1OO4A

P395s mutant of the p85 regulatory subunit of the n-terminal src homology 2 domain of pi3-kinase complexed to a peptide derived from pdgfr
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
111
structure length
111
Chain Sequence
GMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKSIKIFHRDGKYGFSDSLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear magnetic resonance structure of the P395S mutant of the N-SH2 domain of the p85 subunit of PI3 kinase: an SH2 domain with altered specificity
pubmed doi rcsb
molecule tags Protein binding
source organism Bos taurus
molecule keywords Phosphatidylinositol 3-kinase regulatory alpha subunit
total genus 16
structure length 111
sequence length 111
ec nomenclature
pdb deposition date 2003-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1oo4A00
3MXYA 2HDVA 1RPYA 2IZVA 1JYUA 1O4CA 2EL8A 1X0NA 2MC1A 2OQ1A 1I3ZA 1KSWA 1QADA 3IMJA 4EY0A 3OV1A 3VRPA 3MAZA 1FYRA 1SPRA 3VS4A 2MQIA 2L4KA 1MILA 2MRJA 1O4PA 3VRYA 3US4A 2EU0A 1Z3KA 4DGPA 1BMBA 2EYYA 1CSYA 3BKBA 4OHEA 1O4RA 4OHIA 3GQIB 2EYZA 1O41A 1O4LA 1F1WA 4OHHA 2PNAA 3OB2B 3BUWB 5EHPA 2H8HA 2DVJA 3BUOB 1AYCA 2GE9A 3PLFB 1XA6A 1QG1E 5EEQA 5I6VA 1SHAA 2EO3A 1O48A 1O4FA 3VS3A 4P9ZA 1D4TA 1BLKA 1UURA 2YU7A 1R1SA 1IS0A 1BKMA 1BHFA 5D0JA 3ZNIA 4X6SA 1LCJA 3MXCA 2ECDA 4H34A 2LNXA 1O45A 2JYQA 1A81A 3OB1B 1BF5A 1G83A 1SHBA 2EO6A 1D4WA 1SPSA 4OHLA 2KK6A 4GL9E 5IBMA 4D8KA 2XP1A 1RQQC 2MRKA 5BO4A 1A1CA 1FBVA 2DLYA 4H1OA 1X6CA 1NZVA 1M27A 3BUXB 3CD3A 1A08A 2LQNA 3EACA 3TL0A 3PQZA 1O43A 3QWYA 5DC4A 4L1BB 5GJHA 1LKLA 3VRZA 1QCFA 4A4BA 1O4BA 5HKWA 1H9OA 1LUMA 3IN7A 4JGHA 4U1PA 1O4MA 3N84A 2HDXA 3KFJA 3BUNB 1WQUA 3VRRA 1A09A 1K9AA 3HIZB 3VRQA 1BKLA 1AD5A 1CWDL 1O49A 4E68A 2IUIA 1JYRA 3VS1A 1FHSA 1IJRA 2RSYA 2FO0A 3BUMB 1TCEA 4LUDA 2EKXA 1KC2A 4GPLB 1O4JA 2PLDA 4K2RA 1O4DA 4OHDA 3S8LA 2C9WA 2SRCA 1AYBA 1SHDA 3VS6A 4ROJA 1BG1A 4XZ1A 2CRHA 1CSZA 4F5BA 1PICA 2HUWA 1LUKA 1P13A 3HCKA 2ABLA 1A1BA 4E93A 1BHHA 1O47A 3S9KA 2SHPA 3VS2A 2DCRA 2LNWA 1R1PA 2IUHA 1JU5A 2KNOA 1JYQA 1O4KA 1CWEA 4EIHA 1CJ1A 3IN8A 2RVFA 3UYOA 1GHUA 3S8NA 1JWOA 1BHHB 1O4EA 1F2FA 4K45A 3OVEA 2AUGA 5EHRA 1X27A 1KA7A 4F5AA 4P9VA 2GSBA 1O46A 3CWGA 3IMDA 4M4ZA 1HCSB 3TKZA 4WWQA 1R1QA 2PTKA 3VGOA 2DX0A 2Y1MA 1FU5A 1NZLA 1BLJA 3UF4A 4FL2A 3K2MA 2PNBA 1O4OA 2VIFA 1OPLA 2RORA 3VS0A 1M61A 5J3XA 2AOAA 3S8OA 4DGXA 2AOBA 