FA 3VRNA 1R1SA 1X27A 1BFJA 2CS0A 3LYVA 2Y1NA 5EG3B 4A4CA 3EAZA 1O4EA 1JWOA 3VS7A 3VGOA 4JEGA 3UYOA 3GXXA 5GJHA 1GHUA 1LCKA 3IN8A 3MXYA 4F59A 2EO3A 3VS1A 3TKZA 4A4BA 2LNWA 1GRIA 1BF5A 3VS3A 3CWGA 3OV1A 3PFVA 3VS0A 2HCKA 2EU0A 1CSZA 4K44A 2K79B 2HUWA 1O4QA 1A81A 1X6CA 2HMHA 2C0OA 3BUWB 3K2TA 1O42A 3WA4A 5EHPA 3IMJA 4OHIA 5HKWA 1AOUF 3S8LA 2RSYA 3VRYA 1X0NA 1XA6A 2MRKA 4ROJA 5GJIA 3PSKA 2EOBA 1D4TA 1A1BA 4XZ0A 4FL2A 1O45A 1YVLA 1BKLA 1O4RA 5D0JA 3VS5A 1O47A 4LUDA 1FBZA 2SRCA 1FYRA 2DLZA 1LUMA 4H34A 3HHMB 1CJ1A 5DC0B 4M4ZA 1BMBA 1FBVA 2IZVA 2AUGA 1O49A 2YSXA 1M27A 1P13A 4U1PA 2L6KA 1BHFA 1A1AA 2LNXA 2H46E 2PLEA 5IBSA 1H9OA 4K11A 1QCFA 2PNAA 1O4BA 1D1ZA 1AYAA 1O44A 3S9KA 2PLDA 2MK2A 1Y1UA 1O4DA 4OHHA 2MC1A 3CXLA 2EYZA 3MAZA 3N8MA 4FL3A 3MXCA 1RJAA 5EEQA 1OO4A 1B47A 1SPRA 3OP0A 5DC9A 5DC4A 2AOBA 2C0TA 2OQ1A 1JYQA 3OB1B 3QWYA 2LQNA 1RQQC 3KFJA 2RVFA 3BUMB 2H5KA 1O4KA 1KA7A 2RMXA 2FCIA 4D8KA 1A1CA 1AYDA 2XP1A 2H8HA 1IS0A 1O4HA 3BUXB 2YU7A 3VROA 1CSYA 2EYVA 1BHHB 1Z3KA 2BBUA 5DF6A 1OPKA 1O43A 5CDWA 2ABLA 4EIHA 2EO6A 4DGXA 3VRRA 4F5BA 1PICA 2JYQA 2EYYA 2VIFA 4NWFA 2KNOA 3IMDA 4WWQA 1I3ZA 1HCSB 3GXWA 4E68A 3NHNA 1AD5A 2GSBA 1A07A 1KSWA 2DCRA 4TZIA 1SHBA 2FO0A 2KK6A 1CWDL 1JU5A 2QMSA 3HIZB 2EL8A 4P9ZA 4X6SA 3EACA 1LKLA 2GE9A 2LCTA 1MW4A 1O4IA 3BKBA 3C7IA 5IBMA 2IUGA 4FBNA 3VRPA 2HDXA 2IUHA 1JYRA
chains in the Genus database with same CATH topology
1A09A 1LUKA 3PJPA 1UUSA 1TZEE 1O4PA 1SHDA 2PNBA 1AYCA 1O46A 4JGHA 1A1EA 1LUNA 3S8OA 1LUIA 1ZFPE 2ETZA 1O4AA 1AB2A 2CRHA 3HCKA 2AOAA 1NZLA 4H1OA 5AULA 4U17A 5I6VA 1O4JA 1BKMA 4GL9E 1SPSA 1R1PA 3OVEA 1O4CA 5KAZA 4E93A 1G83A 1QG1E 1KA6A 1A08A 3VRQA 3PS5A 3CD3A 1R1QA 1NRVA 1SHAA 2L4KA 3VS2A 3VS4A 3VRZA 1FMKA 1FHSA 3BUNB 1LKKA 2PTKA 4P9VA 2L3TA 3QWXX 2K7AB 3PLFB 3UF4A 3T04A 1BFIA 1BG1A 1CWEA 3TL0A 2Y3AB 1D4WA 2Y1MA 4L1BB 4GPLB 2OZOA 5HKYA 2MRJA 3VS6A 1NZVA 1MILA 2CI9A 2MQIA 4OHDA 1AOTF 3GQIB 4JE4A 3PSJA 1OO3A 5BO4A 4EY0A 3CBLA 1BLKA 2B3OA 3PQZA 2RORA 2DVJA 2C9WA 5AXIA 5HKZA 3US4A 5EELA 2CIAA 3BUOB 3N7YA 5EHRA 1LCJA 3ZNIA 2CBLA 1O41A 1WQUA 4K45A 1RPYA 5J3XA 1FU6A 4XZ1A 