1O4KA

Crystal structure of sh2 in complex with pasbn.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4kA00
1LKKA 1R1PA 2DCRA 2L6KA 4XZ0A 4A4BA 1SKJA 1R1QA 5DC9A 3S8NA 3WA4A 1A09A 1BM2A 3TKZA 3VGOA 2MRKA 3OVEA 3BUMB 1FMKA 3HCKA 2MK2A 1LKLA 5GJHA 3OB1B 5IBMA 2B3OA 2GE9A 3IN7A 5I6VA 2EYYA 2PNBA 1FBZA 5HKZA 1JWOA 3QWXX 4K11A 5HKWA 4FL2A 2EO3A 1NRVA 2L4KA 2PTKA 1H9OA 4EIHA 1LCJA 4FL3A 4U17A 1BF5A 2PNAA 4E68A 3UF4A 2VIFA 1QG1E 2YSXA 4K45A 1AYCA 5EHRA 2FO0A 3IMDA 2KNOA 3VRPA 2LQWA 2IUIA 5AULA 1O42A 1O45A 1SPRA 1A81A 2GSBA 3VS4A 1HCSB 2IUHA 4OHIA 1JYUA 3KFJA 5EELA 1O4KA 4E93A 1LCKA 1Y1UA 2CI8A 1X27A 2ABLA 4LUDA 1O47A 1CJ1A 4A4CA 1O4FA 2EL8A 1TZEE 2LQNA 1BFJA 1O4MA 2OQ1A 3N7YA 3PQZA 3VS7A 5DC4A 2Y1NA 3UYOA 2CRHA 1A1EA 5DC0B 4DGPA 1O4HA 3MAZA 4H34A 1B47A 4F59A 2OZOA 2XP1A 1SPSA 2SHPA 2CIAA 2EU0A 5J3XA 3VRRA 1O44A 2EOBA 4XZ1A 1YVHA 1JYRA 1BMBA 1SHDA 1IJRA 4U1PA 2MC1A 1AOUF 1O4BA 2HMHA 2BBUA 2QMSA 1O43A 2MRJA 2K79B 2C0TA 2ECDA 1KSWA 4P9VA 4JEGA 1X6CA 1BKMA 4D8KA 3S9KA 1XA6A 4TZIA 2PLDA 4X6SA 1D4TA 4H1OA 1D1ZA 1LUIA 4GWFA 3VS0A 2JYQA 1OPLA 3PS5A 3US4A 1OO4A 2C0OA 1MW4A 1M27A 2C9WA 1AB2A 2IUGA 4QSYA 2Y3AB 5EHPA 1YVLA 2AOBA 3MXCA 5EG3B 1SHBA 3IMJA 2DLYA 1F1WA 3OB2B 1A1CA 3PJPA 2FCIA 3VROA 1BHHB 1RQQC 3S8OA 2HDVA 1BHHA 3CWGA 3S8LA 1BHFA 1QADA 5DF6A 3VRZA 2LCTA 1O4RA 2Y1MA 3VRYA 5KAZA 2AOAA 2RORA 2RMXA 3TL0A 1FYRA 4K44A 2EKXA 5GJIA 1O4LA 3EACA 2EYVA 1SHAA 4ROJA 2AUGA 2MQIA 1I3ZA 3ZNIA 3BUNB 2RVFA 1BKLA 5BO4A 1AYBA 4M4ZA 2DM0A 1FU6A 4DGXA 3OP0A 1O4NA 3GXXA 2RSYA 1LUNA 2DVJA 2H5KA 3VRQA 3VS1A 1O46A 1O4PA 3VS3A 3BUXB 4OHDA 1KA7A 3HHMB 3VS2A 1AYAA 1BLKA 2YU7A 2HCKA 4FBNA 1O4IA 1GHUA 3EAZA 2SRCA 3M7FA 1QCFA 2CS0A 1O4QA 4JE4A 1O4DA 2K7AB 3BUOB 5D0JA 1O41A 3CBLA 3GQIB 4OHHA 5AXIA 3T04A 2CR4A 1BG1A 4OHEA 2HUWA 1FHSA 1UUSA 1O4CA 1Y57A 1A1AA 1HCTB 1UURA 4OHLA 1JYQA 4NWFA 5IBSA 1KC2A 1CSZA 4GPLB 1X0NA 1IS0A 1O4AA 3VS5A 3PFVA 4L1BB 3C7IA 1M61A 2DLZA 3IN8A 2EO6A 1CWDL 1F2FA 1K9AA 2H8HA 2EYZA 1O49A 4WWQA 1AOTF 1WQUA 4K2RA 1LUKA 4NWGA 1P13A 1MILA 3CXLA 1BFIA 4GL9E 3GXWA 4JGHA 2DX0A 1PICA 1ZFPE 1AYDA 2KK6A 1JU5A 1O4OA 1O4GA 1AD5A 5CDWA 1A07A 3PSKA 3CD3A 1OPKA 3NHNA 3VRNA 1A08A 3OV1A 1O48A 1G83A 4F5AA 1BLJA 1CWEA 1GRIA 2CI9A 1CSYA 1RJAA 5EEQA 2CBLA 1O4JA 2PLEA 1A1BA 4F5BA 1LUMA 2IZVA 3PSJA 1O4EA 2LNWA 3BKBA 1Z3KA 1KA6A 2LNXA 1RPYA 1R1SA 3BUWB 3QWYA 3N84A 1NZLA 3N8MA 1NZVA 2C0IA 1FBVA 1D4WA 1OO3A 3MXYA 2L3TA 3HIZB 3PLFB 5HKYA 2ETZA 4EY0A 2H46E 4LUEA 1TCEA 2HDXA 4P9ZA 1FU5A 3K2MA 3VS6A
