1O4LA

Crystal structure of sh2 in complex with fragment2.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4lA00
4XZ0A 1ZFPE 1BG1A 2C9WA 1QCFA 2PLDA 4OHIA 4X6SA 2EOBA 2KNOA 1O47A 2PNAA 5BO4A 1FU6A 4F5AA 4ROJA 1O45A 5GJIA 4D8KA 2GE9A 2HCKA 2QMSA 1UURA 3CD3A 5IBMA 4OHEA 1KSWA 3PSJA 5D0JA 2EO3A 2EYZA 4GL9E 1JWOA 1O4QA 1X6CA 3TKZA 1SHAA 2YSXA 1Y1UA 1O4JA 1TZEE 4A4CA 5GJHA 1O49A 1O4PA 2K7AB 2IUGA 1O4KA 2H8HA 1QADA 1O4DA 4U17A 1O42A 3T04A 4L1BB 1O4NA 4GPLB 4XZ1A 1FHSA 3BUWB 2YU7A 1BLJA 2LNWA 3OP0A 4K11A 1HCSB 2XP1A 1G83A 1O4HA 3S8OA 5EEQA 5DC0B 5DC4A 1CWEA 1A09A 2RMXA 3IMJA 5EHRA 3VRRA 2L3TA 3BUNB 3GXWA 2VIFA 4H34A 4OHDA 1NZLA 2AOBA 4P9ZA 5HKYA 1D4WA 3OB1B 3PSKA 2SHPA 1R1SA 1BLKA 2DLZA 2AUGA 2B3OA 1NRVA 4K44A 1RJAA 3KFJA 1KA7A 1X27A 2H5KA 1HCTB 3VS2A 3VRYA 4JE4A 1BM2A 3M7FA 3PFVA 1A81A 1OPLA 1M61A 2DM0A 3IN8A 3VROA 1SKJA 2CI8A 1BMBA 1O4FA 1R1QA 2EYYA 2LCTA 1NZVA 1BF5A 1X0NA 3QWYA 1O4OA 4JEGA 3S8LA 2DCRA 2SRCA 3IMDA 1LUMA 1JU5A 2C0TA 2EKXA 5HKZA 1O48A 2C0IA 1AYDA 3BUXB 1LUNA 2OZOA 3VS0A 2EU0A 2PLEA 3MXYA 3WA4A 4WWQA 2DVJA 4TZIA 1CSZA 1A08A 3MXCA 4K2RA 1CJ1A 3PS5A 4M4ZA 2DLYA 1M27A 5AXIA 3VS1A 1F2FA 1YVHA 1KC2A 1O4RA 1XA6A 3N84A 1O4IA 3OB2B 3BKBA 1JYUA 1CWDL 1BHHA 4H1OA 4LUDA 3NHNA 1A1CA 1LKKA 1O4BA 2PNBA 1O44A 1RQQC 5EG3B 1SHBA 3VS3A 1O4GA 3CBLA 2EYVA 3K2MA 3MAZA 5AULA 2DX0A 1QG1E 5HKWA 2HDVA 1O46A 2FCIA 2EL8A 2MK2A 3TL0A 1O4MA 5EHPA 3VS6A 1D1ZA 1I3ZA 1D4TA 1FYRA 3PQZA 3VRPA 1A1EA 1WQUA 2ETZA 4DGPA 1O4LA 1FBZA 4U1PA 1CSYA 2Y1MA 3HIZB 1O4CA 3N8MA 2KK6A 1KA6A 3S9KA 3N7YA 3VRZA 4FL2A 2RVFA 1UUSA 1FBVA 1AYCA 1GHUA 1GRIA 1K9AA 3BUOB 2MQIA 5DF6A 2CBLA 2IZVA 1LCKA 3CWGA 1OPKA 1FMKA 1R1PA 1AYBA 1A1AA 4OHLA 5IBSA 1JYQA 1PICA 1OO3A 4OHHA 3OV1A 2CR4A 2Y3AB 2OQ1A 1H9OA 4FBNA 2AOAA 2MC1A 3VRQA 1O41A 2MRJA 1F1WA 4FL3A 2IUHA 3PJPA 2CI9A 2HMHA 2RSYA 1AOTF 2L4KA 4NWFA 3HHMB 2LQWA 3GXXA 2HDXA 5EELA 4EY0A 2RORA 2L6KA 3C7IA 5DC9A 4JGHA 1MW4A 4DGXA 1SPRA 2BBUA 1AD5A 2ABLA 1BKMA 4GWFA 1OO4A 1Z3KA 3GQIB 4E93A 4EIHA 1RPYA 3BUMB 1Y57A 2Y1NA 1AYAA 4QSYA 5J3XA 4F59A 1SHDA 1JYRA 5KAZA 1BHHB 2ECDA 2GSBA 4E68A 2PTKA 2FO0A 4A4BA 2CS0A 1IJRA 2EO6A 3US4A 1LCJA 3UYOA 4NWGA 1P13A 2MRKA 1SPSA 3IN7A 3VRNA 1A07A 2CRHA 3ZNIA 2LQNA 2CIAA 1LUIA 2H46E 3PLFB 3HCKA 1BFIA 3EACA 1A1BA 3VS7A 1FU5A 3UF4A 5CDWA 1O43A 1LUKA 3VS4A 5I6VA 4LUEA 1BKLA 2IUIA 1O4AA 1YVLA 1MILA 3QWXX 1B47A 3OVEA 2JYQA 1O4EA 1LKLA 1IS0A 1AOUF 2C0OA 2HUWA 4F5BA 1BFJA 3S8NA 3CXLA 3VGOA 4K45A 2K79B 1AB2A 1BHFA 4P9VA 2LNXA 1TCEA 3VS5A 3EAZA