1D1ZA 2LQWA 3CXLA 4QSYA 2PLEA 2C0OA 2L6KA 5DF6A 3GXXA 1O42A 2B3OA 2LCTA 1SKJA 1O4NA 2YSXA 4K44A 1A1AA 4TZIA 1LKKA 2H5KA 1LCKA 4NWGA 1FU6A 1B47A 1TZEE 3M7FA 2K7AB 1O4GA 2CBLA 1FBZA 3PSJA 3NHNA 2CIAA 1A1EA 2CI8A 1AB2A 3CBLA 2EYVA 5EELA 1OO3A 2H46E 3GXWA 4FBNA 5GJIA 2HCKA 3C7IA 3QWXX 3VROA 4GWFA 1O4AA 1UUSA 1LUNA 2FCIA 2OZOA 2Y3AB 3T04A 1O44A 2IUGA 1A07A 4LUEA 5AXIA 5AULA 3WA4A 3PJPA 1AOTF 5HKYA 2CI9A 5DC0B 1KA6A 1BFIA 5HKZA 2DM0A 1LUIA 2Y1NA 2DLZA 1NRVA 3HHMB 4JE4A 2HMHA 4F59A 5IBSA 1O4HA 2C0IA 2ETZA 1OO4A 2BBUA 3VS5A 4JEGA 3N8MA 2L3TA 1YVLA 5DC9A 5CDWA 1O4IA 3PFVA 1RJAA 5KAZA 1BM2A 3VS7A 2CR4A 1GRIA 3VRNA 2C0TA 1YVHA 2MK2A 4U17A 1AOUF 4K11A 1Y57A 2QMSA 4A4CA 1FMKA 1HCTB 1OPKA 2CS0A 3PSKA 1MW4A 2EOBA 2K79B 4NWFA 3OP0A 3PS5A 1Y1UA 3EAZA 1AYAA 1ZFPE 2RMXA 1AYDA 4FL3A 1BFJA 1O4QA 5EG3B 3N7YA 4XZ0A
chains in the Genus database with same CATH superfamily
2LRAA 3MXYA 2HDVA 1RPYA 2IZVA 1JYUA 1O4CA 2EL8A 1X0NA 2MC1A 2OQ1A 1I3ZA 1KSWA 1QADA 3IMJA 4EY0A 3OV1A 3VRPA 3MAZA 1FYRA 1SPRA 3VS4A 2MQIA 2L4KA 1MILA 2MRJA 1O4PA 3VRYA 3US4A 2EU0A 1Z3KA 4DGPA 1BMBA 2EYYA 1CSYA 3BKBA 4OHEA 1O4RA 4OHIA 3GQIB 2EYZA 1O41A 1O4LA 1F1WA 4OHHA 2PNAA 3OB2B 3BUWB 5EHPA 2H8HA 2DVJA 3BUOB 1AYCA 2GE9A 3PLFB 3K2TA 1XA6A 1QG1E 5EEQA 5I6VA 1SHAA 2EO3A 1O48A 1O4FA 3VS3A 4P9ZA 1D4TA 1BLKA 1UURA 2YU7A 1R1SA 1IS0A 1BKMA 1BHFA 5D0JA 3ZNIA 4X6SA 1LCJA 3MXCA 2ECDA 4H34A 2LNXA 1O45A 2JYQA 1A81A 3OB1B 1BF5A 1G83A 1SHBA 2EO6A 1D4WA 1SPSA 4OHLA 2KK6A 4GL9E 5IBMA 4D8KA 2XP1A 1RQQC 2MRKA 5BO4A 1A1CA 1FBVA 2DLYA 4H1OA 1X6CA 1NZVA 1M27A 3BUXB 3CD3A 1A08A 2LQNA 3EACA 3TL0A 3PQZA 1O43A 3QWYA 5DC4A 4L1BB 5GJHA 1LKLA 3VRZA 1QCFA 4A4BA 1O4BA 5HKWA 1H9OA 1LUMA 3IN7A 3LYVA 4JGHA 4U1PA 1O4MA 3N84A 2HDXA 3KFJA 3BUNB 1WQUA 3VRRA 1A09A 1K9AA 3HIZB 3VRQA 1BKLA 1AD5A 1CWDL 1O49A 4E68A 2IUIA 1JYRA 3VS1A 1FHSA 1IJRA 2RSYA 2FO0A 3BUMB 1TCEA 4LUDA 2EKXA 1KC2A 4GPLB 1O4JA 2PLDA 4K2RA 1O4DA 4OHDA 3S8LA 2C9WA 2SRCA 1AYBA 1SHDA 3VS6A 4ROJA 1BG1A 4XZ1A 2CRHA 1CSZA 4F5BA 1PICA 2HUWA 1LUKA 1P13A 3HCKA 2ABLA 1A1BA 4E93A 1BHHA 1O47A 3S9KA 2SHPA 3VS2A 2DCRA 2LNWA 1R1PA 2IUHA 1JU5A 2KNOA 1JYQA 1O4KA 1CWEA 4EIHA 1CJ1A 3IN8A 2RVFA 3UYOA 1GHUA 3S8NA 1JWOA 1BHHB 1O4EA 1F2FA 4K45A 3OVEA 2AUGA 5EHRA 1X27A 1KA7A 4F5AA 4P9VA 2GSBA 1O46A 3CWGA 3IMDA 4M4ZA 1HCSB 3TKZA 4WWQA 1R1QA 2PTKA 3VGOA 2KGYA 2DX0A 2Y1MA 1FU5A 1NZLA 1BLJA 3UF4A 4FL2A 3K2MA 2PNBA 