1O4AA

Crystal structure of sh2 in complex with ru82197.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4aA00
3N7YA 5DC4A 3VS4A 2AOAA 1AYBA 2CIAA 4NWGA 1BLKA 1BHHB 4E68A 1R1SA 4EY0A 1HCSB 1D4WA 3HCKA 4OHEA 5EELA 1O4JA 4L1BB 1UURA 1BMBA 2CI9A 1O43A 3ZNIA 4H34A 1A07A 4ROJA 2LQWA 1AYDA 4P9VA 3PLFB 1SPSA 1O4AA 2MK2A 3PSKA 4XZ1A 1FHSA 1CJ1A 5HKZA 1O42A 1CSZA 4GL9E 1F2FA 1K9AA 1P13A 2CS0A 3PJPA 1SHDA 4A4CA 2RSYA 2CR4A 3TL0A 3S8NA 1A1BA 2IUGA 3PS5A 1BKLA 2AUGA 3TKZA 2DCRA 1O4LA 2RVFA 4GPLB 1D4TA 3PSJA 2EYVA 1LUNA 1O45A 2C0TA 2EYYA 1XA6A 4U17A 2SRCA 1JU5A 3K2MA 2EO6A 2FO0A 1O4CA 1A08A 1OPKA 1AOTF 4K11A 3T04A 3GXXA 4LUDA 2H5KA 4FL3A 1PICA 5DC9A 1KSWA 4GWFA 2BBUA 2Y3AB 2DVJA 1O44A 4WWQA 1A09A 1Y1UA 3HHMB 2IZVA 5AXIA 5DF6A 3IMJA 3PQZA 2QMSA 3BUOB 3VS7A 1OO4A 1BKMA 1SHBA 3M7FA 2KK6A 5AULA 1BFJA 1LUIA 1QG1E 1OO3A 3VGOA 3VRNA 5EHPA 1MILA 1BF5A 2YSXA 1WQUA 3GXWA 4A4BA 4D8KA 2CBLA 1BFIA 5CDWA 1O41A 5HKWA 3BUNB 3GQIB 1AYCA 1TCEA 1M27A 3VROA 1YVHA 1LKLA 1JYQA 1UUSA 1O4PA 2CI8A 1KA6A 2IUHA 2C9WA 1O4HA 4OHDA 2LNWA 1QADA 1BHHA 1O4OA 1IJRA 1LCKA 4NWFA 3N84A 1SHAA 3C7IA 5EG3B 2EL8A 2Y1MA 1A1EA 1JWOA 1FU5A 1CWEA 1FMKA 3EACA 1R1QA 1YVLA 2MRKA 5IBSA 3UF4A 3VS6A 3N8MA 4FL2A 3MXYA 1FBVA 1CWDL 5EEQA 2DLYA 3CD3A 1AYAA 3VRYA 2YU7A 2IUIA 1O4KA 2HDXA 4F59A 3NHNA 3VS5A 1R1PA 2ECDA 2RMXA 1LUMA 1D1ZA 1RQQC 4XZ0A 1BG1A 3VS3A 1O4RA 1O48A 1O4NA 2FCIA 3BKBA 1O4QA 4X6SA 1RPYA 3KFJA 1SKJA 2L4KA 2ETZA 3QWXX 5GJHA 2AOBA 3OVEA 1HCTB 1FU6A 1O47A 3IN7A 1JYUA 2DM0A 3CWGA 1IS0A 1H9OA 3BUMB 5KAZA 1GHUA 1LUKA 3S9KA 1KA7A 4QSYA 1RJAA 1AD5A 2MQIA 1O49A 1AOUF 1GRIA 2XP1A 4EIHA 2C0OA 3QWYA 3WA4A 2PLDA 1QCFA 5GJIA 1O4MA 3PFVA 4LUEA 3VS0A 4U1PA 5DC0B 2EU0A 1A81A 2LQNA 1NZVA 2HDVA 1O4BA 3OB2B 2K79B 2B3OA 1NZLA 3S8OA 3VRPA 1AB2A 1Z3KA 1CSYA 4JE4A 2L3TA 5I6VA 1MW4A 3VRZA 1LCJA 2DX0A 2H8HA 2HUWA 3MAZA 2OQ1A 4K44A 2PLEA 1O4EA 1X27A 1BLJA 2EKXA 3BUWB 1BM2A 1JYRA 3IMDA 1O46A 2JYQA 5BO4A 2DLZA 4OHLA 2K7AB 2C0IA 2RORA 1FYRA 2Y1NA 4E93A 4OHIA 1Y57A 3HIZB 4DGPA 3VRQA 1ZFPE 3US4A 3VRRA 5D0JA 1NRVA 1A1CA 4JEGA 3IN8A 1OPLA 2LCTA 2CRHA 1B47A 4H1OA 1A1AA 4M4ZA 2KNOA 4OHHA 1M61A 2SHPA 3VS2A 1X0NA 3S8LA 4P9ZA 2PTKA 5HKYA 4DGXA 2EOBA 1TZEE 3UYOA 1O4DA 2EYZA 1FBZA 3VS1A 2GE9A 3OP0A 2PNAA 2L6KA 1O4GA 4K2RA 3MXCA 2HMHA 2LNXA 3OB1B 4F5AA 1G83A 3BUXB 1SPRA 1BHFA 5EHRA 2OZOA 2MRJA 2VIFA 4K45A 2H46E 1O4IA 3CXLA 5IBMA 2HCKA 1LKKA 2GSBA 1I3ZA 2PNBA 1X6CA 1F1WA 1KC2A 2MC1A 3EAZA 3CBLA 2ABLA 4F5BA 4JGHA 4TZIA 5J3XA 4FBNA 2EO3A 3OV1A 1O4FA
