1O4FA

Crystal structure of sh2 in complex with ru79073.
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
105
structure length
104
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 25
structure length 104
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4fA00
3T04A 4K44A 5EELA 4EIHA 2EOBA 4EY0A 3IMDA 2EO3A 2PNBA 2L3TA 1JWOA 1AOUF 1OO4A 3CWGA 2HDXA 2EU0A 3VS5A 1A09A 2EYYA 4P9VA 1LCJA 3HHMB 3VRNA 1M61A 2PLDA 1NRVA 4D8KA 4FBNA 3EAZA 2IUGA 4F5AA 2VIFA 1BKMA 1O4EA 5EHRA 3VS3A 2ABLA 2OZOA 1BLJA 2Y1NA 2K7AB 2IUHA 2LQNA 3OVEA 5DC0B 3N7YA 1BMBA 2DCRA 1O4IA 4LUDA 4GPLB 1B47A 1D1ZA 2LQWA 2B3OA 1O49A 3M7FA 2MRKA 2C0IA 1IJRA 1O4LA 3IN8A 1LUNA 3QWXX 2SRCA 1TCEA 1H9OA 3GXXA 4OHDA 1O44A 3PLFB 4K2RA 2MQIA 2GSBA 2CI9A 1O4BA 3EACA 1NZVA 1QG1E 1JU5A 4E93A 2MRJA 1I3ZA 3UF4A 5CDWA 3S8LA 1CSYA 3VS7A 2Y1MA 1O4JA 1O47A 1SPRA 4A4BA 1BFIA 1O4QA 3WA4A 2ECDA 1SHBA 1FBVA 1SKJA 1FHSA 2KNOA 5EEQA 3K2MA 3MAZA 3OB1B 2MC1A 1BHFA 3BUOB 1X6CA 1O43A 1HCSB 2LCTA 1CWDL 4U1PA 1O4GA 2HMHA 1LUMA 2H5KA 2HUWA 2ETZA 5D0JA 5J3XA 1LUIA 2RSYA 1O4RA 1Y1UA 4E68A 4OHEA 2SHPA 5EG3B 2KK6A 3CBLA 3BUNB 3HIZB 1F2FA 1O4KA 2DVJA 2YU7A 2AOAA 3S8NA 2DM0A 2L4KA 1Z3KA 4DGXA 2DLZA 1PICA 4TZIA 2MK2A 3VS2A 1MILA 1UURA 1YVHA 2FO0A 1A81A 3PSJA 2RMXA 2PNAA 2EKXA 4XZ0A 1O48A 3C7IA 1FBZA 1D4WA 1X0NA 3BUXB 1AD5A 2BBUA 1D4TA 1YVLA 1TZEE 4OHIA 3MXYA 4NWGA 2JYQA 4ROJA 1R1QA 4GWFA 3TKZA 2EYZA 1AYAA 4JGHA 2EO6A 2K79B 1O4NA 1K9AA 3IN7A 4F59A 1O4OA 3VS0A 2CBLA 1RQQC 1NZLA 1O41A 3OV1A 5EHPA 3VRRA 3VRPA 4GL9E 5HKWA 4NWFA 4OHLA 3BKBA 1RPYA 2C9WA 1O4HA 3N84A 2AOBA 1O4AA 5GJIA 2C0OA 2OQ1A 2LNXA 3HCKA 3GXWA 5AXIA 4QSYA 1O4CA 4JE4A 5IBSA 4FL3A 5HKZA 1BHHB 4U17A 1AYBA 1O4MA 1FU6A 1BFJA 1JYUA 2DLYA 1GRIA 2IUIA 3US4A 1A07A 1CWEA 1O4DA 1A1BA 1CSZA 3VS6A 3QWYA 1LKKA 3VROA 1UUSA 3S9KA 5HKYA 2XP1A 2CS0A 3PFVA 4FL2A 1KSWA 1M27A 4DGPA 2RVFA 5I6VA 1O4FA 3MXCA 1FMKA 1FYRA 2CI8A 2LNWA 2HCKA 1SHAA 4OHHA 5IBMA 1AB2A 1GHUA 5DF6A 4M4ZA 3PJPA 1O45A 2H8HA 1ZFPE 1KA6A 2EL8A 2FCIA 3OB2B 3UYOA 3BUMB 3OP0A 1BKLA 1KC2A 2QMSA 1Y57A 3VRZA 1AOTF 1SPSA 1MW4A 2H46E 1QCFA 2CR4A 1OPKA 4K45A 1WQUA 2PLEA 2CRHA 1R1SA 1A08A 1RJAA 2C0TA 1A1AA 2PTKA 2IZVA 4JEGA 3S8OA 2CIAA 3GQIB 4L1BB 5GJHA 1XA6A 1P13A 1QADA 1LUKA 3VGOA 1O4PA 1BG1A 1FU5A 3VS1A 1A1CA 3VRQA 4A4CA 4K11A 2HDVA 1X27A 4H34A 1HCTB 3PSKA 4H1OA 1BF5A 3PS5A 2L6KA 2Y3AB 3NHNA 1JYRA 1OPLA 3PQZA 1R1PA 4X6SA 1AYDA 4WWQA 4F5BA 1BHHA 1OO3A 1AYCA 3KFJA 1CJ1A 1IS0A 5KAZA 3ZNIA 3N8MA 1A1EA 2GE9A 1F1WA 5DC4A 3CD3A 1SHDA 3TL0A 3VS4A 1O46A 3VRYA 3IMJA 3CXLA 1BM2A 3BUWB 2AUGA 1LCKA 1KA7A 4XZ1A 4P9ZA 2EYVA 2RORA 5BO4A 1LKLA 5AULA 2DX0A 1O42A 1JYQA 1BLKA 2YSXA 4LUEA 1G83A 5DC9A
