1SPSA

Binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
103
structure length
103
Chain Sequence
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
pubmed doi rcsb
molecule tags Transferase(phosphotransferase)
source organism Rous sarcoma virus
molecule keywords SRC SH2 DOMAIN
total genus 27
structure length 103
sequence length 103
chains with identical sequence B, C
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1993-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1spsA00
1I3ZA 2SRCA 2EYZA 2MQIA 4GWFA 2EOBA 2IUHA 5DC9A 2RMXA 2IUIA 5BO4A 1RQQC 3ZNIA 5EELA 5HKWA 4H34A 3CXLA 3IN8A 5DF6A 2CBLA 2QMSA 2PNBA 3UF4A 1H9OA 2YU7A 1BLJA 3HIZB 3S8NA 4EY0A 1BLKA 2AOAA 4L1BB 3TL0A 1AYBA 1Y57A 1O4LA 5I6VA 3OB1B 1KSWA 2SHPA 4NWFA 4F59A 1BHHB 2LNXA 3VS2A 2MK2A 3GXWA 1O4NA 2IUGA 2AUGA 1CJ1A 3UYOA 1BM2A 4GL9E 4EIHA 1Z3KA 4D8KA 2EL8A 1F2FA 3OB2B 5HKYA 1LKKA 2HMHA 3MXYA 1FYRA 1LUKA 1LCKA 1OPKA 3PFVA 2DVJA 2DCRA 1KA7A 1LUNA 5KAZA 1A1BA 1YVLA 1KC2A 2JYQA 4U17A 1NZVA 2OQ1A 1SPRA 2RSYA 2LQNA 1TCEA 4OHDA 5EEQA 1XA6A 2K7AB 2DM0A 1O4CA 4K44A 5DC4A 1GHUA 1GRIA 3VS0A 4U1PA 2H46E 1AOTF 2FO0A 2L3TA 5J3XA 2Y1MA 2ECDA 2BBUA 3KFJA 2H8HA 3NHNA 1CSYA 5EHRA 4K11A 5AULA 1O4JA 1FBZA 1O4AA 1A08A 2EO3A 1O4PA 3PJPA 3PLFB 5HKZA 5EHPA 2B3OA 2AOBA 3PQZA 1RJAA 2ETZA 1D4TA 3VRZA 4DGXA 1QADA 2HDXA 3OVEA 2HUWA 2CS0A 3VS6A 1SKJA 1LUIA 3N84A 5EG3B 1YVHA 3MAZA 1A07A 3M7FA 1D1ZA 5CDWA 1O4OA 1FMKA 3VS5A 2L6KA 1BF5A 3CD3A 3US4A 2PNAA 4FBNA 3PS5A 2YSXA 3S8LA 1R1QA 2EYYA 2RVFA 1KA6A 3BUNB 2CIAA 4NWGA 2LNWA 2OZOA 1O47A 4FL2A 3OV1A 2C0IA 2GSBA 1O41A 1FHSA 4GPLB 2PLDA 4XZ0A 1X6CA 4E93A 1JYUA 3T04A 1OPLA 2PLEA 2DLYA 3QWYA 1ZFPE 2KK6A 1O4FA 1SPSA 5GJHA 1O44A 3IMJA 1JWOA 1JYRA 1QCFA 2CI8A 1A81A 1O49A 2KNOA 4WWQA 4H1OA 1M61A 1LCJA 2MC1A 2VIFA 1A1EA 3BUOB 4A4CA 3S8OA 4F5BA 2EYVA 2ABLA 2XP1A 1RPYA 2LCTA 2EU0A 1CWEA 1A1AA 3VRPA 1QG1E 1O4IA 3TKZA 1HCTB 1FU5A 2MRKA 1O43A 4FL3A 4K45A 3CWGA 3VRQA 1BKMA 1FBVA 1CWDL 1IS0A 2CRHA 3VRNA 3IMDA 4K2RA 1R1PA 1LKLA 1BHHA 1K9AA 1LUMA 1D4WA 4LUEA 4M4ZA 1M27A 3QWXX 3C7IA 1UURA 2EKXA 1X27A 1PICA 4P9ZA 2DX0A 1P13A 3EAZA 4OHIA 3EACA 4OHLA 1AYDA 3BUWB 1AD5A 4OHHA 1A09A 3BUMB 1SHDA 2C0OA 3VS7A 3S9KA 4XZ1A 2CI9A 1O4BA 4P9VA 3MXCA 2HDVA 1Y1UA 5IBMA 2LQWA 2C9WA 1JU5A 2RORA 3VGOA 5DC0B 3GXXA 1AOUF 1O4RA 1F1WA 4A4BA 3BUXB 3VS3A 1BFIA 4TZIA 