1O4DA

Crystal structure of sh2 in complex with ru78262.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4dA00
2LQWA 3MAZA 4FBNA 3WA4A 2EYVA 1O4LA 5IBMA 5HKWA 1A1CA 4A4CA 1LUIA 2LNXA 1KA7A 2EO6A 3CXLA 5HKYA 1O46A 3VROA 2Y1NA 2CIAA 4E93A 4OHEA 3GXXA 1NRVA 2JYQA 2K7AB 3VS1A 2AUGA 4NWGA 5DC9A 1D4WA 4TZIA 2AOAA 1BF5A 3GQIB 1BHHA 4QSYA 3VRNA 1RQQC 2B3OA 4P9VA 1YVLA 2C0IA 2PNBA 3PQZA 1F1WA 3UF4A 1O4FA 2L3TA 5BO4A 3CD3A 1CWDL 3ZNIA 1Y57A 2RSYA 2Y1MA 1BLKA 2LQNA 1A1BA 1SHAA 1WQUA 4L1BB 2ECDA 2RVFA 3S8NA 3PLFB 1IJRA 1A08A 4OHIA 1SHBA 1JYRA 3VS4A 3VS0A 3HHMB 1F2FA 1O4BA 1O4MA 1SKJA 2GE9A 2MRJA 1FU5A 1P13A 1NZLA 1AYCA 3HCKA 1CSZA 1K9AA 1BKMA 4DGXA 1AD5A 3QWYA 4P9ZA 4F59A 5I6VA 1M61A 4U1PA 2DLZA 1AOTF 1AOUF 3PS5A 3GXWA 1RJAA 3S8LA 4K11A 1O49A 2CRHA 1Y1UA 3OB2B 3TL0A 1SPRA 1FBZA 1BHFA 1O4GA 1O45A 1O44A 1JWOA 1QADA 2EOBA 3BUOB 4U17A 2ABLA 2VIFA 1LUMA 2L4KA 3OV1A 3VRZA 2YU7A 3EAZA 2GSBA 2DM0A 4OHLA 4A4BA 4EIHA 3BUXB 4GL9E 5IBSA 3N84A 1FU6A 1FYRA 3VS7A 4WWQA 2MRKA 4K2RA 3MXYA 1R1PA 2PLEA 1A07A 3TKZA 2HUWA 3CWGA 2EYYA 2CI9A 3VGOA 3VS2A 1O4KA 3S8OA 1O4EA 2RMXA 4GPLB 3PFVA 3QWXX 1O4PA 5DF6A 1ZFPE 1TCEA 2OZOA 3US4A 4DGPA 1O4HA 4E68A 2AOBA 2IZVA 1HCSB 1H9OA 1JYUA 2H5KA 2QMSA 5D0JA 2DVJA 3C7IA 1BLJA 1LCJA 1G83A 1UURA 1UUSA 1OPKA 3CBLA 3MXCA 4GWFA 4OHDA 4JGHA 3VRPA 5GJIA 2EYZA 3IN8A 1I3ZA 2DX0A 1YVHA 2ETZA 4F5BA 1SPSA 3N8MA 1GRIA 5EHRA 2EKXA 5J3XA 4M4ZA 2PLDA 3HIZB 3S9KA 1O4QA 3T04A 3BKBA 1BFIA 1OPLA 2CBLA 1A81A 1AYBA 5DC4A 1A09A 4EY0A 2PTKA 2LCTA 1OO4A 2IUIA 1O4DA 2MQIA 1BM2A 1SHDA 1MW4A 1FHSA 1FBVA 2EU0A 1QG1E 1B47A 4X6SA 1O4NA 1D4TA 2DLYA 5EHPA 1O48A 1X27A 4JE4A 5DC0B 3BUWB 3BUMB 3OB1B 2RORA 1IS0A 1XA6A 1KC2A 4F5AA 1M27A 1KSWA 2YSXA 2C0OA 1HCTB 1O41A 1O43A 2C0TA 2HDVA 3VS6A 1AYDA 1AYAA 4D8KA 3VS3A 1JYQA 1CSYA 2L6KA 5EG3B 3N7YA 1O4OA 3IN7A 2HMHA 1RPYA 1TZEE 1LKKA 1AB2A 1O4JA 2CR4A 4XZ1A 2KNOA 3KFJA 1X0NA 1CWEA 3VRQA 5AULA 1LKLA 2PNAA 2XP1A 3NHNA 4JEGA 1BHHB 1KA6A 1NZVA 4FL3A 1LUNA 3K2MA 1GHUA 4LUDA 1O47A 5GJHA 5AXIA 1D1ZA 4XZ0A 3OP0A 2KK6A 1MILA 2EL8A 1A1EA 3IMJA 4OHHA 5HKZA 2H8HA 3VS5A 4ROJA 3BUNB 4LUEA 1A1AA 2CS0A 1QCFA 2MK2A 2Y3AB 1O4RA 2IUGA 1BKLA 4H1OA 2EO3A 2CI8A 5CDWA 3UYOA 1CJ1A 2DCRA 1LCKA 2C9WA 3IMDA 1PICA 4NWFA 2SRCA 5EEQA 2LNWA 3VRRA 3PSKA 1X6CA 3M7FA 3VRYA 1R1SA 2FO0A 2BBUA 2K79B 1OO3A 2HCKA 1BFJA 2MC1A 4H34A 2HDXA 1O4IA 4K44A 3OVEA 1R1QA 4FL2A 1LUKA 3PJPA 5EELA 1BMBA 3EACA 2IUHA 1BG1A 5KAZA 1JU5A 1Z3KA 1O42A 1FMKA 1O4CA 2OQ1A 3PSJA 2FCIA 2H46E 1O4AA 4K45A 2SHPA