chains in the Genus database with same CATH superfamily
3T04A 4K44A 5EELA 4EIHA 2EOBA 4EY0A 3IMDA 2EO3A 2PNBA 2L3TA 1JWOA 1AOUF 1OO4A 3CWGA 2HDXA 2EU0A 3VS5A 1A09A 2EYYA 4P9VA 1LCJA 3HHMB 3LYVA 3VRNA 1M61A 2PLDA 1NRVA 4D8KA 4FBNA 3EAZA 2IUGA 4F5AA 2VIFA 1BKMA 1O4EA 5EHRA 3VS3A 2ABLA 2OZOA 1BLJA 2Y1NA 2K7AB 2IUHA 2LQNA 3OVEA 5DC0B 3K2TA 3N7YA 1BMBA 2DCRA 1O4IA 4LUDA 4GPLB 1B47A 1D1ZA 2LQWA 2B3OA 1O49A 2KGYA 3M7FA 2MRKA 2C0IA 1IJRA 1O4LA 3IN8A 1LUNA 3QWXX 2SRCA 1TCEA 1H9OA 3GXXA 4OHDA 1O44A 3PLFB 4K2RA 2MQIA 2GSBA 2CI9A 1O4BA 3EACA 1NZVA 1QG1E 1JU5A 4E93A 2MRJA 1I3ZA 3UF4A 5CDWA 3S8LA 1CSYA 3VS7A 2Y1MA 1O4JA 1O47A 1SPRA 4A4BA 1BFIA 1O4QA 3WA4A 2ECDA 1SHBA 1FBVA 1SKJA 1FHSA 2KNOA 5EEQA 3K2MA 3MAZA 3OB1B 2MC1A 1BHFA 3BUOB 1X6CA 1O43A 1HCSB 2LCTA 1CWDL 4U1PA 1O4GA 2HMHA 1LUMA 2H5KA 2HUWA 2ETZA 5D0JA 5J3XA 1LUIA 2RSYA 1O4RA 1Y1UA 4E68A 4OHEA 2SHPA 5EG3B 2KK6A 3CBLA 3BUNB 3HIZB 1F2FA 1O4KA 2DVJA 2YU7A 2AOAA 3S8NA 2DM0A 2L4KA 1Z3KA 4DGXA 2DLZA 1PICA 4TZIA 2MK2A 3VS2A 1MILA 1UURA 1YVHA 2FO0A 1A81A 3PSJA 2RMXA 2PNAA 2EKXA 4XZ0A 1O48A 3C7IA 1FBZA 1D4WA 1X0NA 3BUXB 1AD5A 2BBUA 1D4TA 1YVLA 1TZEE 4OHIA 3MXYA 4NWGA 2JYQA 4ROJA 1R1QA 4GWFA 3TKZA 2EYZA 1AYAA 4JGHA 2EO6A 2K79B 1O4NA 1K9AA 3IN7A 4F59A 1O4OA 3VS0A 2CBLA 1RQQC 1NZLA 1O41A 3OV1A 5EHPA 3VRRA 3VRPA 4GL9E 5HKWA 4NWFA 4OHLA 3BKBA 1RPYA 2C9WA 1O4HA 3N84A 2AOBA 1O4AA 5GJIA 2C0OA 2OQ1A 2LNXA 3HCKA 3GXWA 5AXIA 4QSYA 1O4CA 4JE4A 5IBSA 4FL3A 5HKZA 1BHHB 4U17A 1AYBA 1O4MA 1FU6A 1BFJA 1JYUA 2DLYA 1GRIA 2IUIA 3US4A 1A07A 1CWEA 1O4DA 1A1BA 1CSZA 3VS6A 3QWYA 1LKKA 3VROA 1UUSA 3S9KA 5HKYA 2XP1A 2CS0A 3PFVA 4FL2A 1KSWA 1M27A 4DGPA 2RVFA 5I6VA 1O4FA 3MXCA 1FMKA 1FYRA 2CI8A 2LNWA 2HCKA 1SHAA 4OHHA 5IBMA 1AB2A 1GHUA 5DF6A 4M4ZA 3PJPA 1O45A 2H8HA 1ZFPE 1KA6A 2EL8A 2FCIA 3OB2B 3UYOA 3BUMB 3OP0A 1BKLA 1KC2A 2QMSA 1Y57A 3VRZA 1AOTF 1SPSA 1MW4A 2H46E 1QCFA 2CR4A 1OPKA 4K45A 1WQUA 2PLEA 2CRHA 1R1SA 1A08A 1RJAA 2C0TA 1A1AA 2PTKA 2IZVA 4JEGA 3S8OA 2CIAA 