1O4OA 2VIFA 1OPLA 2RORA 3VS0A 1M61A 5J3XA 2AOAA 3S8OA 4DGXA 2AOBA 1D1ZA 2LQWA 3CXLA 4QSYA 2PLEA 2C0OA 2L6KA 5DF6A 3GXXA 1O42A 2B3OA 2LCTA 1SKJA 1O4NA 2YSXA 4K44A 1A1AA 4TZIA 1LKKA 2H5KA 1LCKA 4NWGA 1FU6A 1B47A 1TZEE 3M7FA 2K7AB 1O4GA 2CBLA 1FBZA 3PSJA 3NHNA 2CIAA 1A1EA 2CI8A 1AB2A 3CBLA 2EYVA 5EELA 1OO3A 2H46E 3GXWA 4FBNA 5GJIA 2HCKA 3C7IA 3QWXX 3VROA 4GWFA 1O4AA 1UUSA 1LUNA 2FCIA 2OZOA 2Y3AB 3T04A 1O44A 2IUGA 1A07A 4LUEA 5AXIA 5AULA 3WA4A 3PJPA 1AOTF 5HKYA 2CI9A 5DC0B 1KA6A 1BFIA 5HKZA 2DM0A 1LUIA 2Y1NA 2DLZA 1NRVA 3HHMB 4JE4A 2HMHA 4F59A 5IBSA 1O4HA 2C0IA 2ETZA 1OO4A 2BBUA 3VS5A 4JEGA 3N8MA 2L3TA 1YVLA 5DC9A 5CDWA 1O4IA 3PFVA 1RJAA 5KAZA 1BM2A 3VS7A 2CR4A 1GRIA 3VRNA 2C0TA 1YVHA 2MK2A 4U17A 1AOUF 4K11A 1Y57A 2QMSA 4A4CA 1FMKA 1HCTB 1OPKA 2CS0A 3PSKA 1MW4A 2EOBA 2K79B 4NWFA 3OP0A 3PS5A 1Y1UA 3EAZA 1AYAA 1ZFPE 2RMXA 1AYDA 4FL3A 1BFJA 1O4QA 5EG3B 3N7YA 4XZ0A
chains in the Genus database with same CATH topology
3MXYA 2HDVA 1RPYA 2IZVA 1JYUA 1O4CA 2EL8A 1X0NA 2MC1A 2OQ1A 1I3ZA 1KSWA 1QADA 3IMJA 4EY0A 3OV1A 3VRPA 3MAZA 1FYRA 1SPRA 3VS4A 2MQIA 2L4KA 1MILA 2MRJA 1O4PA 3VRYA 3US4A 2EU0A 1Z3KA 4DGPA 1BMBA 2EYYA 1CSYA 3BKBA 4OHEA 1O4RA 4OHIA 3GQIB 2EYZA 1O41A 1O4LA 1F1WA 4OHHA 2PNAA 3OB2B 3BUWB 5EHPA 2H8HA 2DVJA 3BUOB 1AYCA 2GE9A 3PLFB 1XA6A 1QG1E 5EEQA 5I6VA 1SHAA 2EO3A 1O48A 1O4FA 3VS3A 4P9ZA 1D4TA 1BLKA 1UURA 2YU7A 1R1SA 1IS0A 1BKMA 1BHFA 5D0JA 3ZNIA 4X6SA 1LCJA 3MXCA 2ECDA 4H34A 2LNXA 1O45A 2JYQA 1A81A 3OB1B 1BF5A 1G83A 1SHBA 2EO6A 1D4WA 1SPSA 4OHLA 2KK6A 4GL9E 5IBMA 4D8KA 2XP1A 1RQQC 2MRKA 5BO4A 1A1CA 1FBVA 2DLYA 4H1OA 1X6CA 1NZVA 1M27A 3BUXB 3CD3A 1A08A 2LQNA 3EACA 3TL0A 3PQZA 1O43A 3QWYA 5DC4A 4L1BB 5GJHA 1LKLA 3VRZA 1QCFA 4A4BA 1O4BA 5HKWA 1H9OA 1LUMA 3IN7A 4JGHA 4U1PA 1O4MA 3N84A 2HDXA 3KFJA 3BUNB 1WQUA 3VRRA 1A09A 1K9AA 3HIZB 3VRQA 1BKLA 1AD5A 1CWDL 1O49A 4E68A 2IUIA 1JYRA 3VS1A 1FHSA 1IJRA 2RSYA 2FO0A 3BUMB 1TCEA 4LUDA 2EKXA 1KC2A 4GPLB 1O4JA 2PLDA 4K2RA 1O4DA 4OHDA 3S8LA 2C9WA 2SRCA 1AYBA 1SHDA 3VS6A 4ROJA 1BG1A 4XZ1A 2CRHA 1CSZA 4F5BA 1PICA 2HUWA 1LUKA 1P13A 3HCKA 2ABLA 1A1BA 4E93A 1BHHA 1O47A 3S9KA 2SHPA 3VS2A 2DCRA 2LNWA 1R1PA 2IUHA 1JU5A 2KNOA 1JYQA 1O4KA 1CWEA 4EIHA 1CJ1A 3IN8A 2RVFA 3UYOA 1GHUA 3S8NA 1JWOA 1BHHB 1O4EA 1F2FA 4K45A 3OVEA 2AUGA 5EHRA 1X27A 1KA7A 4F5AA 4P9VA 2GSBA 1O46A 3CWGA 3IMDA 4M4ZA 1HCSB 3TKZA 4WWQA 1R1QA 2PTKA 3VGOA 2DX0A 2Y1MA 