chains in the Genus database with same CATH superfamily
2LQWA 3MAZA 4FBNA 3WA4A 2EYVA 1O4LA 5IBMA 5HKWA 1A1CA 4A4CA 1LUIA 2LNXA 1KA7A 2EO6A 3CXLA 5HKYA 1O46A 3VROA 2Y1NA 2CIAA 4E93A 4OHEA 3GXXA 1NRVA 2JYQA 2K7AB 3VS1A 2AUGA 4NWGA 5DC9A 1D4WA 4TZIA 2AOAA 1BF5A 3GQIB 1BHHA 4QSYA 3VRNA 1RQQC 2B3OA 4P9VA 1YVLA 2C0IA 2PNBA 3PQZA 1F1WA 3UF4A 3K2TA 1O4FA 2L3TA 5BO4A 3CD3A 1CWDL 3ZNIA 1Y57A 2RSYA 2Y1MA 1BLKA 2LQNA 1A1BA 1SHAA 1WQUA 4L1BB 2ECDA 2RVFA 3S8NA 3PLFB 1IJRA 1A08A 4OHIA 1SHBA 1JYRA 3VS4A 3VS0A 3HHMB 1F2FA 1O4BA 1O4MA 1SKJA 2GE9A 2MRJA 1FU5A 1P13A 1NZLA 1AYCA 3HCKA 1CSZA 1K9AA 1BKMA 4DGXA 1AD5A 3QWYA 4P9ZA 4F59A 5I6VA 1M61A 4U1PA 2DLZA 1AOTF 1AOUF 3PS5A 3GXWA 1RJAA 3S8LA 4K11A 1O49A 2CRHA 1Y1UA 3OB2B 3TL0A 1SPRA 1FBZA 1BHFA 1O4GA 1O45A 1O44A 1JWOA 1QADA 2EOBA 3BUOB 4U17A 2ABLA 2VIFA 1LUMA 2L4KA 3OV1A 3VRZA 2YU7A 3EAZA 2GSBA 2DM0A 4OHLA 4A4BA 4EIHA 3BUXB 4GL9E 5IBSA 3N84A 1FU6A 1FYRA 3VS7A 4WWQA 2MRKA 4K2RA 3MXYA 1R1PA 2PLEA 1A07A 3TKZA 2HUWA 3CWGA 2EYYA 2CI9A 3VGOA 3VS2A 1O4KA 3S8OA 1O4EA 2RMXA 4GPLB 3PFVA 3QWXX 1O4PA 5DF6A 1ZFPE 1TCEA 2OZOA 3US4A 4DGPA 1O4HA 4E68A 2AOBA 2IZVA 1HCSB 1H9OA 1JYUA 2H5KA 2KGYA 2QMSA 5D0JA 2DVJA 3C7IA 1BLJA 1LCJA 1G83A 1UURA 1UUSA 1OPKA 3CBLA 3MXCA 4GWFA 4OHDA 4JGHA 3VRPA 5GJIA 2EYZA 3IN8A 1I3ZA 2DX0A 1YVHA 2ETZA 3LYVA 4F5BA 1SPSA 3N8MA 1GRIA 5EHRA 2EKXA 5J3XA 4M4ZA 2PLDA 3HIZB 3S9KA 1O4QA 3T04A 3BKBA 1BFIA 1OPLA 2CBLA 1A81A 1AYBA 5DC4A 1A09A 4EY0A 2PTKA 2LCTA 1OO4A 2IUIA 1O4DA 2MQIA 1BM2A 1SHDA 1MW4A 1FHSA 1FBVA 2EU0A 1QG1E 1B47A 4X6SA 1O4NA 1D4TA 2DLYA 5EHPA 1O48A 1X27A 4JE4A 5DC0B 3BUWB 3BUMB 3OB1B 2RORA 1IS0A 1XA6A 1KC2A 4F5AA 1M27A 1KSWA 2YSXA 2C0OA 1HCTB 1O41A 1O43A 2C0TA 2HDVA 3VS6A 1AYDA 1AYAA 4D8KA 3VS3A 1JYQA 1CSYA 2L6KA 5EG3B 3N7YA 1O4OA 3IN7A 2HMHA 1RPYA 1TZEE 1LKKA 1AB2A 1O4JA 2CR4A 4XZ1A 2KNOA 3KFJA 1X0NA 1CWEA 3VRQA 2LRAA 5AULA 1LKLA 2PNAA 2XP1A 3NHNA 4JEGA 1BHHB 1KA6A 1NZVA 4FL3A 1LUNA 3K2MA 1GHUA 4LUDA 1O47A 5GJHA 5AXIA 1D1ZA 4XZ0A 3OP0A 2KK6A 1MILA 2EL8A 1A1EA 3IMJA 4OHHA 5HKZA 2H8HA 3VS5A 4ROJA 3BUNB 4LUEA 1A1AA 2CS0A 1QCFA 2MK2A 2Y3AB 1O4RA 