3GQIB 4L1BB 5GJHA 1XA6A 1P13A 1QADA 1LUKA 3VGOA 1O4PA 2LRAA 1BG1A 1FU5A 3VS1A 1A1CA 3VRQA 4A4CA 4K11A 2HDVA 1X27A 4H34A 1HCTB 3PSKA 4H1OA 1BF5A 3PS5A 2L6KA 2Y3AB 3NHNA 1JYRA 1OPLA 3PQZA 1R1PA 4X6SA 1AYDA 4WWQA 4F5BA 1BHHA 1OO3A 1AYCA 3KFJA 1CJ1A 1IS0A 5KAZA 3ZNIA 3N8MA 1A1EA 2GE9A 1F1WA 5DC4A 3CD3A 1SHDA 3TL0A 3VS4A 1O46A 3VRYA 3IMJA 3CXLA 1BM2A 3BUWB 2AUGA 1LCKA 1KA7A 4XZ1A 4P9ZA 2EYVA 2RORA 5BO4A 1LKLA 5AULA 2DX0A 1O42A 1JYQA 1BLKA 2YSXA 4LUEA 1G83A 5DC9A
chains in the Genus database with same CATH topology
3T04A 4K44A 5EELA 4EIHA 2EOBA 4EY0A 3IMDA 2EO3A 2PNBA 2L3TA 1JWOA 1AOUF 1OO4A 3CWGA 2HDXA 2EU0A 3VS5A 1A09A 2EYYA 4P9VA 1LCJA 3HHMB 3VRNA 1M61A 2PLDA 1NRVA 4D8KA 4FBNA 3EAZA 2IUGA 4F5AA 2VIFA 1BKMA 1O4EA 5EHRA 3VS3A 2ABLA 2OZOA 1BLJA 2Y1NA 2K7AB 2IUHA 2LQNA 3OVEA 5DC0B 3N7YA 1BMBA 2DCRA 1O4IA 4LUDA 4GPLB 1B47A 1D1ZA 2LQWA 2B3OA 1O49A 3M7FA 2MRKA 2C0IA 1IJRA 1O4LA 3IN8A 1LUNA 3QWXX 2SRCA 1TCEA 1H9OA 3GXXA 4OHDA 1O44A 3PLFB 4K2RA 2MQIA 2GSBA 2CI9A 1O4BA 3EACA 1NZVA 1QG1E 1JU5A 4E93A 2MRJA 1I3ZA 3UF4A 5CDWA 3S8LA 1CSYA 3VS7A 2Y1MA 1O4JA 1O47A 1SPRA 4A4BA 1BFIA 1O4QA 3WA4A 2ECDA 1SHBA 1FBVA 1SKJA 1FHSA 2KNOA 5EEQA 3K2MA 3MAZA 3OB1B 2MC1A 1BHFA 3BUOB 1X6CA 1O43A 1HCSB 2LCTA 1CWDL 4U1PA 1O4GA 2HMHA 1LUMA 2H5KA 2HUWA 2ETZA 5D0JA 5J3XA 1LUIA 2RSYA 1O4RA 1Y1UA 4E68A 4OHEA 2SHPA 5EG3B 2KK6A 3CBLA 3BUNB 3HIZB 1F2FA 1O4KA 2DVJA 2YU7A 2AOAA 3S8NA 2DM0A 2L4KA 1Z3KA 4DGXA 2DLZA 1PICA 4TZIA 2MK2A 3VS2A 1MILA 1UURA 1YVHA 2FO0A 1A81A 3PSJA 2RMXA 2PNAA 2EKXA 4XZ0A 1O48A 3C7IA 1FBZA 1D4WA 1X0NA 3BUXB 1AD5A 2BBUA 1D4TA 1YVLA 1TZEE 4OHIA 3MXYA 4NWGA 2JYQA 4ROJA 1R1QA 4GWFA 3TKZA 2EYZA 1AYAA 4JGHA 2EO6A 2K79B 1O4NA 1K9AA 3IN7A 4F59A 1O4OA 3VS0A 2CBLA 1RQQC 1NZLA 1O41A 3OV1A 5EHPA 3VRRA 3VRPA 4GL9E 5HKWA 4NWFA 4OHLA 3BKBA 1RPYA 2C9WA 1O4HA 3N84A 2AOBA 1O4AA 5GJIA 2C0OA 2OQ1A 2LNXA 3HCKA 3GXWA 5AXIA 4QSYA 1O4CA 4JE4A 5IBSA 4FL3A 5HKZA 1BHHB 4U17A 1AYBA 1O4MA 1FU6A 1BFJA 1JYUA 2DLYA 1GRIA 2IUIA 3US4A 1A07A 1CWEA 1O4DA 1A1BA 1CSZA 3VS6A 3QWYA 1LKKA 3VROA 1UUSA 3S9KA 5HKYA 2XP1A 2CS0A 3PFVA 4FL2A 1KSWA 1M27A 4DGPA 2RVFA 5I6VA 1O4FA 3MXCA 1FMKA 1FYRA 2CI8A 2LNWA 2HCKA 1SHAA 4OHHA 5IBMA 1AB2A 1GHUA 5DF6A 4M4ZA 3PJPA 1O45A 2H8HA 1ZFPE 1KA6A 2EL8A 2FCIA 3OB2B 3UYOA 3BUMB 3OP0A 1BKLA 1KC2A 2QMSA 1Y57A 3VRZA 1AOTF 1SPSA 