2H46E

Native domain-swapped dimer crystal structure of the grb2 sh2 domain
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
98
structure length
98
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and energetic aspects of Grb2-SH2 domain-swapping.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Growth Receptor Binding Protein 2
total genus 19
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2h46E00
3HIZB 2L4KA 2QMSA 3HCKA 1FMKA 1PICA 2PTKA 1O45A 3N84A 2C0OA 1BM2A 1O4RA 3PSJA 5HKYA 3MAZA 2IUIA 1O4KA 2PNAA 1KA6A 4U1PA 3OB1B 1O4JA 2DCRA 1WQUA 1D4TA 3BUMB 3IN7A 3VRQA 5DC4A 2EU0A 2EYYA 1BG1A 1CJ1A 2AOBA 4F5BA 2GE9A 2H5KA 2C0TA 3VRPA 3BUWB 1P13A 4JGHA 1O4EA 5HKWA 4H1OA 1A07A 1BFIA 5EHRA 3MXCA 2OQ1A 1AOUF 2L6KA 2CRHA 1A1CA 1BLKA 1BMBA 1O46A 3VS5A 2DLZA 1NZLA 4OHIA 3K2MA 4H34A 1NZVA 1A1EA 2EO3A 3VS4A 1R1SA 2AUGA 1AD5A 3QWYA 2B3OA 3C7IA 3VRYA 4EY0A 4K44A 4A4CA 1X0NA 1O4IA 1ZFPE 3VS3A 2OZOA 3KFJA 5IBSA 3VS1A 3GQIB 3BUNB 1CWDL 2EYZA 1F1WA 2DLYA 4EIHA 2GSBA 3BKBA 4GL9E 1SHAA 1O4CA 1KSWA 1SPRA 2CIAA 1BFJA 2LQWA 5DC0B 1SHBA 3OB2B 3VS6A 5EG3B 1SPSA 1O4FA 1TCEA 2MRKA 3PSKA 1HCTB 3T04A 1O4DA 1BF5A 2VIFA 2RVFA 3US4A 1HCSB 4GPLB 3S8LA 2HUWA 5EEQA 1BHFA 1LUIA 4D8KA 4OHLA 1Y57A 3CXLA 1JU5A 4JE4A 1AOTF 1BLJA 1UURA 1Z3KA 2HMHA 1A09A 2KK6A 5GJHA 4OHHA 2CR4A 2HDXA 3IMJA 1FHSA 2YU7A 2YSXA 3UYOA 2MRJA 2KNOA 2HCKA 5HKZA 5I6VA 4NWFA 2PNBA 2ETZA 1M27A 3GXWA 1AB2A 2MK2A 1A1AA 2SHPA 1SHDA 3PS5A 3N8MA 1RJAA 1CSZA 4F5AA 1O47A 2LNXA 1MILA 5DF6A 2EYVA 2EKXA 1D1ZA 3VGOA 2CI8A 2IUGA 5J3XA 2LCTA 3CWGA 1FBVA 1O48A 4DGPA 1BKLA 3ZNIA 4A4BA 3UF4A 3IMDA 1JYUA 5CDWA 3PFVA 1AYDA 2LQNA 1JYQA 3S8OA 2H8HA 3VROA 4ROJA 1O4LA 1FYRA 5AULA 1H9OA 1A08A 1CSYA 2Y1MA 2IUHA 3VS0A 1BKMA 1XA6A 3VS7A 1G83A 4P9VA 1R1QA 1M61A 1O4QA 4TZIA 2FO0A 4OHEA 2C9WA 1KA7A 2XP1A 2DVJA 1FBZA 4WWQA 3IN8A 5BO4A 1GHUA 3M7FA 1O4OA 2C0IA 1D4WA 1LUNA 2EL8A 2ABLA 3N7YA 4U17A 1RQQC 1QG1E 1R1PA 1SKJA 3CBLA 4DGXA 1O4HA 1LCJA 4E68A 1QCFA 3EAZA 2DM0A 1F2FA 4FL3A 2ECDA 1I3ZA 2RMXA 5EELA 4X6SA 1B47A 1FU5A 5AXIA 1A1BA 3PJPA 3BUOB 1JWOA 1OO3A 2FCIA 2H46E 1QADA 3HHMB 5D0JA 1BHHB 4JEGA 4E93A 3PQZA 2PLDA 1O43A 1MW4A 2EO6A 4FL2A 1AYCA 5KAZA 2SRCA 2K79B 5IBMA 2MC1A 1Y1UA 1UUSA 2RSYA 2PLEA 3NHNA 2JYQA 4K11A 1AYBA 2K7AB 3S8NA 3QWXX 1RPYA 2HDVA 1LKLA 1O41A 4OHDA 5GJIA 4LUEA 1O49A 4FBNA 1K9AA 