2H46E

Native domain-swapped dimer crystal structure of the grb2 sh2 domain
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
98
structure length
98
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and energetic aspects of Grb2-SH2 domain-swapping.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Growth Receptor Binding Protein 2
total genus 19
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2h46E00
1RQQC 2OQ1A 2H46E 1BHFA 1D1ZA 4OHEA 2JYQA 2MRKA 1NZLA 1QCFA 3OB2B 2CRHA 1SHBA 1FBVA 1KSWA 2KK6A 2CBLA 5EHRA 1FMKA 3OP0A 1BMBA 1LCJA 1SHAA 2RMXA 4FL2A 3UYOA 4L1BB 1FU6A 1AB2A 1AOTF 1D4WA 3S8NA 1TZEE 2DLZA 4WWQA 1OPLA 1A09A 1AYCA 1UUSA 1JU5A 1A81A 1BFJA 2LCTA 4QSYA 2Y1MA 3BKBA 1R1QA 3QWYA 1OO3A 4OHIA 1A08A 3CWGA 1M61A 1BM2A 2FO0A 3HHMB 4FBNA 2XP1A 3VS6A 1O4AA 5EG3B 3VS2A 5IBSA 4D8KA 3HIZB 1SPSA 2VIFA 4XZ0A 1O4QA 1GHUA 2IUGA 2DVJA 1JYUA 2L3TA 1H9OA 3VRYA 2IUIA 2LQWA 1SHDA 2LNWA 4E68A 4U1PA 5GJIA 1SKJA 1LKLA 3PQZA 1O46A 4GPLB 3BUXB 2EOBA 2SHPA 3PJPA 1BLJA 1AYAA 3KFJA 3VRRA 1X0NA 3CXLA 1O4HA 4NWFA 3MXCA 3S9KA 4OHHA 1F1WA 1PICA 3TKZA 2YU7A 1RJAA 1BLKA 5HKYA 1JWOA 3K2MA 1A1BA 1IJRA 2RVFA 5HKZA 5AXIA 2HDVA 2RSYA 1KA7A 4U17A 5BO4A 1CWEA 2EL8A 3GQIB 4K11A 4FL3A 3UF4A 1O4BA 1LUNA 5D0JA 2DX0A 3BUMB 3HCKA 2BBUA 3VRZA 2Y3AB 3PSKA 3IMJA 4A4BA 1O4LA 1LUKA 2C0TA 5EHPA 2CR4A 2HUWA 2L6KA 3VRQA 1KA6A 1XA6A 4H1OA 3OV1A 1Y57A 2EO3A 1B47A 5EELA 2CS0A 1O4OA 3NHNA 1G83A 2LNXA 3US4A 5CDWA 4K45A 1QADA 1AOUF 2HDXA 2QMSA 5AULA 1O4FA 1GRIA 1CSYA 4F5BA 3ZNIA 1M27A 1FYRA 2MK2A 1FHSA 5DC4A 1TCEA 2K7AB 2PLDA 1BKLA 1BF5A 5J3XA 3T04A 2EYVA 5IBMA 1NZVA 4TZIA 1O4KA 1BKMA 2H8HA 1O4CA 3MAZA 1LUIA 2K79B 3VS5A 1O4NA 2PNAA 2GE9A 2DM0A 3VRNA 1CWDL 1O44A 3CD3A 3GXWA 1UURA 4K2RA 3M7FA 4P9VA 3BUOB 2C0OA 2ETZA 3VS1A 1O49A 2IUHA 4H34A 2AOAA 1YVLA 3EACA 3VS4A 1O4PA 1AYDA 1MW4A 4GL9E 2H5KA 4LUDA 2HMHA 4JE4A 1BFIA 3PSJA 3CBLA 1Z3KA 3WA4A 1X6CA 3EAZA 1O42A 1A1EA 3VS3A 1A07A 1KC2A 1WQUA 2EYZA 5DF6A 1D4TA 2MQIA 1O41A 4EIHA 4GWFA 1O47A 3N8MA 3IMDA 3OVEA 2LQNA 2PTKA 4E93A 2KNOA 4NWGA 5KAZA 3PS5A 3GXXA 1MILA 1O4EA 3IN8A 2HCKA 1CSZA 1R1SA 1JYQA 1O4IA 1O4GA 2CIAA 1HCSB 1FU5A 1LCKA 1YVHA 4K44A 1LKKA 1BHHB 1O4RA 2EKXA 2EU0A 4LUEA 1O45A 1O48A 2GSBA 1O4JA 2ABLA 