1O4GA

Crystal structure of sh2 in complex with dpi59.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4gA00
1TZEE 1QCFA 2DM0A 3BUXB 1O4FA 1A09A 3IN8A 5GJIA 2MK2A 3QWXX 2CI9A 1M27A 1K9AA 1R1PA 1A08A 1Y57A 2KNOA 3VS3A 3IMDA 2AOAA 1O45A 3MAZA 1CJ1A 3QWYA 4U17A 1O49A 5AULA 5DF6A 4OHDA 1BKMA 1BKLA 2HDVA 3CBLA 1F1WA 4F59A 1AB2A 1O4PA 2DCRA 2LNXA 1OPLA 1TCEA 5D0JA 1I3ZA 3PLFB 2RORA 1SPRA 5IBMA 3VS7A 5DC4A 1B47A 3OP0A 2ECDA 1BM2A 3OB1B 1GRIA 5IBSA 1JWOA 1O42A 2K79B 3C7IA 3M7FA 4D8KA 2GSBA 4ROJA 1R1SA 3VS2A 1KC2A 1A1BA 2K7AB 2KK6A 4LUDA 3GQIB 1BHFA 3S8LA 2GE9A 3BUOB 1F2FA 1M61A 3EAZA 3PSKA 3VRZA 3MXCA 2ABLA 5HKYA 2EU0A 3VGOA 1O46A 1O4IA 3K2MA 1GHUA 1QADA 1LKKA 2PTKA 1O4QA 4X6SA 1LCKA 2DLYA 2EO6A 4TZIA 5BO4A 2VIFA 4XZ1A 3ZNIA 1D4TA 2LQWA 2EOBA 1D4WA 3S9KA 1RPYA 3HIZB 1H9OA 2PNBA 1KSWA 2IZVA 1CSYA 4XZ0A 1QG1E 1BF5A 5DC9A 3PJPA 2IUHA 3OV1A 2HDXA 1OPKA 4P9ZA 2PLEA 4L1BB 2BBUA 4OHEA 5EEQA 2IUIA 1D1ZA 1IJRA 3WA4A 1SPSA 1O4EA 2EYVA 4DGPA 2H5KA 3NHNA 2PNAA 2CS0A 4K45A 1BFIA 1Y1UA 2RVFA 1A1EA 1O48A 1FU5A 2MRJA 2QMSA 1LUIA 1FYRA 1CWDL 2EO3A 2C0OA 5EHPA 1O47A 3BUMB 3VS0A 3CWGA 1O4LA 1RJAA 2HCKA 1JU5A 2RMXA 5DC0B 2HUWA 1JYUA 3BUWB 1LKLA 4JGHA 3UYOA 1BHHB 5GJHA 1LUKA 2Y3AB 1O4MA 1ZFPE 4H1OA 4M4ZA 4FBNA 3KFJA 3CXLA 2EKXA 4FL2A 4K2RA 1BFJA 2OQ1A 1O44A 1KA6A 1A1AA 4P9VA 3US4A 2C0IA 3EACA 1NZVA 3VRYA 2YSXA 1CSZA 2CIAA 1LUNA 4EY0A 4F5AA 4U1PA 2OZOA 3HCKA 1BLKA 3S8NA 1AD5A 2ETZA 2HMHA 4A4BA 1O4HA 2FO0A 3TL0A 1LUMA 1MILA 4LUEA 1FHSA 1P13A 2RSYA 4GWFA 2Y1MA 1IS0A 1O4DA 1SHBA 4EIHA 1BMBA 2CR4A 3N84A 1RQQC 3VRPA 2AOBA 3TKZA 2LQNA 1O4NA 3CD3A 1AYDA 2SRCA 1PICA 1O4CA 1KA7A 1O4RA 1X0NA 5EHRA 3VRRA 1FMKA 1R1QA 4NWFA 2EYZA 2XP1A 5EELA 3GXXA 5KAZA 4QSYA 5CDWA 1MW4A 3VS5A 4WWQA 3BUNB 3OB2B 2L6KA 3PS5A 4F5BA 2H46E 1BHHA 1JYQA 1CWEA 1O4KA 3N7YA 4OHLA 1AYAA 3BKBA 1WQUA 2IUGA 3VRNA 1G83A 3VS6A 1NRVA 1O4JA 4JEGA 2CBLA 1X27A 2DX0A 2CRHA 4E68A 2L3TA 1SKJA 4H34A 1A1CA 1AYBA 4FL3A 2YU7A 1OO4A 3S8OA 4A4CA 2B3OA 3VS1A 1O4AA 4K44A 3UF4A 3VRQA 1LCJA 4NWGA 2MC1A 1YVHA 1X6CA 1JYRA 1AOUF 1UURA 1HCSB 1OO3A 1UUSA 5J3XA 1A81A 2L4KA 1AYCA 3PQZA 5AXIA 1YVLA 1Z3KA 1NZLA 4DGXA 4JE4A 2EYYA 4K11A 4OHIA 1O41A 4OHHA 1A07A 3GXWA 3VS4A 1FBVA 1BG1A 1FU6A 3OVEA 2DVJA 3VROA 5HKWA 1O4BA 3N8MA 1BLJA 3PSJA 2AUGA 1HCTB 4GL9E 2Y1NA 2C0TA 3HHMB 5EG3B 5I6VA 2LNWA 3IMJA 1SHAA 1O43A 2LCTA 3T04A 1AOTF 1O4GA 2MQIA 2JYQA 2MRKA 1O4OA 2DLZA 2C9WA 1XA6A 2CI8A 3PFVA 2FCIA 2PLDA 3MXYA 3IN7A 4GPLB 2SHPA 5HKZA 4E93A 2H8HA 2EL8A 1FBZA 1SHDA