chains in the Genus database with same CATH superfamily
4XZ0A 1ZFPE 1BG1A 2C9WA 1QCFA 2PLDA 4OHIA 4X6SA 2EOBA 2KNOA 1O47A 2PNAA 5BO4A 1FU6A 2LRAA 4F5AA 4ROJA 1O45A 5GJIA 4D8KA 2GE9A 2HCKA 2QMSA 1UURA 3CD3A 5IBMA 4OHEA 1KSWA 3PSJA 2KGYA 5D0JA 2EO3A 2EYZA 4GL9E 1JWOA 1O4QA 1X6CA 3TKZA 1SHAA 2YSXA 1Y1UA 1O4JA 1TZEE 4A4CA 5GJHA 1O49A 1O4PA 2K7AB 2IUGA 1O4KA 2H8HA 1QADA 1O4DA 4U17A 1O42A 3T04A 4L1BB 1O4NA 4GPLB 4XZ1A 1FHSA 3BUWB 2YU7A 1BLJA 2LNWA 3OP0A 4K11A 1HCSB 2XP1A 1G83A 1O4HA 3S8OA 5EEQA 5DC0B 5DC4A 1CWEA 1A09A 2RMXA 3IMJA 5EHRA 3VRRA 2L3TA 3BUNB 3GXWA 2VIFA 4H34A 4OHDA 1NZLA 2AOBA 4P9ZA 5HKYA 1D4WA 3OB1B 3PSKA 2SHPA 1R1SA 1BLKA 2DLZA 2AUGA 2B3OA 1NRVA 4K44A 1RJAA 3KFJA 1KA7A 1X27A 2H5KA 1HCTB 3VS2A 3VRYA 4JE4A 1BM2A 3M7FA 3PFVA 1A81A 1OPLA 1M61A 2DM0A 3IN8A 3VROA 1SKJA 2CI8A 3LYVA 1BMBA 1O4FA 1R1QA 2EYYA 2LCTA 1NZVA 1BF5A 1X0NA 3QWYA 1O4OA 4JEGA 3S8LA 2DCRA 2SRCA 3IMDA 1LUMA 1JU5A 2C0TA 2EKXA 5HKZA 1O48A 2C0IA 1AYDA 3BUXB 1LUNA 2OZOA 3VS0A 2EU0A 2PLEA 3MXYA 3WA4A 4WWQA 2DVJA 4TZIA 1CSZA 1A08A 3MXCA 4K2RA 1CJ1A 3PS5A 4M4ZA 2DLYA 1M27A 5AXIA 3VS1A 1F2FA 1YVHA 1KC2A 1O4RA 1XA6A 3N84A 1O4IA 3OB2B 3BKBA 1JYUA 1CWDL 1BHHA 4H1OA 4LUDA 3NHNA 1A1CA 1LKKA 1O4BA 2PNBA 1O44A 1RQQC 5EG3B 1SHBA 3VS3A 1O4GA 3CBLA 2EYVA 3K2MA 3MAZA 5AULA 2DX0A 3K2TA 1QG1E 5HKWA 2HDVA 1O46A 2FCIA 2EL8A 2MK2A 3TL0A 1O4MA 5EHPA 3VS6A 1D1ZA 1I3ZA 1D4TA 1FYRA 3PQZA 3VRPA 1A1EA 1WQUA 2ETZA 4DGPA 1O4LA 1FBZA 4U1PA 1CSYA 2Y1MA 3HIZB 1O4CA 3N8MA 2KK6A 1KA6A 3S9KA 3N7YA 3VRZA 4FL2A 2RVFA 1UUSA 1FBVA 1AYCA 1GHUA 1GRIA 1K9AA 3BUOB 2MQIA 5DF6A 2CBLA 2IZVA 1LCKA 3CWGA 1OPKA 1FMKA 1R1PA 1AYBA 1A1AA 4OHLA 5IBSA 1JYQA 1PICA 1OO3A 4OHHA 3OV1A 2CR4A 2Y3AB 2OQ1A 1H9OA 4FBNA 2AOAA 2MC1A 3VRQA 1O41A 2MRJA 1F1WA 4FL3A 2IUHA 3PJPA 2CI9A 2HMHA 2RSYA 1AOTF 2L4KA 4NWFA 3HHMB 2LQWA 3GXXA 2HDXA 5EELA 4EY0A 2RORA 2L6KA 3C7IA 5DC9A 4JGHA 1MW4A 4DGXA 1SPRA 2BBUA 1AD5A 2ABLA 1BKMA 4GWFA 1OO4A 1Z3KA 3GQIB 4E93A 4EIHA 1RPYA 3BUMB 1Y57A 2Y1NA 1AYAA 4QSYA 5J3XA 4F59A 1SHDA 1JYRA 5KAZA 1BHHB 2ECDA 2GSBA 4E68A 2PTKA 2FO0A 4A4BA 2CS0A 1IJRA 2EO6A 3US4A 