1SPRA

Binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
103
structure length
103
Chain Sequence
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
pubmed doi rcsb
molecule tags Transferase(phosphotransferase)
source organism Rous sarcoma virus
molecule keywords SRC TYROSINE KINASE SH2 DOMAIN
total genus 24
structure length 103
sequence length 103
chains with identical sequence B, C, D
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1993-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1sprA00
1O4QA 2XP1A 2FCIA 1O42A 1SHDA 3GXXA 4QSYA 1I3ZA 1F1WA 1TCEA 1O46A 1X0NA 1LCKA 1MW4A 2HDXA 3C7IA 1RJAA 3NHNA 1AYCA 1O4EA 4K11A 3OV1A 2FO0A 4H1OA 3VS3A 5EG3B 3IMDA 1A1EA 1BKLA 3OP0A 1LUKA 3VGOA 1BHFA 3VRQA 2EOBA 4JE4A 1O4OA 2CI8A 2DM0A 1SHBA 3N84A 2OQ1A 1O4LA 4XZ1A 1G83A 2ABLA 2HMHA 1A1BA 5IBMA 1O4BA 1LKLA 1IS0A 4OHEA 1A09A 3QWXX 2PNAA 1BLJA 1NZVA 2KNOA 2EYVA 4F59A 2CIAA 4D8KA 5EHRA 1LKKA 1X27A 1GHUA 3VRPA 3VRYA 3WA4A 3VRNA 1SPSA 1PICA 4K2RA 2EL8A 4GWFA 3VRRA 1BKMA 3S9KA 2K7AB 1O4MA 1JWOA 3VS4A 3BUNB 1OPKA 1NRVA 3VRZA 2YU7A 1GRIA 2DCRA 4L1BB 1Z3KA 2RMXA 1H9OA 1OPLA 2Y3AB 4FBNA 3EAZA 1O49A 2EYYA 1QG1E 1QCFA 2H46E 5EHPA 1BG1A 2IUIA 2PLDA 2PLEA 1BF5A 2DVJA 1UURA 3S8NA 1LCJA 1O4NA 2SHPA 3OB2B 3M7FA 3PFVA 1JYQA 4E68A 2IUGA 1AYBA 1O4RA 3BKBA 1O48A 1O4JA 4ROJA 1CSYA 4U17A 1X6CA 3K2MA 2OZOA 3T04A 3MXCA 4NWGA 4X6SA 2LQNA 1NZLA 3UF4A 3MXYA 4LUEA 1BLKA 1SHAA 1O45A 4FL2A 3US4A 1B47A 4NWFA 3BUWB 1F2FA 3OVEA 4A4BA 2EU0A 1FYRA 2MRKA 3HHMB 2PTKA 5DC9A 2KK6A 5EELA 2HUWA 1BFJA 1FHSA 1O4CA 5DC4A 1O4GA 3QWYA 1JU5A 2PNBA 1LUNA 2CBLA 3GQIB 1O4IA 2IUHA 1A1CA 2BBUA 1K9AA 3VS0A 5HKZA 2B3OA 5J3XA 1A08A 1AOUF 1D1ZA 1HCSB 3N8MA 1CJ1A 2MC1A 1BM2A 2C0IA 3GXWA 1BHHA 4A4CA 4H34A 2LNWA 2ECDA 3VROA 1BMBA 2GSBA 1RPYA 4DGXA 3BUXB 4WWQA 2AOBA 1KA7A 1JYRA 1O4HA 1KA6A 1YVHA 2JYQA 3S8LA 3UYOA 2MRJA 3IMJA 3VS7A 2CS0A 2YSXA 1O4FA 2H5KA 4XZ0A 2HDVA 2Y1NA 1TZEE 2GE9A 5BO4A 5AXIA 1O4DA 2H8HA 2L4KA 4GPLB 2DLZA 2CRHA 2C0OA 2Y1MA 4FL3A 3PQZA 3KFJA 3CBLA 1BHHB 4JEGA 1AB2A 1M61A 3OB1B 3PSKA 1FMKA 2MQIA 4M4ZA 4F5AA 1O4AA 1CWEA 2L6KA 3VS1A 1D4WA 1Y57A 1LUIA 2ETZA 5GJHA 1O47A 3PS5A 1YVLA 1BFIA 4K44A 1OO4A 4U1PA 1M27A 1FBVA 3MAZA 3PJPA 5DF6A 1CWDL 3ZNIA 4OHDA 1SPRA 5HKYA 1AYAA 4LUDA 1FU6A 3VS6A 1O4PA 5GJIA 2CR4A 1P13A 2C0TA 1O41A 1UUSA 2HCKA 2K79B 1HCTB 4P9VA 2C9WA 1A81A 