chains in the Genus database with same CATH superfamily
3N7YA 5DC4A 3VS4A 2AOAA 1AYBA 2CIAA 4NWGA 1BLKA 1BHHB 4E68A 1R1SA 3LYVA 4EY0A 1HCSB 1D4WA 3HCKA 4OHEA 5EELA 1O4JA 4L1BB 1UURA 1BMBA 2CI9A 1O43A 3ZNIA 4H34A 1A07A 4ROJA 2LQWA 1AYDA 4P9VA 3PLFB 1SPSA 1O4AA 2MK2A 3PSKA 4XZ1A 1FHSA 1CJ1A 5HKZA 1O42A 1CSZA 4GL9E 1F2FA 1K9AA 1P13A 2CS0A 3PJPA 1SHDA 4A4CA 2RSYA 2CR4A 3TL0A 3S8NA 1A1BA 2IUGA 3PS5A 1BKLA 2AUGA 3TKZA 2DCRA 1O4LA 2RVFA 4GPLB 1D4TA 3PSJA 2EYVA 1LUNA 1O45A 2C0TA 2EYYA 1XA6A 4U17A 2SRCA 1JU5A 3K2MA 2EO6A 2FO0A 1O4CA 1A08A 1OPKA 1AOTF 4K11A 3T04A 3GXXA 4LUDA 2H5KA 4FL3A 1PICA 5DC9A 1KSWA 4GWFA 2BBUA 2Y3AB 2DVJA 1O44A 4WWQA 1A09A 1Y1UA 3HHMB 2IZVA 5AXIA 5DF6A 3IMJA 3PQZA 2QMSA 3BUOB 3VS7A 1OO4A 1BKMA 1SHBA 3M7FA 2KK6A 5AULA 1BFJA 1LUIA 1QG1E 1OO3A 3VGOA 3VRNA 5EHPA 1MILA 1BF5A 2YSXA 1WQUA 3GXWA 4A4BA 4D8KA 2CBLA 1BFIA 5CDWA 1O41A 5HKWA 3BUNB 3GQIB 1AYCA 1TCEA 1M27A 3VROA 1YVHA 1LKLA 1JYQA 1UUSA 1O4PA 2CI8A 1KA6A 2IUHA 2C9WA 1O4HA 4OHDA 2LNWA 1QADA 1BHHA 1O4OA 1IJRA 1LCKA 4NWFA 3N84A 1SHAA 3C7IA 5EG3B 2EL8A 2Y1MA 1A1EA 1JWOA 1FU5A 1CWEA 1FMKA 3EACA 1R1QA 1YVLA 2MRKA 5IBSA 3UF4A 3VS6A 3N8MA 4FL2A 3MXYA 1FBVA 1CWDL 5EEQA 2DLYA 3CD3A 1AYAA 3VRYA 2YU7A 2IUIA 1O4KA 2HDXA 4F59A 3NHNA 3VS5A 1R1PA 2ECDA 2RMXA 1LUMA 1D1ZA 1RQQC 4XZ0A 1BG1A 3VS3A 1O4RA 1O48A 1O4NA 2FCIA 3BKBA 1O4QA 4X6SA 1RPYA 3KFJA 1SKJA 2L4KA 2ETZA 3QWXX 5GJHA 2AOBA 3OVEA 1HCTB 1FU6A 1O47A 3IN7A 1JYUA 2DM0A 3CWGA 1IS0A 1H9OA 3BUMB 5KAZA 2KGYA 1GHUA 1LUKA 3S9KA 1KA7A 4QSYA 1RJAA 1AD5A 2MQIA 1O49A 1AOUF 1GRIA 2XP1A 4EIHA 2C0OA 3QWYA 3WA4A 2PLDA 1QCFA 5GJIA 1O4MA 3PFVA 4LUEA 3VS0A 4U1PA 5DC0B 3K2TA 2EU0A 1A81A 2LQNA 1NZVA 2HDVA 1O4BA 3OB2B 2K79B 2B3OA 1NZLA 3S8OA 3VRPA 1AB2A 1Z3KA 1CSYA 4JE4A 2L3TA 5I6VA 1MW4A 3VRZA 1LCJA 2DX0A 2H8HA 2HUWA 3MAZA 2OQ1A 4K44A 2PLEA 1O4EA 1X27A 1BLJA 2EKXA 3BUWB 1BM2A 1JYRA 3IMDA 1O46A 2JYQA 5BO4A 2DLZA 4OHLA 2K7AB 2C0IA 2RORA 1FYRA 2Y1NA 4E93A 4OHIA 1Y57A 3HIZB 4DGPA 3VRQA 1ZFPE 3US4A 3VRRA 5D0JA 1NRVA 1A1CA 4JEGA 3IN8A 1OPLA 2LCTA 2CRHA 1B47A 4H1OA 1A1AA 4M4ZA 2KNOA 4OHHA 1M61A 2SHPA 3VS2A 1X0NA 