2AOBA

Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the grb2 sh2 domain
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
96
structure length
96
Chain Sequence
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 2
total genus 20
structure length 96
sequence length 96
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2005-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2aobA00
3CWGA 3GXWA 1AB2A 2BBUA 1JYQA 2CR4A 1SKJA 3GQIB 3PFVA 3CBLA 3VRYA 2LNXA 5I6VA 3VRZA 1O4GA 2AOAA 1FU6A 4QSYA 2C0IA 2EO3A 3K2MA 4A4BA 3TKZA 4NWFA 1O4EA 2PTKA 3CD3A 2ABLA 4JE4A 3GXXA 5DC0B 1O48A 1P13A 2OZOA 3PS5A 1BF5A 3UF4A 2DVJA 1BMBA 5EHRA 4TZIA 1O4KA 4EIHA 2EYVA 1SPRA 1AOTF 3EAZA 4EY0A 1QG1E 2C0TA 1CSYA 1BLKA 1XA6A 4XZ0A 1LUMA 2PNBA 2YU7A 3VS0A 4P9VA 3VS3A 4K45A 1BHHB 5GJIA 1M61A 4GPLB 1KA6A 3KFJA 2HUWA 1KC2A 1O4HA 2SRCA 1K9AA 3BUMB 2ECDA 1JU5A 1OO4A 4JEGA 3WA4A 1JYUA 3VRPA 1OO3A 1Z3KA 1SPSA 1O4OA 2L3TA 1AYAA 3VS2A 3IMDA 5IBMA 2H46E 3PLFB 1SHBA 3S9KA 2C9WA 1O4NA 1BG1A 4D8KA 4A4CA 1IJRA 3C7IA 3T04A 2LCTA 3MAZA 1F1WA 1RJAA 3OB2B 2HDVA 3NHNA 4M4ZA 1R1SA 4F5BA 3OV1A 1O46A 1D4WA 4LUDA 3VGOA 1AYDA 1O4CA 1TCEA 4OHDA 2EYYA 3HHMB 3IN8A 2K7AB 1O4BA 1FBZA 1JWOA 2EL8A 1X6CA 3S8NA 3BKBA 5DF6A 1BHFA 1LCJA 5D0JA 3MXCA 3QWYA 2RORA 1IS0A 2Y1MA 1QCFA 3PSKA 4L1BB 4H1OA 4GWFA 1UUSA 3US4A 2FCIA 1O4QA 1AYCA 2AOBA 5IBSA 5DC9A 1BFJA 2RVFA 2HMHA 4OHHA 1OPLA 1BM2A 1Y57A 2ETZA 1Y1UA 2OQ1A 2DLZA 2CI9A 3CXLA 1LUKA 1O4PA 3VROA 2H8HA 2DLYA 2IUGA 2L6KA 3PQZA 1O42A 2C0OA 1LUNA 2CBLA 2Y3AB 3BUXB 3N7YA 4FL3A 1O4AA 1O4JA 2MRKA 3M7FA 4E93A 1LKLA 3IMJA 1MILA 1O4FA 2CS0A 1FU5A 1O45A 3ZNIA 1G83A 1H9OA 1D1ZA 1B47A 4JGHA 2CI8A 5DC4A 2EU0A 1A1BA 1F2FA 4U1PA 2FO0A 1A1CA 2XP1A 4DGPA 1A1EA 5HKYA 2L4KA 1WQUA 1FBVA 3OB1B 1YVLA 4OHLA 3IN7A 1X0NA 2LQNA 2MK2A 3BUWB 3OVEA 5HKZA 1O41A 1HCTB 1O4MA 2RMXA 3TL0A 1LUIA 1FMKA 1NZLA 1CWDL 1NRVA 1RPYA 1O49A 2JYQA 5BO4A 1PICA 1BFIA 5J3XA 2GE9A 4K2RA 3VS4A 2EKXA 1I3ZA 4WWQA 1AOUF 5AXIA 3VS1A 2DX0A 1FHSA 2KK6A 3VS6A 5CDWA 1ZFPE 4FBNA 1R1PA 1O4LA 2K79B 4K44A 3N84A 2EO6A 1X27A 3HIZB 3PJPA 1A07A 4OHIA 1A81A 4XZ1A 3BUOB 1QADA 2HCKA 5EHPA 2RSYA 1YVHA 4P9ZA 1O4IA 2IUHA 3QWXX 1CWEA 1BLJA 5AULA 3UYOA 4F5AA 5HKWA 2EOBA 1AYBA 1OPKA 1FYRA 1NZVA 4GL9E 1O4DA 1O4RA 4E68A 1TZEE 2LNWA 1A09A 4FL2A 2PLDA 1D4TA 4LUEA 1RQQC 1A08A 1LKKA 2B3OA 2CRHA 