1A1CA 5IBSA 1AYAA 1BKLA 4DGPA 3N8MA 1IJRA 3CBLA 1B47A 3BKBA 1R1SA 1O4GA 1O46A 1O4EA 1WQUA 2PTKA 1G83A 2Y3AB 1FU6A 1SHAA 4X6SA 3VS1A 1NRVA 1O45A 3N7YA 1O4KA 1AYCA 1BFJA 3PSKA 3VRRA 1HCSB 1UUSA 2MRJA 3IN7A 1O4MA 3HCKA 1BMBA 2DLZA 2EO6A 4QSYA 1SHBA 1MILA 1O4QA 3VS4A 2H5KA 2CR4A 2C0TA 2FCIA 3OP0A 1X0NA 5D0JA 1OO3A 3VRYA 1O42A 2HCKA 1O4HA 4LUDA 4E68A 4OHEA 4F5AA 4JE4A 3K2MA 3GQIB 1TZEE 4ROJA 5AXIA 1CSZA 1JYQA 2Y1NA 2IZVA 1BHFA 2K79B 2GE9A 1OO4A 4JGHA 5GJIA 1AB2A 3HHMB 3WA4A 1O48A 4JEGA 1NZLA 3VROA 1O4DA 1MW4A 3PSJA 2L4KA 1BG1A
chains in the Genus database with same CATH superfamily
1I3ZA 2SRCA 2EYZA 2MQIA 4GWFA 2EOBA 2IUHA 5DC9A 2RMXA 2IUIA 5BO4A 1RQQC 3ZNIA 5EELA 5HKWA 4H34A 3CXLA 3IN8A 5DF6A 2CBLA 2QMSA 2PNBA 3UF4A 1H9OA 2YU7A 1BLJA 3HIZB 3S8NA 4EY0A 1BLKA 2AOAA 4L1BB 3TL0A 1AYBA 1Y57A 1O4LA 5I6VA 3OB1B 1KSWA 2SHPA 4NWFA 4F59A 1BHHB 2LNXA 3VS2A 2MK2A 3GXWA 1O4NA 2IUGA 2AUGA 1CJ1A 3UYOA 1BM2A 4GL9E 4EIHA 1Z3KA 4D8KA 2EL8A 1F2FA 3OB2B 5HKYA 1LKKA 2HMHA 3MXYA 1FYRA 1LUKA 1LCKA 1OPKA 3PFVA 2DVJA 2DCRA 1KA7A 1LUNA 5KAZA 1A1BA 1YVLA 1KC2A 2JYQA 4U17A 1NZVA 2OQ1A 1SPRA 2RSYA 2LQNA 1TCEA 4OHDA 5EEQA 1XA6A 2K7AB 2DM0A 1O4CA 4K44A 5DC4A 1GHUA 1GRIA 3VS0A 4U1PA 2H46E 1AOTF 2FO0A 2L3TA 5J3XA 2Y1MA 2ECDA 2BBUA 3KFJA 2H8HA 3NHNA 1CSYA 5EHRA 4K11A 5AULA 1O4JA 1FBZA 1O4AA 1A08A 2EO3A 1O4PA 3PJPA 3PLFB 5HKZA 5EHPA 2B3OA 2AOBA 3PQZA 1RJAA 2ETZA 1D4TA 3VRZA 4DGXA 1QADA 2HDXA 3OVEA 2HUWA 2CS0A 3VS6A 1SKJA 1LUIA 3N84A 5EG3B 1YVHA 3MAZA 1A07A 3M7FA 1D1ZA 5CDWA 1O4OA 1FMKA 3VS5A 2L6KA 1BF5A 3CD3A 3US4A 2PNAA 4FBNA 3PS5A 2YSXA 3S8LA 1R1QA 2EYYA 2RVFA 1KA6A 3BUNB 2CIAA 4NWGA 2LNWA 2OZOA 1O47A 4FL2A 3OV1A 2C0IA 2GSBA 1O41A 1FHSA 4GPLB 2PLDA 4XZ0A 1X6CA 4E93A 1JYUA 3T04A 1OPLA 2PLEA 2DLYA 3QWYA 1ZFPE 2KK6A 1O4FA 1SPSA 5GJHA 1O44A 3IMJA 1JWOA 1JYRA 1QCFA 2CI8A 1A81A 1O49A 3LYVA 2KNOA 4WWQA 4H1OA 1M61A 1LCJA 2MC1A 2VIFA 1A1EA 3BUOB 4A4CA 3S8OA 4F5BA 2EYVA 2ABLA 2XP1A 1RPYA 2LCTA 2EU0A 1CWEA 1A1AA 3VRPA 1QG1E 1O4IA 3TKZA 1HCTB 1FU5A 2MRKA 1O43A 4FL3A 4K45A 3CWGA 2LRAA 3VRQA 1BKMA 1FBVA 1CWDL 1IS0A 2CRHA 3VRNA 3IMDA 4K2RA 1R1PA 1LKLA 1BHHA 1K9AA 1LUMA 1D4WA 4LUEA 4M4ZA 1M27A 3QWXX 2KGYA 3C7IA 1UURA 2EKXA 1X27A 1PICA 4P9ZA 2DX0A 1P13A 3EAZA 4OHIA 3EACA 4OHLA 1AYDA 3BUWB 1AD5A 4OHHA 1A09A 3BUMB 1SHDA 2C0OA 3VS7A 3S9KA 4XZ1A 2CI9A 1O4BA 4P9VA 3MXCA 2HDVA 1Y1UA 