2SHPA 4F5AA 1O4NA 3IN7A 3K2MA 1K9AA 4OHLA 1BLJA 4OHEA 1FU5A 2ECDA 1O48A 1BM2A 2IUIA 2HDVA 4NWGA 1M61A 1F1WA 2DM0A 4DGPA 1O4OA 1OPLA 4LUEA 2CR4A 4QSYA 1O4MA 1Y57A 4K2RA 1UURA 2C0IA 2EKXA 1HCTB 2CI8A 1BHHA 2DX0A 1F2FA 4GWFA 1QADA 2LQWA 3M7FA 1SKJA 1TCEA 2DLYA 1O4GA 3S8NA 1O4LA 1YVHA 3N84A 1KC2A 3OB2B 1JYUA 1AYBA 1IJRA 1O4FA 3VRNA 1R1SA 1X27A 1BFJA 2CS0A 2Y1NA 5EG3B 4A4CA 3EAZA 1O4EA 1JWOA 3VS7A 3VGOA 4JEGA 3UYOA 3GXXA 5GJHA 1GHUA 1LCKA 3IN8A 3MXYA 4F59A 2EO3A 3VS1A 3TKZA 4A4BA 2LNWA 1GRIA 1BF5A 3VS3A 3CWGA 3OV1A 3PFVA 3VS0A 2HCKA 2EU0A 1CSZA 4K44A 2K79B 2HUWA 1O4QA 1A81A 1X6CA 2HMHA 2C0OA 3BUWB 1O42A 3WA4A 5EHPA 3IMJA 4OHIA 5HKWA 1AOUF 3S8LA 2RSYA 3VRYA 1X0NA 1XA6A 2MRKA 4ROJA 5GJIA 3PSKA 2EOBA 1D4TA 1A1BA 4XZ0A 4FL2A 1O45A 1YVLA 1BKLA 1O4RA 5D0JA 3VS5A 1O47A 4LUDA 1FBZA 2SRCA 1FYRA 2DLZA 1LUMA 4H34A 3HHMB 1CJ1A 5DC0B 4M4ZA 1BMBA 1FBVA 2IZVA 2AUGA 1O49A 2YSXA 1M27A 1P13A 4U1PA 2L6KA 1BHFA 1A1AA 2LNXA 2H46E 2PLEA 5IBSA 1H9OA 4K11A 1QCFA 2PNAA 1O4BA 1D1ZA 1AYAA 1O44A 3S9KA 2PLDA 2MK2A 1Y1UA 1O4DA 4OHHA 2MC1A 3CXLA 2EYZA 3MAZA 3N8MA 4FL3A 3MXCA 1RJAA 5EEQA 1OO4A 1B47A 1SPRA 3OP0A 5DC9A 5DC4A 2AOBA 2C0TA 2OQ1A 1JYQA 3OB1B 3QWYA 2LQNA 1RQQC 3KFJA 2RVFA 3BUMB 2H5KA 1O4KA 1KA7A 2RMXA 2FCIA 4D8KA 1A1CA 1AYDA 2XP1A 2H8HA 1IS0A 1O4HA 3BUXB 2YU7A 3VROA 1CSYA 2EYVA 1BHHB 1Z3KA 2BBUA 5DF6A 1OPKA 1O43A 5CDWA 2ABLA 4EIHA 2EO6A 4DGXA 3VRRA 4F5BA 1PICA 2JYQA 2EYYA 2VIFA 4NWFA 2KNOA 3IMDA 4WWQA 1I3ZA 1HCSB 3GXWA 4E68A 3NHNA 1AD5A 2GSBA 1A07A 1KSWA 2DCRA 4TZIA 1SHBA 2FO0A 2KK6A 1CWDL 1JU5A 2QMSA 3HIZB 2EL8A 4P9ZA 4X6SA 3EACA 1LKLA 2GE9A 2LCTA 1MW4A 1O4IA 3BKBA 3C7IA 5IBMA 2IUGA 4FBNA 3VRPA 2HDXA 2IUHA 1JYRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A09 A;  1LUK A;  3PJP A;  1UUS A;  1TZE E;  1O4P A;  1SHD A;  2PNB A;  1AYC A;  1O46 A;  4JGH A;  1A1E A;  1LUN A;  3S8O A;  1LUI A;  1ZFP E;  2ETZ A;  1O4A A;  1AB2 A;  2CRH A;  3HCK A;  2AOA A;  1NZL A;  4H1O A;  5AUL A;  4U17 A;  5I6V A;  1O4J A;  1BKM A;  4GL9 E;  1SPS A;  1R1P A;  3OVE A;  1O4C A;  5KAZ A;  4E93 A;  1G83 A;  1QG1 E;  1KA6 A;  1A08 A;  3VRQ A;  