1O4IA

Crystal structure of sh2 in complex with pas219.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4iA00
1RJAA 1AOTF 1FU5A 3US4A 1BF5A 1IS0A 4XZ0A 1KA6A 1JWOA 4WWQA 3CXLA 4OHEA 3VRZA 4LUEA 3PQZA 1GRIA 2EU0A 2VIFA 4F5AA 2KK6A 1O43A 4OHDA 1A1AA 2QMSA 4GL9E 2IUHA 4EIHA 1O45A 1BLKA 5AXIA 2MC1A 2Y1NA 3UF4A 1BHHA 5GJIA 2HDXA 2GE9A 2H8HA 4L1BB 3UYOA 4XZ1A 3GQIB 1HCSB 2DX0A 1F1WA 2ABLA 1SHBA 1BFIA 1O4JA 4U1PA 1O44A 3PSKA 1Y1UA 2YU7A 3VS7A 1KA7A 1O4HA 1QADA 1F2FA 2HCKA 1XA6A 1M27A 1H9OA 2PTKA 1YVHA 2DM0A 1HCTB 2GSBA 1R1PA 5DC0B 1QG1E 1IJRA 1OO3A 5EHPA 1A1BA 1SHDA 1QCFA 1O41A 1FBVA 1JYQA 1O4RA 3VRPA 4D8KA 5EEQA 1CSYA 1O4KA 1O4EA 1CWDL 2IUGA 2OZOA 3QWXX 1AB2A 1SPRA 1O4BA 2CI9A 3WA4A 3HCKA 1OPKA 5DC4A 1SKJA 3IN7A 1RQQC 3IMDA 1UURA 4H1OA 3VS1A 3CWGA 2L6KA 3OP0A 2Y3AB 2C9WA 4P9VA 4FL2A 1O4CA 5IBMA 2CIAA 2YSXA 3OV1A 3OVEA 2EL8A 4EY0A 3MXCA 2CI8A 1A09A 2SRCA 5D0JA 2BBUA 1BG1A 3BKBA 4K2RA 4P9ZA 1Y57A 3VRQA 1O4OA 2MRJA 1AD5A 3NHNA 3VGOA 3HHMB 1PICA 1KC2A 4A4BA 2K79B 3EAZA 1WQUA 1O47A 4TZIA 2RVFA 5J3XA 2AUGA 2DVJA 2EYVA 5BO4A 1LKKA 5CDWA 1AYCA 3PS5A 3VROA 3S8OA 1AYBA 2AOBA 3S8NA 4FL3A 4OHHA 1OO4A 4U17A 3VS4A 2IUIA 1TZEE 1OPLA 1I3ZA 3IMJA 1O4DA 3MAZA 1M61A 4GWFA 4F5BA 2ECDA 1Z3KA 1CWEA 1BHHB 1TCEA 2EYZA 3M7FA 1D4WA 1LCKA 1O4QA 1O4LA 3TKZA 2IZVA 1NZVA 2RMXA 1K9AA 1O4GA 2XP1A 3VRYA 2B3OA 2PNBA 3PSJA 1AYAA 1O46A 3QWYA 1X27A 4NWFA 1LKLA 4GPLB 5IBSA 3GXXA 1JU5A 3BUWB 1GHUA 2MK2A 1FU6A 1BMBA 1BLJA 1O4MA 5AULA 3CD3A 2H5KA 2C0OA 1AYDA 1G83A 2DLZA 5GJHA 2SHPA 2HDVA 2C0TA 1O49A 1R1SA 3BUMB 3ZNIA 1RPYA 2C0IA 4E93A 1MW4A 1B47A 5KAZA 3VS5A 1NRVA 3OB1B 1A81A 4H34A 1O4NA 2JYQA 2EYYA 5HKZA 2MRKA 4NWGA 4FBNA 1LCJA 3CBLA 1A1CA 1JYUA 5EELA 2L3TA 2EOBA 3PLFB 1FYRA 3S8LA 3BUXB 4DGPA 1A07A 4A4CA 4QSYA 2EO6A 1FBZA 3GXWA 1SPSA 2PNAA 1UUSA 1O4FA 5I6VA 1O4AA 3N7YA 3VS6A 3MXYA 1ZFPE 2RORA 1D4TA 2CRHA 4ROJA 5DC9A 1BKMA 2LQWA 4JGHA 5HKWA 2DLYA 2H46E 4LUDA 3TL0A 2EKXA 4OHIA 4JE4A 5DF6A 1X0NA 1NZLA 4K11A 4DGXA 2EO3A 2CS0A 1D1ZA 3T04A 1LUNA 3S9KA 3EACA 3VRRA 2CBLA 3PJPA 2LQNA 4M4ZA 1FMKA 3OB2B 2RSYA 1O4IA 2OQ1A 2KNOA 4X6SA 3C7IA 4E68A 1KSWA 3VS0A 1MILA 1O4PA 1BM2A 5EHRA 4K44A 2MQIA 1YVLA 2PLDA 2HMHA 2DCRA 1LUMA 1O42A 3K2MA 4JEGA 4OHLA 3IN8A 1CJ1A 1A08A 4K45A 1BHFA 1FHSA 2LCTA 2FO0A 2HUWA 2L4KA 3VS2A 2FCIA 3KFJA 1P13A 3PFVA 3VS3A 2K7AB 5HKYA 3VRNA 1A1EA 5EG3B 1AOUF 2LNXA 3N84A 1BKLA 3BUNB 1O48A 3HIZB 2AOAA 1LUIA 4F59A 2PLEA 1LUKA 2Y1MA 2CR4A 3BUOB 1JYRA 1R1QA 1BFJA 1SHAA 1X6CA 2ETZA 2LNWA 3N8MA 1CSZA