chains in the Genus database with same CATH superfamily
1TZEE 1QCFA 2DM0A 3BUXB 1O4FA 1A09A 3IN8A 5GJIA 2MK2A 3QWXX 2CI9A 1M27A 1K9AA 1R1PA 1A08A 1Y57A 2KNOA 3VS3A 3IMDA 2AOAA 1O45A 3MAZA 1CJ1A 3QWYA 4U17A 1O49A 5AULA 5DF6A 4OHDA 2LRAA 1BKMA 1BKLA 2HDVA 3CBLA 1F1WA 4F59A 1AB2A 1O4PA 2DCRA 2LNXA 1OPLA 1TCEA 5D0JA 1I3ZA 3PLFB 2RORA 1SPRA 3K2TA 5IBMA 3VS7A 5DC4A 1B47A 3OP0A 2ECDA 1BM2A 3OB1B 1GRIA 5IBSA 1JWOA 1O42A 2K79B 3C7IA 3M7FA 4D8KA 2GSBA 4ROJA 1R1SA 3VS2A 1KC2A 1A1BA 2K7AB 2KK6A 4LUDA 3GQIB 1BHFA 3S8LA 2GE9A 3BUOB 1F2FA 1M61A 3EAZA 3PSKA 3VRZA 3MXCA 2ABLA 5HKYA 2EU0A 3VGOA 1O46A 1O4IA 3K2MA 1GHUA 1QADA 1LKKA 2PTKA 1O4QA 4X6SA 1LCKA 2DLYA 2EO6A 3LYVA 4TZIA 5BO4A 2VIFA 4XZ1A 3ZNIA 1D4TA 2LQWA 2EOBA 1D4WA 3S9KA 1RPYA 3HIZB 1H9OA 2PNBA 1KSWA 2IZVA 1CSYA 4XZ0A 1QG1E 1BF5A 5DC9A 3PJPA 2IUHA 3OV1A 2HDXA 1OPKA 4P9ZA 2PLEA 4L1BB 2BBUA 4OHEA 5EEQA 2IUIA 1D1ZA 1IJRA 3WA4A 1SPSA 1O4EA 2EYVA 4DGPA 2H5KA 3NHNA 2PNAA 2CS0A 4K45A 1BFIA 1Y1UA 2RVFA 1A1EA 1O48A 1FU5A 2MRJA 2QMSA 1LUIA 1FYRA 1CWDL 2EO3A 2C0OA 5EHPA 1O47A 3BUMB 3VS0A 3CWGA 1O4LA 1RJAA 2HCKA 1JU5A 2RMXA 5DC0B 2HUWA 1JYUA 3BUWB 1LKLA 4JGHA 3UYOA 1BHHB 5GJHA 1LUKA 2Y3AB 1O4MA 1ZFPE 4H1OA 4M4ZA 4FBNA 3KFJA 3CXLA 2EKXA 4FL2A 4K2RA 1BFJA 2OQ1A 1O44A 1KA6A 1A1AA 4P9VA 3US4A 2C0IA 3EACA 1NZVA 3VRYA 2YSXA 1CSZA 2CIAA 1LUNA 4EY0A 4F5AA 4U1PA 2OZOA 3HCKA 1BLKA 3S8NA 1AD5A 2ETZA 2HMHA 4A4BA 1O4HA 2FO0A 3TL0A 1LUMA 1MILA 4LUEA 1FHSA 1P13A 2RSYA 4GWFA 2Y1MA 1IS0A 1O4DA 1SHBA 4EIHA 1BMBA 2CR4A 3N84A 1RQQC 3VRPA 2AOBA 3TKZA 2LQNA 1O4NA 3CD3A 1AYDA 2SRCA 1PICA 1O4CA 1KA7A 1O4RA 1X0NA 5EHRA 3VRRA 1FMKA 1R1QA 4NWFA 2EYZA 2XP1A 5EELA 3GXXA 5KAZA 4QSYA 5CDWA 1MW4A 3VS5A 4WWQA 3BUNB 3OB2B 2L6KA 3PS5A 4F5BA 2H46E 1BHHA 1JYQA 1CWEA 1O4KA 3N7YA 4OHLA 1AYAA 3BKBA 1WQUA 2IUGA 3VRNA 1G83A 3VS6A 1NRVA 1O4JA 2KGYA 2CBLA 4JEGA 1X27A 2DX0A 2CRHA 4E68A 2L3TA 1SKJA 4H34A 1A1CA 1AYBA 4FL3A 2YU7A 1OO4A 3S8OA 4A4CA 2B3OA 3VS1A 1O4AA 4K44A 3UF4A 3VRQA 1LCJA 4NWGA 2MC1A 1YVHA 1X6CA 1JYRA 1AOUF 1UURA 1HCSB 1OO3A 1UUSA 5J3XA 1A81A 2L4KA 1AYCA 3PQZA 5AXIA 1YVLA 1Z3KA 1NZLA 4DGXA 