2H5KA

Crystal structure of complex between the domain-swapped dimeric grb2 sh2 domain and shc-derived ligand, ac-nh-ptyr-val-asn-nh2
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
96
structure length
96
Chain Sequence
PHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and energetic aspects of Grb2-SH2 domain-swapping.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 21
structure length 96
sequence length 96
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2h5kA00
2H8HA 1KA6A 2ABLA 2AOAA 2GE9A 2IUHA 1RPYA 4E68A 2FCIA 2CBLA 1O42A 3PQZA 4K2RA 1NRVA 3VROA 3CXLA 2MQIA 1K9AA 2LCTA 1CSYA 3PJPA 2CIAA 2C0TA 1GRIA 1LUKA 1A1AA 3VS2A 4XZ0A 4GL9E 3VRQA 1RQQC 1O4CA 4EIHA 2IUGA 2RORA 2OZOA 1TZEE 3US4A 1GHUA 3S9KA 1R1QA 1M27A 4XZ1A 4JGHA 5DF6A 4U1PA 1SHDA 3TKZA 2SHPA 3BUNB 4ROJA 1B47A 4P9VA 4A4BA 1O4IA 2HDVA 3IN7A 2L3TA 3OB1B 1BHFA 3BUWB 3BKBA 1O4AA 1SHAA 2CR4A 1AYDA 4LUDA 5DC4A 2PLDA 4OHLA 1BF5A 4F5BA 1FHSA 1X27A 1O4PA 5AULA 2C9WA 1PICA 2CI9A 5KAZA 3WA4A 1AOTF 4FBNA 2BBUA 3KFJA 1UURA 3CWGA 4OHIA 1WQUA 4GPLB 3VRRA 5DC0B 2PNAA 2EYYA 2EO6A 4H1OA 3VS6A 3T04A 4E93A 5I6VA 4LUEA 3HCKA 3TL0A 3VS5A 2RVFA 2DCRA 4NWFA 2C0IA 1QCFA 5EEQA 1O4EA 2Y1NA 1LUIA 2KNOA 4K45A 1BMBA 2MC1A 1O4QA 2HUWA 2DM0A 1SPSA 2JYQA 3HHMB 2HDXA 2MRJA 5EELA 3OP0A 1JYUA 1JWOA 1Y57A 2IZVA 1O49A 3S8LA 1CSZA 2ETZA 2SRCA 2EYZA 1A1BA 3VS4A 1A81A 5HKWA 5CDWA 2EL8A 1LCJA 4F59A 1A07A 5IBMA 1FU5A 2GSBA 2H5KA 3OB2B 1D1ZA 3UF4A 3M7FA 1P13A 4WWQA 1LUNA 1OPKA 1FBVA 2H46E 1A1EA 2PLEA 1BLJA 1QADA 3ZNIA 3GQIB 1YVLA 1X0NA 1O46A 3VGOA 1O4BA 2LQWA 1IJRA 3N84A 2DLYA 1O4NA 3VRNA 4M4ZA 2K79B 1Z3KA 1O4RA 1BHHB 3BUOB 3CBLA 1BG1A 3PS5A 2CI8A 5IBSA 1AD5A 1QG1E 1O44A 5D0JA 4F5AA 1A08A 1SHBA 3IN8A 2K7AB 4NWGA 3K2MA 5EHRA 3GXWA 1CJ1A 1NZVA 1AYAA 1X6CA 1HCTB 1JYQA 2RMXA 1H9OA 2Y3AB 1O41A 4OHHA 2IUIA 1JYRA 3N8MA 2DLZA 1LKKA 3PSJA 4D8KA 1AYBA 5AXIA 5J3XA 1O4KA 2EU0A 2EO3A 3IMJA 3VRYA 3PLFB 3IMDA 3MAZA 2KK6A 3NHNA 1OO3A 3CD3A 1UUSA 2EKXA 1AB2A 1BKMA 1O4LA 2OQ1A 3MXYA 1AOUF 1O4OA 2C0OA 5EHPA 2DVJA 1XA6A 1KA7A 1R1PA 2B3OA 1KSWA 1IS0A 1A09A 2MK2A 1TCEA 1O4MA 1D4TA 1Y1UA 2HMHA 3VS1A 1AYCA 2LNWA 1R1SA 1O4DA 2MRKA 4P9ZA 1HCSB 2YSXA 2QMSA 2AOBA 4K44A 4OHDA 3C7IA 4K11A 5HKYA 1SPRA 2CRHA 1MILA 1O45A 1RJAA 2HCKA 3BUXB 1ZFPE 3BUMB 4X6SA 3QWYA 4U17A 4H34A 1O43A 5EG3B 1BFIA 2CS0A 2LQNA 2EYVA 1O4FA 