chains in the Genus database with same CATH superfamily
1RJAA 1AOTF 1FU5A 3US4A 1BF5A 1IS0A 4XZ0A 1KA6A 1JWOA 4WWQA 3CXLA 4OHEA 3VRZA 4LUEA 3PQZA 1GRIA 2EU0A 2VIFA 4F5AA 2KK6A 1O43A 4OHDA 1A1AA 2QMSA 2KGYA 3K2TA 4GL9E 2IUHA 4EIHA 1O45A 1BLKA 5AXIA 2MC1A 2Y1NA 3UF4A 1BHHA 5GJIA 2HDXA 2GE9A 2H8HA 4L1BB 3UYOA 4XZ1A 3GQIB 1HCSB 2DX0A 1F1WA 2ABLA 1SHBA 1BFIA 1O4JA 4U1PA 1O44A 3PSKA 1Y1UA 2YU7A 3VS7A 1KA7A 1O4HA 1QADA 1F2FA 2HCKA 1XA6A 1M27A 1H9OA 2PTKA 1YVHA 2DM0A 1HCTB 2GSBA 1R1PA 5DC0B 1QG1E 1IJRA 1OO3A 5EHPA 1A1BA 1SHDA 1QCFA 1O41A 1FBVA 1JYQA 1O4RA 3VRPA 4D8KA 5EEQA 1CSYA 1O4KA 1O4EA 1CWDL 2IUGA 2OZOA 3QWXX 1AB2A 1SPRA 1O4BA 2CI9A 3WA4A 3HCKA 1OPKA 5DC4A 1SKJA 3IN7A 1RQQC 3IMDA 1UURA 4H1OA 3VS1A 3CWGA 2L6KA 3OP0A 2Y3AB 2C9WA 4P9VA 4FL2A 1O4CA 5IBMA 2CIAA 2YSXA 3OV1A 3OVEA 2EL8A 4EY0A 3MXCA 2CI8A 1A09A 2SRCA 5D0JA 2BBUA 1BG1A 3BKBA 4K2RA 4P9ZA 1Y57A 3VRQA 1O4OA 2MRJA 1AD5A 3NHNA 3VGOA 3HHMB 1PICA 1KC2A 4A4BA 2K79B 3EAZA 1WQUA 1O47A 4TZIA 2RVFA 5J3XA 2AUGA 2DVJA 2EYVA 5BO4A 1LKKA 5CDWA 1AYCA 3PS5A 3VROA 3S8OA 1AYBA 2AOBA 3S8NA 4FL3A 4OHHA 1OO4A 4U17A 3VS4A 2IUIA 1TZEE 2LRAA 1OPLA 1I3ZA 3IMJA 1O4DA 3MAZA 1M61A 4GWFA 4F5BA 2ECDA 1Z3KA 1CWEA 1BHHB 1TCEA 2EYZA 3M7FA 1D4WA 1LCKA 1O4QA 1O4LA 3TKZA 2IZVA 1NZVA 2RMXA 1K9AA 1O4GA 2XP1A 3VRYA 2B3OA 2PNBA 3PSJA 1AYAA 1O46A 3QWYA 1X27A 4NWFA 1LKLA 4GPLB 5IBSA 3GXXA 1JU5A 3BUWB 1GHUA 2MK2A 1FU6A 1BMBA 1BLJA 1O4MA 5AULA 3CD3A 2H5KA 2C0OA 1AYDA 1G83A 2DLZA 5GJHA 2SHPA 2HDVA 2C0TA 1O49A 1R1SA 3BUMB 3ZNIA 1RPYA 2C0IA 4E93A 1MW4A 1B47A 5KAZA 3VS5A 1NRVA 3OB1B 1A81A 4H34A 1O4NA 2JYQA 2EYYA 5HKZA 2MRKA 4NWGA 4FBNA 1LCJA 3CBLA 1A1CA 1JYUA 5EELA 2L3TA 2EOBA 3PLFB 1FYRA 3S8LA 3BUXB 4DGPA 1A07A 4A4CA 4QSYA 2EO6A 1FBZA 3GXWA 1SPSA 2PNAA 1UUSA 1O4FA 5I6VA 1O4AA 3N7YA 3VS6A 3MXYA 1ZFPE 2RORA 1D4TA 2CRHA 4ROJA 5DC9A 1BKMA 2LQWA 4JGHA 5HKWA 2DLYA 2H46E 4LUDA 3TL0A 2EKXA 4OHIA 4JE4A 5DF6A 1X0NA 1NZLA 4K11A 4DGXA 2EO3A 2CS0A 1D1ZA 3T04A 1LUNA 3S9KA 3EACA 3VRRA 2CBLA 3PJPA 2LQNA 4M4ZA 1FMKA 3OB2B 2RSYA 1O4IA 3LYVA 2OQ1A 2KNOA 4X6SA 3C7IA 4E68A 1KSWA 3VS0A 1MILA 1O4PA 1BM2A 