4JE4A 2EYYA 4K11A 4OHIA 1O41A 4OHHA 1A07A 3GXWA 3VS4A 1FBVA 1BG1A 1FU6A 3OVEA 2DVJA 3VROA 5HKWA 1O4BA 3N8MA 1BLJA 3PSJA 2AUGA 1HCTB 4GL9E 2Y1NA 2C0TA 3HHMB 5EG3B 5I6VA 2LNWA 3IMJA 1SHAA 1O43A 2LCTA 3T04A 1AOTF 1O4GA 2MQIA 2JYQA 2MRKA 1O4OA 2DLZA 2C9WA 1XA6A 2CI8A 3PFVA 2FCIA 2PLDA 3MXYA 3IN7A 4GPLB 2SHPA 5HKZA 4E93A 2H8HA 2EL8A 1FBZA 1SHDA
chains in the Genus database with same CATH topology
1TZEE 1QCFA 2DM0A 3BUXB 1O4FA 1A09A 3IN8A 5GJIA 2MK2A 3QWXX 2CI9A 1M27A 1K9AA 1R1PA 1A08A 1Y57A 2KNOA 3VS3A 3IMDA 2AOAA 1O45A 3MAZA 1CJ1A 3QWYA 4U17A 1O49A 5AULA 5DF6A 4OHDA 1BKMA 1BKLA 2HDVA 3CBLA 1F1WA 4F59A 1AB2A 1O4PA 2DCRA 2LNXA 1OPLA 1TCEA 5D0JA 1I3ZA 3PLFB 2RORA 1SPRA 5IBMA 3VS7A 5DC4A 1B47A 3OP0A 2ECDA 1BM2A 3OB1B 1GRIA 5IBSA 1JWOA 1O42A 2K79B 3C7IA 3M7FA 4D8KA 2GSBA 4ROJA 1R1SA 3VS2A 1KC2A 1A1BA 2K7AB 2KK6A 4LUDA 3GQIB 1BHFA 3S8LA 2GE9A 3BUOB 1F2FA 1M61A 3EAZA 3PSKA 3VRZA 3MXCA 2ABLA 5HKYA 2EU0A 3VGOA 1O46A 1O4IA 3K2MA 1GHUA 1QADA 1LKKA 2PTKA 1O4QA 4X6SA 1LCKA 2DLYA 2EO6A 4TZIA 5BO4A 2VIFA 4XZ1A 3ZNIA 1D4TA 2LQWA 2EOBA 1D4WA 3S9KA 1RPYA 3HIZB 1H9OA 2PNBA 1KSWA 2IZVA 1CSYA 4XZ0A 1QG1E 1BF5A 5DC9A 3PJPA 2IUHA 3OV1A 2HDXA 1OPKA 4P9ZA 2PLEA 4L1BB 2BBUA 4OHEA 5EEQA 2IUIA 1D1ZA 1IJRA 3WA4A 1SPSA 1O4EA 2EYVA 4DGPA 2H5KA 3NHNA 2PNAA 2CS0A 4K45A 1BFIA 1Y1UA 2RVFA 1A1EA 1O48A 1FU5A 2MRJA 2QMSA 1LUIA 1FYRA 1CWDL 2EO3A 2C0OA 5EHPA 1O47A 3BUMB 3VS0A 3CWGA 1O4LA 1RJAA 2HCKA 1JU5A 2RMXA 5DC0B 2HUWA 1JYUA 3BUWB 1LKLA 4JGHA 3UYOA 1BHHB 5GJHA 1LUKA 2Y3AB 1O4MA 1ZFPE 4H1OA 4M4ZA 4FBNA 3KFJA 3CXLA 2EKXA 4FL2A 4K2RA 1BFJA 2OQ1A 1O44A 1KA6A 1A1AA 4P9VA 3US4A 2C0IA 3EACA 1NZVA 3VRYA 2YSXA 1CSZA 2CIAA 1LUNA 4EY0A 4F5AA 4U1PA 2OZOA 3HCKA 1BLKA 3S8NA 1AD5A 2ETZA 2HMHA 4A4BA 1O4HA 2FO0A 3TL0A 1LUMA 1MILA 4LUEA 1FHSA 1P13A 2RSYA 4GWFA 2Y1MA 1IS0A 1O4DA 1SHBA 4EIHA 1BMBA 2CR4A 3N84A 1RQQC 3VRPA 2AOBA 3TKZA 2LQNA 1O4NA 3CD3A 1AYDA 2SRCA 1PICA 1O4CA 1KA7A 1O4RA 1X0NA 5EHRA 3VRRA 1FMKA 1R1QA 4NWFA 2EYZA 2XP1A 5EELA 3GXXA 5KAZA 4QSYA 5CDWA 1MW4A 3VS5A 4WWQA 3BUNB 3OB2B 2L6KA 3PS5A 4F5BA 2H46E 1BHHA 1JYQA 1CWEA 1O4KA 3N7YA 4OHLA 1AYAA 3BKBA 1WQUA 2IUGA 3VRNA 1G83A 3VS6A 1NRVA 1O4JA 4JEGA 2CBLA 1X27A 2DX0A 2CRHA 4E68A 2L3TA 1SKJA 4H34A 1A1CA 1AYBA 4FL3A 2YU7A 1OO4A 3S8OA 4A4CA 2B3OA 3VS1A 1O4AA 4K44A 3UF4A 