1G83A 1O4HA 2XP1A 3VS7A 1BM2A 4DGXA 3VRZA 1FU6A 1LCKA 4QSYA 2EOBA 2L6KA 1OO4A 3VS3A 1BHHA 2RSYA 4GWFA 2L4KA 1YVHA 2ECDA 1O48A 1F1WA 5DC9A 5GJIA 1BFJA 3GXXA 3HIZB 1NZLA 3QWXX 4JE4A 3EACA 4JEGA 3VS0A 3VRPA 1CWDL 4L1BB 1FBZA 1D4WA 1OPLA 3MXCA 2LNXA 3OVEA 4DGPA 1LKLA 1A1CA 2VIFA 1BKLA 2DX0A 4FL3A 1F2FA 4A4CA 2Y1MA 5GJHA 1SKJA 1BLKA 2PNBA 4TZIA 5HKZA 1M61A 1LUMA 1MW4A 1FYRA 1JU5A 3PSKA 2AUGA 2FO0A 4OHEA 1I3ZA 3S8NA 1O4JA 4EY0A 1O4GA 5BO4A 1FMKA 3UYOA 2YU7A 3PFVA 2PTKA 1KC2A 3EAZA 1O47A 3OV1A 3S8OA 3N7YA 1CWEA 4FL2A
chains in the Genus database with same CATH superfamily
2H8HA 1KA6A 2ABLA 2AOAA 2GE9A 2IUHA 1RPYA 4E68A 2FCIA 2CBLA 1O42A 3PQZA 4K2RA 1NRVA 3VROA 3CXLA 2MQIA 1K9AA 2LCTA 1CSYA 3PJPA 2CIAA 2C0TA 1GRIA 1LUKA 1A1AA 3VS2A 4XZ0A 4GL9E 3VRQA 1RQQC 1O4CA 4EIHA 2IUGA 2RORA 2OZOA 1TZEE 3US4A 1GHUA 3S9KA 1R1QA 1M27A 4XZ1A 4JGHA 5DF6A 4U1PA 1SHDA 3TKZA 2SHPA 3BUNB 4ROJA 1B47A 4P9VA 4A4BA 1O4IA 2HDVA 3IN7A 2L3TA 3OB1B 1BHFA 3BUWB 3BKBA 1O4AA 1SHAA 2CR4A 1AYDA 4LUDA 5DC4A 2PLDA 4OHLA 1BF5A 4F5BA 1FHSA 1X27A 1O4PA 5AULA 2C9WA 1PICA 2CI9A 5KAZA 3WA4A 1AOTF 4FBNA 2BBUA 3KFJA 1UURA 3CWGA 4OHIA 1WQUA 4GPLB 3VRRA 5DC0B 2PNAA 2EYYA 2EO6A 4H1OA 3VS6A 3T04A 4E93A 5I6VA 4LUEA 3HCKA 3TL0A 3VS5A 2RVFA 2DCRA 4NWFA 2C0IA 1QCFA 5EEQA 1O4EA 2Y1NA 1LUIA 2KNOA 4K45A 1BMBA 2MC1A 1O4QA 2HUWA 2DM0A 1SPSA 2JYQA 3HHMB 2HDXA 2MRJA 5EELA 3OP0A 1JYUA 1JWOA 1Y57A 2IZVA 1O49A 3S8LA 1CSZA 2ETZA 2SRCA 2EYZA 1A1BA 3VS4A 1A81A 5HKWA 5CDWA 2EL8A 1LCJA 4F59A 1A07A 5IBMA 1FU5A 2GSBA 2H5KA 3OB2B 1D1ZA 3UF4A 3M7FA 1P13A 4WWQA 1LUNA 1OPKA 1FBVA 2H46E 1A1EA 2PLEA 1BLJA 1QADA 3ZNIA 3GQIB 1YVLA 1X0NA 1O46A 3VGOA 1O4BA 2LQWA 1IJRA 3N84A 2DLYA 1O4NA 3VRNA 4M4ZA 2K79B 1Z3KA 1O4RA 1BHHB 3BUOB 3CBLA 1BG1A 3PS5A 2CI8A 5IBSA 1AD5A 1QG1E 1O44A 5D0JA 4F5AA 1A08A 1SHBA 3IN8A 2K7AB 4NWGA 3K2MA 5EHRA 3GXWA 1CJ1A 1NZVA 1AYAA 1X6CA 1HCTB 1JYQA 2RMXA 1H9OA 2Y3AB 1O41A 4OHHA 2IUIA 1JYRA 3N8MA 2DLZA 1LKKA 3PSJA 4D8KA 1AYBA 5AXIA 5J3XA 1O4KA 2EU0A 2EO3A 3IMJA 3VRYA 3PLFB 3IMDA 3MAZA 2KK6A 3NHNA 1OO3A 3CD3A 1UUSA 2EKXA 1AB2A 1BKMA 1O4LA 2OQ1A 3MXYA 1AOUF 1O4OA 2C0OA 5EHPA 2DVJA 1XA6A 1KA7A 1R1PA 2B3OA 1KSWA 1IS0A 1A09A 2MK2A 1TCEA 1O4MA 1D4TA 1Y1UA 2HMHA 3VS1A 1AYCA 2LNWA 1R1SA 1O4DA 2MRKA 4P9ZA 1HCSB 3LYVA 2YSXA 2QMSA 2AOBA 4K44A 4OHDA 3C7IA 4K11A 5HKYA 1SPRA 2CRHA 1MILA 1O45A 1RJAA 