1X6CA

Solution structures of the sh2 domain of human protein-tyrosine phosphatase shp-1
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
118
structure length
118
Chain Sequence
GSSGSSGWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYSGPSSG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 6
total genus 13
structure length 118
sequence length 118
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1x6cA00
3MXYA 3T04A 2H46E 1O4FA 4EY0A 2B3OA 1F2FA 1CJ1A 1AOUF 4FL3A 5KAZA 1X27A 2XP1A 4ROJA 3VS5A 2KK6A 3IMDA 2CI8A 1K9AA 2EO3A 3PQZA 4EIHA 1BFIA 2BBUA 1BKMA 1LUMA 2C9WA 2YSXA 1FU5A 1KC2A 5J3XA 1OPLA 3HIZB 1QG1E 1M61A 3PLFB 3C7IA 2AOBA 3OB1B 1FU6A 2EL8A 3IN7A 1X0NA 1M27A 2L3TA 3PSKA 2CBLA 4XZ1A 3BUNB 2DM0A 2EYZA 2GSBA 2MK2A 1A1EA 1O4JA 3TKZA 1IJRA 4K2RA 2CI9A 2IUHA 2PNAA 1O47A 4OHIA 1LUNA 1R1PA 1AYDA 5AULA 2HCKA 1SHBA 3EACA 1AYAA 4LUEA 3US4A 2DVJA 1KA7A 4GWFA 3VRQA 1OO4A 1RQQC 2AUGA 3VRRA 1FMKA 1Y57A 4E68A 4FBNA 4QSYA 4U17A 2CRHA 5IBMA 3S8OA 5IBSA 1A09A 2DCRA 2LQWA 1BKLA 1BM2A 1OO3A 4X6SA 1O4EA 4K45A 3GXXA 1H9OA 3BUOB 1RJAA 1BG1A 1O4BA 1AD5A 4JE4A 2CIAA 2SRCA 1AB2A 2HDVA 5DF6A 2KNOA 2LQNA 1OPKA 5EELA 1JYQA 2RVFA 3S8NA 5EEQA 3CBLA 1BHHB 1O4AA 4NWGA 2EOBA 1YVLA 1O4DA 2MC1A 4L1BB 1FBVA 4A4CA 1SHDA 2H5KA 3UF4A 1A07A 3VRPA 2LNXA 3N8MA 1WQUA 1O4HA 4NWFA 1GRIA 1SPRA 3QWYA 2HUWA 2PLEA 5DC0B 2IUIA 3VS6A 2ETZA 3K2MA 3HHMB 5GJIA 1UUSA 2K79B 4LUDA 2CS0A 4GL9E 1B47A 1RPYA 1BMBA 1LUIA 1BHFA 3IMJA 5I6VA 1BLJA 1O4NA 1D4TA 3ZNIA 1ZFPE 2JYQA 5BO4A 1P13A 2FO0A 4K44A 2DX0A 1A1BA 3VS0A 5AXIA 2PTKA 1LCJA 1X6CA 1D4WA 3S8LA 3S9KA 3N84A 3VS2A 2MRKA 4D8KA 2MRJA 2IZVA 1I3ZA 1O4QA 1YVHA 3CWGA 3PFVA 4A4BA 4F5BA 4OHEA 1BF5A 3GXWA 1CWDL 3GQIB 1BLKA 1MW4A 4TZIA 5EHPA 3OB2B 4K11A 4FL2A 3OV1A 2AOAA 3VS4A 2RMXA 1PICA 1O41A 1TZEE 1XA6A 3VS3A 1TCEA 1JYUA 2PNBA 1O45A 1O43A 1JWOA 2DLZA 2YU7A 4OHLA 4OHDA 3BUWB 1A81A 3VGOA 2HDXA 5GJHA 1O4RA 2EU0A 1O4IA 1O4OA 5HKYA 1O4PA 2FCIA 1LKKA 3M7FA 1HCSB 3OP0A 1NRVA 4F5AA 4E93A 1FBZA 1CSYA 1HCTB 1SHAA 1O44A 3NHNA 2EYVA 4P9VA 4XZ0A 3BUXB 1O4MA 1A1AA 2SHPA 4GPLB 1JU5A 3VROA 1FYRA 4WWQA 2OQ1A 1A1CA 1O4GA 1KSWA 4F59A 3HCKA 5HKZA 3OVEA 4M4ZA 2DLYA 1O4LA 3PS5A 1Z3KA 1O49A 2C0IA 4DGPA 1MILA 2C0OA 3CD3A 3TL0A 2CR4A 2C0TA 3VS7A 2EKXA 5EG3B 1JYRA 1NZLA 1SKJA 1LCKA 3N7YA 4JGHA 2L4KA 1GHUA 2EO6A 2GE9A 1AYCA 4DGXA 