3S8OA 3PSJA 2LNXA 1AOTF 4TZIA 4EIHA 4F5BA 3HCKA 1MILA 5I6VA 3PLFB 3BUOB 2DX0A 4EY0A 2QMSA 3CD3A 4DGPA 4E93A 1O4KA 1AYDA 2MK2A 3IN8A 1O44A 2SRCA 1LUMA 3EACA 3N7YA 1CSZA 1OO3A 1FBZA 1WQUA 1KC2A 2EO6A 4OHHA 1KSWA 5D0JA 1A1AA 2VIFA 4JGHA 2LCTA 3VS2A 1R1SA 2CI9A 3CXLA 2RORA 1D4TA 2RSYA 4P9ZA 1JYUA 2L3TA 5HKWA 1QADA 4OHIA 2RVFA 4OHLA 5AULA 3BUMB 3CWGA 4GL9E 1AD5A 2EKXA 2DLYA 2EO3A 2AOAA 3TKZA 5DC0B 5CDWA 2IZVA 5IBSA 1SKJA 5EEQA 3VS5A 2AUGA 1R1QA 1Y1UA 5KAZA 4K45A 1O43A 1IJRA 1FU5A 1R1PA 1A07A 3HIZB 3TL0A 2EYZA 3IN7A 2LQWA 1XA6A 1ZFPE 1RQQC
chains in the Genus database with same CATH superfamily
1O4QA 2XP1A 2FCIA 1O42A 1SHDA 3GXXA 4QSYA 1I3ZA 1F1WA 1TCEA 1O46A 1X0NA 1LCKA 1MW4A 2HDXA 3C7IA 1RJAA 3NHNA 1AYCA 1O4EA 4K11A 3OV1A 2FO0A 4H1OA 3VS3A 5EG3B 3IMDA 3K2TA 1A1EA 1BKLA 3OP0A 1LUKA 3VGOA 1BHFA 3VRQA 2EOBA 4JE4A 1O4OA 2CI8A 2DM0A 1SHBA 3N84A 2KGYA 2OQ1A 1O4LA 4XZ1A 1G83A 2ABLA 2HMHA 1A1BA 5IBMA 1O4BA 1LKLA 1IS0A 4OHEA 1A09A 3QWXX 2PNAA 1BLJA 1NZVA 2KNOA 2EYVA 4F59A 2CIAA 4D8KA 5EHRA 1LKKA 1X27A 1GHUA 3VRPA 3VRYA 3WA4A 3VRNA 1SPSA 1PICA 4K2RA 2EL8A 4GWFA 3VRRA 1BKMA 3S9KA 2K7AB 1O4MA 1JWOA 3VS4A 3BUNB 1OPKA 1NRVA 3VRZA 2YU7A 1GRIA 2DCRA 4L1BB 1Z3KA 2RMXA 1H9OA 1OPLA 2Y3AB 4FBNA 3EAZA 1O49A 2EYYA 1QG1E 1QCFA 2H46E 5EHPA 1BG1A 2IUIA 2PLDA 2PLEA 1BF5A 2DVJA 1UURA 3S8NA 1LCJA 1O4NA 2SHPA 3OB2B 3M7FA 3PFVA 1JYQA 4E68A 2IUGA 1AYBA 1O4RA 3BKBA 1O48A 1O4JA 4ROJA 1CSYA 4U17A 1X6CA 3K2MA 2OZOA 3T04A 3MXCA 4NWGA 4X6SA 2LQNA 1NZLA 3UF4A 3MXYA 4LUEA 1BLKA 1SHAA 1O45A 4FL2A 3US4A 1B47A 4NWFA 3BUWB 1F2FA 3OVEA 4A4BA 2EU0A 1FYRA 2MRKA 3HHMB 2PTKA 5DC9A 2KK6A 5EELA 2HUWA 1BFJA 1FHSA 1O4CA 5DC4A 1O4GA 3QWYA 1JU5A 2PNBA 1LUNA 2CBLA 3GQIB 1O4IA 2IUHA 1A1CA 2BBUA 1K9AA 3VS0A 5HKZA 2B3OA 5J3XA 1A08A 1AOUF 1D1ZA 1HCSB 3N8MA 1CJ1A 2MC1A 1BM2A 2C0IA 3GXWA 1BHHA 4A4CA 4H34A 2LNWA 2ECDA 3LYVA 3VROA 1BMBA 2GSBA 1RPYA 4DGXA 3BUXB 4WWQA 2AOBA 1KA7A 1JYRA 1O4HA 1KA6A 1YVHA 2JYQA 3S8LA 3UYOA 2MRJA 3IMJA 3VS7A 2CS0A 2YSXA 1O4FA 2H5KA 4XZ0A 2HDVA 2Y1NA 1TZEE 2GE9A 5BO4A 5AXIA 1O4DA 2H8HA 2L4KA 4GPLB 2DLZA 2CRHA 2C0OA 2Y1MA 4FL3A 3PQZA 3KFJA 3CBLA 1BHHB 4JEGA 1AB2A 1M61A 3OB1B 3PSKA 1FMKA 2MQIA 4M4ZA 4F5AA 1O4AA 1CWEA 2L6KA 3VS1A 1D4WA 1Y57A 1LUIA 2ETZA 5GJHA 1O47A 3PS5A 1YVLA 1BFIA 4K44A 1OO4A 4U1PA 1M27A 1FBVA 3MAZA 3PJPA 5DF6A 1CWDL 3ZNIA 4OHDA 1SPRA 5HKYA 