5EHRA 4K44A 2MQIA 1YVLA 2PLDA 2HMHA 2DCRA 1LUMA 1O42A 3K2MA 4JEGA 4OHLA 3IN8A 1CJ1A 1A08A 4K45A 1BHFA 1FHSA 2LCTA 2FO0A 2HUWA 2L4KA 3VS2A 2FCIA 3KFJA 1P13A 3PFVA 3VS3A 2K7AB 5HKYA 3VRNA 1A1EA 5EG3B 1AOUF 2LNXA 3N84A 1BKLA 3BUNB 1O48A 3HIZB 2AOAA 1LUIA 4F59A 2PLEA 1LUKA 2Y1MA 2CR4A 3BUOB 1JYRA 1R1QA 1BFJA 1SHAA 1X6CA 2ETZA 2LNWA 3N8MA 1CSZA
chains in the Genus database with same CATH topology
1RJAA 1AOTF 1FU5A 3US4A 1BF5A 1IS0A 4XZ0A 1KA6A 1JWOA 4WWQA 3CXLA 4OHEA 3VRZA 4LUEA 3PQZA 1GRIA 2EU0A 2VIFA 4F5AA 2KK6A 1O43A 4OHDA 1A1AA 2QMSA 4GL9E 2IUHA 4EIHA 1O45A 1BLKA 5AXIA 2MC1A 2Y1NA 3UF4A 1BHHA 5GJIA 2HDXA 2GE9A 2H8HA 4L1BB 3UYOA 4XZ1A 3GQIB 1HCSB 2DX0A 1F1WA 2ABLA 1SHBA 1BFIA 1O4JA 4U1PA 1O44A 3PSKA 1Y1UA 2YU7A 3VS7A 1KA7A 1O4HA 1QADA 1F2FA 2HCKA 1XA6A 1M27A 1H9OA 2PTKA 1YVHA 2DM0A 1HCTB 2GSBA 1R1PA 5DC0B 1QG1E 1IJRA 1OO3A 5EHPA 1A1BA 1SHDA 1QCFA 1O41A 1FBVA 1JYQA 1O4RA 3VRPA 4D8KA 5EEQA 1CSYA 1O4KA 1O4EA 1CWDL 2IUGA 2OZOA 3QWXX 1AB2A 1SPRA 1O4BA 2CI9A 3WA4A 3HCKA 1OPKA 5DC4A 1SKJA 3IN7A 1RQQC 3IMDA 1UURA 4H1OA 3VS1A 3CWGA 2L6KA 3OP0A 2Y3AB 2C9WA 4P9VA 4FL2A 1O4CA 5IBMA 2CIAA 2YSXA 3OV1A 3OVEA 2EL8A 4EY0A 3MXCA 2CI8A 1A09A 2SRCA 5D0JA 2BBUA 1BG1A 3BKBA 4K2RA 4P9ZA 1Y57A 3VRQA 1O4OA 2MRJA 1AD5A 3NHNA 3VGOA 3HHMB 1PICA 1KC2A 4A4BA 2K79B 3EAZA 1WQUA 1O47A 4TZIA 2RVFA 5J3XA 2AUGA 2DVJA 2EYVA 5BO4A 1LKKA 5CDWA 1AYCA 3PS5A 3VROA 3S8OA 1AYBA 2AOBA 3S8NA 4FL3A 4OHHA 1OO4A 4U17A 3VS4A 2IUIA 1TZEE 1OPLA 1I3ZA 3IMJA 1O4DA 3MAZA 1M61A 4GWFA 4F5BA 2ECDA 1Z3KA 1CWEA 1BHHB 1TCEA 2EYZA 3M7FA 1D4WA 1LCKA 1O4QA 1O4LA 3TKZA 2IZVA 1NZVA 2RMXA 1K9AA 1O4GA 2XP1A 3VRYA 2B3OA 2PNBA 3PSJA 1AYAA 1O46A 3QWYA 1X27A 4NWFA 1LKLA 4GPLB 5IBSA 3GXXA 1JU5A 3BUWB 1GHUA 2MK2A 1FU6A 1BMBA 1BLJA 1O4MA 5AULA 3CD3A 2H5KA 2C0OA 1AYDA 1G83A 2DLZA 5GJHA 2SHPA 2HDVA 2C0TA 1O49A 1R1SA 3BUMB 3ZNIA 1RPYA 2C0IA 4E93A 1MW4A 1B47A 5KAZA 3VS5A 1NRVA 3OB1B 1A81A 4H34A 1O4NA 2JYQA 2EYYA 5HKZA 2MRKA 4NWGA 4FBNA 1LCJA 3CBLA 1A1CA 1JYUA 5EELA 2L3TA 2EOBA 3PLFB 1FYRA 3S8LA 3BUXB 4DGPA 1A07A 4A4CA 4QSYA 2EO6A 1FBZA 3GXWA 1SPSA 2PNAA 1UUSA 1O4FA 5I6VA 1O4AA 3N7YA 3VS6A 3MXYA 1ZFPE 2RORA 1D4TA 2CRHA 4ROJA 5DC9A 1BKMA 2LQWA 4JGHA 5HKWA 2DLYA 2H46E 4LUDA 3TL0A 2EKXA 4OHIA 4JE4A 5DF6A 1X0NA 1NZLA 4K11A 4DGXA 2EO3A 2CS0A 1D1ZA 3T04A 