2IUGA 1BKLA 4H1OA 2EO3A 2CI8A 5CDWA 3UYOA 1CJ1A 2DCRA 1LCKA 2C9WA 3IMDA 1PICA 4NWFA 2SRCA 5EEQA 2LNWA 3VRRA 3PSKA 1X6CA 3M7FA 3VRYA 1R1SA 2FO0A 2BBUA 2K79B 1OO3A 2HCKA 1BFJA 2MC1A 4H34A 2HDXA 1O4IA 4K44A 3OVEA 1R1QA 4FL2A 1LUKA 3PJPA 5EELA 1BMBA 3EACA 2IUHA 1BG1A 5KAZA 1JU5A 1Z3KA 1O42A 1FMKA 1O4CA 2OQ1A 3PSJA 2FCIA 2H46E 1O4AA 4K45A 2SHPA
chains in the Genus database with same CATH topology
2LQWA 3MAZA 4FBNA 3WA4A 2EYVA 1O4LA 5IBMA 5HKWA 1A1CA 4A4CA 1LUIA 2LNXA 1KA7A 2EO6A 3CXLA 5HKYA 1O46A 3VROA 2Y1NA 2CIAA 4E93A 4OHEA 3GXXA 1NRVA 2JYQA 2K7AB 3VS1A 2AUGA 4NWGA 5DC9A 1D4WA 4TZIA 2AOAA 1BF5A 3GQIB 1BHHA 4QSYA 3VRNA 1RQQC 2B3OA 4P9VA 1YVLA 2C0IA 2PNBA 3PQZA 1F1WA 3UF4A 1O4FA 2L3TA 5BO4A 3CD3A 1CWDL 3ZNIA 1Y57A 2RSYA 2Y1MA 1BLKA 2LQNA 1A1BA 1SHAA 1WQUA 4L1BB 2ECDA 2RVFA 3S8NA 3PLFB 1IJRA 1A08A 4OHIA 1SHBA 1JYRA 3VS4A 3VS0A 3HHMB 1F2FA 1O4BA 1O4MA 1SKJA 2GE9A 2MRJA 1FU5A 1P13A 1NZLA 1AYCA 3HCKA 1CSZA 1K9AA 1BKMA 4DGXA 1AD5A 3QWYA 4P9ZA 4F59A 5I6VA 1M61A 4U1PA 2DLZA 1AOTF 1AOUF 3PS5A 3GXWA 1RJAA 3S8LA 4K11A 1O49A 2CRHA 1Y1UA 3OB2B 3TL0A 1SPRA 1FBZA 1BHFA 1O4GA 1O45A 1O44A 1JWOA 1QADA 2EOBA 3BUOB 4U17A 2ABLA 2VIFA 1LUMA 2L4KA 3OV1A 3VRZA 2YU7A 3EAZA 2GSBA 2DM0A 4OHLA 4A4BA 4EIHA 3BUXB 4GL9E 5IBSA 3N84A 1FU6A 1FYRA 3VS7A 4WWQA 2MRKA 4K2RA 3MXYA 1R1PA 2PLEA 1A07A 3TKZA 2HUWA 3CWGA 2EYYA 2CI9A 3VGOA 3VS2A 1O4KA 3S8OA 1O4EA 2RMXA 4GPLB 3PFVA 3QWXX 1O4PA 5DF6A 1ZFPE 1TCEA 2OZOA 3US4A 4DGPA 1O4HA 4E68A 2AOBA 2IZVA 1HCSB 1H9OA 1JYUA 2H5KA 2QMSA 5D0JA 2DVJA 3C7IA 1BLJA 1LCJA 1G83A 1UURA 1UUSA 1OPKA 3CBLA 3MXCA 4GWFA 4OHDA 4JGHA 3VRPA 5GJIA 2EYZA 3IN8A 1I3ZA 2DX0A 1YVHA 2ETZA 4F5BA 1SPSA 3N8MA 1GRIA 5EHRA 2EKXA 5J3XA 4M4ZA 2PLDA 3HIZB 3S9KA 1O4QA 3T04A 3BKBA 1BFIA 1OPLA 2CBLA 1A81A 1AYBA 5DC4A 1A09A 4EY0A 2PTKA 2LCTA 1OO4A 2IUIA 1O4DA 2MQIA 1BM2A 1SHDA 1MW4A 1FHSA 1FBVA 2EU0A 1QG1E 1B47A 4X6SA 1O4NA 1D4TA 2DLYA 5EHPA 1O48A 1X27A 4JE4A 5DC0B 3BUWB 3BUMB 3OB1B 2RORA 1IS0A 1XA6A 1KC2A 4F5AA 1M27A 1KSWA 2YSXA 2C0OA 1HCTB 1O41A 1O43A 2C0TA 2HDVA 3VS6A 1AYDA 1AYAA 4D8KA 3VS3A 1JYQA 1CSYA 2L6KA 5EG3B 3N7YA 1O4OA 3IN7A 2HMHA 1RPYA 1TZEE 1LKKA 1AB2A 1O4JA 2CR4A 4XZ1A 2KNOA 3KFJA 1X0NA 1CWEA 3VRQA 5AULA 1LKLA 2PNAA 2XP1A 3NHNA 4JEGA 1BHHB 1KA6A 1NZVA 4FL3A 1LUNA 3K2MA 1GHUA 4LUDA 1O47A 5GJHA 