1LUKA 3MXCA 4U1PA 1D1ZA 1A08A 3VS1A 2K7AB 2VIFA 3PJPA 1CWEA 1FHSA 1O4KA 1UURA 2OZOA 1O4CA 4P9ZA 5D0JA 3VRYA 2ABLA 1QADA 3UYOA 5EHRA 1SPSA 5CDWA 2LNWA 4JEGA 1QCFA 2RSYA 2IUGA 4OHHA 1CSZA 2RORA 2Y1MA 2Y3AB 3PSJA 1R1SA 3EAZA 1BHHA 2HMHA 3KFJA 1O42A 5HKWA 2L6KA 2Y1NA 1G83A 1IS0A 1F1WA 2ECDA 5DC4A 1LKLA 3VRZA 3IN8A 5DC9A 3BUMB 3CXLA 3WA4A 3VRNA 1Y1UA 1O48A 2QMSA 3BKBA 2MQIA 1AOTF 1R1QA 2PLDA 3QWXX 2EYYA 1KA6A 1O46A 3MAZA 1NZVA 1BFJA 2LCTA 2H8HA 4H1OA 1AYBA 4H34A
chains in the Genus database with same CATH superfamily
3MXYA 3T04A 2H46E 1O4FA 4EY0A 2B3OA 1F2FA 1CJ1A 1AOUF 4FL3A 5KAZA 1X27A 2XP1A 4ROJA 3VS5A 2KK6A 3IMDA 2CI8A 1K9AA 2EO3A 3PQZA 4EIHA 1BFIA 2BBUA 1BKMA 1LUMA 2C9WA 2YSXA 1FU5A 1KC2A 5J3XA 1OPLA 3HIZB 1QG1E 1M61A 3PLFB 3C7IA 2AOBA 3OB1B 1FU6A 2EL8A 3IN7A 1X0NA 1M27A 2L3TA 3PSKA 2CBLA 4XZ1A 3BUNB 2DM0A 2EYZA 2GSBA 2MK2A 1A1EA 1O4JA 3TKZA 1IJRA 4K2RA 2CI9A 2IUHA 2PNAA 1O47A 4OHIA 1LUNA 1R1PA 1AYDA 5AULA 2HCKA 1SHBA 3EACA 1AYAA 4LUEA 3US4A 2DVJA 1KA7A 4GWFA 3VRQA 1OO4A 1RQQC 2AUGA 3VRRA 1FMKA 1Y57A 4E68A 4FBNA 3K2TA 4QSYA 4U17A 2CRHA 5IBMA 3S8OA 5IBSA 2KGYA 1A09A 2DCRA 2LQWA 1BKLA 1BM2A 1OO3A 4X6SA 1O4EA 4K45A 3GXXA 1H9OA 3BUOB 1RJAA 1BG1A 1O4BA 1AD5A 4JE4A 2CIAA 2SRCA 1AB2A 2HDVA 5DF6A 2KNOA 2LQNA 1OPKA 5EELA 1JYQA 2RVFA 3LYVA 3S8NA 5EEQA 3CBLA 1BHHB 1O4AA 4NWGA 2EOBA 1YVLA 1O4DA 2MC1A 4L1BB 1FBVA 4A4CA 1SHDA 2H5KA 3UF4A 1A07A 3VRPA 2LNXA 3N8MA 1WQUA 1O4HA 4NWFA 1GRIA 1SPRA 3QWYA 2HUWA 2PLEA 5DC0B 2IUIA 3VS6A 2ETZA 3K2MA 3HHMB 5GJIA 1UUSA 2K79B 4LUDA 2CS0A 4GL9E 1B47A 1RPYA 1BMBA 1LUIA 1BHFA 3IMJA 5I6VA 1BLJA 1O4NA 1D4TA 3ZNIA 1ZFPE 2JYQA 5BO4A 1P13A 2FO0A 4K44A 2DX0A 1A1BA 3VS0A 5AXIA 2PTKA 1LCJA 1X6CA 1D4WA 3S8LA 3S9KA 3N84A 3VS2A 2MRKA 4D8KA 2MRJA 2IZVA 1I3ZA 1O4QA 1YVHA 3CWGA 3PFVA 4A4BA 4F5BA 4OHEA 1BF5A 3GXWA 1CWDL 3GQIB 1BLKA 1MW4A 4TZIA 5EHPA 3OB2B 4K11A 4FL2A 3OV1A 2AOAA 3VS4A 2RMXA 1PICA 1O41A 1TZEE 1XA6A 3VS3A 1TCEA 1JYUA 2PNBA 1O45A 1O43A 1JWOA 2DLZA 2YU7A 4OHLA 4OHDA 3BUWB 1A81A 3VGOA 2HDXA 5GJHA 1O4RA 2EU0A 1O4IA 1O4OA 5HKYA 1O4PA 2FCIA 1LKKA 3M7FA 1HCSB 3OP0A 1NRVA 4F5AA 4E93A 1FBZA 1CSYA 1HCTB 1SHAA 1O44A 3NHNA 2EYVA 4P9VA 4XZ0A 3BUXB 1O4MA 1A1AA 2SHPA 4GPLB 1JU5A 3VROA 1FYRA 4WWQA 2OQ1A 1A1CA 1O4GA 1KSWA 4F59A 3HCKA 5HKZA 3OVEA 4M4ZA 2DLYA 1O4LA 3PS5A 1Z3KA 1O49A 2C0IA 4DGPA 1MILA 2C0OA 3CD3A 