1LUNA 3S9KA 3EACA 3VRRA 2CBLA 3PJPA 2LQNA 4M4ZA 1FMKA 3OB2B 2RSYA 1O4IA 2OQ1A 2KNOA 4X6SA 3C7IA 4E68A 1KSWA 3VS0A 1MILA 1O4PA 1BM2A 5EHRA 4K44A 2MQIA 1YVLA 2PLDA 2HMHA 2DCRA 1LUMA 1O42A 3K2MA 4JEGA 4OHLA 3IN8A 1CJ1A 1A08A 4K45A 1BHFA 1FHSA 2LCTA 2FO0A 2HUWA 2L4KA 3VS2A 2FCIA 3KFJA 1P13A 3PFVA 3VS3A 2K7AB 5HKYA 3VRNA 1A1EA 5EG3B 1AOUF 2LNXA 3N84A 1BKLA 3BUNB 1O48A 3HIZB 2AOAA 1LUIA 4F59A 2PLEA 1LUKA 2Y1MA 2CR4A 3BUOB 1JYRA 1R1QA 1BFJA 1SHAA 1X6CA 2ETZA 2LNWA 3N8MA 1CSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RJA A;  1AOT F;  1FU5 A;  3US4 A;  1BF5 A;  1IS0 A;  4XZ0 A;  1KA6 A;  1JWO A;  4WWQ A;  3CXL A;  4OHE A;  3VRZ A;  4LUE A;  3PQZ A;  1GRI A;  2EU0 A;  2VIF A;  4F5A A;  2KK6 A;  1O43 A;  4OHD A;  1A1A A;  2QMS A;  4GL9 E;  2IUH A;  4EIH A;  1O45 A;  1BLK A;  5AXI A;  2MC1 A;  2Y1N A;  3UF4 A;  1BHH A;  5GJI A;  2HDX A;  2GE9 A;  2H8H A;  4L1B B;  3UYO A;  4XZ1 A;  3GQI B;  1HCS B;  2DX0 A;  1F1W A;  2ABL A;  1SHB A;  1BFI A;  1O4J A;  4U1P A;  1O44 A;  3PSK A;  1Y1U A;  2YU7 A;  3VS7 A;  1KA7 A;  1O4H A;  1QAD A;  1F2F A;  2HCK A;  1XA6 A;  1M27 A;  1H9O A;  2PTK A;  1YVH A;  2DM0 A;  1HCT B;  2GSB A;  1R1P A;  5DC0 B;  1QG1 E;  1IJR A;  1OO3 A;  5EHP A;  1A1B A;  1SHD A;  1QCF A;  1O41 A;  1FBV A;  1JYQ A;  1O4R A;  3VRP A;  4D8K A;  5EEQ A;  1CSY A;  1O4K A;  1O4E A;  1CWD L;  2IUG A;  2OZO A;  3QWX X;  1AB2 A;  1SPR A;  1O4B A;  2CI9 A;  3WA4 A;  3HCK A;  1OPK A;  5DC4 A;  1SKJ A;  3IN7 A;  1RQQ C;  3IMD A;  1UUR A;  4H1O A;  3VS1 A;  3CWG A;  2L6K A;  3OP0 A;  2Y3A B;  2C9W A;  4P9V A;  4FL2 A;  1O4C A;  5IBM A;  2CIA A;  2YSX A;  3OV1 A;  3OVE A;  2EL8 A;  4EY0 A;  3MXC A;  2CI8 A;  1A09 A;  2SRC A;  5D0J A;  2BBU A;  1BG1 A;  3BKB A;  4K2R A;  4P9Z A;  1Y57 A;  3VRQ A;  1O4O A;  2MRJ A;  1AD5 A;  3NHN A;  3VGO A;  3HHM B;  1PIC A;  1KC2 A;  4A4B A;  2K79 B;  3EAZ A;  1WQU A;  1O47 A;  4TZI A;  2RVF A;  5J3X A;  2AUG A;  2DVJ A;  2EYV A;  5BO4 A;  1LKK A;  5CDW A;  1AYC A;  3PS5 A;  3VRO A;  3S8O A;  1AYB A;  2AOB A;  3S8N A;  4FL3 A;  4OHH A;  1OO4 A;  4U17 A;  3VS4 A;  2IUI A;  1TZE E;  1OPL A;  1I3Z A;  3IMJ A;  1O4D A;  3MAZ A;  1M61 A;  4GWF A;  4F5B A;  2ECD A;  1Z3K A;  1CWE A;  1BHH B;  1TCE A;  2EYZ A;  3M7F A;  1D4W A;  1LCK A;  1O4Q A;  1O4L