5IBMA 2LQWA 2C9WA 1JU5A 2RORA 3VGOA 5DC0B 3GXXA 1AOUF 1O4RA 1F1WA 4A4BA 3BUXB 3VS3A 1BFIA 4TZIA 1A1CA 5IBSA 1AYAA 1BKLA 4DGPA 3N8MA 1IJRA 3CBLA 1B47A 3BKBA 1R1SA 1O4GA 1O46A 1O4EA 1WQUA 2PTKA 1G83A 2Y3AB 1FU6A 1SHAA 4X6SA 3VS1A 1NRVA 1O45A 3N7YA 1O4KA 1AYCA 1BFJA 3PSKA 3VRRA 1HCSB 1UUSA 2MRJA 3IN7A 1O4MA 3HCKA 1BMBA 2DLZA 2EO6A 4QSYA 1SHBA 1MILA 1O4QA 3VS4A 2H5KA 2CR4A 2C0TA 2FCIA 3OP0A 1X0NA 5D0JA 1OO3A 3VRYA 1O42A 2HCKA 1O4HA 4LUDA 4E68A 4OHEA 4F5AA 4JE4A 3K2MA 3GQIB 1TZEE 4ROJA 5AXIA 1CSZA 1JYQA 2Y1NA 2IZVA 1BHFA 2K79B 3K2TA 2GE9A 1OO4A 4JGHA 5GJIA 1AB2A 3HHMB 3WA4A 1O48A 4JEGA 1NZLA 3VROA 1O4DA 1MW4A 3PSJA 2L4KA 1BG1A
chains in the Genus database with same CATH topology
1I3ZA 2SRCA 2EYZA 2MQIA 4GWFA 2EOBA 2IUHA 5DC9A 2RMXA 2IUIA 5BO4A 1RQQC 3ZNIA 5EELA 5HKWA 4H34A 3CXLA 3IN8A 5DF6A 2CBLA 2QMSA 2PNBA 3UF4A 1H9OA 2YU7A 1BLJA 3HIZB 3S8NA 4EY0A 1BLKA 2AOAA 4L1BB 3TL0A 1AYBA 1Y57A 1O4LA 5I6VA 3OB1B 1KSWA 2SHPA 4NWFA 4F59A 1BHHB 2LNXA 3VS2A 2MK2A 3GXWA 1O4NA 2IUGA 2AUGA 1CJ1A 3UYOA 1BM2A 4GL9E 4EIHA 1Z3KA 4D8KA 2EL8A 1F2FA 3OB2B 5HKYA 1LKKA 2HMHA 3MXYA 1FYRA 1LUKA 1LCKA 1OPKA 3PFVA 2DVJA 2DCRA 1KA7A 1LUNA 5KAZA 1A1BA 1YVLA 1KC2A 2JYQA 4U17A 1NZVA 2OQ1A 1SPRA 2RSYA 2LQNA 1TCEA 4OHDA 5EEQA 1XA6A 2K7AB 2DM0A 1O4CA 4K44A 5DC4A 1GHUA 1GRIA 3VS0A 4U1PA 2H46E 1AOTF 2FO0A 2L3TA 5J3XA 2Y1MA 2ECDA 2BBUA 3KFJA 2H8HA 3NHNA 1CSYA 5EHRA 4K11A 5AULA 1O4JA 1FBZA 1O4AA 1A08A 2EO3A 1O4PA 3PJPA 3PLFB 5HKZA 5EHPA 2B3OA 2AOBA 3PQZA 1RJAA 2ETZA 1D4TA 3VRZA 4DGXA 1QADA 2HDXA 3OVEA 2HUWA 2CS0A 3VS6A 1SKJA 1LUIA 3N84A 5EG3B 1YVHA 3MAZA 1A07A 3M7FA 1D1ZA 5CDWA 1O4OA 1FMKA 3VS5A 2L6KA 1BF5A 3CD3A 3US4A 2PNAA 4FBNA 3PS5A 2YSXA 3S8LA 1R1QA 2EYYA 2RVFA 1KA6A 3BUNB 2CIAA 4NWGA 2LNWA 2OZOA 1O47A 4FL2A 3OV1A 2C0IA 2GSBA 1O41A 1FHSA 4GPLB 2PLDA 4XZ0A 1X6CA 4E93A 1JYUA 3T04A 1OPLA 2PLEA 2DLYA 3QWYA 1ZFPE 2KK6A 1O4FA 1SPSA 5GJHA 1O44A 3IMJA 1JWOA 1JYRA 1QCFA 2CI8A 1A81A 1O49A 2KNOA 4WWQA 4H1OA 1M61A 1LCJA 2MC1A 2VIFA 1A1EA 3BUOB 4A4CA 3S8OA 4F5BA 2EYVA 2ABLA 2XP1A 1RPYA 2LCTA 2EU0A 1CWEA 1A1AA 3VRPA 1QG1E 1O4IA 3TKZA 1HCTB 1FU5A 2MRKA 1O43A 4FL3A 4K45A 3CWGA 3VRQA 1BKMA 1FBVA 1CWDL 1IS0A 2CRHA 3VRNA 3IMDA 4K2RA 1R1PA 1LKLA 1BHHA 1K9AA 1LUMA 1D4WA 4LUEA 4M4ZA 1M27A 3QWXX 3C7IA 1UURA 2EKXA 1X27A 1PICA 4P9ZA 2DX0A 1P13A 3EAZA 4OHIA 3EACA 4OHLA 1AYDA 3BUWB 