3TL0A 2CR4A 2C0TA 3VS7A 2EKXA 5EG3B 1JYRA 1NZLA 1SKJA 1LCKA 3N7YA 4JGHA 2L4KA 1GHUA 2EO6A 2GE9A 1AYCA 4DGXA 1LUKA 3MXCA 4U1PA 1D1ZA 1A08A 3VS1A 2K7AB 2VIFA 3PJPA 1CWEA 1FHSA 1O4KA 1UURA 2OZOA 1O4CA 4P9ZA 5D0JA 3VRYA 2ABLA 1QADA 3UYOA 5EHRA 1SPSA 5CDWA 2LNWA 4JEGA 1QCFA 2RSYA 2IUGA 4OHHA 1CSZA 2RORA 2Y1MA 2Y3AB 3PSJA 1R1SA 3EAZA 1BHHA 2HMHA 3KFJA 1O42A 5HKWA 2L6KA 2Y1NA 1G83A 1IS0A 1F1WA 2ECDA 5DC4A 1LKLA 3VRZA 3IN8A 5DC9A 3BUMB 3CXLA 3WA4A 3VRNA 1Y1UA 1O48A 2QMSA 3BKBA 2MQIA 1AOTF 1R1QA 2PLDA 3QWXX 2EYYA 1KA6A 1O46A 3MAZA 1NZVA 2LRAA 1BFJA 2LCTA 2H8HA 4H1OA 1AYBA 4H34A
chains in the Genus database with same CATH topology
3MXYA 3T04A 2H46E 1O4FA 4EY0A 2B3OA 1F2FA 1CJ1A 1AOUF 4FL3A 5KAZA 1X27A 2XP1A 4ROJA 3VS5A 2KK6A 3IMDA 2CI8A 1K9AA 2EO3A 3PQZA 4EIHA 1BFIA 2BBUA 1BKMA 1LUMA 2C9WA 2YSXA 1FU5A 1KC2A 5J3XA 1OPLA 3HIZB 1QG1E 1M61A 3PLFB 3C7IA 2AOBA 3OB1B 1FU6A 2EL8A 3IN7A 1X0NA 1M27A 2L3TA 3PSKA 2CBLA 4XZ1A 3BUNB 2DM0A 2EYZA 2GSBA 2MK2A 1A1EA 1O4JA 3TKZA 1IJRA 4K2RA 2CI9A 2IUHA 2PNAA 1O47A 4OHIA 1LUNA 1R1PA 1AYDA 5AULA 2HCKA 1SHBA 3EACA 1AYAA 4LUEA 3US4A 2DVJA 1KA7A 4GWFA 3VRQA 1OO4A 1RQQC 2AUGA 3VRRA 1FMKA 1Y57A 4E68A 4FBNA 4QSYA 4U17A 2CRHA 5IBMA 3S8OA 5IBSA 1A09A 2DCRA 2LQWA 1BKLA 1BM2A 1OO3A 4X6SA 1O4EA 4K45A 3GXXA 1H9OA 3BUOB 1RJAA 1BG1A 1O4BA 1AD5A 4JE4A 2CIAA 2SRCA 1AB2A 2HDVA 5DF6A 2KNOA 2LQNA 1OPKA 5EELA 1JYQA 2RVFA 3S8NA 5EEQA 3CBLA 1BHHB 1O4AA 4NWGA 2EOBA 1YVLA 1O4DA 2MC1A 4L1BB 1FBVA 4A4CA 1SHDA 2H5KA 3UF4A 1A07A 3VRPA 2LNXA 3N8MA 1WQUA 1O4HA 4NWFA 1GRIA 1SPRA 3QWYA 2HUWA 2PLEA 5DC0B 2IUIA 3VS6A 2ETZA 3K2MA 3HHMB 5GJIA 1UUSA 2K79B 4LUDA 2CS0A 4GL9E 1B47A 1RPYA 1BMBA 1LUIA 1BHFA 3IMJA 5I6VA 1BLJA 1O4NA 1D4TA 3ZNIA 1ZFPE 2JYQA 5BO4A 1P13A 2FO0A 4K44A 2DX0A 1A1BA 3VS0A 5AXIA 2PTKA 1LCJA 1X6CA 1D4WA 3S8LA 3S9KA 3N84A 3VS2A 2MRKA 4D8KA 2MRJA 2IZVA 1I3ZA 1O4QA 1YVHA 3CWGA 3PFVA 4A4BA 4F5BA 4OHEA 1BF5A 3GXWA 1CWDL 3GQIB 1BLKA 1MW4A 4TZIA 5EHPA 3OB2B 4K11A 4FL2A 3OV1A 2AOAA 3VS4A 2RMXA 1PICA 1O41A 1TZEE 1XA6A 3VS3A 1TCEA 1JYUA 2PNBA 1O45A 1O43A 1JWOA 2DLZA 2YU7A 4OHLA 4OHDA 3BUWB 1A81A 3VGOA 2HDXA 5GJHA 1O4RA 2EU0A 1O4IA 1O4OA 5HKYA 1O4PA 2FCIA 1LKKA 3M7FA 1HCSB 3OP0A 1NRVA 4F5AA 4E93A 1FBZA 1CSYA 1HCTB 1SHAA 1O44A 3NHNA 2EYVA 4P9VA 4XZ0A 3BUXB 1O4MA 1A1AA 2SHPA 4GPLB 1JU5A 3VROA 1FYRA 4WWQA 2OQ1A 1A1CA 1O4GA 