2MRJA

Structure of fyn protein sh2 bound
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
100
structure length
100
Chain Sequence
WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity.
pubmed doi rcsb
molecule keywords Tyrosine-protein kinase Fyn
molecule tags Transferase
source organism Homo sapiens
total genus 14
structure length 100
sequence length 100
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2014-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2mrjA00
1OPLA 2MRJA 1BLKA 3PSJA 1M61A 2HDVA 2HCKA 1O4BA 1SHDA 3OB1B 2DX0A 5GJIA 1BFJA 1CWDL 1MW4A 2LQNA 2DCRA 2K7AB 1O43A 1O4MA 3MXYA 1O4DA 3HHMB 2DLYA 2ETZA 4M4ZA 3GXWA 4QSYA 2K79B 2EYZA 4K44A 3VROA 3BUXB 1AYBA 2CI9A 4GWFA 1A1BA 3S8NA 1SPRA 1QCFA 1BHHA 1NRVA 4F5AA 2OZOA 2MC1A 1BMBA 3VS3A 1AYCA 2MRKA 1BLJA 5HKYA 1H9OA 1KA6A 2CBLA 1CWEA 3BKBA 1O4GA 3ZNIA 2B3OA 3K2MA 1FU6A 1R1QA 2RORA 4NWFA 1B47A 2YSXA 1O4HA 3OP0A 1OPKA 2YU7A 1BHHB 1KSWA 3GQIB 5BO4A 4OHIA 3T04A 4LUDA 2EL8A 2L6KA 3S9KA 1JWOA 3N84A 1BKLA 1WQUA 4E68A 4P9ZA 2LNWA 3BUOB 1NZLA 5DC0B 3MXCA 2LCTA 3IN7A 1O47A 3VGOA 1LCKA 1YVLA 2HMHA 4DGXA 3VS7A 3PLFB 1FHSA 1A81A 3US4A 2Y1MA 1JU5A 2KK6A 1ZFPE 4OHEA 3WA4A 3HIZB 3VS1A 3CWGA 1KA7A 1AOTF 5I6VA 1QG1E 1O4RA 1R1SA 2H46E 2PNBA 4K45A 2CI8A 4FL3A 1IS0A 1LUKA 4U17A 5IBMA 1JYQA 1G83A 2LQWA 1A09A 4F5BA 1YVHA 1O4CA 2Y1NA 2RSYA 3N8MA 2L4KA 1FU5A 1O4KA 4LUEA 2SHPA 3TKZA 1D4WA 3UF4A 4EIHA 3BUMB 2LNXA 1X0NA 1AD5A 4D8KA 2C0IA 3N7YA 3VS5A 1O45A 4OHDA 2CIAA 1O42A 5HKWA 3VS6A 4K11A 1A1CA 1Z3KA 5D0JA 4H1OA 3KFJA 3VS4A 1O48A 1X27A 3CBLA 3VRNA 4A4CA 3S8LA 3OV1A 4U1PA 5IBSA 4NWGA 1RJAA 3MAZA 2PNAA 2MK2A 1LUNA 1JYRA 1AYAA 3VRPA 1UURA 1RQQC 2GSBA 1UUSA 1K9AA 4K2RA 2ECDA 3NHNA 2SRCA 4XZ1A 1TCEA 1A1EA 3VRYA 3OVEA 1P13A 2C0OA 1FMKA 2EKXA 1X6CA 2L3TA 2EOBA 5J3XA 2AOBA 2EYYA 3PFVA 4FL2A 2PLDA 1O4JA 2H5KA 1BM2A 1HCSB 3VRQA 5DF6A 1RPYA 4EY0A 1KC2A 2CR4A 5EHRA 5AULA 1A07A 2HUWA 3VRZA 2C0TA 1GRIA 2MQIA 3BUNB 4FBNA 1CSZA 1Y57A 1AOUF 1SKJA 1O41A 1TZEE 3GXXA 2AUGA 2HDXA 4TZIA 1FYRA 2DLZA 4L1BB 4A4BA 2CRHA 1QADA 1IJRA 3C7IA 3HCKA 2C9WA 4GPLB 5DC9A 5GJHA 1CSYA 3BUWB 3EAZA 2FO0A 1I3ZA 2H8HA 3PSKA 4GL9E 2EYVA 2AOAA 2EO6A 3UYOA 3OB2B 5EEQA 2IUIA 1O4FA 1JYUA 3PJPA 1O4IA 4F59A 3S8OA 1GHUA 2VIFA 3IMJA 3QWYA 1HCTB 1OO3A 1LCJA 3VRRA 1OO4A 3M7FA 2CS0A 1Y1UA 1O4LA 1BHFA 2GE9A 1LUMA 4JGHA 1FBVA 