1O4HA

Crystal structure of sh2 in complex with ru79072.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 27
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4hA00
3HIZB 3PSJA 4GPLB 2DCRA 2EU0A 2FO0A 2JYQA 3CD3A 3ZNIA 5DC9A 3VGOA 1CWEA 2HDXA 1LUIA 4A4CA 1O49A 3VRYA 5DC4A 1D1ZA 3OB2B 2C0IA 3VRPA 3MXCA 1WQUA 1BHHA 5KAZA 2IUGA 1OO4A 4GWFA 4K45A 4LUDA 5DC0B 3VS0A 1AD5A 3VS3A 5BO4A 1D4WA 4NWFA 4WWQA 2EO6A 1O4CA 2AUGA 3VS5A 1AYAA 1JU5A 2LQWA 1R1QA 3TKZA 2PNBA 3GXXA 2HUWA 1O4HA 4H1OA 1HCTB 3PQZA 1SPRA 2EKXA 1GHUA 1AYCA 2CRHA 1X0NA 1I3ZA 1AYBA 3KFJA 2RSYA 3CXLA 2HDVA 1QG1E 1O4MA 4DGPA 1O42A 2DM0A 3N84A 2CR4A 2CIAA 3EACA 2AOBA 1SPSA 5GJHA 3MAZA 1BM2A 4K11A 2SHPA 1K9AA 1A1AA 1LKKA 1X6CA 4EIHA 3BUMB 5GJIA 1Y1UA 1YVHA 3VS2A 2EOBA 1FBVA 2CI9A 4NWGA 4FL3A 1X27A 1Y57A 2GE9A 3PS5A 5EHRA 1PICA 1XA6A 4L1BB 1GRIA 1O4JA 1G83A 3BKBA 4QSYA 1MW4A 1O4EA 3N8MA 3OP0A 1LKLA 2DX0A 5IBSA 1O4RA 2C0OA 3US4A 3VRRA 3QWXX 1O45A 2DVJA 2CS0A 3VROA 1OPKA 1A1BA 4E68A 1ZFPE 1R1SA 1O4FA 2MQIA 3IN7A 1BKMA 1SHDA 2EYVA 2YSXA 1O4GA 5J3XA 5I6VA 2MK2A 2K7AB 2ECDA 1BF5A 3BUWB 1NZVA 2OQ1A 3CBLA 3CWGA 4OHIA 3MXYA 1LUNA 1D4TA 4GL9E 2AOAA 3HCKA 4M4ZA 3PJPA 5EHPA 5HKYA 1O4OA 1O43A 1O4DA 2ETZA 5EG3B 1QCFA 1NZLA 2BBUA 2Y1MA 3QWYA 1HCSB 1SHBA 1O4AA 3IN8A 1RQQC 2H46E 1IS0A 4JGHA 3S8LA 3PSKA 1OPLA 4OHDA 1CJ1A 2L6KA 3UF4A 2GSBA 5DF6A 1M27A 3T04A 2HMHA 4JEGA 1BFJA 3VS6A 3TL0A 2Y3AB 1A1CA 1BG1A 2SRCA 2K79B 2FCIA 3OB1B 1QADA 1FYRA 1O4PA 5HKWA 3EAZA 3HHMB 2C9WA 2RORA 1O46A 3S9KA 1BKLA 1SKJA 4XZ1A 4K44A 1LCJA 1O4IA 2LNXA 4H34A 1O4KA 4F5AA 1A08A 1FU5A 2HCKA 5IBMA 1Z3KA 2EYZA 1F2FA 4E93A 1A81A 1FU6A 2ABLA 5HKZA 1KA6A 1BLJA 4OHEA 2EL8A 3VRNA 4LUEA 3PLFB 1B47A 3VS1A 1UUSA 2XP1A 1AB2A 3GXWA 4A4BA 3NHNA 1F1WA 1BMBA 3GQIB 3BUNB 3IMJA 3VS4A 2B3OA 1O4BA 4OHHA 1O41A 1FMKA 1SHAA 1A07A 2C0TA 3OVEA 1O4QA 1YVLA 2CBLA 3C7IA 4EY0A 2LCTA 1RPYA 2QMSA 4FBNA 4DGXA 3OV1A 1BHFA 3BUXB 1AYDA 1O4NA 4P9ZA 1TZEE 3WA4A 2H5KA 1R1PA 1LUKA 1O47A 2LNWA 1FBZA 1BFIA 4U17A 3UYOA 1JYRA 1MILA 1H9OA 2IZVA 2RMXA 1O4LA 1BLKA 3VRQA 5EELA 1OO3A 3K2MA 3M7FA 4JE4A 1A09A 2IUHA 2PNAA 3VS7A 1CSYA 1KA7A 2CI8A 3PFVA 2YU7A 2DLZA 1A1EA 1RJAA 4D8KA 1AOUF 1M61A 5AXIA 1JWOA 2Y1NA 2MRJA 2OZOA 2EO3A 1CWDL 3N7YA 1TCEA 4ROJA 2MRKA 4U1PA 3S8OA 3BUOB 5D0JA 2EYYA 1CSZA 1JYQA 3VRZA 4OHLA 2LQNA 1BHHB 2KNOA 1P13A 1LCKA 4XZ0A 1O48A 2L3TA 5EEQA 2H8HA 4X6SA 3IMDA 4F5BA 4TZIA 2KK6A 2VIFA 5AULA 1NRVA 4F59A 1JYUA 1KSWA 1O44A 1UURA 2MC1A 2PLDA 5CDWA 4P9VA 2PTKA 1KC2A 3S8NA 2IUIA 1AOTF 2PLEA 1FHSA 4FL2A 1IJRA 2RVFA 1LUMA 2L4KA 2DLYA 4K2RA