chains in the Genus database with same CATH superfamily
1LKKA 1R1PA 2DCRA 2L6KA 4XZ0A 4A4BA 1SKJA 1R1QA 5DC9A 3S8NA 3WA4A 1A09A 1BM2A 3TKZA 3VGOA 2MRKA 3OVEA 3BUMB 1FMKA 3HCKA 2MK2A 1LKLA 5GJHA 3OB1B 5IBMA 2B3OA 2GE9A 3IN7A 5I6VA 2EYYA 2PNBA 1FBZA 5HKZA 1JWOA 3QWXX 4K11A 5HKWA 4FL2A 2EO3A 1NRVA 2L4KA 2PTKA 1H9OA 4EIHA 1LCJA 4FL3A 4U17A 1BF5A 2KGYA 2PNAA 4E68A 3UF4A 2VIFA 1QG1E 2YSXA 4K45A 1AYCA 5EHRA 2FO0A 3IMDA 2KNOA 3VRPA 2LQWA 2IUIA 5AULA 1O42A 1O45A 1SPRA 1A81A 2GSBA 3VS4A 1HCSB 2IUHA 4OHIA 1JYUA 3KFJA 5EELA 1O4KA 4E93A 1LCKA 1Y1UA 2CI8A 1X27A 2ABLA 4LUDA 1O47A 1CJ1A 4A4CA 1O4FA 2EL8A 1TZEE 2LQNA 1BFJA 1O4MA 2OQ1A 3N7YA 3PQZA 3VS7A 5DC4A 2Y1NA 3UYOA 2CRHA 1A1EA 5DC0B 4DGPA 1O4HA 3MAZA 4H34A 1B47A 4F59A 2OZOA 2XP1A 1SPSA 2SHPA 2CIAA 2EU0A 5J3XA 3VRRA 1O44A 2EOBA 4XZ1A 1YVHA 1JYRA 1BMBA 1SHDA 1IJRA 4U1PA 2MC1A 1AOUF 1O4BA 2HMHA 2BBUA 2QMSA 1O43A 2MRJA 2K79B 2C0TA 2ECDA 1KSWA 4P9VA 4JEGA 1X6CA 1BKMA 4D8KA 3S9KA 1XA6A 4TZIA 2PLDA 4X6SA 1D4TA 4H1OA 1D1ZA 1LUIA 4GWFA 3VS0A 2JYQA 1OPLA 3PS5A 3US4A 1OO4A 2C0OA 1MW4A 1M27A 2C9WA 1AB2A 2IUGA 4QSYA 2Y3AB 5EHPA 1YVLA 2AOBA 3K2TA 3MXCA 5EG3B 1SHBA 3IMJA 2DLYA 1F1WA 3OB2B 1A1CA 3PJPA 2FCIA 3VROA 1BHHB 1RQQC 3S8OA 2HDVA 1BHHA 3CWGA 3S8LA 1BHFA 1QADA 5DF6A 3VRZA 2LCTA 1O4RA 2Y1MA 3VRYA 5KAZA 2AOAA 2RORA 2RMXA 3TL0A 1FYRA 4K44A 2EKXA 5GJIA 1O4LA 3EACA 2EYVA 1SHAA 4ROJA 2AUGA 2MQIA 1I3ZA 3ZNIA 3BUNB 2RVFA 1BKLA 5BO4A 1AYBA 4M4ZA 3LYVA 2DM0A 1FU6A 4DGXA 3OP0A 1O4NA 3GXXA 2RSYA 1LUNA 2DVJA 2H5KA 3VRQA 3VS1A 1O46A 1O4PA 3VS3A 3BUXB 4OHDA 1KA7A 3HHMB 3VS2A 1AYAA 1BLKA 2YU7A 2HCKA 4FBNA 1O4IA 1GHUA 3EAZA 2SRCA 3M7FA 1QCFA 2CS0A 1O4QA 4JE4A 1O4DA 2K7AB 3BUOB 5D0JA 1O41A 3CBLA 3GQIB 4OHHA 5AXIA 3T04A 2CR4A 1BG1A 4OHEA 2HUWA 1FHSA 1UUSA 1O4CA 1Y57A 1A1AA 1HCTB 1UURA 4OHLA 1JYQA 4NWFA 5IBSA 1KC2A 1CSZA 4GPLB 1X0NA 1IS0A 1O4AA 3VS5A 3PFVA 4L1BB 3C7IA 1M61A 2DLZA 2LRAA 3IN8A 2EO6A 1CWDL 1F2FA 1K9AA 2H8HA 2EYZA 1O49A 4WWQA 1AOTF 1WQUA 4K2RA 1LUKA 4NWGA 1P13A 1MILA 3CXLA 1BFIA 4GL9E 3GXWA 4JGHA 2DX0A 1PICA 1ZFPE 1AYDA 2KK6A 1JU5A 1O4OA 1O4GA 1AD5A 5CDWA 1A07A 3PSKA 