2PNAA

Structure of an sh2 domain of the p85 alpha subunit of phosphatidylinositol-3-oh kinase
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
104
structure length
104
Chain Sequence
LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signalling protein
source organism Bos taurus
publication title Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.
pubmed doi rcsb
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL S
total genus 8
structure length 104
sequence length 104
ec nomenclature ec 2.7.1.137: Phosphatidylinositol 3-kinase.
pdb deposition date 1992-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2pnaA00
2LQWA 1O4LA 1AYBA 1O41A 5HKWA 1CWDL 3VRZA 3VS1A 3VS4A 5DC9A 3PS5A 4M4ZA 1ZFPE 1BHHB 3VS6A 4JEGA 2H8HA 2DX0A 1O4KA 2EO3A 1OO4A 5DF6A 3IMJA 1P13A 3VRPA 1PICA 1D4WA 1YVHA 2GE9A 2EYYA 1K9AA 3KFJA 1I3ZA 2PLEA 1O4HA 1AD5A 1LCJA 2K7AB 3IN8A 2C0TA 1G83A 2KNOA 3EAZA 1X27A 3K2MA 1MILA 5HKZA 3HHMB 4JGHA 3UYOA 4DGPA 1A81A 2ETZA 1BHFA 1O42A 2DCRA 1O47A 3S8NA 1O4CA 2B3OA 5D0JA 1NZLA 1BLJA 1GHUA 1D1ZA 4JE4A 1F1WA 3VROA 1BKMA 2RORA 1R1SA 3OB1B 5J3XA 1LKKA 1O44A 2HMHA 1X0NA 1MW4A 4FBNA 4P9VA 1BKLA 1O45A 2DLYA 3VRQA 2PNAA 3VS5A 3PLFB 3HCKA 2VIFA 5DC0B 1JYQA 1A1CA 1AB2A 4F59A 1O4RA 2PTKA 3VRYA 1NRVA 5CDWA 3VS0A 1HCSB 3BUNB 2MRKA 1Y1UA 1H9OA 2DM0A 5BO4A 2YSXA 1O4MA 2CIAA 2SRCA 4F5AA 3US4A 4K44A 4A4BA 1LUIA 3VRNA 4TZIA 1LUMA 1FU5A 1QCFA 5IBSA 4GPLB 2RSYA 4OHEA 2CR4A 1RQQC 3OP0A 2EYZA 1FYRA 2QMSA 1BMBA 2CBLA 1O4FA 1O4GA 3TKZA 1BG1A 2LQNA 3QWYA 2Y3AB 1UUSA 2YU7A 1A1AA 3PSJA 2IUGA 2JYQA 1B47A 1RPYA 1KC2A 1BLKA 2EL8A 3GXXA 2AUGA 1O4IA 2MQIA 4NWGA 1SHAA 3OVEA 1SPSA 1KA7A 5EHRA 3OV1A 1OPKA 5AXIA 3ZNIA 1SHBA 4K11A 2K79B 1QG1E 3IN7A 4LUDA 2IUIA 2LNWA 1Y57A 2RMXA 1O4NA 1R1QA 1O4JA 2SHPA 4U1PA 5GJIA 3EACA 1AYCA 1O4EA 4X6SA 3BUXB 3MXYA 3CWGA 1OO3A 5DC4A 2MC1A 1AOUF 1AYAA 1O46A 1FHSA 4XZ0A 1JU5A 1SHDA 3CD3A 1A07A 3C7IA 5EEQA 1A1BA 1JWOA 3GQIB 4A4CA 1LCKA 1GRIA 2EO6A 1FBZA 1O4AA 2L6KA 1AOTF 3S9KA 1LUNA 4DGXA 2Y1NA 2FCIA 1R1PA 2AOAA 3TL0A 2C0OA 2EKXA 2MK2A 1A1EA 5IBMA 1KA6A 1O48A 2PLDA 1D4TA 1FU6A 4H34A 1LUKA 1A08A 4NWFA 3GXWA 4E93A 1BF5A 4F5BA 3BUMB 4FL2A 1X6CA 3S8LA 3VRRA 2H46E 2GSBA 5GJHA 2MRJA 1XA6A 3N84A 3BUWB 1F2FA 2C0IA 3BKBA 2OQ1A 4P9ZA 1CSZA 4H1OA 4E68A 1HCTB 1IS0A 1IJRA 2IUHA 5HKYA 1O4QA 4GWFA 4GL9E 1SKJA 2L4KA 2PNBA 4FL3A 4WWQA 1O4OA 