chains in the Genus database with same CATH superfamily
3HIZB 3PSJA 4GPLB 2DCRA 2EU0A 2FO0A 2JYQA 3CD3A 3ZNIA 5DC9A 3VGOA 1CWEA 2HDXA 1LUIA 4A4CA 1O49A 3VRYA 5DC4A 1D1ZA 3OB2B 2C0IA 3VRPA 3MXCA 1WQUA 1BHHA 5KAZA 2LRAA 2IUGA 1OO4A 4GWFA 4K45A 4LUDA 5DC0B 3VS0A 1AD5A 3VS3A 5BO4A 1D4WA 4NWFA 4WWQA 2EO6A 1O4CA 2AUGA 3VS5A 1AYAA 1JU5A 2LQWA 1R1QA 3TKZA 2PNBA 3GXXA 2HUWA 1O4HA 4H1OA 1HCTB 3PQZA 1SPRA 2EKXA 1GHUA 1AYCA 2CRHA 1X0NA 1I3ZA 1AYBA 3KFJA 2RSYA 3CXLA 2HDVA 1QG1E 1O4MA 4DGPA 1O42A 2DM0A 3N84A 2CR4A 2CIAA 3EACA 2AOBA 1SPSA 5GJHA 3MAZA 1BM2A 4K11A 2SHPA 1K9AA 1A1AA 1LKKA 1X6CA 4EIHA 3BUMB 5GJIA 1Y1UA 1YVHA 3VS2A 3LYVA 2EOBA 1FBVA 2CI9A 4NWGA 4FL3A 1X27A 1Y57A 2GE9A 3PS5A 5EHRA 1PICA 1XA6A 4L1BB 1GRIA 1O4JA 1G83A 3BKBA 4QSYA 1MW4A 1O4EA 3N8MA 3OP0A 1LKLA 2DX0A 5IBSA 1O4RA 2C0OA 3US4A 3VRRA 3QWXX 1O45A 2DVJA 2CS0A 3VROA 1OPKA 1A1BA 4E68A 1ZFPE 1R1SA 1O4FA 2MQIA 3IN7A 1BKMA 1SHDA 2EYVA 2YSXA 1O4GA 5J3XA 5I6VA 2MK2A 2K7AB 2ECDA 1BF5A 3BUWB 1NZVA 2OQ1A 3CBLA 3CWGA 4OHIA 3MXYA 1LUNA 1D4TA 4GL9E 2AOAA 3HCKA 4M4ZA 3PJPA 5EHPA 5HKYA 1O4OA 1O43A 1O4DA 2ETZA 5EG3B 1QCFA 1NZLA 2BBUA 2Y1MA 3QWYA 1HCSB 1SHBA 1O4AA 3IN8A 1RQQC 2H46E 1IS0A 4JGHA 3S8LA 3PSKA 1OPLA 4OHDA 1CJ1A 2L6KA 3UF4A 2GSBA 5DF6A 1M27A 3T04A 2HMHA 4JEGA 1BFJA 3VS6A 3TL0A 2Y3AB 3K2TA 1A1CA 1BG1A 2SRCA 2K79B 2FCIA 3OB1B 1QADA 1FYRA 1O4PA 5HKWA 3EAZA 3HHMB 2C9WA 2RORA 1O46A 3S9KA 1BKLA 1SKJA 4XZ1A 4K44A 1LCJA 1O4IA 2LNXA 4H34A 1O4KA 4F5AA 1A08A 1FU5A 2HCKA 5IBMA 1Z3KA 2EYZA 1F2FA 4E93A 1A81A 1FU6A 2ABLA 5HKZA 1KA6A 1BLJA 4OHEA 2EL8A 3VRNA 4LUEA 3PLFB 1B47A 3VS1A 1UUSA 2XP1A 1AB2A 3GXWA 4A4BA 3NHNA 1F1WA 1BMBA 3GQIB 3BUNB 3IMJA 3VS4A 2B3OA 1O4BA 4OHHA 1O41A 1FMKA 1SHAA 1A07A 2C0TA 3OVEA 1O4QA 1YVLA 2CBLA 3C7IA 4EY0A 2LCTA 1RPYA 2QMSA 4FBNA 4DGXA 3OV1A 1BHFA 3BUXB 1AYDA 1O4NA 4P9ZA 1TZEE 3WA4A 2H5KA 1R1PA 1LUKA 1O47A 2LNWA 1FBZA 1BFIA 4U17A 3UYOA 1JYRA 1MILA 1H9OA 2IZVA 2RMXA 1O4LA 1BLKA 3VRQA 2KGYA 5EELA 1OO3A 3K2MA 3M7FA 4JE4A 1A09A 2IUHA 2PNAA 3VS7A 1CSYA 1KA7A 2CI8A 3PFVA 2YU7A 2DLZA 1A1EA 