1LKKA 3QWXX 5EG3B 1SPSA 5HKZA 2IUHA 2XP1A 2JYQA 2IUGA 1PICA 1A08A 1D4TA 4E93A 3CXLA 3CD3A 4OHHA 5EHPA 1SHBA 4P9VA 1BG1A 5DC4A 4H34A 1O4QA 1BFIA 2IZVA 2ABLA 2KNOA 4WWQA 3TL0A 3PS5A 1F1WA 2EO3A 1CJ1A 2RMXA 3PQZA 2EU0A 1D1ZA 1AYDA 1SHAA 4ROJA 2PTKA 1O44A 1O4AA 1XA6A 2PLEA 3EACA 4JEGA 1M27A 1O49A 3VS0A 4OHLA 2RVFA 5CDWA 2FCIA 1LKLA 1O4EA 1O4PA 2Y3AB 1O46A 5AXIA 1O4OA 1LUIA 2QMSA 5EELA 1BF5A 1BKMA 3IMDA 4X6SA 1MILA 2DM0A 4DGPA 1NZVA 1O4NA 1F2FA 1AB2A 2DVJA 2OQ1A 5KAZA 1A1AA 1R1PA 1FBZA 4XZ0A 4JE4A 2BBUA 3VS2A 3IN8A
chains in the Genus database with same CATH superfamily
1OPLA 2MRJA 1BLKA 3PSJA 1M61A 2HDVA 2HCKA 1O4BA 1SHDA 3OB1B 2DX0A 5GJIA 1BFJA 1CWDL 1MW4A 2LQNA 2DCRA 2K7AB 1O43A 1O4MA 3MXYA 1O4DA 3HHMB 2DLYA 2ETZA 4M4ZA 3GXWA 4QSYA 2K79B 2EYZA 4K44A 3VROA 3BUXB 1AYBA 2CI9A 4GWFA 1A1BA 3S8NA 1SPRA 1QCFA 1BHHA 1NRVA 4F5AA 2OZOA 2MC1A 1BMBA 3VS3A 1AYCA 2MRKA 1BLJA 5HKYA 1H9OA 1KA6A 2CBLA 1CWEA 3BKBA 1O4GA 3ZNIA 2B3OA 3K2MA 1FU6A 1R1QA 2RORA 4NWFA 1B47A 2YSXA 1O4HA 3OP0A 1OPKA 2YU7A 1BHHB 1KSWA 3GQIB 5BO4A 4OHIA 3T04A 4LUDA 2EL8A 2L6KA 3S9KA 1JWOA 3N84A 1BKLA 1WQUA 4E68A 4P9ZA 2LNWA 3BUOB 1NZLA 5DC0B 3MXCA 2LCTA 3K2TA 3IN7A 1O47A 3VGOA 1LCKA 1YVLA 2HMHA 4DGXA 3VS7A 3PLFB 1FHSA 1A81A 3US4A 2Y1MA 1JU5A 2KK6A 1ZFPE 4OHEA 3WA4A 3HIZB 3VS1A 3CWGA 1KA7A 1AOTF 5I6VA 1QG1E 1O4RA 1R1SA 2H46E 2PNBA 4K45A 2CI8A 4FL3A 1IS0A 1LUKA 4U17A 5IBMA 1JYQA 1G83A 2LQWA 1A09A 4F5BA 1YVHA 1O4CA 2Y1NA 2RSYA 3N8MA 2L4KA 1FU5A 1O4KA 4LUEA 2SHPA 3TKZA 1D4WA 3UF4A 4EIHA 3BUMB 2LNXA 1X0NA 1AD5A 4D8KA 2C0IA 3N7YA 3VS5A 1O45A 4OHDA 2CIAA 1O42A 5HKWA 3VS6A 4K11A 1A1CA 1Z3KA 5D0JA 4H1OA 3KFJA 3VS4A 1O48A 1X27A 3CBLA 3VRNA 4A4CA 3S8LA 3OV1A 4U1PA 5IBSA 4NWGA 1RJAA 3MAZA 2PNAA 2MK2A 1LUNA 1JYRA 1AYAA 3VRPA 1UURA 1RQQC 2GSBA 1UUSA 1K9AA 4K2RA 2ECDA 3NHNA 2SRCA 4XZ1A 1TCEA 1A1EA 3VRYA 3OVEA 3LYVA 1P13A 2C0OA 1FMKA 2EKXA 1X6CA 2L3TA 2EOBA 5J3XA 2AOBA 2EYYA 3PFVA 4FL2A 2PLDA 1O4JA 2H5KA 1BM2A 1HCSB 3VRQA 5DF6A 1RPYA 4EY0A 1KC2A 2CR4A 5EHRA 5AULA 1A07A 2HUWA 3VRZA 2C0TA 1GRIA 2MQIA 3BUNB 4FBNA 1CSZA 1Y57A 1AOUF 1SKJA 1O41A 1TZEE 3GXXA 2AUGA 2HDXA 2LRAA 4TZIA 1FYRA 2DLZA 4L1BB 4A4BA 2CRHA 1QADA 1IJRA 3C7IA 3HCKA 2C9WA 4GPLB 5DC9A 5GJHA 1CSYA 3BUWB 3EAZA 2FO0A 1I3ZA 2H8HA 3PSKA 4GL9E 2EYVA 2AOAA 2EO6A 3UYOA 3OB2B 5EEQA 2IUIA 1O4FA 1JYUA 3PJPA 1O4IA 4F59A 3S8OA 1GHUA 