2BBUA 3EACA 3PLFB 1O4GA 2EOBA 1LUKA 3VRRA 5EHPA 4GWFA 1O4PA 1AYAA 1O44A 1O4NA 2MQIA 1KC2A 1JYRA 1O4BA 2CS0A 3S9KA 4M4ZA 2DX0A 3TKZA 2AOAA 1YVHA 1LUMA 1OPKA 3GXXA 3BUXB 2LNWA 3WA4A 4NWGA 3OP0A 1O4MA 3OVEA 4XZ1A 3VRNA 1O42A 1IS0A 1IJRA 2Y3AB 2L3TA 1OPLA 2RORA 1GRIA 1NRVA 3MXYA 2Y1NA 3VS2A 2CI9A 1LKKA 3TL0A 1X27A 1X6CA 4LUDA 3CD3A 1LCKA 1CWEA 2CBLA 1YVLA 2IZVA 5DC9A 4XZ0A 1O4AA 1BHHA 4QSYA 1A81A 1FU6A 1TZEE 4K2RA 4P9ZA 3OV1A 3VRZA 4F59A 1OO4A 4K45A 4L1BB
chains in the Genus database with same CATH superfamily
3HIZB 2L4KA 2QMSA 3HCKA 1FMKA 1PICA 2PTKA 1O45A 3N84A 2C0OA 1BM2A 1O4RA 3PSJA 5HKYA 3MAZA 2IUIA 2LRAA 1O4KA 2PNAA 1KA6A 4U1PA 3OB1B 1O4JA 2DCRA 1WQUA 1D4TA 3BUMB 3IN7A 3VRQA 5DC4A 2EU0A 2EYYA 1BG1A 1CJ1A 2AOBA 4F5BA 2GE9A 2H5KA 2C0TA 3VRPA 3BUWB 1P13A 4JGHA 1O4EA 5HKWA 4H1OA 1A07A 1BFIA 5EHRA 3MXCA 2OQ1A 2KGYA 1AOUF 2L6KA 2CRHA 1A1CA 1BLKA 1BMBA 1O46A 3VS5A 2DLZA 1NZLA 4OHIA 3K2MA 4H34A 1NZVA 1A1EA 2EO3A 3VS4A 1R1SA 2AUGA 1AD5A 3QWYA 2B3OA 3C7IA 3VRYA 4EY0A 4K44A 4A4CA 1X0NA 1O4IA 1ZFPE 3VS3A 2OZOA 3KFJA 5IBSA 3VS1A 3GQIB 3BUNB 1CWDL 2EYZA 1F1WA 2DLYA 4EIHA 2GSBA 3BKBA 4GL9E 1SHAA 1O4CA 1KSWA 1SPRA 2CIAA 1BFJA 2LQWA 5DC0B 1SHBA 3OB2B 3VS6A 5EG3B 1SPSA 1O4FA 1TCEA 2MRKA 3PSKA 1HCTB 3T04A 1O4DA 1BF5A 2VIFA 2RVFA 3US4A 1HCSB 4GPLB 3S8LA 2HUWA 5EEQA 1BHFA 1LUIA 4D8KA 4OHLA 1Y57A 3CXLA 1JU5A 4JE4A 1AOTF 1BLJA 1UURA 1Z3KA 2HMHA 1A09A 2KK6A 5GJHA 4OHHA 2CR4A 2HDXA 3IMJA 1FHSA 2YU7A 2YSXA 3UYOA 2MRJA 2KNOA 2HCKA 5HKZA 5I6VA 4NWFA 2PNBA 2ETZA 1M27A 3GXWA 1AB2A 2MK2A 1A1AA 2SHPA 1SHDA 3PS5A 3N8MA 1RJAA 1CSZA 4F5AA 1O47A 2LNXA 1MILA 5DF6A 2EYVA 2EKXA 1D1ZA 3VGOA 2CI8A 2IUGA 5J3XA 2LCTA 3CWGA 1FBVA 1O48A 4DGPA 1BKLA 3ZNIA 4A4BA 3UF4A 3IMDA 1JYUA 5CDWA 3PFVA 1AYDA 2LQNA 1JYQA 3S8OA 2H8HA 3VROA 4ROJA 1O4LA 1FYRA 5AULA 1H9OA 3K2TA 1A08A 1CSYA 2Y1MA 2IUHA 3VS0A 1BKMA 1XA6A 3VS7A 1G83A 4P9VA 1R1QA 1M61A 1O4QA 4TZIA 2FO0A 4OHEA 2C9WA 1KA7A 2XP1A 2DVJA 1FBZA 4WWQA 3IN8A 5BO4A 1GHUA 3M7FA 1O4OA 2C0IA 1D4WA 1LUNA 2EL8A 2ABLA 3N7YA 4U17A 1RQQC 1QG1E 1R1PA 1SKJA 3CBLA 4DGXA 1O4HA 1LCJA 4E68A 1QCFA 3EAZA 2DM0A 1F2FA 4FL3A 2ECDA 1I3ZA 2RMXA 5EELA 4X6SA 1B47A 1FU5A 5AXIA 1A1BA 3PJPA 3BUOB 1JWOA 1OO3A 2FCIA 2H46E 1QADA 3HHMB 5D0JA 1BHHB 4JEGA 4E93A 3PQZA 2PLDA 1O43A 1MW4A 2EO6A 4FL2A 1AYCA 5KAZA 2SRCA 2K79B 5IBMA 2MC1A 1Y1UA 1UUSA 2RSYA 