1JYUA 3MAZA 2LCTA 2Y1MA 3VS3A 3OB2B 2EYVA 1A09A 1NZVA 1CJ1A 5EG3B 1WQUA 1BM2A 1O43A 2OZOA 4OHHA 4XZ1A 3T04A 1O4BA 3VS2A 4QSYA 2XP1A 1BFJA 1O49A 1JYRA 3WA4A 2CRHA 1OPLA 2ABLA 5I6VA 2HDXA 1M61A 3N7YA 5EELA 1TCEA 3VS7A 2DVJA 3BUOB 1M27A 2C9WA 1AYDA 2L3TA 2CS0A 2H5KA 2CI8A 2HUWA 3VGOA 1Z3KA 1O4DA 3PFVA 4K2RA 2HCKA 4K45A 4EY0A 4ROJA 1UURA 2CI9A 3M7FA 2KK6A 1YVLA 3PSKA 2LNXA 3MXCA 4LUEA 1LKLA 1RJAA 3HIZB 4EIHA 1CSYA 2EU0A 1CWEA 3UF4A 2AOBA 1FMKA 4OHIA 2BBUA 5EHPA 3QWXX 2IZVA 3S8OA 3N8MA 1BFIA 3CBLA 3NHNA 1QADA 4L1BB 2EOBA 1SPRA 1KSWA 3IMDA 4D8KA 3PJPA 2FO0A 2RVFA 3PQZA 5AULA 1O4PA 1BHHA 5KAZA 2HDVA 3CXLA 1FBVA 2ECDA 4U17A 4OHDA 4OHLA 2DLZA 1TZEE
chains in the Genus database with same CATH superfamily
2LQWA 1O4LA 1AYBA 1O41A 5HKWA 1CWDL 3VRZA 3VS1A 3VS4A 5DC9A 3PS5A 4M4ZA 1ZFPE 1BHHB 3VS6A 4JEGA 2H8HA 2DX0A 1O4KA 2EO3A 1OO4A 5DF6A 3IMJA 1P13A 3VRPA 1PICA 1D4WA 1YVHA 2GE9A 2EYYA 1K9AA 3KFJA 1I3ZA 2PLEA 1O4HA 1AD5A 1LCJA 2K7AB 3IN8A 2C0TA 1G83A 2KNOA 3EAZA 1X27A 3K2MA 1MILA 5HKZA 3HHMB 4JGHA 3UYOA 4DGPA 1A81A 2ETZA 1BHFA 1O42A 2DCRA 1O47A 3S8NA 1O4CA 2B3OA 5D0JA 1NZLA 1BLJA 1GHUA 1D1ZA 4JE4A 1F1WA 3VROA 1BKMA 2RORA 1R1SA 3OB1B 5J3XA 1LKKA 2KGYA 1O44A 2HMHA 1X0NA 1MW4A 4FBNA 4P9VA 1BKLA 1O45A 2DLYA 3VRQA 2PNAA 3VS5A 3PLFB 3HCKA 2VIFA 5DC0B 1JYQA 1A1CA 1AB2A 4F59A 1O4RA 2PTKA 3VRYA 1NRVA 5CDWA 3VS0A 1HCSB 3BUNB 2MRKA 1Y1UA 1H9OA 2DM0A 5BO4A 2YSXA 1O4MA 2CIAA 2SRCA 4F5AA 3US4A 4K44A 4A4BA 1LUIA 3VRNA 4TZIA 1LUMA 1FU5A 1QCFA 5IBSA 4GPLB 2RSYA 4OHEA 2CR4A 1RQQC 3OP0A 2EYZA 1FYRA 2QMSA 1BMBA 2CBLA 1O4FA 1O4GA 3TKZA 1BG1A 2LQNA 3QWYA 2Y3AB 1UUSA 2YU7A 1A1AA 3PSJA 2IUGA 2JYQA 1B47A 1RPYA 1KC2A 1BLKA 2EL8A 3GXXA 2AUGA 1O4IA 3LYVA 2MQIA 4NWGA 1SHAA 3OVEA 1SPSA 1KA7A 5EHRA 3OV1A 1OPKA 5AXIA 3ZNIA 1SHBA 4K11A 2K79B 1QG1E 3IN7A 4LUDA 2IUIA 2LNWA 1Y57A 2RMXA 1O4NA 1R1QA 1O4JA 2SHPA 4U1PA 5GJIA 3EACA 1AYCA 1O4EA 4X6SA 3BUXB 3MXYA 3CWGA 1OO3A 5DC4A 2MC1A 1AOUF 1AYAA 1O46A 1FHSA 4XZ0A 1JU5A 1SHDA 3CD3A 1A07A 3C7IA 5EEQA 1A1BA 1JWOA 3GQIB 4A4CA 1LCKA 1GRIA 2EO6A 1FBZA 1O4AA 2L6KA 1AOTF 3S9KA 1LUNA 4DGXA 2Y1NA 2FCIA 1R1PA 2AOAA 3TL0A 2C0OA 2EKXA 2MK2A 1A1EA 5IBMA 1KA6A 1O48A 2PLDA 1D4TA 1FU6A 4H34A 1LUKA 1A08A 4NWFA 3GXWA 4E93A 1BF5A 4F5BA 3BUMB 4FL2A 1X6CA 3S8LA 3VRRA 2H46E 2GSBA 5GJHA 2MRJA 1XA6A 3N84A 3BUWB 1F2FA 2C0IA 3BKBA 2OQ1A 4P9ZA 1CSZA 4H1OA 4E68A 1HCTB 1IS0A 