1FU5A 1NZLA 1BLJA 3UF4A 4FL2A 3K2MA 2PNBA 1O4OA 2VIFA 1OPLA 2RORA 3VS0A 1M61A 5J3XA 2AOAA 3S8OA 4DGXA 2AOBA 1D1ZA 2LQWA 3CXLA 4QSYA 2PLEA 2C0OA 2L6KA 5DF6A 3GXXA 1O42A 2B3OA 2LCTA 1SKJA 1O4NA 2YSXA 4K44A 1A1AA 4TZIA 1LKKA 2H5KA 1LCKA 4NWGA 1FU6A 1B47A 1TZEE 3M7FA 2K7AB 1O4GA 2CBLA 1FBZA 3PSJA 3NHNA 2CIAA 1A1EA 2CI8A 1AB2A 3CBLA 2EYVA 5EELA 1OO3A 2H46E 3GXWA 4FBNA 5GJIA 2HCKA 3C7IA 3QWXX 3VROA 4GWFA 1O4AA 1UUSA 1LUNA 2FCIA 2OZOA 2Y3AB 3T04A 1O44A 2IUGA 1A07A 4LUEA 5AXIA 5AULA 3WA4A 3PJPA 1AOTF 5HKYA 2CI9A 5DC0B 1KA6A 1BFIA 5HKZA 2DM0A 1LUIA 2Y1NA 2DLZA 1NRVA 3HHMB 4JE4A 2HMHA 4F59A 5IBSA 1O4HA 2C0IA 2ETZA 1OO4A 2BBUA 3VS5A 4JEGA 3N8MA 2L3TA 1YVLA 5DC9A 5CDWA 1O4IA 3PFVA 1RJAA 5KAZA 1BM2A 3VS7A 2CR4A 1GRIA 3VRNA 2C0TA 1YVHA 2MK2A 4U17A 1AOUF 4K11A 1Y57A 2QMSA 4A4CA 1FMKA 1HCTB 1OPKA 2CS0A 3PSKA 1MW4A 2EOBA 2K79B 4NWFA 3OP0A 3PS5A 1Y1UA 3EAZA 1AYAA 1ZFPE 2RMXA 1AYDA 4FL3A 1BFJA 1O4QA 5EG3B 3N7YA 4XZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MXY A;  2HDV A;  1RPY A;  2IZV A;  1JYU A;  1O4C A;  2EL8 A;  1X0N A;  2MC1 A;  2OQ1 A;  1I3Z A;  1KSW A;  1QAD A;  3IMJ A;  4EY0 A;  3OV1 A;  3VRP A;  3MAZ A;  1FYR A;  1SPR A;  3VS4 A;  2MQI A;  2L4K A;  1MIL A;  2MRJ A;  1O4P A;  3VRY A;  3US4 A;  2EU0 A;  1Z3K A;  4DGP A;  1BMB A;  2EYY A;  1CSY A;  3BKB A;  4OHE A;  1O4R A;  4OHI A;  3GQI B;  2EYZ A;  1O41 A;  1O4L A;  1F1W A;  4OHH A;  2PNA A;  3OB2 B;  3BUW B;  5EHP A;  2H8H A;  2DVJ A;  3BUO B;  1AYC A;  2GE9 A;  3PLF B;  1XA6 A;  1QG1 E;  5EEQ A;  5I6V A;  1SHA A;  2EO3 A;  1O48 A;  1O4F A;  3VS3 A;  4P9Z A;  1D4T A;  1BLK A;  1UUR A;  2YU7 A;  1R1S A;  1IS0 A;  1BKM A;  1BHF A;  5D0J A;  3ZNI A;  4X6S A;  1LCJ A;  3MXC A;  2ECD A;  4H34 A;  2LNX A;  1O45 A;  2JYQ A;  1A81 A;  3OB1 B;  1BF5 A;  1G83 A;  1SHB A;  2EO6 A;  1D4W A;  1SPS A;  4OHL A;  2KK6 A;  4GL9 E;  5IBM A;  4D8K A;  2XP1 A;  1RQQ C;  2MRK A;  5BO4 A;  1A1C A;  1FBV A;  2DLY A;  4H1O A;  1X6C A;  1NZV A;  1M27 A;  3BUX B;  3CD3 A;  1A08 A;  2LQN A;  3EAC A;  3TL0 A;  3PQZ A;  1O43 A;  3QWY A;  5DC4 A;  4L1B B;  5GJH A;  1LKL A;  3VRZ A;  1QCF A;  4A4B A;  1O4B A;  5HKW A;  1H9O A;  1LUM A;  3IN7 A;  4JGH A;  4U1P A;  1O4M A;  3N84 A;  2HDX A;  3KFJ A;  3BUN B;  1WQU A;  3VRR A;  1A09 A;  1K9A A;  3HIZ B;  3VRQ A;  1BKL A;  1AD5 A;  1CWD L;  1O49 A;  4E68 A;  2IUI A;  1JYR A;  3VS1 A;  1FHS