2VIFA 3IMJA 3QWYA 1HCTB 1OO3A 1LCJA 3VRRA 1OO4A 3M7FA 2CS0A 1Y1UA 1O4LA 1BHFA 2GE9A 1LUMA 4JGHA 1FBVA 1LKKA 3QWXX 5EG3B 1SPSA 5HKZA 2IUHA 2XP1A 2JYQA 2IUGA 1PICA 1A08A 1D4TA 4E93A 3CXLA 3CD3A 4OHHA 5EHPA 1SHBA 4P9VA 1BG1A 5DC4A 4H34A 1O4QA 1BFIA 2IZVA 2ABLA 2KNOA 4WWQA 3TL0A 3PS5A 1F1WA 2EO3A 1CJ1A 2RMXA 3PQZA 2EU0A 1D1ZA 1AYDA 1SHAA 2KGYA 4ROJA 2PTKA 1O44A 1O4AA 1XA6A 2PLEA 3EACA 4JEGA 1M27A 1O49A 3VS0A 4OHLA 2RVFA 5CDWA 2FCIA 1LKLA 1O4EA 1O4PA 2Y3AB 1O46A 5AXIA 1O4OA 1LUIA 2QMSA 5EELA 1BF5A 1BKMA 3IMDA 4X6SA 1MILA 2DM0A 4DGPA 1NZVA 1O4NA 1F2FA 1AB2A 2DVJA 2OQ1A 5KAZA 1A1AA 1R1PA 1FBZA 4XZ0A 4JE4A 2BBUA 3VS2A 3IN8A
chains in the Genus database with same CATH topology
1OPLA 2MRJA 1BLKA 3PSJA 1M61A 2HDVA 2HCKA 1O4BA 1SHDA 3OB1B 2DX0A 5GJIA 1BFJA 1CWDL 1MW4A 2LQNA 2DCRA 2K7AB 1O43A 1O4MA 3MXYA 1O4DA 3HHMB 2DLYA 2ETZA 4M4ZA 3GXWA 4QSYA 2K79B 2EYZA 4K44A 3VROA 3BUXB 1AYBA 2CI9A 4GWFA 1A1BA 3S8NA 1SPRA 1QCFA 1BHHA 1NRVA 4F5AA 2OZOA 2MC1A 1BMBA 3VS3A 1AYCA 2MRKA 1BLJA 5HKYA 1H9OA 1KA6A 2CBLA 1CWEA 3BKBA 1O4GA 3ZNIA 2B3OA 3K2MA 1FU6A 1R1QA 2RORA 4NWFA 1B47A 2YSXA 1O4HA 3OP0A 1OPKA 2YU7A 1BHHB 1KSWA 3GQIB 5BO4A 4OHIA 3T04A 4LUDA 2EL8A 2L6KA 3S9KA 1JWOA 3N84A 1BKLA 1WQUA 4E68A 4P9ZA 2LNWA 3BUOB 1NZLA 5DC0B 3MXCA 2LCTA 3IN7A 1O47A 3VGOA 1LCKA 1YVLA 2HMHA 4DGXA 3VS7A 3PLFB 1FHSA 1A81A 3US4A 2Y1MA 1JU5A 2KK6A 1ZFPE 4OHEA 3WA4A 3HIZB 3VS1A 3CWGA 1KA7A 1AOTF 5I6VA 1QG1E 1O4RA 1R1SA 2H46E 2PNBA 4K45A 2CI8A 4FL3A 1IS0A 1LUKA 4U17A 5IBMA 1JYQA 1G83A 2LQWA 1A09A 4F5BA 1YVHA 1O4CA 2Y1NA 2RSYA 3N8MA 2L4KA 1FU5A 1O4KA 4LUEA 2SHPA 3TKZA 1D4WA 3UF4A 4EIHA 3BUMB 2LNXA 1X0NA 1AD5A 4D8KA 2C0IA 3N7YA 3VS5A 1O45A 4OHDA 2CIAA 1O42A 5HKWA 3VS6A 4K11A 1A1CA 1Z3KA 5D0JA 4H1OA 3KFJA 3VS4A 1O48A 1X27A 3CBLA 3VRNA 4A4CA 3S8LA 3OV1A 4U1PA 5IBSA 4NWGA 1RJAA 3MAZA 2PNAA 2MK2A 1LUNA 1JYRA 1AYAA 3VRPA 1UURA 1RQQC 2GSBA 1UUSA 1K9AA 4K2RA 2ECDA 3NHNA 2SRCA 4XZ1A 1TCEA 1A1EA 3VRYA 3OVEA 1P13A 2C0OA 1FMKA 2EKXA 1X6CA 2L3TA 2EOBA 5J3XA 2AOBA 2EYYA 3PFVA 4FL2A 2PLDA 1O4JA 2H5KA 1BM2A 1HCSB 3VRQA 5DF6A 1RPYA 4EY0A 1KC2A 2CR4A 5EHRA 5AULA 1A07A 2HUWA 3VRZA 2C0TA 1GRIA 2MQIA 3BUNB 4FBNA 1CSZA 1Y57A 1AOUF 1SKJA 1O41A 1TZEE 3GXXA 2AUGA 2HDXA 4TZIA 1FYRA 2DLZA 4L1BB 4A4BA 2CRHA 1QADA 1IJRA 3C7IA 3HCKA 2C9WA 4GPLB 5DC9A 5GJHA 1CSYA 3BUWB 3EAZA 2FO0A 1I3ZA 2H8HA 3PSKA 4GL9E 