3CD3A 1OPKA 3NHNA 3VRNA 1A08A 3OV1A 1O48A 1G83A 4F5AA 1BLJA 1CWEA 1GRIA 2CI9A 1CSYA 1RJAA 5EEQA 2CBLA 1O4JA 2PLEA 1A1BA 4F5BA 1LUMA 2IZVA 3PSJA 1O4EA 2LNWA 3BKBA 1Z3KA 1KA6A 2LNXA 1RPYA 1R1SA 3BUWB 3QWYA 3N84A 1NZLA 3N8MA 1NZVA 2C0IA 1FBVA 1D4WA 1OO3A 3MXYA 2L3TA 3HIZB 3PLFB 5HKYA 2ETZA 4EY0A 2H46E 4LUEA 1TCEA 2HDXA 4P9ZA 1FU5A 3K2MA 3VS6A
chains in the Genus database with same CATH topology
1LKKA 1R1PA 2DCRA 2L6KA 4XZ0A 4A4BA 1SKJA 1R1QA 5DC9A 3S8NA 3WA4A 1A09A 1BM2A 3TKZA 3VGOA 2MRKA 3OVEA 3BUMB 1FMKA 3HCKA 2MK2A 1LKLA 5GJHA 3OB1B 5IBMA 2B3OA 2GE9A 3IN7A 5I6VA 2EYYA 2PNBA 1FBZA 5HKZA 1JWOA 3QWXX 4K11A 5HKWA 4FL2A 2EO3A 1NRVA 2L4KA 2PTKA 1H9OA 4EIHA 1LCJA 4FL3A 4U17A 1BF5A 2PNAA 4E68A 3UF4A 2VIFA 1QG1E 2YSXA 4K45A 1AYCA 5EHRA 2FO0A 3IMDA 2KNOA 3VRPA 2LQWA 2IUIA 5AULA 1O42A 1O45A 1SPRA 1A81A 2GSBA 3VS4A 1HCSB 2IUHA 4OHIA 1JYUA 3KFJA 5EELA 1O4KA 4E93A 1LCKA 1Y1UA 2CI8A 1X27A 2ABLA 4LUDA 1O47A 1CJ1A 4A4CA 1O4FA 2EL8A 1TZEE 2LQNA 1BFJA 1O4MA 2OQ1A 3N7YA 3PQZA 3VS7A 5DC4A 2Y1NA 3UYOA 2CRHA 1A1EA 5DC0B 4DGPA 1O4HA 3MAZA 4H34A 1B47A 4F59A 2OZOA 2XP1A 1SPSA 2SHPA 2CIAA 2EU0A 5J3XA 3VRRA 1O44A 2EOBA 4XZ1A 1YVHA 1JYRA 1BMBA 1SHDA 1IJRA 4U1PA 2MC1A 1AOUF 1O4BA 2HMHA 2BBUA 2QMSA 1O43A 2MRJA 2K79B 2C0TA 2ECDA 1KSWA 4P9VA 4JEGA 1X6CA 1BKMA 4D8KA 3S9KA 1XA6A 4TZIA 2PLDA 4X6SA 1D4TA 4H1OA 1D1ZA 1LUIA 4GWFA 3VS0A 2JYQA 1OPLA 3PS5A 3US4A 1OO4A 2C0OA 1MW4A 1M27A 2C9WA 1AB2A 2IUGA 4QSYA 2Y3AB 5EHPA 1YVLA 2AOBA 3MXCA 5EG3B 1SHBA 3IMJA 2DLYA 1F1WA 3OB2B 1A1CA 3PJPA 2FCIA 3VROA 1BHHB 1RQQC 3S8OA 2HDVA 1BHHA 3CWGA 3S8LA 1BHFA 1QADA 5DF6A 3VRZA 2LCTA 1O4RA 2Y1MA 3VRYA 5KAZA 2AOAA 2RORA 2RMXA 3TL0A 1FYRA 4K44A 2EKXA 5GJIA 1O4LA 3EACA 2EYVA 1SHAA 4ROJA 2AUGA 2MQIA 1I3ZA 3ZNIA 3BUNB 2RVFA 1BKLA 5BO4A 1AYBA 4M4ZA 2DM0A 1FU6A 4DGXA 3OP0A 1O4NA 3GXXA 2RSYA 1LUNA 2DVJA 2H5KA 3VRQA 3VS1A 1O46A 1O4PA 3VS3A 3BUXB 4OHDA 1KA7A 3HHMB 3VS2A 1AYAA 1BLKA 2YU7A 2HCKA 4FBNA 1O4IA 1GHUA 3EAZA 2SRCA 3M7FA 1QCFA 2CS0A 1O4QA 4JE4A 1O4DA 2K7AB 3BUOB 5D0JA 1O41A 3CBLA 3GQIB 4OHHA 5AXIA 3T04A 2CR4A 1BG1A 4OHEA 2HUWA 1FHSA 1UUSA 1O4CA 1Y57A 1A1AA 1HCTB 1UURA 4OHLA 1JYQA 4NWFA 5IBSA 1KC2A 1CSZA 4GPLB 1X0NA 1IS0A 1O4AA 3VS5A 3PFVA 4L1BB 3C7IA 1M61A 2DLZA 3IN8A 2EO6A 1CWDL 1F2FA 1K9AA 2H8HA 2EYZA 1O49A 4WWQA 1AOTF 1WQUA 