3S8LA 4P9ZA 2PTKA 5HKYA 4DGXA 2EOBA 1TZEE 3UYOA 1O4DA 2EYZA 1FBZA 3VS1A 2GE9A 3OP0A 2PNAA 2L6KA 1O4GA 4K2RA 3MXCA 2HMHA 2LNXA 3OB1B 4F5AA 1G83A 3BUXB 1SPRA 1BHFA 5EHRA 2OZOA 2MRJA 2VIFA 4K45A 2H46E 1O4IA 3CXLA 5IBMA 2HCKA 1LKKA 2GSBA 1I3ZA 2PNBA 1X6CA 2LRAA 1F1WA 1KC2A 2MC1A 3EAZA 3CBLA 2ABLA 4F5BA 4JGHA 4TZIA 5J3XA 4FBNA 2EO3A 3OV1A 1O4FA
chains in the Genus database with same CATH topology
3N7YA 5DC4A 3VS4A 2AOAA 1AYBA 2CIAA 4NWGA 1BLKA 1BHHB 4E68A 1R1SA 4EY0A 1HCSB 1D4WA 3HCKA 4OHEA 5EELA 1O4JA 4L1BB 1UURA 1BMBA 2CI9A 1O43A 3ZNIA 4H34A 1A07A 4ROJA 2LQWA 1AYDA 4P9VA 3PLFB 1SPSA 1O4AA 2MK2A 3PSKA 4XZ1A 1FHSA 1CJ1A 5HKZA 1O42A 1CSZA 4GL9E 1F2FA 1K9AA 1P13A 2CS0A 3PJPA 1SHDA 4A4CA 2RSYA 2CR4A 3TL0A 3S8NA 1A1BA 2IUGA 3PS5A 1BKLA 2AUGA 3TKZA 2DCRA 1O4LA 2RVFA 4GPLB 1D4TA 3PSJA 2EYVA 1LUNA 1O45A 2C0TA 2EYYA 1XA6A 4U17A 2SRCA 1JU5A 3K2MA 2EO6A 2FO0A 1O4CA 1A08A 1OPKA 1AOTF 4K11A 3T04A 3GXXA 4LUDA 2H5KA 4FL3A 1PICA 5DC9A 1KSWA 4GWFA 2BBUA 2Y3AB 2DVJA 1O44A 4WWQA 1A09A 1Y1UA 3HHMB 2IZVA 5AXIA 5DF6A 3IMJA 3PQZA 2QMSA 3BUOB 3VS7A 1OO4A 1BKMA 1SHBA 3M7FA 2KK6A 5AULA 1BFJA 1LUIA 1QG1E 1OO3A 3VGOA 3VRNA 5EHPA 1MILA 1BF5A 2YSXA 1WQUA 3GXWA 4A4BA 4D8KA 2CBLA 1BFIA 5CDWA 1O41A 5HKWA 3BUNB 3GQIB 1AYCA 1TCEA 1M27A 3VROA 1YVHA 1LKLA 1JYQA 1UUSA 1O4PA 2CI8A 1KA6A 2IUHA 2C9WA 1O4HA 4OHDA 2LNWA 1QADA 1BHHA 1O4OA 1IJRA 1LCKA 4NWFA 3N84A 1SHAA 3C7IA 5EG3B 2EL8A 2Y1MA 1A1EA 1JWOA 1FU5A 1CWEA 1FMKA 3EACA 1R1QA 1YVLA 2MRKA 5IBSA 3UF4A 3VS6A 3N8MA 4FL2A 3MXYA 1FBVA 1CWDL 5EEQA 2DLYA 3CD3A 1AYAA 3VRYA 2YU7A 2IUIA 1O4KA 2HDXA 4F59A 3NHNA 3VS5A 1R1PA 2ECDA 2RMXA 1LUMA 1D1ZA 1RQQC 4XZ0A 1BG1A 3VS3A 1O4RA 1O48A 1O4NA 2FCIA 3BKBA 1O4QA 4X6SA 1RPYA 3KFJA 1SKJA 2L4KA 2ETZA 3QWXX 5GJHA 2AOBA 3OVEA 1HCTB 1FU6A 1O47A 3IN7A 1JYUA 2DM0A 3CWGA 1IS0A 1H9OA 3BUMB 5KAZA 1GHUA 1LUKA 3S9KA 1KA7A 4QSYA 1RJAA 1AD5A 2MQIA 1O49A 1AOUF 1GRIA 2XP1A 4EIHA 2C0OA 3QWYA 3WA4A 2PLDA 1QCFA 5GJIA 1O4MA 3PFVA 4LUEA 3VS0A 4U1PA 5DC0B 2EU0A 1A81A 2LQNA 1NZVA 2HDVA 1O4BA 3OB2B 2K79B 2B3OA 1NZLA 3S8OA 3VRPA 1AB2A 1Z3KA 1CSYA 4JE4A 2L3TA 5I6VA 1MW4A 3VRZA 1LCJA 2DX0A 2H8HA 2HUWA 3MAZA 2OQ1A 4K44A 2PLEA 1O4EA 1X27A 1BLJA 2EKXA 3BUWB 1BM2A 1JYRA 3IMDA 1O46A 2JYQA 5BO4A 2DLZA 4OHLA 2K7AB 2C0IA 2RORA 1FYRA 2Y1NA 4E93A 4OHIA 1Y57A 3HIZB 