A;  1IJR A;  2RSY A;  2FO0 A;  3BUM B;  1TCE A;  4LUD A;  2EKX A;  1KC2 A;  4GPL B;  1O4J A;  2PLD A;  4K2R A;  1O4D A;  4OHD A;  3S8L A;  2C9W A;  2SRC A;  1AYB A;  1SHD A;  3VS6 A;  4ROJ A;  1BG1 A;  4XZ1 A;  2CRH A;  1CSZ A;  4F5B A;  1PIC A;  2HUW A;  1LUK A;  1P13 A;  3HCK A;  2ABL A;  1A1B A;  4E93 A;  1BHH A;  1O47 A;  3S9K A;  2SHP A;  3VS2 A;  2DCR A;  2LNW A;  1R1P A;  2IUH A;  1JU5 A;  2KNO A;  1JYQ A;  1O4K A;  1CWE A;  4EIH A;  1CJ1 A;  3IN8 A;  2RVF A;  3UYO A;  1GHU A;  3S8N A;  1JWO A;  1BHH B;  1O4E A;  1F2F A;  4K45 A;  3OVE A;  2AUG A;  5EHR A;  1X27 A;  1KA7 A;  4F5A A;  4P9V A;  2GSB A;  1O46 A;  3CWG A;  3IMD A;  4M4Z A;  1HCS B;  3TKZ A;  4WWQ A;  1R1Q A;  2PTK A;  3VGO A;  2DX0 A;  2Y1M A;  1FU5 A;  1NZL A;  1BLJ A;  3UF4 A;  4FL2 A;  3K2M A;  2PNB A;  1O4O A;  2VIF A;  1OPL A;  2ROR A;  3VS0 A;  1M61 A;  5J3X A;  2AOA A;  3S8O A;  4DGX A;  2AOB A;  1D1Z A;  2LQW A;  3CXL A;  4QSY A;  2PLE A;  2C0O A;  2L6K A;  5DF6 A;  3GXX A;  1O42 A;  2B3O A;  2LCT A;  1SKJ A;  1O4N A;  2YSX A;  4K44 A;  1A1A A;  4TZI A;  1LKK A;  2H5K A;  1LCK A;  4NWG A;  1FU6 A;  1B47 A;  1TZE E;  3M7F A;  2K7A B;  1O4G A;  2CBL A;  1FBZ A;  3PSJ A;  3NHN A;  2CIA A;  1A1E A;  2CI8 A;  1AB2 A;  3CBL A;  2EYV A;  5EEL A;  1OO3 A;  2H46 E;  3GXW A;  4FBN A;  5GJI A;  2HCK A;  3C7I A;  3QWX X;  3VRO A;  4GWF A;  1O4A A;  1UUS A;  1LUN A;  2FCI A;  2OZO A;  2Y3A B;  3T04 A;  1O44 A;  2IUG A;  1A07 A;  4LUE A;  5AXI A;  5AUL A;  3WA4 A;  3PJP A;  1AOT F;  5HKY A;  2CI9 A;  5DC0 B;  1KA6 A;  1BFI A;  5HKZ A;  2DM0 A;  1LUI A;  2Y1N A;  2DLZ A;  1NRV A;  3HHM B;  4JE4 A;  2HMH A;  4F59 A;  5IBS A;  1O4H A;  2C0I A;  2ETZ A;  1OO4 A;  2BBU A;  3VS5 A;  4JEG A;  3N8M A;  2L3T A;  1YVL A;  5DC9 A;  5CDW A;  1O4I A;  3PFV A;  1RJA A;  5KAZ A;  1BM2 A;  3VS7 A;  2CR4 A;  1GRI A;  3VRN A;  2C0T A;  1YVH A;  2MK2 A;  4U17 A;  1AOU F;  4K11 A;  1Y57 A;  2QMS A;  4A4C A;  1FMK A;  1HCT B;  1OPK A;  2CS0 A;  3PSK A;  1MW4 A;  2EOB A;  2K79 B;  4NWF A;  3OP0 A;  3PS5 A;  1Y1U A;  3EAZ A;  1AYA A;  1ZFP E;  2RMX A;  1AYD A;  4FL3 A;  1BFJ A;  1O4Q A;  5EG3 B;  3N7Y A;  4XZ0 A; 
#chains in the Genus database with same CATH topology