1KSWA 4F59A 3HCKA 5HKZA 3OVEA 4M4ZA 2DLYA 1O4LA 3PS5A 1Z3KA 1O49A 2C0IA 4DGPA 1MILA 2C0OA 3CD3A 3TL0A 2CR4A 2C0TA 3VS7A 2EKXA 5EG3B 1JYRA 1NZLA 1SKJA 1LCKA 3N7YA 4JGHA 2L4KA 1GHUA 2EO6A 2GE9A 1AYCA 4DGXA 1LUKA 3MXCA 4U1PA 1D1ZA 1A08A 3VS1A 2K7AB 2VIFA 3PJPA 1CWEA 1FHSA 1O4KA 1UURA 2OZOA 1O4CA 4P9ZA 5D0JA 3VRYA 2ABLA 1QADA 3UYOA 5EHRA 1SPSA 5CDWA 2LNWA 4JEGA 1QCFA 2RSYA 2IUGA 4OHHA 1CSZA 2RORA 2Y1MA 2Y3AB 3PSJA 1R1SA 3EAZA 1BHHA 2HMHA 3KFJA 1O42A 5HKWA 2L6KA 2Y1NA 1G83A 1IS0A 1F1WA 2ECDA 5DC4A 1LKLA 3VRZA 3IN8A 5DC9A 3BUMB 3CXLA 3WA4A 3VRNA 1Y1UA 1O48A 2QMSA 3BKBA 2MQIA 1AOTF 1R1QA 2PLDA 3QWXX 2EYYA 1KA6A 1O46A 3MAZA 1NZVA 1BFJA 2LCTA 2H8HA 4H1OA 1AYBA 4H34A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MXY A;  3T04 A;  2H46 E;  1O4F A;  4EY0 A;  2B3O A;  1F2F A;  1CJ1 A;  1AOU F;  4FL3 A;  5KAZ A;  1X27 A;  2XP1 A;  4ROJ A;  3VS5 A;  2KK6 A;  3IMD A;  2CI8 A;  1K9A A;  2EO3 A;  3PQZ A;  4EIH A;  1BFI A;  2BBU A;  1BKM A;  1LUM A;  2C9W A;  2YSX A;  1FU5 A;  1KC2 A;  5J3X A;  1OPL A;  3HIZ B;  1QG1 E;  1M61 A;  3PLF B;  3C7I A;  2AOB A;  3OB1 B;  1FU6 A;  2EL8 A;  3IN7 A;  1X0N A;  1M27 A;  2L3T A;  3PSK A;  2CBL A;  4XZ1 A;  3BUN B;  2DM0 A;  2EYZ A;  2GSB A;  2MK2 A;  1A1E A;  1O4J A;  3TKZ A;  1IJR A;  4K2R A;  2CI9 A;  2IUH A;  2PNA A;  1O47 A;  4OHI A;  1LUN A;  1R1P A;  1AYD A;  5AUL A;  2HCK A;  1SHB A;  3EAC A;  1AYA A;  4LUE A;  3US4 A;  2DVJ A;  1KA7 A;  4GWF A;  3VRQ A;  1OO4 A;  1RQQ C;  2AUG A;  3VRR A;  1FMK A;  1Y57 A;  4E68 A;  4FBN A;  4QSY A;  4U17 A;  2CRH A;  5IBM A;  3S8O A;  5IBS A;  1A09 A;  2DCR A;  2LQW A;  1BKL A;  1BM2 A;  1OO3 A;  4X6S A;  1O4E A;  4K45 A;  3GXX A;  1H9O A;  3BUO B;  1RJA A;  1BG1 A;  1O4B A;  1AD5 A;  4JE4 A;  2CIA A;  2SRC A;  1AB2 A;  2HDV A;  5DF6 A;  2KNO A;  2LQN A;  1OPK A;  5EEL A;  1JYQ A;  2RVF A;  3S8N A;  5EEQ A;  3CBL A;  1BHH B;  1O4A A;  4NWG A;  2EOB A;  1YVL A;  1O4D A;  2MC1 A;  4L1B B;  1FBV A;  4A4C A;  1SHD A;  2H5K A;  3UF4 A;  1A07 A;  3VRP A;  2LNX A;  3N8M A;  1WQU A;  1O4H A;  4NWF A;  1GRI A;  1SPR A;  3QWY A;  2HUW A;  2PLE A;  5DC0 B;  2IUI A;  3VS6 A;  2ETZ A;  3K2M A;  3HHM B;  5GJI A;  1UUS A;  2K79 B;  4LUD A;  2CS0 A;  4GL9 E;  1B47 A;  1RPY A;  1BMB A;  1LUI A;  1BHF A;  3IMJ A;  5I6V A;  1BLJ A;  1O4N A;  1D4T A;  3ZNI A;  1ZFP