1RJAA 4D8KA 1AOUF 1M61A 5AXIA 1JWOA 2Y1NA 2MRJA 2OZOA 2EO3A 1CWDL 3N7YA 1TCEA 4ROJA 2MRKA 4U1PA 3S8OA 3BUOB 5D0JA 2EYYA 1CSZA 1JYQA 3VRZA 4OHLA 2LQNA 1BHHB 2KNOA 1P13A 1LCKA 4XZ0A 1O48A 2L3TA 5EEQA 2H8HA 4X6SA 3IMDA 4F5BA 4TZIA 2KK6A 2VIFA 5AULA 1NRVA 4F59A 1JYUA 1KSWA 1O44A 1UURA 2MC1A 2PLDA 5CDWA 4P9VA 2PTKA 1KC2A 3S8NA 2IUIA 1AOTF 2PLEA 1FHSA 4FL2A 1IJRA 2RVFA 1LUMA 2L4KA 2DLYA 4K2RA
chains in the Genus database with same CATH topology
3HIZB 3PSJA 4GPLB 2DCRA 2EU0A 2FO0A 2JYQA 3CD3A 3ZNIA 5DC9A 3VGOA 1CWEA 2HDXA 1LUIA 4A4CA 1O49A 3VRYA 5DC4A 1D1ZA 3OB2B 2C0IA 3VRPA 3MXCA 1WQUA 1BHHA 5KAZA 2IUGA 1OO4A 4GWFA 4K45A 4LUDA 5DC0B 3VS0A 1AD5A 3VS3A 5BO4A 1D4WA 4NWFA 4WWQA 2EO6A 1O4CA 2AUGA 3VS5A 1AYAA 1JU5A 2LQWA 1R1QA 3TKZA 2PNBA 3GXXA 2HUWA 1O4HA 4H1OA 1HCTB 3PQZA 1SPRA 2EKXA 1GHUA 1AYCA 2CRHA 1X0NA 1I3ZA 1AYBA 3KFJA 2RSYA 3CXLA 2HDVA 1QG1E 1O4MA 4DGPA 1O42A 2DM0A 3N84A 2CR4A 2CIAA 3EACA 2AOBA 1SPSA 5GJHA 3MAZA 1BM2A 4K11A 2SHPA 1K9AA 1A1AA 1LKKA 1X6CA 4EIHA 3BUMB 5GJIA 1Y1UA 1YVHA 3VS2A 2EOBA 1FBVA 2CI9A 4NWGA 4FL3A 1X27A 1Y57A 2GE9A 3PS5A 5EHRA 1PICA 1XA6A 4L1BB 1GRIA 1O4JA 1G83A 3BKBA 4QSYA 1MW4A 1O4EA 3N8MA 3OP0A 1LKLA 2DX0A 5IBSA 1O4RA 2C0OA 3US4A 3VRRA 3QWXX 1O45A 2DVJA 2CS0A 3VROA 1OPKA 1A1BA 4E68A 1ZFPE 1R1SA 1O4FA 2MQIA 3IN7A 1BKMA 1SHDA 2EYVA 2YSXA 1O4GA 5J3XA 5I6VA 2MK2A 2K7AB 2ECDA 1BF5A 3BUWB 1NZVA 2OQ1A 3CBLA 3CWGA 4OHIA 3MXYA 1LUNA 1D4TA 4GL9E 2AOAA 3HCKA 4M4ZA 3PJPA 5EHPA 5HKYA 1O4OA 1O43A 1O4DA 2ETZA 5EG3B 1QCFA 1NZLA 2BBUA 2Y1MA 3QWYA 1HCSB 1SHBA 1O4AA 3IN8A 1RQQC 2H46E 1IS0A 4JGHA 3S8LA 3PSKA 1OPLA 4OHDA 1CJ1A 2L6KA 3UF4A 2GSBA 5DF6A 1M27A 3T04A 2HMHA 4JEGA 1BFJA 3VS6A 3TL0A 2Y3AB 1A1CA 1BG1A 2SRCA 2K79B 2FCIA 3OB1B 1QADA 1FYRA 1O4PA 5HKWA 3EAZA 3HHMB 2C9WA 2RORA 1O46A 3S9KA 1BKLA 1SKJA 4XZ1A 4K44A 1LCJA 1O4IA 2LNXA 4H34A 1O4KA 4F5AA 1A08A 1FU5A 2HCKA 5IBMA 1Z3KA 2EYZA 1F2FA 4E93A 1A81A 1FU6A 2ABLA 5HKZA 1KA6A 1BLJA 4OHEA 2EL8A 3VRNA 4LUEA 3PLFB 1B47A 3VS1A 1UUSA 2XP1A 1AB2A 3GXWA 4A4BA 3NHNA 1F1WA 1BMBA 3GQIB 3BUNB 3IMJA 3VS4A 2B3OA 1O4BA 4OHHA 1O41A 1FMKA 1SHAA 1A07A 2C0TA 3OVEA 1O4QA 1YVLA 2CBLA 3C7IA 4EY0A 2LCTA 1RPYA 2QMSA 4FBNA 4DGXA 3OV1A 1BHFA 3BUXB 1AYDA 1O4NA 4P9ZA 1TZEE 3WA4A 2H5KA 1R1PA 1LUKA 1O47A 2LNWA 1FBZA 1BFIA 4U17A 3UYOA 1JYRA 1MILA 1H9OA 2IZVA 