5AXIA 1D1ZA 4XZ0A 3OP0A 2KK6A 1MILA 2EL8A 1A1EA 3IMJA 4OHHA 5HKZA 2H8HA 3VS5A 4ROJA 3BUNB 4LUEA 1A1AA 2CS0A 1QCFA 2MK2A 2Y3AB 1O4RA 2IUGA 1BKLA 4H1OA 2EO3A 2CI8A 5CDWA 3UYOA 1CJ1A 2DCRA 1LCKA 2C9WA 3IMDA 1PICA 4NWFA 2SRCA 5EEQA 2LNWA 3VRRA 3PSKA 1X6CA 3M7FA 3VRYA 1R1SA 2FO0A 2BBUA 2K79B 1OO3A 2HCKA 1BFJA 2MC1A 4H34A 2HDXA 1O4IA 4K44A 3OVEA 1R1QA 4FL2A 1LUKA 3PJPA 5EELA 1BMBA 3EACA 2IUHA 1BG1A 5KAZA 1JU5A 1Z3KA 1O42A 1FMKA 1O4CA 2OQ1A 3PSJA 2FCIA 2H46E 1O4AA 4K45A 2SHPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LQW A;  3MAZ A;  4FBN A;  3WA4 A;  2EYV A;  1O4L A;  5IBM A;  5HKW A;  1A1C A;  4A4C A;  1LUI A;  2LNX A;  1KA7 A;  2EO6 A;  3CXL A;  5HKY A;  1O46 A;  3VRO A;  2Y1N A;  2CIA A;  4E93 A;  4OHE A;  3GXX A;  1NRV A;  2JYQ A;  2K7A B;  3VS1 A;  2AUG A;  4NWG A;  5DC9 A;  1D4W A;  4TZI A;  2AOA A;  1BF5 A;  3GQI B;  1BHH A;  4QSY A;  3VRN A;  1RQQ C;  2B3O A;  4P9V A;  1YVL A;  2C0I A;  2PNB A;  3PQZ A;  1F1W A;  3UF4 A;  1O4F A;  2L3T A;  5BO4 A;  3CD3 A;  1CWD L;  3ZNI A;  1Y57 A;  2RSY A;  2Y1M A;  1BLK A;  2LQN A;  1A1B A;  1SHA A;  1WQU A;  4L1B B;  2ECD A;  2RVF A;  3S8N A;  3PLF B;  1IJR A;  1A08 A;  4OHI A;  1SHB A;  1JYR A;  3VS4 A;  3VS0 A;  3HHM B;  1F2F A;  1O4B A;  1O4M A;  1SKJ A;  2GE9 A;  2MRJ A;  1FU5 A;  1P13 A;  1NZL A;  1AYC A;  3HCK A;  1CSZ A;  1K9A A;  1BKM A;  4DGX A;  1AD5 A;  3QWY A;  4P9Z A;  4F59 A;  5I6V A;  1M61 A;  4U1P A;  2DLZ A;  1AOT F;  1AOU F;  3PS5 A;  3GXW A;  1RJA A;  3S8L A;  4K11 A;  1O49 A;  2CRH A;  1Y1U A;  3OB2 B;  3TL0 A;  1SPR A;  1FBZ A;  1BHF A;  1O4G A;  1O45 A;  1O44 A;  1JWO A;  1QAD A;  2EOB A;  3BUO B;  4U17 A;  2ABL A;  2VIF A;  1LUM A;  2L4K A;  3OV1 A;  3VRZ A;  2YU7 A;  3EAZ A;  2GSB A;  2DM0 A;  4OHL A;  4A4B A;  4EIH A;  3BUX B;  4GL9 E;  5IBS A;  3N84 A;  1FU6 A;  1FYR A;  3VS7 A;  4WWQ A;  2MRK A;  4K2R A;  3MXY A;  1R1P A;  2PLE A;  1A07 A;  3TKZ A;  2HUW A;  3CWG A;  2EYY A;  2CI9 A;  3VGO A;  3VS2 A;  1O4K A;  3S8O A;  1O4E A;  2RMX A;  4GPL B;  3PFV A;  3QWX X;  1O4P A;  5DF6 A;  1ZFP E;  1TCE A;  2OZO A;  3US4 A;  4DGP A;  1O4H A;  4E68 A;  2AOB A;  2IZV A;  1HCS B;  1H9O A;  1JYU A;  2H5K A;  2QMS A;  5D0J A;  2DVJ A;  3C7I A;  1BLJ A;  1LCJ A;  1G83 A;  1UUR A;  1UUS A;  1OPK A;  3CBL A;  3MXC