2PLEA 3NHNA 2JYQA 4K11A 1AYBA 2K7AB 3S8NA 3QWXX 1RPYA 2HDVA 1LKLA 1O41A 4OHDA 5GJIA 4LUEA 1O49A 4FBNA 1K9AA 2BBUA 3EACA 3PLFB 1O4GA 2EOBA 1LUKA 3VRRA 5EHPA 4GWFA 1O4PA 3LYVA 1AYAA 1O44A 1O4NA 2MQIA 1KC2A 1JYRA 1O4BA 2CS0A 3S9KA 4M4ZA 2DX0A 3TKZA 2AOAA 1YVHA 1LUMA 1OPKA 3GXXA 3BUXB 2LNWA 3WA4A 4NWGA 3OP0A 1O4MA 3OVEA 4XZ1A 3VRNA 1O42A 1IS0A 1IJRA 2Y3AB 2L3TA 1OPLA 2RORA 1GRIA 1NRVA 3MXYA 2Y1NA 3VS2A 2CI9A 1LKKA 3TL0A 1X27A 1X6CA 4LUDA 3CD3A 1LCKA 1CWEA 2CBLA 1YVLA 2IZVA 5DC9A 4XZ0A 1O4AA 1BHHA 4QSYA 1A81A 1FU6A 1TZEE 4K2RA 4P9ZA 3OV1A 3VRZA 4F59A 1OO4A 4K45A 4L1BB
chains in the Genus database with same CATH topology
3HIZB 2L4KA 2QMSA 3HCKA 1FMKA 1PICA 2PTKA 1O45A 3N84A 2C0OA 1BM2A 1O4RA 3PSJA 5HKYA 3MAZA 2IUIA 1O4KA 2PNAA 1KA6A 4U1PA 3OB1B 1O4JA 2DCRA 1WQUA 1D4TA 3BUMB 3IN7A 3VRQA 5DC4A 2EU0A 2EYYA 1BG1A 1CJ1A 2AOBA 4F5BA 2GE9A 2H5KA 2C0TA 3VRPA 3BUWB 1P13A 4JGHA 1O4EA 5HKWA 4H1OA 1A07A 1BFIA 5EHRA 3MXCA 2OQ1A 1AOUF 2L6KA 2CRHA 1A1CA 1BLKA 1BMBA 1O46A 3VS5A 2DLZA 1NZLA 4OHIA 3K2MA 4H34A 1NZVA 1A1EA 2EO3A 3VS4A 1R1SA 2AUGA 1AD5A 3QWYA 2B3OA 3C7IA 3VRYA 4EY0A 4K44A 4A4CA 1X0NA 1O4IA 1ZFPE 3VS3A 2OZOA 3KFJA 5IBSA 3VS1A 3GQIB 3BUNB 1CWDL 2EYZA 1F1WA 2DLYA 4EIHA 2GSBA 3BKBA 4GL9E 1SHAA 1O4CA 1KSWA 1SPRA 2CIAA 1BFJA 2LQWA 5DC0B 1SHBA 3OB2B 3VS6A 5EG3B 1SPSA 1O4FA 1TCEA 2MRKA 3PSKA 1HCTB 3T04A 1O4DA 1BF5A 2VIFA 2RVFA 3US4A 1HCSB 4GPLB 3S8LA 2HUWA 5EEQA 1BHFA 1LUIA 4D8KA 4OHLA 1Y57A 3CXLA 1JU5A 4JE4A 1AOTF 1BLJA 1UURA 1Z3KA 2HMHA 1A09A 2KK6A 5GJHA 4OHHA 2CR4A 2HDXA 3IMJA 1FHSA 2YU7A 2YSXA 3UYOA 2MRJA 2KNOA 2HCKA 5HKZA 5I6VA 4NWFA 2PNBA 2ETZA 1M27A 3GXWA 1AB2A 2MK2A 1A1AA 2SHPA 1SHDA 3PS5A 3N8MA 1RJAA 1CSZA 4F5AA 1O47A 2LNXA 1MILA 5DF6A 2EYVA 2EKXA 1D1ZA 3VGOA 2CI8A 2IUGA 5J3XA 2LCTA 3CWGA 1FBVA 1O48A 4DGPA 1BKLA 3ZNIA 4A4BA 3UF4A 3IMDA 1JYUA 5CDWA 3PFVA 1AYDA 2LQNA 1JYQA 3S8OA 2H8HA 3VROA 4ROJA 1O4LA 1FYRA 5AULA 1H9OA 1A08A 1CSYA 2Y1MA 2IUHA 3VS0A 1BKMA 1XA6A 3VS7A 1G83A 4P9VA 1R1QA 1M61A 1O4QA 4TZIA 2FO0A 4OHEA 2C9WA 1KA7A 2XP1A 2DVJA 1FBZA 4WWQA 3IN8A 5BO4A 1GHUA 3M7FA 1O4OA 2C0IA 1D4WA 1LUNA 2EL8A 2ABLA 3N7YA 4U17A 1RQQC 1QG1E 1R1PA 1SKJA 3CBLA 4DGXA 1O4HA 1LCJA 4E68A 1QCFA 3EAZA 2DM0A 1F2FA 4FL3A 2ECDA 1I3ZA 2RMXA 5EELA 4X6SA 1B47A 1FU5A 5AXIA 1A1BA 3PJPA 3BUOB 1JWOA 1OO3A 2FCIA 2H46E 1QADA 3HHMB 5D0JA 1BHHB 4JEGA 