1IJRA 2IUHA 5HKYA 1O4QA 4GWFA 4GL9E 1SKJA 2L4KA 2PNBA 4FL3A 4WWQA 1O4OA 1JYUA 3MAZA 2LCTA 2Y1MA 3VS3A 3OB2B 2EYVA 1A09A 1NZVA 1CJ1A 5EG3B 1WQUA 1BM2A 1O43A 2OZOA 4OHHA 4XZ1A 3T04A 1O4BA 3VS2A 4QSYA 2XP1A 1BFJA 1O49A 1JYRA 3K2TA 3WA4A 2CRHA 1OPLA 2ABLA 5I6VA 2HDXA 1M61A 3N7YA 5EELA 1TCEA 3VS7A 2DVJA 3BUOB 1M27A 2C9WA 1AYDA 2L3TA 2CS0A 2H5KA 2CI8A 2HUWA 3VGOA 1Z3KA 1O4DA 3PFVA 4K2RA 2HCKA 4K45A 4EY0A 4ROJA 1UURA 2CI9A 3M7FA 2LRAA 2KK6A 1YVLA 3PSKA 2LNXA 3MXCA 4LUEA 1LKLA 1RJAA 3HIZB 4EIHA 1CSYA 2EU0A 1CWEA 3UF4A 2AOBA 1FMKA 4OHIA 2BBUA 5EHPA 3QWXX 2IZVA 3S8OA 3N8MA 1BFIA 3CBLA 3NHNA 1QADA 4L1BB 2EOBA 1SPRA 1KSWA 3IMDA 4D8KA 3PJPA 2FO0A 2RVFA 3PQZA 5AULA 1O4PA 1BHHA 5KAZA 2HDVA 3CXLA 1FBVA 2ECDA 4U17A 4OHDA 4OHLA 2DLZA 1TZEE
chains in the Genus database with same CATH topology
2LQWA 1O4LA 1AYBA 1O41A 5HKWA 1CWDL 3VRZA 3VS1A 3VS4A 5DC9A 3PS5A 4M4ZA 1ZFPE 1BHHB 3VS6A 4JEGA 2H8HA 2DX0A 1O4KA 2EO3A 1OO4A 5DF6A 3IMJA 1P13A 3VRPA 1PICA 1D4WA 1YVHA 2GE9A 2EYYA 1K9AA 3KFJA 1I3ZA 2PLEA 1O4HA 1AD5A 1LCJA 2K7AB 3IN8A 2C0TA 1G83A 2KNOA 3EAZA 1X27A 3K2MA 1MILA 5HKZA 3HHMB 4JGHA 3UYOA 4DGPA 1A81A 2ETZA 1BHFA 1O42A 2DCRA 1O47A 3S8NA 1O4CA 2B3OA 5D0JA 1NZLA 1BLJA 1GHUA 1D1ZA 4JE4A 1F1WA 3VROA 1BKMA 2RORA 1R1SA 3OB1B 5J3XA 1LKKA 1O44A 2HMHA 1X0NA 1MW4A 4FBNA 4P9VA 1BKLA 1O45A 2DLYA 3VRQA 2PNAA 3VS5A 3PLFB 3HCKA 2VIFA 5DC0B 1JYQA 1A1CA 1AB2A 4F59A 1O4RA 2PTKA 3VRYA 1NRVA 5CDWA 3VS0A 1HCSB 3BUNB 2MRKA 1Y1UA 1H9OA 2DM0A 5BO4A 2YSXA 1O4MA 2CIAA 2SRCA 4F5AA 3US4A 4K44A 4A4BA 1LUIA 3VRNA 4TZIA 1LUMA 1FU5A 1QCFA 5IBSA 4GPLB 2RSYA 4OHEA 2CR4A 1RQQC 3OP0A 2EYZA 1FYRA 2QMSA 1BMBA 2CBLA 1O4FA 1O4GA 3TKZA 1BG1A 2LQNA 3QWYA 2Y3AB 1UUSA 2YU7A 1A1AA 3PSJA 2IUGA 2JYQA 1B47A 1RPYA 1KC2A 1BLKA 2EL8A 3GXXA 2AUGA 1O4IA 2MQIA 4NWGA 1SHAA 3OVEA 1SPSA 1KA7A 5EHRA 3OV1A 1OPKA 5AXIA 3ZNIA 1SHBA 4K11A 2K79B 1QG1E 3IN7A 4LUDA 2IUIA 2LNWA 1Y57A 2RMXA 1O4NA 1R1QA 1O4JA 2SHPA 4U1PA 5GJIA 3EACA 1AYCA 1O4EA 4X6SA 3BUXB 3MXYA 3CWGA 1OO3A 5DC4A 2MC1A 1AOUF 1AYAA 1O46A 1FHSA 4XZ0A 1JU5A 1SHDA 3CD3A 1A07A 3C7IA 5EEQA 1A1BA 1JWOA 3GQIB 4A4CA 1LCKA 1GRIA 2EO6A 1FBZA 1O4AA 2L6KA 1AOTF 3S9KA 1LUNA 4DGXA 2Y1NA 2FCIA 1R1PA 2AOAA 3TL0A 2C0OA 2EKXA 2MK2A 1A1EA 5IBMA 1KA6A 1O48A 2PLDA 1D4TA 1FU6A 4H34A 1LUKA 1A08A 4NWFA 3GXWA 4E93A 1BF5A 4F5BA 3BUMB 4FL2A 1X6CA 3S8LA 3VRRA 2H46E 2GSBA 5GJHA 2MRJA 