2AUGA 3OP0A 1CSZA 1GHUA 5EEQA 2EYZA 2PNAA 3BUNB 3HCKA 1A1AA 2QMSA 1O44A 3N8MA 3VS5A 5KAZA 1UURA 5GJHA 5EG3B 1O43A 2H5KA 4DGXA 2PLEA 1HCSB 2DM0A 4OHEA 3VS7A 2SHPA 3MXYA 3PSJA 2KNOA 1BKMA 1R1QA 4NWGA 1JYRA 1BKLA 1SHDA 1M27A 1KA7A 1LCKA 2VIFA 1AD5A 3S8LA 1SHAA 2LQWA 2IUIA 4X6SA 4F59A 3EACA 3VRNA 2MRJA 2IZVA 1GRIA 1KSWA 3VRRA 2CIAA 2DCRA 2MQIA 2MC1A 4K11A 2YSXA 5EELA 3VRQA 1MW4A 2GSBA 2Y1NA 2HDXA 4ROJA 1BHHA 1CJ1A 3S8OA 4H34A 4U17A 1O47A
chains in the Genus database with same CATH superfamily
3CWGA 3GXWA 1AB2A 2BBUA 1JYQA 2CR4A 1SKJA 3GQIB 3PFVA 3CBLA 3VRYA 2LNXA 5I6VA 3VRZA 1O4GA 2AOAA 1FU6A 4QSYA 2C0IA 2EO3A 3K2MA 4A4BA 3TKZA 4NWFA 1O4EA 2PTKA 3CD3A 2ABLA 4JE4A 3GXXA 5DC0B 1O48A 1P13A 2OZOA 3PS5A 1BF5A 3UF4A 2DVJA 1BMBA 5EHRA 4TZIA 1O4KA 4EIHA 2EYVA 1SPRA 1AOTF 3EAZA 4EY0A 1QG1E 2C0TA 1CSYA 1BLKA 1XA6A 4XZ0A 1LUMA 2PNBA 2YU7A 3VS0A 4P9VA 3VS3A 4K45A 1BHHB 5GJIA 1M61A 4GPLB 1KA6A 3KFJA 2HUWA 1KC2A 1O4HA 2SRCA 1K9AA 3BUMB 2ECDA 1JU5A 1OO4A 4JEGA 3WA4A 1JYUA 3VRPA 1OO3A 1Z3KA 1SPSA 1O4OA 2L3TA 1AYAA 3VS2A 3IMDA 5IBMA 2H46E 3PLFB 1SHBA 3S9KA 2C9WA 1O4NA 1BG1A 4D8KA 4A4CA 1IJRA 3C7IA 3T04A 2LCTA 3MAZA 1F1WA 1RJAA 3OB2B 2HDVA 3NHNA 4M4ZA 1R1SA 4F5BA 3OV1A 1O46A 1D4WA 4LUDA 3VGOA 1AYDA 1O4CA 1TCEA 4OHDA 2EYYA 3HHMB 3IN8A 2K7AB 1O4BA 1FBZA 1JWOA 2EL8A 1X6CA 3S8NA 3BKBA 5DF6A 2LRAA 1BHFA 1LCJA 5D0JA 3MXCA 3QWYA 2RORA 1IS0A 2Y1MA 3K2TA 1QCFA 3PSKA 4L1BB 4H1OA 4GWFA 1UUSA 3US4A 2FCIA 1O4QA 1AYCA 2AOBA 5IBSA 5DC9A 1BFJA 2RVFA 2HMHA 4OHHA 1OPLA 1BM2A 1Y57A 2ETZA 1Y1UA 2OQ1A 2DLZA 2CI9A 3CXLA 1LUKA 1O4PA 3VROA 2H8HA 2DLYA 2IUGA 2L6KA 3PQZA 1O42A 2C0OA 1LUNA 2CBLA 2Y3AB 3BUXB 3N7YA 4FL3A 1O4AA 1O4JA 2MRKA 3M7FA 4E93A 1LKLA 3IMJA 1MILA 1O4FA 2CS0A 1FU5A 1O45A 3ZNIA 1G83A 1H9OA 1D1ZA 1B47A 4JGHA 2CI8A 5DC4A 2EU0A 1A1BA 1F2FA 4U1PA 2FO0A 1A1CA 2XP1A 4DGPA 1A1EA 5HKYA 2L4KA 1WQUA 1FBVA 3OB1B 1YVLA 4OHLA 3IN7A 1X0NA 2LQNA 2MK2A 3BUWB 3OVEA 5HKZA 1O41A 1HCTB 1O4MA 2RMXA 3TL0A 1LUIA 1FMKA 1NZLA 1CWDL 1NRVA 1RPYA 1O49A 2JYQA 5BO4A 1PICA 1BFIA 5J3XA 2GE9A 4K2RA 3VS4A 2EKXA 1I3ZA 4WWQA 1AOUF 5AXIA 3VS1A 2DX0A 1FHSA 2KK6A 3VS6A 5CDWA 1ZFPE 4FBNA 1R1PA 1O4LA 2K79B 4K44A 3N84A 2EO6A 1X27A 3HIZB 3PJPA 1A07A 4OHIA 1A81A 4XZ1A 3LYVA 3BUOB 1QADA 2HCKA 5EHPA 2RSYA 1YVHA 4P9ZA 1O4IA 2IUHA 3QWXX 1CWEA 1BLJA 5AULA 3UYOA 4F5AA 5HKWA 2EOBA 1AYBA 