1LCJA 3UYOA 4NWGA 1P13A 2MRKA 1SPSA 3IN7A 3VRNA 1A07A 2CRHA 3ZNIA 2LQNA 2CIAA 1LUIA 2H46E 3PLFB 3HCKA 1BFIA 3EACA 1A1BA 3VS7A 1FU5A 3UF4A 5CDWA 1O43A 1LUKA 3VS4A 5I6VA 4LUEA 1BKLA 2IUIA 1O4AA 1YVLA 1MILA 3QWXX 1B47A 3OVEA 2JYQA 1O4EA 1LKLA 1IS0A 1AOUF 2C0OA 2HUWA 4F5BA 1BFJA 3S8NA 3CXLA 3VGOA 4K45A 2K79B 1AB2A 1BHFA 4P9VA 2LNXA 1TCEA 3VS5A 3EAZA
chains in the Genus database with same CATH topology
4XZ0A 1ZFPE 1BG1A 2C9WA 1QCFA 2PLDA 4OHIA 4X6SA 2EOBA 2KNOA 1O47A 2PNAA 5BO4A 1FU6A 4F5AA 4ROJA 1O45A 5GJIA 4D8KA 2GE9A 2HCKA 2QMSA 1UURA 3CD3A 5IBMA 4OHEA 1KSWA 3PSJA 5D0JA 2EO3A 2EYZA 4GL9E 1JWOA 1O4QA 1X6CA 3TKZA 1SHAA 2YSXA 1Y1UA 1O4JA 1TZEE 4A4CA 5GJHA 1O49A 1O4PA 2K7AB 2IUGA 1O4KA 2H8HA 1QADA 1O4DA 4U17A 1O42A 3T04A 4L1BB 1O4NA 4GPLB 4XZ1A 1FHSA 3BUWB 2YU7A 1BLJA 2LNWA 3OP0A 4K11A 1HCSB 2XP1A 1G83A 1O4HA 3S8OA 5EEQA 5DC0B 5DC4A 1CWEA 1A09A 2RMXA 3IMJA 5EHRA 3VRRA 2L3TA 3BUNB 3GXWA 2VIFA 4H34A 4OHDA 1NZLA 2AOBA 4P9ZA 5HKYA 1D4WA 3OB1B 3PSKA 2SHPA 1R1SA 1BLKA 2DLZA 2AUGA 2B3OA 1NRVA 4K44A 1RJAA 3KFJA 1KA7A 1X27A 2H5KA 1HCTB 3VS2A 3VRYA 4JE4A 1BM2A 3M7FA 3PFVA 1A81A 1OPLA 1M61A 2DM0A 3IN8A 3VROA 1SKJA 2CI8A 1BMBA 1O4FA 1R1QA 2EYYA 2LCTA 1NZVA 1BF5A 1X0NA 3QWYA 1O4OA 4JEGA 3S8LA 2DCRA 2SRCA 3IMDA 1LUMA 1JU5A 2C0TA 2EKXA 5HKZA 1O48A 2C0IA 1AYDA 3BUXB 1LUNA 2OZOA 3VS0A 2EU0A 2PLEA 3MXYA 3WA4A 4WWQA 2DVJA 4TZIA 1CSZA 1A08A 3MXCA 4K2RA 1CJ1A 3PS5A 4M4ZA 2DLYA 1M27A 5AXIA 3VS1A 1F2FA 1YVHA 1KC2A 1O4RA 1XA6A 3N84A 1O4IA 3OB2B 3BKBA 1JYUA 1CWDL 1BHHA 4H1OA 4LUDA 3NHNA 1A1CA 1LKKA 1O4BA 2PNBA 1O44A 1RQQC 5EG3B 1SHBA 3VS3A 1O4GA 3CBLA 2EYVA 3K2MA 3MAZA 5AULA 2DX0A 1QG1E 5HKWA 2HDVA 1O46A 2FCIA 2EL8A 2MK2A 3TL0A 1O4MA 5EHPA 3VS6A 1D1ZA 1I3ZA 1D4TA 1FYRA 3PQZA 3VRPA 1A1EA 1WQUA 2ETZA 4DGPA 1O4LA 1FBZA 4U1PA 1CSYA 2Y1MA 3HIZB 1O4CA 3N8MA 2KK6A 1KA6A 3S9KA 3N7YA 3VRZA 4FL2A 2RVFA 1UUSA 1FBVA 1AYCA 1GHUA 1GRIA 1K9AA 3BUOB 2MQIA 5DF6A 2CBLA 2IZVA 1LCKA 3CWGA 1OPKA 1FMKA 1R1PA 1AYBA 1A1AA 4OHLA 5IBSA 1JYQA 1PICA 1OO3A 4OHHA 3OV1A 2CR4A 2Y3AB 2OQ1A 1H9OA 4FBNA 2AOAA 2MC1A 3VRQA 1O41A 2MRJA 1F1WA 4FL3A 2IUHA 3PJPA 2CI9A 2HMHA 2RSYA 1AOTF 2L4KA 4NWFA 3HHMB 2LQWA 3GXXA 2HDXA 5EELA 4EY0A 2RORA 2L6KA 3C7IA 5DC9A 4JGHA 1MW4A 4DGXA 1SPRA 2BBUA 1AD5A 2ABLA 1BKMA 4GWFA 1OO4A 1Z3KA 3GQIB 4E93A 4EIHA 1RPYA 