1AYAA 4LUDA 1FU6A 3VS6A 1O4PA 5GJIA 2CR4A 1P13A 2C0TA 1O41A 1UUSA 2HCKA 2K79B 1HCTB 4P9VA 2C9WA 1A81A 3S8OA 3PSJA 2LNXA 1AOTF 4TZIA 4EIHA 4F5BA 3HCKA 1MILA 5I6VA 3PLFB 3BUOB 2DX0A 4EY0A 2QMSA 3CD3A 4DGPA 4E93A 1O4KA 1AYDA 2MK2A 3IN8A 1O44A 2SRCA 1LUMA 3EACA 3N7YA 1CSZA 1OO3A 1FBZA 1WQUA 1KC2A 2EO6A 4OHHA 1KSWA 5D0JA 1A1AA 2VIFA 4JGHA 2LCTA 3VS2A 1R1SA 2CI9A 3CXLA 2RORA 1D4TA 2RSYA 4P9ZA 1JYUA 2L3TA 5HKWA 1QADA 4OHIA 2RVFA 4OHLA 5AULA 3BUMB 3CWGA 4GL9E 1AD5A 2EKXA 2DLYA 2EO3A 2AOAA 3TKZA 5DC0B 5CDWA 2IZVA 5IBSA 1SKJA 5EEQA 3VS5A 2AUGA 2LRAA 1R1QA 1Y1UA 5KAZA 4K45A 1O43A 1IJRA 1FU5A 1R1PA 1A07A 3HIZB 3TL0A 2EYZA 3IN7A 2LQWA 1XA6A 1ZFPE 1RQQC
chains in the Genus database with same CATH topology
1O4QA 2XP1A 2FCIA 1O42A 1SHDA 3GXXA 4QSYA 1I3ZA 1F1WA 1TCEA 1O46A 1X0NA 1LCKA 1MW4A 2HDXA 3C7IA 1RJAA 3NHNA 1AYCA 1O4EA 4K11A 3OV1A 2FO0A 4H1OA 3VS3A 5EG3B 3IMDA 1A1EA 1BKLA 3OP0A 1LUKA 3VGOA 1BHFA 3VRQA 2EOBA 4JE4A 1O4OA 2CI8A 2DM0A 1SHBA 3N84A 2OQ1A 1O4LA 4XZ1A 1G83A 2ABLA 2HMHA 1A1BA 5IBMA 1O4BA 1LKLA 1IS0A 4OHEA 1A09A 3QWXX 2PNAA 1BLJA 1NZVA 2KNOA 2EYVA 4F59A 2CIAA 4D8KA 5EHRA 1LKKA 1X27A 1GHUA 3VRPA 3VRYA 3WA4A 3VRNA 1SPSA 1PICA 4K2RA 2EL8A 4GWFA 3VRRA 1BKMA 3S9KA 2K7AB 1O4MA 1JWOA 3VS4A 3BUNB 1OPKA 1NRVA 3VRZA 2YU7A 1GRIA 2DCRA 4L1BB 1Z3KA 2RMXA 1H9OA 1OPLA 2Y3AB 4FBNA 3EAZA 1O49A 2EYYA 1QG1E 1QCFA 2H46E 5EHPA 1BG1A 2IUIA 2PLDA 2PLEA 1BF5A 2DVJA 1UURA 3S8NA 1LCJA 1O4NA 2SHPA 3OB2B 3M7FA 3PFVA 1JYQA 4E68A 2IUGA 1AYBA 1O4RA 3BKBA 1O48A 1O4JA 4ROJA 1CSYA 4U17A 1X6CA 3K2MA 2OZOA 3T04A 3MXCA 4NWGA 4X6SA 2LQNA 1NZLA 3UF4A 3MXYA 4LUEA 1BLKA 1SHAA 1O45A 4FL2A 3US4A 1B47A 4NWFA 3BUWB 1F2FA 3OVEA 4A4BA 2EU0A 1FYRA 2MRKA 3HHMB 2PTKA 5DC9A 2KK6A 5EELA 2HUWA 1BFJA 1FHSA 1O4CA 5DC4A 1O4GA 3QWYA 1JU5A 2PNBA 1LUNA 2CBLA 3GQIB 1O4IA 2IUHA 1A1CA 2BBUA 1K9AA 3VS0A 5HKZA 2B3OA 5J3XA 1A08A 1AOUF 1D1ZA 1HCSB 3N8MA 1CJ1A 2MC1A 1BM2A 2C0IA 3GXWA 1BHHA 4A4CA 4H34A 2LNWA 2ECDA 3VROA 1BMBA 2GSBA 1RPYA 4DGXA 3BUXB 4WWQA 2AOBA 1KA7A 1JYRA 1O4HA 1KA6A 1YVHA 2JYQA 3S8LA 3UYOA 2MRJA 3IMJA 3VS7A 2CS0A 2YSXA 1O4FA 2H5KA 4XZ0A 2HDVA 2Y1NA 1TZEE 2GE9A 5BO4A 5AXIA 1O4DA 2H8HA 2L4KA 4GPLB 2DLZA 2CRHA 2C0OA 2Y1MA 4FL3A 3PQZA 3KFJA 3CBLA 1BHHB 4JEGA 1AB2A 1M61A 3OB1B 3PSKA 1FMKA 2MQIA 4M4ZA 4F5AA 1O4AA 1CWEA 2L6KA 3VS1A 1D4WA 1Y57A 1LUIA 2ETZA 5GJHA 1O47A 3PS5A 1YVLA 