3PS5 A;  3CD3 A;  1R1Q A;  1NRV A;  1SHA A;  2L4K A;  3VS2 A;  3VS4 A;  3VRZ A;  1FMK A;  1FHS A;  3BUN B;  1LKK A;  2PTK A;  4P9V A;  2L3T A;  3QWX X;  2K7A B;  3PLF B;  3UF4 A;  3T04 A;  1BFI A;  1BG1 A;  1CWE A;  3TL0 A;  2Y3A B;  1D4W A;  2Y1M A;  4L1B B;  4GPL B;  2OZO A;  5HKY A;  2MRJ A;  3VS6 A;  1NZV A;  1MIL A;  2CI9 A;  2MQI A;  4OHD A;  1AOT F;  3GQI B;  4JE4 A;  3PSJ A;  1OO3 A;  5BO4 A;  4EY0 A;  3CBL A;  1BLK A;  2B3O A;  3PQZ A;  2ROR A;  2DVJ A;  2C9W A;  5AXI A;  5HKZ A;  3US4 A;  5EEL A;  2CIA A;  3BUO B;  3N7Y A;  5EHR A;  1LCJ A;  3ZNI A;  2CBL A;  1O41 A;  1WQU A;  4K45 A;  1RPY A;  5J3X A;  1FU6 A;  4XZ1 A;  2SHP A;  4F5A A;  1O4N A;  3IN7 A;  3K2M A;  1K9A A;  4OHL A;  1BLJ A;  4OHE A;  1FU5 A;  2ECD A;  1O48 A;  1BM2 A;  2IUI A;  2HDV A;  4NWG A;  1M61 A;  1F1W A;  2DM0 A;  4DGP A;  1O4O A;  1OPL A;  4LUE A;  2CR4 A;  4QSY A;  1O4M A;  1Y57 A;  4K2R A;  1UUR A;  2C0I A;  2EKX A;  1HCT B;  2CI8 A;  1BHH A;  2DX0 A;  1F2F A;  4GWF A;  1QAD A;  2LQW A;  3M7F A;  1SKJ A;  1TCE A;  2DLY A;  1O4G A;  3S8N A;  1O4L A;  1YVH A;  3N84 A;  1KC2 A;  3OB2 B;  1JYU A;  1AYB A;  1IJR A;  1O4F A;  3VRN A;  1R1S A;  1X27 A;  1BFJ A;  2CS0 A;  2Y1N A;  5EG3 B;  4A4C A;  3EAZ A;  1O4E A;  1JWO A;  3VS7 A;  3VGO A;  4JEG A;  3UYO A;  3GXX A;  5GJH A;  1GHU A;  1LCK A;  3IN8 A;  3MXY A;  4F59 A;  2EO3 A;  3VS1 A;  3TKZ A;  4A4B A;  2LNW A;  1GRI A;  1BF5 A;  3VS3 A;  3CWG A;  3OV1 A;  3PFV A;  3VS0 A;  2HCK A;  2EU0 A;  1CSZ A;  4K44 A;  2K79 B;  2HUW A;  1O4Q A;  1A81 A;  1X6C A;  2HMH A;  2C0O A;  3BUW B;  1O42 A;  3WA4 A;  5EHP A;  3IMJ A;  4OHI A;  5HKW A;  1AOU F;  3S8L A;  2RSY A;  3VRY A;  1X0N A;  1XA6 A;  2MRK A;  4ROJ A;  5GJI A;  3PSK A;  2EOB A;  1D4T A;  1A1B A;  4XZ0 A;  4FL2 A;  1O45 A;  1YVL A;  1BKL A;  1O4R A;  5D0J A;  3VS5 A;  1O47 A;  4LUD A;  1FBZ A;  2SRC A;  1FYR A;  2DLZ A;  1LUM A;  4H34 A;  3HHM B;  1CJ1 A;  5DC0 B;  4M4Z A;  1BMB A;  1FBV A;  2IZV A;  2AUG A;  1O49 A;  2YSX A;  1M27 A;  1P13 A;  4U1P A;  2L6K A;  1BHF A;  1A1A A;  2LNX A;  2H46 E;  2PLE A;  5IBS A;  