2HCKA 3BUXB 1ZFPE 3BUMB 4X6SA 3QWYA 4U17A 4H34A 1O43A 5EG3B 1BFIA 2CS0A 2LQNA 2EYVA 1O4FA 1G83A 1O4HA 2XP1A 3VS7A 1BM2A 4DGXA 3VRZA 1FU6A 1LCKA 4QSYA 2EOBA 2L6KA 1OO4A 3VS3A 1BHHA 2RSYA 4GWFA 2L4KA 1YVHA 2ECDA 1O48A 1F1WA 5DC9A 2LRAA 5GJIA 1BFJA 3GXXA 3HIZB 1NZLA 3QWXX 4JE4A 3EACA 4JEGA 3VS0A 3VRPA 1CWDL 4L1BB 1FBZA 1D4WA 1OPLA 3MXCA 2LNXA 3OVEA 4DGPA 1LKLA 1A1CA 2VIFA 1BKLA 2DX0A 4FL3A 1F2FA 4A4CA 2Y1MA 5GJHA 1SKJA 1BLKA 2PNBA 4TZIA 5HKZA 2KGYA 1M61A 1LUMA 1MW4A 1FYRA 1JU5A 3PSKA 2AUGA 2FO0A 4OHEA 1I3ZA 3S8NA 1O4JA 4EY0A 1O4GA 5BO4A 3K2TA 1FMKA 3UYOA 2YU7A 3PFVA 2PTKA 1KC2A 3EAZA 1O47A 3OV1A 3S8OA 3N7YA 1CWEA 4FL2A
chains in the Genus database with same CATH topology
2H8HA 1KA6A 2ABLA 2AOAA 2GE9A 2IUHA 1RPYA 4E68A 2FCIA 2CBLA 1O42A 3PQZA 4K2RA 1NRVA 3VROA 3CXLA 2MQIA 1K9AA 2LCTA 1CSYA 3PJPA 2CIAA 2C0TA 1GRIA 1LUKA 1A1AA 3VS2A 4XZ0A 4GL9E 3VRQA 1RQQC 1O4CA 4EIHA 2IUGA 2RORA 2OZOA 1TZEE 3US4A 1GHUA 3S9KA 1R1QA 1M27A 4XZ1A 4JGHA 5DF6A 4U1PA 1SHDA 3TKZA 2SHPA 3BUNB 4ROJA 1B47A 4P9VA 4A4BA 1O4IA 2HDVA 3IN7A 2L3TA 3OB1B 1BHFA 3BUWB 3BKBA 1O4AA 1SHAA 2CR4A 1AYDA 4LUDA 5DC4A 2PLDA 4OHLA 1BF5A 4F5BA 1FHSA 1X27A 1O4PA 5AULA 2C9WA 1PICA 2CI9A 5KAZA 3WA4A 1AOTF 4FBNA 2BBUA 3KFJA 1UURA 3CWGA 4OHIA 1WQUA 4GPLB 3VRRA 5DC0B 2PNAA 2EYYA 2EO6A 4H1OA 3VS6A 3T04A 4E93A 5I6VA 4LUEA 3HCKA 3TL0A 3VS5A 2RVFA 2DCRA 4NWFA 2C0IA 1QCFA 5EEQA 1O4EA 2Y1NA 1LUIA 2KNOA 4K45A 1BMBA 2MC1A 1O4QA 2HUWA 2DM0A 1SPSA 2JYQA 3HHMB 2HDXA 2MRJA 5EELA 3OP0A 1JYUA 1JWOA 1Y57A 2IZVA 1O49A 3S8LA 1CSZA 2ETZA 2SRCA 2EYZA 1A1BA 3VS4A 1A81A 5HKWA 5CDWA 2EL8A 1LCJA 4F59A 1A07A 5IBMA 1FU5A 2GSBA 2H5KA 3OB2B 1D1ZA 3UF4A 3M7FA 1P13A 4WWQA 1LUNA 1OPKA 1FBVA 2H46E 1A1EA 2PLEA 1BLJA 1QADA 3ZNIA 3GQIB 1YVLA 1X0NA 1O46A 3VGOA 1O4BA 2LQWA 1IJRA 3N84A 2DLYA 1O4NA 3VRNA 4M4ZA 2K79B 1Z3KA 1O4RA 1BHHB 3BUOB 3CBLA 1BG1A 3PS5A 2CI8A 5IBSA 1AD5A 1QG1E 1O44A 5D0JA 4F5AA 1A08A 1SHBA 3IN8A 2K7AB 4NWGA 3K2MA 5EHRA 3GXWA 1CJ1A 1NZVA 1AYAA 1X6CA 1HCTB 1JYQA 2RMXA 1H9OA 2Y3AB 1O41A 4OHHA 2IUIA 1JYRA 3N8MA 2DLZA 1LKKA 3PSJA 4D8KA 1AYBA 5AXIA 5J3XA 1O4KA 2EU0A 2EO3A 3IMJA 3VRYA 3PLFB 3IMDA 3MAZA 2KK6A 3NHNA 1OO3A 3CD3A 1UUSA 2EKXA 1AB2A 1BKMA 1O4LA 2OQ1A 3MXYA 1AOUF 1O4OA 2C0OA 5EHPA 2DVJA 1XA6A 1KA7A 1R1PA 2B3OA 1KSWA 1IS0A 1A09A 2MK2A 1TCEA 1O4MA 1D4TA 1Y1UA 2HMHA 3VS1A 1AYCA 2LNWA 1R1SA 