4K2RA 1LUKA 4NWGA 1P13A 1MILA 3CXLA 1BFIA 4GL9E 3GXWA 4JGHA 2DX0A 1PICA 1ZFPE 1AYDA 2KK6A 1JU5A 1O4OA 1O4GA 1AD5A 5CDWA 1A07A 3PSKA 3CD3A 1OPKA 3NHNA 3VRNA 1A08A 3OV1A 1O48A 1G83A 4F5AA 1BLJA 1CWEA 1GRIA 2CI9A 1CSYA 1RJAA 5EEQA 2CBLA 1O4JA 2PLEA 1A1BA 4F5BA 1LUMA 2IZVA 3PSJA 1O4EA 2LNWA 3BKBA 1Z3KA 1KA6A 2LNXA 1RPYA 1R1SA 3BUWB 3QWYA 3N84A 1NZLA 3N8MA 1NZVA 2C0IA 1FBVA 1D4WA 1OO3A 3MXYA 2L3TA 3HIZB 3PLFB 5HKYA 2ETZA 4EY0A 2H46E 4LUEA 1TCEA 2HDXA 4P9ZA 1FU5A 3K2MA 3VS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LKK A;  1R1P A;  2DCR A;  2L6K A;  4XZ0 A;  4A4B A;  1SKJ A;  1R1Q A;  5DC9 A;  3S8N A;  3WA4 A;  1A09 A;  1BM2 A;  3TKZ A;  3VGO A;  2MRK A;  3OVE A;  3BUM B;  1FMK A;  3HCK A;  2MK2 A;  1LKL A;  5GJH A;  3OB1 B;  5IBM A;  2B3O A;  2GE9 A;  3IN7 A;  5I6V A;  2EYY A;  2PNB A;  1FBZ A;  5HKZ A;  1JWO A;  3QWX X;  4K11 A;  5HKW A;  4FL2 A;  2EO3 A;  1NRV A;  2L4K A;  2PTK A;  1H9O A;  4EIH A;  1LCJ A;  4FL3 A;  4U17 A;  1BF5 A;  2PNA A;  4E68 A;  3UF4 A;  2VIF A;  1QG1 E;  2YSX A;  4K45 A;  1AYC A;  5EHR A;  2FO0 A;  3IMD A;  2KNO A;  3VRP A;  2LQW A;  2IUI A;  5AUL A;  1O42 A;  1O45 A;  1SPR A;  1A81 A;  2GSB A;  3VS4 A;  1HCS B;  2IUH A;  4OHI A;  1JYU A;  3KFJ A;  5EEL A;  1O4K A;  4E93 A;  1LCK A;  1Y1U A;  2CI8 A;  1X27 A;  2ABL A;  4LUD A;  1O47 A;  1CJ1 A;  4A4C A;  1O4F A;  2EL8 A;  1TZE E;  2LQN A;  1BFJ A;  1O4M A;  2OQ1 A;  3N7Y A;  3PQZ A;  3VS7 A;  5DC4 A;  2Y1N A;  3UYO A;  2CRH A;  1A1E A;  5DC0 B;  4DGP A;  1O4H A;  3MAZ A;  4H34 A;  1B47 A;  4F59 A;  2OZO A;  2XP1 A;  1SPS A;  2SHP A;  2CIA A;  2EU0 A;  5J3X A;  3VRR A;  1O44 A;  2EOB A;  4XZ1 A;  1YVH A;  1JYR A;  1BMB A;  1SHD A;  1IJR A;  4U1P A;  2MC1 A;  1AOU F;  1O4B A;  2HMH A;  2BBU A;  2QMS A;  1O43 A;  2MRJ A;  2K79 B;  2C0T A;  2ECD A;  1KSW A;  4P9V A;  4JEG A;  1X6C A;  1BKM A;  4D8K A;  3S9K A;  1XA6 A;  4TZI A;  2PLD A;  4X6S A;  1D4T A;  4H1O A;  1D1Z A;  1LUI A;  4GWF A;  3VS0 A;  2JYQ A;  1OPL A;  3PS5 A;  3US4 A;  1OO4 A;  2C0O A;  1MW4 A;  1M27 A;  2C9W A;  1AB2 A;  2IUG A;  4QSY A;  2Y3A B;  5EHP A;  1YVL A;  2AOB A;  3MXC A;  5EG3 B;  1SHB A;  3IMJ A;  2DLY A;  1F1W A;  3OB2 B;  1A1C A;  3PJP A;  2FCI A;  3VRO A;  1BHH B;  1RQQ C;  3S8O A;  2HDV A;  1BHH A;  3CWG A;  3S8L