1MW4A 2H46E 1QCFA 2CR4A 1OPKA 4K45A 1WQUA 2PLEA 2CRHA 1R1SA 1A08A 1RJAA 2C0TA 1A1AA 2PTKA 2IZVA 4JEGA 3S8OA 2CIAA 3GQIB 4L1BB 5GJHA 1XA6A 1P13A 1QADA 1LUKA 3VGOA 1O4PA 1BG1A 1FU5A 3VS1A 1A1CA 3VRQA 4A4CA 4K11A 2HDVA 1X27A 4H34A 1HCTB 3PSKA 4H1OA 1BF5A 3PS5A 2L6KA 2Y3AB 3NHNA 1JYRA 1OPLA 3PQZA 1R1PA 4X6SA 1AYDA 4WWQA 4F5BA 1BHHA 1OO3A 1AYCA 3KFJA 1CJ1A 1IS0A 5KAZA 3ZNIA 3N8MA 1A1EA 2GE9A 1F1WA 5DC4A 3CD3A 1SHDA 3TL0A 3VS4A 1O46A 3VRYA 3IMJA 3CXLA 1BM2A 3BUWB 2AUGA 1LCKA 1KA7A 4XZ1A 4P9ZA 2EYVA 2RORA 5BO4A 1LKLA 5AULA 2DX0A 1O42A 1JYQA 1BLKA 2YSXA 4LUEA 1G83A 5DC9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T04 A;  4K44 A;  5EEL A;  4EIH A;  2EOB A;  4EY0 A;  3IMD A;  2EO3 A;  2PNB A;  2L3T A;  1JWO A;  1AOU F;  1OO4 A;  3CWG A;  2HDX A;  2EU0 A;  3VS5 A;  1A09 A;  2EYY A;  4P9V A;  1LCJ A;  3HHM B;  3VRN A;  1M61 A;  2PLD A;  1NRV A;  4D8K A;  4FBN A;  3EAZ A;  2IUG A;  4F5A A;  2VIF A;  1BKM A;  1O4E A;  5EHR A;  3VS3 A;  2ABL A;  2OZO A;  1BLJ A;  2Y1N A;  2K7A B;  2IUH A;  2LQN A;  3OVE A;  5DC0 B;  3N7Y A;  1BMB A;  2DCR A;  1O4I A;  4LUD A;  4GPL B;  1B47 A;  1D1Z A;  2LQW A;  2B3O A;  1O49 A;  3M7F A;  2MRK A;  2C0I A;  1IJR A;  1O4L A;  3IN8 A;  1LUN A;  3QWX X;  2SRC A;  1TCE A;  1H9O A;  3GXX A;  4OHD A;  1O44 A;  3PLF B;  4K2R A;  2MQI A;  2GSB A;  2CI9 A;  1O4B A;  3EAC A;  1NZV A;  1QG1 E;  1JU5 A;  4E93 A;  2MRJ A;  1I3Z A;  3UF4 A;  5CDW A;  3S8L A;  1CSY A;  3VS7 A;  2Y1M A;  1O4J A;  1O47 A;  1SPR A;  4A4B A;  1BFI A;  1O4Q A;  3WA4 A;  2ECD A;  1SHB A;  1FBV A;  1SKJ A;  1FHS A;  2KNO A;  5EEQ A;  3K2M A;  3MAZ A;  3OB1 B;  2MC1 A;  1BHF A;  3BUO B;  1X6C A;  1O43 A;  1HCS B;  2LCT A;  1CWD L;  4U1P A;  1O4G A;  2HMH A;  1LUM A;  2H5K A;  2HUW A;  2ETZ A;  5D0J A;  5J3X A;  1LUI A;  2RSY A;  1O4R A;  1Y1U A;  4E68 A;  4OHE A;  2SHP A;  5EG3 B;  2KK6 A;  3CBL A;  3BUN B;  3HIZ B;  1F2F A;  1O4K A;  2DVJ A;  2YU7 A;  2AOA A;  3S8N A;  2DM0 A;  2L4K A;  1Z3K A;  4DGX A;  2DLZ A;  1PIC A;  4TZI A;  2MK2 A;  3VS2 A;  1MIL A;  1UUR A;  1YVH A;  2FO0 A;  1A81 A;  3PSJ A;  2RMX A;  2PNA A;  2EKX A;  4XZ0 A;  1O48 A;  3C7I A;  1FBZ A;  1D4W A;  1X0N A;  3BUX B;  1AD5 A;  2BBU A;  1D4T A;  1YVL A;  1TZE E;  4OHI A;  3MXY A;  4NWG A;  2JYQ A;  4ROJ A;  1R1Q A;  4GWF A;  3TKZ A;  