1O4JA

Crystal structure of sh2 in complex with iso24.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4jA00
2EO3A 1BHHA 2KNOA 2EU0A 2DX0A 1A08A 2L6KA 5DF6A 5KAZA 1LKLA 3PSJA 1SHDA 1A07A 1O4BA 3BUOB 3BUMB 2CIAA 5DC9A 1AOTF 1TCEA 3GQIB 3K2MA 2YSXA 1UURA 1QCFA 4FL3A 1F2FA 1O49A 1ZFPE 3ZNIA 2EL8A 1I3ZA 3BKBA 1LUIA 4LUEA 1NZLA 4NWFA 3S8OA 1O4LA 4M4ZA 1Y57A 2JYQA 1LKKA 1SPSA 1CSYA 2IUGA 1NRVA 1JYUA 1FYRA 4E68A 2AOBA 1LCKA 1AYAA 2B3OA 3VS5A 3IN8A 1R1PA 2IUIA 3VROA 1Y1UA 3VRPA 3S9KA 2K79B 5DC0B 4QSYA 4GL9E 2PLEA 1O4AA 4XZ1A 3VRZA 5CDWA 1R1QA 1Z3KA 3CBLA 1OO3A 1AYDA 1A1EA 1O48A 3T04A 2EYYA 3PQZA 2BBUA 1O4QA 3N8MA 1FU6A 4F59A 2DLYA 1O4RA 2EKXA 5DC4A 4A4CA 2HDXA 5J3XA 4H1OA 2FO0A 1BMBA 2PNAA 1D4WA 3NHNA 4JE4A 1BG1A 1O4IA 3TKZA 3TL0A 5EHRA 3MXCA 1BFIA 1CJ1A 3VS1A 3VS3A 2RSYA 3IMJA 5GJHA 4U1PA 1P13A 2Y1NA 2C9WA 2EOBA 1JYQA 1X6CA 1CSZA 3BUWB 1LUKA 2C0TA 5IBSA 4JGHA 3C7IA 1O4HA 2EYVA 1O41A 3N84A 4K2RA 1QG1E 1HCSB 5AXIA 1SHAA 1CWEA 2MK2A 3UF4A 1O4JA 1BKMA 3PJPA 5GJIA 2CI8A 1A09A 3OV1A 2RVFA 1R1SA 1LUMA 2KK6A 2EO6A 2LQWA 4OHLA 1QADA 1SKJA 3IN7A 4EY0A 3US4A 5IBMA 4F5AA 2CRHA 1BHFA 2FCIA 2GE9A 1O4PA 1YVLA 4K45A 1X27A 1OPLA 5D0JA 3MAZA 1A1BA 1IS0A 1SPRA 2PNBA 3PFVA 3VS0A 1M27A 3VS2A 1BKLA 5EG3B 1BLKA 3PLFB 3EACA 1KSWA 4DGPA 1G83A 5I6VA 3KFJA 2IUHA 1JYRA 1AOUF 4A4BA 2LCTA 5EELA 2H8HA 3BUXB 1AYCA 5AULA 3OVEA 2CI9A 1AYBA 2HUWA 5EEQA 3UYOA 1AB2A 4H34A 1SHBA 5HKWA 1XA6A 1NZVA 1H9OA 4EIHA 4OHHA 2HCKA 2L4KA 1GHUA 2LNXA 5EHPA 2DM0A 1O4KA 1HCTB 1PICA 1F1WA 2Y1MA 4U17A 4OHDA 4OHIA 1FU5A 4FL2A 1LCJA 3S8NA 2C0IA 1YVHA 4F5BA 4ROJA 4GWFA 1A1AA 2XP1A 2H46E 3GXWA 4P9VA 2SRCA 3S8LA 1MILA 1UUSA 1OO4A 1O43A 1D1ZA 2C0OA 1MW4A 1BF5A 1D4TA 1FMKA 2GSBA 4FBNA 3WA4A 3VS7A 2PLDA 2OQ1A 3CXLA 2ETZA 4X6SA 3BUNB 1O4GA 3CWGA 2K7AB 1FBVA 2H5KA 2DCRA 2RMXA 1O4NA 4TZIA 2Y3AB 2CS0A 5BO4A 1GRIA 1FBZA 2AOAA 1RJAA 3M7FA 1K9AA 3VRYA 1O47A 3PS5A 4WWQA 1O42A 2LQNA 1FHSA 2SHPA 1TZEE 1O45A 1JWOA 2RORA 1CWDL 3VGOA 5HKZA 3OB1B 4JEGA 1O4CA 1BHHB 3VS4A 2MRKA 4GPLB 3OP0A 1IJRA 3OB2B 1RPYA 2ECDA 2ABLA 3HHMB 2VIFA 3EAZA 1B47A 3MXYA 3QWYA 2PTKA 1AD5A 4K44A 1O46A 4OHEA 3IMDA 1O4EA 5HKYA 4P9ZA 2LNWA 2MC1A 1JU5A 3HIZB 4DGXA 2IZVA 2HDVA 3VRQA 3QWXX 3PSKA 4D8KA 1A81A 2EYZA 1WQUA 2DLZA 1BFJA 4L1BB 2L3TA 3CD3A 1BM2A 1O4FA 1OPKA 1BLJA 1M61A 3VRRA 1LUNA 1O4OA 1O4DA 4XZ0A 1O44A 3GXXA 1O4MA 4NWGA 4LUDA 2QMSA 2CR4A 3N7YA 1KA7A 1RQQC 2MRJA 2DVJA 4K11A 1KC2A 2MQIA 3HCKA 2AUGA 1KA6A 2OZOA 3VRNA 3VS6A 1X0NA 2HMHA 2CBLA 4E93A 1A1CA 2YU7A
chains in the Genus database with same CATH superfamily
2EO3A 1BHHA 2KNOA 2EU0A 2DX0A 1A08A 2L6KA 5DF6A 5KAZA 1LKLA 3PSJA 1SHDA 1A07A 1O4BA 3BUOB 3BUMB 2CIAA 5DC9A 1AOTF 1TCEA 3GQIB 3K2MA 2YSXA 1UURA 1QCFA 4FL3A 1F2FA 1O49A 1ZFPE 3ZNIA 2EL8A 1I3ZA 3BKBA 1LUIA 4LUEA 1NZLA 4NWFA 3S8OA 2KGYA 1O4LA 4M4ZA 1Y57A 2JYQA 1LKKA 1SPSA 1CSYA 2IUGA 1NRVA 1JYUA 1FYRA 4E68A 2AOBA 1LCKA 1AYAA 2B3OA 3VS5A 3IN8A 1R1PA 2IUIA 3VROA 1Y1UA 3VRPA 3S9KA 2K79B 5DC0B 4QSYA 4GL9E 2PLEA 1O4AA 4XZ1A 3VRZA 5CDWA 1R1QA 1Z3KA 3CBLA 1OO3A 1AYDA 1A1EA 1O48A 3T04A 2EYYA 3PQZA 2BBUA 1O4QA 3N8MA 1FU6A 4F59A 2DLYA 1O4RA 2EKXA 5DC4A 4A4CA 2LRAA 2HDXA 5J3XA 4H1OA 2FO0A 1BMBA 2PNAA 1D4WA 3NHNA 4JE4A 1BG1A 1O4IA 3TKZA 3TL0A 5EHRA 3MXCA 1BFIA 1CJ1A 3VS1A 3VS3A 2RSYA 3IMJA 5GJHA 4U1PA 1P13A 2Y1NA 2C9WA 2EOBA 1JYQA 1X6CA 1CSZA 3BUWB 1LUKA 2C0TA 5IBSA 4JGHA 3C7IA 3K2TA 1O4HA 2EYVA 1O41A 3N84A 4K2RA 1QG1E 1HCSB 5AXIA 1SHAA 1CWEA 2MK2A 3UF4A 1O4JA 1BKMA 3PJPA 5GJIA 2CI8A 1A09A 3OV1A 2RVFA 1R1SA 1LUMA 2KK6A 2EO6A 2LQWA 4OHLA 1QADA 1SKJA 3IN7A 4EY0A 3US4A 5IBMA 4F5AA 2CRHA 1BHFA 2FCIA 2GE9A 1O4PA 1YVLA 4K45A 1X27A 1OPLA 5D0JA 3MAZA 1A1BA 1IS0A 1SPRA 2PNBA 3PFVA 3VS0A 1M27A 3VS2A 1BKLA 5EG3B 1BLKA 3PLFB 3EACA 1KSWA 4DGPA 1G83A 5I6VA 3KFJA 2IUHA 1JYRA 1AOUF 4A4BA 2LCTA 5EELA 2H8HA 3BUXB 1AYCA 5AULA 3OVEA 2CI9A 1AYBA 2HUWA 5EEQA 3UYOA 1AB2A 4H34A 1SHBA 5HKWA 1XA6A 1NZVA 1H9OA 4EIHA 4OHHA 2HCKA 2L4KA 1GHUA 2LNXA 5EHPA 2DM0A 1O4KA 1HCTB 1PICA 1F1WA 2Y1MA 4U17A 4OHDA 4OHIA 1FU5A 4FL2A 1LCJA 3S8NA 2C0IA 1YVHA 4F5BA 4ROJA 4GWFA 1A1AA 2XP1A 2H46E 3GXWA 4P9VA 2SRCA 3S8LA 1MILA 1UUSA 1OO4A 1O43A 1D1ZA 2C0OA 1MW4A 1BF5A 1D4TA 1FMKA 2GSBA 4FBNA 3WA4A 3VS7A 3LYVA 2PLDA 2OQ1A 3CXLA 2ETZA 4X6SA 3BUNB 1O4GA 3CWGA 2K7AB 1FBVA 2H5KA 2DCRA 2RMXA 1O4NA 4TZIA 2Y3AB 2CS0A 5BO4A 1GRIA 1FBZA 2AOAA 1RJAA 3M7FA 1K9AA 3VRYA 1O47A 3PS5A 4WWQA 1O42A 2LQNA 1FHSA 2SHPA 1TZEE 1O45A 1JWOA 2RORA 1CWDL 3VGOA 5HKZA 3OB1B 4JEGA 1O4CA 1BHHB 3VS4A 2MRKA 4GPLB 3OP0A 1IJRA 3OB2B 1RPYA 2ECDA 2ABLA 3HHMB 2VIFA 3EAZA 1B47A 3MXYA 3QWYA 2PTKA 1AD5A 4K44A 1O46A 4OHEA 3IMDA 1O4EA 5HKYA 