4E93A 3PQZA 2PLDA 1O43A 1MW4A 2EO6A 4FL2A 1AYCA 5KAZA 2SRCA 2K79B 5IBMA 2MC1A 1Y1UA 1UUSA 2RSYA 2PLEA 3NHNA 2JYQA 4K11A 1AYBA 2K7AB 3S8NA 3QWXX 1RPYA 2HDVA 1LKLA 1O41A 4OHDA 5GJIA 4LUEA 1O49A 4FBNA 1K9AA 2BBUA 3EACA 3PLFB 1O4GA 2EOBA 1LUKA 3VRRA 5EHPA 4GWFA 1O4PA 1AYAA 1O44A 1O4NA 2MQIA 1KC2A 1JYRA 1O4BA 2CS0A 3S9KA 4M4ZA 2DX0A 3TKZA 2AOAA 1YVHA 1LUMA 1OPKA 3GXXA 3BUXB 2LNWA 3WA4A 4NWGA 3OP0A 1O4MA 3OVEA 4XZ1A 3VRNA 1O42A 1IS0A 1IJRA 2Y3AB 2L3TA 1OPLA 2RORA 1GRIA 1NRVA 3MXYA 2Y1NA 3VS2A 2CI9A 1LKKA 3TL0A 1X27A 1X6CA 4LUDA 3CD3A 1LCKA 1CWEA 2CBLA 1YVLA 2IZVA 5DC9A 4XZ0A 1O4AA 1BHHA 4QSYA 1A81A 1FU6A 1TZEE 4K2RA 4P9ZA 3OV1A 3VRZA 4F59A 1OO4A 4K45A 4L1BB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HIZ B;  2L4K A;  2QMS A;  3HCK A;  1FMK A;  1PIC A;  2PTK A;  1O45 A;  3N84 A;  2C0O A;  1BM2 A;  1O4R A;  3PSJ A;  5HKY A;  3MAZ A;  2IUI A;  1O4K A;  2PNA A;  1KA6 A;  4U1P A;  3OB1 B;  1O4J A;  2DCR A;  1WQU A;  1D4T A;  3BUM B;  3IN7 A;  3VRQ A;  5DC4 A;  2EU0 A;  2EYY A;  1BG1 A;  1CJ1 A;  2AOB A;  4F5B A;  2GE9 A;  2H5K A;  2C0T A;  3VRP A;  3BUW B;  1P13 A;  4JGH A;  1O4E A;  5HKW A;  4H1O A;  1A07 A;  1BFI A;  5EHR A;  3MXC A;  2OQ1 A;  1AOU F;  2L6K A;  2CRH A;  1A1C A;  1BLK A;  1BMB A;  1O46 A;  3VS5 A;  2DLZ A;  1NZL A;  4OHI A;  3K2M A;  4H34 A;  1NZV A;  1A1E A;  2EO3 A;  3VS4 A;  1R1S A;  2AUG A;  1AD5 A;  3QWY A;  2B3O A;  3C7I A;  3VRY A;  4EY0 A;  4K44 A;  4A4C A;  1X0N A;  1O4I A;  1ZFP E;  3VS3 A;  2OZO A;  3KFJ A;  5IBS A;  3VS1 A;  3GQI B;  3BUN B;  1CWD L;  2EYZ A;  1F1W A;  2DLY A;  4EIH A;  2GSB A;  3BKB A;  4GL9 E;  1SHA A;  1O4C A;  1KSW A;  1SPR A;  2CIA A;  1BFJ A;  2LQW A;  5DC0 B;  1SHB A;  3OB2 B;  3VS6 A;  5EG3 B;  1SPS A;  1O4F A;  1TCE A;  2MRK A;  3PSK A;  1HCT B;  3T04 A;  1O4D A;  1BF5 A;  2VIF A;  2RVF A;  3US4 A;  1HCS B;  4GPL B;  3S8L A;  2HUW A;  5EEQ A;  1BHF A;  1LUI A;  4D8K A;  4OHL A;  1Y57 A;  3CXL A;  1JU5 A;  4JE4 A;  1AOT F;  1BLJ A;  1UUR A;  1Z3K A;  2HMH A;  1A09 A;  2KK6 A;  5GJH A;  4OHH A;  2CR4 A;  2HDX A;  3IMJ A;  1FHS A;  2YU7 A;  2YSX A;  3UYO A;  2MRJ A;  2KNO A;  2HCK A;  5HKZ A;  5I6V A;  4NWF A;  2PNB A;  2ETZ A;  1M27 A;  3GXW A;  1AB2 A;  2MK2 A;  1A1A A;  2SHP A;  1SHD A;  3PS5 A;  3N8M A;  1RJA A;  1CSZ A;  4F5A A;  1O47 A;  2LNX A;  1MIL A;  