E;  2JYQ A;  5BO4 A;  1P13 A;  2FO0 A;  4K44 A;  2DX0 A;  1A1B A;  3VS0 A;  5AXI A;  2PTK A;  1LCJ A;  1X6C A;  1D4W A;  3S8L A;  3S9K A;  3N84 A;  3VS2 A;  2MRK A;  4D8K A;  2MRJ A;  2IZV A;  1I3Z A;  1O4Q A;  1YVH A;  3CWG A;  3PFV A;  4A4B A;  4F5B A;  4OHE A;  1BF5 A;  3GXW A;  1CWD L;  3GQI B;  1BLK A;  1MW4 A;  4TZI A;  5EHP A;  3OB2 B;  4K11 A;  4FL2 A;  3OV1 A;  2AOA A;  3VS4 A;  2RMX A;  1PIC A;  1O41 A;  1TZE E;  1XA6 A;  3VS3 A;  1TCE A;  1JYU A;  2PNB A;  1O45 A;  1O43 A;  1JWO A;  2DLZ A;  2YU7 A;  4OHL A;  4OHD A;  3BUW B;  1A81 A;  3VGO A;  2HDX A;  5GJH A;  1O4R A;  2EU0 A;  1O4I A;  1O4O A;  5HKY A;  1O4P A;  2FCI A;  1LKK A;  3M7F A;  1HCS B;  3OP0 A;  1NRV A;  4F5A A;  4E93 A;  1FBZ A;  1CSY A;  1HCT B;  1SHA A;  1O44 A;  3NHN A;  2EYV A;  4P9V A;  4XZ0 A;  3BUX B;  1O4M A;  1A1A A;  2SHP A;  4GPL B;  1JU5 A;  3VRO A;  1FYR A;  4WWQ A;  2OQ1 A;  1A1C A;  1O4G A;  1KSW A;  4F59 A;  3HCK A;  5HKZ A;  3OVE A;  4M4Z A;  2DLY A;  1O4L A;  3PS5 A;  1Z3K A;  1O49 A;  2C0I A;  4DGP A;  1MIL A;  2C0O A;  3CD3 A;  3TL0 A;  2CR4 A;  2C0T A;  3VS7 A;  2EKX A;  5EG3 B;  1JYR A;  1NZL A;  1SKJ A;  1LCK A;  3N7Y A;  4JGH A;  2L4K A;  1GHU A;  2EO6 A;  2GE9 A;  1AYC A;  4DGX A;  1LUK A;  3MXC A;  4U1P A;  1D1Z A;  1A08 A;  3VS1 A;  2K7A B;  2VIF A;  3PJP A;  1CWE A;  1FHS A;  1O4K A;  1UUR A;  2OZO A;  1O4C A;  4P9Z A;  5D0J A;  3VRY A;  2ABL A;  1QAD A;  3UYO A;  5EHR A;  1SPS A;  5CDW A;  2LNW A;  4JEG A;  1QCF A;  2RSY A;  2IUG A;  4OHH A;  1CSZ A;  2ROR A;  2Y1M A;  2Y3A B;  3PSJ A;  1R1S A;  3EAZ A;  1BHH A;  2HMH A;  3KFJ A;  1O42 A;  5HKW A;  2L6K A;  2Y1N A;  1G83 A;  1IS0 A;  1F1W A;  2ECD A;  5DC4 A;  1LKL A;  3VRZ A;  3IN8 A;  5DC9 A;  3BUM B;  3CXL A;  3WA4 A;  3VRN A;  1Y1U A;  1O48 A;  2QMS A;  3BKB A;  2MQI A;  1AOT F;  1R1Q A;  2PLD A;  3QWX X;  2EYY A;  1KA6 A;  1O46 A;  3MAZ A;  1NZV A;  1BFJ A;  2LCT A;  2H8H A;  4H1O A;  1AYB A;  4H34 A; 
#chains in the Genus database with same CATH topology