2EYZ A;  1AYA A;  4JGH A;  2EO6 A;  2K79 B;  1O4N A;  1K9A A;  3IN7 A;  4F59 A;  1O4O A;  3VS0 A;  2CBL A;  1RQQ C;  1NZL A;  1O41 A;  3OV1 A;  5EHP A;  3VRR A;  3VRP A;  4GL9 E;  5HKW A;  4NWF A;  4OHL A;  3BKB A;  1RPY A;  2C9W A;  1O4H A;  3N84 A;  2AOB A;  1O4A A;  5GJI A;  2C0O A;  2OQ1 A;  2LNX A;  3HCK A;  3GXW A;  5AXI A;  4QSY A;  1O4C A;  4JE4 A;  5IBS A;  4FL3 A;  5HKZ A;  1BHH B;  4U17 A;  1AYB A;  1O4M A;  1FU6 A;  1BFJ A;  1JYU A;  2DLY A;  1GRI A;  2IUI A;  3US4 A;  1A07 A;  1CWE A;  1O4D A;  1A1B A;  1CSZ A;  3VS6 A;  3QWY A;  1LKK A;  3VRO A;  1UUS A;  3S9K A;  5HKY A;  2XP1 A;  2CS0 A;  3PFV A;  4FL2 A;  1KSW A;  1M27 A;  4DGP A;  2RVF A;  5I6V A;  1O4F A;  3MXC A;  1FMK A;  1FYR A;  2CI8 A;  2LNW A;  2HCK A;  1SHA A;  4OHH A;  5IBM A;  1AB2 A;  1GHU A;  5DF6 A;  4M4Z A;  3PJP A;  1O45 A;  2H8H A;  1ZFP E;  1KA6 A;  2EL8 A;  2FCI A;  3OB2 B;  3UYO A;  3BUM B;  3OP0 A;  1BKL A;  1KC2 A;  2QMS A;  1Y57 A;  3VRZ A;  1AOT F;  1SPS A;  1MW4 A;  2H46 E;  1QCF A;  2CR4 A;  1OPK A;  4K45 A;  1WQU A;  2PLE A;  2CRH A;  1R1S A;  1A08 A;  1RJA A;  2C0T A;  1A1A A;  2PTK A;  2IZV A;  4JEG A;  3S8O A;  2CIA A;  3GQI B;  4L1B B;  5GJH A;  1XA6 A;  1P13 A;  1QAD A;  1LUK A;  3VGO A;  1O4P A;  1BG1 A;  1FU5 A;  3VS1 A;  1A1C A;  3VRQ A;  4A4C A;  4K11 A;  2HDV A;  1X27 A;  4H34 A;  1HCT B;  3PSK A;  4H1O A;  1BF5 A;  3PS5 A;  2L6K A;  2Y3A B;  3NHN A;  1JYR A;  1OPL A;  3PQZ A;  1R1P A;  4X6S A;  1AYD A;  4WWQ A;  4F5B A;  1BHH A;  1OO3 A;  1AYC A;  3KFJ A;  1CJ1 A;  1IS0 A;  5KAZ A;  3ZNI A;  3N8M A;  1A1E A;  2GE9 A;  1F1W A;  5DC4 A;  3CD3 A;  1SHD A;  3TL0 A;  3VS4 A;  1O46 A;  3VRY A;  3IMJ A;  3CXL A;  1BM2 A;  3BUW B;  2AUG A;  1LCK A;  1KA7 A;  4XZ1 A;  4P9Z A;  2EYV A;  2ROR A;  5BO4 A;  1LKL A;  5AUL A;  2DX0 A;  1O42 A;  1JYQ A;  1BLK A;  2YSX A;  4LUE A;  1G83 A;  5DC9 A; 
#chains in the Genus database with same CATH topology
 3T04 A;  4K44 A;  5EEL A;  4EIH A;  2EOB A;  4EY0 A;  3IMD A;  2EO3 A;  2PNB A;  2L3T A;  1JWO A;  1AOU F;  1OO4 A;  3CWG A;  2HDX A;  2EU0 A;  3VS5 A;  1A09 A;  2EYY A;  4P9V A;  1LCJ A;  3HHM B;  3LYV A;  3VRN A;  1M61 A;  2PLD A;  1NRV A;  4D8K A;  4FBN A;  3EAZ A;  2IUG A;  4F5A A;  2VIF A;  1BKM A;  1O4E A;  5EHR A;  3VS3 A;  2ABL A;  2OZO A;  1BLJ A;  2Y1N A;  2K7A B;  2IUH A;  2LQN A;  3OVE A;  5DC0 B;  3K2T A;  3N7Y A;  1BMB A;  2DCR A;  1O4I A;  4LUD A;  4GPL B;  1B47 A;  1D1Z A;  2LQW A;  2B3O A;  1O49 A;  2KGY A;  3M7F A;  2MRK A;  2C0I A;  1IJR A;  1O4L A;  3IN8 A;  1LUN A;  3QWX X;  2SRC A;  1TCE A;  1H9O A;  3GXX A;  4OHD A;  1O44 A;  3PLF B;  4K2R A;  2MQI A;  2GSB A;  2CI9 A;  1O4B A;  3EAC A;  1NZV A;  1QG1 E;  1JU5 A;  4E93 A;  2MRJ A;  1I3Z A;  3UF4 A;  5CDW A;  3S8L A;  1CSY A;  3VS7 A;  2Y1M A;  1O4J A;  1O47 A;  1SPR A;  4A4B A;  1BFI A;  1O4Q A;  3WA4 A;  2ECD A;  1SHB A;  1FBV A;  1SKJ A;  1FHS A;  2KNO A;  5EEQ A;  3K2M A;  3MAZ A;  3OB1 B;  2MC1 A;  1BHF A;  3BUO B;  1X6C A;  1O43 A;  1HCS B;  2LCT A;  1CWD L;  4U1P A;  1O4G A;  2HMH A;  1LUM A;  2H5K A;  2HUW A;  2ETZ A;  5D0J A;  5J3X A;  1LUI A;  2RSY A;  1O4R A;  1Y1U A;  4E68 A;  4OHE A;  2SHP A;  5EG3 B;  2KK6 A;  3CBL A;  3BUN B;  3HIZ B;  1F2F A;  1O4K A;  2DVJ A;  2YU7 A;  2AOA A;  3S8N A;  2DM0 A;  2L4K A;  1Z3K A;  4DGX A;  2DLZ A;  1PIC A;  4TZI A;  2MK2 A;  3VS2 A;  1MIL A;  1UUR A;  1YVH A;  2FO0 A;  1A81 A;  3PSJ A;  2RMX A;  2PNA A;  2EKX A;  4XZ0 A;  1O48 A;  3C7I A;  1FBZ A;  1D4W A;  1X0N A;  3BUX B;  1AD5 A;  2BBU A;  1D4T A;  1YVL A;  1TZE E;  4OHI A;  3MXY A;  4NWG A;  2JYQ A;  4ROJ A;  1R1Q A;  4GWF A;  3TKZ A;  2EYZ A;  1AYA A;  4JGH A;  2EO6 A;  2K79 B;  1O4N A;  1K9A A;  3IN7 A;  4F59 A;  1O4O A;  3VS0 A;  2CBL A;  1RQQ C;  1NZL A;  1O41 A;  3OV1 A;  5EHP A;  3VRR A;  3VRP A;  4GL9 E;  5HKW A;  4NWF A;  4OHL A;  3BKB A;  1RPY A;  2C9W A;  1O4H A;  3N84 A;  2AOB A;  1O4A A;  5GJI A;  2C0O A;  2OQ1 A;  2LNX A;  3HCK A;  3GXW A;  5AXI A;  4QSY A;  1O4C A;  4JE4 A;  5IBS A;  4FL3 A;  5HKZ A;  1BHH B;  4U17 A;  1AYB A;  1O4M A;  1FU6 A;  1BFJ A;  1JYU A;  2DLY A;  1GRI A;  2IUI A;  3US4 A;  1A07 A;  1CWE A;  1O4D A;  1A1B A;  1CSZ A;  3VS6 A;  3QWY A;  1LKK A;  3VRO A;  1UUS A;  3S9K A;  5HKY A;  2XP1 A;  2CS0 A;  3PFV A;  4FL2 A;  1KSW A;  1M27 A;  4DGP A;  2RVF A;  5I6V A;  1O4F A;  3MXC A;  1FMK A;  1FYR A;  2CI8 A;  2LNW A;  2HCK A;  1SHA A;  4OHH A;  5IBM A;  1AB2 A;  1GHU A;  5DF6 A;  4M4Z A;  3PJP A;  1O45 A;  2H8H A;  1ZFP E;  1KA6 A;  2EL8 A;  2FCI A;  3OB2 B;  3UYO A;  3BUM B;  3OP0 A;  1BKL A;  1KC2 A;  2QMS A;  1Y57 A;  3VRZ A;  1AOT