1XA6A 3N84A 3BUWB 1F2FA 2C0IA 3BKBA 2OQ1A 4P9ZA 1CSZA 4H1OA 4E68A 1HCTB 1IS0A 1IJRA 2IUHA 5HKYA 1O4QA 4GWFA 4GL9E 1SKJA 2L4KA 2PNBA 4FL3A 4WWQA 1O4OA 1JYUA 3MAZA 2LCTA 2Y1MA 3VS3A 3OB2B 2EYVA 1A09A 1NZVA 1CJ1A 5EG3B 1WQUA 1BM2A 1O43A 2OZOA 4OHHA 4XZ1A 3T04A 1O4BA 3VS2A 4QSYA 2XP1A 1BFJA 1O49A 1JYRA 3WA4A 2CRHA 1OPLA 2ABLA 5I6VA 2HDXA 1M61A 3N7YA 5EELA 1TCEA 3VS7A 2DVJA 3BUOB 1M27A 2C9WA 1AYDA 2L3TA 2CS0A 2H5KA 2CI8A 2HUWA 3VGOA 1Z3KA 1O4DA 3PFVA 4K2RA 2HCKA 4K45A 4EY0A 4ROJA 1UURA 2CI9A 3M7FA 2KK6A 1YVLA 3PSKA 2LNXA 3MXCA 4LUEA 1LKLA 1RJAA 3HIZB 4EIHA 1CSYA 2EU0A 1CWEA 3UF4A 2AOBA 1FMKA 4OHIA 2BBUA 5EHPA 3QWXX 2IZVA 3S8OA 3N8MA 1BFIA 3CBLA 3NHNA 1QADA 4L1BB 2EOBA 1SPRA 1KSWA 3IMDA 4D8KA 3PJPA 2FO0A 2RVFA 3PQZA 5AULA 1O4PA 1BHHA 5KAZA 2HDVA 3CXLA 1FBVA 2ECDA 4U17A 4OHDA 4OHLA 2DLZA 1TZEE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LQW A;  1O4L A;  1AYB A;  1O41 A;  5HKW A;  1CWD L;  3VRZ A;  3VS1 A;  3VS4 A;  5DC9 A;  3PS5 A;  4M4Z A;  1ZFP E;  1BHH B;  3VS6 A;  4JEG A;  2H8H A;  2DX0 A;  1O4K A;  2EO3 A;  1OO4 A;  5DF6 A;  3IMJ A;  1P13 A;  3VRP A;  1PIC A;  1D4W A;  1YVH A;  2GE9 A;  2EYY A;  1K9A A;  3KFJ A;  1I3Z A;  2PLE A;  1O4H A;  1AD5 A;  1LCJ A;  2K7A B;  3IN8 A;  2C0T A;  1G83 A;  2KNO A;  3EAZ A;  1X27 A;  3K2M A;  1MIL A;  5HKZ A;  3HHM B;  4JGH A;  3UYO A;  4DGP A;  1A81 A;  2ETZ A;  1BHF A;  1O42 A;  2DCR A;  1O47 A;  3S8N A;  1O4C A;  2B3O A;  5D0J A;  1NZL A;  1BLJ A;  1GHU A;  1D1Z A;  4JE4 A;  1F1W A;  3VRO A;  1BKM A;  2ROR A;  1R1S A;  3OB1 B;  5J3X A;  1LKK A;  1O44 A;  2HMH A;  1X0N A;  1MW4 A;  4FBN A;  4P9V A;  1BKL A;  1O45 A;  2DLY A;  3VRQ A;  2PNA A;  3VS5 A;  3PLF B;  3HCK A;  2VIF A;  5DC0 B;  1JYQ A;  1A1C A;  1AB2 A;  4F59 A;  1O4R A;  2PTK A;  3VRY A;  1NRV A;  5CDW A;  3VS0 A;  1HCS B;  3BUN B;  2MRK A;  1Y1U A;  1H9O A;  2DM0 A;  5BO4 A;  2YSX A;  1O4M A;  2CIA A;  2SRC A;  4F5A A;  3US4 A;  4K44 A;  4A4B A;  1LUI A;  3VRN A;  4TZI A;  1LUM A;  1FU5 A;  1QCF A;  5IBS A;  4GPL B;  2RSY A;  4OHE A;  2CR4 A;  1RQQ C;  3OP0 A;  2EYZ A;  1FYR A;  2QMS A;  1BMB A;  2CBL A;  1O4F A;  1O4G A;  3TKZ A;  1BG1 A;  2LQN A;  3QWY A;  2Y3A B;  1UUS A;  2YU7 A;  1A1A A;  3PSJ A;  2IUG A;  2JYQ A;  1B47 A;  1RPY A;  1KC2 A;  1BLK A;  2EL8 A;  3GXX A;  2AUG A;  1O4I A;  2MQI A;  4NWG A;  1SHA A;  3OVE A;  1SPS