1OPKA 1FYRA 1NZVA 4GL9E 1O4DA 1O4RA 4E68A 1TZEE 2LNWA 1A09A 4FL2A 2PLDA 1D4TA 4LUEA 1RQQC 1A08A 1LKKA 2B3OA 2CRHA 2AUGA 3OP0A 1CSZA 1GHUA 5EEQA 2EYZA 2PNAA 3BUNB 3HCKA 1A1AA 2QMSA 1O44A 3N8MA 3VS5A 5KAZA 1UURA 5GJHA 5EG3B 1O43A 2H5KA 4DGXA 2PLEA 1HCSB 2DM0A 2KGYA 4OHEA 3VS7A 2SHPA 3MXYA 3PSJA 2KNOA 1BKMA 1R1QA 4NWGA 1JYRA 1BKLA 1SHDA 1M27A 1KA7A 1LCKA 2VIFA 1AD5A 3S8LA 1SHAA 2LQWA 2IUIA 4X6SA 4F59A 3EACA 3VRNA 2MRJA 2IZVA 1GRIA 1KSWA 3VRRA 2CIAA 2DCRA 2MQIA 2MC1A 4K11A 2YSXA 5EELA 3VRQA 1MW4A 2GSBA 2Y1NA 2HDXA 4ROJA 1BHHA 1CJ1A 3S8OA 4H34A 4U17A 1O47A
chains in the Genus database with same CATH topology
3CWGA 3GXWA 1AB2A 2BBUA 1JYQA 2CR4A 1SKJA 3GQIB 3PFVA 3CBLA 3VRYA 2LNXA 5I6VA 3VRZA 1O4GA 2AOAA 1FU6A 4QSYA 2C0IA 2EO3A 3K2MA 4A4BA 3TKZA 4NWFA 1O4EA 2PTKA 3CD3A 2ABLA 4JE4A 3GXXA 5DC0B 1O48A 1P13A 2OZOA 3PS5A 1BF5A 3UF4A 2DVJA 1BMBA 5EHRA 4TZIA 1O4KA 4EIHA 2EYVA 1SPRA 1AOTF 3EAZA 4EY0A 1QG1E 2C0TA 1CSYA 1BLKA 1XA6A 4XZ0A 1LUMA 2PNBA 2YU7A 3VS0A 4P9VA 3VS3A 4K45A 1BHHB 5GJIA 1M61A 4GPLB 1KA6A 3KFJA 2HUWA 1KC2A 1O4HA 2SRCA 1K9AA 3BUMB 2ECDA 1JU5A 1OO4A 4JEGA 3WA4A 1JYUA 3VRPA 1OO3A 1Z3KA 1SPSA 1O4OA 2L3TA 1AYAA 3VS2A 3IMDA 5IBMA 2H46E 3PLFB 1SHBA 3S9KA 2C9WA 1O4NA 1BG1A 4D8KA 4A4CA 1IJRA 3C7IA 3T04A 2LCTA 3MAZA 1F1WA 1RJAA 3OB2B 2HDVA 3NHNA 4M4ZA 1R1SA 4F5BA 3OV1A 1O46A 1D4WA 4LUDA 3VGOA 1AYDA 1O4CA 1TCEA 4OHDA 2EYYA 3HHMB 3IN8A 2K7AB 1O4BA 1FBZA 1JWOA 2EL8A 1X6CA 3S8NA 3BKBA 5DF6A 1BHFA 1LCJA 5D0JA 3MXCA 3QWYA 2RORA 1IS0A 2Y1MA 1QCFA 3PSKA 4L1BB 4H1OA 4GWFA 1UUSA 3US4A 2FCIA 1O4QA 1AYCA 2AOBA 5IBSA 5DC9A 1BFJA 2RVFA 2HMHA 4OHHA 1OPLA 1BM2A 1Y57A 2ETZA 1Y1UA 2OQ1A 2DLZA 2CI9A 3CXLA 1LUKA 1O4PA 3VROA 2H8HA 2DLYA 2IUGA 2L6KA 3PQZA 1O42A 2C0OA 1LUNA 2CBLA 2Y3AB 3BUXB 3N7YA 4FL3A 1O4AA 1O4JA 2MRKA 3M7FA 4E93A 1LKLA 3IMJA 1MILA 1O4FA 2CS0A 1FU5A 1O45A 3ZNIA 1G83A 1H9OA 1D1ZA 1B47A 4JGHA 2CI8A 5DC4A 2EU0A 1A1BA 1F2FA 4U1PA 2FO0A 1A1CA 2XP1A 4DGPA 1A1EA 5HKYA 2L4KA 1WQUA 1FBVA 3OB1B 1YVLA 4OHLA 3IN7A 1X0NA 2LQNA 2MK2A 3BUWB 3OVEA 5HKZA 1O41A 1HCTB 1O4MA 2RMXA 3TL0A 1LUIA 1FMKA 1NZLA 1CWDL 1NRVA 1RPYA 1O49A 2JYQA 5BO4A 1PICA 1BFIA 5J3XA 2GE9A 4K2RA 3VS4A 2EKXA 1I3ZA 4WWQA 1AOUF 5AXIA 3VS1A 2DX0A 1FHSA 2KK6A 3VS6A 5CDWA 1ZFPE 4FBNA 1R1PA 1O4LA 2K79B 4K44A 3N84A 2EO6A 1X27A 3HIZB 3PJPA 1A07A 4OHIA 1A81A 4XZ1A 3BUOB 