4OHLA 1O4DA 3VGOA 1SPRA 1ZFPE 4F5AA 1AYBA 4A4CA 3QWXX 3N7YA 1R1PA 1A1CA 4P9ZA 1P13A 2C9WA 3VROA 2PNBA 5HKWA 4EY0A 2OZOA 2EO6A 2C0IA 1Y1UA 5EEQA 2DLYA 1I3ZA 1QG1E 1AD5A 3BUWB 1BG1A 3C7IA 4DGPA 2PLEA 1RPYA 4X6SA 5DC9A 5I6VA 4OHDA 2CI8A 2DCRA 4JEGA 3MXYA 2ECDA 2MC1A 2CI9A 2Y1NA 2MRJA 1HCTB 1NRVA 1OO4A 2YSXA 3VS0A 4JGHA 2AOBA 3BUNB 1CJ1A 3VRPA 3N84A 3PLFB 3TL0A 1LUMA 4M4ZA 1F2FA 5DC0B 3PFVA 1O4MA 2AUGA 2B3OA 3VS7A 1OPKA 1IS0A 2RORA 1K9AA 1O43A 2EYYA 3OB1B 1X27A 4ROJA 3IN7A 1JYRA 1FBZA 1A1AA 4XZ1A 3S8LA 1BHHA 2L4KA 4DGXA 3S8OA 2FCIA 5GJHA 2SRCA 2IZVA 4F59A
chains in the Genus database with same CATH superfamily
1RQQC 2OQ1A 2H46E 1BHFA 1D1ZA 4OHEA 2JYQA 2MRKA 1NZLA 1QCFA 3OB2B 2CRHA 2LRAA 1SHBA 1FBVA 1KSWA 2KK6A 2CBLA 5EHRA 1FMKA 3OP0A 1BMBA 1LCJA 1SHAA 2RMXA 4FL2A 3UYOA 2KGYA 4L1BB 1FU6A 1AB2A 1AOTF 1D4WA 3S8NA 1TZEE 2DLZA 4WWQA 1OPLA 1A09A 1AYCA 1UUSA 1JU5A 1A81A 1BFJA 2LCTA 4QSYA 2Y1MA 3BKBA 1R1QA 3QWYA 1OO3A 4OHIA 1A08A 3CWGA 1M61A 1BM2A 2FO0A 3HHMB 4FBNA 2XP1A 3VS6A 1O4AA 5EG3B 3VS2A 5IBSA 4D8KA 3HIZB 1SPSA 2VIFA 4XZ0A 1O4QA 1GHUA 2IUGA 2DVJA 1JYUA 2L3TA 1H9OA 3VRYA 2IUIA 2LQWA 1SHDA 2LNWA 4E68A 4U1PA 5GJIA 1SKJA 1LKLA 3PQZA 1O46A 4GPLB 3BUXB 2EOBA 2SHPA 3PJPA 1BLJA 1AYAA 3KFJA 3VRRA 1X0NA 3CXLA 1O4HA 4NWFA 3MXCA 3S9KA 4OHHA 1F1WA 1PICA 3TKZA 2YU7A 1RJAA 1BLKA 5HKYA 1JWOA 3K2MA 1A1BA 1IJRA 2RVFA 5HKZA 5AXIA 2HDVA 2RSYA 1KA7A 4U17A 5BO4A 1CWEA 2EL8A 3GQIB 4K11A 4FL3A 3UF4A 1O4BA 1LUNA 5D0JA 2DX0A 3BUMB 3HCKA 2BBUA 3VRZA 2Y3AB 3PSKA 3IMJA 4A4BA 1O4LA 1LUKA 2C0TA 5EHPA 2CR4A 2HUWA 2L6KA 3VRQA 1KA6A 1XA6A 4H1OA 3OV1A 1Y57A 2EO3A 1B47A 5EELA 2CS0A 1O4OA 3NHNA 1G83A 2LNXA 3US4A 5CDWA 4K45A 1QADA 1AOUF 2HDXA 2QMSA 5AULA 1O4FA 1GRIA 1CSYA 4F5BA 3ZNIA 1M27A 1FYRA 2MK2A 1FHSA 5DC4A 1TCEA 2K7AB 2PLDA 1BKLA 1BF5A 5J3XA 3T04A 2EYVA 5IBMA 1NZVA 4TZIA 1O4KA 1BKMA 2H8HA 1O4CA 3MAZA 1LUIA 2K79B 3VS5A 1O4NA 2PNAA 3K2TA 2GE9A 2DM0A 3VRNA 1CWDL 1O44A 3CD3A 3GXWA 1UURA 4K2RA 3M7FA 4P9VA 3BUOB 2C0OA 2ETZA 3VS1A 1O49A 2IUHA 4H34A 2AOAA 1YVLA 3EACA 3VS4A 1O4PA 1AYDA 1MW4A 4GL9E 2H5KA 4LUDA 2HMHA 4JE4A 1BFIA 3PSJA 3CBLA 1Z3KA 3WA4A 1X6CA 3EAZA 1O42A 1A1EA 3VS3A 1A07A 1KC2A 1WQUA 2EYZA 5DF6A 1D4TA 2MQIA 1O41A 4EIHA 4GWFA 1O47A 3N8MA 