A;  1KA7 A;  5EHR A;  3OV1 A;  1OPK A;  5AXI A;  3ZNI A;  1SHB A;  4K11 A;  2K79 B;  1QG1 E;  3IN7 A;  4LUD A;  2IUI A;  2LNW A;  1Y57 A;  2RMX A;  1O4N A;  1R1Q A;  1O4J A;  2SHP A;  4U1P A;  5GJI A;  3EAC A;  1AYC A;  1O4E A;  4X6S A;  3BUX B;  3MXY A;  3CWG A;  1OO3 A;  5DC4 A;  2MC1 A;  1AOU F;  1AYA A;  1O46 A;  1FHS A;  4XZ0 A;  1JU5 A;  1SHD A;  3CD3 A;  1A07 A;  3C7I A;  5EEQ A;  1A1B A;  1JWO A;  3GQI B;  4A4C A;  1LCK A;  1GRI A;  2EO6 A;  1FBZ A;  1O4A A;  2L6K A;  1AOT F;  3S9K A;  1LUN A;  4DGX A;  2Y1N A;  2FCI A;  1R1P A;  2AOA A;  3TL0 A;  2C0O A;  2EKX A;  2MK2 A;  1A1E A;  5IBM A;  1KA6 A;  1O48 A;  2PLD A;  1D4T A;  1FU6 A;  4H34 A;  1LUK A;  1A08 A;  4NWF A;  3GXW A;  4E93 A;  1BF5 A;  4F5B A;  3BUM B;  4FL2 A;  1X6C A;  3S8L A;  3VRR A;  2H46 E;  2GSB A;  5GJH A;  2MRJ A;  1XA6 A;  3N84 A;  3BUW B;  1F2F A;  2C0I A;  3BKB A;  2OQ1 A;  4P9Z A;  1CSZ A;  4H1O A;  4E68 A;  1HCT B;  1IS0 A;  1IJR A;  2IUH A;  5HKY A;  1O4Q A;  4GWF A;  4GL9 E;  1SKJ A;  2L4K A;  2PNB A;  4FL3 A;  4WWQ A;  1O4O A;  1JYU A;  3MAZ A;  2LCT A;  2Y1M A;  3VS3 A;  3OB2 B;  2EYV A;  1A09 A;  1NZV A;  1CJ1 A;  5EG3 B;  1WQU A;  1BM2 A;  1O43 A;  2OZO A;  4OHH A;  4XZ1 A;  3T04 A;  1O4B A;  3VS2 A;  4QSY A;  2XP1 A;  1BFJ A;  1O49 A;  1JYR A;  3WA4 A;  2CRH A;  1OPL A;  2ABL A;  5I6V A;  2HDX A;  1M61 A;  3N7Y A;  5EEL A;  1TCE A;  3VS7 A;  2DVJ A;  3BUO B;  1M27 A;  2C9W A;  1AYD A;  2L3T A;  2CS0 A;  2H5K A;  2CI8 A;  2HUW A;  3VGO A;  1Z3K A;  1O4D A;  3PFV A;  4K2R A;  2HCK A;  4K45 A;  4EY0 A;  4ROJ A;  1UUR A;  2CI9 A;  3M7F A;  2KK6 A;  1YVL A;  3PSK A;  2LNX A;  3MXC A;  4LUE A;  1LKL A;  1RJA A;  3HIZ B;  4EIH A;  1CSY A;  2EU0 A;  1CWE A;  3UF4 A;  2AOB A;  1FMK A;  4OHI A;  2BBU A;  5EHP A;  3QWX X;  2IZV A;  3S8O A;  3N8M A;  1BFI A;  3CBL A;  3NHN A;  1QAD A;  4L1B B;  2EOB A;  1SPR A;  1KSW A;  3IMD A;  4D8K A;  3PJP A;  2FO0 A;  2RVF A;  3PQZ A;  5AUL A;  1O4P A;  1BHH A;  5KAZ A;  2HDV A;  3CXL A;  1FBV A;  2ECD A;  4U17 A;  4OHD A;  4OHL A;  2DLZ A;  1TZE E; 
#chains in the Genus database with same CATH topology