3BUMB 1Y57A 2Y1NA 1AYAA 4QSYA 5J3XA 4F59A 1SHDA 1JYRA 5KAZA 1BHHB 2ECDA 2GSBA 4E68A 2PTKA 2FO0A 4A4BA 2CS0A 1IJRA 2EO6A 3US4A 1LCJA 3UYOA 4NWGA 1P13A 2MRKA 1SPSA 3IN7A 3VRNA 1A07A 2CRHA 3ZNIA 2LQNA 2CIAA 1LUIA 2H46E 3PLFB 3HCKA 1BFIA 3EACA 1A1BA 3VS7A 1FU5A 3UF4A 5CDWA 1O43A 1LUKA 3VS4A 5I6VA 4LUEA 1BKLA 2IUIA 1O4AA 1YVLA 1MILA 3QWXX 1B47A 3OVEA 2JYQA 1O4EA 1LKLA 1IS0A 1AOUF 2C0OA 2HUWA 4F5BA 1BFJA 3S8NA 3CXLA 3VGOA 4K45A 2K79B 1AB2A 1BHFA 4P9VA 2LNXA 1TCEA 3VS5A 3EAZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XZ0 A;  1ZFP E;  1BG1 A;  2C9W A;  1QCF A;  2PLD A;  4OHI A;  4X6S A;  2EOB A;  2KNO A;  1O47 A;  2PNA A;  5BO4 A;  1FU6 A;  4F5A A;  4ROJ A;  1O45 A;  5GJI A;  4D8K A;  2GE9 A;  2HCK A;  2QMS A;  1UUR A;  3CD3 A;  5IBM A;  4OHE A;  1KSW A;  3PSJ A;  5D0J A;  2EO3 A;  2EYZ A;  4GL9 E;  1JWO A;  1O4Q A;  1X6C A;  3TKZ A;  1SHA A;  2YSX A;  1Y1U A;  1O4J A;  1TZE E;  4A4C A;  5GJH A;  1O49 A;  1O4P A;  2K7A B;  2IUG A;  1O4K A;  2H8H A;  1QAD A;  1O4D A;  4U17 A;  1O42 A;  3T04 A;  4L1B B;  1O4N A;  4GPL B;  4XZ1 A;  1FHS A;  3BUW B;  2YU7 A;  1BLJ A;  2LNW A;  3OP0 A;  4K11 A;  1HCS B;  2XP1 A;  1G83 A;  1O4H A;  3S8O A;  5EEQ A;  5DC0 B;  5DC4 A;  1CWE A;  1A09 A;  2RMX A;  3IMJ A;  5EHR A;  3VRR A;  2L3T A;  3BUN B;  3GXW A;  2VIF A;  4H34 A;  4OHD A;  1NZL A;  2AOB A;  4P9Z A;  5HKY A;  1D4W A;  3OB1 B;  3PSK A;  2SHP A;  1R1S A;  1BLK A;  2DLZ A;  2AUG A;  2B3O A;  1NRV A;  4K44 A;  1RJA A;  3KFJ A;  1KA7 A;  1X27 A;  2H5K A;  1HCT B;  3VS2 A;  3VRY A;  4JE4 A;  1BM2 A;  3M7F A;  3PFV A;  1A81 A;  1OPL A;  1M61 A;  2DM0 A;  3IN8 A;  3VRO A;  1SKJ A;  2CI8 A;  1BMB A;  1O4F A;  1R1Q A;  2EYY A;  2LCT A;  1NZV A;  1BF5 A;  1X0N A;  3QWY A;  1O4O A;  4JEG A;  3S8L A;  2DCR A;  2SRC A;  3IMD A;  1LUM A;  1JU5 A;  2C0T A;  2EKX A;  5HKZ A;  1O48 A;  2C0I A;  1AYD A;  3BUX B;  1LUN A;  2OZO A;  3VS0 A;  2EU0 A;  2PLE A;  3MXY A;  3WA4 A;  4WWQ A;  2DVJ A;  4TZI A;  1CSZ A;  1A08 A;  3MXC A;  4K2R A;  1CJ1 A;  3PS5 A;  4M4Z A;  2DLY A;  1M27 A;  5AXI A;  3VS1 A;  1F2F A;  1YVH A;  1KC2 A;  1O4R A;  1XA6 A;  3N84 A;  1O4I A;  3OB2 B;  3BKB A;  1JYU A;  1CWD L;  1BHH A;  4H1O A;  4LUD A;  3NHN A;  1A1C A;  1LKK A;  1O4B A;  2PNB A;  1O44 A;  1RQQ C;  5EG3 B;  1SHB