3VRQA 1LCJA 4NWGA 2MC1A 1YVHA 1X6CA 1JYRA 1AOUF 1UURA 1HCSB 1OO3A 1UUSA 5J3XA 1A81A 2L4KA 1AYCA 3PQZA 5AXIA 1YVLA 1Z3KA 1NZLA 4DGXA 4JE4A 2EYYA 4K11A 4OHIA 1O41A 4OHHA 1A07A 3GXWA 3VS4A 1FBVA 1BG1A 1FU6A 3OVEA 2DVJA 3VROA 5HKWA 1O4BA 3N8MA 1BLJA 3PSJA 2AUGA 1HCTB 4GL9E 2Y1NA 2C0TA 3HHMB 5EG3B 5I6VA 2LNWA 3IMJA 1SHAA 1O43A 2LCTA 3T04A 1AOTF 1O4GA 2MQIA 2JYQA 2MRKA 1O4OA 2DLZA 2C9WA 1XA6A 2CI8A 3PFVA 2FCIA 2PLDA 3MXYA 3IN7A 4GPLB 2SHPA 5HKZA 4E93A 2H8HA 2EL8A 1FBZA 1SHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TZE E;  1QCF A;  2DM0 A;  3BUX B;  1O4F A;  1A09 A;  3IN8 A;  5GJI A;  2MK2 A;  3QWX X;  2CI9 A;  1M27 A;  1K9A A;  1R1P A;  1A08 A;  1Y57 A;  2KNO A;  3VS3 A;  3IMD A;  2AOA A;  1O45 A;  3MAZ A;  1CJ1 A;  3QWY A;  4U17 A;  1O49 A;  5AUL A;  5DF6 A;  4OHD A;  1BKM A;  1BKL A;  2HDV A;  3CBL A;  1F1W A;  4F59 A;  1AB2 A;  1O4P A;  2DCR A;  2LNX A;  1OPL A;  1TCE A;  5D0J A;  1I3Z A;  3PLF B;  2ROR A;  1SPR A;  5IBM A;  3VS7 A;  5DC4 A;  1B47 A;  3OP0 A;  2ECD A;  1BM2 A;  3OB1 B;  1GRI A;  5IBS A;  1JWO A;  1O42 A;  2K79 B;  3C7I A;  3M7F A;  4D8K A;  2GSB A;  4ROJ A;  1R1S A;  3VS2 A;  1KC2 A;  1A1B A;  2K7A B;  2KK6 A;  4LUD A;  3GQI B;  1BHF A;  3S8L A;  2GE9 A;  3BUO B;  1F2F A;  1M61 A;  3EAZ A;  3PSK A;  3VRZ A;  3MXC A;  2ABL A;  5HKY A;  2EU0 A;  3VGO A;  1O46 A;  1O4I A;  3K2M A;  1GHU A;  1QAD A;  1LKK A;  2PTK A;  1O4Q A;  4X6S A;  1LCK A;  2DLY A;  2EO6 A;  4TZI A;  5BO4 A;  2VIF A;  4XZ1 A;  3ZNI A;  1D4T A;  2LQW A;  2EOB A;  1D4W A;  3S9K A;  1RPY A;  3HIZ B;  1H9O A;  2PNB A;  1KSW A;  2IZV A;  1CSY A;  4XZ0 A;  1QG1 E;  1BF5 A;  5DC9 A;  3PJP A;  2IUH A;  3OV1 A;  2HDX A;  1OPK A;  4P9Z A;  2PLE A;  4L1B B;  2BBU A;  4OHE A;  5EEQ A;  2IUI A;  1D1Z A;  1IJR A;  3WA4 A;  1SPS A;  1O4E A;  2EYV A;  4DGP A;  2H5K A;  3NHN A;  2PNA A;  2CS0 A;  4K45 A;  1BFI A;  1Y1U A;  2RVF A;  1A1E A;  1O48 A;  1FU5 A;  2MRJ A;  2QMS A;  1LUI A;  1FYR A;  1CWD L;  2EO3 A;  2C0O A;  5EHP A;  1O47 A;  3BUM B;  3VS0 A;  3CWG A;  1O4L A;  1RJA A;  2HCK A;  1JU5 A;  2RMX A;  5DC0 B;  2HUW A;  1JYU A;  3BUW B;  1LKL A;  4JGH A;  3UYO A;  1BHH B;  5GJH A;  1LUK A;  2Y3A B;  1O4M A;  1ZFP E;  4H1O A;  4M4Z A;  4FBN A;  3KFJ A;  3CXL A;  2EKX A;  4FL2 A;  4K2R A;  1BFJ A;  