4DGPA 3VRQA 1ZFPE 3US4A 3VRRA 5D0JA 1NRVA 1A1CA 4JEGA 3IN8A 1OPLA 2LCTA 2CRHA 1B47A 4H1OA 1A1AA 4M4ZA 2KNOA 4OHHA 1M61A 2SHPA 3VS2A 1X0NA 3S8LA 4P9ZA 2PTKA 5HKYA 4DGXA 2EOBA 1TZEE 3UYOA 1O4DA 2EYZA 1FBZA 3VS1A 2GE9A 3OP0A 2PNAA 2L6KA 1O4GA 4K2RA 3MXCA 2HMHA 2LNXA 3OB1B 4F5AA 1G83A 3BUXB 1SPRA 1BHFA 5EHRA 2OZOA 2MRJA 2VIFA 4K45A 2H46E 1O4IA 3CXLA 5IBMA 2HCKA 1LKKA 2GSBA 1I3ZA 2PNBA 1X6CA 1F1WA 1KC2A 2MC1A 3EAZA 3CBLA 2ABLA 4F5BA 4JGHA 4TZIA 5J3XA 4FBNA 2EO3A 3OV1A 1O4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N7Y A;  5DC4 A;  3VS4 A;  2AOA A;  1AYB A;  2CIA A;  4NWG A;  1BLK A;  1BHH B;  4E68 A;  1R1S A;  4EY0 A;  1HCS B;  1D4W A;  3HCK A;  4OHE A;  5EEL A;  1O4J A;  4L1B B;  1UUR A;  1BMB A;  2CI9 A;  1O43 A;  3ZNI A;  4H34 A;  1A07 A;  4ROJ A;  2LQW A;  1AYD A;  4P9V A;  3PLF B;  1SPS A;  1O4A A;  2MK2 A;  3PSK A;  4XZ1 A;  1FHS A;  1CJ1 A;  5HKZ A;  1O42 A;  1CSZ A;  4GL9 E;  1F2F A;  1K9A A;  1P13 A;  2CS0 A;  3PJP A;  1SHD A;  4A4C A;  2RSY A;  2CR4 A;  3TL0 A;  3S8N A;  1A1B A;  2IUG A;  3PS5 A;  1BKL A;  2AUG A;  3TKZ A;  2DCR A;  1O4L A;  2RVF A;  4GPL B;  1D4T A;  3PSJ A;  2EYV A;  1LUN A;  1O45 A;  2C0T A;  2EYY A;  1XA6 A;  4U17 A;  2SRC A;  1JU5 A;  3K2M A;  2EO6 A;  2FO0 A;  1O4C A;  1A08 A;  1OPK A;  1AOT F;  4K11 A;  3T04 A;  3GXX A;  4LUD A;  2H5K A;  4FL3 A;  1PIC A;  5DC9 A;  1KSW A;  4GWF A;  2BBU A;  2Y3A B;  2DVJ A;  1O44 A;  4WWQ A;  1A09 A;  1Y1U A;  3HHM B;  2IZV A;  5AXI A;  5DF6 A;  3IMJ A;  3PQZ A;  2QMS A;  3BUO B;  3VS7 A;  1OO4 A;  1BKM A;  1SHB A;  3M7F A;  2KK6 A;  5AUL A;  1BFJ A;  1LUI A;  1QG1 E;  1OO3 A;  3VGO A;  3VRN A;  5EHP A;  1MIL A;  1BF5 A;  2YSX A;  1WQU A;  3GXW A;  4A4B A;  4D8K A;  2CBL A;  1BFI A;  5CDW A;  1O41 A;  5HKW A;  3BUN B;  3GQI B;  1AYC A;  1TCE A;  1M27 A;  3VRO A;  1YVH A;  1LKL A;  1JYQ A;  1UUS A;  1O4P A;  2CI8 A;  1KA6 A;  2IUH A;  2C9W A;  1O4H A;  4OHD A;  2LNW A;  1QAD A;  1BHH A;  1O4O A;  1IJR A;  1LCK A;  4NWF A;  3N84 A;  1SHA A;  3C7I A;  5EG3 B;  2EL8 A;  2Y1M A;  1A1E A;  1JWO A;  1FU5 A;  1CWE A;  1FMK A;  3EAC A;  1R1Q A;  1YVL A;  2MRK A;  5IBS A;  3UF4 A;  3VS6 A;  3N8M A;  4FL2 A;  3MXY A;  1FBV A;  1CWD L;  5EEQ A;  2DLY A;  3CD3 A;  1AYA A;  3VRY A;  2YU7 A;  2IUI A;  1O4K A;  2HDX