1QADA 2HCKA 5EHPA 2RSYA 1YVHA 4P9ZA 1O4IA 2IUHA 3QWXX 1CWEA 1BLJA 5AULA 3UYOA 4F5AA 5HKWA 2EOBA 1AYBA 1OPKA 1FYRA 1NZVA 4GL9E 1O4DA 1O4RA 4E68A 1TZEE 2LNWA 1A09A 4FL2A 2PLDA 1D4TA 4LUEA 1RQQC 1A08A 1LKKA 2B3OA 2CRHA 2AUGA 3OP0A 1CSZA 1GHUA 5EEQA 2EYZA 2PNAA 3BUNB 3HCKA 1A1AA 2QMSA 1O44A 3N8MA 3VS5A 5KAZA 1UURA 5GJHA 5EG3B 1O43A 2H5KA 4DGXA 2PLEA 1HCSB 2DM0A 4OHEA 3VS7A 2SHPA 3MXYA 3PSJA 2KNOA 1BKMA 1R1QA 4NWGA 1JYRA 1BKLA 1SHDA 1M27A 1KA7A 1LCKA 2VIFA 1AD5A 3S8LA 1SHAA 2LQWA 2IUIA 4X6SA 4F59A 3EACA 3VRNA 2MRJA 2IZVA 1GRIA 1KSWA 3VRRA 2CIAA 2DCRA 2MQIA 2MC1A 4K11A 2YSXA 5EELA 3VRQA 1MW4A 2GSBA 2Y1NA 2HDXA 4ROJA 1BHHA 1CJ1A 3S8OA 4H34A 4U17A 1O47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CWG A;  3GXW A;  1AB2 A;  2BBU A;  1JYQ A;  2CR4 A;  1SKJ A;  3GQI B;  3PFV A;  3CBL A;  3VRY A;  2LNX A;  5I6V A;  3VRZ A;  1O4G A;  2AOA A;  1FU6 A;  4QSY A;  2C0I A;  2EO3 A;  3K2M A;  4A4B A;  3TKZ A;  4NWF A;  1O4E A;  2PTK A;  3CD3 A;  2ABL A;  4JE4 A;  3GXX A;  5DC0 B;  1O48 A;  1P13 A;  2OZO A;  3PS5 A;  1BF5 A;  3UF4 A;  2DVJ A;  1BMB A;  5EHR A;  4TZI A;  1O4K A;  4EIH A;  2EYV A;  1SPR A;  1AOT F;  3EAZ A;  4EY0 A;  1QG1 E;  2C0T A;  1CSY A;  1BLK A;  1XA6 A;  4XZ0 A;  1LUM A;  2PNB A;  2YU7 A;  3VS0 A;  4P9V A;  3VS3 A;  4K45 A;  1BHH B;  5GJI A;  1M61 A;  4GPL B;  1KA6 A;  3KFJ A;  2HUW A;  1KC2 A;  1O4H A;  2SRC A;  1K9A A;  3BUM B;  2ECD A;  1JU5 A;  1OO4 A;  4JEG A;  3WA4 A;  1JYU A;  3VRP A;  1OO3 A;  1Z3K A;  1SPS A;  1O4O A;  2L3T A;  1AYA A;  3VS2 A;  3IMD A;  5IBM A;  2H46 E;  3PLF B;  1SHB A;  3S9K A;  2C9W A;  1O4N A;  1BG1 A;  4D8K A;  4A4C A;  1IJR A;  3C7I A;  3T04 A;  2LCT A;  3MAZ A;  1F1W A;  1RJA A;  3OB2 B;  2HDV A;  3NHN A;  4M4Z A;  1R1S A;  4F5B A;  3OV1 A;  1O46 A;  1D4W A;  4LUD A;  3VGO A;  1AYD A;  1O4C A;  1TCE A;  4OHD A;  2EYY A;  3HHM B;  3IN8 A;  2K7A B;  1O4B A;  1FBZ A;  1JWO A;  2EL8 A;  1X6C A;  3S8N A;  3BKB A;  5DF6 A;  1BHF A;  1LCJ A;  5D0J A;  3MXC A;  3QWY A;  2ROR A;  1IS0 A;  2Y1M A;  1QCF A;  3PSK A;  4L1B B;  4H1O A;  4GWF A;  1UUS A;  3US4 A;  2FCI A;  1O4Q A;  1AYC A;  2AOB A;  5IBS A;  5DC9 A;  1BFJ A;  2RVF A;  2HMH A;  4OHH A;  1OPL A;  1BM2 A;  1Y57 A;  2ETZ A;  1Y1U A;  2OQ1 A;  2DLZ A;  2CI9 A;  3CXL A;  1LUK A;  1O4P A;  3VRO A;  2H8H A;  2DLY A;  2IUG