2RMXA 1O4LA 1BLKA 3VRQA 5EELA 1OO3A 3K2MA 3M7FA 4JE4A 1A09A 2IUHA 2PNAA 3VS7A 1CSYA 1KA7A 2CI8A 3PFVA 2YU7A 2DLZA 1A1EA 1RJAA 4D8KA 1AOUF 1M61A 5AXIA 1JWOA 2Y1NA 2MRJA 2OZOA 2EO3A 1CWDL 3N7YA 1TCEA 4ROJA 2MRKA 4U1PA 3S8OA 3BUOB 5D0JA 2EYYA 1CSZA 1JYQA 3VRZA 4OHLA 2LQNA 1BHHB 2KNOA 1P13A 1LCKA 4XZ0A 1O48A 2L3TA 5EEQA 2H8HA 4X6SA 3IMDA 4F5BA 4TZIA 2KK6A 2VIFA 5AULA 1NRVA 4F59A 1JYUA 1KSWA 1O44A 1UURA 2MC1A 2PLDA 5CDWA 4P9VA 2PTKA 1KC2A 3S8NA 2IUIA 1AOTF 2PLEA 1FHSA 4FL2A 1IJRA 2RVFA 1LUMA 2L4KA 2DLYA 4K2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HIZ B;  3PSJ A;  4GPL B;  2DCR A;  2EU0 A;  2FO0 A;  2JYQ A;  3CD3 A;  3ZNI A;  5DC9 A;  3VGO A;  1CWE A;  2HDX A;  1LUI A;  4A4C A;  1O49 A;  3VRY A;  5DC4 A;  1D1Z A;  3OB2 B;  2C0I A;  3VRP A;  3MXC A;  1WQU A;  1BHH A;  5KAZ A;  2IUG A;  1OO4 A;  4GWF A;  4K45 A;  4LUD A;  5DC0 B;  3VS0 A;  1AD5 A;  3VS3 A;  5BO4 A;  1D4W A;  4NWF A;  4WWQ A;  2EO6 A;  1O4C A;  2AUG A;  3VS5 A;  1AYA A;  1JU5 A;  2LQW A;  1R1Q A;  3TKZ A;  2PNB A;  3GXX A;  2HUW A;  1O4H A;  4H1O A;  1HCT B;  3PQZ A;  1SPR A;  2EKX A;  1GHU A;  1AYC A;  2CRH A;  1X0N A;  1I3Z A;  1AYB A;  3KFJ A;  2RSY A;  3CXL A;  2HDV A;  1QG1 E;  1O4M A;  4DGP A;  1O42 A;  2DM0 A;  3N84 A;  2CR4 A;  2CIA A;  3EAC A;  2AOB A;  1SPS A;  5GJH A;  3MAZ A;  1BM2 A;  4K11 A;  2SHP A;  1K9A A;  1A1A A;  1LKK A;  1X6C A;  4EIH A;  3BUM B;  5GJI A;  1Y1U A;  1YVH A;  3VS2 A;  2EOB A;  1FBV A;  2CI9 A;  4NWG A;  4FL3 A;  1X27 A;  1Y57 A;  2GE9 A;  3PS5 A;  5EHR A;  1PIC A;  1XA6 A;  4L1B B;  1GRI A;  1O4J A;  1G83 A;  3BKB A;  4QSY A;  1MW4 A;  1O4E A;  3N8M A;  3OP0 A;  1LKL A;  2DX0 A;  5IBS A;  1O4R A;  2C0O A;  3US4 A;  3VRR A;  3QWX X;  1O45 A;  2DVJ A;  2CS0 A;  3VRO A;  1OPK A;  1A1B A;  4E68 A;  1ZFP E;  1R1S A;  1O4F A;  2MQI A;  3IN7 A;  1BKM A;  1SHD A;  2EYV A;  2YSX A;  1O4G A;  5J3X A;  5I6V A;  2MK2 A;  2K7A B;  2ECD A;  1BF5 A;  3BUW B;  1NZV A;  2OQ1 A;  3CBL A;  3CWG A;  4OHI A;  3MXY A;  1LUN A;  1D4T A;  4GL9 E;  2AOA A;  3HCK A;  4M4Z A;  3PJP A;  5EHP A;  5HKY A;  1O4O A;  1O43 A;  1O4D A;  2ETZ A;  5EG3 B;  1QCF A;  1NZL A;  2BBU A;  2Y1M A;  3QWY A;  1HCS B;  1SHB A;  1O4A A;  3IN8 A;  1RQQ C;  2H46 E;  1IS0 A;  4JGH A;  3S8L A;  3PSK A;  1OPL A;  4OHD A;  1CJ1 