A;  4F59 A;  3NHN A;  3VS5 A;  1R1P A;  2ECD A;  2RMX A;  1LUM A;  1D1Z A;  1RQQ C;  4XZ0 A;  1BG1 A;  3VS3 A;  1O4R A;  1O48 A;  1O4N A;  2FCI A;  3BKB A;  1O4Q A;  4X6S A;  1RPY A;  3KFJ A;  1SKJ A;  2L4K A;  2ETZ A;  3QWX X;  5GJH A;  2AOB A;  3OVE A;  1HCT B;  1FU6 A;  1O47 A;  3IN7 A;  1JYU A;  2DM0 A;  3CWG A;  1IS0 A;  1H9O A;  3BUM B;  5KAZ A;  1GHU A;  1LUK A;  3S9K A;  1KA7 A;  4QSY A;  1RJA A;  1AD5 A;  2MQI A;  1O49 A;  1AOU F;  1GRI A;  2XP1 A;  4EIH A;  2C0O A;  3QWY A;  3WA4 A;  2PLD A;  1QCF A;  5GJI A;  1O4M A;  3PFV A;  4LUE A;  3VS0 A;  4U1P A;  5DC0 B;  2EU0 A;  1A81 A;  2LQN A;  1NZV A;  2HDV A;  1O4B A;  3OB2 B;  2K79 B;  2B3O A;  1NZL A;  3S8O A;  3VRP A;  1AB2 A;  1Z3K A;  1CSY A;  4JE4 A;  2L3T A;  5I6V A;  1MW4 A;  3VRZ A;  1LCJ A;  2DX0 A;  2H8H A;  2HUW A;  3MAZ A;  2OQ1 A;  4K44 A;  2PLE A;  1O4E A;  1X27 A;  1BLJ A;  2EKX A;  3BUW B;  1BM2 A;  1JYR A;  3IMD A;  1O46 A;  2JYQ A;  5BO4 A;  2DLZ A;  4OHL A;  2K7A B;  2C0I A;  2ROR A;  1FYR A;  2Y1N A;  4E93 A;  4OHI A;  1Y57 A;  3HIZ B;  4DGP A;  3VRQ A;  1ZFP E;  3US4 A;  3VRR A;  5D0J A;  1NRV A;  1A1C A;  4JEG A;  3IN8 A;  1OPL A;  2LCT A;  2CRH A;  1B47 A;  4H1O A;  1A1A A;  4M4Z A;  2KNO A;  4OHH A;  1M61 A;  2SHP A;  3VS2 A;  1X0N A;  3S8L A;  4P9Z A;  2PTK A;  5HKY A;  4DGX A;  2EOB A;  1TZE E;  3UYO A;  1O4D A;  2EYZ A;  1FBZ A;  3VS1 A;  2GE9 A;  3OP0 A;  2PNA A;  2L6K A;  1O4G A;  4K2R A;  3MXC A;  2HMH A;  2LNX A;  3OB1 B;  4F5A A;  1G83 A;  3BUX B;  1SPR A;  1BHF A;  5EHR A;  2OZO A;  2MRJ A;  2VIF A;  4K45 A;  2H46 E;  1O4I A;  3CXL A;  5IBM A;  2HCK A;  1LKK A;  2GSB A;  1I3Z A;  2PNB A;  1X6C A;  1F1W A;  1KC2 A;  2MC1 A;  3EAZ A;  3CBL A;  2ABL A;  4F5B A;  4JGH A;  4TZI A;  5J3X A;  4FBN A;  2EO3 A;  3OV1 A;  1O4F A; 
#chains in the Genus database with same CATH topology
 3N7Y A;  5DC4 A;  3VS4 A;  2AOA A;  1AYB A;  2CIA A;  4NWG A;  1BLK A;  1BHH B;  4E68 A;  1R1S A;  3LYV A;  4EY0 A;  1HCS B;  1D4W A;  3HCK A;  4OHE A;  5EEL A;  1O4J A;  4L1B B;  1UUR A;  1BMB A;  2CI9 A;  1O43 A;  3ZNI A;  4H34 A;  1A07 A;  4ROJ A;  2LQW A;  1AYD A;  4P9V A;  3PLF B;  1SPS A;  1O4A A;  2MK2 A;  3PSK A;  4XZ1 A;  1FHS A;  1CJ1 A;  5HKZ A;  1O42 A;  1CSZ A;  4GL9 E;  1F2F A;  1K9A A;  1P13 A;  2CS0 