1O4DA 2MRKA 4P9ZA 1HCSB 2YSXA 2QMSA 2AOBA 4K44A 4OHDA 3C7IA 4K11A 5HKYA 1SPRA 2CRHA 1MILA 1O45A 1RJAA 2HCKA 3BUXB 1ZFPE 3BUMB 4X6SA 3QWYA 4U17A 4H34A 1O43A 5EG3B 1BFIA 2CS0A 2LQNA 2EYVA 1O4FA 1G83A 1O4HA 2XP1A 3VS7A 1BM2A 4DGXA 3VRZA 1FU6A 1LCKA 4QSYA 2EOBA 2L6KA 1OO4A 3VS3A 1BHHA 2RSYA 4GWFA 2L4KA 1YVHA 2ECDA 1O48A 1F1WA 5DC9A 5GJIA 1BFJA 3GXXA 3HIZB 1NZLA 3QWXX 4JE4A 3EACA 4JEGA 3VS0A 3VRPA 1CWDL 4L1BB 1FBZA 1D4WA 1OPLA 3MXCA 2LNXA 3OVEA 4DGPA 1LKLA 1A1CA 2VIFA 1BKLA 2DX0A 4FL3A 1F2FA 4A4CA 2Y1MA 5GJHA 1SKJA 1BLKA 2PNBA 4TZIA 5HKZA 1M61A 1LUMA 1MW4A 1FYRA 1JU5A 3PSKA 2AUGA 2FO0A 4OHEA 1I3ZA 3S8NA 1O4JA 4EY0A 1O4GA 5BO4A 1FMKA 3UYOA 2YU7A 3PFVA 2PTKA 1KC2A 3EAZA 1O47A 3OV1A 3S8OA 3N7YA 1CWEA 4FL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H8H A;  1KA6 A;  2ABL A;  2AOA A;  2GE9 A;  2IUH A;  1RPY A;  4E68 A;  2FCI A;  2CBL A;  1O42 A;  3PQZ A;  4K2R A;  1NRV A;  3VRO A;  3CXL A;  2MQI A;  1K9A A;  2LCT A;  1CSY A;  3PJP A;  2CIA A;  2C0T A;  1GRI A;  1LUK A;  1A1A A;  3VS2 A;  4XZ0 A;  4GL9 E;  3VRQ A;  1RQQ C;  1O4C A;  4EIH A;  2IUG A;  2ROR A;  2OZO A;  1TZE E;  3US4 A;  1GHU A;  3S9K A;  1R1Q A;  1M27 A;  4XZ1 A;  4JGH A;  5DF6 A;  4U1P A;  1SHD A;  3TKZ A;  2SHP A;  3BUN B;  4ROJ A;  1B47 A;  4P9V A;  4A4B A;  1O4I A;  2HDV A;  3IN7 A;  2L3T A;  3OB1 B;  1BHF A;  3BUW B;  3BKB A;  1O4A A;  1SHA A;  2CR4 A;  1AYD A;  4LUD A;  5DC4 A;  2PLD A;  4OHL A;  1BF5 A;  4F5B A;  1FHS A;  1X27 A;  1O4P A;  5AUL A;  2C9W A;  1PIC A;  2CI9 A;  5KAZ A;  3WA4 A;  1AOT F;  4FBN A;  2BBU A;  3KFJ A;  1UUR A;  3CWG A;  4OHI A;  1WQU A;  4GPL B;  3VRR A;  5DC0 B;  2PNA A;  2EYY A;  2EO6 A;  4H1O A;  3VS6 A;  3T04 A;  4E93 A;  5I6V A;  4LUE A;  3HCK A;  3TL0 A;  3VS5 A;  2RVF A;  2DCR A;  4NWF A;  2C0I A;  1QCF A;  5EEQ A;  1O4E A;  2Y1N A;  1LUI A;  2KNO A;  4K45 A;  1BMB A;  2MC1 A;  1O4Q A;  2HUW A;  2DM0 A;  1SPS A;  2JYQ A;  3HHM B;  2HDX A;  2MRJ A;  5EEL A;  3OP0 A;  1JYU A;  1JWO A;  1Y57 A;  2IZV A;  1O49 A;  3S8L A;  1CSZ A;  2ETZ A;  2SRC A;  2EYZ A;  1A1B A;  3VS4 A;  1A81 A;  5HKW A;  5CDW A;  2EL8 A;  1LCJ A;  4F59 A;  1A07 A;  5IBM A;  1FU5 A;  2GSB A;  2H5K A;  3OB2 B;  1D1Z A;  3UF4 A;  3M7F A;  1P13 A;  4WWQ A;  1LUN A;  1OPK A;  1FBV A;  2H46 E;  1A1E A;  2PLE A;  1BLJ A;  1QAD A;  3ZNI A;  3GQI B;  1YVL A;  