 2LQW A;  1O4L A;  1AYB A;  1O41 A;  5HKW A;  1CWD L;  3VRZ A;  3VS1 A;  3VS4 A;  5DC9 A;  3PS5 A;  4M4Z A;  1ZFP E;  1BHH B;  3VS6 A;  4JEG A;  2H8H A;  2DX0 A;  1O4K A;  2EO3 A;  1OO4 A;  5DF6 A;  3IMJ A;  1P13 A;  3VRP A;  1PIC A;  1D4W A;  1YVH A;  2GE9 A;  2EYY A;  1K9A A;  3KFJ A;  1I3Z A;  2PLE A;  1O4H A;  1AD5 A;  1LCJ A;  2K7A B;  3IN8 A;  2C0T A;  1G83 A;  2KNO A;  3EAZ A;  1X27 A;  3K2M A;  1MIL A;  5HKZ A;  3HHM B;  4JGH A;  3UYO A;  4DGP A;  1A81 A;  2ETZ A;  1BHF A;  1O42 A;  2DCR A;  1O47 A;  3S8N A;  1O4C A;  2B3O A;  5D0J A;  1NZL A;  1BLJ A;  1GHU A;  1D1Z A;  4JE4 A;  1F1W A;  3VRO A;  1BKM A;  2ROR A;  1R1S A;  3OB1 B;  5J3X A;  1LKK A;  2KGY A;  1O44 A;  2HMH A;  1X0N A;  1MW4 A;  4FBN A;  4P9V A;  1BKL A;  1O45 A;  2DLY A;  3VRQ A;  2PNA A;  3VS5 A;  3PLF B;  3HCK A;  2VIF A;  5DC0 B;  1JYQ A;  1A1C A;  1AB2 A;  4F59 A;  1O4R A;  2PTK A;  3VRY A;  1NRV A;  5CDW A;  3VS0 A;  1HCS B;  3BUN B;  2MRK A;  1Y1U A;  1H9O A;  2DM0 A;  5BO4 A;  2YSX A;  1O4M A;  2CIA A;  2SRC A;  4F5A A;  3US4 A;  4K44 A;  4A4B A;  1LUI A;  3VRN A;  4TZI A;  1LUM A;  1FU5 A;  1QCF A;  5IBS A;  4GPL B;  2RSY A;  4OHE A;  2CR4 A;  1RQQ C;  3OP0 A;  2EYZ A;  1FYR A;  2QMS A;  1BMB A;  2CBL A;  1O4F A;  1O4G A;  3TKZ A;  1BG1 A;  2LQN A;  3QWY A;  2Y3A B;  1UUS A;  2YU7 A;  1A1A A;  3PSJ A;  2IUG A;  2JYQ A;  1B47 A;  1RPY A;  1KC2 A;  1BLK A;  2EL8 A;  3GXX A;  2AUG A;  1O4I A;  3LYV A;  2MQI A;  4NWG A;  1SHA A;  3OVE A;  1SPS A;  1KA7 A;  5EHR A;  3OV1 A;  1OPK A;  5AXI A;  3ZNI A;  1SHB A;  4K11 A;  2K79 B;  1QG1 E;  3IN7 A;  4LUD A;  2IUI A;  2LNW A;  1Y57 A;  2RMX A;  1O4N A;  1R1Q A;  1O4J A;  2SHP A;  4U1P A;  5GJI A;  3EAC A;  1AYC A;  1O4E A;  4X6S A;  3BUX B;  3MXY A;  3CWG A;  1OO3 A;  5DC4 A;  2MC1 A;  1AOU F;  1AYA A;  1O46 A;  1FHS A;  4XZ0 A;  1JU5 A;  1SHD A;  3CD3 A;  1A07 A;  3C7I A;  5EEQ A;  1A1B A;  1JWO A;  3GQI B;  4A4C A;  1LCK A;  1GRI A;  2EO6 A;  1FBZ A;  1O4A A;  2L6K A;  1AOT F;  3S9K A;  1LUN A;  4DGX A;  2Y1N A;  2FCI A;  1R1P A;  2AOA A;  3TL0 A;  2C0O A;  2EKX A;  2MK2 A;  1A1E A;  5IBM A;  1KA6 A;  1O48 A;  2PLD A;  1D4T A;  1FU6 A;  4H34 A;  1LUK A;  1A08 A;  4NWF A;  3GXW A;  4E93 A;  1BF5 A;  4F5B A;  3BUM B;  4FL2 A;  1X6C A;  3S8L A;  3VRR A;  2H46 E;  2GSB A;  5GJH A;  2MRJ A;  1XA6 A;  3N84 A;  3BUW B;  1F2F A;  2C0I A;  3BKB A;  2OQ1 A;  4P9Z A;  1CSZ A;  4H1O A;  4E68 A;  1HCT B;  1IS0 A;  1IJR A;  2IUH A;  5HKY A;  1O4Q A;  4GWF A;  4GL9 E;  1SKJ A;  2L4K A;  2PNB A;  4FL3 A;  4WWQ A;  1O4O A;  1JYU A;  3MAZ A;  2LCT