A;  4GWF A;  4OHD A;  4JGH A;  3VRP A;  5GJI A;  2EYZ A;  3IN8 A;  1I3Z A;  2DX0 A;  1YVH A;  2ETZ A;  4F5B A;  1SPS A;  3N8M A;  1GRI A;  5EHR A;  2EKX A;  5J3X A;  4M4Z A;  2PLD A;  3HIZ B;  3S9K A;  1O4Q A;  3T04 A;  3BKB A;  1BFI A;  1OPL A;  2CBL A;  1A81 A;  1AYB A;  5DC4 A;  1A09 A;  4EY0 A;  2PTK A;  2LCT A;  1OO4 A;  2IUI A;  1O4D A;  2MQI A;  1BM2 A;  1SHD A;  1MW4 A;  1FHS A;  1FBV A;  2EU0 A;  1QG1 E;  1B47 A;  4X6S A;  1O4N A;  1D4T A;  2DLY A;  5EHP A;  1O48 A;  1X27 A;  4JE4 A;  5DC0 B;  3BUW B;  3BUM B;  3OB1 B;  2ROR A;  1IS0 A;  1XA6 A;  1KC2 A;  4F5A A;  1M27 A;  1KSW A;  2YSX A;  2C0O A;  1HCT B;  1O41 A;  1O43 A;  2C0T A;  2HDV A;  3VS6 A;  1AYD A;  1AYA A;  4D8K A;  3VS3 A;  1JYQ A;  1CSY A;  2L6K A;  5EG3 B;  3N7Y A;  1O4O A;  3IN7 A;  2HMH A;  1RPY A;  1TZE E;  1LKK A;  1AB2 A;  1O4J A;  2CR4 A;  4XZ1 A;  2KNO A;  3KFJ A;  1X0N A;  1CWE A;  3VRQ A;  5AUL A;  1LKL A;  2PNA A;  2XP1 A;  3NHN A;  4JEG A;  1BHH B;  1KA6 A;  1NZV A;  4FL3 A;  1LUN A;  3K2M A;  1GHU A;  4LUD A;  1O47 A;  5GJH A;  5AXI A;  1D1Z A;  4XZ0 A;  3OP0 A;  2KK6 A;  1MIL A;  2EL8 A;  1A1E A;  3IMJ A;  4OHH A;  5HKZ A;  2H8H A;  3VS5 A;  4ROJ A;  3BUN B;  4LUE A;  1A1A A;  2CS0 A;  1QCF A;  2MK2 A;  2Y3A B;  1O4R A;  2IUG A;  1BKL A;  4H1O A;  2EO3 A;  2CI8 A;  5CDW A;  3UYO A;  1CJ1 A;  2DCR A;  1LCK A;  2C9W A;  3IMD A;  1PIC A;  4NWF A;  2SRC A;  5EEQ A;  2LNW A;  3VRR A;  3PSK A;  1X6C A;  3M7F A;  3VRY A;  1R1S A;  2FO0 A;  2BBU A;  2K79 B;  1OO3 A;  2HCK A;  1BFJ A;  2MC1 A;  4H34 A;  2HDX A;  1O4I A;  4K44 A;  3OVE A;  1R1Q A;  4FL2 A;  1LUK A;  3PJP A;  5EEL A;  1BMB A;  3EAC A;  2IUH A;  1BG1 A;  5KAZ A;  1JU5 A;  1Z3K A;  1O42 A;  1FMK A;  1O4C A;  2OQ1 A;  3PSJ A;  2FCI A;  2H46 E;  1O4A A;  4K45 A;  2SHP A; 
#chains in the Genus database with same CATH topology
 2LQW A;  3MAZ A;  4FBN A;  3WA4 A;  2EYV A;  1O4L A;  5IBM A;  5HKW A;  1A1C A;  4A4C A;  1LUI A;  2LNX A;  1KA7 A;  2EO6 A;  3CXL A;  5HKY A;  1O46 A;  3VRO A;  2Y1N A;  2CIA A;  4E93 A;  4OHE A;  3GXX A;  1NRV A;  2JYQ A;  2K7A B;  3VS1 A;  2AUG A;  4NWG A;  5DC9 A;  1D4W A;  4TZI A;  2AOA A;  1BF5 A;  3GQI B;  1BHH A;  4QSY A;  3VRN A;  1RQQ C;  2B3O A;  4P9V A;  1YVL A;  2C0I A;  2PNB A;  3PQZ A;  1F1W A;  