1H9O A;  4K11 A;  1QCF A;  2PNA A;  1O4B A;  1D1Z A;  1AYA A;  1O44 A;  3S9K A;  2PLD A;  2MK2 A;  1Y1U A;  1O4D A;  4OHH A;  2MC1 A;  3CXL A;  2EYZ A;  3MAZ A;  3N8M A;  4FL3 A;  3MXC A;  1RJA A;  5EEQ A;  1OO4 A;  1B47 A;  1SPR A;  3OP0 A;  5DC9 A;  5DC4 A;  2AOB A;  2C0T A;  2OQ1 A;  1JYQ A;  3OB1 B;  3QWY A;  2LQN A;  1RQQ C;  3KFJ A;  2RVF A;  3BUM B;  2H5K A;  1O4K A;  1KA7 A;  2RMX A;  2FCI A;  4D8K A;  1A1C A;  1AYD A;  2XP1 A;  2H8H A;  1IS0 A;  1O4H A;  3BUX B;  2YU7 A;  3VRO A;  1CSY A;  2EYV A;  1BHH B;  1Z3K A;  2BBU A;  5DF6 A;  1OPK A;  1O43 A;  5CDW A;  2ABL A;  4EIH A;  2EO6 A;  4DGX A;  3VRR A;  4F5B A;  1PIC A;  2JYQ A;  2EYY A;  2VIF A;  4NWF A;  2KNO A;  3IMD A;  4WWQ A;  1I3Z A;  1HCS B;  3GXW A;  4E68 A;  3NHN A;  1AD5 A;  2GSB A;  1A07 A;  1KSW A;  2DCR A;  4TZI A;  1SHB A;  2FO0 A;  2KK6 A;  1CWD L;  1JU5 A;  2QMS A;  3HIZ B;  2EL8 A;  4P9Z A;  4X6S A;  3EAC A;  1LKL A;  2GE9 A;  2LCT A;  1MW4 A;  1O4I A;  3BKB A;  3C7I A;  5IBM A;  2IUG A;  4FBN A;  3VRP A;  2HDX A;  2IUH A;  1JYR A; 
#chains in the Genus database with same CATH topology
 1A09 A;  1LUK A;  3PJP A;  1UUS A;  1TZE E;  1O4P A;  1SHD A;  2PNB A;  1AYC A;  1O46 A;  4JGH A;  1A1E A;  1LUN A;  3S8O A;  1LUI A;  1ZFP E;  2ETZ A;  1O4A A;  1AB2 A;  2CRH A;  3HCK A;  2AOA A;  1NZL A;  4H1O A;  5AUL A;  4U17 A;  5I6V A;  1O4J A;  1BKM A;  4GL9 E;  1SPS A;  1R1P A;  3OVE A;  1O4C A;  5KAZ A;  4E93 A;  1G83 A;  1QG1 E;  1KA6 A;  1A08 A;  3VRQ A;  3PS5 A;  3CD3 A;  1R1Q A;  1NRV A;  2KGY A;  1SHA A;  2L4K A;  3VS2 A;  3VS4 A;  3VRZ A;  1FMK A;  1FHS A;  3BUN B;  1LKK A;  2PTK A;  4P9V A;  2L3T A;  3QWX X;  2K7A B;  3PLF B;  3UF4 A;  3T04 A;  1BFI A;  1BG1 A;  2LRA A;  1CWE A;  3TL0 A;  2Y3A B;  1D4W A;  2Y1M A;  4L1B B;  4GPL B;  2OZO A;  5HKY A;  2MRJ A;  3VS6 A;  1NZV A;  1MIL A;  2CI9 A;  2MQI A;  4OHD A;  1AOT F;  3GQI B;  4JE4 A;  3PSJ A;  1OO3 A;  5BO4 A;  4EY0 A;  3CBL A;  1BLK A;  2B3O A;  3PQZ A;  2ROR A;  2DVJ A;  2C9W A;  5AXI A;  5HKZ A;  3US4 A;  5EEL A;  2CIA A;  3BUO B;  3N7Y A;  5EHR A;  1LCJ A;  3ZNI A;  