 3MXY A;  3T04 A;  2H46 E;  1O4F A;  4EY0 A;  2B3O A;  1F2F A;  1CJ1 A;  1AOU F;  4FL3 A;  5KAZ A;  1X27 A;  2XP1 A;  4ROJ A;  3VS5 A;  2KK6 A;  3IMD A;  2CI8 A;  1K9A A;  2EO3 A;  3PQZ A;  4EIH A;  1BFI A;  2BBU A;  1BKM A;  1LUM A;  2C9W A;  2YSX A;  1FU5 A;  1KC2 A;  5J3X A;  1OPL A;  3HIZ B;  1QG1 E;  1M61 A;  3PLF B;  3C7I A;  2AOB A;  3OB1 B;  1FU6 A;  2EL8 A;  3IN7 A;  1X0N A;  1M27 A;  2L3T A;  3PSK A;  2CBL A;  4XZ1 A;  3BUN B;  2DM0 A;  2EYZ A;  2GSB A;  2MK2 A;  1A1E A;  1O4J A;  3TKZ A;  1IJR A;  4K2R A;  2CI9 A;  2IUH A;  2PNA A;  1O47 A;  4OHI A;  1LUN A;  1R1P A;  1AYD A;  5AUL A;  2HCK A;  1SHB A;  3EAC A;  1AYA A;  4LUE A;  3US4 A;  2DVJ A;  1KA7 A;  4GWF A;  3VRQ A;  1OO4 A;  1RQQ C;  2AUG A;  3VRR A;  1FMK A;  1Y57 A;  4E68 A;  4FBN A;  3K2T A;  4QSY A;  4U17 A;  2CRH A;  5IBM A;  3S8O A;  5IBS A;  2KGY A;  1A09 A;  2DCR A;  2LQW A;  1BKL A;  1BM2 A;  1OO3 A;  4X6S A;  1O4E A;  4K45 A;  3GXX A;  1H9O A;  3BUO B;  1RJA A;  1BG1 A;  1O4B A;  1AD5 A;  4JE4 A;  2CIA A;  2SRC A;  1AB2 A;  2HDV A;  5DF6 A;  2KNO A;  2LQN A;  1OPK A;  5EEL A;  1JYQ A;  2RVF A;  3LYV A;  3S8N A;  5EEQ A;  3CBL A;  1BHH B;  1O4A A;  4NWG A;  2EOB A;  1YVL A;  1O4D A;  2MC1 A;  4L1B B;  1FBV A;  4A4C A;  1SHD A;  2H5K A;  3UF4 A;  1A07 A;  3VRP A;  2LNX A;  3N8M A;  1WQU A;  1O4H A;  4NWF A;  1GRI A;  1SPR A;  3QWY A;  2HUW A;  2PLE A;  5DC0 B;  2IUI A;  3VS6 A;  2ETZ A;  3K2M A;  3HHM B;  5GJI A;  1UUS A;  2K79 B;  4LUD A;  2CS0 A;  4GL9 E;  1B47 A;  1RPY A;  1BMB A;  1LUI A;  1BHF A;  3IMJ A;  5I6V A;  1BLJ A;  1O4N A;  1D4T A;  3ZNI A;  1ZFP E;  2JYQ A;  5BO4 A;  1P13 A;  2FO0 A;  4K44 A;  2DX0 A;  1A1B A;  3VS0 A;  5AXI A;  2PTK A;  1LCJ A;  1X6C A;  1D4W A;  3S8L A;  3S9K A;  3N84 A;  3VS2 A;  2MRK A;  4D8K A;  2MRJ A;  2IZV A;  1I3Z A;  1O4Q A;  1YVH A;  3CWG A;  3PFV A;  4A4B A;  4F5B A;  4OHE A;  1BF5 A;  3GXW A;  1CWD L;  3GQI B;  1BLK A;  1MW4 A;  4TZI A;  5EHP A;  3OB2 B;  4K11 A;  4FL2 A;  3OV1 A;  2AOA A;  3VS4 A;  2RMX A;  1PIC A;  1O41 A;  1TZE E;  1XA6 A;  3VS3 A;  1TCE A;  1JYU A;  2PNB A;  1O45 A;  1O43 A;  1JWO A;  2DLZ A;  2YU7 A;  4OHL A;  4OHD A;  3BUW B;  1A81 A;  3VGO A;  2HDX A;  5GJH A;  1O4R A;  2EU0 A;  1O4I A;  1O4O A;  5HKY A;  1O4P A;  2FCI A;  1LKK A;  3M7F A;  1HCS B;  3OP0 A;  1NRV A;  4F5A A;  4E93 A;  1FBZ A;  1CSY A;  1HCT B;  1SHA A;  1O44 A;  3NHN A;  2EYV A;  4P9V A;  4XZ0 A;  3BUX B;  1O4M A;  1A1A A;  2SHP A;  4GPL B;  1JU5 A;  3VRO A;  1FYR A;  4WWQ A;  2OQ1 A;  1A1C A;  1O4G A;  1KSW A;  4F59 A;  3HCK A;  5HKZ A;  3OVE A;  4M4Z A;  2DLY A;  1O4L A;  3PS5 A;  1Z3K A;  1O49 