F;  1SPS A;  1MW4 A;  2H46 E;  1QCF A;  2CR4 A;  1OPK A;  4K45 A;  1WQU A;  2PLE A;  2CRH A;  1R1S A;  1A08 A;  1RJA A;  2C0T A;  1A1A A;  2PTK A;  2IZV A;  4JEG A;  3S8O A;  2CIA A;  3GQI B;  4L1B B;  5GJH A;  1XA6 A;  1P13 A;  1QAD A;  1LUK A;  3VGO A;  1O4P A;  2LRA A;  1BG1 A;  1FU5 A;  3VS1 A;  1A1C A;  3VRQ A;  4A4C A;  4K11 A;  2HDV A;  1X27 A;  4H34 A;  1HCT B;  3PSK A;  4H1O A;  1BF5 A;  3PS5 A;  2L6K A;  2Y3A B;  3NHN A;  1JYR A;  1OPL A;  3PQZ A;  1R1P A;  4X6S A;  1AYD A;  4WWQ A;  4F5B A;  1BHH A;  1OO3 A;  1AYC A;  3KFJ A;  1CJ1 A;  1IS0 A;  5KAZ A;  3ZNI A;  3N8M A;  1A1E A;  2GE9 A;  1F1W A;  5DC4 A;  3CD3 A;  1SHD A;  3TL0 A;  3VS4 A;  1O46 A;  3VRY A;  3IMJ A;  3CXL A;  1BM2 A;  3BUW B;  2AUG A;  1LCK A;  1KA7 A;  4XZ1 A;  4P9Z A;  2EYV A;  2ROR A;  5BO4 A;  1LKL A;  5AUL A;  2DX0 A;  1O42 A;  1JYQ A;  1BLK A;  2YSX A;  4LUE A;  1G83 A;  5DC9 A; 
#chains in the Genus database with same CATH homology
 3T04 A;  4K44 A;  5EEL A;  4EIH A;  2EOB A;  4EY0 A;  3IMD A;  2EO3 A;  2PNB A;  2L3T A;  1JWO A;  1AOU F;  1OO4 A;  3CWG A;  2HDX A;  2EU0 A;  3VS5 A;  1A09 A;  2EYY A;  4P9V A;  1LCJ A;  3HHM B;  3VRN A;  1M61 A;  2PLD A;  1NRV A;  4D8K A;  4FBN A;  3EAZ A;  2IUG A;  4F5A A;  2VIF A;  1BKM A;  1O4E A;  5EHR A;  3VS3 A;  2ABL A;  2OZO A;  1BLJ A;  2Y1N A;  2K7A B;  2IUH A;  2LQN A;  3OVE A;  5DC0 B;  3N7Y A;  1BMB A;  2DCR A;  1O4I A;  4LUD A;  4GPL B;  1B47 A;  1D1Z A;  2LQW A;  2B3O A;  1O49 A;  3M7F A;  2MRK A;  2C0I A;  1IJR A;  1O4L A;  3IN8 A;  1LUN A;  3QWX X;  2SRC A;  1TCE A;  1H9O A;  3GXX A;  4OHD A;  1O44 A;  3PLF B;  4K2R A;  2MQI A;  2GSB A;  2CI9 A;  1O4B A;  3EAC A;  1NZV A;  1QG1 E;  1JU5 A;  4E93 A;  2MRJ A;  1I3Z A;  3UF4 A;  5CDW A;  3S8L A;  1CSY A;  3VS7 A;  2Y1M A;  1O4J A;  1O47 A;  1SPR A;  4A4B A;  1BFI A;  1O4Q A;  3WA4 A;  2ECD A;  1SHB A;  1FBV A;  1SKJ A;  1FHS A;  2KNO A;  5EEQ A;  3K2M A;  3MAZ A;  3OB1 B;  2MC1 A;  1BHF A;  3BUO B;  1X6C A;  1O43 A;  1HCS B;  2LCT A;  1CWD L;  4U1P A;  1O4G A;  2HMH A;  1LUM A;  2H5K A;  2HUW A;  2ETZ A;  5D0J A;  5J3X A;  1LUI A;  2RSY A;  1O4R A;  1Y1U A;  4E68 A;  4OHE A;  2SHP A;  5EG3 B;  2KK6 A;  3CBL A;  3BUN B;  3HIZ B;  1F2F A;  1O4K A;  2DVJ A;  2YU7 A;  2AOA A;  3S8N A;  2DM0 A;  2L4K A;  1Z3K A;  4DGX