2CBL A;  1O41 A;  1WQU A;  4K45 A;  1RPY A;  5J3X A;  1FU6 A;  4XZ1 A;  2SHP A;  4F5A A;  1O4N A;  3IN7 A;  3K2M A;  1K9A A;  4OHL A;  1BLJ A;  4OHE A;  1FU5 A;  2ECD A;  1O48 A;  1BM2 A;  2IUI A;  2HDV A;  4NWG A;  1M61 A;  1F1W A;  2DM0 A;  4DGP A;  1O4O A;  1OPL A;  4LUE A;  2CR4 A;  4QSY A;  1O4M A;  1Y57 A;  4K2R A;  1UUR A;  2C0I A;  2EKX A;  1HCT B;  2CI8 A;  1BHH A;  2DX0 A;  1F2F A;  4GWF A;  1QAD A;  2LQW A;  3M7F A;  1SKJ A;  1TCE A;  2DLY A;  1O4G A;  3S8N A;  1O4L A;  1YVH A;  3N84 A;  1KC2 A;  3OB2 B;  1JYU A;  1AYB A;  1IJR A;  1O4F A;  3VRN A;  1R1S A;  1X27 A;  1BFJ A;  2CS0 A;  3LYV A;  2Y1N A;  5EG3 B;  4A4C A;  3EAZ A;  1O4E A;  1JWO A;  3VS7 A;  3VGO A;  4JEG A;  3UYO A;  3GXX A;  5GJH A;  1GHU A;  1LCK A;  3IN8 A;  3MXY A;  4F59 A;  2EO3 A;  3VS1 A;  3TKZ A;  4A4B A;  2LNW A;  1GRI A;  1BF5 A;  3VS3 A;  3CWG A;  3OV1 A;  3PFV A;  3VS0 A;  2HCK A;  2EU0 A;  1CSZ A;  4K44 A;  2K79 B;  2HUW A;  1O4Q A;  1A81 A;  1X6C A;  2HMH A;  2C0O A;  3BUW B;  3K2T A;  1O42 A;  3WA4 A;  5EHP A;  3IMJ A;  4OHI A;  5HKW A;  1AOU F;  3S8L A;  2RSY A;  3VRY A;  1X0N A;  1XA6 A;  2MRK A;  4ROJ A;  5GJI A;  3PSK A;  2EOB A;  1D4T A;  1A1B A;  4XZ0 A;  4FL2 A;  1O45 A;  1YVL A;  1BKL A;  1O4R A;  5D0J A;  3VS5 A;  1O47 A;  4LUD A;  1FBZ A;  2SRC A;  1FYR A;  2DLZ A;  1LUM A;  4H34 A;  3HHM B;  1CJ1 A;  5DC0 B;  4M4Z A;  1BMB A;  1FBV A;  2IZV A;  2AUG A;  1O49 A;  2YSX A;  1M27 A;  1P13 A;  4U1P A;  2L6K A;  1BHF A;  1A1A A;  2LNX A;  2H46 E;  2PLE A;  5IBS A;  1H9O A;  4K11 A;  1QCF A;  2PNA A;  1O4B A;  1D1Z A;  1AYA A;  1O44 A;  3S9K A;  2PLD A;  2MK2 A;  1Y1U A;  1O4D A;  4OHH A;  2MC1 A;  3CXL A;  2EYZ A;  3MAZ A;  3N8M A;  4FL3 A;  3MXC A;  1RJA A;  5EEQ A;  1OO4 A;  1B47 A;  1SPR A;  3OP0 A;  5DC9 A;  5DC4 A;  2AOB A;  2C0T A;  2OQ1 A;  1JYQ A;  3OB1 B;  3QWY A;  2LQN A;  1RQQ C;  3KFJ A;  2RVF A;  3BUM B;  2H5K A;  1O4K A;  1KA7 A;  2RMX A;  2FCI A;  4D8K A;  1A1C A;  1AYD A;  2XP1 A;  2H8H A;  1IS0 A;  1O4H A;  3BUX B;  2YU7 A;  3VRO A;  1CSY A;  2EYV A;  1BHH B;  1Z3K A;  2BBU A;  5DF6 