1AD5A 4OHHA 1A09A 3BUMB 1SHDA 2C0OA 3VS7A 3S9KA 4XZ1A 2CI9A 1O4BA 4P9VA 3MXCA 2HDVA 1Y1UA 5IBMA 2LQWA 2C9WA 1JU5A 2RORA 3VGOA 5DC0B 3GXXA 1AOUF 1O4RA 1F1WA 4A4BA 3BUXB 3VS3A 1BFIA 4TZIA 1A1CA 5IBSA 1AYAA 1BKLA 4DGPA 3N8MA 1IJRA 3CBLA 1B47A 3BKBA 1R1SA 1O4GA 1O46A 1O4EA 1WQUA 2PTKA 1G83A 2Y3AB 1FU6A 1SHAA 4X6SA 3VS1A 1NRVA 1O45A 3N7YA 1O4KA 1AYCA 1BFJA 3PSKA 3VRRA 1HCSB 1UUSA 2MRJA 3IN7A 1O4MA 3HCKA 1BMBA 2DLZA 2EO6A 4QSYA 1SHBA 1MILA 1O4QA 3VS4A 2H5KA 2CR4A 2C0TA 2FCIA 3OP0A 1X0NA 5D0JA 1OO3A 3VRYA 1O42A 2HCKA 1O4HA 4LUDA 4E68A 4OHEA 4F5AA 4JE4A 3K2MA 3GQIB 1TZEE 4ROJA 5AXIA 1CSZA 1JYQA 2Y1NA 2IZVA 1BHFA 2K79B 2GE9A 1OO4A 4JGHA 5GJIA 1AB2A 3HHMB 3WA4A 1O48A 4JEGA 1NZLA 3VROA 1O4DA 1MW4A 3PSJA 2L4KA 1BG1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I3Z A;  2SRC A;  2EYZ A;  2MQI A;  4GWF A;  2EOB A;  2IUH A;  5DC9 A;  2RMX A;  2IUI A;  5BO4 A;  1RQQ C;  3ZNI A;  5EEL A;  5HKW A;  4H34 A;  3CXL A;  3IN8 A;  5DF6 A;  2CBL A;  2QMS A;  2PNB A;  3UF4 A;  1H9O A;  2YU7 A;  1BLJ A;  3HIZ B;  3S8N A;  4EY0 A;  1BLK A;  2AOA A;  4L1B B;  3TL0 A;  1AYB A;  1Y57 A;  1O4L A;  5I6V A;  3OB1 B;  1KSW A;  2SHP A;  4NWF A;  4F59 A;  1BHH B;  2LNX A;  3VS2 A;  2MK2 A;  3GXW A;  1O4N A;  2IUG A;  2AUG A;  1CJ1 A;  3UYO A;  1BM2 A;  4GL9 E;  4EIH A;  1Z3K A;  4D8K A;  2EL8 A;  1F2F A;  3OB2 B;  5HKY A;  1LKK A;  2HMH A;  3MXY A;  1FYR A;  1LUK A;  1LCK A;  1OPK A;  3PFV A;  2DVJ A;  2DCR A;  1KA7 A;  1LUN A;  5KAZ A;  1A1B A;  1YVL A;  1KC2 A;  2JYQ A;  4U17 A;  1NZV A;  2OQ1 A;  1SPR A;  2RSY A;  2LQN A;  1TCE A;  4OHD A;  5EEQ A;  1XA6 A;  2K7A B;  2DM0 A;  1O4C A;  4K44 A;  5DC4 A;  1GHU A;  1GRI A;  3VS0 A;  4U1P A;  2H46 E;  1AOT F;  2FO0 A;  2L3T A;  5J3X A;  2Y1M A;  2ECD A;  2BBU A;  3KFJ A;  2H8H A;  3NHN A;  1CSY A;  5EHR A;  4K11 A;  5AUL A;  1O4J A;  1FBZ A;  1O4A A;  1A08 A;  2EO3 A;  1O4P A;  3PJP A;  3PLF B;  5HKZ A;  5EHP A;  2B3O A;  2AOB A;  3PQZ A;  1RJA A;  2ETZ A;  1D4T A;  3VRZ A;  4DGX A;  1QAD A;  2HDX A;  3OVE A;  2HUW A;  2CS0 A;  3VS6 A;  1SKJ A;  1LUI A;  3N84 A;  5EG3 B;  1YVH A;  3MAZ A;  1A07 A;  3M7F A;  1D1Z A;  5CDW A;  1O4O A;  1FMK A;  3VS5 A;  2L6K A;  1BF5 A;  3CD3 A;  3US4 A;  2PNA A;  4FBN A;  3PS5 A;  2YSX A;  3S8L A;  1R1Q A;  2EYY A;  2RVF A;  1KA6 A;  3BUN B;  2CIA A;  4NWG A;  2LNW A;  2OZO