1BFIA 4K44A 1OO4A 4U1PA 1M27A 1FBVA 3MAZA 3PJPA 5DF6A 1CWDL 3ZNIA 4OHDA 1SPRA 5HKYA 1AYAA 4LUDA 1FU6A 3VS6A 1O4PA 5GJIA 2CR4A 1P13A 2C0TA 1O41A 1UUSA 2HCKA 2K79B 1HCTB 4P9VA 2C9WA 1A81A 3S8OA 3PSJA 2LNXA 1AOTF 4TZIA 4EIHA 4F5BA 3HCKA 1MILA 5I6VA 3PLFB 3BUOB 2DX0A 4EY0A 2QMSA 3CD3A 4DGPA 4E93A 1O4KA 1AYDA 2MK2A 3IN8A 1O44A 2SRCA 1LUMA 3EACA 3N7YA 1CSZA 1OO3A 1FBZA 1WQUA 1KC2A 2EO6A 4OHHA 1KSWA 5D0JA 1A1AA 2VIFA 4JGHA 2LCTA 3VS2A 1R1SA 2CI9A 3CXLA 2RORA 1D4TA 2RSYA 4P9ZA 1JYUA 2L3TA 5HKWA 1QADA 4OHIA 2RVFA 4OHLA 5AULA 3BUMB 3CWGA 4GL9E 1AD5A 2EKXA 2DLYA 2EO3A 2AOAA 3TKZA 5DC0B 5CDWA 2IZVA 5IBSA 1SKJA 5EEQA 3VS5A 2AUGA 1R1QA 1Y1UA 5KAZA 4K45A 1O43A 1IJRA 1FU5A 1R1PA 1A07A 3HIZB 3TL0A 2EYZA 3IN7A 2LQWA 1XA6A 1ZFPE 1RQQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O4Q A;  2XP1 A;  2FCI A;  1O42 A;  1SHD A;  3GXX A;  4QSY A;  1I3Z A;  1F1W A;  1TCE A;  1O46 A;  1X0N A;  1LCK A;  1MW4 A;  2HDX A;  3C7I A;  1RJA A;  3NHN A;  1AYC A;  1O4E A;  4K11 A;  3OV1 A;  2FO0 A;  4H1O A;  3VS3 A;  5EG3 B;  3IMD A;  1A1E A;  1BKL A;  3OP0 A;  1LUK A;  3VGO A;  1BHF A;  3VRQ A;  2EOB A;  4JE4 A;  1O4O A;  2CI8 A;  2DM0 A;  1SHB A;  3N84 A;  2OQ1 A;  1O4L A;  4XZ1 A;  1G83 A;  2ABL A;  2HMH A;  1A1B A;  5IBM A;  1O4B A;  1LKL A;  1IS0 A;  4OHE A;  1A09 A;  3QWX X;  2PNA A;  1BLJ A;  1NZV A;  2KNO A;  2EYV A;  4F59 A;  2CIA A;  4D8K A;  5EHR A;  1LKK A;  1X27 A;  1GHU A;  3VRP A;  3VRY A;  3WA4 A;  3VRN A;  1SPS A;  1PIC A;  4K2R A;  2EL8 A;  4GWF A;  3VRR A;  1BKM A;  3S9K A;  2K7A B;  1O4M A;  1JWO A;  3VS4 A;  3BUN B;  1OPK A;  1NRV A;  3VRZ A;  2YU7 A;  1GRI A;  2DCR A;  4L1B B;  1Z3K A;  2RMX A;  1H9O A;  1OPL A;  2Y3A B;  4FBN A;  3EAZ A;  1O49 A;  2EYY A;  1QG1 E;  1QCF A;  2H46 E;  5EHP A;  1BG1 A;  2IUI A;  2PLD A;  2PLE A;  1BF5 A;  2DVJ A;  1UUR A;  3S8N A;  1LCJ A;  1O4N A;  2SHP A;  3OB2 B;  3M7F A;  3PFV A;  1JYQ A;  4E68 A;  2IUG A;  1AYB A;  1O4R A;  3BKB A;  1O48 A;  1O4J A;  4ROJ A;  1CSY A;  4U17 A;  1X6C A;  3K2M A;  2OZO A;  3T04 A;  3MXC A;  4NWG A;  4X6S A;  2LQN A;  1NZL A;  3UF4 A;  3MXY A;  4LUE A;  1BLK A;  1SHA A;  1O45 A;  4FL2 A;  3US4 A;  1B47 A;  4NWF A;  3BUW B;  1F2F A;  3OVE A;  4A4B A;  2EU0 A;  1FYR A;  2MRK A;  3HHM B;  2PTK A;  5DC9 A;  2KK6 A;  5EEL A;  2HUW A;  1BFJ A;  1FHS A;  1O4C A;  5DC4 A;  