A;  2L6K A;  3UF4 A;  2GSB A;  5DF6 A;  1M27 A;  3T04 A;  2HMH A;  4JEG A;  1BFJ A;  3VS6 A;  3TL0 A;  2Y3A B;  1A1C A;  1BG1 A;  2SRC A;  2K79 B;  2FCI A;  3OB1 B;  1QAD A;  1FYR A;  1O4P A;  5HKW A;  3EAZ A;  3HHM B;  2C9W A;  2ROR A;  1O46 A;  3S9K A;  1BKL A;  1SKJ A;  4XZ1 A;  4K44 A;  1LCJ A;  1O4I A;  2LNX A;  4H34 A;  1O4K A;  4F5A A;  1A08 A;  1FU5 A;  2HCK A;  5IBM A;  1Z3K A;  2EYZ A;  1F2F A;  4E93 A;  1A81 A;  1FU6 A;  2ABL A;  5HKZ A;  1KA6 A;  1BLJ A;  4OHE A;  2EL8 A;  3VRN A;  4LUE A;  3PLF B;  1B47 A;  3VS1 A;  1UUS A;  2XP1 A;  1AB2 A;  3GXW A;  4A4B A;  3NHN A;  1F1W A;  1BMB A;  3GQI B;  3BUN B;  3IMJ A;  3VS4 A;  2B3O A;  1O4B A;  4OHH A;  1O41 A;  1FMK A;  1SHA A;  1A07 A;  2C0T A;  3OVE A;  1O4Q A;  1YVL A;  2CBL A;  3C7I A;  4EY0 A;  2LCT A;  1RPY A;  2QMS A;  4FBN A;  4DGX A;  3OV1 A;  1BHF A;  3BUX B;  1AYD A;  1O4N A;  4P9Z A;  1TZE E;  3WA4 A;  2H5K A;  1R1P A;  1LUK A;  1O47 A;  2LNW A;  1FBZ A;  1BFI A;  4U17 A;  3UYO A;  1JYR A;  1MIL A;  1H9O A;  2IZV A;  2RMX A;  1O4L A;  1BLK A;  3VRQ A;  5EEL A;  1OO3 A;  3K2M A;  3M7F A;  4JE4 A;  1A09 A;  2IUH A;  2PNA A;  3VS7 A;  1CSY A;  1KA7 A;  2CI8 A;  3PFV A;  2YU7 A;  2DLZ A;  1A1E A;  1RJA A;  4D8K A;  1AOU F;  1M61 A;  5AXI A;  1JWO A;  2Y1N A;  2MRJ A;  2OZO A;  2EO3 A;  1CWD L;  3N7Y A;  1TCE A;  4ROJ A;  2MRK A;  4U1P A;  3S8O A;  3BUO B;  5D0J A;  2EYY A;  1CSZ A;  1JYQ A;  3VRZ A;  4OHL A;  2LQN A;  1BHH B;  2KNO A;  1P13 A;  1LCK A;  4XZ0 A;  1O48 A;  2L3T A;  5EEQ A;  2H8H A;  4X6S A;  3IMD A;  4F5B A;  4TZI A;  2KK6 A;  2VIF A;  5AUL A;  1NRV A;  4F59 A;  1JYU A;  1KSW A;  1O44 A;  1UUR A;  2MC1 A;  2PLD A;  5CDW A;  4P9V A;  2PTK A;  1KC2 A;  3S8N A;  2IUI A;  1AOT F;  2PLE A;  1FHS A;  4FL2 A;  1IJR A;  2RVF A;  1LUM A;  2L4K A;  2DLY A;  4K2R A; 
#chains in the Genus database with same CATH topology
 3HIZ B;  3PSJ A;  4GPL B;  2DCR A;  2EU0 A;  2FO0 A;  2JYQ A;  3CD3 A;  3ZNI A;  5DC9 A;  3VGO A;  1CWE A;  2HDX A;  1LUI A;  4A4C A;  1O49 A;  3VRY A;  5DC4 A;  1D1Z A;  3OB2 B;  2C0I A;  3VRP A;  3MXC A;  1WQU A;  1BHH A;  5KAZ A;  2LRA A;  2IUG A;  1OO4 A;  4GWF A;  4K45 A;  4LUD A;  5DC0 B;  3VS0 A;  1AD5 A;  3VS3 A;  5BO4 A;  1D4W A;  4NWF A;  4WWQ A;  2EO6 A;  1O4C A;  2AUG A;  3VS5 A;  