A;  1O47 A;  4FL2 A;  3OV1 A;  2C0I A;  2GSB A;  1O41 A;  1FHS A;  4GPL B;  2PLD A;  4XZ0 A;  1X6C A;  4E93 A;  1JYU A;  3T04 A;  1OPL A;  2PLE A;  2DLY A;  3QWY A;  1ZFP E;  2KK6 A;  1O4F A;  1SPS A;  5GJH A;  1O44 A;  3IMJ A;  1JWO A;  1JYR A;  1QCF A;  2CI8 A;  1A81 A;  1O49 A;  2KNO A;  4WWQ A;  4H1O A;  1M61 A;  1LCJ A;  2MC1 A;  2VIF A;  1A1E A;  3BUO B;  4A4C A;  3S8O A;  4F5B A;  2EYV A;  2ABL A;  2XP1 A;  1RPY A;  2LCT A;  2EU0 A;  1CWE A;  1A1A A;  3VRP A;  1QG1 E;  1O4I A;  3TKZ A;  1HCT B;  1FU5 A;  2MRK A;  1O43 A;  4FL3 A;  4K45 A;  3CWG A;  3VRQ A;  1BKM A;  1FBV A;  1CWD L;  1IS0 A;  2CRH A;  3VRN A;  3IMD A;  4K2R A;  1R1P A;  1LKL A;  1BHH A;  1K9A A;  1LUM A;  1D4W A;  4LUE A;  4M4Z A;  1M27 A;  3QWX X;  3C7I A;  1UUR A;  2EKX A;  1X27 A;  1PIC A;  4P9Z A;  2DX0 A;  1P13 A;  3EAZ A;  4OHI A;  3EAC A;  4OHL A;  1AYD A;  3BUW B;  1AD5 A;  4OHH A;  1A09 A;  3BUM B;  1SHD A;  2C0O A;  3VS7 A;  3S9K A;  4XZ1 A;  2CI9 A;  1O4B A;  4P9V A;  3MXC A;  2HDV A;  1Y1U A;  5IBM A;  2LQW A;  2C9W A;  1JU5 A;  2ROR A;  3VGO A;  5DC0 B;  3GXX A;  1AOU F;  1O4R A;  1F1W A;  4A4B A;  3BUX B;  3VS3 A;  1BFI A;  4TZI A;  1A1C A;  5IBS A;  1AYA A;  1BKL A;  4DGP A;  3N8M A;  1IJR A;  3CBL A;  1B47 A;  3BKB A;  1R1S A;  1O4G A;  1O46 A;  1O4E A;  1WQU A;  2PTK A;  1G83 A;  2Y3A B;  1FU6 A;  1SHA A;  4X6S A;  3VS1 A;  1NRV A;  1O45 A;  3N7Y A;  1O4K A;  1AYC A;  1BFJ A;  3PSK A;  3VRR A;  1HCS B;  1UUS A;  2MRJ A;  3IN7 A;  1O4M A;  3HCK A;  1BMB A;  2DLZ A;  2EO6 A;  4QSY A;  1SHB A;  1MIL A;  1O4Q A;  3VS4 A;  2H5K A;  2CR4 A;  2C0T A;  2FCI A;  3OP0 A;  1X0N A;  5D0J A;  1OO3 A;  3VRY A;  1O42 A;  2HCK A;  1O4H A;  4LUD A;  4E68 A;  4OHE A;  4F5A A;  4JE4 A;  3K2M A;  3GQI B;  1TZE E;  4ROJ A;  5AXI A;  1CSZ A;  1JYQ A;  2Y1N A;  2IZV A;  1BHF A;  2K79 B;  2GE9 A;  1OO4 A;  4JGH A;  5GJI A;  1AB2 A;  3HHM B;  3WA4 A;  1O48 A;  4JEG A;  1NZL A;  3VRO A;  1O4D A;  1MW4 A;  3PSJ A;  2L4K A;  1BG1 A; 
#chains in the Genus database with same CATH topology