A;  3PJP A;  1SHD A;  4A4C A;  2RSY A;  2CR4 A;  3TL0 A;  3S8N A;  1A1B A;  2IUG A;  3PS5 A;  1BKL A;  2AUG A;  3TKZ A;  2DCR A;  1O4L A;  2RVF A;  4GPL B;  1D4T A;  3PSJ A;  2EYV A;  1LUN A;  1O45 A;  2C0T A;  2EYY A;  1XA6 A;  4U17 A;  2SRC A;  1JU5 A;  3K2M A;  2EO6 A;  2FO0 A;  1O4C A;  1A08 A;  1OPK A;  1AOT F;  4K11 A;  3T04 A;  3GXX A;  4LUD A;  2H5K A;  4FL3 A;  1PIC A;  5DC9 A;  1KSW A;  4GWF A;  2BBU A;  2Y3A B;  2DVJ A;  1O44 A;  4WWQ A;  1A09 A;  1Y1U A;  3HHM B;  2IZV A;  5AXI A;  5DF6 A;  3IMJ A;  3PQZ A;  2QMS A;  3BUO B;  3VS7 A;  1OO4 A;  1BKM A;  1SHB A;  3M7F A;  2KK6 A;  5AUL A;  1BFJ A;  1LUI A;  1QG1 E;  1OO3 A;  3VGO A;  3VRN A;  5EHP A;  1MIL A;  1BF5 A;  2YSX A;  1WQU A;  3GXW A;  4A4B A;  4D8K A;  2CBL A;  1BFI A;  5CDW A;  1O41 A;  5HKW A;  3BUN B;  3GQI B;  1AYC A;  1TCE A;  1M27 A;  3VRO A;  1YVH A;  1LKL A;  1JYQ A;  1UUS A;  1O4P A;  2CI8 A;  1KA6 A;  2IUH A;  2C9W A;  1O4H A;  4OHD A;  2LNW A;  1QAD A;  1BHH A;  1O4O A;  1IJR A;  1LCK A;  4NWF A;  3N84 A;  1SHA A;  3C7I A;  5EG3 B;  2EL8 A;  2Y1M A;  1A1E A;  1JWO A;  1FU5 A;  1CWE A;  1FMK A;  3EAC A;  1R1Q A;  1YVL A;  2MRK A;  5IBS A;  3UF4 A;  3VS6 A;  3N8M A;  4FL2 A;  3MXY A;  1FBV A;  1CWD L;  5EEQ A;  2DLY A;  3CD3 A;  1AYA A;  3VRY A;  2YU7 A;  2IUI A;  1O4K A;  2HDX A;  4F59 A;  3NHN A;  3VS5 A;  1R1P A;  2ECD A;  2RMX A;  1LUM A;  1D1Z A;  1RQQ C;  4XZ0 A;  1BG1 A;  3VS3 A;  1O4R A;  1O48 A;  1O4N A;  2FCI A;  3BKB A;  1O4Q A;  4X6S A;  1RPY A;  3KFJ A;  1SKJ A;  2L4K A;  2ETZ A;  3QWX X;  5GJH A;  2AOB A;  3OVE A;  1HCT B;  1FU6 A;  1O47 A;  3IN7 A;  1JYU A;  2DM0 A;  3CWG A;  1IS0 A;  1H9O A;  3BUM B;  5KAZ A;  2KGY A;  1GHU A;  1LUK A;  3S9K A;  1KA7 A;  4QSY A;  1RJA A;  1AD5 A;  2MQI A;  1O49 A;  1AOU F;  1GRI A;  2XP1 A;  4EIH A;  2C0O A;  3QWY A;  3WA4 A;  2PLD A;  1QCF A;  5GJI A;  1O4M A;  3PFV A;  4LUE A;  3VS0 A;  4U1P A;  5DC0 B;  3K2T A;  2EU0 A;  1A81 A;  2LQN A;  1NZV A;  2HDV A;  1O4B A;  3OB2 B;  2K79 B;  2B3O A;  1NZL A;  3S8O A;  3VRP A;  1AB2 A;  1Z3K A;  1CSY A;  4JE4 A;  2L3T A;  5I6V A;  1MW4 A;  3VRZ A;  1LCJ A;  2DX0 A;  2H8H A;  2HUW A;  3MAZ A;  2OQ1 A;  4K44 A;  2PLE A;  1O4E A;  1X27 A;  1BLJ A;  2EKX A;  3BUW B;  1BM2 A;  1JYR A;  3IMD A;  1O46 A;  