2OQ1 A;  1O44 A;  1KA6 A;  1A1A A;  4P9V A;  3US4 A;  2C0I A;  3EAC A;  1NZV A;  3VRY A;  2YSX A;  1CSZ A;  2CIA A;  1LUN A;  4EY0 A;  4F5A A;  4U1P A;  2OZO A;  3HCK A;  1BLK A;  3S8N A;  1AD5 A;  2ETZ A;  2HMH A;  4A4B A;  1O4H A;  2FO0 A;  3TL0 A;  1LUM A;  1MIL A;  4LUE A;  1FHS A;  1P13 A;  2RSY A;  4GWF A;  2Y1M A;  1IS0 A;  1O4D A;  1SHB A;  4EIH A;  1BMB A;  2CR4 A;  3N84 A;  1RQQ C;  3VRP A;  2AOB A;  3TKZ A;  2LQN A;  1O4N A;  3CD3 A;  1AYD A;  2SRC A;  1PIC A;  1O4C A;  1KA7 A;  1O4R A;  1X0N A;  5EHR A;  3VRR A;  1FMK A;  1R1Q A;  4NWF A;  2EYZ A;  2XP1 A;  5EEL A;  3GXX A;  5KAZ A;  4QSY A;  5CDW A;  1MW4 A;  3VS5 A;  4WWQ A;  3BUN B;  3OB2 B;  2L6K A;  3PS5 A;  4F5B A;  2H46 E;  1BHH A;  1JYQ A;  1CWE A;  1O4K A;  3N7Y A;  4OHL A;  1AYA A;  3BKB A;  1WQU A;  2IUG A;  3VRN A;  1G83 A;  3VS6 A;  1NRV A;  1O4J A;  4JEG A;  2CBL A;  1X27 A;  2DX0 A;  2CRH A;  4E68 A;  2L3T A;  1SKJ A;  4H34 A;  1A1C A;  1AYB A;  4FL3 A;  2YU7 A;  1OO4 A;  3S8O A;  4A4C A;  2B3O A;  3VS1 A;  1O4A A;  4K44 A;  3UF4 A;  3VRQ A;  1LCJ A;  4NWG A;  2MC1 A;  1YVH A;  1X6C A;  1JYR A;  1AOU F;  1UUR A;  1HCS B;  1OO3 A;  1UUS A;  5J3X A;  1A81 A;  2L4K A;  1AYC A;  3PQZ A;  5AXI A;  1YVL A;  1Z3K A;  1NZL A;  4DGX A;  4JE4 A;  2EYY A;  4K11 A;  4OHI A;  1O41 A;  4OHH A;  1A07 A;  3GXW A;  3VS4 A;  1FBV A;  1BG1 A;  1FU6 A;  3OVE A;  2DVJ A;  3VRO A;  5HKW A;  1O4B A;  3N8M A;  1BLJ A;  3PSJ A;  2AUG A;  1HCT B;  4GL9 E;  2Y1N A;  2C0T A;  3HHM B;  5EG3 B;  5I6V A;  2LNW A;  3IMJ A;  1SHA A;  1O43 A;  2LCT A;  3T04 A;  1AOT F;  1O4G A;  2MQI A;  2JYQ A;  2MRK A;  1O4O A;  2DLZ A;  2C9W A;  1XA6 A;  2CI8 A;  3PFV A;  2FCI A;  2PLD A;  3MXY A;  3IN7 A;  4GPL B;  2SHP A;  5HKZ A;  4E93 A;  2H8H A;  2EL8 A;  1FBZ A;  1SHD A; 
#chains in the Genus database with same CATH topology
 1TZE E;  1QCF A;  2DM0 A;  3BUX B;  1O4F A;  1A09 A;  3IN8 A;  5GJI A;  2MK2 A;  3QWX X;  2CI9 A;  1M27 A;  1K9A A;  1R1P A;  1A08 A;  1Y57 A;  2KNO A;  3VS3 A;  3IMD A;  2AOA A;  1O45 A;  3MAZ A;  1CJ1 A;  3QWY A;  4U17 A;  1O49 A;  5AUL A;  5DF6 A;  4OHD A;  2LRA A;  1BKM A;  1BKL A;  2HDV A;  3CBL A;  1F1W A;  4F59 A;  1AB2 A;  1O4P A;  2DCR A;  2LNX A;  1OPL A;  1TCE A;  5D0J A;  1I3Z A;  3PLF B;  2ROR A;  1SPR