2EYVA 2AOAA 2EO6A 3UYOA 3OB2B 5EEQA 2IUIA 1O4FA 1JYUA 3PJPA 1O4IA 4F59A 3S8OA 1GHUA 2VIFA 3IMJA 3QWYA 1HCTB 1OO3A 1LCJA 3VRRA 1OO4A 3M7FA 2CS0A 1Y1UA 1O4LA 1BHFA 2GE9A 1LUMA 4JGHA 1FBVA 1LKKA 3QWXX 5EG3B 1SPSA 5HKZA 2IUHA 2XP1A 2JYQA 2IUGA 1PICA 1A08A 1D4TA 4E93A 3CXLA 3CD3A 4OHHA 5EHPA 1SHBA 4P9VA 1BG1A 5DC4A 4H34A 1O4QA 1BFIA 2IZVA 2ABLA 2KNOA 4WWQA 3TL0A 3PS5A 1F1WA 2EO3A 1CJ1A 2RMXA 3PQZA 2EU0A 1D1ZA 1AYDA 1SHAA 4ROJA 2PTKA 1O44A 1O4AA 1XA6A 2PLEA 3EACA 4JEGA 1M27A 1O49A 3VS0A 4OHLA 2RVFA 5CDWA 2FCIA 1LKLA 1O4EA 1O4PA 2Y3AB 1O46A 5AXIA 1O4OA 1LUIA 2QMSA 5EELA 1BF5A 1BKMA 3IMDA 4X6SA 1MILA 2DM0A 4DGPA 1NZVA 1O4NA 1F2FA 1AB2A 2DVJA 2OQ1A 5KAZA 1A1AA 1R1PA 1FBZA 4XZ0A 4JE4A 2BBUA 3VS2A 3IN8A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1OPL A;  2MRJ A;  1BLK A;  3PSJ A;  1M61 A;  2HDV A;  2HCK A;  1O4B A;  1SHD A;  3OB1 B;  2DX0 A;  5GJI A;  1BFJ A;  1CWD L;  1MW4 A;  2LQN A;  2DCR A;  2K7A B;  1O43 A;  1O4M A;  3MXY A;  1O4D A;  3HHM B;  2DLY A;  2ETZ A;  4M4Z A;  3GXW A;  4QSY A;  2K79 B;  2EYZ A;  4K44 A;  3VRO A;  3BUX B;  1AYB A;  2CI9 A;  4GWF A;  1A1B A;  3S8N A;  1SPR A;  1QCF A;  1BHH A;  1NRV A;  4F5A A;  2OZO A;  2MC1 A;  1BMB A;  3VS3 A;  1AYC A;  2MRK A;  1BLJ A;  5HKY A;  1H9O A;  1KA6 A;  2CBL A;  1CWE A;  3BKB A;  1O4G A;  3ZNI A;  2B3O A;  3K2M A;  1FU6 A;  1R1Q A;  2ROR A;  4NWF A;  1B47 A;  2YSX A;  1O4H A;  3OP0 A;  1OPK A;  2YU7 A;  1BHH B;  1KSW A;  3GQI B;  5BO4 A;  4OHI A;  3T04 A;  4LUD A;  2EL8 A;  2L6K A;  3S9K A;  1JWO A;  3N84 A;  1BKL A;  1WQU A;  4E68 A;  4P9Z A;  2LNW A;  3BUO B;  1NZL A;  5DC0 B;  3MXC A;  2LCT A;  3IN7 A;  1O47 A;  3VGO A;  1LCK A;  1YVL A;  2HMH A;  4DGX A;  3VS7 A;  3PLF B;  1FHS A;  1A81 A;  3US4 A;  2Y1M A;  1JU5 A;  2KK6 A;  1ZFP E;  4OHE A;  3WA4 A;  3HIZ B;  3VS1 A;  3CWG A;  1KA7 A;  1AOT F;  5I6V A;  1QG1 E;  1O4R A;  1R1S A;  2H46 E;  2PNB A;  4K45 A;  2CI8 A;  4FL3 A;  1IS0 A;  1LUK A;  4U17 A;  5IBM A;  1JYQ A;  1G83 A;  2LQW A;  1A09 A;  4F5B A;  1YVH A;  1O4C A;  2Y1N A;  2RSY A;  3N8M A;  2L4K A;  1FU5 A;  1O4K A;  4LUE A;  2SHP A;  3TKZ A;  1D4W A;  3UF4 A;  4EIH A;  3BUM B;  2LNX A;  1X0N A;  1AD5 A;  4D8K A;  2C0I A;  3N7Y A;  3VS5 A;  1O45 A;  4OHD A;  2CIA A;  1O42 A;  5HKW A;  3VS6 A;  4K11 A;  1A1C A;  1Z3K A;  5D0J A;  4H1O A;  3KFJ A;  