A;  1BHF A;  1QAD A;  5DF6 A;  3VRZ A;  2LCT A;  1O4R A;  2Y1M A;  3VRY A;  5KAZ A;  2AOA A;  2ROR A;  2RMX A;  3TL0 A;  1FYR A;  4K44 A;  2EKX A;  5GJI A;  1O4L A;  3EAC A;  2EYV A;  1SHA A;  4ROJ A;  2AUG A;  2MQI A;  1I3Z A;  3ZNI A;  3BUN B;  2RVF A;  1BKL A;  5BO4 A;  1AYB A;  4M4Z A;  2DM0 A;  1FU6 A;  4DGX A;  3OP0 A;  1O4N A;  3GXX A;  2RSY A;  1LUN A;  2DVJ A;  2H5K A;  3VRQ A;  3VS1 A;  1O46 A;  1O4P A;  3VS3 A;  3BUX B;  4OHD A;  1KA7 A;  3HHM B;  3VS2 A;  1AYA A;  1BLK A;  2YU7 A;  2HCK A;  4FBN A;  1O4I A;  1GHU A;  3EAZ A;  2SRC A;  3M7F A;  1QCF A;  2CS0 A;  1O4Q A;  4JE4 A;  1O4D A;  2K7A B;  3BUO B;  5D0J A;  1O41 A;  3CBL A;  3GQI B;  4OHH A;  5AXI A;  3T04 A;  2CR4 A;  1BG1 A;  4OHE A;  2HUW A;  1FHS A;  1UUS A;  1O4C A;  1Y57 A;  1A1A A;  1HCT B;  1UUR A;  4OHL A;  1JYQ A;  4NWF A;  5IBS A;  1KC2 A;  1CSZ A;  4GPL B;  1X0N A;  1IS0 A;  1O4A A;  3VS5 A;  3PFV A;  4L1B B;  3C7I A;  1M61 A;  2DLZ A;  3IN8 A;  2EO6 A;  1CWD L;  1F2F A;  1K9A A;  2H8H A;  2EYZ A;  1O49 A;  4WWQ A;  1AOT F;  1WQU A;  4K2R A;  1LUK A;  4NWG A;  1P13 A;  1MIL A;  3CXL A;  1BFI A;  4GL9 E;  3GXW A;  4JGH A;  2DX0 A;  1PIC A;  1ZFP E;  1AYD A;  2KK6 A;  1JU5 A;  1O4O A;  1O4G A;  1AD5 A;  5CDW A;  1A07 A;  3PSK A;  3CD3 A;  1OPK A;  3NHN A;  3VRN A;  1A08 A;  3OV1 A;  1O48 A;  1G83 A;  4F5A A;  1BLJ A;  1CWE A;  1GRI A;  2CI9 A;  1CSY A;  1RJA A;  5EEQ A;  2CBL A;  1O4J A;  2PLE A;  1A1B A;  4F5B A;  1LUM A;  2IZV A;  3PSJ A;  1O4E A;  2LNW A;  3BKB A;  1Z3K A;  1KA6 A;  2LNX A;  1RPY A;  1R1S A;  3BUW B;  3QWY A;  3N84 A;  1NZL A;  3N8M A;  1NZV A;  2C0I A;  1FBV A;  1D4W A;  1OO3 A;  3MXY A;  2L3T A;  3HIZ B;  3PLF B;  5HKY A;  2ETZ A;  4EY0 A;  2H46 E;  4LUE A;  1TCE A;  2HDX A;  4P9Z A;  1FU5 A;  3K2M A;  3VS6 A; 
#chains in the Genus database with same CATH topology
 1LKK A;  1R1P A;  2DCR A;  2L6K A;  4XZ0 A;  4A4B A;  1SKJ A;  1R1Q A;  5DC9 A;  3S8N A;  3WA4 A;  1A09 A;  1BM2 A;  3TKZ A;  3VGO A;  2MRK A;  3OVE A;  3BUM B;  1FMK A;  3HCK A;  2MK2 A;  1LKL A;  5GJH A;  3OB1 B;  5IBM A;  2B3O A;  2GE9 A;  3IN7 A;  5I6V A;  2EYY A;  2PNB A;  1FBZ A;  5HKZ A;  1JWO A;  3QWX X;  4K11 A;  5HKW A;  4FL2 A;  2EO3 A;  1NRV A;  2L4K A;  2PTK A;  1H9O A;  4EIH A;  1LCJ A;  4FL3 A;  4U17 