A;  2L6K A;  3PQZ A;  1O42 A;  2C0O A;  1LUN A;  2CBL A;  2Y3A B;  3BUX B;  3N7Y A;  4FL3 A;  1O4A A;  1O4J A;  2MRK A;  3M7F A;  4E93 A;  1LKL A;  3IMJ A;  1MIL A;  1O4F A;  2CS0 A;  1FU5 A;  1O45 A;  3ZNI A;  1G83 A;  1H9O A;  1D1Z A;  1B47 A;  4JGH A;  2CI8 A;  5DC4 A;  2EU0 A;  1A1B A;  1F2F A;  4U1P A;  2FO0 A;  1A1C A;  2XP1 A;  4DGP A;  1A1E A;  5HKY A;  2L4K A;  1WQU A;  1FBV A;  3OB1 B;  1YVL A;  4OHL A;  3IN7 A;  1X0N A;  2LQN A;  2MK2 A;  3BUW B;  3OVE A;  5HKZ A;  1O41 A;  1HCT B;  1O4M A;  2RMX A;  3TL0 A;  1LUI A;  1FMK A;  1NZL A;  1CWD L;  1NRV A;  1RPY A;  1O49 A;  2JYQ A;  5BO4 A;  1PIC A;  1BFI A;  5J3X A;  2GE9 A;  4K2R A;  3VS4 A;  2EKX A;  1I3Z A;  4WWQ A;  1AOU F;  5AXI A;  3VS1 A;  2DX0 A;  1FHS A;  2KK6 A;  3VS6 A;  5CDW A;  1ZFP E;  4FBN A;  1R1P A;  1O4L A;  2K79 B;  4K44 A;  3N84 A;  2EO6 A;  1X27 A;  3HIZ B;  3PJP A;  1A07 A;  4OHI A;  1A81 A;  4XZ1 A;  3BUO B;  1QAD A;  2HCK A;  5EHP A;  2RSY A;  1YVH A;  4P9Z A;  1O4I A;  2IUH A;  3QWX X;  1CWE A;  1BLJ A;  5AUL A;  3UYO A;  4F5A A;  5HKW A;  2EOB A;  1AYB A;  1OPK A;  1FYR A;  1NZV A;  4GL9 E;  1O4D A;  1O4R A;  4E68 A;  1TZE E;  2LNW A;  1A09 A;  4FL2 A;  2PLD A;  1D4T A;  4LUE A;  1RQQ C;  1A08 A;  1LKK A;  2B3O A;  2CRH A;  2AUG A;  3OP0 A;  1CSZ A;  1GHU A;  5EEQ A;  2EYZ A;  2PNA A;  3BUN B;  3HCK A;  1A1A A;  2QMS A;  1O44 A;  3N8M A;  3VS5 A;  5KAZ A;  1UUR A;  5GJH A;  5EG3 B;  1O43 A;  2H5K A;  4DGX A;  2PLE A;  1HCS B;  2DM0 A;  4OHE A;  3VS7 A;  2SHP A;  3MXY A;  3PSJ A;  2KNO A;  1BKM A;  1R1Q A;  4NWG A;  1JYR A;  1BKL A;  1SHD A;  1M27 A;  1KA7 A;  1LCK A;  2VIF A;  1AD5 A;  3S8L A;  1SHA A;  2LQW A;  2IUI A;  4X6S A;  4F59 A;  3EAC A;  3VRN A;  2MRJ A;  2IZV A;  1GRI A;  1KSW A;  3VRR A;  2CIA A;  2DCR A;  2MQI A;  2MC1 A;  4K11 A;  2YSX A;  5EEL A;  3VRQ A;  1MW4 A;  2GSB A;  2Y1N A;  2HDX A;  4ROJ A;  1BHH A;  1CJ1 A;  3S8O A;  4H34 A;  4U17 A;  1O47 A; 
#chains in the Genus database with same CATH topology