1AYA A;  1JU5 A;  2LQW A;  1R1Q A;  3TKZ A;  2PNB A;  3GXX A;  2HUW A;  1O4H A;  4H1O A;  1HCT B;  3PQZ A;  1SPR A;  2EKX A;  1GHU A;  1AYC A;  2CRH A;  1X0N A;  1I3Z A;  1AYB A;  3KFJ A;  2RSY A;  3CXL A;  2HDV A;  1QG1 E;  1O4M A;  4DGP A;  1O42 A;  2DM0 A;  3N84 A;  2CR4 A;  2CIA A;  3EAC A;  2AOB A;  1SPS A;  5GJH A;  3MAZ A;  1BM2 A;  4K11 A;  2SHP A;  1K9A A;  1A1A A;  1LKK A;  1X6C A;  4EIH A;  3BUM B;  5GJI A;  1Y1U A;  1YVH A;  3VS2 A;  3LYV A;  2EOB A;  1FBV A;  2CI9 A;  4NWG A;  4FL3 A;  1X27 A;  1Y57 A;  2GE9 A;  3PS5 A;  5EHR A;  1PIC A;  1XA6 A;  4L1B B;  1GRI A;  1O4J A;  1G83 A;  3BKB A;  4QSY A;  1MW4 A;  1O4E A;  3N8M A;  3OP0 A;  1LKL A;  2DX0 A;  5IBS A;  1O4R A;  2C0O A;  3US4 A;  3VRR A;  3QWX X;  1O45 A;  2DVJ A;  2CS0 A;  3VRO A;  1OPK A;  1A1B A;  4E68 A;  1ZFP E;  1R1S A;  1O4F A;  2MQI A;  3IN7 A;  1BKM A;  1SHD A;  2EYV A;  2YSX A;  1O4G A;  5J3X A;  5I6V A;  2MK2 A;  2K7A B;  2ECD A;  1BF5 A;  3BUW B;  1NZV A;  2OQ1 A;  3CBL A;  3CWG A;  4OHI A;  3MXY A;  1LUN A;  1D4T A;  4GL9 E;  2AOA A;  3HCK A;  4M4Z A;  3PJP A;  5EHP A;  5HKY A;  1O4O A;  1O43 A;  1O4D A;  2ETZ A;  5EG3 B;  1QCF A;  1NZL A;  2BBU A;  2Y1M A;  3QWY A;  1HCS B;  1SHB A;  1O4A A;  3IN8 A;  1RQQ C;  2H46 E;  1IS0 A;  4JGH A;  3S8L A;  3PSK A;  1OPL A;  4OHD A;  1CJ1 A;  2L6K A;  3UF4 A;  2GSB A;  5DF6 A;  1M27 A;  3T04 A;  2HMH A;  4JEG A;  1BFJ A;  3VS6 A;  3TL0 A;  2Y3A B;  3K2T A;  1A1C A;  1BG1 A;  2SRC A;  2K79 B;  2FCI A;  3OB1 B;  1QAD A;  1FYR A;  1O4P A;  5HKW A;  3EAZ A;  3HHM B;  2C9W A;  2ROR A;  1O46 A;  3S9K A;  1BKL A;  1SKJ A;  4XZ1 A;  4K44 A;  1LCJ A;  1O4I A;  2LNX A;  4H34 A;  1O4K A;  4F5A A;  1A08 A;  1FU5 A;  2HCK A;  5IBM A;  1Z3K A;  2EYZ A;  1F2F A;  4E93 A;  1A81 A;  1FU6 A;  2ABL A;  5HKZ A;  1KA6 A;  1BLJ A;  4OHE A;  2EL8 A;  3VRN A;  4LUE A;  3PLF B;  1B47 A;  3VS1 A;  1UUS A;  2XP1 A;  1AB2 A;  3GXW A;  4A4B A;  3NHN A;  1F1W A;  1BMB A;  3GQI B;  3BUN B;  3IMJ A;  3VS4 A;  2B3O A;  1O4B A;  4OHH A;  1O41 A;  1FMK A;  1SHA A;  1A07 A;  2C0T A;  3OVE A;  1O4Q A;  1YVL A;  2CBL A;  3C7I A;  4EY0 A;  2LCT A;  1RPY A;  2QMS A;  4FBN A;  4DGX A;  3OV1 A;  1BHF A;  3BUX B;  1AYD A;  1O4N A;  4P9Z A;  1TZE E;  3WA4 A;  2H5K A;  1R1P A;  1LUK A;  1O47 A;  2LNW