3IMDA 3OVEA 2LQNA 2PTKA 4E93A 2KNOA 4NWGA 5KAZA 3PS5A 3GXXA 1MILA 1O4EA 3IN8A 2HCKA 1CSZA 1R1SA 1JYQA 1O4IA 1O4GA 2CIAA 1HCSB 1FU5A 1LCKA 1YVHA 3LYVA 4K44A 1LKKA 1BHHB 1O4RA 2EKXA 2EU0A 4LUEA 1O45A 1O48A 2GSBA 1O4JA 2ABLA 4OHLA 1O4DA 3VGOA 1SPRA 1ZFPE 4F5AA 1AYBA 4A4CA 3QWXX 3N7YA 1R1PA 1A1CA 4P9ZA 1P13A 2C9WA 3VROA 2PNBA 5HKWA 4EY0A 2OZOA 2EO6A 2C0IA 1Y1UA 5EEQA 2DLYA 1I3ZA 1QG1E 1AD5A 3BUWB 1BG1A 3C7IA 4DGPA 2PLEA 1RPYA 4X6SA 5DC9A 5I6VA 4OHDA 2CI8A 2DCRA 4JEGA 3MXYA 2ECDA 2MC1A 2CI9A 2Y1NA 2MRJA 1HCTB 1NRVA 1OO4A 2YSXA 3VS0A 4JGHA 2AOBA 3BUNB 1CJ1A 3VRPA 3N84A 3PLFB 3TL0A 1LUMA 4M4ZA 1F2FA 5DC0B 3PFVA 1O4MA 2AUGA 2B3OA 3VS7A 1OPKA 1IS0A 2RORA 1K9AA 1O43A 2EYYA 3OB1B 1X27A 4ROJA 3IN7A 1JYRA 1FBZA 1A1AA 4XZ1A 3S8LA 1BHHA 2L4KA 4DGXA 3S8OA 2FCIA 5GJHA 2SRCA 2IZVA 4F59A
chains in the Genus database with same CATH topology
1RQQC 2OQ1A 2H46E 1BHFA 1D1ZA 4OHEA 2JYQA 2MRKA 1NZLA 1QCFA 3OB2B 2CRHA 1SHBA 1FBVA 1KSWA 2KK6A 2CBLA 5EHRA 1FMKA 3OP0A 1BMBA 1LCJA 1SHAA 2RMXA 4FL2A 3UYOA 4L1BB 1FU6A 1AB2A 1AOTF 1D4WA 3S8NA 1TZEE 2DLZA 4WWQA 1OPLA 1A09A 1AYCA 1UUSA 1JU5A 1A81A 1BFJA 2LCTA 4QSYA 2Y1MA 3BKBA 1R1QA 3QWYA 1OO3A 4OHIA 1A08A 3CWGA 1M61A 1BM2A 2FO0A 3HHMB 4FBNA 2XP1A 3VS6A 1O4AA 5EG3B 3VS2A 5IBSA 4D8KA 3HIZB 1SPSA 2VIFA 4XZ0A 1O4QA 1GHUA 2IUGA 2DVJA 1JYUA 2L3TA 1H9OA 3VRYA 2IUIA 2LQWA 1SHDA 2LNWA 4E68A 4U1PA 5GJIA 1SKJA 1LKLA 3PQZA 1O46A 4GPLB 3BUXB 2EOBA 2SHPA 3PJPA 1BLJA 1AYAA 3KFJA 3VRRA 1X0NA 3CXLA 1O4HA 4NWFA 3MXCA 3S9KA 4OHHA 1F1WA 1PICA 3TKZA 2YU7A 1RJAA 1BLKA 5HKYA 1JWOA 3K2MA 1A1BA 1IJRA 2RVFA 5HKZA 5AXIA 2HDVA 2RSYA 1KA7A 4U17A 5BO4A 1CWEA 2EL8A 3GQIB 4K11A 4FL3A 3UF4A 1O4BA 1LUNA 5D0JA 2DX0A 3BUMB 3HCKA 2BBUA 3VRZA 2Y3AB 3PSKA 3IMJA 4A4BA 1O4LA 1LUKA 2C0TA 5EHPA 2CR4A 2HUWA 2L6KA 3VRQA 1KA6A 1XA6A 4H1OA 3OV1A 1Y57A 2EO3A 1B47A 5EELA 2CS0A 1O4OA 3NHNA 1G83A 2LNXA 3US4A 5CDWA 4K45A 1QADA 1AOUF 2HDXA 2QMSA 5AULA 1O4FA 1GRIA 1CSYA 4F5BA 3ZNIA 1M27A 1FYRA 2MK2A 1FHSA 5DC4A 1TCEA 2K7AB 2PLDA 1BKLA 1BF5A 5J3XA 3T04A 2EYVA 5IBMA 1NZVA 4TZIA 1O4KA 1BKMA 2H8HA 1O4CA 3MAZA 1LUIA 2K79B 3VS5A 1O4NA 2PNAA 2GE9A 2DM0A 3VRNA 1CWDL 1O44A 3CD3A 3GXWA 1UURA 4K2RA 3M7FA 4P9VA 3BUOB 2C0OA 2ETZA 3VS1A 1O49A 2IUHA 4H34A 2AOAA 