1O4G A;  3QWY A;  1JU5 A;  2PNB A;  1LUN A;  2CBL A;  3GQI B;  1O4I A;  2IUH A;  1A1C A;  2BBU A;  1K9A A;  3VS0 A;  5HKZ A;  2B3O A;  5J3X A;  1A08 A;  1AOU F;  1D1Z A;  1HCS B;  3N8M A;  1CJ1 A;  2MC1 A;  1BM2 A;  2C0I A;  3GXW A;  1BHH A;  4A4C A;  4H34 A;  2LNW A;  2ECD A;  3VRO A;  1BMB A;  2GSB A;  1RPY A;  4DGX A;  3BUX B;  4WWQ A;  2AOB A;  1KA7 A;  1JYR A;  1O4H A;  1KA6 A;  1YVH A;  2JYQ A;  3S8L A;  3UYO A;  2MRJ A;  3IMJ A;  3VS7 A;  2CS0 A;  2YSX A;  1O4F A;  2H5K A;  4XZ0 A;  2HDV A;  2Y1N A;  1TZE E;  2GE9 A;  5BO4 A;  5AXI A;  1O4D A;  2H8H A;  2L4K A;  4GPL B;  2DLZ A;  2CRH A;  2C0O A;  2Y1M A;  4FL3 A;  3PQZ A;  3KFJ A;  3CBL A;  1BHH B;  4JEG A;  1AB2 A;  1M61 A;  3OB1 B;  3PSK A;  1FMK A;  2MQI A;  4M4Z A;  4F5A A;  1O4A A;  1CWE A;  2L6K A;  3VS1 A;  1D4W A;  1Y57 A;  1LUI A;  2ETZ A;  5GJH A;  1O47 A;  3PS5 A;  1YVL A;  1BFI A;  4K44 A;  1OO4 A;  4U1P A;  1M27 A;  1FBV A;  3MAZ A;  3PJP A;  5DF6 A;  1CWD L;  3ZNI A;  4OHD A;  1SPR A;  5HKY A;  1AYA A;  4LUD A;  1FU6 A;  3VS6 A;  1O4P A;  5GJI A;  2CR4 A;  1P13 A;  2C0T A;  1O41 A;  1UUS A;  2HCK A;  2K79 B;  1HCT B;  4P9V A;  2C9W A;  1A81 A;  3S8O A;  3PSJ A;  2LNX A;  1AOT F;  4TZI A;  4EIH A;  4F5B A;  3HCK A;  1MIL A;  5I6V A;  3PLF B;  3BUO B;  2DX0 A;  4EY0 A;  2QMS A;  3CD3 A;  4DGP A;  4E93 A;  1O4K A;  1AYD A;  2MK2 A;  3IN8 A;  1O44 A;  2SRC A;  1LUM A;  3EAC A;  3N7Y A;  1CSZ A;  1OO3 A;  1FBZ A;  1WQU A;  1KC2 A;  2EO6 A;  4OHH A;  1KSW A;  5D0J A;  1A1A A;  2VIF A;  4JGH A;  2LCT A;  3VS2 A;  1R1S A;  2CI9 A;  3CXL A;  2ROR A;  1D4T A;  2RSY A;  4P9Z A;  1JYU A;  2L3T A;  5HKW A;  1QAD A;  4OHI A;  2RVF A;  4OHL A;  5AUL A;  3BUM B;  3CWG A;  4GL9 E;  1AD5 A;  2EKX A;  2DLY A;  2EO3 A;  2AOA A;  3TKZ A;  5DC0 B;  5CDW A;  2IZV A;  5IBS A;  1SKJ A;  5EEQ A;  3VS5 A;  2AUG A;  1R1Q A;  1Y1U A;  5KAZ A;  4K45 A;  1O43 A;  1IJR A;  1FU5 A;  1R1P A;  1A07 A;  3HIZ B;  3TL0 A;  2EYZ A;  3IN7 A;  2LQW A;  1XA6 A;  1ZFP E;  1RQQ C; 
#chains in the Genus database with same CATH topology