A;  3VS3 A;  1O4G A;  3CBL A;  2EYV A;  3K2M A;  3MAZ A;  5AUL A;  2DX0 A;  1QG1 E;  5HKW A;  2HDV A;  1O46 A;  2FCI A;  2EL8 A;  2MK2 A;  3TL0 A;  1O4M A;  5EHP A;  3VS6 A;  1D1Z A;  1I3Z A;  1D4T A;  1FYR A;  3PQZ A;  3VRP A;  1A1E A;  1WQU A;  2ETZ A;  4DGP A;  1O4L A;  1FBZ A;  4U1P A;  1CSY A;  2Y1M A;  3HIZ B;  1O4C A;  3N8M A;  2KK6 A;  1KA6 A;  3S9K A;  3N7Y A;  3VRZ A;  4FL2 A;  2RVF A;  1UUS A;  1FBV A;  1AYC A;  1GHU A;  1GRI A;  1K9A A;  3BUO B;  2MQI A;  5DF6 A;  2CBL A;  2IZV A;  1LCK A;  3CWG A;  1OPK A;  1FMK A;  1R1P A;  1AYB A;  1A1A A;  4OHL A;  5IBS A;  1JYQ A;  1PIC A;  1OO3 A;  4OHH A;  3OV1 A;  2CR4 A;  2Y3A B;  2OQ1 A;  1H9O A;  4FBN A;  2AOA A;  2MC1 A;  3VRQ A;  1O41 A;  2MRJ A;  1F1W A;  4FL3 A;  2IUH A;  3PJP A;  2CI9 A;  2HMH A;  2RSY A;  1AOT F;  2L4K A;  4NWF A;  3HHM B;  2LQW A;  3GXX A;  2HDX A;  5EEL A;  4EY0 A;  2ROR A;  2L6K A;  3C7I A;  5DC9 A;  4JGH A;  1MW4 A;  4DGX A;  1SPR A;  2BBU A;  1AD5 A;  2ABL A;  1BKM A;  4GWF A;  1OO4 A;  1Z3K A;  3GQI B;  4E93 A;  4EIH A;  1RPY A;  3BUM B;  1Y57 A;  2Y1N A;  1AYA A;  4QSY A;  5J3X A;  4F59 A;  1SHD A;  1JYR A;  5KAZ A;  1BHH B;  2ECD A;  2GSB A;  4E68 A;  2PTK A;  2FO0 A;  4A4B A;  2CS0 A;  1IJR A;  2EO6 A;  3US4 A;  1LCJ A;  3UYO A;  4NWG A;  1P13 A;  2MRK A;  1SPS A;  3IN7 A;  3VRN A;  1A07 A;  2CRH A;  3ZNI A;  2LQN A;  2CIA A;  1LUI A;  2H46 E;  3PLF B;  3HCK A;  1BFI A;  3EAC A;  1A1B A;  3VS7 A;  1FU5 A;  3UF4 A;  5CDW A;  1O43 A;  1LUK A;  3VS4 A;  5I6V A;  4LUE A;  1BKL A;  2IUI A;  1O4A A;  1YVL A;  1MIL A;  3QWX X;  1B47 A;  3OVE A;  2JYQ A;  1O4E A;  1LKL A;  1IS0 A;  1AOU F;  2C0O A;  2HUW A;  4F5B A;  1BFJ A;  3S8N A;  3CXL A;  3VGO A;  4K45 A;  2K79 B;  1AB2 A;  1BHF A;  4P9V A;  2LNX A;  1TCE A;  3VS5 A;  3EAZ A; 
#chains in the Genus database with same CATH topology
 4XZ0 A;  1ZFP E;  1BG1 A;  2C9W A;  1QCF A;  2PLD A;  4OHI A;  4X6S A;  2EOB A;  2KNO A;  1O47 A;  2PNA A;  5BO4 A;  1FU6 A;  2LRA A;  4F5A A;  4ROJ A;  1O45 A;  5GJI A;  4D8K A;  2GE9 A;  2HCK A;  2QMS A;  1UUR A;  3CD3 A;  5IBM A;  4OHE A;  1KSW A;  3PSJ A;  2KGY A;  5D0J A;  2EO3 A;  2EYZ A;  4GL9 E;  1JWO A;  1O4Q A;  1X6C A;  3TKZ A;  1SHA A;  2YSX A;  1Y1U A;  1O4J A;  1TZE E;  4A4C A;  5GJH A;  1O49 A;  