4P9ZA 2LNWA 2MC1A 1JU5A 3HIZB 4DGXA 2IZVA 2HDVA 3VRQA 3QWXX 3PSKA 4D8KA 1A81A 2EYZA 1WQUA 2DLZA 1BFJA 4L1BB 2L3TA 3CD3A 1BM2A 1O4FA 1OPKA 1BLJA 1M61A 3VRRA 1LUNA 1O4OA 1O4DA 4XZ0A 1O44A 3GXXA 1O4MA 4NWGA 4LUDA 2QMSA 2CR4A 3N7YA 1KA7A 1RQQC 2MRJA 2DVJA 4K11A 1KC2A 2MQIA 3HCKA 2AUGA 1KA6A 2OZOA 3VRNA 3VS6A 1X0NA 2HMHA 2CBLA 4E93A 1A1CA 2YU7A
chains in the Genus database with same CATH topology
2EO3A 1BHHA 2KNOA 2EU0A 2DX0A 1A08A 2L6KA 5DF6A 5KAZA 1LKLA 3PSJA 1SHDA 1A07A 1O4BA 3BUOB 3BUMB 2CIAA 5DC9A 1AOTF 1TCEA 3GQIB 3K2MA 2YSXA 1UURA 1QCFA 4FL3A 1F2FA 1O49A 1ZFPE 3ZNIA 2EL8A 1I3ZA 3BKBA 1LUIA 4LUEA 1NZLA 4NWFA 3S8OA 1O4LA 4M4ZA 1Y57A 2JYQA 1LKKA 1SPSA 1CSYA 2IUGA 1NRVA 1JYUA 1FYRA 4E68A 2AOBA 1LCKA 1AYAA 2B3OA 3VS5A 3IN8A 1R1PA 2IUIA 3VROA 1Y1UA 3VRPA 3S9KA 2K79B 5DC0B 4QSYA 4GL9E 2PLEA 1O4AA 4XZ1A 3VRZA 5CDWA 1R1QA 1Z3KA 3CBLA 1OO3A 1AYDA 1A1EA 1O48A 3T04A 2EYYA 3PQZA 2BBUA 1O4QA 3N8MA 1FU6A 4F59A 2DLYA 1O4RA 2EKXA 5DC4A 4A4CA 2HDXA 5J3XA 4H1OA 2FO0A 1BMBA 2PNAA 1D4WA 3NHNA 4JE4A 1BG1A 1O4IA 3TKZA 3TL0A 5EHRA 3MXCA 1BFIA 1CJ1A 3VS1A 3VS3A 2RSYA 3IMJA 5GJHA 4U1PA 1P13A 2Y1NA 2C9WA 2EOBA 1JYQA 1X6CA 1CSZA 3BUWB 1LUKA 2C0TA 5IBSA 4JGHA 3C7IA 1O4HA 2EYVA 1O41A 3N84A 4K2RA 1QG1E 1HCSB 5AXIA 1SHAA 1CWEA 2MK2A 3UF4A 1O4JA 1BKMA 3PJPA 5GJIA 2CI8A 1A09A 3OV1A 2RVFA 1R1SA 1LUMA 2KK6A 2EO6A 2LQWA 4OHLA 1QADA 1SKJA 3IN7A 4EY0A 3US4A 5IBMA 4F5AA 2CRHA 1BHFA 2FCIA 2GE9A 1O4PA 1YVLA 4K45A 1X27A 1OPLA 5D0JA 3MAZA 1A1BA 1IS0A 1SPRA 2PNBA 3PFVA 3VS0A 1M27A 3VS2A 1BKLA 5EG3B 1BLKA 3PLFB 3EACA 1KSWA 4DGPA 1G83A 5I6VA 3KFJA 2IUHA 1JYRA 1AOUF 4A4BA 2LCTA 5EELA 2H8HA 3BUXB 1AYCA 5AULA 3OVEA 2CI9A 1AYBA 2HUWA 5EEQA 3UYOA 1AB2A 4H34A 1SHBA 5HKWA 1XA6A 1NZVA 1H9OA 4EIHA 4OHHA 2HCKA 2L4KA 1GHUA 2LNXA 5EHPA 2DM0A 1O4KA 1HCTB 1PICA 1F1WA 2Y1MA 4U17A 4OHDA 4OHIA 1FU5A 4FL2A 1LCJA 3S8NA 2C0IA 1YVHA 4F5BA 4ROJA 4GWFA 1A1AA 2XP1A 2H46E 3GXWA 4P9VA 2SRCA 3S8LA 1MILA 1UUSA 1OO4A 1O43A 1D1ZA 2C0OA 1MW4A 1BF5A 1D4TA 1FMKA 2GSBA 4FBNA 3WA4A 3VS7A 2PLDA 2OQ1A 3CXLA 2ETZA 4X6SA 3BUNB 1O4GA 3CWGA 2K7AB 1FBVA 2H5KA 2DCRA 2RMXA 1O4NA 4TZIA 2Y3AB 2CS0A 5BO4A 1GRIA 1FBZA 2AOAA 1RJAA 3M7FA 1K9AA 3VRYA 1O47A 3PS5A 4WWQA 1O42A 2LQNA 1FHSA 2SHPA 1TZEE 1O45A 1JWOA 2RORA 1CWDL 3VGOA 5HKZA 3OB1B 4JEGA 1O4CA 1BHHB 3VS4A 