A;  2C0I A;  4DGP A;  1MIL A;  2C0O A;  3CD3 A;  3TL0 A;  2CR4 A;  2C0T A;  3VS7 A;  2EKX A;  5EG3 B;  1JYR A;  1NZL A;  1SKJ A;  1LCK A;  3N7Y A;  4JGH A;  2L4K A;  1GHU A;  2EO6 A;  2GE9 A;  1AYC A;  4DGX A;  1LUK A;  3MXC A;  4U1P A;  1D1Z A;  1A08 A;  3VS1 A;  2K7A B;  2VIF A;  3PJP A;  1CWE A;  1FHS A;  1O4K A;  1UUR A;  2OZO A;  1O4C A;  4P9Z A;  5D0J A;  3VRY A;  2ABL A;  1QAD A;  3UYO A;  5EHR A;  1SPS A;  5CDW A;  2LNW A;  4JEG A;  1QCF A;  2RSY A;  2IUG A;  4OHH A;  1CSZ A;  2ROR A;  2Y1M A;  2Y3A B;  3PSJ A;  1R1S A;  3EAZ A;  1BHH A;  2HMH A;  3KFJ A;  1O42 A;  5HKW A;  2L6K A;  2Y1N A;  1G83 A;  1IS0 A;  1F1W A;  2ECD A;  5DC4 A;  1LKL A;  3VRZ A;  3IN8 A;  5DC9 A;  3BUM B;  3CXL A;  3WA4 A;  3VRN A;  1Y1U A;  1O48 A;  2QMS A;  3BKB A;  2MQI A;  1AOT F;  1R1Q A;  2PLD A;  3QWX X;  2EYY A;  1KA6 A;  1O46 A;  3MAZ A;  1NZV A;  2LRA A;  1BFJ A;  2LCT A;  2H8H A;  4H1O A;  1AYB A;  4H34 A; 
#chains in the Genus database with same CATH homology
 3MXY A;  3T04 A;  2H46 E;  1O4F A;  4EY0 A;  2B3O A;  1F2F A;  1CJ1 A;  1AOU F;  4FL3 A;  5KAZ A;  1X27 A;  2XP1 A;  4ROJ A;  3VS5 A;  2KK6 A;  3IMD A;  2CI8 A;  1K9A A;  2EO3 A;  3PQZ A;  4EIH A;  1BFI A;  2BBU A;  1BKM A;  1LUM A;  2C9W A;  2YSX A;  1FU5 A;  1KC2 A;  5J3X A;  1OPL A;  3HIZ B;  1QG1 E;  1M61 A;  3PLF B;  3C7I A;  2AOB A;  3OB1 B;  1FU6 A;  2EL8 A;  3IN7 A;  1X0N A;  1M27 A;  2L3T A;  3PSK A;  2CBL A;  4XZ1 A;  3BUN B;  2DM0 A;  2EYZ A;  2GSB A;  2MK2 A;  1A1E A;  1O4J A;  3TKZ A;  1IJR A;  4K2R A;  2CI9 A;  2IUH A;  2PNA A;  1O47 A;  4OHI A;  1LUN A;  1R1P A;  1AYD A;  5AUL A;  2HCK A;  1SHB A;  3EAC A;  1AYA A;  4LUE A;  3US4 A;  2DVJ A;  1KA7 A;  4GWF A;  3VRQ A;  1OO4 A;  1RQQ C;  2AUG A;  3VRR A;  1FMK A;  1Y57 A;  4E68 A;  4FBN A;  4QSY A;  4U17 A;  2CRH A;  5IBM A;  3S8O A;  5IBS A;  1A09 A;  2DCR A;  2LQW A;  1BKL A;  1BM2 A;  1OO3 A;  4X6S A;  1O4E A;  4K45 A;  3GXX A;  1H9O A;  3BUO B;  1RJA A;  1BG1 A;  1O4B A;  1AD5 A;  4JE4 A;  2CIA A;  2SRC A;  1AB2 A;  2HDV A;  5DF6 A;  2KNO A;  2LQN A;  1OPK A;  5EEL A;  1JYQ A;  2RVF A;  3S8N A;  5EEQ A;  3CBL A;  1BHH B;  1O4A A;  4NWG A;  2EOB A;  1YVL A;  1O4D A;  2MC1 A;  4L1B B;  1FBV A;  4A4C A;  1SHD A;  2H5K A;  3UF4 A;  1A07 A;  3VRP A;  2LNX A;  3N8M A;  1WQU A;  1O4H A;  4NWF A;  1GRI