1YVLA 3EACA 3VS4A 1O4PA 1AYDA 1MW4A 4GL9E 2H5KA 4LUDA 2HMHA 4JE4A 1BFIA 3PSJA 3CBLA 1Z3KA 3WA4A 1X6CA 3EAZA 1O42A 1A1EA 3VS3A 1A07A 1KC2A 1WQUA 2EYZA 5DF6A 1D4TA 2MQIA 1O41A 4EIHA 4GWFA 1O47A 3N8MA 3IMDA 3OVEA 2LQNA 2PTKA 4E93A 2KNOA 4NWGA 5KAZA 3PS5A 3GXXA 1MILA 1O4EA 3IN8A 2HCKA 1CSZA 1R1SA 1JYQA 1O4IA 1O4GA 2CIAA 1HCSB 1FU5A 1LCKA 1YVHA 4K44A 1LKKA 1BHHB 1O4RA 2EKXA 2EU0A 4LUEA 1O45A 1O48A 2GSBA 1O4JA 2ABLA 4OHLA 1O4DA 3VGOA 1SPRA 1ZFPE 4F5AA 1AYBA 4A4CA 3QWXX 3N7YA 1R1PA 1A1CA 4P9ZA 1P13A 2C9WA 3VROA 2PNBA 5HKWA 4EY0A 2OZOA 2EO6A 2C0IA 1Y1UA 5EEQA 2DLYA 1I3ZA 1QG1E 1AD5A 3BUWB 1BG1A 3C7IA 4DGPA 2PLEA 1RPYA 4X6SA 5DC9A 5I6VA 4OHDA 2CI8A 2DCRA 4JEGA 3MXYA 2ECDA 2MC1A 2CI9A 2Y1NA 2MRJA 1HCTB 1NRVA 1OO4A 2YSXA 3VS0A 4JGHA 2AOBA 3BUNB 1CJ1A 3VRPA 3N84A 3PLFB 3TL0A 1LUMA 4M4ZA 1F2FA 5DC0B 3PFVA 1O4MA 2AUGA 2B3OA 3VS7A 1OPKA 1IS0A 2RORA 1K9AA 1O43A 2EYYA 3OB1B 1X27A 4ROJA 3IN7A 1JYRA 1FBZA 1A1AA 4XZ1A 3S8LA 1BHHA 2L4KA 4DGXA 3S8OA 2FCIA 5GJHA 2SRCA 2IZVA 4F59A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RQQ C;  2OQ1 A;  2H46 E;  1BHF A;  1D1Z A;  4OHE A;  2JYQ A;  2MRK A;  1NZL A;  1QCF A;  3OB2 B;  2CRH A;  1SHB A;  1FBV A;  1KSW A;  2KK6 A;  2CBL A;  5EHR A;  1FMK A;  3OP0 A;  1BMB A;  1LCJ A;  1SHA A;  2RMX A;  4FL2 A;  3UYO A;  4L1B B;  1FU6 A;  1AB2 A;  1AOT F;  1D4W A;  3S8N A;  1TZE E;  2DLZ A;  4WWQ A;  1OPL A;  1A09 A;  1AYC A;  1UUS A;  1JU5 A;  1A81 A;  1BFJ A;  2LCT A;  4QSY A;  2Y1M A;  3BKB A;  1R1Q A;  3QWY A;  1OO3 A;  4OHI A;  1A08 A;  3CWG A;  1M61 A;  1BM2 A;  2FO0 A;  3HHM B;  4FBN A;  2XP1 A;  3VS6 A;  1O4A A;  5EG3 B;  3VS2 A;  5IBS A;  4D8K A;  3HIZ B;  1SPS A;  2VIF A;  4XZ0 A;  1O4Q A;  1GHU A;  2IUG A;  2DVJ A;  1JYU A;  2L3T A;  1H9O A;  3VRY A;  2IUI A;  2LQW A;  1SHD A;  2LNW A;  4E68 A;  4U1P A;  5GJI A;  1SKJ A;  1LKL A;  3PQZ A;  1O46 A;  4GPL B;  3BUX B;  2EOB A;  2SHP A;  3PJP A;  1BLJ A;  1AYA A;  3KFJ A;  3VRR A;  1X0N A;  3CXL A;  1O4H A;  4NWF A;  3MXC A;  3S9K A;  4OHH A;  1F1W A;  1PIC A;  3TKZ A;  2YU7 A;  1RJA A;  1BLK A;  5HKY A;  1JWO A;  3K2M A;  1A1B A;  1IJR A;  2RVF A;  5HKZ A;  5AXI A;  2HDV A;  2RSY A;  1KA7 A;  4U17 A;  5BO4 A;  1CWE A;  2EL8 A;  3GQI