5DF6 A;  2EYV A;  2EKX A;  1D1Z A;  3VGO A;  2CI8 A;  2IUG A;  5J3X A;  2LCT A;  3CWG A;  1FBV A;  1O48 A;  4DGP A;  1BKL A;  3ZNI A;  4A4B A;  3UF4 A;  3IMD A;  1JYU A;  5CDW A;  3PFV A;  1AYD A;  2LQN A;  1JYQ A;  3S8O A;  2H8H A;  3VRO A;  4ROJ A;  1O4L A;  1FYR A;  5AUL A;  1H9O A;  1A08 A;  1CSY A;  2Y1M A;  2IUH A;  3VS0 A;  1BKM A;  1XA6 A;  3VS7 A;  1G83 A;  4P9V A;  1R1Q A;  1M61 A;  1O4Q A;  4TZI A;  2FO0 A;  4OHE A;  2C9W A;  1KA7 A;  2XP1 A;  2DVJ A;  1FBZ A;  4WWQ A;  3IN8 A;  5BO4 A;  1GHU A;  3M7F A;  1O4O A;  2C0I A;  1D4W A;  1LUN A;  2EL8 A;  2ABL A;  3N7Y A;  4U17 A;  1RQQ C;  1QG1 E;  1R1P A;  1SKJ A;  3CBL A;  4DGX A;  1O4H A;  1LCJ A;  4E68 A;  1QCF A;  3EAZ A;  2DM0 A;  1F2F A;  4FL3 A;  2ECD A;  1I3Z A;  2RMX A;  5EEL A;  4X6S A;  1B47 A;  1FU5 A;  5AXI A;  1A1B A;  3PJP A;  3BUO B;  1JWO A;  1OO3 A;  2FCI A;  2H46 E;  1QAD A;  3HHM B;  5D0J A;  1BHH B;  4JEG A;  4E93 A;  3PQZ A;  2PLD A;  1O43 A;  1MW4 A;  2EO6 A;  4FL2 A;  1AYC A;  5KAZ A;  2SRC A;  2K79 B;  5IBM A;  2MC1 A;  1Y1U A;  1UUS A;  2RSY A;  2PLE A;  3NHN A;  2JYQ A;  4K11 A;  1AYB A;  2K7A B;  3S8N A;  3QWX X;  1RPY A;  2HDV A;  1LKL A;  1O41 A;  4OHD A;  5GJI A;  4LUE A;  1O49 A;  4FBN A;  1K9A A;  2BBU A;  3EAC A;  3PLF B;  1O4G A;  2EOB A;  1LUK A;  3VRR A;  5EHP A;  4GWF A;  1O4P A;  1AYA A;  1O44 A;  1O4N A;  2MQI A;  1KC2 A;  1JYR A;  1O4B A;  2CS0 A;  3S9K A;  4M4Z A;  2DX0 A;  3TKZ A;  2AOA A;  1YVH A;  1LUM A;  1OPK A;  3GXX A;  3BUX B;  2LNW A;  3WA4 A;  4NWG A;  3OP0 A;  1O4M A;  3OVE A;  4XZ1 A;  3VRN A;  1O42 A;  1IS0 A;  1IJR A;  2Y3A B;  2L3T A;  1OPL A;  2ROR A;  1GRI A;  1NRV A;  3MXY A;  2Y1N A;  3VS2 A;  2CI9 A;  1LKK A;  3TL0 A;  1X27 A;  1X6C A;  4LUD A;  3CD3 A;  1LCK A;  1CWE A;  2CBL A;  1YVL A;  2IZV A;  5DC9 A;  4XZ0 A;  1O4A A;  1BHH A;  4QSY A;  1A81 A;  1FU6 A;  1TZE E;  4K2R A;  4P9Z A;  3OV1 A;  3VRZ A;  4F59 A;  1OO4 A;  4K45 A;  4L1B B; 
#chains in the Genus database with same CATH topology