A;  3TKZ A;  2IZV A;  1NZV A;  2RMX A;  1K9A A;  1O4G A;  2XP1 A;  3VRY A;  2B3O A;  2PNB A;  3PSJ A;  1AYA A;  1O46 A;  3QWY A;  1X27 A;  4NWF A;  1LKL A;  4GPL B;  5IBS A;  3GXX A;  1JU5 A;  3BUW B;  1GHU A;  2MK2 A;  1FU6 A;  1BMB A;  1BLJ A;  1O4M A;  5AUL A;  3CD3 A;  2H5K A;  2C0O A;  1AYD A;  1G83 A;  2DLZ A;  5GJH A;  2SHP A;  2HDV A;  2C0T A;  1O49 A;  1R1S A;  3BUM B;  3ZNI A;  1RPY A;  2C0I A;  4E93 A;  1MW4 A;  1B47 A;  5KAZ A;  3VS5 A;  1NRV A;  3OB1 B;  1A81 A;  4H34 A;  1O4N A;  2JYQ A;  2EYY A;  5HKZ A;  2MRK A;  4NWG A;  4FBN A;  1LCJ A;  3CBL A;  1A1C A;  1JYU A;  5EEL A;  2L3T A;  2EOB A;  3PLF B;  1FYR A;  3S8L A;  3BUX B;  4DGP A;  1A07 A;  4A4C A;  4QSY A;  2EO6 A;  1FBZ A;  3GXW A;  1SPS A;  2PNA A;  1UUS A;  1O4F A;  5I6V A;  1O4A A;  3N7Y A;  3VS6 A;  3MXY A;  1ZFP E;  2ROR A;  1D4T A;  2CRH A;  4ROJ A;  5DC9 A;  1BKM A;  2LQW A;  4JGH A;  5HKW A;  2DLY A;  2H46 E;  4LUD A;  3TL0 A;  2EKX A;  4OHI A;  4JE4 A;  5DF6 A;  1X0N A;  1NZL A;  4K11 A;  4DGX A;  2EO3 A;  2CS0 A;  1D1Z A;  3T04 A;  1LUN A;  3S9K A;  3EAC A;  3VRR A;  2CBL A;  3PJP A;  2LQN A;  4M4Z A;  1FMK A;  3OB2 B;  2RSY A;  1O4I A;  2OQ1 A;  2KNO A;  4X6S A;  3C7I A;  4E68 A;  1KSW A;  3VS0 A;  1MIL A;  1O4P A;  1BM2 A;  5EHR A;  4K44 A;  2MQI A;  1YVL A;  2PLD A;  2HMH A;  2DCR A;  1LUM A;  1O42 A;  3K2M A;  4JEG A;  4OHL A;  3IN8 A;  1CJ1 A;  1A08 A;  4K45 A;  1BHF A;  1FHS A;  2LCT A;  2FO0 A;  2HUW A;  2L4K A;  3VS2 A;  2FCI A;  3KFJ A;  1P13 A;  3PFV A;  3VS3 A;  2K7A B;  5HKY A;  3VRN A;  1A1E A;  5EG3 B;  1AOU F;  2LNX A;  3N84 A;  1BKL A;  3BUN B;  1O48 A;  3HIZ B;  2AOA A;  1LUI A;  4F59 A;  2PLE A;  1LUK A;  2Y1M A;  2CR4 A;  3BUO B;  1JYR A;  1R1Q A;  1BFJ A;  1SHA A;  1X6C A;  2ETZ A;  2LNW A;  3N8M A;  1CSZ A; 
#chains in the Genus database with same CATH topology
 1RJA A;  1AOT F;  1FU5 A;  3US4 A;  1BF5 A;  1IS0 A;  4XZ0 A;  1KA6 A;  1JWO A;  4WWQ A;  3CXL A;  4OHE A;  3VRZ A;  4LUE A;  3PQZ A;  1GRI A;  2EU0 A;  2VIF A;  4F5A A;  2KK6 A;  1O43 A;  4OHD A;  1A1A A;  2QMS A;  2KGY A;  3K2T A;  4GL9 E;  2IUH A;  4EIH A;  1O45 A;  1BLK A;  5AXI A;  2MC1 A;  2Y1N A;  3UF4 A;  1BHH A;  5GJI A;  2HDX A;  2GE9 A;  2H8H A;  4L1B B;  3UYO A;  4XZ1 A;  3GQI B;  1HCS B;  2DX0 A;  