2MRKA 4GPLB 3OP0A 1IJRA 3OB2B 1RPYA 2ECDA 2ABLA 3HHMB 2VIFA 3EAZA 1B47A 3MXYA 3QWYA 2PTKA 1AD5A 4K44A 1O46A 4OHEA 3IMDA 1O4EA 5HKYA 4P9ZA 2LNWA 2MC1A 1JU5A 3HIZB 4DGXA 2IZVA 2HDVA 3VRQA 3QWXX 3PSKA 4D8KA 1A81A 2EYZA 1WQUA 2DLZA 1BFJA 4L1BB 2L3TA 3CD3A 1BM2A 1O4FA 1OPKA 1BLJA 1M61A 3VRRA 1LUNA 1O4OA 1O4DA 4XZ0A 1O44A 3GXXA 1O4MA 4NWGA 4LUDA 2QMSA 2CR4A 3N7YA 1KA7A 1RQQC 2MRJA 2DVJA 4K11A 1KC2A 2MQIA 3HCKA 2AUGA 1KA6A 2OZOA 3VRNA 3VS6A 1X0NA 2HMHA 2CBLA 4E93A 1A1CA 2YU7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EO3 A;  1BHH A;  2KNO A;  2EU0 A;  2DX0 A;  1A08 A;  2L6K A;  5DF6 A;  5KAZ A;  1LKL A;  3PSJ A;  1SHD A;  1A07 A;  1O4B A;  3BUO B;  3BUM B;  2CIA A;  5DC9 A;  1AOT F;  1TCE A;  3GQI B;  3K2M A;  2YSX A;  1UUR A;  1QCF A;  4FL3 A;  1F2F A;  1O49 A;  1ZFP E;  3ZNI A;  2EL8 A;  1I3Z A;  3BKB A;  1LUI A;  4LUE A;  1NZL A;  4NWF A;  3S8O A;  1O4L A;  4M4Z A;  1Y57 A;  2JYQ A;  1LKK A;  1SPS A;  1CSY A;  2IUG A;  1NRV A;  1JYU A;  1FYR A;  4E68 A;  2AOB A;  1LCK A;  1AYA A;  2B3O A;  3VS5 A;  3IN8 A;  1R1P A;  2IUI A;  3VRO A;  1Y1U A;  3VRP A;  3S9K A;  2K79 B;  5DC0 B;  4QSY A;  4GL9 E;  2PLE A;  1O4A A;  4XZ1 A;  3VRZ A;  5CDW A;  1R1Q A;  1Z3K A;  3CBL A;  1OO3 A;  1AYD A;  1A1E A;  1O48 A;  3T04 A;  2EYY A;  3PQZ A;  2BBU A;  1O4Q A;  3N8M A;  1FU6 A;  4F59 A;  2DLY A;  1O4R A;  2EKX A;  5DC4 A;  4A4C A;  2HDX A;  5J3X A;  4H1O A;  2FO0 A;  1BMB A;  2PNA A;  1D4W A;  3NHN A;  4JE4 A;  1BG1 A;  1O4I A;  3TKZ A;  3TL0 A;  5EHR A;  3MXC A;  1BFI A;  1CJ1 A;  3VS1 A;  3VS3 A;  2RSY A;  3IMJ A;  5GJH A;  4U1P A;  1P13 A;  2Y1N A;  2C9W A;  2EOB A;  1JYQ A;  1X6C A;  1CSZ A;  3BUW B;  1LUK A;  2C0T A;  5IBS A;  4JGH A;  3C7I A;  1O4H A;  2EYV A;  1O41 A;  3N84 A;  4K2R A;  1QG1 E;  1HCS B;  5AXI A;  1SHA A;  1CWE A;  2MK2 A;  3UF4 A;  1O4J A;  1BKM A;  3PJP A;  5GJI A;  2CI8 A;  1A09 A;  3OV1 A;  2RVF A;  1R1S A;  1LUM A;  2KK6 A;  2EO6 A;  2LQW A;  4OHL A;  1QAD A;  1SKJ A;  3IN7 A;  4EY0 A;  3US4 A;  5IBM A;  4F5A A;  2CRH A;  1BHF A;  2FCI A;  2GE9 A;  1O4P A;  1YVL A;  4K45 A;  1X27 A;  1OPL A;  5D0J A;  3MAZ A;  1A1B A;  1IS0 A;  1SPR A;  2PNB A;  3PFV A;  3VS0 A;  1M27 A;  3VS2 A;  1BKL A;  5EG3 B;  1BLK A;  3PLF B;  3EAC A;  1KSW A;  4DGP A;  1G83 A;  5I6V