3VS4 A;  1O48 A;  1X27 A;  3CBL A;  3VRN A;  4A4C A;  3S8L A;  3OV1 A;  4U1P A;  5IBS A;  4NWG A;  1RJA A;  3MAZ A;  2PNA A;  2MK2 A;  1LUN A;  1JYR A;  1AYA A;  3VRP A;  1UUR A;  1RQQ C;  2GSB A;  1UUS A;  1K9A A;  4K2R A;  2ECD A;  3NHN A;  2SRC A;  4XZ1 A;  1TCE A;  1A1E A;  3VRY A;  3OVE A;  1P13 A;  2C0O A;  1FMK A;  2EKX A;  1X6C A;  2L3T A;  2EOB A;  5J3X A;  2AOB A;  2EYY A;  3PFV A;  4FL2 A;  2PLD A;  1O4J A;  2H5K A;  1BM2 A;  1HCS B;  3VRQ A;  5DF6 A;  1RPY A;  4EY0 A;  1KC2 A;  2CR4 A;  5EHR A;  5AUL A;  1A07 A;  2HUW A;  3VRZ A;  2C0T A;  1GRI A;  2MQI A;  3BUN B;  4FBN A;  1CSZ A;  1Y57 A;  1AOU F;  1SKJ A;  1O41 A;  1TZE E;  3GXX A;  2AUG A;  2HDX A;  4TZI A;  1FYR A;  2DLZ A;  4L1B B;  4A4B A;  2CRH A;  1QAD A;  1IJR A;  3C7I A;  3HCK A;  2C9W A;  4GPL B;  5DC9 A;  5GJH A;  1CSY A;  3BUW B;  3EAZ A;  2FO0 A;  1I3Z A;  2H8H A;  3PSK A;  4GL9 E;  2EYV A;  2AOA A;  2EO6 A;  3UYO A;  3OB2 B;  5EEQ A;  2IUI A;  1O4F A;  1JYU A;  3PJP A;  1O4I A;  4F59 A;  3S8O A;  1GHU A;  2VIF A;  3IMJ A;  3QWY A;  1HCT B;  1OO3 A;  1LCJ A;  3VRR A;  1OO4 A;  3M7F A;  2CS0 A;  1Y1U A;  1O4L A;  1BHF A;  2GE9 A;  1LUM A;  4JGH A;  1FBV A;  1LKK A;  3QWX X;  5EG3 B;  1SPS A;  5HKZ A;  2IUH A;  2XP1 A;  2JYQ A;  2IUG A;  1PIC A;  1A08 A;  1D4T A;  4E93 A;  3CXL A;  3CD3 A;  4OHH A;  5EHP A;  1SHB A;  4P9V A;  1BG1 A;  5DC4 A;  4H34 A;  1O4Q A;  1BFI A;  2IZV A;  2ABL A;  2KNO A;  4WWQ A;  3TL0 A;  3PS5 A;  1F1W A;  2EO3 A;  1CJ1 A;  2RMX A;  3PQZ A;  2EU0 A;  1D1Z A;  1AYD A;  1SHA A;  4ROJ A;  2PTK A;  1O44 A;  1O4A A;  1XA6 A;  2PLE A;  3EAC A;  4JEG A;  1M27 A;  1O49 A;  3VS0 A;  4OHL A;  2RVF A;  5CDW A;  2FCI A;  1LKL A;  1O4E A;  1O4P A;  2Y3A B;  1O46 A;  5AXI A;  1O4O A;  1LUI A;  2QMS A;  5EEL A;  1BF5 A;  1BKM A;  3IMD A;  4X6S A;  1MIL A;  2DM0 A;  4DGP A;  1NZV A;  1O4N A;  1F2F A;  1AB2 A;  2DVJ A;  2OQ1 A;  5KAZ A;  1A1A A;  1R1P A;  1FBZ A;  4XZ0 A;  4JE4 A;  2BBU A;  3VS2 A;  3IN8 A; 
#chains in the Genus database with same CATH topology