 1I3Z A;  2SRC A;  2EYZ A;  2MQI A;  4GWF A;  2EOB A;  2IUH A;  5DC9 A;  2RMX A;  2IUI A;  5BO4 A;  1RQQ C;  3ZNI A;  5EEL A;  5HKW A;  4H34 A;  3CXL A;  3IN8 A;  5DF6 A;  2CBL A;  2QMS A;  2PNB A;  3UF4 A;  1H9O A;  2YU7 A;  1BLJ A;  3HIZ B;  3S8N A;  4EY0 A;  1BLK A;  2AOA A;  4L1B B;  3TL0 A;  1AYB A;  1Y57 A;  1O4L A;  5I6V A;  3OB1 B;  1KSW A;  2SHP A;  4NWF A;  4F59 A;  1BHH B;  2LNX A;  3VS2 A;  2MK2 A;  3GXW A;  1O4N A;  2IUG A;  2AUG A;  1CJ1 A;  3UYO A;  1BM2 A;  4GL9 E;  4EIH A;  1Z3K A;  4D8K A;  2EL8 A;  1F2F A;  3OB2 B;  5HKY A;  1LKK A;  2HMH A;  3MXY A;  1FYR A;  1LUK A;  1LCK A;  1OPK A;  3PFV A;  2DVJ A;  2DCR A;  1KA7 A;  1LUN A;  5KAZ A;  1A1B A;  1YVL A;  1KC2 A;  2JYQ A;  4U17 A;  1NZV A;  2OQ1 A;  1SPR A;  2RSY A;  2LQN A;  1TCE A;  4OHD A;  5EEQ A;  1XA6 A;  2K7A B;  2DM0 A;  1O4C A;  4K44 A;  5DC4 A;  1GHU A;  1GRI A;  3VS0 A;  4U1P A;  2H46 E;  1AOT F;  2FO0 A;  2L3T A;  5J3X A;  2Y1M A;  2ECD A;  2BBU A;  3KFJ A;  2H8H A;  3NHN A;  1CSY A;  5EHR A;  4K11 A;  5AUL A;  1O4J A;  1FBZ A;  1O4A A;  1A08 A;  2EO3 A;  1O4P A;  3PJP A;  3PLF B;  5HKZ A;  5EHP A;  2B3O A;  2AOB A;  3PQZ A;  1RJA A;  2ETZ A;  1D4T A;  3VRZ A;  4DGX A;  1QAD A;  2HDX A;  3OVE A;  2HUW A;  2CS0 A;  3VS6 A;  1SKJ A;  1LUI A;  3N84 A;  5EG3 B;  1YVH A;  3MAZ A;  1A07 A;  3M7F A;  1D1Z A;  5CDW A;  1O4O A;  1FMK A;  3VS5 A;  2L6K A;  1BF5 A;  3CD3 A;  3US4 A;  2PNA A;  4FBN A;  3PS5 A;  2YSX A;  3S8L A;  1R1Q A;  2EYY A;  2RVF A;  1KA6 A;  3BUN B;  2CIA A;  4NWG A;  2LNW A;  2OZO A;  1O47 A;  4FL2 A;  3OV1 A;  2C0I A;  2GSB A;  1O41 A;  1FHS A;  4GPL B;  2PLD A;  4XZ0 A;  1X6C A;  4E93 A;  1JYU A;  3T04 A;  1OPL A;  2PLE A;  2DLY A;  3QWY A;  1ZFP E;  2KK6 A;  1O4F A;  1SPS A;  5GJH A;  1O44 A;  3IMJ A;  1JWO A;  1JYR A;  1QCF A;  2CI8 A;  1A81 A;  1O49 A;  3LYV A;  2KNO A;  4WWQ A;  4H1O A;  1M61 A;  1LCJ A;  2MC1 A;  2VIF A;  1A1E A;  3BUO B;  4A4C A;  3S8O A;  4F5B A;  2EYV A;  2ABL A;  2XP1 A;  1RPY A;  2LCT A;  2EU0 A;  1CWE A;  1A1A A;  3VRP A;  1QG1 E;  1O4I A;  3TKZ A;  1HCT B;  1FU5 A;  2MRK A;  1O43 A;  4FL3 A;  4K45 A;  3CWG A;  2LRA A;  3VRQ A;  1BKM A;  1FBV A;  1CWD L;  1IS0 A;  2CRH A;  3VRN A;  3IMD A;  4K2R A;  1R1P A;  1LKL A;  1BHH A;  1K9A A;  1LUM A;  1D4W A;  4LUE A;  4M4Z A;  1M27 A;  3QWX X;  2KGY A;  3C7I A;  1UUR A;  2EKX A;  1X27 A;  1PIC A;  4P9Z A;  2DX0 A;  1P13 A;  3EAZ A;  4OHI A;  3EAC A;  4OHL A;  1AYD A;  3BUW B;  1AD5 A;  4OHH A;  1A09 A;  3BUM B;  1SHD A;  2C0O A;  3VS7 A;  3S9K A;  4XZ1 A;  2CI9 A;  1O4B A;  4P9V A;  3MXC A;  2HDV A;  1Y1U A;  5IBM A;  