1F1W A;  2ABL A;  1SHB A;  1BFI A;  1O4J A;  4U1P A;  1O44 A;  3PSK A;  1Y1U A;  2YU7 A;  3VS7 A;  1KA7 A;  1O4H A;  1QAD A;  1F2F A;  2HCK A;  1XA6 A;  1M27 A;  1H9O A;  2PTK A;  1YVH A;  2DM0 A;  1HCT B;  2GSB A;  1R1P A;  5DC0 B;  1QG1 E;  1IJR A;  1OO3 A;  5EHP A;  1A1B A;  1SHD A;  1QCF A;  1O41 A;  1FBV A;  1JYQ A;  1O4R A;  3VRP A;  4D8K A;  5EEQ A;  1CSY A;  1O4K A;  1O4E A;  1CWD L;  2IUG A;  2OZO A;  3QWX X;  1AB2 A;  1SPR A;  1O4B A;  2CI9 A;  3WA4 A;  3HCK A;  1OPK A;  5DC4 A;  1SKJ A;  3IN7 A;  1RQQ C;  3IMD A;  1UUR A;  4H1O A;  3VS1 A;  3CWG A;  2L6K A;  3OP0 A;  2Y3A B;  2C9W A;  4P9V A;  4FL2 A;  1O4C A;  5IBM A;  2CIA A;  2YSX A;  3OV1 A;  3OVE A;  2EL8 A;  4EY0 A;  3MXC A;  2CI8 A;  1A09 A;  2SRC A;  5D0J A;  2BBU A;  1BG1 A;  3BKB A;  4K2R A;  4P9Z A;  1Y57 A;  3VRQ A;  1O4O A;  2MRJ A;  1AD5 A;  3NHN A;  3VGO A;  3HHM B;  1PIC A;  1KC2 A;  4A4B A;  2K79 B;  3EAZ A;  1WQU A;  1O47 A;  4TZI A;  2RVF A;  5J3X A;  2AUG A;  2DVJ A;  2EYV A;  5BO4 A;  1LKK A;  5CDW A;  1AYC A;  3PS5 A;  3VRO A;  3S8O A;  1AYB A;  2AOB A;  3S8N A;  4FL3 A;  4OHH A;  1OO4 A;  4U17 A;  3VS4 A;  2IUI A;  1TZE E;  2LRA A;  1OPL A;  1I3Z A;  3IMJ A;  1O4D A;  3MAZ A;  1M61 A;  4GWF A;  4F5B A;  2ECD A;  1Z3K A;  1CWE A;  1BHH B;  1TCE A;  2EYZ A;  3M7F A;  1D4W A;  1LCK A;  1O4Q A;  1O4L A;  3TKZ A;  2IZV A;  1NZV A;  2RMX A;  1K9A A;  1O4G A;  2XP1 A;  3VRY A;  2B3O A;  2PNB A;  3PSJ A;  1AYA A;  1O46 A;  3QWY A;  1X27 A;  4NWF A;  1LKL A;  4GPL B;  5IBS A;  3GXX A;  1JU5 A;  3BUW B;  1GHU A;  2MK2 A;  1FU6 A;  1BMB A;  1BLJ A;  1O4M A;  5AUL A;  3CD3 A;  2H5K A;  2C0O A;  1AYD A;  1G83 A;  2DLZ A;  5GJH A;  2SHP A;  2HDV A;  2C0T A;  1O49 A;  1R1S A;  3BUM B;  3ZNI A;  1RPY A;  2C0I A;  4E93 A;  1MW4 A;  1B47 A;  5KAZ A;  3VS5 A;  1NRV A;  3OB1 B;  1A81 A;  4H34 A;  1O4N A;  2JYQ A;  2EYY A;  5HKZ A;  2MRK A;  4NWG A;  4FBN A;  1LCJ A;  3CBL A;  1A1C A;  1JYU A;  5EEL A;  2L3T A;  2EOB A;  3PLF B;  1FYR A;  3S8L A;  3BUX B;  4DGP A;  1A07 A;  4A4C A;  4QSY A;  2EO6 A;  1FBZ A;  3GXW A;  1SPS A;  2PNA A;  1UUS A;  1O4F A;  5I6V A;  1O4A A;  3N7Y A;  3VS6 A;  3MXY A;  1ZFP E;  2ROR A;  1D4T A;  2CRH A;  4ROJ A;  5DC9 A;  1BKM A;  2LQW A;  4JGH A;  5HKW A;  2DLY A;  2H46 E;  4LUD A;  