1X0N A;  1O46 A;  3VGO A;  1O4B A;  2LQW A;  1IJR A;  3N84 A;  2DLY A;  1O4N A;  3VRN A;  4M4Z A;  2K79 B;  1Z3K A;  1O4R A;  1BHH B;  3BUO B;  3CBL A;  1BG1 A;  3PS5 A;  2CI8 A;  5IBS A;  1AD5 A;  1QG1 E;  1O44 A;  5D0J A;  4F5A A;  1A08 A;  1SHB A;  3IN8 A;  2K7A B;  4NWG A;  3K2M A;  5EHR A;  3GXW A;  1CJ1 A;  1NZV A;  1AYA A;  1X6C A;  1HCT B;  1JYQ A;  2RMX A;  1H9O A;  2Y3A B;  1O41 A;  4OHH A;  2IUI A;  1JYR A;  3N8M A;  2DLZ A;  1LKK A;  3PSJ A;  4D8K A;  1AYB A;  5AXI A;  5J3X A;  1O4K A;  2EU0 A;  2EO3 A;  3IMJ A;  3VRY A;  3PLF B;  3IMD A;  3MAZ A;  2KK6 A;  3NHN A;  1OO3 A;  3CD3 A;  1UUS A;  2EKX A;  1AB2 A;  1BKM A;  1O4L A;  2OQ1 A;  3MXY A;  1AOU F;  1O4O A;  2C0O A;  5EHP A;  2DVJ A;  1XA6 A;  1KA7 A;  1R1P A;  2B3O A;  1KSW A;  1IS0 A;  1A09 A;  2MK2 A;  1TCE A;  1O4M A;  1D4T A;  1Y1U A;  2HMH A;  3VS1 A;  1AYC A;  2LNW A;  1R1S A;  1O4D A;  2MRK A;  4P9Z A;  1HCS B;  2YSX A;  2QMS A;  2AOB A;  4K44 A;  4OHD A;  3C7I A;  4K11 A;  5HKY A;  1SPR A;  2CRH A;  1MIL A;  1O45 A;  1RJA A;  2HCK A;  3BUX B;  1ZFP E;  3BUM B;  4X6S A;  3QWY A;  4U17 A;  4H34 A;  1O43 A;  5EG3 B;  1BFI A;  2CS0 A;  2LQN A;  2EYV A;  1O4F A;  1G83 A;  1O4H A;  2XP1 A;  3VS7 A;  1BM2 A;  4DGX A;  3VRZ A;  1FU6 A;  1LCK A;  4QSY A;  2EOB A;  2L6K A;  1OO4 A;  3VS3 A;  1BHH A;  2RSY A;  4GWF A;  2L4K A;  1YVH A;  2ECD A;  1O48 A;  1F1W A;  5DC9 A;  5GJI A;  1BFJ A;  3GXX A;  3HIZ B;  1NZL A;  3QWX X;  4JE4 A;  3EAC A;  4JEG A;  3VS0 A;  3VRP A;  1CWD L;  4L1B B;  1FBZ A;  1D4W A;  1OPL A;  3MXC A;  2LNX A;  3OVE A;  4DGP A;  1LKL A;  1A1C A;  2VIF A;  1BKL A;  2DX0 A;  4FL3 A;  1F2F A;  4A4C A;  2Y1M A;  5GJH A;  1SKJ A;  1BLK A;  2PNB A;  4TZI A;  5HKZ A;  1M61 A;  1LUM A;  1MW4 A;  1FYR A;  1JU5 A;  3PSK A;  2AUG A;  2FO0 A;  4OHE A;  1I3Z A;  3S8N A;  1O4J A;  4EY0 A;  1O4G A;  5BO4 A;  1FMK A;  3UYO A;  2YU7 A;  3PFV A;  2PTK A;  1KC2 A;  3EAZ A;  1O47 A;  3OV1 A;  3S8O A;  3N7Y A;  1CWE A;  4FL2 A; 
#chains in the Genus database with same CATH topology