A;  1SPR A;  3QWY A;  2HUW A;  2PLE A;  5DC0 B;  2IUI A;  3VS6 A;  2ETZ A;  3K2M A;  3HHM B;  5GJI A;  1UUS A;  2K79 B;  4LUD A;  2CS0 A;  4GL9 E;  1B47 A;  1RPY A;  1BMB A;  1LUI A;  1BHF A;  3IMJ A;  5I6V A;  1BLJ A;  1O4N A;  1D4T A;  3ZNI A;  1ZFP E;  2JYQ A;  5BO4 A;  1P13 A;  2FO0 A;  4K44 A;  2DX0 A;  1A1B A;  3VS0 A;  5AXI A;  2PTK A;  1LCJ A;  1X6C A;  1D4W A;  3S8L A;  3S9K A;  3N84 A;  3VS2 A;  2MRK A;  4D8K A;  2MRJ A;  2IZV A;  1I3Z A;  1O4Q A;  1YVH A;  3CWG A;  3PFV A;  4A4B A;  4F5B A;  4OHE A;  1BF5 A;  3GXW A;  1CWD L;  3GQI B;  1BLK A;  1MW4 A;  4TZI A;  5EHP A;  3OB2 B;  4K11 A;  4FL2 A;  3OV1 A;  2AOA A;  3VS4 A;  2RMX A;  1PIC A;  1O41 A;  1TZE E;  1XA6 A;  3VS3 A;  1TCE A;  1JYU A;  2PNB A;  1O45 A;  1O43 A;  1JWO A;  2DLZ A;  2YU7 A;  4OHL A;  4OHD A;  3BUW B;  1A81 A;  3VGO A;  2HDX A;  5GJH A;  1O4R A;  2EU0 A;  1O4I A;  1O4O A;  5HKY A;  1O4P A;  2FCI A;  1LKK A;  3M7F A;  1HCS B;  3OP0 A;  1NRV A;  4F5A A;  4E93 A;  1FBZ A;  1CSY A;  1HCT B;  1SHA A;  1O44 A;  3NHN A;  2EYV A;  4P9V A;  4XZ0 A;  3BUX B;  1O4M A;  1A1A A;  2SHP A;  4GPL B;  1JU5 A;  3VRO A;  1FYR A;  4WWQ A;  2OQ1 A;  1A1C A;  1O4G A;  1KSW A;  4F59 A;  3HCK A;  5HKZ A;  3OVE A;  4M4Z A;  2DLY A;  1O4L A;  3PS5 A;  1Z3K A;  1O49 A;  2C0I A;  4DGP A;  1MIL A;  2C0O A;  3CD3 A;  3TL0 A;  2CR4 A;  2C0T A;  3VS7 A;  2EKX A;  5EG3 B;  1JYR A;  1NZL A;  1SKJ A;  1LCK A;  3N7Y A;  4JGH A;  2L4K A;  1GHU A;  2EO6 A;  2GE9 A;  1AYC A;  4DGX A;  1LUK A;  3MXC A;  4U1P A;  1D1Z A;  1A08 A;  3VS1 A;  2K7A B;  2VIF A;  3PJP A;  1CWE A;  1FHS A;  1O4K A;  1UUR A;  2OZO A;  1O4C A;  4P9Z A;  5D0J A;  3VRY A;  2ABL A;  1QAD A;  3UYO A;  5EHR A;  1SPS A;  5CDW A;  2LNW A;  4JEG A;  1QCF A;  2RSY A;  2IUG A;  4OHH A;  1CSZ A;  2ROR A;  2Y1M A;  2Y3A B;  3PSJ A;  1R1S A;  3EAZ A;  1BHH A;  2HMH A;  3KFJ A;  1O42 A;  5HKW A;  2L6K A;  2Y1N A;  1G83 A;  1IS0 A;  1F1W A;  2ECD A;  5DC4 A;  1LKL A;  3VRZ A;  3IN8 A;  5DC9 A;  3BUM B;  3CXL A;  3WA4 A;  3VRN A;  1Y1U A;  1O48 A;  2QMS A;  3BKB A;  2MQI A;  1AOT F;  1R1Q A;  2PLD A;  3QWX X;  2EYY A;  1KA6 A;  1O46 A;  3MAZ A;  1NZV A;  1BFJ A;  2LCT A;  2H8H A;  4H1O A;  1AYB A;  4H34 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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