2LQW A;  2C9W A;  1JU5 A;  2ROR A;  3VGO A;  5DC0 B;  3GXX A;  1AOU F;  1O4R A;  1F1W A;  4A4B A;  3BUX B;  3VS3 A;  1BFI A;  4TZI A;  1A1C A;  5IBS A;  1AYA A;  1BKL A;  4DGP A;  3N8M A;  1IJR A;  3CBL A;  1B47 A;  3BKB A;  1R1S A;  1O4G A;  1O46 A;  1O4E A;  1WQU A;  2PTK A;  1G83 A;  2Y3A B;  1FU6 A;  1SHA A;  4X6S A;  3VS1 A;  1NRV A;  1O45 A;  3N7Y A;  1O4K A;  1AYC A;  1BFJ A;  3PSK A;  3VRR A;  1HCS B;  1UUS A;  2MRJ A;  3IN7 A;  1O4M A;  3HCK A;  1BMB A;  2DLZ A;  2EO6 A;  4QSY A;  1SHB A;  1MIL A;  1O4Q A;  3VS4 A;  2H5K A;  2CR4 A;  2C0T A;  2FCI A;  3OP0 A;  1X0N A;  5D0J A;  1OO3 A;  3VRY A;  1O42 A;  2HCK A;  1O4H A;  4LUD A;  4E68 A;  4OHE A;  4F5A A;  4JE4 A;  3K2M A;  3GQI B;  1TZE E;  4ROJ A;  5AXI A;  1CSZ A;  1JYQ A;  2Y1N A;  2IZV A;  1BHF A;  2K79 B;  3K2T A;  2GE9 A;  1OO4 A;  4JGH A;  5GJI A;  1AB2 A;  3HHM B;  3WA4 A;  1O48 A;  4JEG A;  1NZL A;  3VRO A;  1O4D A;  1MW4 A;  3PSJ A;  2L4K A;  1BG1 A; 
#chains in the Genus database with same CATH homology
 1I3Z A;  2SRC A;  2EYZ A;  2MQI A;  4GWF A;  2EOB A;  2IUH A;  5DC9 A;  2RMX A;  2IUI A;  5BO4 A;  1RQQ C;  3ZNI A;  5EEL A;  5HKW A;  4H34 A;  3CXL A;  3IN8 A;  5DF6 A;  2CBL A;  2QMS A;  2PNB A;  3UF4 A;  1H9O A;  2YU7 A;  1BLJ A;  3HIZ B;  3S8N A;  4EY0 A;  1BLK A;  2AOA A;  4L1B B;  3TL0 A;  1AYB A;  1Y57 A;  1O4L A;  5I6V A;  3OB1 B;  1KSW A;  2SHP A;  4NWF A;  4F59 A;  1BHH B;  2LNX A;  3VS2 A;  2MK2 A;  3GXW A;  1O4N A;  2IUG A;  2AUG A;  1CJ1 A;  3UYO A;  1BM2 A;  4GL9 E;  4EIH A;  1Z3K A;  4D8K A;  2EL8 A;  1F2F A;  3OB2 B;  5HKY A;  1LKK A;  2HMH A;  3MXY A;  1FYR A;  1LUK A;  1LCK A;  1OPK A;  3PFV A;  2DVJ A;  2DCR A;  1KA7 A;  1LUN A;  5KAZ A;  1A1B A;  1YVL A;  1KC2 A;  2JYQ A;  4U17 A;  1NZV A;  2OQ1 A;  1SPR A;  2RSY A;  2LQN A;  1TCE A;  4OHD A;  5EEQ A;  1XA6 A;  2K7A B;  2DM0 A;  1O4C A;  4K44 A;  5DC4 A;  1GHU A;  1GRI A;  3VS0 A;  4U1P A;  2H46 E;  1AOT F;  2FO0 A;  2L3T A;  5J3X A;  2Y1M A;  2ECD A;  2BBU A;  3KFJ A;  2H8H A;  3NHN A;  1CSY A;  5EHR A;  4K11 A;  5AUL A;  1O4J A;  1FBZ A;  1O4A A;  1A08 A;  2EO3 A;  1O4P A;  3PJP A;  3PLF B;  5HKZ A;  5EHP A;  2B3O A;  2AOB A;  3PQZ A;  1RJA A;  2ETZ A;  1D4T A;  3VRZ A;  4DGX A;  1QAD A;  2HDX A;  3OVE A;  2HUW A;  2CS0 A;  3VS6 A;  1SKJ A;  1LUI A;  3N84 A;  5EG3 B;  1YVH A;  