2JYQ A;  5BO4 A;  2DLZ A;  4OHL A;  2K7A B;  2C0I A;  2ROR A;  1FYR A;  2Y1N A;  4E93 A;  4OHI A;  1Y57 A;  3HIZ B;  4DGP A;  3VRQ A;  1ZFP E;  3US4 A;  3VRR A;  5D0J A;  1NRV A;  1A1C A;  4JEG A;  3IN8 A;  1OPL A;  2LCT A;  2CRH A;  1B47 A;  4H1O A;  1A1A A;  4M4Z A;  2KNO A;  4OHH A;  1M61 A;  2SHP A;  3VS2 A;  1X0N A;  3S8L A;  4P9Z A;  2PTK A;  5HKY A;  4DGX A;  2EOB A;  1TZE E;  3UYO A;  1O4D A;  2EYZ A;  1FBZ A;  3VS1 A;  2GE9 A;  3OP0 A;  2PNA A;  2L6K A;  1O4G A;  4K2R A;  3MXC A;  2HMH A;  2LNX A;  3OB1 B;  4F5A A;  1G83 A;  3BUX B;  1SPR A;  1BHF A;  5EHR A;  2OZO A;  2MRJ A;  2VIF A;  4K45 A;  2H46 E;  1O4I A;  3CXL A;  5IBM A;  2HCK A;  1LKK A;  2GSB A;  1I3Z A;  2PNB A;  1X6C A;  2LRA A;  1F1W A;  1KC2 A;  2MC1 A;  3EAZ A;  3CBL A;  2ABL A;  4F5B A;  4JGH A;  4TZI A;  5J3X A;  4FBN A;  2EO3 A;  3OV1 A;  1O4F A; 
#chains in the Genus database with same CATH homology
 3N7Y A;  5DC4 A;  3VS4 A;  2AOA A;  1AYB A;  2CIA A;  4NWG A;  1BLK A;  1BHH B;  4E68 A;  1R1S A;  4EY0 A;  1HCS B;  1D4W A;  3HCK A;  4OHE A;  5EEL A;  1O4J A;  4L1B B;  1UUR A;  1BMB A;  2CI9 A;  1O43 A;  3ZNI A;  4H34 A;  1A07 A;  4ROJ A;  2LQW A;  1AYD A;  4P9V A;  3PLF B;  1SPS A;  1O4A A;  2MK2 A;  3PSK A;  4XZ1 A;  1FHS A;  1CJ1 A;  5HKZ A;  1O42 A;  1CSZ A;  4GL9 E;  1F2F A;  1K9A A;  1P13 A;  2CS0 A;  3PJP A;  1SHD A;  4A4C A;  2RSY A;  2CR4 A;  3TL0 A;  3S8N A;  1A1B A;  2IUG A;  3PS5 A;  1BKL A;  2AUG A;  3TKZ A;  2DCR A;  1O4L A;  2RVF A;  4GPL B;  1D4T A;  3PSJ A;  2EYV A;  1LUN A;  1O45 A;  2C0T A;  2EYY A;  1XA6 A;  4U17 A;  2SRC A;  1JU5 A;  3K2M A;  2EO6 A;  2FO0 A;  1O4C A;  1A08 A;  1OPK A;  1AOT F;  4K11 A;  3T04 A;  3GXX A;  4LUD A;  2H5K A;  4FL3 A;  1PIC A;  5DC9 A;  1KSW A;  4GWF A;  2BBU A;  2Y3A B;  2DVJ A;  1O44 A;  4WWQ A;  1A09 A;  1Y1U A;  3HHM B;  2IZV A;  5AXI A;  5DF6 A;  3IMJ A;  3PQZ A;  2QMS A;  3BUO B;  3VS7 A;  1OO4 A;  1BKM A;  1SHB A;  3M7F A;  2KK6 A;  5AUL A;  1BFJ A;  1LUI A;  1QG1 E;  1OO3 A;  3VGO A;  3VRN A;  5EHP A;  1MIL A;  1BF5 A;  2YSX A;  1WQU A;  3GXW A;  4A4B A;  4D8K A;  2CBL A;  1BFI A;  5CDW A;  1O41 A;  5HKW A;  3BUN B;  3GQI B;  1AYC A;  1TCE A;  1M27 A;  3VRO A;  1YVH A;  1LKL A;  1JYQ A;  1UUS A;  1O4P A;  2CI8 A;  1KA6 A;  2IUH A;  2C9W