A;  1FBZ A;  1BFI A;  4U17 A;  3UYO A;  1JYR A;  1MIL A;  1H9O A;  2IZV A;  2RMX A;  1O4L A;  1BLK A;  3VRQ A;  2KGY A;  5EEL A;  1OO3 A;  3K2M A;  3M7F A;  4JE4 A;  1A09 A;  2IUH A;  2PNA A;  3VS7 A;  1CSY A;  1KA7 A;  2CI8 A;  3PFV A;  2YU7 A;  2DLZ A;  1A1E A;  1RJA A;  4D8K A;  1AOU F;  1M61 A;  5AXI A;  1JWO A;  2Y1N A;  2MRJ A;  2OZO A;  2EO3 A;  1CWD L;  3N7Y A;  1TCE A;  4ROJ A;  2MRK A;  4U1P A;  3S8O A;  3BUO B;  5D0J A;  2EYY A;  1CSZ A;  1JYQ A;  3VRZ A;  4OHL A;  2LQN A;  1BHH B;  2KNO A;  1P13 A;  1LCK A;  4XZ0 A;  1O48 A;  2L3T A;  5EEQ A;  2H8H A;  4X6S A;  3IMD A;  4F5B A;  4TZI A;  2KK6 A;  2VIF A;  5AUL A;  1NRV A;  4F59 A;  1JYU A;  1KSW A;  1O44 A;  1UUR A;  2MC1 A;  2PLD A;  5CDW A;  4P9V A;  2PTK A;  1KC2 A;  3S8N A;  2IUI A;  1AOT F;  2PLE A;  1FHS A;  4FL2 A;  1IJR A;  2RVF A;  1LUM A;  2L4K A;  2DLY A;  4K2R A; 
#chains in the Genus database with same CATH homology
 3HIZ B;  3PSJ A;  4GPL B;  2DCR A;  2EU0 A;  2FO0 A;  2JYQ A;  3CD3 A;  3ZNI A;  5DC9 A;  3VGO A;  1CWE A;  2HDX A;  1LUI A;  4A4C A;  1O49 A;  3VRY A;  5DC4 A;  1D1Z A;  3OB2 B;  2C0I A;  3VRP A;  3MXC A;  1WQU A;  1BHH A;  5KAZ A;  2IUG A;  1OO4 A;  4GWF A;  4K45 A;  4LUD A;  5DC0 B;  3VS0 A;  1AD5 A;  3VS3 A;  5BO4 A;  1D4W A;  4NWF A;  4WWQ A;  2EO6 A;  1O4C A;  2AUG A;  3VS5 A;  1AYA A;  1JU5 A;  2LQW A;  1R1Q A;  3TKZ A;  2PNB A;  3GXX A;  2HUW A;  1O4H A;  4H1O A;  1HCT B;  3PQZ A;  1SPR A;  2EKX A;  1GHU A;  1AYC A;  2CRH A;  1X0N A;  1I3Z A;  1AYB A;  3KFJ A;  2RSY A;  3CXL A;  2HDV A;  1QG1 E;  1O4M A;  4DGP A;  1O42 A;  2DM0 A;  3N84 A;  2CR4 A;  2CIA A;  3EAC A;  2AOB A;  1SPS A;  5GJH A;  3MAZ A;  1BM2 A;  4K11 A;  2SHP A;  1K9A A;  1A1A A;  1LKK A;  1X6C A;  4EIH A;  3BUM B;  5GJI A;  1Y1U A;  1YVH A;  3VS2 A;  2EOB A;  1FBV A;  2CI9 A;  4NWG A;  4FL3 A;  1X27 A;  1Y57 A;  2GE9 A;  3PS5 A;  5EHR A;  1PIC A;  1XA6 A;  4L1B B;  1GRI A;  1O4J A;  1G83 A;  3BKB A;  4QSY A;  1MW4 A;  1O4E A;  3N8M A;  3OP0 A;  1LKL A;  2DX0 A;  5IBS A;  1O4R A;  2C0O A;  3US4 A;  3VRR A;  3QWX X;  1O45 A;  2DVJ A;  2CS0 A;  3VRO A;  1OPK A;  1A1B A;  4E68 A;  1ZFP E;  1R1S A;  1O4F A;  2MQI A;  3IN7 A;  1BKM A;  1SHD A;  2EYV A;  2YSX A;  1O4G A;  5J3X A;  5I6V A;  2MK2 A;  2K7A B;  2ECD A;  1BF5 