 3CWG A;  3GXW A;  1AB2 A;  2BBU A;  1JYQ A;  2CR4 A;  1SKJ A;  3GQI B;  3PFV A;  3CBL A;  3VRY A;  2LNX A;  5I6V A;  3VRZ A;  1O4G A;  2AOA A;  1FU6 A;  4QSY A;  2C0I A;  2EO3 A;  3K2M A;  4A4B A;  3TKZ A;  4NWF A;  1O4E A;  2PTK A;  3CD3 A;  2ABL A;  4JE4 A;  3GXX A;  5DC0 B;  1O48 A;  1P13 A;  2OZO A;  3PS5 A;  1BF5 A;  3UF4 A;  2DVJ A;  1BMB A;  5EHR A;  4TZI A;  1O4K A;  4EIH A;  2EYV A;  1SPR A;  1AOT F;  3EAZ A;  4EY0 A;  1QG1 E;  2C0T A;  1CSY A;  1BLK A;  1XA6 A;  4XZ0 A;  1LUM A;  2PNB A;  2YU7 A;  3VS0 A;  4P9V A;  3VS3 A;  4K45 A;  1BHH B;  5GJI A;  1M61 A;  4GPL B;  1KA6 A;  3KFJ A;  2HUW A;  1KC2 A;  1O4H A;  2SRC A;  1K9A A;  3BUM B;  2ECD A;  1JU5 A;  1OO4 A;  4JEG A;  3WA4 A;  1JYU A;  3VRP A;  1OO3 A;  1Z3K A;  1SPS A;  1O4O A;  2L3T A;  1AYA A;  3VS2 A;  3IMD A;  5IBM A;  2H46 E;  3PLF B;  1SHB A;  3S9K A;  2C9W A;  1O4N A;  1BG1 A;  4D8K A;  4A4C A;  1IJR A;  3C7I A;  3T04 A;  2LCT A;  3MAZ A;  1F1W A;  1RJA A;  3OB2 B;  2HDV A;  3NHN A;  4M4Z A;  1R1S A;  4F5B A;  3OV1 A;  1O46 A;  1D4W A;  4LUD A;  3VGO A;  1AYD A;  1O4C A;  1TCE A;  4OHD A;  2EYY A;  3HHM B;  3IN8 A;  2K7A B;  1O4B A;  1FBZ A;  1JWO A;  2EL8 A;  1X6C A;  3S8N A;  3BKB A;  5DF6 A;  2LRA A;  1BHF A;  1LCJ A;  5D0J A;  3MXC A;  3QWY A;  2ROR A;  1IS0 A;  2Y1M A;  3K2T A;  1QCF A;  3PSK A;  4L1B B;  4H1O A;  4GWF A;  1UUS A;  3US4 A;  2FCI A;  1O4Q A;  1AYC A;  2AOB A;  5IBS A;  5DC9 A;  1BFJ A;  2RVF A;  2HMH A;  4OHH A;  1OPL A;  1BM2 A;  1Y57 A;  2ETZ A;  1Y1U A;  2OQ1 A;  2DLZ A;  2CI9 A;  3CXL A;  1LUK A;  1O4P A;  3VRO A;  2H8H A;  2DLY A;  2IUG A;  2L6K A;  3PQZ A;  1O42 A;  2C0O A;  1LUN A;  2CBL A;  2Y3A B;  3BUX B;  3N7Y A;  4FL3 A;  1O4A A;  1O4J A;  2MRK A;  3M7F A;  4E93 A;  1LKL A;  3IMJ A;  1MIL A;  1O4F A;  2CS0 A;  1FU5 A;  1O45 A;  3ZNI A;  1G83 A;  1H9O A;  1D1Z A;  1B47 A;  4JGH A;  2CI8 A;  5DC4 A;  2EU0 A;  1A1B A;  1F2F A;  4U1P A;  2FO0 A;  1A1C A;  2XP1 A;  4DGP A;  1A1E A;  5HKY A;  2L4K A;  1WQU A;  1FBV A;  3OB1 B;  1YVL A;  4OHL A;  3IN7 A;  1X0N A;  2LQN A;  2MK2 A;  3BUW B;  3OVE A;  5HKZ A;  1O41 A;  1HCT B;  1O4M A;  2RMX A;  3TL0 A;  1LUI A;  1FMK A;  1NZL A;  1CWD L;  1NRV A;  1RPY A;  1O49 A;  2JYQ A;  5BO4 A;  1PIC A;  1BFI A;  5J3X A;  2GE9 A;  4K2R A;  3VS4 A;  2EKX A;  1I3Z A;  4WWQ A;  1AOU F;  5AXI A;  3VS1 A;  2DX0 A;  1FHS A;  2KK6 A;  3VS6 A;  5CDW A;  1ZFP E;  4FBN A;  1R1P A;  1O4L A;  2K79 B;  4K44 A;  3N84 A;  2EO6 A;  1X27 A;  3HIZ B;  3PJP A;  1A07 A;  4OHI A;  1A81 A;  4XZ1 A;  3LYV A;  3BUO B;  1QAD A;  2HCK A;  5EHP A;  2RSY A;  1YVH A;  4P9Z A;  1O4I A;  2IUH A;  3QWX X;  