A;  2DLZ A;  1PIC A;  4TZI A;  2MK2 A;  3VS2 A;  1MIL A;  1UUR A;  1YVH A;  2FO0 A;  1A81 A;  3PSJ A;  2RMX A;  2PNA A;  2EKX A;  4XZ0 A;  1O48 A;  3C7I A;  1FBZ A;  1D4W A;  1X0N A;  3BUX B;  1AD5 A;  2BBU A;  1D4T A;  1YVL A;  1TZE E;  4OHI A;  3MXY A;  4NWG A;  2JYQ A;  4ROJ A;  1R1Q A;  4GWF A;  3TKZ A;  2EYZ A;  1AYA A;  4JGH A;  2EO6 A;  2K79 B;  1O4N A;  1K9A A;  3IN7 A;  4F59 A;  1O4O A;  3VS0 A;  2CBL A;  1RQQ C;  1NZL A;  1O41 A;  3OV1 A;  5EHP A;  3VRR A;  3VRP A;  4GL9 E;  5HKW A;  4NWF A;  4OHL A;  3BKB A;  1RPY A;  2C9W A;  1O4H A;  3N84 A;  2AOB A;  1O4A A;  5GJI A;  2C0O A;  2OQ1 A;  2LNX A;  3HCK A;  3GXW A;  5AXI A;  4QSY A;  1O4C A;  4JE4 A;  5IBS A;  4FL3 A;  5HKZ A;  1BHH B;  4U17 A;  1AYB A;  1O4M A;  1FU6 A;  1BFJ A;  1JYU A;  2DLY A;  1GRI A;  2IUI A;  3US4 A;  1A07 A;  1CWE A;  1O4D A;  1A1B A;  1CSZ A;  3VS6 A;  3QWY A;  1LKK A;  3VRO A;  1UUS A;  3S9K A;  5HKY A;  2XP1 A;  2CS0 A;  3PFV A;  4FL2 A;  1KSW A;  1M27 A;  4DGP A;  2RVF A;  5I6V A;  1O4F A;  3MXC A;  1FMK A;  1FYR A;  2CI8 A;  2LNW A;  2HCK A;  1SHA A;  4OHH A;  5IBM A;  1AB2 A;  1GHU A;  5DF6 A;  4M4Z A;  3PJP A;  1O45 A;  2H8H A;  1ZFP E;  1KA6 A;  2EL8 A;  2FCI A;  3OB2 B;  3UYO A;  3BUM B;  3OP0 A;  1BKL A;  1KC2 A;  2QMS A;  1Y57 A;  3VRZ A;  1AOT F;  1SPS A;  1MW4 A;  2H46 E;  1QCF A;  2CR4 A;  1OPK A;  4K45 A;  1WQU A;  2PLE A;  2CRH A;  1R1S A;  1A08 A;  1RJA A;  2C0T A;  1A1A A;  2PTK A;  2IZV A;  4JEG A;  3S8O A;  2CIA A;  3GQI B;  4L1B B;  5GJH A;  1XA6 A;  1P13 A;  1QAD A;  1LUK A;  3VGO A;  1O4P A;  1BG1 A;  1FU5 A;  3VS1 A;  1A1C A;  3VRQ A;  4A4C A;  4K11 A;  2HDV A;  1X27 A;  4H34 A;  1HCT B;  3PSK A;  4H1O A;  1BF5 A;  3PS5 A;  2L6K A;  2Y3A B;  3NHN A;  1JYR A;  1OPL A;  3PQZ A;  1R1P A;  4X6S A;  1AYD A;  4WWQ A;  4F5B A;  1BHH A;  1OO3 A;  1AYC A;  3KFJ A;  1CJ1 A;  1IS0 A;  5KAZ A;  3ZNI A;  3N8M A;  1A1E A;  2GE9 A;  1F1W A;  5DC4 A;  3CD3 A;  1SHD A;  3TL0 A;  3VS4 A;  1O46 A;  3VRY A;  3IMJ A;  3CXL A;  1BM2 A;  3BUW B;  2AUG A;  1LCK A;  1KA7 A;  4XZ1 A;  4P9Z A;  2EYV A;  2ROR A;  5BO4 A;  1LKL A;  5AUL A;  2DX0 A;  1O42 A;  1JYQ A;  1BLK A;  2YSX A;  4LUE A;  1G83 A;  5DC9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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