 1OPL A;  2MRJ A;  1BLK A;  3PSJ A;  1M61 A;  2HDV A;  2HCK A;  1O4B A;  1SHD A;  3OB1 B;  2DX0 A;  5GJI A;  1BFJ A;  1CWD L;  1MW4 A;  2LQN A;  2DCR A;  2K7A B;  1O43 A;  1O4M A;  3MXY A;  1O4D A;  3HHM B;  2DLY A;  2ETZ A;  4M4Z A;  3GXW A;  4QSY A;  2K79 B;  2EYZ A;  4K44 A;  3VRO A;  3BUX B;  1AYB A;  2CI9 A;  4GWF A;  1A1B A;  3S8N A;  1SPR A;  1QCF A;  1BHH A;  1NRV A;  4F5A A;  2OZO A;  2MC1 A;  1BMB A;  3VS3 A;  1AYC A;  2MRK A;  1BLJ A;  5HKY A;  1H9O A;  1KA6 A;  2CBL A;  1CWE A;  3BKB A;  1O4G A;  3ZNI A;  2B3O A;  3K2M A;  1FU6 A;  1R1Q A;  2ROR A;  4NWF A;  1B47 A;  2YSX A;  1O4H A;  3OP0 A;  1OPK A;  2YU7 A;  1BHH B;  1KSW A;  3GQI B;  5BO4 A;  4OHI A;  3T04 A;  4LUD A;  2EL8 A;  2L6K A;  3S9K A;  1JWO A;  3N84 A;  1BKL A;  1WQU A;  4E68 A;  4P9Z A;  2LNW A;  3BUO B;  1NZL A;  5DC0 B;  3MXC A;  2LCT A;  3K2T A;  3IN7 A;  1O47 A;  3VGO A;  1LCK A;  1YVL A;  2HMH A;  4DGX A;  3VS7 A;  3PLF B;  1FHS A;  1A81 A;  3US4 A;  2Y1M A;  1JU5 A;  2KK6 A;  1ZFP E;  4OHE A;  3WA4 A;  3HIZ B;  3VS1 A;  3CWG A;  1KA7 A;  1AOT F;  5I6V A;  1QG1 E;  1O4R A;  1R1S A;  2H46 E;  2PNB A;  4K45 A;  2CI8 A;  4FL3 A;  1IS0 A;  1LUK A;  4U17 A;  5IBM A;  1JYQ A;  1G83 A;  2LQW A;  1A09 A;  4F5B A;  1YVH A;  1O4C A;  2Y1N A;  2RSY A;  3N8M A;  2L4K A;  1FU5 A;  1O4K A;  4LUE A;  2SHP A;  3TKZ A;  1D4W A;  3UF4 A;  4EIH A;  3BUM B;  2LNX A;  1X0N A;  1AD5 A;  4D8K A;  2C0I A;  3N7Y A;  3VS5 A;  1O45 A;  4OHD A;  2CIA A;  1O42 A;  5HKW A;  3VS6 A;  4K11 A;  1A1C A;  1Z3K A;  5D0J A;  4H1O A;  3KFJ A;  3VS4 A;  1O48 A;  1X27 A;  3CBL A;  3VRN A;  4A4C A;  3S8L A;  3OV1 A;  4U1P A;  5IBS A;  4NWG A;  1RJA A;  3MAZ A;  2PNA A;  2MK2 A;  1LUN A;  1JYR A;  1AYA A;  3VRP A;  1UUR A;  1RQQ C;  2GSB A;  1UUS A;  1K9A A;  4K2R A;  2ECD A;  3NHN A;  2SRC A;  4XZ1 A;  1TCE A;  1A1E A;  3VRY A;  3OVE A;  3LYV A;  1P13 A;  2C0O A;  1FMK A;  2EKX A;  1X6C A;  2L3T A;  2EOB A;  5J3X A;  2AOB A;  2EYY A;  3PFV A;  4FL2 A;  2PLD A;  1O4J A;  2H5K A;  1BM2 A;  1HCS B;  3VRQ A;  5DF6 A;  1RPY A;  4EY0 A;  1KC2 A;  2CR4 A;  5EHR A;  5AUL A;  1A07 A;  2HUW A;  3VRZ A;  2C0T A;  1GRI A;  2MQI A;  3BUN B;  4FBN A;  1CSZ A;  1Y57 A;  1AOU F;  1SKJ A;  1O41 A;  1TZE E;  3GXX A;  2AUG A;  2HDX A;  2LRA A;  4TZI A;  1FYR A;  2DLZ A;  4L1B B;  4A4B A;  2CRH A;  1QAD A;  1IJR A;  3C7I A;  3HCK A;  2C9W A;  4GPL B;  5DC9 A;  5GJH A;  1CSY A;  3BUW B;  3EAZ A;  2FO0 A;  1I3Z A;  2H8H A;  3PSK A;  4GL9 E;  2EYV A;  2AOA A;  2EO6 A;  3UYO A;  3OB2 B;  5EEQ A;  2IUI A;  1O4F A;  1JYU A;  3PJP A;  1O4I A;  4F59 A;  3S8O A;  1GHU A;  2VIF