 1O4Q A;  2XP1 A;  2FCI A;  1O42 A;  1SHD A;  3GXX A;  4QSY A;  1I3Z A;  1F1W A;  1TCE A;  1O46 A;  1X0N A;  1LCK A;  1MW4 A;  2HDX A;  3C7I A;  1RJA A;  3NHN A;  1AYC A;  1O4E A;  4K11 A;  3OV1 A;  2FO0 A;  4H1O A;  3VS3 A;  5EG3 B;  3IMD A;  3K2T A;  1A1E A;  1BKL A;  3OP0 A;  1LUK A;  3VGO A;  1BHF A;  3VRQ A;  2EOB A;  4JE4 A;  1O4O A;  2CI8 A;  2DM0 A;  1SHB A;  3N84 A;  2KGY A;  2OQ1 A;  1O4L A;  4XZ1 A;  1G83 A;  2ABL A;  2HMH A;  1A1B A;  5IBM A;  1O4B A;  1LKL A;  1IS0 A;  4OHE A;  1A09 A;  3QWX X;  2PNA A;  1BLJ A;  1NZV A;  2KNO A;  2EYV A;  4F59 A;  2CIA A;  4D8K A;  5EHR A;  1LKK A;  1X27 A;  1GHU A;  3VRP A;  3VRY A;  3WA4 A;  3VRN A;  1SPS A;  1PIC A;  4K2R A;  2EL8 A;  4GWF A;  3VRR A;  1BKM A;  3S9K A;  2K7A B;  1O4M A;  1JWO A;  3VS4 A;  3BUN B;  1OPK A;  1NRV A;  3VRZ A;  2YU7 A;  1GRI A;  2DCR A;  4L1B B;  1Z3K A;  2RMX A;  1H9O A;  1OPL A;  2Y3A B;  4FBN A;  3EAZ A;  1O49 A;  2EYY A;  1QG1 E;  1QCF A;  2H46 E;  5EHP A;  1BG1 A;  2IUI A;  2PLD A;  2PLE A;  1BF5 A;  2DVJ A;  1UUR A;  3S8N A;  1LCJ A;  1O4N A;  2SHP A;  3OB2 B;  3M7F A;  3PFV A;  1JYQ A;  4E68 A;  2IUG A;  1AYB A;  1O4R A;  3BKB A;  1O48 A;  1O4J A;  4ROJ A;  1CSY A;  4U17 A;  1X6C A;  3K2M A;  2OZO A;  3T04 A;  3MXC A;  4NWG A;  4X6S A;  2LQN A;  1NZL A;  3UF4 A;  3MXY A;  4LUE A;  1BLK A;  1SHA A;  1O45 A;  4FL2 A;  3US4 A;  1B47 A;  4NWF A;  3BUW B;  1F2F A;  3OVE A;  4A4B A;  2EU0 A;  1FYR A;  2MRK A;  3HHM B;  2PTK A;  5DC9 A;  2KK6 A;  5EEL A;  2HUW A;  1BFJ A;  1FHS A;  1O4C A;  5DC4 A;  1O4G A;  3QWY A;  1JU5 A;  2PNB A;  1LUN A;  2CBL A;  3GQI B;  1O4I A;  2IUH A;  1A1C A;  2BBU A;  1K9A A;  3VS0 A;  5HKZ A;  2B3O A;  5J3X A;  1A08 A;  1AOU F;  1D1Z A;  1HCS B;  3N8M A;  1CJ1 A;  2MC1 A;  1BM2 A;  2C0I A;  3GXW A;  1BHH A;  4A4C A;  4H34 A;  2LNW A;  2ECD A;  3LYV A;  3VRO A;  1BMB A;  2GSB A;  1RPY A;  4DGX A;  3BUX B;  4WWQ A;  2AOB A;  1KA7 A;  1JYR A;  1O4H A;  1KA6 A;  1YVH A;  2JYQ A;  3S8L A;  3UYO A;  2MRJ A;  3IMJ A;  3VS7 A;  2CS0 A;  2YSX A;  1O4F A;  2H5K A;  4XZ0 A;  2HDV A;  2Y1N A;  1TZE E;  2GE9 A;  5BO4 A;  5AXI A;  1O4D A;  2H8H A;  2L4K A;  4GPL B;  2DLZ A;  2CRH A;  2C0O A;  2Y1M A;  4FL3 A;  3PQZ A;  3KFJ A;  3CBL A;  1BHH B;  4JEG A;  1AB2 A;  1M61 A;  3OB1 B;  3PSK A;  1FMK A;  2MQI A;  4M4Z A;  4F5A A;  1O4A A;  1CWE A;  2L6K A;  3VS1 A;  1D4W A;  1Y57 A;  1LUI A;  2ETZ A;  5GJH A;  1O47 A;  3PS5 A;  1YVL A;  1BFI A;  4K44 A;  1OO4 A;  4U1P A;  1M27 A;  1FBV A;  3MAZ A;  3PJP A;  5DF6 A;  1CWD L;  3ZNI A;  4OHD A;  1SPR A;  5HKY A;  1AYA A;  4LUD A;  1FU6 A;  3VS6 