A;  3BUW B;  1NZV A;  2OQ1 A;  3CBL A;  3CWG A;  4OHI A;  3MXY A;  1LUN A;  1D4T A;  4GL9 E;  2AOA A;  3HCK A;  4M4Z A;  3PJP A;  5EHP A;  5HKY A;  1O4O A;  1O43 A;  1O4D A;  2ETZ A;  5EG3 B;  1QCF A;  1NZL A;  2BBU A;  2Y1M A;  3QWY A;  1HCS B;  1SHB A;  1O4A A;  3IN8 A;  1RQQ C;  2H46 E;  1IS0 A;  4JGH A;  3S8L A;  3PSK A;  1OPL A;  4OHD A;  1CJ1 A;  2L6K A;  3UF4 A;  2GSB A;  5DF6 A;  1M27 A;  3T04 A;  2HMH A;  4JEG A;  1BFJ A;  3VS6 A;  3TL0 A;  2Y3A B;  1A1C A;  1BG1 A;  2SRC A;  2K79 B;  2FCI A;  3OB1 B;  1QAD A;  1FYR A;  1O4P A;  5HKW A;  3EAZ A;  3HHM B;  2C9W A;  2ROR A;  1O46 A;  3S9K A;  1BKL A;  1SKJ A;  4XZ1 A;  4K44 A;  1LCJ A;  1O4I A;  2LNX A;  4H34 A;  1O4K A;  4F5A A;  1A08 A;  1FU5 A;  2HCK A;  5IBM A;  1Z3K A;  2EYZ A;  1F2F A;  4E93 A;  1A81 A;  1FU6 A;  2ABL A;  5HKZ A;  1KA6 A;  1BLJ A;  4OHE A;  2EL8 A;  3VRN A;  4LUE A;  3PLF B;  1B47 A;  3VS1 A;  1UUS A;  2XP1 A;  1AB2 A;  3GXW A;  4A4B A;  3NHN A;  1F1W A;  1BMB A;  3GQI B;  3BUN B;  3IMJ A;  3VS4 A;  2B3O A;  1O4B A;  4OHH A;  1O41 A;  1FMK A;  1SHA A;  1A07 A;  2C0T A;  3OVE A;  1O4Q A;  1YVL A;  2CBL A;  3C7I A;  4EY0 A;  2LCT A;  1RPY A;  2QMS A;  4FBN A;  4DGX A;  3OV1 A;  1BHF A;  3BUX B;  1AYD A;  1O4N A;  4P9Z A;  1TZE E;  3WA4 A;  2H5K A;  1R1P A;  1LUK A;  1O47 A;  2LNW A;  1FBZ A;  1BFI A;  4U17 A;  3UYO A;  1JYR A;  1MIL A;  1H9O A;  2IZV A;  2RMX A;  1O4L A;  1BLK A;  3VRQ A;  5EEL A;  1OO3 A;  3K2M A;  3M7F A;  4JE4 A;  1A09 A;  2IUH A;  2PNA A;  3VS7 A;  1CSY A;  1KA7 A;  2CI8 A;  3PFV A;  2YU7 A;  2DLZ A;  1A1E A;  1RJA A;  4D8K A;  1AOU F;  1M61 A;  5AXI A;  1JWO A;  2Y1N A;  2MRJ A;  2OZO A;  2EO3 A;  1CWD L;  3N7Y A;  1TCE A;  4ROJ A;  2MRK A;  4U1P A;  3S8O A;  3BUO B;  5D0J A;  2EYY A;  1CSZ A;  1JYQ A;  3VRZ A;  4OHL A;  2LQN A;  1BHH B;  2KNO A;  1P13 A;  1LCK A;  4XZ0 A;  1O48 A;  2L3T A;  5EEQ A;  2H8H A;  4X6S A;  3IMD A;  4F5B A;  4TZI A;  2KK6 A;  2VIF A;  5AUL A;  1NRV A;  4F59 A;  1JYU A;  1KSW A;  1O44 A;  1UUR A;  2MC1 A;  2PLD A;  5CDW A;  4P9V A;  2PTK A;  1KC2 A;  3S8N A;  2IUI A;  1AOT F;  2PLE A;  1FHS A;  4FL2 A;  1IJR A;  2RVF A;  1LUM A;  2L4K A;  2DLY A;  4K2R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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