A;  3K2T A;  5IBM A;  3VS7 A;  5DC4 A;  1B47 A;  3OP0 A;  2ECD A;  1BM2 A;  3OB1 B;  1GRI A;  5IBS A;  1JWO A;  1O42 A;  2K79 B;  3C7I A;  3M7F A;  4D8K A;  2GSB A;  4ROJ A;  1R1S A;  3VS2 A;  1KC2 A;  1A1B A;  2K7A B;  2KK6 A;  4LUD A;  3GQI B;  1BHF A;  3S8L A;  2GE9 A;  3BUO B;  1F2F A;  1M61 A;  3EAZ A;  3PSK A;  3VRZ A;  3MXC A;  2ABL A;  5HKY A;  2EU0 A;  3VGO A;  1O46 A;  1O4I A;  3K2M A;  1GHU A;  1QAD A;  1LKK A;  2PTK A;  1O4Q A;  4X6S A;  1LCK A;  2DLY A;  2EO6 A;  3LYV A;  4TZI A;  5BO4 A;  2VIF A;  4XZ1 A;  3ZNI A;  1D4T A;  2LQW A;  2EOB A;  1D4W A;  3S9K A;  1RPY A;  3HIZ B;  1H9O A;  2PNB A;  1KSW A;  2IZV A;  1CSY A;  4XZ0 A;  1QG1 E;  1BF5 A;  5DC9 A;  3PJP A;  2IUH A;  3OV1 A;  2HDX A;  1OPK A;  4P9Z A;  2PLE A;  4L1B B;  2BBU A;  4OHE A;  5EEQ A;  2IUI A;  1D1Z A;  1IJR A;  3WA4 A;  1SPS A;  1O4E A;  2EYV A;  4DGP A;  2H5K A;  3NHN A;  2PNA A;  2CS0 A;  4K45 A;  1BFI A;  1Y1U A;  2RVF A;  1A1E A;  1O48 A;  1FU5 A;  2MRJ A;  2QMS A;  1LUI A;  1FYR A;  1CWD L;  2EO3 A;  2C0O A;  5EHP A;  1O47 A;  3BUM B;  3VS0 A;  3CWG A;  1O4L A;  1RJA A;  2HCK A;  1JU5 A;  2RMX A;  5DC0 B;  2HUW A;  1JYU A;  3BUW B;  1LKL A;  4JGH A;  3UYO A;  1BHH B;  5GJH A;  1LUK A;  2Y3A B;  1O4M A;  1ZFP E;  4H1O A;  4M4Z A;  4FBN A;  3KFJ A;  3CXL A;  2EKX A;  4FL2 A;  4K2R A;  1BFJ A;  2OQ1 A;  1O44 A;  1KA6 A;  1A1A A;  4P9V A;  3US4 A;  2C0I A;  3EAC A;  1NZV A;  3VRY A;  2YSX A;  1CSZ A;  2CIA A;  1LUN A;  4EY0 A;  4F5A A;  4U1P A;  2OZO A;  3HCK A;  1BLK A;  3S8N A;  1AD5 A;  2ETZ A;  2HMH A;  4A4B A;  1O4H A;  2FO0 A;  3TL0 A;  1LUM A;  1MIL A;  4LUE A;  1FHS A;  1P13 A;  2RSY A;  4GWF A;  2Y1M A;  1IS0 A;  1O4D A;  1SHB A;  4EIH A;  1BMB A;  2CR4 A;  3N84 A;  1RQQ C;  3VRP A;  2AOB A;  3TKZ A;  2LQN A;  1O4N A;  3CD3 A;  1AYD A;  2SRC A;  1PIC A;  1O4C A;  1KA7 A;  1O4R A;  1X0N A;  5EHR A;  3VRR A;  1FMK A;  1R1Q A;  4NWF A;  2EYZ A;  2XP1 A;  5EEL A;  3GXX A;  5KAZ A;  4QSY A;  5CDW A;  1MW4 A;  3VS5 A;  4WWQ A;  3BUN B;  3OB2 B;  2L6K A;  3PS5 A;  4F5B A;  2H46 E;  1BHH A;  1JYQ A;  1CWE A;  1O4K A;  3N7Y A;  4OHL A;  1AYA A;  3BKB A;  1WQU A;  2IUG A;  3VRN A;  1G83 A;  3VS6 A;  1NRV A;  1O4J A;  2KGY A;  2CBL A;  4JEG A;  1X27 A;  2DX0 A;  2CRH A;  4E68 A;  2L3T A;  