B;  4K11 A;  4FL3 A;  3UF4 A;  1O4B A;  1LUN A;  5D0J A;  2DX0 A;  3BUM B;  3HCK A;  2BBU A;  3VRZ A;  2Y3A B;  3PSK A;  3IMJ A;  4A4B A;  1O4L A;  1LUK A;  2C0T A;  5EHP A;  2CR4 A;  2HUW A;  2L6K A;  3VRQ A;  1KA6 A;  1XA6 A;  4H1O A;  3OV1 A;  1Y57 A;  2EO3 A;  1B47 A;  5EEL A;  2CS0 A;  1O4O A;  3NHN A;  1G83 A;  2LNX A;  3US4 A;  5CDW A;  4K45 A;  1QAD A;  1AOU F;  2HDX A;  2QMS A;  5AUL A;  1O4F A;  1GRI A;  1CSY A;  4F5B A;  3ZNI A;  1M27 A;  1FYR A;  2MK2 A;  1FHS A;  5DC4 A;  1TCE A;  2K7A B;  2PLD A;  1BKL A;  1BF5 A;  5J3X A;  3T04 A;  2EYV A;  5IBM A;  1NZV A;  4TZI A;  1O4K A;  1BKM A;  2H8H A;  1O4C A;  3MAZ A;  1LUI A;  2K79 B;  3VS5 A;  1O4N A;  2PNA A;  2GE9 A;  2DM0 A;  3VRN A;  1CWD L;  1O44 A;  3CD3 A;  3GXW A;  1UUR A;  4K2R A;  3M7F A;  4P9V A;  3BUO B;  2C0O A;  2ETZ A;  3VS1 A;  1O49 A;  2IUH A;  4H34 A;  2AOA A;  1YVL A;  3EAC A;  3VS4 A;  1O4P A;  1AYD A;  1MW4 A;  4GL9 E;  2H5K A;  4LUD A;  2HMH A;  4JE4 A;  1BFI A;  3PSJ A;  3CBL A;  1Z3K A;  3WA4 A;  1X6C A;  3EAZ A;  1O42 A;  1A1E A;  3VS3 A;  1A07 A;  1KC2 A;  1WQU A;  2EYZ A;  5DF6 A;  1D4T A;  2MQI A;  1O41 A;  4EIH A;  4GWF A;  1O47 A;  3N8M A;  3IMD A;  3OVE A;  2LQN A;  2PTK A;  4E93 A;  2KNO A;  4NWG A;  5KAZ A;  3PS5 A;  3GXX A;  1MIL A;  1O4E A;  3IN8 A;  2HCK A;  1CSZ A;  1R1S A;  1JYQ A;  1O4I A;  1O4G A;  2CIA A;  1HCS B;  1FU5 A;  1LCK A;  1YVH A;  4K44 A;  1LKK A;  1BHH B;  1O4R A;  2EKX A;  2EU0 A;  4LUE A;  1O45 A;  1O48 A;  2GSB A;  1O4J A;  2ABL A;  4OHL A;  1O4D A;  3VGO A;  1SPR A;  1ZFP E;  4F5A A;  1AYB A;  4A4C A;  3QWX X;  3N7Y A;  1R1P A;  1A1C A;  4P9Z A;  1P13 A;  2C9W A;  3VRO A;  2PNB A;  5HKW A;  4EY0 A;  2OZO A;  2EO6 A;  2C0I A;  1Y1U A;  5EEQ A;  2DLY A;  1I3Z A;  1QG1 E;  1AD5 A;  3BUW B;  1BG1 A;  3C7I A;  4DGP A;  2PLE A;  1RPY A;  4X6S A;  5DC9 A;  5I6V A;  4OHD A;  2CI8 A;  2DCR A;  4JEG A;  3MXY A;  2ECD A;  2MC1 A;  2CI9 A;  2Y1N A;  2MRJ A;  1HCT B;  1NRV A;  1OO4 A;  2YSX A;  3VS0 A;  4JGH A;  2AOB A;  3BUN B;  1CJ1 A;  3VRP A;  3N84 A;  3PLF B;  3TL0 A;  1LUM A;  4M4Z A;  1F2F A;  5DC0 B;  3PFV A;  1O4M A;  2AUG A;  2B3O A;  3VS7 A;  1OPK A;  1IS0 A;  2ROR A;  1K9A A;  1O43 A;  2EYY A;  3OB1 B;  1X27 A;  4ROJ A;  3IN7 A;  1JYR A;  1FBZ A;  1A1A A;  4XZ1 A;  3S8L A;  1BHH A;  2L4K A;  4DGX A;  3S8O A;  2FCI A;  5GJH A;  2SRC A;  2IZV A;  4F59 A; 