1O4P A;  2K7A B;  2IUG A;  1O4K A;  2H8H A;  1QAD A;  1O4D A;  4U17 A;  1O42 A;  3T04 A;  4L1B B;  1O4N A;  4GPL B;  4XZ1 A;  1FHS A;  3BUW B;  2YU7 A;  1BLJ A;  2LNW A;  3OP0 A;  4K11 A;  1HCS B;  2XP1 A;  1G83 A;  1O4H A;  3S8O A;  5EEQ A;  5DC0 B;  5DC4 A;  1CWE A;  1A09 A;  2RMX A;  3IMJ A;  5EHR A;  3VRR A;  2L3T A;  3BUN B;  3GXW A;  2VIF A;  4H34 A;  4OHD A;  1NZL A;  2AOB A;  4P9Z A;  5HKY A;  1D4W A;  3OB1 B;  3PSK A;  2SHP A;  1R1S A;  1BLK A;  2DLZ A;  2AUG A;  2B3O A;  1NRV A;  4K44 A;  1RJA A;  3KFJ A;  1KA7 A;  1X27 A;  2H5K A;  1HCT B;  3VS2 A;  3VRY A;  4JE4 A;  1BM2 A;  3M7F A;  3PFV A;  1A81 A;  1OPL A;  1M61 A;  2DM0 A;  3IN8 A;  3VRO A;  1SKJ A;  2CI8 A;  3LYV A;  1BMB A;  1O4F A;  1R1Q A;  2EYY A;  2LCT A;  1NZV A;  1BF5 A;  1X0N A;  3QWY A;  1O4O A;  4JEG A;  3S8L A;  2DCR A;  2SRC A;  3IMD A;  1LUM A;  1JU5 A;  2C0T A;  2EKX A;  5HKZ A;  1O48 A;  2C0I A;  1AYD A;  3BUX B;  1LUN A;  2OZO A;  3VS0 A;  2EU0 A;  2PLE A;  3MXY A;  3WA4 A;  4WWQ A;  2DVJ A;  4TZI A;  1CSZ A;  1A08 A;  3MXC A;  4K2R A;  1CJ1 A;  3PS5 A;  4M4Z A;  2DLY A;  1M27 A;  5AXI A;  3VS1 A;  1F2F A;  1YVH A;  1KC2 A;  1O4R A;  1XA6 A;  3N84 A;  1O4I A;  3OB2 B;  3BKB A;  1JYU A;  1CWD L;  1BHH A;  4H1O A;  4LUD A;  3NHN A;  1A1C A;  1LKK A;  1O4B A;  2PNB A;  1O44 A;  1RQQ C;  5EG3 B;  1SHB A;  3VS3 A;  1O4G A;  3CBL A;  2EYV A;  3K2M A;  3MAZ A;  5AUL A;  2DX0 A;  3K2T A;  1QG1 E;  5HKW A;  2HDV A;  1O46 A;  2FCI A;  2EL8 A;  2MK2 A;  3TL0 A;  1O4M A;  5EHP A;  3VS6 A;  1D1Z A;  1I3Z A;  1D4T A;  1FYR A;  3PQZ A;  3VRP A;  1A1E A;  1WQU A;  2ETZ A;  4DGP A;  1O4L A;  1FBZ A;  4U1P A;  1CSY A;  2Y1M A;  3HIZ B;  1O4C A;  3N8M A;  2KK6 A;  1KA6 A;  3S9K A;  3N7Y A;  3VRZ A;  4FL2 A;  2RVF A;  1UUS A;  1FBV A;  1AYC A;  1GHU A;  1GRI A;  1K9A A;  3BUO B;  2MQI A;  5DF6 A;  2CBL A;  2IZV A;  1LCK A;  3CWG A;  1OPK A;  1FMK A;  1R1P A;  1AYB A;  1A1A A;  4OHL A;  5IBS A;  1JYQ A;  1PIC A;  1OO3 A;  4OHH A;  3OV1 A;  2CR4 A;  2Y3A B;  2OQ1 A;  1H9O A;  4FBN A;  2AOA A;  2MC1 A;  3VRQ A;  1O41 A;  2MRJ A;  1F1W A;  4FL3 A;  2IUH A;  3PJP A;  2CI9 A;  2HMH A;  2RSY A;  1AOT F;  2L4K A;  4NWF A;  3HHM B;  2LQW A;  3GXX A;  2HDX A;  5EEL A;  4EY0 A;  2ROR A;  2L6K A;  3C7I A;  5DC9 A;  4JGH A;  