A;  3KFJ A;  2IUH A;  1JYR A;  1AOU F;  4A4B A;  2LCT A;  5EEL A;  2H8H A;  3BUX B;  1AYC A;  5AUL A;  3OVE A;  2CI9 A;  1AYB A;  2HUW A;  5EEQ A;  3UYO A;  1AB2 A;  4H34 A;  1SHB A;  5HKW A;  1XA6 A;  1NZV A;  1H9O A;  4EIH A;  4OHH A;  2HCK A;  2L4K A;  1GHU A;  2LNX A;  5EHP A;  2DM0 A;  1O4K A;  1HCT B;  1PIC A;  1F1W A;  2Y1M A;  4U17 A;  4OHD A;  4OHI A;  1FU5 A;  4FL2 A;  1LCJ A;  3S8N A;  2C0I A;  1YVH A;  4F5B A;  4ROJ A;  4GWF A;  1A1A A;  2XP1 A;  2H46 E;  3GXW A;  4P9V A;  2SRC A;  3S8L A;  1MIL A;  1UUS A;  1OO4 A;  1O43 A;  1D1Z A;  2C0O A;  1MW4 A;  1BF5 A;  1D4T A;  1FMK A;  2GSB A;  4FBN A;  3WA4 A;  3VS7 A;  2PLD A;  2OQ1 A;  3CXL A;  2ETZ A;  4X6S A;  3BUN B;  1O4G A;  3CWG A;  2K7A B;  1FBV A;  2H5K A;  2DCR A;  2RMX A;  1O4N A;  4TZI A;  2Y3A B;  2CS0 A;  5BO4 A;  1GRI A;  1FBZ A;  2AOA A;  1RJA A;  3M7F A;  1K9A A;  3VRY A;  1O47 A;  3PS5 A;  4WWQ A;  1O42 A;  2LQN A;  1FHS A;  2SHP A;  1TZE E;  1O45 A;  1JWO A;  2ROR A;  1CWD L;  3VGO A;  5HKZ A;  3OB1 B;  4JEG A;  1O4C A;  1BHH B;  3VS4 A;  2MRK A;  4GPL B;  3OP0 A;  1IJR A;  3OB2 B;  1RPY A;  2ECD A;  2ABL A;  3HHM B;  2VIF A;  3EAZ A;  1B47 A;  3MXY A;  3QWY A;  2PTK A;  1AD5 A;  4K44 A;  1O46 A;  4OHE A;  3IMD A;  1O4E A;  5HKY A;  4P9Z A;  2LNW A;  2MC1 A;  1JU5 A;  3HIZ B;  4DGX A;  2IZV A;  2HDV A;  3VRQ A;  3QWX X;  3PSK A;  4D8K A;  1A81 A;  2EYZ A;  1WQU A;  2DLZ A;  1BFJ A;  4L1B B;  2L3T A;  3CD3 A;  1BM2 A;  1O4F A;  1OPK A;  1BLJ A;  1M61 A;  3VRR A;  1LUN A;  1O4O A;  1O4D A;  4XZ0 A;  1O44 A;  3GXX A;  1O4M A;  4NWG A;  4LUD A;  2QMS A;  2CR4 A;  3N7Y A;  1KA7 A;  1RQQ C;  2MRJ A;  2DVJ A;  4K11 A;  1KC2 A;  2MQI A;  3HCK A;  2AUG A;  1KA6 A;  2OZO A;  3VRN A;  3VS6 A;  1X0N A;  2HMH A;  2CBL A;  4E93 A;  1A1C A;  2YU7 A; 
#chains in the Genus database with same CATH topology
 2EO3 A;  1BHH A;  2KNO A;  2EU0 A;  2DX0 A;  1A08 A;  2L6K A;  5DF6 A;  5KAZ A;  1LKL A;  3PSJ A;  1SHD A;  1A07 A;  1O4B A;  3BUO B;  3BUM B;  2CIA A;  5DC9 A;  1AOT F;  1TCE A;  3GQI B;  3K2M A;  2YSX A;  1UUR A;  1QCF A;  4FL3 A;  1F2F A;  1O49 A;  1ZFP E;  3ZNI A;  2EL8 A;  1I3Z A;  3BKB A;  1LUI A;  4LUE A;  1NZL A;  4NWF A;  3S8O A;  2KGY A;  1O4L A;  4M4Z A;  1Y57 A;  2JYQ A;  1LKK A;  1SPS A;  1CSY A;  2IUG