#chains in the Genus database with same CATH topology
 1RQQ C;  2OQ1 A;  2H46 E;  1BHF A;  1D1Z A;  4OHE A;  2JYQ A;  2MRK A;  1NZL A;  1QCF A;  3OB2 B;  2CRH A;  2LRA A;  1SHB A;  1FBV A;  1KSW A;  2KK6 A;  2CBL A;  5EHR A;  1FMK A;  3OP0 A;  1BMB A;  1LCJ A;  1SHA A;  2RMX A;  4FL2 A;  3UYO A;  2KGY A;  4L1B B;  1FU6 A;  1AB2 A;  1AOT F;  1D4W A;  3S8N A;  1TZE E;  2DLZ A;  4WWQ A;  1OPL A;  1A09 A;  1AYC A;  1UUS A;  1JU5 A;  1A81 A;  1BFJ A;  2LCT A;  4QSY A;  2Y1M A;  3BKB A;  1R1Q A;  3QWY A;  1OO3 A;  4OHI A;  1A08 A;  3CWG A;  1M61 A;  1BM2 A;  2FO0 A;  3HHM B;  4FBN A;  2XP1 A;  3VS6 A;  1O4A A;  5EG3 B;  3VS2 A;  5IBS A;  4D8K A;  3HIZ B;  1SPS A;  2VIF A;  4XZ0 A;  1O4Q A;  1GHU A;  2IUG A;  2DVJ A;  1JYU A;  2L3T A;  1H9O A;  3VRY A;  2IUI A;  2LQW A;  1SHD A;  2LNW A;  4E68 A;  4U1P A;  5GJI A;  1SKJ A;  1LKL A;  3PQZ A;  1O46 A;  4GPL B;  3BUX B;  2EOB A;  2SHP A;  3PJP A;  1BLJ A;  1AYA A;  3KFJ A;  3VRR A;  1X0N A;  3CXL A;  1O4H A;  4NWF A;  3MXC A;  3S9K A;  4OHH A;  1F1W A;  1PIC A;  3TKZ A;  2YU7 A;  1RJA A;  1BLK A;  5HKY A;  1JWO A;  3K2M A;  1A1B A;  1IJR A;  2RVF A;  5HKZ A;  5AXI A;  2HDV A;  2RSY A;  1KA7 A;  4U17 A;  5BO4 A;  1CWE A;  2EL8 A;  3GQI B;  4K11 A;  4FL3 A;  3UF4 A;  1O4B A;  1LUN A;  5D0J A;  2DX0 A;  3BUM B;  3HCK A;  2BBU A;  3VRZ A;  2Y3A B;  3PSK A;  3IMJ A;  4A4B A;  1O4L A;  1LUK A;  2C0T A;  5EHP A;  2CR4 A;  2HUW A;  2L6K A;  3VRQ A;  1KA6 A;  1XA6 A;  4H1O A;  3OV1 A;  1Y57 A;  2EO3 A;  1B47 A;  5EEL A;  2CS0 A;  1O4O A;  3NHN A;  1G83 A;  2LNX A;  3US4 A;  5CDW A;  4K45 A;  1QAD A;  1AOU F;  2HDX A;  2QMS A;  5AUL A;  1O4F A;  1GRI A;  1CSY A;  4F5B A;  3ZNI A;  1M27 A;  1FYR A;  2MK2 A;  1FHS A;  5DC4 A;  1TCE A;  2K7A B;  2PLD A;  1BKL A;  1BF5 A;  5J3X A;  3T04 A;  2EYV A;  5IBM A;  1NZV A;  4TZI A;  1O4K A;  1BKM A;  2H8H A;  1O4C A;  3MAZ A;  1LUI A;  2K79 B;  3VS5 A;  1O4N A;  2PNA A;  3K2T A;  2GE9 A;  2DM0 A;  3VRN A;  1CWD L;  1O44 A;  3CD3 A;  3GXW A;  1UUR A;  4K2R A;  3M7F A;  4P9V A;  