1MW4 A;  4DGX A;  1SPR A;  2BBU A;  1AD5 A;  2ABL A;  1BKM A;  4GWF A;  1OO4 A;  1Z3K A;  3GQI B;  4E93 A;  4EIH A;  1RPY A;  3BUM B;  1Y57 A;  2Y1N A;  1AYA A;  4QSY A;  5J3X A;  4F59 A;  1SHD A;  1JYR A;  5KAZ A;  1BHH B;  2ECD A;  2GSB A;  4E68 A;  2PTK A;  2FO0 A;  4A4B A;  2CS0 A;  1IJR A;  2EO6 A;  3US4 A;  1LCJ A;  3UYO A;  4NWG A;  1P13 A;  2MRK A;  1SPS A;  3IN7 A;  3VRN A;  1A07 A;  2CRH A;  3ZNI A;  2LQN A;  2CIA A;  1LUI A;  2H46 E;  3PLF B;  3HCK A;  1BFI A;  3EAC A;  1A1B A;  3VS7 A;  1FU5 A;  3UF4 A;  5CDW A;  1O43 A;  1LUK A;  3VS4 A;  5I6V A;  4LUE A;  1BKL A;  2IUI A;  1O4A A;  1YVL A;  1MIL A;  3QWX X;  1B47 A;  3OVE A;  2JYQ A;  1O4E A;  1LKL A;  1IS0 A;  1AOU F;  2C0O A;  2HUW A;  4F5B A;  1BFJ A;  3S8N A;  3CXL A;  3VGO A;  4K45 A;  2K79 B;  1AB2 A;  1BHF A;  4P9V A;  2LNX A;  1TCE A;  3VS5 A;  3EAZ A; 
#chains in the Genus database with same CATH homology
 4XZ0 A;  1ZFP E;  1BG1 A;  2C9W A;  1QCF A;  2PLD A;  4OHI A;  4X6S A;  2EOB A;  2KNO A;  1O47 A;  2PNA A;  5BO4 A;  1FU6 A;  4F5A A;  4ROJ A;  1O45 A;  5GJI A;  4D8K A;  2GE9 A;  2HCK A;  2QMS A;  1UUR A;  3CD3 A;  5IBM A;  4OHE A;  1KSW A;  3PSJ A;  5D0J A;  2EO3 A;  2EYZ A;  4GL9 E;  1JWO A;  1O4Q A;  1X6C A;  3TKZ A;  1SHA A;  2YSX A;  1Y1U A;  1O4J A;  1TZE E;  4A4C A;  5GJH A;  1O49 A;  1O4P A;  2K7A B;  2IUG A;  1O4K A;  2H8H A;  1QAD A;  1O4D A;  4U17 A;  1O42 A;  3T04 A;  4L1B B;  1O4N A;  4GPL B;  4XZ1 A;  1FHS A;  3BUW B;  2YU7 A;  1BLJ A;  2LNW A;  3OP0 A;  4K11 A;  1HCS B;  2XP1 A;  1G83 A;  1O4H A;  3S8O A;  5EEQ A;  5DC0 B;  5DC4 A;  1CWE A;  1A09 A;  2RMX A;  3IMJ A;  5EHR A;  3VRR A;  2L3T A;  3BUN B;  3GXW A;  2VIF A;  4H34 A;  4OHD A;  1NZL A;  2AOB A;  4P9Z A;  5HKY A;  1D4W A;  3OB1 B;  3PSK A;  2SHP A;  1R1S A;  1BLK A;  2DLZ A;  2AUG A;  2B3O A;  1NRV A;  4K44 A;  1RJA A;  3KFJ A;  1KA7 A;  1X27 A;  2H5K A;  1HCT B;  3VS2 A;  3VRY A;  4JE4 A;  1BM2 A;  3M7F A;  3PFV A;  1A81 A;  1OPL A;  1M61 A;  2DM0 A;  3IN8 A;  3VRO A;  1SKJ A;  2CI8 A;  1BMB A;  1O4F A;  1R1Q A;  2EYY A;  2LCT A;  1NZV A;  1BF5 A;  1X0N A;  3QWY A;  1O4O A;  4JEG A;  3S8L A;  2DCR A;  2SRC A;  3IMD A;  1LUM A;  1JU5 A;  2C0T A;  2EKX A;  5HKZ A;  1O48 A;  2C0I A;  1AYD A;  3BUX B;  1LUN A;  2OZO A;  3VS0 