A;  1NRV A;  1JYU A;  1FYR A;  4E68 A;  2AOB A;  1LCK A;  1AYA A;  2B3O A;  3VS5 A;  3IN8 A;  1R1P A;  2IUI A;  3VRO A;  1Y1U A;  3VRP A;  3S9K A;  2K79 B;  5DC0 B;  4QSY A;  4GL9 E;  2PLE A;  1O4A A;  4XZ1 A;  3VRZ A;  5CDW A;  1R1Q A;  1Z3K A;  3CBL A;  1OO3 A;  1AYD A;  1A1E A;  1O48 A;  3T04 A;  2EYY A;  3PQZ A;  2BBU A;  1O4Q A;  3N8M A;  1FU6 A;  4F59 A;  2DLY A;  1O4R A;  2EKX A;  5DC4 A;  4A4C A;  2LRA A;  2HDX A;  5J3X A;  4H1O A;  2FO0 A;  1BMB A;  2PNA A;  1D4W A;  3NHN A;  4JE4 A;  1BG1 A;  1O4I A;  3TKZ A;  3TL0 A;  5EHR A;  3MXC A;  1BFI A;  1CJ1 A;  3VS1 A;  3VS3 A;  2RSY A;  3IMJ A;  5GJH A;  4U1P A;  1P13 A;  2Y1N A;  2C9W A;  2EOB A;  1JYQ A;  1X6C A;  1CSZ A;  3BUW B;  1LUK A;  2C0T A;  5IBS A;  4JGH A;  3C7I A;  3K2T A;  1O4H A;  2EYV A;  1O41 A;  3N84 A;  4K2R A;  1QG1 E;  1HCS B;  5AXI A;  1SHA A;  1CWE A;  2MK2 A;  3UF4 A;  1O4J A;  1BKM A;  3PJP A;  5GJI A;  2CI8 A;  1A09 A;  3OV1 A;  2RVF A;  1R1S A;  1LUM A;  2KK6 A;  2EO6 A;  2LQW A;  4OHL A;  1QAD A;  1SKJ A;  3IN7 A;  4EY0 A;  3US4 A;  5IBM A;  4F5A A;  2CRH A;  1BHF A;  2FCI A;  2GE9 A;  1O4P A;  1YVL A;  4K45 A;  1X27 A;  1OPL A;  5D0J A;  3MAZ A;  1A1B A;  1IS0 A;  1SPR A;  2PNB A;  3PFV A;  3VS0 A;  1M27 A;  3VS2 A;  1BKL A;  5EG3 B;  1BLK A;  3PLF B;  3EAC A;  1KSW A;  4DGP A;  1G83 A;  5I6V A;  3KFJ A;  2IUH A;  1JYR A;  1AOU F;  4A4B A;  2LCT A;  5EEL A;  2H8H A;  3BUX B;  1AYC A;  5AUL A;  3OVE A;  2CI9 A;  1AYB A;  2HUW A;  5EEQ A;  3UYO A;  1AB2 A;  4H34 A;  1SHB A;  5HKW A;  1XA6 A;  1NZV A;  1H9O A;  4EIH A;  4OHH A;  2HCK A;  2L4K A;  1GHU A;  2LNX A;  5EHP A;  2DM0 A;  1O4K A;  1HCT B;  1PIC A;  1F1W A;  2Y1M A;  4U17 A;  4OHD A;  4OHI A;  1FU5 A;  4FL2 A;  1LCJ A;  3S8N A;  2C0I A;  1YVH A;  4F5B A;  4ROJ A;  4GWF A;  1A1A A;  2XP1 A;  2H46 E;  3GXW A;  4P9V A;  2SRC A;  3S8L A;  1MIL A;  1UUS A;  1OO4 A;  1O43 A;  1D1Z A;  2C0O A;  1MW4 A;  1BF5 A;  1D4T A;  1FMK A;  2GSB A;  4FBN A;  3WA4 A;  3VS7 A;  3LYV A;  2PLD A;  2OQ1 A;  3CXL A;  2ETZ A;  4X6S A;  3BUN B;  1O4G A;  3CWG A;  2K7A B;  1FBV A;  2H5K A;  2DCR A;  2RMX A;  1O4N A;  4TZI A;  2Y3A B;  2CS0 A;  5BO4 A;  1GRI A;  1FBZ A;  2AOA A;  1RJA A;  3M7F A;  1K9A A;  3VRY A;  1O47 A;  3PS5 A;  4WWQ A;  1O42 A;  2LQN A;  