 2LRA A;  3MXY A;  2HDV A;  1RPY A;  2IZV A;  1JYU A;  1O4C A;  2EL8 A;  1X0N A;  2MC1 A;  2OQ1 A;  1I3Z A;  1KSW A;  1QAD A;  3IMJ A;  4EY0 A;  3OV1 A;  3VRP A;  3MAZ A;  1FYR A;  1SPR A;  3VS4 A;  2MQI A;  2L4K A;  1MIL A;  2MRJ A;  1O4P A;  3VRY A;  3US4 A;  2EU0 A;  1Z3K A;  4DGP A;  1BMB A;  2EYY A;  1CSY A;  3BKB A;  4OHE A;  1O4R A;  4OHI A;  3GQI B;  2EYZ A;  1O41 A;  1O4L A;  1F1W A;  4OHH A;  2PNA A;  3OB2 B;  3BUW B;  5EHP A;  2H8H A;  2DVJ A;  3BUO B;  1AYC A;  2GE9 A;  3PLF B;  3K2T A;  1XA6 A;  1QG1 E;  5EEQ A;  5I6V A;  1SHA A;  2EO3 A;  1O48 A;  1O4F A;  3VS3 A;  4P9Z A;  1D4T A;  1BLK A;  1UUR A;  2YU7 A;  1R1S A;  1IS0 A;  1BKM A;  1BHF A;  5D0J A;  3ZNI A;  4X6S A;  1LCJ A;  3MXC A;  2ECD A;  4H34 A;  2LNX A;  1O45 A;  2JYQ A;  1A81 A;  3OB1 B;  1BF5 A;  1G83 A;  1SHB A;  2EO6 A;  1D4W A;  1SPS A;  4OHL A;  2KK6 A;  4GL9 E;  5IBM A;  4D8K A;  2XP1 A;  1RQQ C;  2MRK A;  5BO4 A;  1A1C A;  1FBV A;  2DLY A;  4H1O A;  1X6C A;  1NZV A;  1M27 A;  3BUX B;  3CD3 A;  1A08 A;  2LQN A;  3EAC A;  3TL0 A;  3PQZ A;  1O43 A;  3QWY A;  5DC4 A;  4L1B B;  5GJH A;  1LKL A;  3VRZ A;  1QCF A;  4A4B A;  1O4B A;  5HKW A;  1H9O A;  1LUM A;  3IN7 A;  3LYV A;  4JGH A;  4U1P A;  1O4M A;  3N84 A;  2HDX A;  3KFJ A;  3BUN B;  1WQU A;  3VRR A;  1A09 A;  1K9A A;  3HIZ B;  3VRQ A;  1BKL A;  1AD5 A;  1CWD L;  1O49 A;  4E68 A;  2IUI A;  1JYR A;  3VS1 A;  1FHS A;  1IJR A;  2RSY A;  2FO0 A;  3BUM B;  1TCE A;  4LUD A;  2EKX A;  1KC2 A;  4GPL B;  1O4J A;  2PLD A;  4K2R A;  1O4D A;  4OHD A;  3S8L A;  2C9W A;  2SRC A;  1AYB A;  1SHD A;  3VS6 A;  4ROJ A;  1BG1 A;  4XZ1 A;  2CRH A;  1CSZ A;  4F5B A;  1PIC A;  2HUW A;  1LUK A;  1P13 A;  3HCK A;  2ABL A;  1A1B A;  4E93 A;  1BHH A;  1O47 A;  3S9K A;  2SHP A;  3VS2 A;  2DCR A;  2LNW A;  1R1P A;  2IUH A;  1JU5 A;  2KNO A;  1JYQ A;  1O4K A;  1CWE A;  4EIH A;  1CJ1 A;  3IN8 A;  2RVF A;  3UYO A;  1GHU A;  3S8N A;  1JWO A;  1BHH B;  1O4E A;  1F2F A;  4K45 A;  3OVE A;  2AUG A;  5EHR A;  1X27 A;  1KA7 A;  4F5A A;  4P9V A;  2GSB A;  1O46 A;  3CWG A;  3IMD A;  4M4Z A;  1HCS B;  3TKZ A;  4WWQ A;  1R1Q A;  2PTK A;  3VGO A;  2KGY A;  2DX0 A;  2Y1M A;  1FU5 A;  1NZL A;  1BLJ A;  3UF4 A;  4FL2 A;  3K2M A;  2PNB A;  1O4O A;  2VIF A;  1OPL A;  2ROR A;  3VS0 A;  1M61 A;  5J3X A;  2AOA A;  3S8O A;  4DGX A;  2AOB A;  1D1Z A;  2LQW A;  3CXL A;  4QSY A;  2PLE A;  2C0O A;  2L6K A;  5DF6 A;  3GXX A;  1O42 A;  2B3O A;  2LCT A;  1SKJ A;  1O4N A;  2YSX A;  4K44 A;  1A1A A;  4TZI A;  1LKK A;  2H5K A;  1LCK A;  4NWG