 3HIZ B;  2L4K A;  2QMS A;  3HCK A;  1FMK A;  1PIC A;  2PTK A;  1O45 A;  3N84 A;  2C0O A;  1BM2 A;  1O4R A;  3PSJ A;  5HKY A;  3MAZ A;  2IUI A;  2LRA A;  1O4K A;  2PNA A;  1KA6 A;  4U1P A;  3OB1 B;  1O4J A;  2DCR A;  1WQU A;  1D4T A;  3BUM B;  3IN7 A;  3VRQ A;  5DC4 A;  2EU0 A;  2EYY A;  1BG1 A;  1CJ1 A;  2AOB A;  4F5B A;  2GE9 A;  2H5K A;  2C0T A;  3VRP A;  3BUW B;  1P13 A;  4JGH A;  1O4E A;  5HKW A;  4H1O A;  1A07 A;  1BFI A;  5EHR A;  3MXC A;  2OQ1 A;  2KGY A;  1AOU F;  2L6K A;  2CRH A;  1A1C A;  1BLK A;  1BMB A;  1O46 A;  3VS5 A;  2DLZ A;  1NZL A;  4OHI A;  3K2M A;  4H34 A;  1NZV A;  1A1E A;  2EO3 A;  3VS4 A;  1R1S A;  2AUG A;  1AD5 A;  3QWY A;  2B3O A;  3C7I A;  3VRY A;  4EY0 A;  4K44 A;  4A4C A;  1X0N A;  1O4I A;  1ZFP E;  3VS3 A;  2OZO A;  3KFJ A;  5IBS A;  3VS1 A;  3GQI B;  3BUN B;  1CWD L;  2EYZ A;  1F1W A;  2DLY A;  4EIH A;  2GSB A;  3BKB A;  4GL9 E;  1SHA A;  1O4C A;  1KSW A;  1SPR A;  2CIA A;  1BFJ A;  2LQW A;  5DC0 B;  1SHB A;  3OB2 B;  3VS6 A;  5EG3 B;  1SPS A;  1O4F A;  1TCE A;  2MRK A;  3PSK A;  1HCT B;  3T04 A;  1O4D A;  1BF5 A;  2VIF A;  2RVF A;  3US4 A;  1HCS B;  4GPL B;  3S8L A;  2HUW A;  5EEQ A;  1BHF A;  1LUI A;  4D8K A;  4OHL A;  1Y57 A;  3CXL A;  1JU5 A;  4JE4 A;  1AOT F;  1BLJ A;  1UUR A;  1Z3K A;  2HMH A;  1A09 A;  2KK6 A;  5GJH A;  4OHH A;  2CR4 A;  2HDX A;  3IMJ A;  1FHS A;  2YU7 A;  2YSX A;  3UYO A;  2MRJ A;  2KNO A;  2HCK A;  5HKZ A;  5I6V A;  4NWF A;  2PNB A;  2ETZ A;  1M27 A;  3GXW A;  1AB2 A;  2MK2 A;  1A1A A;  2SHP A;  1SHD A;  3PS5 A;  3N8M A;  1RJA A;  1CSZ A;  4F5A A;  1O47 A;  2LNX A;  1MIL A;  5DF6 A;  2EYV A;  2EKX A;  1D1Z A;  3VGO A;  2CI8 A;  2IUG A;  5J3X A;  2LCT A;  3CWG A;  1FBV A;  1O48 A;  4DGP A;  1BKL A;  3ZNI A;  4A4B A;  3UF4 A;  3IMD A;  1JYU A;  5CDW A;  3PFV A;  1AYD A;  2LQN A;  1JYQ A;  3S8O A;  2H8H A;  3VRO A;  4ROJ A;  1O4L A;  1FYR A;  5AUL A;  1H9O A;  3K2T A;  1A08 A;  1CSY A;  2Y1M A;  2IUH A;  3VS0 A;  1BKM A;  1XA6 A;  3VS7 A;  1G83 A;  4P9V A;  1R1Q A;  1M61 A;  1O4Q A;  4TZI A;  2FO0 A;  4OHE A;  2C9W A;  1KA7 A;  2XP1 A;  2DVJ A;  1FBZ A;  4WWQ A;  3IN8 A;  5BO4 A;  1GHU A;  3M7F A;  1O4O A;  2C0I A;  1D4W A;  1LUN A;  2EL8 A;  2ABL A;  3N7Y A;  4U17 A;  1RQQ C;  1QG1 E;  1R1P A;  1SKJ A;  3CBL A;  4DGX A;  1O4H A;  1LCJ A;  4E68 A;  1QCF A;  3EAZ A;  2DM0 A;  1F2F A;  4FL3 A;  2ECD A;  1I3Z A;  2RMX A;  5EEL A;  4X6S A;  1B47 A;  1FU5 A;  5AXI A;  1A1B A;  3PJP A;  3BUO B;  1JWO A;  1OO3 A;  2FCI A;  2H46 E;  1QAD A;  3HHM B;  5D0J A;  1BHH B;  4JEG A;  4E93 A;  3PQZ A;  2PLD A;  1O43 A;  1MW4 A;  2EO6 A;  4FL2 A;  1AYC A;  5KAZ A;  2SRC