A;  1O4P A;  5GJI A;  2CR4 A;  1P13 A;  2C0T A;  1O41 A;  1UUS A;  2HCK A;  2K79 B;  1HCT B;  4P9V A;  2C9W A;  1A81 A;  3S8O A;  3PSJ A;  2LNX A;  1AOT F;  4TZI A;  4EIH A;  4F5B A;  3HCK A;  1MIL A;  5I6V A;  3PLF B;  3BUO B;  2DX0 A;  4EY0 A;  2QMS A;  3CD3 A;  4DGP A;  4E93 A;  1O4K A;  1AYD A;  2MK2 A;  3IN8 A;  1O44 A;  2SRC A;  1LUM A;  3EAC A;  3N7Y A;  1CSZ A;  1OO3 A;  1FBZ A;  1WQU A;  1KC2 A;  2EO6 A;  4OHH A;  1KSW A;  5D0J A;  1A1A A;  2VIF A;  4JGH A;  2LCT A;  3VS2 A;  1R1S A;  2CI9 A;  3CXL A;  2ROR A;  1D4T A;  2RSY A;  4P9Z A;  1JYU A;  2L3T A;  5HKW A;  1QAD A;  4OHI A;  2RVF A;  4OHL A;  5AUL A;  3BUM B;  3CWG A;  4GL9 E;  1AD5 A;  2EKX A;  2DLY A;  2EO3 A;  2AOA A;  3TKZ A;  5DC0 B;  5CDW A;  2IZV A;  5IBS A;  1SKJ A;  5EEQ A;  3VS5 A;  2AUG A;  2LRA A;  1R1Q A;  1Y1U A;  5KAZ A;  4K45 A;  1O43 A;  1IJR A;  1FU5 A;  1R1P A;  1A07 A;  3HIZ B;  3TL0 A;  2EYZ A;  3IN7 A;  2LQW A;  1XA6 A;  1ZFP E;  1RQQ C; 
#chains in the Genus database with same CATH homology
 1O4Q A;  2XP1 A;  2FCI A;  1O42 A;  1SHD A;  3GXX A;  4QSY A;  1I3Z A;  1F1W A;  1TCE A;  1O46 A;  1X0N A;  1LCK A;  1MW4 A;  2HDX A;  3C7I A;  1RJA A;  3NHN A;  1AYC A;  1O4E A;  4K11 A;  3OV1 A;  2FO0 A;  4H1O A;  3VS3 A;  5EG3 B;  3IMD A;  1A1E A;  1BKL A;  3OP0 A;  1LUK A;  3VGO A;  1BHF A;  3VRQ A;  2EOB A;  4JE4 A;  1O4O A;  2CI8 A;  2DM0 A;  1SHB A;  3N84 A;  2OQ1 A;  1O4L A;  4XZ1 A;  1G83 A;  2ABL A;  2HMH A;  1A1B A;  5IBM A;  1O4B A;  1LKL A;  1IS0 A;  4OHE A;  1A09 A;  3QWX X;  2PNA A;  1BLJ A;  1NZV A;  2KNO A;  2EYV A;  4F59 A;  2CIA A;  4D8K A;  5EHR A;  1LKK A;  1X27 A;  1GHU A;  3VRP A;  3VRY A;  3WA4 A;  3VRN A;  1SPS A;  1PIC A;  4K2R A;  2EL8 A;  4GWF A;  3VRR A;  1BKM A;  3S9K A;  2K7A B;  1O4M A;  1JWO A;  3VS4 A;  3BUN B;  1OPK A;  1NRV A;  3VRZ A;  2YU7 A;  1GRI A;  2DCR A;  4L1B B;  1Z3K A;  2RMX A;  1H9O A;  1OPL A;  2Y3A B;  4FBN A;  3EAZ A;  1O49 A;  2EYY A;  1QG1 E;  1QCF A;  2H46 E;  5EHP A;  1BG1 A;  2IUI A;  2PLD A;  2PLE A;  1BF5 A;  2DVJ A;  1UUR A;  3S8N A;  1LCJ A;  1O4N A;  2SHP A;  3OB2 B;  3M7F A;  3PFV A;  1JYQ A;  4E68 A;  2IUG A;  1AYB A;  1O4R A;  3BKB A;  1O48 A;  1O4J A;  4ROJ A;  1CSY A;  4U17 A;  1X6C A;  3K2M A;  2OZO A;  3T04 A;  3MXC A;  4NWG A;  4X6S A;  2LQN A;  1NZL A;  3UF4 A;  3MXY A;  4LUE A;  