A;  1BF5 A;  2KGY A;  2PNA A;  4E68 A;  3UF4 A;  2VIF A;  1QG1 E;  2YSX A;  4K45 A;  1AYC A;  5EHR A;  2FO0 A;  3IMD A;  2KNO A;  3VRP A;  2LQW A;  2IUI A;  5AUL A;  1O42 A;  1O45 A;  1SPR A;  1A81 A;  2GSB A;  3VS4 A;  1HCS B;  2IUH A;  4OHI A;  1JYU A;  3KFJ A;  5EEL A;  1O4K A;  4E93 A;  1LCK A;  1Y1U A;  2CI8 A;  1X27 A;  2ABL A;  4LUD A;  1O47 A;  1CJ1 A;  4A4C A;  1O4F A;  2EL8 A;  1TZE E;  2LQN A;  1BFJ A;  1O4M A;  2OQ1 A;  3N7Y A;  3PQZ A;  3VS7 A;  5DC4 A;  2Y1N A;  3UYO A;  2CRH A;  1A1E A;  5DC0 B;  4DGP A;  1O4H A;  3MAZ A;  4H34 A;  1B47 A;  4F59 A;  2OZO A;  2XP1 A;  1SPS A;  2SHP A;  2CIA A;  2EU0 A;  5J3X A;  3VRR A;  1O44 A;  2EOB A;  4XZ1 A;  1YVH A;  1JYR A;  1BMB A;  1SHD A;  1IJR A;  4U1P A;  2MC1 A;  1AOU F;  1O4B A;  2HMH A;  2BBU A;  2QMS A;  1O43 A;  2MRJ A;  2K79 B;  2C0T A;  2ECD A;  1KSW A;  4P9V A;  4JEG A;  1X6C A;  1BKM A;  4D8K A;  3S9K A;  1XA6 A;  4TZI A;  2PLD A;  4X6S A;  1D4T A;  4H1O A;  1D1Z A;  1LUI A;  4GWF A;  3VS0 A;  2JYQ A;  1OPL A;  3PS5 A;  3US4 A;  1OO4 A;  2C0O A;  1MW4 A;  1M27 A;  2C9W A;  1AB2 A;  2IUG A;  4QSY A;  2Y3A B;  5EHP A;  1YVL A;  2AOB A;  3K2T A;  3MXC A;  5EG3 B;  1SHB A;  3IMJ A;  2DLY A;  1F1W A;  3OB2 B;  1A1C A;  3PJP A;  2FCI A;  3VRO A;  1BHH B;  1RQQ C;  3S8O A;  2HDV A;  1BHH A;  3CWG A;  3S8L A;  1BHF A;  1QAD A;  5DF6 A;  3VRZ A;  2LCT A;  1O4R A;  2Y1M A;  3VRY A;  5KAZ A;  2AOA A;  2ROR A;  2RMX A;  3TL0 A;  1FYR A;  4K44 A;  2EKX A;  5GJI A;  1O4L A;  3EAC A;  2EYV A;  1SHA A;  4ROJ A;  2AUG A;  2MQI A;  1I3Z A;  3ZNI A;  3BUN B;  2RVF A;  1BKL A;  5BO4 A;  1AYB A;  4M4Z A;  3LYV A;  2DM0 A;  1FU6 A;  4DGX A;  3OP0 A;  1O4N A;  3GXX A;  2RSY A;  1LUN A;  2DVJ A;  2H5K A;  3VRQ A;  3VS1 A;  1O46 A;  1O4P A;  3VS3 A;  3BUX B;  4OHD A;  1KA7 A;  3HHM B;  3VS2 A;  1AYA A;  1BLK A;  2YU7 A;  2HCK A;  4FBN A;  1O4I A;  1GHU A;  3EAZ A;  2SRC A;  3M7F A;  1QCF A;  2CS0 A;  1O4Q A;  4JE4 A;  1O4D A;  2K7A B;  3BUO B;  5D0J A;  1O41 A;  3CBL A;  3GQI B;  4OHH A;  5AXI A;  3T04 A;  2CR4 A;  1BG1 A;  4OHE A;  2HUW A;  1FHS A;  1UUS A;  1O4C A;  1Y57 A;  1A1A A;  1HCT B;  1UUR A;  4OHL A;  1JYQ A;  4NWF A;  5IBS A;  1KC2 A;  1CSZ A;  4GPL B;  1X0N A;  1IS0 A;  1O4A A;  3VS5 A;  3PFV A;  4L1B B;  3C7I A;  