3UF4 A;  3K2T A;  1O4F A;  2L3T A;  5BO4 A;  3CD3 A;  1CWD L;  3ZNI A;  1Y57 A;  2RSY A;  2Y1M A;  1BLK A;  2LQN A;  1A1B A;  1SHA A;  1WQU A;  4L1B B;  2ECD A;  2RVF A;  3S8N A;  3PLF B;  1IJR A;  1A08 A;  4OHI A;  1SHB A;  1JYR A;  3VS4 A;  3VS0 A;  3HHM B;  1F2F A;  1O4B A;  1O4M A;  1SKJ A;  2GE9 A;  2MRJ A;  1FU5 A;  1P13 A;  1NZL A;  1AYC A;  3HCK A;  1CSZ A;  1K9A A;  1BKM A;  4DGX A;  1AD5 A;  3QWY A;  4P9Z A;  4F59 A;  5I6V A;  1M61 A;  4U1P A;  2DLZ A;  1AOT F;  1AOU F;  3PS5 A;  3GXW A;  1RJA A;  3S8L A;  4K11 A;  1O49 A;  2CRH A;  1Y1U A;  3OB2 B;  3TL0 A;  1SPR A;  1FBZ A;  1BHF A;  1O4G A;  1O45 A;  1O44 A;  1JWO A;  1QAD A;  2EOB A;  3BUO B;  4U17 A;  2ABL A;  2VIF A;  1LUM A;  2L4K A;  3OV1 A;  3VRZ A;  2YU7 A;  3EAZ A;  2GSB A;  2DM0 A;  4OHL A;  4A4B A;  4EIH A;  3BUX B;  4GL9 E;  5IBS A;  3N84 A;  1FU6 A;  1FYR A;  3VS7 A;  4WWQ A;  2MRK A;  4K2R A;  3MXY A;  1R1P A;  2PLE A;  1A07 A;  3TKZ A;  2HUW A;  3CWG A;  2EYY A;  2CI9 A;  3VGO A;  3VS2 A;  1O4K A;  3S8O A;  1O4E A;  2RMX A;  4GPL B;  3PFV A;  3QWX X;  1O4P A;  5DF6 A;  1ZFP E;  1TCE A;  2OZO A;  3US4 A;  4DGP A;  1O4H A;  4E68 A;  2AOB A;  2IZV A;  1HCS B;  1H9O A;  1JYU A;  2H5K A;  2KGY A;  2QMS A;  5D0J A;  2DVJ A;  3C7I A;  1BLJ A;  1LCJ A;  1G83 A;  1UUR A;  1UUS A;  1OPK A;  3CBL A;  3MXC A;  4GWF A;  4OHD A;  4JGH A;  3VRP A;  5GJI A;  2EYZ A;  3IN8 A;  1I3Z A;  2DX0 A;  1YVH A;  2ETZ A;  3LYV A;  4F5B A;  1SPS A;  3N8M A;  1GRI A;  5EHR A;  2EKX A;  5J3X A;  4M4Z A;  2PLD A;  3HIZ B;  3S9K A;  1O4Q A;  3T04 A;  3BKB A;  1BFI A;  1OPL A;  2CBL A;  1A81 A;  1AYB A;  5DC4 A;  1A09 A;  4EY0 A;  2PTK A;  2LCT A;  1OO4 A;  2IUI A;  1O4D A;  2MQI A;  1BM2 A;  1SHD A;  1MW4 A;  1FHS A;  1FBV A;  2EU0 A;  1QG1 E;  1B47 A;  4X6S A;  1O4N A;  1D4T A;  2DLY A;  5EHP A;  1O48 A;  1X27 A;  4JE4 A;  5DC0 B;  3BUW B;  3BUM B;  3OB1 B;  2ROR A;  1IS0 A;  1XA6 A;  1KC2 A;  4F5A A;  1M27 A;  1KSW A;  2YSX A;  2C0O A;  1HCT B;  1O41 A;  1O43 A;  2C0T A;  2HDV A;  3VS6 A;  1AYD A;  1AYA A;  4D8K A;  3VS3 A;  1JYQ A;  1CSY A;  2L6K A;  5EG3 B;  3N7Y A;  1O4O A;  3IN7 A;  2HMH A;  1RPY A;  1TZE E;  1LKK A;  1AB2 A;  1O4J A;  2CR4 A;  4XZ1 A;  2KNO A;  3KFJ A;  1X0N A;  1CWE A;  3VRQ A;  2LRA A;  5AUL A;  1LKL A;  