A;  1FU6 A;  1B47 A;  1TZE E;  3M7F A;  2K7A B;  1O4G A;  2CBL A;  1FBZ A;  3PSJ A;  3NHN A;  2CIA A;  1A1E A;  2CI8 A;  1AB2 A;  3CBL A;  2EYV A;  5EEL A;  1OO3 A;  2H46 E;  3GXW A;  4FBN A;  5GJI A;  2HCK A;  3C7I A;  3QWX X;  3VRO A;  4GWF A;  1O4A A;  1UUS A;  1LUN A;  2FCI A;  2OZO A;  2Y3A B;  3T04 A;  1O44 A;  2IUG A;  1A07 A;  4LUE A;  5AXI A;  5AUL A;  3WA4 A;  3PJP A;  1AOT F;  5HKY A;  2CI9 A;  5DC0 B;  1KA6 A;  1BFI A;  5HKZ A;  2DM0 A;  1LUI A;  2Y1N A;  2DLZ A;  1NRV A;  3HHM B;  4JE4 A;  2HMH A;  4F59 A;  5IBS A;  1O4H A;  2C0I A;  2ETZ A;  1OO4 A;  2BBU A;  3VS5 A;  4JEG A;  3N8M A;  2L3T A;  1YVL A;  5DC9 A;  5CDW A;  1O4I A;  3PFV A;  1RJA A;  5KAZ A;  1BM2 A;  3VS7 A;  2CR4 A;  1GRI A;  3VRN A;  2C0T A;  1YVH A;  2MK2 A;  4U17 A;  1AOU F;  4K11 A;  1Y57 A;  2QMS A;  4A4C A;  1FMK A;  1HCT B;  1OPK A;  2CS0 A;  3PSK A;  1MW4 A;  2EOB A;  2K79 B;  4NWF A;  3OP0 A;  3PS5 A;  1Y1U A;  3EAZ A;  1AYA A;  1ZFP E;  2RMX A;  1AYD A;  4FL3 A;  1BFJ A;  1O4Q A;  5EG3 B;  3N7Y A;  4XZ0 A; 
#chains in the Genus database with same CATH homology
 3MXY A;  2HDV A;  1RPY A;  2IZV A;  1JYU A;  1O4C A;  2EL8 A;  1X0N A;  2MC1 A;  2OQ1 A;  1I3Z A;  1KSW A;  1QAD A;  3IMJ A;  4EY0 A;  3OV1 A;  3VRP A;  3MAZ A;  1FYR A;  1SPR A;  3VS4 A;  2MQI A;  2L4K A;  1MIL A;  2MRJ A;  1O4P A;  3VRY A;  3US4 A;  2EU0 A;  1Z3K A;  4DGP A;  1BMB A;  2EYY A;  1CSY A;  3BKB A;  4OHE A;  1O4R A;  4OHI A;  3GQI B;  2EYZ A;  1O41 A;  1O4L A;  1F1W A;  4OHH A;  2PNA A;  3OB2 B;  3BUW B;  5EHP A;  2H8H A;  2DVJ A;  3BUO B;  1AYC A;  2GE9 A;  3PLF B;  1XA6 A;  1QG1 E;  5EEQ A;  5I6V A;  1SHA A;  2EO3 A;  1O48 A;  1O4F A;  3VS3 A;  4P9Z A;  1D4T A;  1BLK A;  1UUR A;  2YU7 A;  1R1S A;  1IS0 A;  1BKM A;  1BHF A;  5D0J A;  3ZNI A;  4X6S A;  1LCJ A;  3MXC A;  2ECD A;  4H34 A;  2LNX A;  1O45 A;  2JYQ A;  1A81 A;  3OB1 B;  1BF5 A;  1G83 A;  1SHB A;  2EO6 A;  1D4W A;  1SPS A;  4OHL A;  2KK6 A;  4GL9 E;  5IBM A;  4D8K A;  2XP1 A;  1RQQ C;  2MRK A;  5BO4 A;  1A1C A;  1FBV A;  2DLY A;  4H1O A;  1X6C A;  1NZV A;  1M27 A;  3BUX B;  3CD3 A;  1A08 A;  2LQN A;  3EAC A;  3TL0 A;  3PQZ A;  1O43 A;  3QWY A;  5DC4 A;  4L1B B;  5GJH A;  1LKL A;  3VRZ A;  1QCF A;  4A4B A;  1O4B A;  5HKW A;  1H9O A;  1LUM A;  3IN7 A;  4JGH A;  4U1P A;  1O4M A;  3N84 A;  2HDX A;  3KFJ A;  3BUN B;  1WQU A;  3VRR A;  1A09 