1M61 A;  2DLZ A;  2LRA A;  3IN8 A;  2EO6 A;  1CWD L;  1F2F A;  1K9A A;  2H8H A;  2EYZ A;  1O49 A;  4WWQ A;  1AOT F;  1WQU A;  4K2R A;  1LUK A;  4NWG A;  1P13 A;  1MIL A;  3CXL A;  1BFI A;  4GL9 E;  3GXW A;  4JGH A;  2DX0 A;  1PIC A;  1ZFP E;  1AYD A;  2KK6 A;  1JU5 A;  1O4O A;  1O4G A;  1AD5 A;  5CDW A;  1A07 A;  3PSK A;  3CD3 A;  1OPK A;  3NHN A;  3VRN A;  1A08 A;  3OV1 A;  1O48 A;  1G83 A;  4F5A A;  1BLJ A;  1CWE A;  1GRI A;  2CI9 A;  1CSY A;  1RJA A;  5EEQ A;  2CBL A;  1O4J A;  2PLE A;  1A1B A;  4F5B A;  1LUM A;  2IZV A;  3PSJ A;  1O4E A;  2LNW A;  3BKB A;  1Z3K A;  1KA6 A;  2LNX A;  1RPY A;  1R1S A;  3BUW B;  3QWY A;  3N84 A;  1NZL A;  3N8M A;  1NZV A;  2C0I A;  1FBV A;  1D4W A;  1OO3 A;  3MXY A;  2L3T A;  3HIZ B;  3PLF B;  5HKY A;  2ETZ A;  4EY0 A;  2H46 E;  4LUE A;  1TCE A;  2HDX A;  4P9Z A;  1FU5 A;  3K2M A;  3VS6 A; 
#chains in the Genus database with same CATH homology
 1LKK A;  1R1P A;  2DCR A;  2L6K A;  4XZ0 A;  4A4B A;  1SKJ A;  1R1Q A;  5DC9 A;  3S8N A;  3WA4 A;  1A09 A;  1BM2 A;  3TKZ A;  3VGO A;  2MRK A;  3OVE A;  3BUM B;  1FMK A;  3HCK A;  2MK2 A;  1LKL A;  5GJH A;  3OB1 B;  5IBM A;  2B3O A;  2GE9 A;  3IN7 A;  5I6V A;  2EYY A;  2PNB A;  1FBZ A;  5HKZ A;  1JWO A;  3QWX X;  4K11 A;  5HKW A;  4FL2 A;  2EO3 A;  1NRV A;  2L4K A;  2PTK A;  1H9O A;  4EIH A;  1LCJ A;  4FL3 A;  4U17 A;  1BF5 A;  2PNA A;  4E68 A;  3UF4 A;  2VIF A;  1QG1 E;  2YSX A;  4K45 A;  1AYC A;  5EHR A;  2FO0 A;  3IMD A;  2KNO A;  3VRP A;  2LQW A;  2IUI A;  5AUL A;  1O42 A;  1O45 A;  1SPR A;  1A81 A;  2GSB A;  3VS4 A;  1HCS B;  2IUH A;  4OHI A;  1JYU A;  3KFJ A;  5EEL A;  1O4K A;  4E93 A;  1LCK A;  1Y1U A;  2CI8 A;  1X27 A;  2ABL A;  4LUD A;  1O47 A;  1CJ1 A;  4A4C A;  1O4F A;  2EL8 A;  1TZE E;  2LQN A;  1BFJ A;  1O4M A;  2OQ1 A;  3N7Y A;  3PQZ A;  3VS7 A;  5DC4 A;  2Y1N A;  3UYO A;  2CRH A;  1A1E A;  5DC0 B;  4DGP A;  1O4H A;  3MAZ A;  4H34 A;  1B47 A;  4F59 A;  2OZO A;  2XP1 A;  1SPS A;  2SHP A;  2CIA A;  2EU0 A;  5J3X A;  3VRR A;  1O44 A;  2EOB A;  4XZ1 A;  1YVH A;  1JYR A;  1BMB A;  1SHD A;  1IJR A;  4U1P A;  2MC1 A;  1AOU F;  1O4B A;  2HMH A;  2BBU A;  2QMS A;  1O43 A;  2MRJ A;  2K79 B;  2C0T A;  2ECD A;  1KSW A;  4P9V A;  4JEG A;  1X6C A;  1BKM A;  4D8K A;  3S9K A;  1XA6 A;  4TZI A;  2PLD