3TL0 A;  2EKX A;  4OHI A;  4JE4 A;  5DF6 A;  1X0N A;  1NZL A;  4K11 A;  4DGX A;  2EO3 A;  2CS0 A;  1D1Z A;  3T04 A;  1LUN A;  3S9K A;  3EAC A;  3VRR A;  2CBL A;  3PJP A;  2LQN A;  4M4Z A;  1FMK A;  3OB2 B;  2RSY A;  1O4I A;  3LYV A;  2OQ1 A;  2KNO A;  4X6S A;  3C7I A;  4E68 A;  1KSW A;  3VS0 A;  1MIL A;  1O4P A;  1BM2 A;  5EHR A;  4K44 A;  2MQI A;  1YVL A;  2PLD A;  2HMH A;  2DCR A;  1LUM A;  1O42 A;  3K2M A;  4JEG A;  4OHL A;  3IN8 A;  1CJ1 A;  1A08 A;  4K45 A;  1BHF A;  1FHS A;  2LCT A;  2FO0 A;  2HUW A;  2L4K A;  3VS2 A;  2FCI A;  3KFJ A;  1P13 A;  3PFV A;  3VS3 A;  2K7A B;  5HKY A;  3VRN A;  1A1E A;  5EG3 B;  1AOU F;  2LNX A;  3N84 A;  1BKL A;  3BUN B;  1O48 A;  3HIZ B;  2AOA A;  1LUI A;  4F59 A;  2PLE A;  1LUK A;  2Y1M A;  2CR4 A;  3BUO B;  1JYR A;  1R1Q A;  1BFJ A;  1SHA A;  1X6C A;  2ETZ A;  2LNW A;  3N8M A;  1CSZ A; 
#chains in the Genus database with same CATH homology
 1RJA A;  1AOT F;  1FU5 A;  3US4 A;  1BF5 A;  1IS0 A;  4XZ0 A;  1KA6 A;  1JWO A;  4WWQ A;  3CXL A;  4OHE A;  3VRZ A;  4LUE A;  3PQZ A;  1GRI A;  2EU0 A;  2VIF A;  4F5A A;  2KK6 A;  1O43 A;  4OHD A;  1A1A A;  2QMS A;  4GL9 E;  2IUH A;  4EIH A;  1O45 A;  1BLK A;  5AXI A;  2MC1 A;  2Y1N A;  3UF4 A;  1BHH A;  5GJI A;  2HDX A;  2GE9 A;  2H8H A;  4L1B B;  3UYO A;  4XZ1 A;  3GQI B;  1HCS B;  2DX0 A;  1F1W A;  2ABL A;  1SHB A;  1BFI A;  1O4J A;  4U1P A;  1O44 A;  3PSK A;  1Y1U A;  2YU7 A;  3VS7 A;  1KA7 A;  1O4H A;  1QAD A;  1F2F A;  2HCK A;  1XA6 A;  1M27 A;  1H9O A;  2PTK A;  1YVH A;  2DM0 A;  1HCT B;  2GSB A;  1R1P A;  5DC0 B;  1QG1 E;  1IJR A;  1OO3 A;  5EHP A;  1A1B A;  1SHD A;  1QCF A;  1O41 A;  1FBV A;  1JYQ A;  1O4R A;  3VRP A;  4D8K A;  5EEQ A;  1CSY A;  1O4K A;  1O4E A;  1CWD L;  2IUG A;  2OZO A;  3QWX X;  1AB2 A;  1SPR A;  1O4B A;  2CI9 A;  3WA4 A;  3HCK A;  1OPK A;  5DC4 A;  1SKJ A;  3IN7 A;  1RQQ C;  3IMD A;  1UUR A;  4H1O A;  3VS1 A;  3CWG A;  2L6K A;  3OP0 A;  2Y3A B;  2C9W A;  4P9V A;  4FL2 A;  1O4C A;  5IBM A;  2CIA A;  2YSX A;  3OV1 A;  3OVE A;  2EL8 A;  4EY0 A;  3MXC A;  2CI8 A;  1A09 A;  2SRC A;  5D0J A;  2BBU A;  1BG1 A;  3BKB A;  4K2R A;  4P9Z A;  1Y57 A;  3VRQ A;  1O4O A;  2MRJ A;  1AD5 A;  3NHN A;  3VGO A;  3HHM B;  1PIC A;  1KC2 A;  4A4B A;  2K79 B;  3EAZ A;  1WQU A;  1O47 A;  4TZI