A;  3IMJ A;  3QWY A;  1HCT B;  1OO3 A;  1LCJ A;  3VRR A;  1OO4 A;  3M7F A;  2CS0 A;  1Y1U A;  1O4L A;  1BHF A;  2GE9 A;  1LUM A;  4JGH A;  1FBV A;  1LKK A;  3QWX X;  5EG3 B;  1SPS A;  5HKZ A;  2IUH A;  2XP1 A;  2JYQ A;  2IUG A;  1PIC A;  1A08 A;  1D4T A;  4E93 A;  3CXL A;  3CD3 A;  4OHH A;  5EHP A;  1SHB A;  4P9V A;  1BG1 A;  5DC4 A;  4H34 A;  1O4Q A;  1BFI A;  2IZV A;  2ABL A;  2KNO A;  4WWQ A;  3TL0 A;  3PS5 A;  1F1W A;  2EO3 A;  1CJ1 A;  2RMX A;  3PQZ A;  2EU0 A;  1D1Z A;  1AYD A;  1SHA A;  2KGY A;  4ROJ A;  2PTK A;  1O44 A;  1O4A A;  1XA6 A;  2PLE A;  3EAC A;  4JEG A;  1M27 A;  1O49 A;  3VS0 A;  4OHL A;  2RVF A;  5CDW A;  2FCI A;  1LKL A;  1O4E A;  1O4P A;  2Y3A B;  1O46 A;  5AXI A;  1O4O A;  1LUI A;  2QMS A;  5EEL A;  1BF5 A;  1BKM A;  3IMD A;  4X6S A;  1MIL A;  2DM0 A;  4DGP A;  1NZV A;  1O4N A;  1F2F A;  1AB2 A;  2DVJ A;  2OQ1 A;  5KAZ A;  1A1A A;  1R1P A;  1FBZ A;  4XZ0 A;  4JE4 A;  2BBU A;  3VS2 A;  3IN8 A; 
#chains in the Genus database with same CATH homology
 1OPL A;  2MRJ A;  1BLK A;  3PSJ A;  1M61 A;  2HDV A;  2HCK A;  1O4B A;  1SHD A;  3OB1 B;  2DX0 A;  5GJI A;  1BFJ A;  1CWD L;  1MW4 A;  2LQN A;  2DCR A;  2K7A B;  1O43 A;  1O4M A;  3MXY A;  1O4D A;  3HHM B;  2DLY A;  2ETZ A;  4M4Z A;  3GXW A;  4QSY A;  2K79 B;  2EYZ A;  4K44 A;  3VRO A;  3BUX B;  1AYB A;  2CI9 A;  4GWF A;  1A1B A;  3S8N A;  1SPR A;  1QCF A;  1BHH A;  1NRV A;  4F5A A;  2OZO A;  2MC1 A;  1BMB A;  3VS3 A;  1AYC A;  2MRK A;  1BLJ A;  5HKY A;  1H9O A;  1KA6 A;  2CBL A;  1CWE A;  3BKB A;  1O4G A;  3ZNI A;  2B3O A;  3K2M A;  1FU6 A;  1R1Q A;  2ROR A;  4NWF A;  1B47 A;  2YSX A;  1O4H A;  3OP0 A;  1OPK A;  2YU7 A;  1BHH B;  1KSW A;  3GQI B;  5BO4 A;  4OHI A;  3T04 A;  4LUD A;  2EL8 A;  2L6K A;  3S9K A;  1JWO A;  3N84 A;  1BKL A;  1WQU A;  4E68 A;  4P9Z A;  2LNW A;  3BUO B;  1NZL A;  5DC0 B;  3MXC A;  2LCT A;  3IN7 A;  1O47 A;  3VGO A;  1LCK A;  1YVL A;  2HMH A;  4DGX A;  3VS7 A;  3PLF B;  1FHS A;  1A81 A;  3US4 A;  2Y1M A;  1JU5 A;  2KK6 A;  1ZFP E;  4OHE A;  3WA4 A;  3HIZ B;  3VS1 A;  3CWG A;  1KA7 A;  1AOT F;  5I6V A;  1QG1 E;  1O4R A;  1R1S A;  2H46 E;  2PNB A;  4K45 A;  2CI8 A;  4FL3 A;  1IS0 A;  1LUK A;  4U17 A;  5IBM A;  1JYQ A;  1G83 A;  2LQW A;  1A09 A;  4F5B A;  1YVH A;  1O4C A;  2Y1N A;  2RSY A;  3N8M A;  2L4K A;  1FU5 A;  1O4K A;  4LUE