3BUO B;  2C0O A;  2ETZ A;  3VS1 A;  1O49 A;  2IUH A;  4H34 A;  2AOA A;  1YVL A;  3EAC A;  3VS4 A;  1O4P A;  1AYD A;  1MW4 A;  4GL9 E;  2H5K A;  4LUD A;  2HMH A;  4JE4 A;  1BFI A;  3PSJ A;  3CBL A;  1Z3K A;  3WA4 A;  1X6C A;  3EAZ A;  1O42 A;  1A1E A;  3VS3 A;  1A07 A;  1KC2 A;  1WQU A;  2EYZ A;  5DF6 A;  1D4T A;  2MQI A;  1O41 A;  4EIH A;  4GWF A;  1O47 A;  3N8M A;  3IMD A;  3OVE A;  2LQN A;  2PTK A;  4E93 A;  2KNO A;  4NWG A;  5KAZ A;  3PS5 A;  3GXX A;  1MIL A;  1O4E A;  3IN8 A;  2HCK A;  1CSZ A;  1R1S A;  1JYQ A;  1O4I A;  1O4G A;  2CIA A;  1HCS B;  1FU5 A;  1LCK A;  1YVH A;  3LYV A;  4K44 A;  1LKK A;  1BHH B;  1O4R A;  2EKX A;  2EU0 A;  4LUE A;  1O45 A;  1O48 A;  2GSB A;  1O4J A;  2ABL A;  4OHL A;  1O4D A;  3VGO A;  1SPR A;  1ZFP E;  4F5A A;  1AYB A;  4A4C A;  3QWX X;  3N7Y A;  1R1P A;  1A1C A;  4P9Z A;  1P13 A;  2C9W A;  3VRO A;  2PNB A;  5HKW A;  4EY0 A;  2OZO A;  2EO6 A;  2C0I A;  1Y1U A;  5EEQ A;  2DLY A;  1I3Z A;  1QG1 E;  1AD5 A;  3BUW B;  1BG1 A;  3C7I A;  4DGP A;  2PLE A;  1RPY A;  4X6S A;  5DC9 A;  5I6V A;  4OHD A;  2CI8 A;  2DCR A;  4JEG A;  3MXY A;  2ECD A;  2MC1 A;  2CI9 A;  2Y1N A;  2MRJ A;  1HCT B;  1NRV A;  1OO4 A;  2YSX A;  3VS0 A;  4JGH A;  2AOB A;  3BUN B;  1CJ1 A;  3VRP A;  3N84 A;  3PLF B;  3TL0 A;  1LUM A;  4M4Z A;  1F2F A;  5DC0 B;  3PFV A;  1O4M A;  2AUG A;  2B3O A;  3VS7 A;  1OPK A;  1IS0 A;  2ROR A;  1K9A A;  1O43 A;  2EYY A;  3OB1 B;  1X27 A;  4ROJ A;  3IN7 A;  1JYR A;  1FBZ A;  1A1A A;  4XZ1 A;  3S8L A;  1BHH A;  2L4K A;  4DGX A;  3S8O A;  2FCI A;  5GJH A;  2SRC A;  2IZV A;  4F59 A; 
#chains in the Genus database with same CATH homology
 1RQQ C;  2OQ1 A;  2H46 E;  1BHF A;  1D1Z A;  4OHE A;  2JYQ A;  2MRK A;  1NZL A;  1QCF A;  3OB2 B;  2CRH A;  1SHB A;  1FBV A;  1KSW A;  2KK6 A;  2CBL A;  5EHR A;  1FMK A;  3OP0 A;  1BMB A;  1LCJ A;  1SHA A;  2RMX A;  4FL2 A;  3UYO A;  4L1B B;  1FU6 A;  1AB2 A;  1AOT F;  1D4W A;  3S8N A;  1TZE E;  2DLZ A;  4WWQ A;  1OPL A;  1A09 A;  1AYC A;  1UUS A;  1JU5 A;  1A81 A;  1BFJ A;  2LCT A;  4QSY A;  2Y1M A;  3BKB A;  1R1Q A;  3QWY A;  1OO3 A;  4OHI A;  1A08 A;  3CWG A;  1M61 A;  1BM2 A;  2FO0 A;  3HHM B;  4FBN A;  2XP1 A;  3VS6 A;  1O4A A;  5EG3 B;  3VS2 