 2H8H A;  1KA6 A;  2ABL A;  2AOA A;  2GE9 A;  2IUH A;  1RPY A;  4E68 A;  2FCI A;  2CBL A;  1O42 A;  3PQZ A;  4K2R A;  1NRV A;  3VRO A;  3CXL A;  2MQI A;  1K9A A;  2LCT A;  1CSY A;  3PJP A;  2CIA A;  2C0T A;  1GRI A;  1LUK A;  1A1A A;  3VS2 A;  4XZ0 A;  4GL9 E;  3VRQ A;  1RQQ C;  1O4C A;  4EIH A;  2IUG A;  2ROR A;  2OZO A;  1TZE E;  3US4 A;  1GHU A;  3S9K A;  1R1Q A;  1M27 A;  4XZ1 A;  4JGH A;  5DF6 A;  4U1P A;  1SHD A;  3TKZ A;  2SHP A;  3BUN B;  4ROJ A;  1B47 A;  4P9V A;  4A4B A;  1O4I A;  2HDV A;  3IN7 A;  2L3T A;  3OB1 B;  1BHF A;  3BUW B;  3BKB A;  1O4A A;  1SHA A;  2CR4 A;  1AYD A;  4LUD A;  5DC4 A;  2PLD A;  4OHL A;  1BF5 A;  4F5B A;  1FHS A;  1X27 A;  1O4P A;  5AUL A;  2C9W A;  1PIC A;  2CI9 A;  5KAZ A;  3WA4 A;  1AOT F;  4FBN A;  2BBU A;  3KFJ A;  1UUR A;  3CWG A;  4OHI A;  1WQU A;  4GPL B;  3VRR A;  5DC0 B;  2PNA A;  2EYY A;  2EO6 A;  4H1O A;  3VS6 A;  3T04 A;  4E93 A;  5I6V A;  4LUE A;  3HCK A;  3TL0 A;  3VS5 A;  2RVF A;  2DCR A;  4NWF A;  2C0I A;  1QCF A;  5EEQ A;  1O4E A;  2Y1N A;  1LUI A;  2KNO A;  4K45 A;  1BMB A;  2MC1 A;  1O4Q A;  2HUW A;  2DM0 A;  1SPS A;  2JYQ A;  3HHM B;  2HDX A;  2MRJ A;  5EEL A;  3OP0 A;  1JYU A;  1JWO A;  1Y57 A;  2IZV A;  1O49 A;  3S8L A;  1CSZ A;  2ETZ A;  2SRC A;  2EYZ A;  1A1B A;  3VS4 A;  1A81 A;  5HKW A;  5CDW A;  2EL8 A;  1LCJ A;  4F59 A;  1A07 A;  5IBM A;  1FU5 A;  2GSB A;  2H5K A;  3OB2 B;  1D1Z A;  3UF4 A;  3M7F A;  1P13 A;  4WWQ A;  1LUN A;  1OPK A;  1FBV A;  2H46 E;  1A1E A;  2PLE A;  1BLJ A;  1QAD A;  3ZNI A;  3GQI B;  1YVL A;  1X0N A;  1O46 A;  3VGO A;  1O4B A;  2LQW A;  1IJR A;  3N84 A;  2DLY A;  1O4N A;  3VRN A;  4M4Z A;  2K79 B;  1Z3K A;  1O4R A;  1BHH B;  3BUO B;  3CBL A;  1BG1 A;  3PS5 A;  2CI8 A;  5IBS A;  1AD5 A;  1QG1 E;  1O44 A;  5D0J A;  4F5A A;  1A08 A;  1SHB A;  3IN8 A;  2K7A B;  4NWG A;  3K2M A;  5EHR A;  3GXW A;  1CJ1 A;  1NZV A;  1AYA A;  1X6C A;  1HCT B;  1JYQ A;  2RMX A;  1H9O A;  2Y3A B;  1O41 A;  4OHH A;  2IUI A;  1JYR A;  3N8M A;  2DLZ A;  1LKK A;  3PSJ A;  4D8K A;  1AYB A;  5AXI A;  5J3X A;  1O4K A;  2EU0 A;  2EO3 A;  3IMJ A;  3VRY A;  3PLF B;  3IMD A;  3MAZ A;  2KK6 A;  3NHN A;  1OO3 A;  3CD3 A;  1UUS A;  2EKX A;  1AB2 A;  1BKM A;  1O4L A;  2OQ1 A;  3MXY A;  1AOU F;  1O4O A;  2C0O A;  5EHP A;  2DVJ A;  1XA6 A;  1KA7 A;  1R1P A;  2B3O A;  1KSW A;  1IS0 A;  1A09 A;  2MK2 A;  1TCE A;  1O4M A;  1D4T A;  1Y1U A;  2HMH A;  3VS1 A;  1AYC A;  2LNW A;  1R1S A;  1O4D A;  2MRK A;  4P9Z A;  1HCS B;  3LYV A;  2YSX A;  2QMS A;  2AOB A;  4K44 A;  4OHD A;  3C7I A;  4K11 A;  5HKY A;  1SPR A;  2CRH A;  1MIL A;  1O45 A;  1RJA A;  2HCK