A;  2SHP A;  3TKZ A;  1D4W A;  3UF4 A;  4EIH A;  3BUM B;  2LNX A;  1X0N A;  1AD5 A;  4D8K A;  2C0I A;  3N7Y A;  3VS5 A;  1O45 A;  4OHD A;  2CIA A;  1O42 A;  5HKW A;  3VS6 A;  4K11 A;  1A1C A;  1Z3K A;  5D0J A;  4H1O A;  3KFJ A;  3VS4 A;  1O48 A;  1X27 A;  3CBL A;  3VRN A;  4A4C A;  3S8L A;  3OV1 A;  4U1P A;  5IBS A;  4NWG A;  1RJA A;  3MAZ A;  2PNA A;  2MK2 A;  1LUN A;  1JYR A;  1AYA A;  3VRP A;  1UUR A;  1RQQ C;  2GSB A;  1UUS A;  1K9A A;  4K2R A;  2ECD A;  3NHN A;  2SRC A;  4XZ1 A;  1TCE A;  1A1E A;  3VRY A;  3OVE A;  1P13 A;  2C0O A;  1FMK A;  2EKX A;  1X6C A;  2L3T A;  2EOB A;  5J3X A;  2AOB A;  2EYY A;  3PFV A;  4FL2 A;  2PLD A;  1O4J A;  2H5K A;  1BM2 A;  1HCS B;  3VRQ A;  5DF6 A;  1RPY A;  4EY0 A;  1KC2 A;  2CR4 A;  5EHR A;  5AUL A;  1A07 A;  2HUW A;  3VRZ A;  2C0T A;  1GRI A;  2MQI A;  3BUN B;  4FBN A;  1CSZ A;  1Y57 A;  1AOU F;  1SKJ A;  1O41 A;  1TZE E;  3GXX A;  2AUG A;  2HDX A;  4TZI A;  1FYR A;  2DLZ A;  4L1B B;  4A4B A;  2CRH A;  1QAD A;  1IJR A;  3C7I A;  3HCK A;  2C9W A;  4GPL B;  5DC9 A;  5GJH A;  1CSY A;  3BUW B;  3EAZ A;  2FO0 A;  1I3Z A;  2H8H A;  3PSK A;  4GL9 E;  2EYV A;  2AOA A;  2EO6 A;  3UYO A;  3OB2 B;  5EEQ A;  2IUI A;  1O4F A;  1JYU A;  3PJP A;  1O4I A;  4F59 A;  3S8O A;  1GHU A;  2VIF A;  3IMJ A;  3QWY A;  1HCT B;  1OO3 A;  1LCJ A;  3VRR A;  1OO4 A;  3M7F A;  2CS0 A;  1Y1U A;  1O4L A;  1BHF A;  2GE9 A;  1LUM A;  4JGH A;  1FBV A;  1LKK A;  3QWX X;  5EG3 B;  1SPS A;  5HKZ A;  2IUH A;  2XP1 A;  2JYQ A;  2IUG A;  1PIC A;  1A08 A;  1D4T A;  4E93 A;  3CXL A;  3CD3 A;  4OHH A;  5EHP A;  1SHB A;  4P9V A;  1BG1 A;  5DC4 A;  4H34 A;  1O4Q A;  1BFI A;  2IZV A;  2ABL A;  2KNO A;  4WWQ A;  3TL0 A;  3PS5 A;  1F1W A;  2EO3 A;  1CJ1 A;  2RMX A;  3PQZ A;  2EU0 A;  1D1Z A;  1AYD A;  1SHA A;  4ROJ A;  2PTK A;  1O44 A;  1O4A A;  1XA6 A;  2PLE A;  3EAC A;  4JEG A;  1M27 A;  1O49 A;  3VS0 A;  4OHL A;  2RVF A;  5CDW A;  2FCI A;  1LKL A;  1O4E A;  1O4P A;  2Y3A B;  1O46 A;  5AXI A;  1O4O A;  1LUI A;  2QMS A;  5EEL A;  1BF5 A;  1BKM A;  3IMD A;  4X6S A;  1MIL A;  2DM0 A;  4DGP A;  1NZV A;  1O4N A;  1F2F A;  1AB2 A;  2DVJ A;  2OQ1 A;  5KAZ A;  1A1A A;  1R1P A;  1FBZ A;  4XZ0 A;  4JE4 A;  2BBU A;  3VS2 A;  3IN8 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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