1BLK A;  1SHA A;  1O45 A;  4FL2 A;  3US4 A;  1B47 A;  4NWF A;  3BUW B;  1F2F A;  3OVE A;  4A4B A;  2EU0 A;  1FYR A;  2MRK A;  3HHM B;  2PTK A;  5DC9 A;  2KK6 A;  5EEL A;  2HUW A;  1BFJ A;  1FHS A;  1O4C A;  5DC4 A;  1O4G A;  3QWY A;  1JU5 A;  2PNB A;  1LUN A;  2CBL A;  3GQI B;  1O4I A;  2IUH A;  1A1C A;  2BBU A;  1K9A A;  3VS0 A;  5HKZ A;  2B3O A;  5J3X A;  1A08 A;  1AOU F;  1D1Z A;  1HCS B;  3N8M A;  1CJ1 A;  2MC1 A;  1BM2 A;  2C0I A;  3GXW A;  1BHH A;  4A4C A;  4H34 A;  2LNW A;  2ECD A;  3VRO A;  1BMB A;  2GSB A;  1RPY A;  4DGX A;  3BUX B;  4WWQ A;  2AOB A;  1KA7 A;  1JYR A;  1O4H A;  1KA6 A;  1YVH A;  2JYQ A;  3S8L A;  3UYO A;  2MRJ A;  3IMJ A;  3VS7 A;  2CS0 A;  2YSX A;  1O4F A;  2H5K A;  4XZ0 A;  2HDV A;  2Y1N A;  1TZE E;  2GE9 A;  5BO4 A;  5AXI A;  1O4D A;  2H8H A;  2L4K A;  4GPL B;  2DLZ A;  2CRH A;  2C0O A;  2Y1M A;  4FL3 A;  3PQZ A;  3KFJ A;  3CBL A;  1BHH B;  4JEG A;  1AB2 A;  1M61 A;  3OB1 B;  3PSK A;  1FMK A;  2MQI A;  4M4Z A;  4F5A A;  1O4A A;  1CWE A;  2L6K A;  3VS1 A;  1D4W A;  1Y57 A;  1LUI A;  2ETZ A;  5GJH A;  1O47 A;  3PS5 A;  1YVL A;  1BFI A;  4K44 A;  1OO4 A;  4U1P A;  1M27 A;  1FBV A;  3MAZ A;  3PJP A;  5DF6 A;  1CWD L;  3ZNI A;  4OHD A;  1SPR A;  5HKY A;  1AYA A;  4LUD A;  1FU6 A;  3VS6 A;  1O4P A;  5GJI A;  2CR4 A;  1P13 A;  2C0T A;  1O41 A;  1UUS A;  2HCK A;  2K79 B;  1HCT B;  4P9V A;  2C9W A;  1A81 A;  3S8O A;  3PSJ A;  2LNX A;  1AOT F;  4TZI A;  4EIH A;  4F5B A;  3HCK A;  1MIL A;  5I6V A;  3PLF B;  3BUO B;  2DX0 A;  4EY0 A;  2QMS A;  3CD3 A;  4DGP A;  4E93 A;  1O4K A;  1AYD A;  2MK2 A;  3IN8 A;  1O44 A;  2SRC A;  1LUM A;  3EAC A;  3N7Y A;  1CSZ A;  1OO3 A;  1FBZ A;  1WQU A;  1KC2 A;  2EO6 A;  4OHH A;  1KSW A;  5D0J A;  1A1A A;  2VIF A;  4JGH A;  2LCT A;  3VS2 A;  1R1S A;  2CI9 A;  3CXL A;  2ROR A;  1D4T A;  2RSY A;  4P9Z A;  1JYU A;  2L3T A;  5HKW A;  1QAD A;  4OHI A;  2RVF A;  4OHL A;  5AUL A;  3BUM B;  3CWG A;  4GL9 E;  1AD5 A;  2EKX A;  2DLY A;  2EO3 A;  2AOA A;  3TKZ A;  5DC0 B;  5CDW A;  2IZV A;  5IBS A;  1SKJ A;  5EEQ A;  3VS5 A;  2AUG A;  1R1Q A;  1Y1U A;  5KAZ A;  4K45 A;  1O43 A;  1IJR A;  1FU5 A;  1R1P A;  1A07 A;  3HIZ B;  3TL0 A;  2EYZ A;  3IN7 A;  2LQW A;  1XA6 A;  1ZFP E;  1RQQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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