A;  2EU0 A;  2PLE A;  3MXY A;  3WA4 A;  4WWQ A;  2DVJ A;  4TZI A;  1CSZ A;  1A08 A;  3MXC A;  4K2R A;  1CJ1 A;  3PS5 A;  4M4Z A;  2DLY A;  1M27 A;  5AXI A;  3VS1 A;  1F2F A;  1YVH A;  1KC2 A;  1O4R A;  1XA6 A;  3N84 A;  1O4I A;  3OB2 B;  3BKB A;  1JYU A;  1CWD L;  1BHH A;  4H1O A;  4LUD A;  3NHN A;  1A1C A;  1LKK A;  1O4B A;  2PNB A;  1O44 A;  1RQQ C;  5EG3 B;  1SHB A;  3VS3 A;  1O4G A;  3CBL A;  2EYV A;  3K2M A;  3MAZ A;  5AUL A;  2DX0 A;  1QG1 E;  5HKW A;  2HDV A;  1O46 A;  2FCI A;  2EL8 A;  2MK2 A;  3TL0 A;  1O4M A;  5EHP A;  3VS6 A;  1D1Z A;  1I3Z A;  1D4T A;  1FYR A;  3PQZ A;  3VRP A;  1A1E A;  1WQU A;  2ETZ A;  4DGP A;  1O4L A;  1FBZ A;  4U1P A;  1CSY A;  2Y1M A;  3HIZ B;  1O4C A;  3N8M A;  2KK6 A;  1KA6 A;  3S9K A;  3N7Y A;  3VRZ A;  4FL2 A;  2RVF A;  1UUS A;  1FBV A;  1AYC A;  1GHU A;  1GRI A;  1K9A A;  3BUO B;  2MQI A;  5DF6 A;  2CBL A;  2IZV A;  1LCK A;  3CWG A;  1OPK A;  1FMK A;  1R1P A;  1AYB A;  1A1A A;  4OHL A;  5IBS A;  1JYQ A;  1PIC A;  1OO3 A;  4OHH A;  3OV1 A;  2CR4 A;  2Y3A B;  2OQ1 A;  1H9O A;  4FBN A;  2AOA A;  2MC1 A;  3VRQ A;  1O41 A;  2MRJ A;  1F1W A;  4FL3 A;  2IUH A;  3PJP A;  2CI9 A;  2HMH A;  2RSY A;  1AOT F;  2L4K A;  4NWF A;  3HHM B;  2LQW A;  3GXX A;  2HDX A;  5EEL A;  4EY0 A;  2ROR A;  2L6K A;  3C7I A;  5DC9 A;  4JGH A;  1MW4 A;  4DGX A;  1SPR A;  2BBU A;  1AD5 A;  2ABL A;  1BKM A;  4GWF A;  1OO4 A;  1Z3K A;  3GQI B;  4E93 A;  4EIH A;  1RPY A;  3BUM B;  1Y57 A;  2Y1N A;  1AYA A;  4QSY A;  5J3X A;  4F59 A;  1SHD A;  1JYR A;  5KAZ A;  1BHH B;  2ECD A;  2GSB A;  4E68 A;  2PTK A;  2FO0 A;  4A4B A;  2CS0 A;  1IJR A;  2EO6 A;  3US4 A;  1LCJ A;  3UYO A;  4NWG A;  1P13 A;  2MRK A;  1SPS A;  3IN7 A;  3VRN A;  1A07 A;  2CRH A;  3ZNI A;  2LQN A;  2CIA A;  1LUI A;  2H46 E;  3PLF B;  3HCK A;  1BFI A;  3EAC A;  1A1B A;  3VS7 A;  1FU5 A;  3UF4 A;  5CDW A;  1O43 A;  1LUK A;  3VS4 A;  5I6V A;  4LUE A;  1BKL A;  2IUI A;  1O4A A;  1YVL A;  1MIL A;  3QWX X;  1B47 A;  3OVE A;  2JYQ A;  1O4E A;  1LKL A;  1IS0 A;  1AOU F;  2C0O A;  2HUW A;  4F5B A;  1BFJ A;  3S8N A;  3CXL A;  3VGO A;  4K45 A;  2K79 B;  1AB2 A;  1BHF A;  4P9V A;  2LNX A;  1TCE A;  3VS5 A;  3EAZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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