1SKJ A;  4H34 A;  1A1C A;  1AYB A;  4FL3 A;  2YU7 A;  1OO4 A;  3S8O A;  4A4C A;  2B3O A;  3VS1 A;  1O4A A;  4K44 A;  3UF4 A;  3VRQ A;  1LCJ A;  4NWG A;  2MC1 A;  1YVH A;  1X6C A;  1JYR A;  1AOU F;  1UUR A;  1HCS B;  1OO3 A;  1UUS A;  5J3X A;  1A81 A;  2L4K A;  1AYC A;  3PQZ A;  5AXI A;  1YVL A;  1Z3K A;  1NZL A;  4DGX A;  4JE4 A;  2EYY A;  4K11 A;  4OHI A;  1O41 A;  4OHH A;  1A07 A;  3GXW A;  3VS4 A;  1FBV A;  1BG1 A;  1FU6 A;  3OVE A;  2DVJ A;  3VRO A;  5HKW A;  1O4B A;  3N8M A;  1BLJ A;  3PSJ A;  2AUG A;  1HCT B;  4GL9 E;  2Y1N A;  2C0T A;  3HHM B;  5EG3 B;  5I6V A;  2LNW A;  3IMJ A;  1SHA A;  1O43 A;  2LCT A;  3T04 A;  1AOT F;  1O4G A;  2MQI A;  2JYQ A;  2MRK A;  1O4O A;  2DLZ A;  2C9W A;  1XA6 A;  2CI8 A;  3PFV A;  2FCI A;  2PLD A;  3MXY A;  3IN7 A;  4GPL B;  2SHP A;  5HKZ A;  4E93 A;  2H8H A;  2EL8 A;  1FBZ A;  1SHD A; 
#chains in the Genus database with same CATH homology
 1TZE E;  1QCF A;  2DM0 A;  3BUX B;  1O4F A;  1A09 A;  3IN8 A;  5GJI A;  2MK2 A;  3QWX X;  2CI9 A;  1M27 A;  1K9A A;  1R1P A;  1A08 A;  1Y57 A;  2KNO A;  3VS3 A;  3IMD A;  2AOA A;  1O45 A;  3MAZ A;  1CJ1 A;  3QWY A;  4U17 A;  1O49 A;  5AUL A;  5DF6 A;  4OHD A;  1BKM A;  1BKL A;  2HDV A;  3CBL A;  1F1W A;  4F59 A;  1AB2 A;  1O4P A;  2DCR A;  2LNX A;  1OPL A;  1TCE A;  5D0J A;  1I3Z A;  3PLF B;  2ROR A;  1SPR A;  5IBM A;  3VS7 A;  5DC4 A;  1B47 A;  3OP0 A;  2ECD A;  1BM2 A;  3OB1 B;  1GRI A;  5IBS A;  1JWO A;  1O42 A;  2K79 B;  3C7I A;  3M7F A;  4D8K A;  2GSB A;  4ROJ A;  1R1S A;  3VS2 A;  1KC2 A;  1A1B A;  2K7A B;  2KK6 A;  4LUD A;  3GQI B;  1BHF A;  3S8L A;  2GE9 A;  3BUO B;  1F2F A;  1M61 A;  3EAZ A;  3PSK A;  3VRZ A;  3MXC A;  2ABL A;  5HKY A;  2EU0 A;  3VGO A;  1O46 A;  1O4I A;  3K2M A;  1GHU A;  1QAD A;  1LKK A;  2PTK A;  1O4Q A;  4X6S A;  1LCK A;  2DLY A;  2EO6 A;  4TZI A;  5BO4 A;  2VIF A;  4XZ1 A;  3ZNI A;  1D4T A;  2LQW A;  2EOB A;  1D4W A;  3S9K A;  1RPY A;  3HIZ B;  1H9O A;  2PNB A;  1KSW A;  2IZV A;  1CSY A;  4XZ0 A;  1QG1 E;  1BF5 A;  5DC9 A;  3PJP A;  2IUH A;  3OV1 A;  2HDX A;  1OPK A;  4P9Z A;  2PLE A;  4L1B B;  2BBU A;  4OHE A;  5EEQ A;  2IUI A;  1D1Z A;  1IJR A;  3WA4 A;  1SPS A;  1O4E A;  2EYV A;  4DGP A;  2H5K A;  3NHN A;  2PNA A;  2CS0 A;  4K45 A;  1BFI A;  1Y1U A;  2RVF A;  1A1E