2PNA A;  2XP1 A;  3NHN A;  4JEG A;  1BHH B;  1KA6 A;  1NZV A;  4FL3 A;  1LUN A;  3K2M A;  1GHU A;  4LUD A;  1O47 A;  5GJH A;  5AXI A;  1D1Z A;  4XZ0 A;  3OP0 A;  2KK6 A;  1MIL A;  2EL8 A;  1A1E A;  3IMJ A;  4OHH A;  5HKZ A;  2H8H A;  3VS5 A;  4ROJ A;  3BUN B;  4LUE A;  1A1A A;  2CS0 A;  1QCF A;  2MK2 A;  2Y3A B;  1O4R A;  2IUG A;  1BKL A;  4H1O A;  2EO3 A;  2CI8 A;  5CDW A;  3UYO A;  1CJ1 A;  2DCR A;  1LCK A;  2C9W A;  3IMD A;  1PIC A;  4NWF A;  2SRC A;  5EEQ A;  2LNW A;  3VRR A;  3PSK A;  1X6C A;  3M7F A;  3VRY A;  1R1S A;  2FO0 A;  2BBU A;  2K79 B;  1OO3 A;  2HCK A;  1BFJ A;  2MC1 A;  4H34 A;  2HDX A;  1O4I A;  4K44 A;  3OVE A;  1R1Q A;  4FL2 A;  1LUK A;  3PJP A;  5EEL A;  1BMB A;  3EAC A;  2IUH A;  1BG1 A;  5KAZ A;  1JU5 A;  1Z3K A;  1O42 A;  1FMK A;  1O4C A;  2OQ1 A;  3PSJ A;  2FCI A;  2H46 E;  1O4A A;  4K45 A;  2SHP A; 
#chains in the Genus database with same CATH homology
 2LQW A;  3MAZ A;  4FBN A;  3WA4 A;  2EYV A;  1O4L A;  5IBM A;  5HKW A;  1A1C A;  4A4C A;  1LUI A;  2LNX A;  1KA7 A;  2EO6 A;  3CXL A;  5HKY A;  1O46 A;  3VRO A;  2Y1N A;  2CIA A;  4E93 A;  4OHE A;  3GXX A;  1NRV A;  2JYQ A;  2K7A B;  3VS1 A;  2AUG A;  4NWG A;  5DC9 A;  1D4W A;  4TZI A;  2AOA A;  1BF5 A;  3GQI B;  1BHH A;  4QSY A;  3VRN A;  1RQQ C;  2B3O A;  4P9V A;  1YVL A;  2C0I A;  2PNB A;  3PQZ A;  1F1W A;  3UF4 A;  1O4F A;  2L3T A;  5BO4 A;  3CD3 A;  1CWD L;  3ZNI A;  1Y57 A;  2RSY A;  2Y1M A;  1BLK A;  2LQN A;  1A1B A;  1SHA A;  1WQU A;  4L1B B;  2ECD A;  2RVF A;  3S8N A;  3PLF B;  1IJR A;  1A08 A;  4OHI A;  1SHB A;  1JYR A;  3VS4 A;  3VS0 A;  3HHM B;  1F2F A;  1O4B A;  1O4M A;  1SKJ A;  2GE9 A;  2MRJ A;  1FU5 A;  1P13 A;  1NZL A;  1AYC A;  3HCK A;  1CSZ A;  1K9A A;  1BKM A;  4DGX A;  1AD5 A;  3QWY A;  4P9Z A;  4F59 A;  5I6V A;  1M61 A;  4U1P A;  2DLZ A;  1AOT F;  1AOU F;  3PS5 A;  3GXW A;  1RJA A;  3S8L A;  4K11 A;  1O49 A;  2CRH A;  1Y1U A;  3OB2 B;  3TL0 A;  1SPR A;  1FBZ A;  1BHF A;  1O4G A;  1O45 A;  1O44 A;  1JWO A;  1QAD A;  2EOB A;  3BUO B;  4U17 A;  2ABL A;  2VIF A;  1LUM A;  2L4K A;  3OV1 A;  3VRZ A;  2YU7 A;  3EAZ A;  2GSB A;  2DM0 A;  4OHL A;  4A4B A;  4EIH A;  3BUX B;  4GL9 E;  5IBS A;  3N84 A;  1FU6 A;  1FYR A;  3VS7 A;  4WWQ A;  2MRK A;  4K2R A;  3MXY A;  1R1P A;  2PLE A;  1A07 