A;  2Y1M A;  3VS3 A;  3OB2 B;  2EYV A;  1A09 A;  1NZV A;  1CJ1 A;  5EG3 B;  1WQU A;  1BM2 A;  1O43 A;  2OZO A;  4OHH A;  4XZ1 A;  3T04 A;  1O4B A;  3VS2 A;  4QSY A;  2XP1 A;  1BFJ A;  1O49 A;  1JYR A;  3K2T A;  3WA4 A;  2CRH A;  1OPL A;  2ABL A;  5I6V A;  2HDX A;  1M61 A;  3N7Y A;  5EEL A;  1TCE A;  3VS7 A;  2DVJ A;  3BUO B;  1M27 A;  2C9W A;  1AYD A;  2L3T A;  2CS0 A;  2H5K A;  2CI8 A;  2HUW A;  3VGO A;  1Z3K A;  1O4D A;  3PFV A;  4K2R A;  2HCK A;  4K45 A;  4EY0 A;  4ROJ A;  1UUR A;  2CI9 A;  3M7F A;  2LRA A;  2KK6 A;  1YVL A;  3PSK A;  2LNX A;  3MXC A;  4LUE A;  1LKL A;  1RJA A;  3HIZ B;  4EIH A;  1CSY A;  2EU0 A;  1CWE A;  3UF4 A;  2AOB A;  1FMK A;  4OHI A;  2BBU A;  5EHP A;  3QWX X;  2IZV A;  3S8O A;  3N8M A;  1BFI A;  3CBL A;  3NHN A;  1QAD A;  4L1B B;  2EOB A;  1SPR A;  1KSW A;  3IMD A;  4D8K A;  3PJP A;  2FO0 A;  2RVF A;  3PQZ A;  5AUL A;  1O4P A;  1BHH A;  5KAZ A;  2HDV A;  3CXL A;  1FBV A;  2ECD A;  4U17 A;  4OHD A;  4OHL A;  2DLZ A;  1TZE E; 
#chains in the Genus database with same CATH homology
 2LQW A;  1O4L A;  1AYB A;  1O41 A;  5HKW A;  1CWD L;  3VRZ A;  3VS1 A;  3VS4 A;  5DC9 A;  3PS5 A;  4M4Z A;  1ZFP E;  1BHH B;  3VS6 A;  4JEG A;  2H8H A;  2DX0 A;  1O4K A;  2EO3 A;  1OO4 A;  5DF6 A;  3IMJ A;  1P13 A;  3VRP A;  1PIC A;  1D4W A;  1YVH A;  2GE9 A;  2EYY A;  1K9A A;  3KFJ A;  1I3Z A;  2PLE A;  1O4H A;  1AD5 A;  1LCJ A;  2K7A B;  3IN8 A;  2C0T A;  1G83 A;  2KNO A;  3EAZ A;  1X27 A;  3K2M A;  1MIL A;  5HKZ A;  3HHM B;  4JGH A;  3UYO A;  4DGP A;  1A81 A;  2ETZ A;  1BHF A;  1O42 A;  2DCR A;  1O47 A;  3S8N A;  1O4C A;  2B3O A;  5D0J A;  1NZL A;  1BLJ A;  1GHU A;  1D1Z A;  4JE4 A;  1F1W A;  3VRO A;  1BKM A;  2ROR A;  1R1S A;  3OB1 B;  5J3X A;  1LKK A;  1O44 A;  2HMH A;  1X0N A;  1MW4 A;  4FBN A;  4P9V A;  1BKL A;  1O45 A;  2DLY A;  3VRQ A;  2PNA A;  3VS5 A;  3PLF B;  3HCK A;  2VIF A;  5DC0 B;  1JYQ A;  1A1C A;  1AB2 A;  4F59 A;  1O4R A;  2PTK A;  3VRY A;  1NRV A;  5CDW A;  3VS0 A;  1HCS B;  3BUN B;  2MRK A;  1Y1U A;  1H9O A;  2DM0 A;  5BO4 A;  2YSX A;  1O4M A;  2CIA A;  2SRC A;  4F5A A;  3US4 A;  4K44 A;  4A4B A;  1LUI A;  3VRN A;  4TZI A;  1LUM A;  1FU5 A;  1QCF A;  5IBS A;  4GPL B;  2RSY A;  4OHE A;  2CR4 A;  1RQQ C;  3OP0 A;  2EYZ A;  1FYR A;  2QMS A;  1BMB A;  2CBL A;  1O4F A;  1O4G A;  3TKZ A;  1BG1 A;  2LQN A;  3QWY A;  2Y3A