A;  2K79 B;  5IBM A;  2MC1 A;  1Y1U A;  1UUS A;  2RSY A;  2PLE A;  3NHN A;  2JYQ A;  4K11 A;  1AYB A;  2K7A B;  3S8N A;  3QWX X;  1RPY A;  2HDV A;  1LKL A;  1O41 A;  4OHD A;  5GJI A;  4LUE A;  1O49 A;  4FBN A;  1K9A A;  2BBU A;  3EAC A;  3PLF B;  1O4G A;  2EOB A;  1LUK A;  3VRR A;  5EHP A;  4GWF A;  1O4P A;  3LYV A;  1AYA A;  1O44 A;  1O4N A;  2MQI A;  1KC2 A;  1JYR A;  1O4B A;  2CS0 A;  3S9K A;  4M4Z A;  2DX0 A;  3TKZ A;  2AOA A;  1YVH A;  1LUM A;  1OPK A;  3GXX A;  3BUX B;  2LNW A;  3WA4 A;  4NWG A;  3OP0 A;  1O4M A;  3OVE A;  4XZ1 A;  3VRN A;  1O42 A;  1IS0 A;  1IJR A;  2Y3A B;  2L3T A;  1OPL A;  2ROR A;  1GRI A;  1NRV A;  3MXY A;  2Y1N A;  3VS2 A;  2CI9 A;  1LKK A;  3TL0 A;  1X27 A;  1X6C A;  4LUD A;  3CD3 A;  1LCK A;  1CWE A;  2CBL A;  1YVL A;  2IZV A;  5DC9 A;  4XZ0 A;  1O4A A;  1BHH A;  4QSY A;  1A81 A;  1FU6 A;  1TZE E;  4K2R A;  4P9Z A;  3OV1 A;  3VRZ A;  4F59 A;  1OO4 A;  4K45 A;  4L1B B; 
#chains in the Genus database with same CATH homology
 3HIZ B;  2L4K A;  2QMS A;  3HCK A;  1FMK A;  1PIC A;  2PTK A;  1O45 A;  3N84 A;  2C0O A;  1BM2 A;  1O4R A;  3PSJ A;  5HKY A;  3MAZ A;  2IUI A;  1O4K A;  2PNA A;  1KA6 A;  4U1P A;  3OB1 B;  1O4J A;  2DCR A;  1WQU A;  1D4T A;  3BUM B;  3IN7 A;  3VRQ A;  5DC4 A;  2EU0 A;  2EYY A;  1BG1 A;  1CJ1 A;  2AOB A;  4F5B A;  2GE9 A;  2H5K A;  2C0T A;  3VRP A;  3BUW B;  1P13 A;  4JGH A;  1O4E A;  5HKW A;  4H1O A;  1A07 A;  1BFI A;  5EHR A;  3MXC A;  2OQ1 A;  1AOU F;  2L6K A;  2CRH A;  1A1C A;  1BLK A;  1BMB A;  1O46 A;  3VS5 A;  2DLZ A;  1NZL A;  4OHI A;  3K2M A;  4H34 A;  1NZV A;  1A1E A;  2EO3 A;  3VS4 A;  1R1S A;  2AUG A;  1AD5 A;  3QWY A;  2B3O A;  3C7I A;  3VRY A;  4EY0 A;  4K44 A;  4A4C A;  1X0N A;  1O4I A;  1ZFP E;  3VS3 A;  2OZO A;  3KFJ A;  5IBS A;  3VS1 A;  3GQI B;  3BUN B;  1CWD L;  2EYZ A;  1F1W A;  2DLY A;  4EIH A;  2GSB A;  3BKB A;  4GL9 E;  1SHA A;  1O4C A;  1KSW A;  1SPR A;  2CIA A;  1BFJ A;  2LQW A;  5DC0 B;  1SHB A;  3OB2 B;  3VS6 A;  5EG3 B;  1SPS A;  1O4F A;  1TCE A;  2MRK A;  3PSK A;  1HCT B;  3T04 A;  1O4D A;  1BF5 A;  2VIF A;  2RVF A;  3US4 A;  1HCS B;  4GPL B;  3S8L A;  2HUW A;  5EEQ A;  1BHF A;  1LUI A;  4D8K A;  4OHL A;  1Y57 A;  3CXL A;  1JU5 A;  4JE4 A;  1AOT F;  1BLJ A;  1UUR A;  1Z3K A;  2HMH A;  1A09 A;  2KK6 A;  5GJH A;  4OHH A;  2CR4 A;  2HDX