1FHS A;  2SHP A;  1TZE E;  1O45 A;  1JWO A;  2ROR A;  1CWD L;  3VGO A;  5HKZ A;  3OB1 B;  4JEG A;  1O4C A;  1BHH B;  3VS4 A;  2MRK A;  4GPL B;  3OP0 A;  1IJR A;  3OB2 B;  1RPY A;  2ECD A;  2ABL A;  3HHM B;  2VIF A;  3EAZ A;  1B47 A;  3MXY A;  3QWY A;  2PTK A;  1AD5 A;  4K44 A;  1O46 A;  4OHE A;  3IMD A;  1O4E A;  5HKY A;  4P9Z A;  2LNW A;  2MC1 A;  1JU5 A;  3HIZ B;  4DGX A;  2IZV A;  2HDV A;  3VRQ A;  3QWX X;  3PSK A;  4D8K A;  1A81 A;  2EYZ A;  1WQU A;  2DLZ A;  1BFJ A;  4L1B B;  2L3T A;  3CD3 A;  1BM2 A;  1O4F A;  1OPK A;  1BLJ A;  1M61 A;  3VRR A;  1LUN A;  1O4O A;  1O4D A;  4XZ0 A;  1O44 A;  3GXX A;  1O4M A;  4NWG A;  4LUD A;  2QMS A;  2CR4 A;  3N7Y A;  1KA7 A;  1RQQ C;  2MRJ A;  2DVJ A;  4K11 A;  1KC2 A;  2MQI A;  3HCK A;  2AUG A;  1KA6 A;  2OZO A;  3VRN A;  3VS6 A;  1X0N A;  2HMH A;  2CBL A;  4E93 A;  1A1C A;  2YU7 A; 
#chains in the Genus database with same CATH homology
 2EO3 A;  1BHH A;  2KNO A;  2EU0 A;  2DX0 A;  1A08 A;  2L6K A;  5DF6 A;  5KAZ A;  1LKL A;  3PSJ A;  1SHD A;  1A07 A;  1O4B A;  3BUO B;  3BUM B;  2CIA A;  5DC9 A;  1AOT F;  1TCE A;  3GQI B;  3K2M A;  2YSX A;  1UUR A;  1QCF A;  4FL3 A;  1F2F A;  1O49 A;  1ZFP E;  3ZNI A;  2EL8 A;  1I3Z A;  3BKB A;  1LUI A;  4LUE A;  1NZL A;  4NWF A;  3S8O A;  1O4L A;  4M4Z A;  1Y57 A;  2JYQ A;  1LKK A;  1SPS A;  1CSY A;  2IUG A;  1NRV A;  1JYU A;  1FYR A;  4E68 A;  2AOB A;  1LCK A;  1AYA A;  2B3O A;  3VS5 A;  3IN8 A;  1R1P A;  2IUI A;  3VRO A;  1Y1U A;  3VRP A;  3S9K A;  2K79 B;  5DC0 B;  4QSY A;  4GL9 E;  2PLE A;  1O4A A;  4XZ1 A;  3VRZ A;  5CDW A;  1R1Q A;  1Z3K A;  3CBL A;  1OO3 A;  1AYD A;  1A1E A;  1O48 A;  3T04 A;  2EYY A;  3PQZ A;  2BBU A;  1O4Q A;  3N8M A;  1FU6 A;  4F59 A;  2DLY A;  1O4R A;  2EKX A;  5DC4 A;  4A4C A;  2HDX A;  5J3X A;  4H1O A;  2FO0 A;  1BMB A;  2PNA A;  1D4W A;  3NHN A;  4JE4 A;  1BG1 A;  1O4I A;  3TKZ A;  3TL0 A;  5EHR A;  3MXC A;  1BFI A;  1CJ1 A;  3VS1 A;  3VS3 A;  2RSY A;  3IMJ A;  5GJH A;  4U1P A;  1P13 A;  2Y1N A;  2C9W A;  2EOB A;  1JYQ A;  1X6C A;  1CSZ A;  3BUW B;  1LUK A;  2C0T A;  5IBS A;  4JGH A;  3C7I A;  1O4H A;  2EYV A;  1O41 A;  3N84 A;  4K2R A;  1QG1 E;  1HCS B;  5AXI A;  1SHA A;  1CWE A;  2MK2 A;  3UF4 A;  1O4J A;  1BKM A;  3PJP A;  5GJI A;  2CI8 A;  1A09 A;  3OV1 A;  2RVF