A;  3BUX B;  1ZFP E;  3BUM B;  4X6S A;  3QWY A;  4U17 A;  4H34 A;  1O43 A;  5EG3 B;  1BFI A;  2CS0 A;  2LQN A;  2EYV A;  1O4F A;  1G83 A;  1O4H A;  2XP1 A;  3VS7 A;  1BM2 A;  4DGX A;  3VRZ A;  1FU6 A;  1LCK A;  4QSY A;  2EOB A;  2L6K A;  1OO4 A;  3VS3 A;  1BHH A;  2RSY A;  4GWF A;  2L4K A;  1YVH A;  2ECD A;  1O48 A;  1F1W A;  5DC9 A;  2LRA A;  5GJI A;  1BFJ A;  3GXX A;  3HIZ B;  1NZL A;  3QWX X;  4JE4 A;  3EAC A;  4JEG A;  3VS0 A;  3VRP A;  1CWD L;  4L1B B;  1FBZ A;  1D4W A;  1OPL A;  3MXC A;  2LNX A;  3OVE A;  4DGP A;  1LKL A;  1A1C A;  2VIF A;  1BKL A;  2DX0 A;  4FL3 A;  1F2F A;  4A4C A;  2Y1M A;  5GJH A;  1SKJ A;  1BLK A;  2PNB A;  4TZI A;  5HKZ A;  2KGY A;  1M61 A;  1LUM A;  1MW4 A;  1FYR A;  1JU5 A;  3PSK A;  2AUG A;  2FO0 A;  4OHE A;  1I3Z A;  3S8N A;  1O4J A;  4EY0 A;  1O4G A;  5BO4 A;  3K2T A;  1FMK A;  3UYO A;  2YU7 A;  3PFV A;  2PTK A;  1KC2 A;  3EAZ A;  1O47 A;  3OV1 A;  3S8O A;  3N7Y A;  1CWE A;  4FL2 A; 
#chains in the Genus database with same CATH homology
 2H8H A;  1KA6 A;  2ABL A;  2AOA A;  2GE9 A;  2IUH A;  1RPY A;  4E68 A;  2FCI A;  2CBL A;  1O42 A;  3PQZ A;  4K2R A;  1NRV A;  3VRO A;  3CXL A;  2MQI A;  1K9A A;  2LCT A;  1CSY A;  3PJP A;  2CIA A;  2C0T A;  1GRI A;  1LUK A;  1A1A A;  3VS2 A;  4XZ0 A;  4GL9 E;  3VRQ A;  1RQQ C;  1O4C A;  4EIH A;  2IUG A;  2ROR A;  2OZO A;  1TZE E;  3US4 A;  1GHU A;  3S9K A;  1R1Q A;  1M27 A;  4XZ1 A;  4JGH A;  5DF6 A;  4U1P A;  1SHD A;  3TKZ A;  2SHP A;  3BUN B;  4ROJ A;  1B47 A;  4P9V A;  4A4B A;  1O4I A;  2HDV A;  3IN7 A;  2L3T A;  3OB1 B;  1BHF A;  3BUW B;  3BKB A;  1O4A A;  1SHA A;  2CR4 A;  1AYD A;  4LUD A;  5DC4 A;  2PLD A;  4OHL A;  1BF5 A;  4F5B A;  1FHS A;  1X27 A;  1O4P A;  5AUL A;  2C9W A;  1PIC A;  2CI9 A;  5KAZ A;  3WA4 A;  1AOT F;  4FBN A;  2BBU A;  3KFJ A;  1UUR A;  3CWG A;  4OHI A;  1WQU A;  4GPL B;  3VRR A;  5DC0 B;  2PNA A;  2EYY A;  2EO6 A;  4H1O A;  3VS6 A;  3T04 A;  4E93 A;  5I6V A;  4LUE A;  3HCK A;  3TL0 A;  3VS5 A;  2RVF A;  2DCR A;  4NWF A;  2C0I A;  1QCF A;  5EEQ A;  1O4E A;  2Y1N A;  1LUI A;  2KNO A;  4K45 A;  1BMB A;  2MC1 A;  1O4Q A;  2HUW A;  2DM0 A;  1SPS A;  2JYQ A;  3HHM B;  2HDX A;  2MRJ A;  5EEL A;  3OP0 A;  1JYU A;  1JWO A;  1Y57 A;  2IZV A;  1O49 A;  3S8L A;  1CSZ A;  2ETZ A;  2SRC A;  2EYZ A;  1A1B A;  3VS4 A;  1A81 A;  5HKW A;  