1CWE A;  1BLJ A;  5AUL A;  3UYO A;  4F5A A;  5HKW A;  2EOB A;  1AYB A;  1OPK A;  1FYR A;  1NZV A;  4GL9 E;  1O4D A;  1O4R A;  4E68 A;  1TZE E;  2LNW A;  1A09 A;  4FL2 A;  2PLD A;  1D4T A;  4LUE A;  1RQQ C;  1A08 A;  1LKK A;  2B3O A;  2CRH A;  2AUG A;  3OP0 A;  1CSZ A;  1GHU A;  5EEQ A;  2EYZ A;  2PNA A;  3BUN B;  3HCK A;  1A1A A;  2QMS A;  1O44 A;  3N8M A;  3VS5 A;  5KAZ A;  1UUR A;  5GJH A;  5EG3 B;  1O43 A;  2H5K A;  4DGX A;  2PLE A;  1HCS B;  2DM0 A;  2KGY A;  4OHE A;  3VS7 A;  2SHP A;  3MXY A;  3PSJ A;  2KNO A;  1BKM A;  1R1Q A;  4NWG A;  1JYR A;  1BKL A;  1SHD A;  1M27 A;  1KA7 A;  1LCK A;  2VIF A;  1AD5 A;  3S8L A;  1SHA A;  2LQW A;  2IUI A;  4X6S A;  4F59 A;  3EAC A;  3VRN A;  2MRJ A;  2IZV A;  1GRI A;  1KSW A;  3VRR A;  2CIA A;  2DCR A;  2MQI A;  2MC1 A;  4K11 A;  2YSX A;  5EEL A;  3VRQ A;  1MW4 A;  2GSB A;  2Y1N A;  2HDX A;  4ROJ A;  1BHH A;  1CJ1 A;  3S8O A;  4H34 A;  4U17 A;  1O47 A; 
#chains in the Genus database with same CATH homology
 3CWG A;  3GXW A;  1AB2 A;  2BBU A;  1JYQ A;  2CR4 A;  1SKJ A;  3GQI B;  3PFV A;  3CBL A;  3VRY A;  2LNX A;  5I6V A;  3VRZ A;  1O4G A;  2AOA A;  1FU6 A;  4QSY A;  2C0I A;  2EO3 A;  3K2M A;  4A4B A;  3TKZ A;  4NWF A;  1O4E A;  2PTK A;  3CD3 A;  2ABL A;  4JE4 A;  3GXX A;  5DC0 B;  1O48 A;  1P13 A;  2OZO A;  3PS5 A;  1BF5 A;  3UF4 A;  2DVJ A;  1BMB A;  5EHR A;  4TZI A;  1O4K A;  4EIH A;  2EYV A;  1SPR A;  1AOT F;  3EAZ A;  4EY0 A;  1QG1 E;  2C0T A;  1CSY A;  1BLK A;  1XA6 A;  4XZ0 A;  1LUM A;  2PNB A;  2YU7 A;  3VS0 A;  4P9V A;  3VS3 A;  4K45 A;  1BHH B;  5GJI A;  1M61 A;  4GPL B;  1KA6 A;  3KFJ A;  2HUW A;  1KC2 A;  1O4H A;  2SRC A;  1K9A A;  3BUM B;  2ECD A;  1JU5 A;  1OO4 A;  4JEG A;  3WA4 A;  1JYU A;  3VRP A;  1OO3 A;  1Z3K A;  1SPS A;  1O4O A;  2L3T A;  1AYA A;  3VS2 A;  3IMD A;  5IBM A;  2H46 E;  3PLF B;  1SHB A;  3S9K A;  2C9W A;  1O4N A;  1BG1 A;  4D8K A;  4A4C A;  1IJR A;  3C7I A;  3T04 A;  2LCT A;  3MAZ A;  1F1W A;  1RJA A;  3OB2 B;  2HDV A;  3NHN A;  4M4Z A;  1R1S A;  4F5B A;  3OV1 A;  1O46 A;  1D4W A;  4LUD A;  3VGO A;  1AYD A;  1O4C A;  1TCE A;  4OHD A;  2EYY A;  3HHM B;  3IN8 A;  2K7A B;  1O4B A;  1FBZ A;  1JWO A;  2EL8 A;  1X6C A;  3S8N A;  3BKB A;  5DF6 A;  1BHF A;  1LCJ A;  5D0J A;  3MXC A;  3QWY A;  2ROR A;  1IS0 A;  2Y1M A;  1QCF A;  3PSK A;  4L1B