A;  1O48 A;  1FU5 A;  2MRJ A;  2QMS A;  1LUI A;  1FYR A;  1CWD L;  2EO3 A;  2C0O A;  5EHP A;  1O47 A;  3BUM B;  3VS0 A;  3CWG A;  1O4L A;  1RJA A;  2HCK A;  1JU5 A;  2RMX A;  5DC0 B;  2HUW A;  1JYU A;  3BUW B;  1LKL A;  4JGH A;  3UYO A;  1BHH B;  5GJH A;  1LUK A;  2Y3A B;  1O4M A;  1ZFP E;  4H1O A;  4M4Z A;  4FBN A;  3KFJ A;  3CXL A;  2EKX A;  4FL2 A;  4K2R A;  1BFJ A;  2OQ1 A;  1O44 A;  1KA6 A;  1A1A A;  4P9V A;  3US4 A;  2C0I A;  3EAC A;  1NZV A;  3VRY A;  2YSX A;  1CSZ A;  2CIA A;  1LUN A;  4EY0 A;  4F5A A;  4U1P A;  2OZO A;  3HCK A;  1BLK A;  3S8N A;  1AD5 A;  2ETZ A;  2HMH A;  4A4B A;  1O4H A;  2FO0 A;  3TL0 A;  1LUM A;  1MIL A;  4LUE A;  1FHS A;  1P13 A;  2RSY A;  4GWF A;  2Y1M A;  1IS0 A;  1O4D A;  1SHB A;  4EIH A;  1BMB A;  2CR4 A;  3N84 A;  1RQQ C;  3VRP A;  2AOB A;  3TKZ A;  2LQN A;  1O4N A;  3CD3 A;  1AYD A;  2SRC A;  1PIC A;  1O4C A;  1KA7 A;  1O4R A;  1X0N A;  5EHR A;  3VRR A;  1FMK A;  1R1Q A;  4NWF A;  2EYZ A;  2XP1 A;  5EEL A;  3GXX A;  5KAZ A;  4QSY A;  5CDW A;  1MW4 A;  3VS5 A;  4WWQ A;  3BUN B;  3OB2 B;  2L6K A;  3PS5 A;  4F5B A;  2H46 E;  1BHH A;  1JYQ A;  1CWE A;  1O4K A;  3N7Y A;  4OHL A;  1AYA A;  3BKB A;  1WQU A;  2IUG A;  3VRN A;  1G83 A;  3VS6 A;  1NRV A;  1O4J A;  4JEG A;  2CBL A;  1X27 A;  2DX0 A;  2CRH A;  4E68 A;  2L3T A;  1SKJ A;  4H34 A;  1A1C A;  1AYB A;  4FL3 A;  2YU7 A;  1OO4 A;  3S8O A;  4A4C A;  2B3O A;  3VS1 A;  1O4A A;  4K44 A;  3UF4 A;  3VRQ A;  1LCJ A;  4NWG A;  2MC1 A;  1YVH A;  1X6C A;  1JYR A;  1AOU F;  1UUR A;  1HCS B;  1OO3 A;  1UUS A;  5J3X A;  1A81 A;  2L4K A;  1AYC A;  3PQZ A;  5AXI A;  1YVL A;  1Z3K A;  1NZL A;  4DGX A;  4JE4 A;  2EYY A;  4K11 A;  4OHI A;  1O41 A;  4OHH A;  1A07 A;  3GXW A;  3VS4 A;  1FBV A;  1BG1 A;  1FU6 A;  3OVE A;  2DVJ A;  3VRO A;  5HKW A;  1O4B A;  3N8M A;  1BLJ A;  3PSJ A;  2AUG A;  1HCT B;  4GL9 E;  2Y1N A;  2C0T A;  3HHM B;  5EG3 B;  5I6V A;  2LNW A;  3IMJ A;  1SHA A;  1O43 A;  2LCT A;  3T04 A;  1AOT F;  1O4G A;  2MQI A;  2JYQ A;  2MRK A;  1O4O A;  2DLZ A;  2C9W A;  1XA6 A;  2CI8 A;  3PFV A;  2FCI A;  2PLD A;  3MXY A;  3IN7 A;  4GPL B;  2SHP A;  5HKZ A;  4E93 A;  2H8H A;  2EL8 A;  1FBZ A;  1SHD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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