5CDW A;  2EL8 A;  1LCJ A;  4F59 A;  1A07 A;  5IBM A;  1FU5 A;  2GSB A;  2H5K A;  3OB2 B;  1D1Z A;  3UF4 A;  3M7F A;  1P13 A;  4WWQ A;  1LUN A;  1OPK A;  1FBV A;  2H46 E;  1A1E A;  2PLE A;  1BLJ A;  1QAD A;  3ZNI A;  3GQI B;  1YVL A;  1X0N A;  1O46 A;  3VGO A;  1O4B A;  2LQW A;  1IJR A;  3N84 A;  2DLY A;  1O4N A;  3VRN A;  4M4Z A;  2K79 B;  1Z3K A;  1O4R A;  1BHH B;  3BUO B;  3CBL A;  1BG1 A;  3PS5 A;  2CI8 A;  5IBS A;  1AD5 A;  1QG1 E;  1O44 A;  5D0J A;  4F5A A;  1A08 A;  1SHB A;  3IN8 A;  2K7A B;  4NWG A;  3K2M A;  5EHR A;  3GXW A;  1CJ1 A;  1NZV A;  1AYA A;  1X6C A;  1HCT B;  1JYQ A;  2RMX A;  1H9O A;  2Y3A B;  1O41 A;  4OHH A;  2IUI A;  1JYR A;  3N8M A;  2DLZ A;  1LKK A;  3PSJ A;  4D8K A;  1AYB A;  5AXI A;  5J3X A;  1O4K A;  2EU0 A;  2EO3 A;  3IMJ A;  3VRY A;  3PLF B;  3IMD A;  3MAZ A;  2KK6 A;  3NHN A;  1OO3 A;  3CD3 A;  1UUS A;  2EKX A;  1AB2 A;  1BKM A;  1O4L A;  2OQ1 A;  3MXY A;  1AOU F;  1O4O A;  2C0O A;  5EHP A;  2DVJ A;  1XA6 A;  1KA7 A;  1R1P A;  2B3O A;  1KSW A;  1IS0 A;  1A09 A;  2MK2 A;  1TCE A;  1O4M A;  1D4T A;  1Y1U A;  2HMH A;  3VS1 A;  1AYC A;  2LNW A;  1R1S A;  1O4D A;  2MRK A;  4P9Z A;  1HCS B;  2YSX A;  2QMS A;  2AOB A;  4K44 A;  4OHD A;  3C7I A;  4K11 A;  5HKY A;  1SPR A;  2CRH A;  1MIL A;  1O45 A;  1RJA A;  2HCK A;  3BUX B;  1ZFP E;  3BUM B;  4X6S A;  3QWY A;  4U17 A;  4H34 A;  1O43 A;  5EG3 B;  1BFI A;  2CS0 A;  2LQN A;  2EYV A;  1O4F A;  1G83 A;  1O4H A;  2XP1 A;  3VS7 A;  1BM2 A;  4DGX A;  3VRZ A;  1FU6 A;  1LCK A;  4QSY A;  2EOB A;  2L6K A;  1OO4 A;  3VS3 A;  1BHH A;  2RSY A;  4GWF A;  2L4K A;  1YVH A;  2ECD A;  1O48 A;  1F1W A;  5DC9 A;  5GJI A;  1BFJ A;  3GXX A;  3HIZ B;  1NZL A;  3QWX X;  4JE4 A;  3EAC A;  4JEG A;  3VS0 A;  3VRP A;  1CWD L;  4L1B B;  1FBZ A;  1D4W A;  1OPL A;  3MXC A;  2LNX A;  3OVE A;  4DGP A;  1LKL A;  1A1C A;  2VIF A;  1BKL A;  2DX0 A;  4FL3 A;  1F2F A;  4A4C A;  2Y1M A;  5GJH A;  1SKJ A;  1BLK A;  2PNB A;  4TZI A;  5HKZ A;  1M61 A;  1LUM A;  1MW4 A;  1FYR A;  1JU5 A;  3PSK A;  2AUG A;  2FO0 A;  4OHE A;  1I3Z A;  3S8N A;  1O4J A;  4EY0 A;  1O4G A;  5BO4 A;  1FMK A;  3UYO A;  2YU7 A;  3PFV A;  2PTK A;  1KC2 A;  3EAZ A;  1O47 A;  3OV1 A;  3S8O A;  3N7Y A;  1CWE A;  4FL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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