B;  4H1O A;  4GWF A;  1UUS A;  3US4 A;  2FCI A;  1O4Q A;  1AYC A;  2AOB A;  5IBS A;  5DC9 A;  1BFJ A;  2RVF A;  2HMH A;  4OHH A;  1OPL A;  1BM2 A;  1Y57 A;  2ETZ A;  1Y1U A;  2OQ1 A;  2DLZ A;  2CI9 A;  3CXL A;  1LUK A;  1O4P A;  3VRO A;  2H8H A;  2DLY A;  2IUG A;  2L6K A;  3PQZ A;  1O42 A;  2C0O A;  1LUN A;  2CBL A;  2Y3A B;  3BUX B;  3N7Y A;  4FL3 A;  1O4A A;  1O4J A;  2MRK A;  3M7F A;  4E93 A;  1LKL A;  3IMJ A;  1MIL A;  1O4F A;  2CS0 A;  1FU5 A;  1O45 A;  3ZNI A;  1G83 A;  1H9O A;  1D1Z A;  1B47 A;  4JGH A;  2CI8 A;  5DC4 A;  2EU0 A;  1A1B A;  1F2F A;  4U1P A;  2FO0 A;  1A1C A;  2XP1 A;  4DGP A;  1A1E A;  5HKY A;  2L4K A;  1WQU A;  1FBV A;  3OB1 B;  1YVL A;  4OHL A;  3IN7 A;  1X0N A;  2LQN A;  2MK2 A;  3BUW B;  3OVE A;  5HKZ A;  1O41 A;  1HCT B;  1O4M A;  2RMX A;  3TL0 A;  1LUI A;  1FMK A;  1NZL A;  1CWD L;  1NRV A;  1RPY A;  1O49 A;  2JYQ A;  5BO4 A;  1PIC A;  1BFI A;  5J3X A;  2GE9 A;  4K2R A;  3VS4 A;  2EKX A;  1I3Z A;  4WWQ A;  1AOU F;  5AXI A;  3VS1 A;  2DX0 A;  1FHS A;  2KK6 A;  3VS6 A;  5CDW A;  1ZFP E;  4FBN A;  1R1P A;  1O4L A;  2K79 B;  4K44 A;  3N84 A;  2EO6 A;  1X27 A;  3HIZ B;  3PJP A;  1A07 A;  4OHI A;  1A81 A;  4XZ1 A;  3BUO B;  1QAD A;  2HCK A;  5EHP A;  2RSY A;  1YVH A;  4P9Z A;  1O4I A;  2IUH A;  3QWX X;  1CWE A;  1BLJ A;  5AUL A;  3UYO A;  4F5A A;  5HKW A;  2EOB A;  1AYB A;  1OPK A;  1FYR A;  1NZV A;  4GL9 E;  1O4D A;  1O4R A;  4E68 A;  1TZE E;  2LNW A;  1A09 A;  4FL2 A;  2PLD A;  1D4T A;  4LUE A;  1RQQ C;  1A08 A;  1LKK A;  2B3O A;  2CRH A;  2AUG A;  3OP0 A;  1CSZ A;  1GHU A;  5EEQ A;  2EYZ A;  2PNA A;  3BUN B;  3HCK A;  1A1A A;  2QMS A;  1O44 A;  3N8M A;  3VS5 A;  5KAZ A;  1UUR A;  5GJH A;  5EG3 B;  1O43 A;  2H5K A;  4DGX A;  2PLE A;  1HCS B;  2DM0 A;  4OHE A;  3VS7 A;  2SHP A;  3MXY A;  3PSJ A;  2KNO A;  1BKM A;  1R1Q A;  4NWG A;  1JYR A;  1BKL A;  1SHD A;  1M27 A;  1KA7 A;  1LCK A;  2VIF A;  1AD5 A;  3S8L A;  1SHA A;  2LQW A;  2IUI A;  4X6S A;  4F59 A;  3EAC A;  3VRN A;  2MRJ A;  2IZV A;  1GRI A;  1KSW A;  3VRR A;  2CIA A;  2DCR A;  2MQI A;  2MC1 A;  4K11 A;  2YSX A;  5EEL A;  3VRQ A;  1MW4 A;  2GSB A;  2Y1N A;  2HDX A;  4ROJ A;  1BHH A;  1CJ1 A;  3S8O A;  4H34 A;  4U17 A;  1O47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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