A;  3IMJ A;  1FHS A;  2YU7 A;  2YSX A;  3UYO A;  2MRJ A;  2KNO A;  2HCK A;  5HKZ A;  5I6V A;  4NWF A;  2PNB A;  2ETZ A;  1M27 A;  3GXW A;  1AB2 A;  2MK2 A;  1A1A A;  2SHP A;  1SHD A;  3PS5 A;  3N8M A;  1RJA A;  1CSZ A;  4F5A A;  1O47 A;  2LNX A;  1MIL A;  5DF6 A;  2EYV A;  2EKX A;  1D1Z A;  3VGO A;  2CI8 A;  2IUG A;  5J3X A;  2LCT A;  3CWG A;  1FBV A;  1O48 A;  4DGP A;  1BKL A;  3ZNI A;  4A4B A;  3UF4 A;  3IMD A;  1JYU A;  5CDW A;  3PFV A;  1AYD A;  2LQN A;  1JYQ A;  3S8O A;  2H8H A;  3VRO A;  4ROJ A;  1O4L A;  1FYR A;  5AUL A;  1H9O A;  1A08 A;  1CSY A;  2Y1M A;  2IUH A;  3VS0 A;  1BKM A;  1XA6 A;  3VS7 A;  1G83 A;  4P9V A;  1R1Q A;  1M61 A;  1O4Q A;  4TZI A;  2FO0 A;  4OHE A;  2C9W A;  1KA7 A;  2XP1 A;  2DVJ A;  1FBZ A;  4WWQ A;  3IN8 A;  5BO4 A;  1GHU A;  3M7F A;  1O4O A;  2C0I A;  1D4W A;  1LUN A;  2EL8 A;  2ABL A;  3N7Y A;  4U17 A;  1RQQ C;  1QG1 E;  1R1P A;  1SKJ A;  3CBL A;  4DGX A;  1O4H A;  1LCJ A;  4E68 A;  1QCF A;  3EAZ A;  2DM0 A;  1F2F A;  4FL3 A;  2ECD A;  1I3Z A;  2RMX A;  5EEL A;  4X6S A;  1B47 A;  1FU5 A;  5AXI A;  1A1B A;  3PJP A;  3BUO B;  1JWO A;  1OO3 A;  2FCI A;  2H46 E;  1QAD A;  3HHM B;  5D0J A;  1BHH B;  4JEG A;  4E93 A;  3PQZ A;  2PLD A;  1O43 A;  1MW4 A;  2EO6 A;  4FL2 A;  1AYC A;  5KAZ A;  2SRC A;  2K79 B;  5IBM A;  2MC1 A;  1Y1U A;  1UUS A;  2RSY A;  2PLE A;  3NHN A;  2JYQ A;  4K11 A;  1AYB A;  2K7A B;  3S8N A;  3QWX X;  1RPY A;  2HDV A;  1LKL A;  1O41 A;  4OHD A;  5GJI A;  4LUE A;  1O49 A;  4FBN A;  1K9A A;  2BBU A;  3EAC A;  3PLF B;  1O4G A;  2EOB A;  1LUK A;  3VRR A;  5EHP A;  4GWF A;  1O4P A;  1AYA A;  1O44 A;  1O4N A;  2MQI A;  1KC2 A;  1JYR A;  1O4B A;  2CS0 A;  3S9K A;  4M4Z A;  2DX0 A;  3TKZ A;  2AOA A;  1YVH A;  1LUM A;  1OPK A;  3GXX A;  3BUX B;  2LNW A;  3WA4 A;  4NWG A;  3OP0 A;  1O4M A;  3OVE A;  4XZ1 A;  3VRN A;  1O42 A;  1IS0 A;  1IJR A;  2Y3A B;  2L3T A;  1OPL A;  2ROR A;  1GRI A;  1NRV A;  3MXY A;  2Y1N A;  3VS2 A;  2CI9 A;  1LKK A;  3TL0 A;  1X27 A;  1X6C A;  4LUD A;  3CD3 A;  1LCK A;  1CWE A;  2CBL A;  1YVL A;  2IZV A;  5DC9 A;  4XZ0 A;  1O4A A;  1BHH A;  4QSY A;  1A81 A;  1FU6 A;  1TZE E;  4K2R A;  4P9Z A;  3OV1 A;  3VRZ A;  4F59 A;  1OO4 A;  4K45 A;  4L1B B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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