A;  1K9A A;  3HIZ B;  3VRQ A;  1BKL A;  1AD5 A;  1CWD L;  1O49 A;  4E68 A;  2IUI A;  1JYR A;  3VS1 A;  1FHS A;  1IJR A;  2RSY A;  2FO0 A;  3BUM B;  1TCE A;  4LUD A;  2EKX A;  1KC2 A;  4GPL B;  1O4J A;  2PLD A;  4K2R A;  1O4D A;  4OHD A;  3S8L A;  2C9W A;  2SRC A;  1AYB A;  1SHD A;  3VS6 A;  4ROJ A;  1BG1 A;  4XZ1 A;  2CRH A;  1CSZ A;  4F5B A;  1PIC A;  2HUW A;  1LUK A;  1P13 A;  3HCK A;  2ABL A;  1A1B A;  4E93 A;  1BHH A;  1O47 A;  3S9K A;  2SHP A;  3VS2 A;  2DCR A;  2LNW A;  1R1P A;  2IUH A;  1JU5 A;  2KNO A;  1JYQ A;  1O4K A;  1CWE A;  4EIH A;  1CJ1 A;  3IN8 A;  2RVF A;  3UYO A;  1GHU A;  3S8N A;  1JWO A;  1BHH B;  1O4E A;  1F2F A;  4K45 A;  3OVE A;  2AUG A;  5EHR A;  1X27 A;  1KA7 A;  4F5A A;  4P9V A;  2GSB A;  1O46 A;  3CWG A;  3IMD A;  4M4Z A;  1HCS B;  3TKZ A;  4WWQ A;  1R1Q A;  2PTK A;  3VGO A;  2DX0 A;  2Y1M A;  1FU5 A;  1NZL A;  1BLJ A;  3UF4 A;  4FL2 A;  3K2M A;  2PNB A;  1O4O A;  2VIF A;  1OPL A;  2ROR A;  3VS0 A;  1M61 A;  5J3X A;  2AOA A;  3S8O A;  4DGX A;  2AOB A;  1D1Z A;  2LQW A;  3CXL A;  4QSY A;  2PLE A;  2C0O A;  2L6K A;  5DF6 A;  3GXX A;  1O42 A;  2B3O A;  2LCT A;  1SKJ A;  1O4N A;  2YSX A;  4K44 A;  1A1A A;  4TZI A;  1LKK A;  2H5K A;  1LCK A;  4NWG A;  1FU6 A;  1B47 A;  1TZE E;  3M7F A;  2K7A B;  1O4G A;  2CBL A;  1FBZ A;  3PSJ A;  3NHN A;  2CIA A;  1A1E A;  2CI8 A;  1AB2 A;  3CBL A;  2EYV A;  5EEL A;  1OO3 A;  2H46 E;  3GXW A;  4FBN A;  5GJI A;  2HCK A;  3C7I A;  3QWX X;  3VRO A;  4GWF A;  1O4A A;  1UUS A;  1LUN A;  2FCI A;  2OZO A;  2Y3A B;  3T04 A;  1O44 A;  2IUG A;  1A07 A;  4LUE A;  5AXI A;  5AUL A;  3WA4 A;  3PJP A;  1AOT F;  5HKY A;  2CI9 A;  5DC0 B;  1KA6 A;  1BFI A;  5HKZ A;  2DM0 A;  1LUI A;  2Y1N A;  2DLZ A;  1NRV A;  3HHM B;  4JE4 A;  2HMH A;  4F59 A;  5IBS A;  1O4H A;  2C0I A;  2ETZ A;  1OO4 A;  2BBU A;  3VS5 A;  4JEG A;  3N8M A;  2L3T A;  1YVL A;  5DC9 A;  5CDW A;  1O4I A;  3PFV A;  1RJA A;  5KAZ A;  1BM2 A;  3VS7 A;  2CR4 A;  1GRI A;  3VRN A;  2C0T A;  1YVH A;  2MK2 A;  4U17 A;  1AOU F;  4K11 A;  1Y57 A;  2QMS A;  4A4C A;  1FMK A;  1HCT B;  1OPK A;  2CS0 A;  3PSK A;  1MW4 A;  2EOB A;  2K79 B;  4NWF A;  3OP0 A;  3PS5 A;  1Y1U A;  3EAZ A;  1AYA A;  1ZFP E;  2RMX A;  1AYD A;  4FL3 A;  1BFJ A;  1O4Q A;  5EG3 B;  3N7Y A;  4XZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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