A;  4X6S A;  1D4T A;  4H1O A;  1D1Z A;  1LUI A;  4GWF A;  3VS0 A;  2JYQ A;  1OPL A;  3PS5 A;  3US4 A;  1OO4 A;  2C0O A;  1MW4 A;  1M27 A;  2C9W A;  1AB2 A;  2IUG A;  4QSY A;  2Y3A B;  5EHP A;  1YVL A;  2AOB A;  3MXC A;  5EG3 B;  1SHB A;  3IMJ A;  2DLY A;  1F1W A;  3OB2 B;  1A1C A;  3PJP A;  2FCI A;  3VRO A;  1BHH B;  1RQQ C;  3S8O A;  2HDV A;  1BHH A;  3CWG A;  3S8L A;  1BHF A;  1QAD A;  5DF6 A;  3VRZ A;  2LCT A;  1O4R A;  2Y1M A;  3VRY A;  5KAZ A;  2AOA A;  2ROR A;  2RMX A;  3TL0 A;  1FYR A;  4K44 A;  2EKX A;  5GJI A;  1O4L A;  3EAC A;  2EYV A;  1SHA A;  4ROJ A;  2AUG A;  2MQI A;  1I3Z A;  3ZNI A;  3BUN B;  2RVF A;  1BKL A;  5BO4 A;  1AYB A;  4M4Z A;  2DM0 A;  1FU6 A;  4DGX A;  3OP0 A;  1O4N A;  3GXX A;  2RSY A;  1LUN A;  2DVJ A;  2H5K A;  3VRQ A;  3VS1 A;  1O46 A;  1O4P A;  3VS3 A;  3BUX B;  4OHD A;  1KA7 A;  3HHM B;  3VS2 A;  1AYA A;  1BLK A;  2YU7 A;  2HCK A;  4FBN A;  1O4I A;  1GHU A;  3EAZ A;  2SRC A;  3M7F A;  1QCF A;  2CS0 A;  1O4Q A;  4JE4 A;  1O4D A;  2K7A B;  3BUO B;  5D0J A;  1O41 A;  3CBL A;  3GQI B;  4OHH A;  5AXI A;  3T04 A;  2CR4 A;  1BG1 A;  4OHE A;  2HUW A;  1FHS A;  1UUS A;  1O4C A;  1Y57 A;  1A1A A;  1HCT B;  1UUR A;  4OHL A;  1JYQ A;  4NWF A;  5IBS A;  1KC2 A;  1CSZ A;  4GPL B;  1X0N A;  1IS0 A;  1O4A A;  3VS5 A;  3PFV A;  4L1B B;  3C7I A;  1M61 A;  2DLZ A;  3IN8 A;  2EO6 A;  1CWD L;  1F2F A;  1K9A A;  2H8H A;  2EYZ A;  1O49 A;  4WWQ A;  1AOT F;  1WQU A;  4K2R A;  1LUK A;  4NWG A;  1P13 A;  1MIL A;  3CXL A;  1BFI A;  4GL9 E;  3GXW A;  4JGH A;  2DX0 A;  1PIC A;  1ZFP E;  1AYD A;  2KK6 A;  1JU5 A;  1O4O A;  1O4G A;  1AD5 A;  5CDW A;  1A07 A;  3PSK A;  3CD3 A;  1OPK A;  3NHN A;  3VRN A;  1A08 A;  3OV1 A;  1O48 A;  1G83 A;  4F5A A;  1BLJ A;  1CWE A;  1GRI A;  2CI9 A;  1CSY A;  1RJA A;  5EEQ A;  2CBL A;  1O4J A;  2PLE A;  1A1B A;  4F5B A;  1LUM A;  2IZV A;  3PSJ A;  1O4E A;  2LNW A;  3BKB A;  1Z3K A;  1KA6 A;  2LNX A;  1RPY A;  1R1S A;  3BUW B;  3QWY A;  3N84 A;  1NZL A;  3N8M A;  1NZV A;  2C0I A;  1FBV A;  1D4W A;  1OO3 A;  3MXY A;  2L3T A;  3HIZ B;  3PLF B;  5HKY A;  2ETZ A;  4EY0 A;  2H46 E;  4LUE A;  1TCE A;  2HDX A;  4P9Z A;  1FU5 A;  3K2M A;  3VS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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