A;  1OPK A;  1O43 A;  5CDW A;  2ABL A;  4EIH A;  2EO6 A;  4DGX A;  3VRR A;  4F5B A;  1PIC A;  2JYQ A;  2EYY A;  2VIF A;  4NWF A;  2KNO A;  3IMD A;  4WWQ A;  1I3Z A;  1HCS B;  3GXW A;  4E68 A;  3NHN A;  1AD5 A;  2GSB A;  1A07 A;  1KSW A;  2DCR A;  4TZI A;  1SHB A;  2FO0 A;  2KK6 A;  1CWD L;  1JU5 A;  2QMS A;  3HIZ B;  2EL8 A;  4P9Z A;  4X6S A;  3EAC A;  1LKL A;  2GE9 A;  2LCT A;  1MW4 A;  1O4I A;  3BKB A;  3C7I A;  5IBM A;  2IUG A;  4FBN A;  3VRP A;  2HDX A;  2IUH A;  1JYR A; 
#chains in the Genus database with same CATH homology
 1A09 A;  1LUK A;  3PJP A;  1UUS A;  1TZE E;  1O4P A;  1SHD A;  2PNB A;  1AYC A;  1O46 A;  4JGH A;  1A1E A;  1LUN A;  3S8O A;  1LUI A;  1ZFP E;  2ETZ A;  1O4A A;  1AB2 A;  2CRH A;  3HCK A;  2AOA A;  1NZL A;  4H1O A;  5AUL A;  4U17 A;  5I6V A;  1O4J A;  1BKM A;  4GL9 E;  1SPS A;  1R1P A;  3OVE A;  1O4C A;  5KAZ A;  4E93 A;  1G83 A;  1QG1 E;  1KA6 A;  1A08 A;  3VRQ A;  3PS5 A;  3CD3 A;  1R1Q A;  1NRV A;  1SHA A;  2L4K A;  3VS2 A;  3VS4 A;  3VRZ A;  1FMK A;  1FHS A;  3BUN B;  1LKK A;  2PTK A;  4P9V A;  2L3T A;  3QWX X;  2K7A B;  3PLF B;  3UF4 A;  3T04 A;  1BFI A;  1BG1 A;  1CWE A;  3TL0 A;  2Y3A B;  1D4W A;  2Y1M A;  4L1B B;  4GPL B;  2OZO A;  5HKY A;  2MRJ A;  3VS6 A;  1NZV A;  1MIL A;  2CI9 A;  2MQI A;  4OHD A;  1AOT F;  3GQI B;  4JE4 A;  3PSJ A;  1OO3 A;  5BO4 A;  4EY0 A;  3CBL A;  1BLK A;  2B3O A;  3PQZ A;  2ROR A;  2DVJ A;  2C9W A;  5AXI A;  5HKZ A;  3US4 A;  5EEL A;  2CIA A;  3BUO B;  3N7Y A;  5EHR A;  1LCJ A;  3ZNI A;  2CBL A;  1O41 A;  1WQU A;  4K45 A;  1RPY A;  5J3X A;  1FU6 A;  4XZ1 A;  2SHP A;  4F5A A;  1O4N A;  3IN7 A;  3K2M A;  1K9A A;  4OHL A;  1BLJ A;  4OHE A;  1FU5 A;  2ECD A;  1O48 A;  1BM2 A;  2IUI A;  2HDV A;  4NWG A;  1M61 A;  1F1W A;  2DM0 A;  4DGP A;  1O4O A;  1OPL A;  4LUE A;  2CR4 A;  4QSY A;  1O4M A;  1Y57 A;  4K2R A;  1UUR A;  2C0I A;  2EKX A;  1HCT B;  2CI8 A;  1BHH A;  2DX0 A;  1F2F A;  4GWF A;  1QAD A;  2LQW A;  3M7F A;  1SKJ A;  1TCE A;  2DLY A;  1O4G A;  3S8N A;  1O4L A;  1YVH A;  3N84 A;  1KC2 A;  3OB2 B;  1JYU A;  1AYB A;  1IJR A;  1O4F A;  3VRN