A;  1R1S A;  1LUM A;  2KK6 A;  2EO6 A;  2LQW A;  4OHL A;  1QAD A;  1SKJ A;  3IN7 A;  4EY0 A;  3US4 A;  5IBM A;  4F5A A;  2CRH A;  1BHF A;  2FCI A;  2GE9 A;  1O4P A;  1YVL A;  4K45 A;  1X27 A;  1OPL A;  5D0J A;  3MAZ A;  1A1B A;  1IS0 A;  1SPR A;  2PNB A;  3PFV A;  3VS0 A;  1M27 A;  3VS2 A;  1BKL A;  5EG3 B;  1BLK A;  3PLF B;  3EAC A;  1KSW A;  4DGP A;  1G83 A;  5I6V A;  3KFJ A;  2IUH A;  1JYR A;  1AOU F;  4A4B A;  2LCT A;  5EEL A;  2H8H A;  3BUX B;  1AYC A;  5AUL A;  3OVE A;  2CI9 A;  1AYB A;  2HUW A;  5EEQ A;  3UYO A;  1AB2 A;  4H34 A;  1SHB A;  5HKW A;  1XA6 A;  1NZV A;  1H9O A;  4EIH A;  4OHH A;  2HCK A;  2L4K A;  1GHU A;  2LNX A;  5EHP A;  2DM0 A;  1O4K A;  1HCT B;  1PIC A;  1F1W A;  2Y1M A;  4U17 A;  4OHD A;  4OHI A;  1FU5 A;  4FL2 A;  1LCJ A;  3S8N A;  2C0I A;  1YVH A;  4F5B A;  4ROJ A;  4GWF A;  1A1A A;  2XP1 A;  2H46 E;  3GXW A;  4P9V A;  2SRC A;  3S8L A;  1MIL A;  1UUS A;  1OO4 A;  1O43 A;  1D1Z A;  2C0O A;  1MW4 A;  1BF5 A;  1D4T A;  1FMK A;  2GSB A;  4FBN A;  3WA4 A;  3VS7 A;  2PLD A;  2OQ1 A;  3CXL A;  2ETZ A;  4X6S A;  3BUN B;  1O4G A;  3CWG A;  2K7A B;  1FBV A;  2H5K A;  2DCR A;  2RMX A;  1O4N A;  4TZI A;  2Y3A B;  2CS0 A;  5BO4 A;  1GRI A;  1FBZ A;  2AOA A;  1RJA A;  3M7F A;  1K9A A;  3VRY A;  1O47 A;  3PS5 A;  4WWQ A;  1O42 A;  2LQN A;  1FHS A;  2SHP A;  1TZE E;  1O45 A;  1JWO A;  2ROR A;  1CWD L;  3VGO A;  5HKZ A;  3OB1 B;  4JEG A;  1O4C A;  1BHH B;  3VS4 A;  2MRK A;  4GPL B;  3OP0 A;  1IJR A;  3OB2 B;  1RPY A;  2ECD A;  2ABL A;  3HHM B;  2VIF A;  3EAZ A;  1B47 A;  3MXY A;  3QWY A;  2PTK A;  1AD5 A;  4K44 A;  1O46 A;  4OHE A;  3IMD A;  1O4E A;  5HKY A;  4P9Z A;  2LNW A;  2MC1 A;  1JU5 A;  3HIZ B;  4DGX A;  2IZV A;  2HDV A;  3VRQ A;  3QWX X;  3PSK A;  4D8K A;  1A81 A;  2EYZ A;  1WQU A;  2DLZ A;  1BFJ A;  4L1B B;  2L3T A;  3CD3 A;  1BM2 A;  1O4F A;  1OPK A;  1BLJ A;  1M61 A;  3VRR A;  1LUN A;  1O4O A;  1O4D A;  4XZ0 A;  1O44 A;  3GXX A;  1O4M A;  4NWG A;  4LUD A;  2QMS A;  2CR4 A;  3N7Y A;  1KA7 A;  1RQQ C;  2MRJ A;  2DVJ A;  4K11 A;  1KC2 A;  2MQI A;  3HCK A;  2AUG A;  1KA6 A;  2OZO A;  3VRN A;  3VS6 A;  1X0N A;  2HMH A;  2CBL A;  4E93 A;  1A1C A;  2YU7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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