A;  3TKZ A;  2HUW A;  3CWG A;  2EYY A;  2CI9 A;  3VGO A;  3VS2 A;  1O4K A;  3S8O A;  1O4E A;  2RMX A;  4GPL B;  3PFV A;  3QWX X;  1O4P A;  5DF6 A;  1ZFP E;  1TCE A;  2OZO A;  3US4 A;  4DGP A;  1O4H A;  4E68 A;  2AOB A;  2IZV A;  1HCS B;  1H9O A;  1JYU A;  2H5K A;  2QMS A;  5D0J A;  2DVJ A;  3C7I A;  1BLJ A;  1LCJ A;  1G83 A;  1UUR A;  1UUS A;  1OPK A;  3CBL A;  3MXC A;  4GWF A;  4OHD A;  4JGH A;  3VRP A;  5GJI A;  2EYZ A;  3IN8 A;  1I3Z A;  2DX0 A;  1YVH A;  2ETZ A;  4F5B A;  1SPS A;  3N8M A;  1GRI A;  5EHR A;  2EKX A;  5J3X A;  4M4Z A;  2PLD A;  3HIZ B;  3S9K A;  1O4Q A;  3T04 A;  3BKB A;  1BFI A;  1OPL A;  2CBL A;  1A81 A;  1AYB A;  5DC4 A;  1A09 A;  4EY0 A;  2PTK A;  2LCT A;  1OO4 A;  2IUI A;  1O4D A;  2MQI A;  1BM2 A;  1SHD A;  1MW4 A;  1FHS A;  1FBV A;  2EU0 A;  1QG1 E;  1B47 A;  4X6S A;  1O4N A;  1D4T A;  2DLY A;  5EHP A;  1O48 A;  1X27 A;  4JE4 A;  5DC0 B;  3BUW B;  3BUM B;  3OB1 B;  2ROR A;  1IS0 A;  1XA6 A;  1KC2 A;  4F5A A;  1M27 A;  1KSW A;  2YSX A;  2C0O A;  1HCT B;  1O41 A;  1O43 A;  2C0T A;  2HDV A;  3VS6 A;  1AYD A;  1AYA A;  4D8K A;  3VS3 A;  1JYQ A;  1CSY A;  2L6K A;  5EG3 B;  3N7Y A;  1O4O A;  3IN7 A;  2HMH A;  1RPY A;  1TZE E;  1LKK A;  1AB2 A;  1O4J A;  2CR4 A;  4XZ1 A;  2KNO A;  3KFJ A;  1X0N A;  1CWE A;  3VRQ A;  5AUL A;  1LKL A;  2PNA A;  2XP1 A;  3NHN A;  4JEG A;  1BHH B;  1KA6 A;  1NZV A;  4FL3 A;  1LUN A;  3K2M A;  1GHU A;  4LUD A;  1O47 A;  5GJH A;  5AXI A;  1D1Z A;  4XZ0 A;  3OP0 A;  2KK6 A;  1MIL A;  2EL8 A;  1A1E A;  3IMJ A;  4OHH A;  5HKZ A;  2H8H A;  3VS5 A;  4ROJ A;  3BUN B;  4LUE A;  1A1A A;  2CS0 A;  1QCF A;  2MK2 A;  2Y3A B;  1O4R A;  2IUG A;  1BKL A;  4H1O A;  2EO3 A;  2CI8 A;  5CDW A;  3UYO A;  1CJ1 A;  2DCR A;  1LCK A;  2C9W A;  3IMD A;  1PIC A;  4NWF A;  2SRC A;  5EEQ A;  2LNW A;  3VRR A;  3PSK A;  1X6C A;  3M7F A;  3VRY A;  1R1S A;  2FO0 A;  2BBU A;  2K79 B;  1OO3 A;  2HCK A;  1BFJ A;  2MC1 A;  4H34 A;  2HDX A;  1O4I A;  4K44 A;  3OVE A;  1R1Q A;  4FL2 A;  1LUK A;  3PJP A;  5EEL A;  1BMB A;  3EAC A;  2IUH A;  1BG1 A;  5KAZ A;  1JU5 A;  1Z3K A;  1O42 A;  1FMK A;  1O4C A;  2OQ1 A;  3PSJ A;  2FCI A;  2H46 E;  1O4A A;  4K45 A;  2SHP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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