A;  1R1S A;  1X27 A;  1BFJ A;  2CS0 A;  2Y1N A;  5EG3 B;  4A4C A;  3EAZ A;  1O4E A;  1JWO A;  3VS7 A;  3VGO A;  4JEG A;  3UYO A;  3GXX A;  5GJH A;  1GHU A;  1LCK A;  3IN8 A;  3MXY A;  4F59 A;  2EO3 A;  3VS1 A;  3TKZ A;  4A4B A;  2LNW A;  1GRI A;  1BF5 A;  3VS3 A;  3CWG A;  3OV1 A;  3PFV A;  3VS0 A;  2HCK A;  2EU0 A;  1CSZ A;  4K44 A;  2K79 B;  2HUW A;  1O4Q A;  1A81 A;  1X6C A;  2HMH A;  2C0O A;  3BUW B;  1O42 A;  3WA4 A;  5EHP A;  3IMJ A;  4OHI A;  5HKW A;  1AOU F;  3S8L A;  2RSY A;  3VRY A;  1X0N A;  1XA6 A;  2MRK A;  4ROJ A;  5GJI A;  3PSK A;  2EOB A;  1D4T A;  1A1B A;  4XZ0 A;  4FL2 A;  1O45 A;  1YVL A;  1BKL A;  1O4R A;  5D0J A;  3VS5 A;  1O47 A;  4LUD A;  1FBZ A;  2SRC A;  1FYR A;  2DLZ A;  1LUM A;  4H34 A;  3HHM B;  1CJ1 A;  5DC0 B;  4M4Z A;  1BMB A;  1FBV A;  2IZV A;  2AUG A;  1O49 A;  2YSX A;  1M27 A;  1P13 A;  4U1P A;  2L6K A;  1BHF A;  1A1A A;  2LNX A;  2H46 E;  2PLE A;  5IBS A;  1H9O A;  4K11 A;  1QCF A;  2PNA A;  1O4B A;  1D1Z A;  1AYA A;  1O44 A;  3S9K A;  2PLD A;  2MK2 A;  1Y1U A;  1O4D A;  4OHH A;  2MC1 A;  3CXL A;  2EYZ A;  3MAZ A;  3N8M A;  4FL3 A;  3MXC A;  1RJA A;  5EEQ A;  1OO4 A;  1B47 A;  1SPR A;  3OP0 A;  5DC9 A;  5DC4 A;  2AOB A;  2C0T A;  2OQ1 A;  1JYQ A;  3OB1 B;  3QWY A;  2LQN A;  1RQQ C;  3KFJ A;  2RVF A;  3BUM B;  2H5K A;  1O4K A;  1KA7 A;  2RMX A;  2FCI A;  4D8K A;  1A1C A;  1AYD A;  2XP1 A;  2H8H A;  1IS0 A;  1O4H A;  3BUX B;  2YU7 A;  3VRO A;  1CSY A;  2EYV A;  1BHH B;  1Z3K A;  2BBU A;  5DF6 A;  1OPK A;  1O43 A;  5CDW A;  2ABL A;  4EIH A;  2EO6 A;  4DGX A;  3VRR A;  4F5B A;  1PIC A;  2JYQ A;  2EYY A;  2VIF A;  4NWF A;  2KNO A;  3IMD A;  4WWQ A;  1I3Z A;  1HCS B;  3GXW A;  4E68 A;  3NHN A;  1AD5 A;  2GSB A;  1A07 A;  1KSW A;  2DCR A;  4TZI A;  1SHB A;  2FO0 A;  2KK6 A;  1CWD L;  1JU5 A;  2QMS A;  3HIZ B;  2EL8 A;  4P9Z A;  4X6S A;  3EAC A;  1LKL A;  2GE9 A;  2LCT A;  1MW4 A;  1O4I A;  3BKB A;  3C7I A;  5IBM A;  2IUG A;  4FBN A;  3VRP A;  2HDX A;  2IUH A;  1JYR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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