A;  1O4H A;  4OHD A;  2LNW A;  1QAD A;  1BHH A;  1O4O A;  1IJR A;  1LCK A;  4NWF A;  3N84 A;  1SHA A;  3C7I A;  5EG3 B;  2EL8 A;  2Y1M A;  1A1E A;  1JWO A;  1FU5 A;  1CWE A;  1FMK A;  3EAC A;  1R1Q A;  1YVL A;  2MRK A;  5IBS A;  3UF4 A;  3VS6 A;  3N8M A;  4FL2 A;  3MXY A;  1FBV A;  1CWD L;  5EEQ A;  2DLY A;  3CD3 A;  1AYA A;  3VRY A;  2YU7 A;  2IUI A;  1O4K A;  2HDX A;  4F59 A;  3NHN A;  3VS5 A;  1R1P A;  2ECD A;  2RMX A;  1LUM A;  1D1Z A;  1RQQ C;  4XZ0 A;  1BG1 A;  3VS3 A;  1O4R A;  1O48 A;  1O4N A;  2FCI A;  3BKB A;  1O4Q A;  4X6S A;  1RPY A;  3KFJ A;  1SKJ A;  2L4K A;  2ETZ A;  3QWX X;  5GJH A;  2AOB A;  3OVE A;  1HCT B;  1FU6 A;  1O47 A;  3IN7 A;  1JYU A;  2DM0 A;  3CWG A;  1IS0 A;  1H9O A;  3BUM B;  5KAZ A;  1GHU A;  1LUK A;  3S9K A;  1KA7 A;  4QSY A;  1RJA A;  1AD5 A;  2MQI A;  1O49 A;  1AOU F;  1GRI A;  2XP1 A;  4EIH A;  2C0O A;  3QWY A;  3WA4 A;  2PLD A;  1QCF A;  5GJI A;  1O4M A;  3PFV A;  4LUE A;  3VS0 A;  4U1P A;  5DC0 B;  2EU0 A;  1A81 A;  2LQN A;  1NZV A;  2HDV A;  1O4B A;  3OB2 B;  2K79 B;  2B3O A;  1NZL A;  3S8O A;  3VRP A;  1AB2 A;  1Z3K A;  1CSY A;  4JE4 A;  2L3T A;  5I6V A;  1MW4 A;  3VRZ A;  1LCJ A;  2DX0 A;  2H8H A;  2HUW A;  3MAZ A;  2OQ1 A;  4K44 A;  2PLE A;  1O4E A;  1X27 A;  1BLJ A;  2EKX A;  3BUW B;  1BM2 A;  1JYR A;  3IMD A;  1O46 A;  2JYQ A;  5BO4 A;  2DLZ A;  4OHL A;  2K7A B;  2C0I A;  2ROR A;  1FYR A;  2Y1N A;  4E93 A;  4OHI A;  1Y57 A;  3HIZ B;  4DGP A;  3VRQ A;  1ZFP E;  3US4 A;  3VRR A;  5D0J A;  1NRV A;  1A1C A;  4JEG A;  3IN8 A;  1OPL A;  2LCT A;  2CRH A;  1B47 A;  4H1O A;  1A1A A;  4M4Z A;  2KNO A;  4OHH A;  1M61 A;  2SHP A;  3VS2 A;  1X0N A;  3S8L A;  4P9Z A;  2PTK A;  5HKY A;  4DGX A;  2EOB A;  1TZE E;  3UYO A;  1O4D A;  2EYZ A;  1FBZ A;  3VS1 A;  2GE9 A;  3OP0 A;  2PNA A;  2L6K A;  1O4G A;  4K2R A;  3MXC A;  2HMH A;  2LNX A;  3OB1 B;  4F5A A;  1G83 A;  3BUX B;  1SPR A;  1BHF A;  5EHR A;  2OZO A;  2MRJ A;  2VIF A;  4K45 A;  2H46 E;  1O4I A;  3CXL A;  5IBM A;  2HCK A;  1LKK A;  2GSB A;  1I3Z A;  2PNB A;  1X6C A;  1F1W A;  1KC2 A;  2MC1 A;  3EAZ A;  3CBL A;  2ABL A;  4F5B A;  4JGH A;  4TZI A;  5J3X A;  4FBN A;  2EO3 A;  3OV1 A;  1O4F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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