A;  2RVF A;  5J3X A;  2AUG A;  2DVJ A;  2EYV A;  5BO4 A;  1LKK A;  5CDW A;  1AYC A;  3PS5 A;  3VRO A;  3S8O A;  1AYB A;  2AOB A;  3S8N A;  4FL3 A;  4OHH A;  1OO4 A;  4U17 A;  3VS4 A;  2IUI A;  1TZE E;  1OPL A;  1I3Z A;  3IMJ A;  1O4D A;  3MAZ A;  1M61 A;  4GWF A;  4F5B A;  2ECD A;  1Z3K A;  1CWE A;  1BHH B;  1TCE A;  2EYZ A;  3M7F A;  1D4W A;  1LCK A;  1O4Q A;  1O4L A;  3TKZ A;  2IZV A;  1NZV A;  2RMX A;  1K9A A;  1O4G A;  2XP1 A;  3VRY A;  2B3O A;  2PNB A;  3PSJ A;  1AYA A;  1O46 A;  3QWY A;  1X27 A;  4NWF A;  1LKL A;  4GPL B;  5IBS A;  3GXX A;  1JU5 A;  3BUW B;  1GHU A;  2MK2 A;  1FU6 A;  1BMB A;  1BLJ A;  1O4M A;  5AUL A;  3CD3 A;  2H5K A;  2C0O A;  1AYD A;  1G83 A;  2DLZ A;  5GJH A;  2SHP A;  2HDV A;  2C0T A;  1O49 A;  1R1S A;  3BUM B;  3ZNI A;  1RPY A;  2C0I A;  4E93 A;  1MW4 A;  1B47 A;  5KAZ A;  3VS5 A;  1NRV A;  3OB1 B;  1A81 A;  4H34 A;  1O4N A;  2JYQ A;  2EYY A;  5HKZ A;  2MRK A;  4NWG A;  4FBN A;  1LCJ A;  3CBL A;  1A1C A;  1JYU A;  5EEL A;  2L3T A;  2EOB A;  3PLF B;  1FYR A;  3S8L A;  3BUX B;  4DGP A;  1A07 A;  4A4C A;  4QSY A;  2EO6 A;  1FBZ A;  3GXW A;  1SPS A;  2PNA A;  1UUS A;  1O4F A;  5I6V A;  1O4A A;  3N7Y A;  3VS6 A;  3MXY A;  1ZFP E;  2ROR A;  1D4T A;  2CRH A;  4ROJ A;  5DC9 A;  1BKM A;  2LQW A;  4JGH A;  5HKW A;  2DLY A;  2H46 E;  4LUD A;  3TL0 A;  2EKX A;  4OHI A;  4JE4 A;  5DF6 A;  1X0N A;  1NZL A;  4K11 A;  4DGX A;  2EO3 A;  2CS0 A;  1D1Z A;  3T04 A;  1LUN A;  3S9K A;  3EAC A;  3VRR A;  2CBL A;  3PJP A;  2LQN A;  4M4Z A;  1FMK A;  3OB2 B;  2RSY A;  1O4I A;  2OQ1 A;  2KNO A;  4X6S A;  3C7I A;  4E68 A;  1KSW A;  3VS0 A;  1MIL A;  1O4P A;  1BM2 A;  5EHR A;  4K44 A;  2MQI A;  1YVL A;  2PLD A;  2HMH A;  2DCR A;  1LUM A;  1O42 A;  3K2M A;  4JEG A;  4OHL A;  3IN8 A;  1CJ1 A;  1A08 A;  4K45 A;  1BHF A;  1FHS A;  2LCT A;  2FO0 A;  2HUW A;  2L4K A;  3VS2 A;  2FCI A;  3KFJ A;  1P13 A;  3PFV A;  3VS3 A;  2K7A B;  5HKY A;  3VRN A;  1A1E A;  5EG3 B;  1AOU F;  2LNX A;  3N84 A;  1BKL A;  3BUN B;  1O48 A;  3HIZ B;  2AOA A;  1LUI A;  4F59 A;  2PLE A;  1LUK A;  2Y1M A;  2CR4 A;  3BUO B;  1JYR A;  1R1Q A;  1BFJ A;  1SHA A;  1X6C A;  2ETZ A;  2LNW A;  3N8M A;  1CSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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