B;  1UUS A;  2YU7 A;  1A1A A;  3PSJ A;  2IUG A;  2JYQ A;  1B47 A;  1RPY A;  1KC2 A;  1BLK A;  2EL8 A;  3GXX A;  2AUG A;  1O4I A;  2MQI A;  4NWG A;  1SHA A;  3OVE A;  1SPS A;  1KA7 A;  5EHR A;  3OV1 A;  1OPK A;  5AXI A;  3ZNI A;  1SHB A;  4K11 A;  2K79 B;  1QG1 E;  3IN7 A;  4LUD A;  2IUI A;  2LNW A;  1Y57 A;  2RMX A;  1O4N A;  1R1Q A;  1O4J A;  2SHP A;  4U1P A;  5GJI A;  3EAC A;  1AYC A;  1O4E A;  4X6S A;  3BUX B;  3MXY A;  3CWG A;  1OO3 A;  5DC4 A;  2MC1 A;  1AOU F;  1AYA A;  1O46 A;  1FHS A;  4XZ0 A;  1JU5 A;  1SHD A;  3CD3 A;  1A07 A;  3C7I A;  5EEQ A;  1A1B A;  1JWO A;  3GQI B;  4A4C A;  1LCK A;  1GRI A;  2EO6 A;  1FBZ A;  1O4A A;  2L6K A;  1AOT F;  3S9K A;  1LUN A;  4DGX A;  2Y1N A;  2FCI A;  1R1P A;  2AOA A;  3TL0 A;  2C0O A;  2EKX A;  2MK2 A;  1A1E A;  5IBM A;  1KA6 A;  1O48 A;  2PLD A;  1D4T A;  1FU6 A;  4H34 A;  1LUK A;  1A08 A;  4NWF A;  3GXW A;  4E93 A;  1BF5 A;  4F5B A;  3BUM B;  4FL2 A;  1X6C A;  3S8L A;  3VRR A;  2H46 E;  2GSB A;  5GJH A;  2MRJ A;  1XA6 A;  3N84 A;  3BUW B;  1F2F A;  2C0I A;  3BKB A;  2OQ1 A;  4P9Z A;  1CSZ A;  4H1O A;  4E68 A;  1HCT B;  1IS0 A;  1IJR A;  2IUH A;  5HKY A;  1O4Q A;  4GWF A;  4GL9 E;  1SKJ A;  2L4K A;  2PNB A;  4FL3 A;  4WWQ A;  1O4O A;  1JYU A;  3MAZ A;  2LCT A;  2Y1M A;  3VS3 A;  3OB2 B;  2EYV A;  1A09 A;  1NZV A;  1CJ1 A;  5EG3 B;  1WQU A;  1BM2 A;  1O43 A;  2OZO A;  4OHH A;  4XZ1 A;  3T04 A;  1O4B A;  3VS2 A;  4QSY A;  2XP1 A;  1BFJ A;  1O49 A;  1JYR A;  3WA4 A;  2CRH A;  1OPL A;  2ABL A;  5I6V A;  2HDX A;  1M61 A;  3N7Y A;  5EEL A;  1TCE A;  3VS7 A;  2DVJ A;  3BUO B;  1M27 A;  2C9W A;  1AYD A;  2L3T A;  2CS0 A;  2H5K A;  2CI8 A;  2HUW A;  3VGO A;  1Z3K A;  1O4D A;  3PFV A;  4K2R A;  2HCK A;  4K45 A;  4EY0 A;  4ROJ A;  1UUR A;  2CI9 A;  3M7F A;  2KK6 A;  1YVL A;  3PSK A;  2LNX A;  3MXC A;  4LUE A;  1LKL A;  1RJA A;  3HIZ B;  4EIH A;  1CSY A;  2EU0 A;  1CWE A;  3UF4 A;  2AOB A;  1FMK A;  4OHI A;  2BBU A;  5EHP A;  3QWX X;  2IZV A;  3S8O A;  3N8M A;  1BFI A;  3CBL A;  3NHN A;  1QAD A;  4L1B B;  2EOB A;  1SPR A;  1KSW A;  3IMD A;  4D8K A;  3PJP A;  2FO0 A;  2RVF A;  3PQZ A;  5AUL A;  1O4P A;  1BHH A;  5KAZ A;  2HDV A;  3CXL A;  1FBV A;  2ECD A;  4U17 A;  4OHD A;  4OHL A;  2DLZ A;  1TZE E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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