3MAZ A;  1A07 A;  3M7F A;  1D1Z A;  5CDW A;  1O4O A;  1FMK A;  3VS5 A;  2L6K A;  1BF5 A;  3CD3 A;  3US4 A;  2PNA A;  4FBN A;  3PS5 A;  2YSX A;  3S8L A;  1R1Q A;  2EYY A;  2RVF A;  1KA6 A;  3BUN B;  2CIA A;  4NWG A;  2LNW A;  2OZO A;  1O47 A;  4FL2 A;  3OV1 A;  2C0I A;  2GSB A;  1O41 A;  1FHS A;  4GPL B;  2PLD A;  4XZ0 A;  1X6C A;  4E93 A;  1JYU A;  3T04 A;  1OPL A;  2PLE A;  2DLY A;  3QWY A;  1ZFP E;  2KK6 A;  1O4F A;  1SPS A;  5GJH A;  1O44 A;  3IMJ A;  1JWO A;  1JYR A;  1QCF A;  2CI8 A;  1A81 A;  1O49 A;  2KNO A;  4WWQ A;  4H1O A;  1M61 A;  1LCJ A;  2MC1 A;  2VIF A;  1A1E A;  3BUO B;  4A4C A;  3S8O A;  4F5B A;  2EYV A;  2ABL A;  2XP1 A;  1RPY A;  2LCT A;  2EU0 A;  1CWE A;  1A1A A;  3VRP A;  1QG1 E;  1O4I A;  3TKZ A;  1HCT B;  1FU5 A;  2MRK A;  1O43 A;  4FL3 A;  4K45 A;  3CWG A;  3VRQ A;  1BKM A;  1FBV A;  1CWD L;  1IS0 A;  2CRH A;  3VRN A;  3IMD A;  4K2R A;  1R1P A;  1LKL A;  1BHH A;  1K9A A;  1LUM A;  1D4W A;  4LUE A;  4M4Z A;  1M27 A;  3QWX X;  3C7I A;  1UUR A;  2EKX A;  1X27 A;  1PIC A;  4P9Z A;  2DX0 A;  1P13 A;  3EAZ A;  4OHI A;  3EAC A;  4OHL A;  1AYD A;  3BUW B;  1AD5 A;  4OHH A;  1A09 A;  3BUM B;  1SHD A;  2C0O A;  3VS7 A;  3S9K A;  4XZ1 A;  2CI9 A;  1O4B A;  4P9V A;  3MXC A;  2HDV A;  1Y1U A;  5IBM A;  2LQW A;  2C9W A;  1JU5 A;  2ROR A;  3VGO A;  5DC0 B;  3GXX A;  1AOU F;  1O4R A;  1F1W A;  4A4B A;  3BUX B;  3VS3 A;  1BFI A;  4TZI A;  1A1C A;  5IBS A;  1AYA A;  1BKL A;  4DGP A;  3N8M A;  1IJR A;  3CBL A;  1B47 A;  3BKB A;  1R1S A;  1O4G A;  1O46 A;  1O4E A;  1WQU A;  2PTK A;  1G83 A;  2Y3A B;  1FU6 A;  1SHA A;  4X6S A;  3VS1 A;  1NRV A;  1O45 A;  3N7Y A;  1O4K A;  1AYC A;  1BFJ A;  3PSK A;  3VRR A;  1HCS B;  1UUS A;  2MRJ A;  3IN7 A;  1O4M A;  3HCK A;  1BMB A;  2DLZ A;  2EO6 A;  4QSY A;  1SHB A;  1MIL A;  1O4Q A;  3VS4 A;  2H5K A;  2CR4 A;  2C0T A;  2FCI A;  3OP0 A;  1X0N A;  5D0J A;  1OO3 A;  3VRY A;  1O42 A;  2HCK A;  1O4H A;  4LUD A;  4E68 A;  4OHE A;  4F5A A;  4JE4 A;  3K2M A;  3GQI B;  1TZE E;  4ROJ A;  5AXI A;  1CSZ A;  1JYQ A;  2Y1N A;  2IZV A;  1BHF A;  2K79 B;  2GE9 A;  1OO4 A;  4JGH A;  5GJI A;  1AB2 A;  3HHM B;  3WA4 A;  1O48 A;  4JEG A;  1NZL A;  3VRO A;  1O4D A;  1MW4 A;  3PSJ A;  2L4K A;  1BG1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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