A;  5IBS A;  4D8K A;  3HIZ B;  1SPS A;  2VIF A;  4XZ0 A;  1O4Q A;  1GHU A;  2IUG A;  2DVJ A;  1JYU A;  2L3T A;  1H9O A;  3VRY A;  2IUI A;  2LQW A;  1SHD A;  2LNW A;  4E68 A;  4U1P A;  5GJI A;  1SKJ A;  1LKL A;  3PQZ A;  1O46 A;  4GPL B;  3BUX B;  2EOB A;  2SHP A;  3PJP A;  1BLJ A;  1AYA A;  3KFJ A;  3VRR A;  1X0N A;  3CXL A;  1O4H A;  4NWF A;  3MXC A;  3S9K A;  4OHH A;  1F1W A;  1PIC A;  3TKZ A;  2YU7 A;  1RJA A;  1BLK A;  5HKY A;  1JWO A;  3K2M A;  1A1B A;  1IJR A;  2RVF A;  5HKZ A;  5AXI A;  2HDV A;  2RSY A;  1KA7 A;  4U17 A;  5BO4 A;  1CWE A;  2EL8 A;  3GQI B;  4K11 A;  4FL3 A;  3UF4 A;  1O4B A;  1LUN A;  5D0J A;  2DX0 A;  3BUM B;  3HCK A;  2BBU A;  3VRZ A;  2Y3A B;  3PSK A;  3IMJ A;  4A4B A;  1O4L A;  1LUK A;  2C0T A;  5EHP A;  2CR4 A;  2HUW A;  2L6K A;  3VRQ A;  1KA6 A;  1XA6 A;  4H1O A;  3OV1 A;  1Y57 A;  2EO3 A;  1B47 A;  5EEL A;  2CS0 A;  1O4O A;  3NHN A;  1G83 A;  2LNX A;  3US4 A;  5CDW A;  4K45 A;  1QAD A;  1AOU F;  2HDX A;  2QMS A;  5AUL A;  1O4F A;  1GRI A;  1CSY A;  4F5B A;  3ZNI A;  1M27 A;  1FYR A;  2MK2 A;  1FHS A;  5DC4 A;  1TCE A;  2K7A B;  2PLD A;  1BKL A;  1BF5 A;  5J3X A;  3T04 A;  2EYV A;  5IBM A;  1NZV A;  4TZI A;  1O4K A;  1BKM A;  2H8H A;  1O4C A;  3MAZ A;  1LUI A;  2K79 B;  3VS5 A;  1O4N A;  2PNA A;  2GE9 A;  2DM0 A;  3VRN A;  1CWD L;  1O44 A;  3CD3 A;  3GXW A;  1UUR A;  4K2R A;  3M7F A;  4P9V A;  3BUO B;  2C0O A;  2ETZ A;  3VS1 A;  1O49 A;  2IUH A;  4H34 A;  2AOA A;  1YVL A;  3EAC A;  3VS4 A;  1O4P A;  1AYD A;  1MW4 A;  4GL9 E;  2H5K A;  4LUD A;  2HMH A;  4JE4 A;  1BFI A;  3PSJ A;  3CBL A;  1Z3K A;  3WA4 A;  1X6C A;  3EAZ A;  1O42 A;  1A1E A;  3VS3 A;  1A07 A;  1KC2 A;  1WQU A;  2EYZ A;  5DF6 A;  1D4T A;  2MQI A;  1O41 A;  4EIH A;  4GWF A;  1O47 A;  3N8M A;  3IMD A;  3OVE A;  2LQN A;  2PTK A;  4E93 A;  2KNO A;  4NWG A;  5KAZ A;  3PS5 A;  3GXX A;  1MIL A;  1O4E A;  3IN8 A;  2HCK A;  1CSZ A;  1R1S A;  1JYQ A;  1O4I A;  1O4G A;  2CIA A;  1HCS B;  1FU5 A;  1LCK A;  1YVH A;  4K44 A;  1LKK A;  1BHH B;  1O4R A;  2EKX A;  2EU0 A;  4LUE A;  1O45 A;  1O48 A;  2GSB A;  1O4J A;  2ABL A;  4OHL A;  1O4D A;  3VGO A;  1SPR A;  1ZFP E;  4F5A A;  1AYB A;  4A4C A;  3QWX X;  3N7Y A;  1R1P A;  1A1C A;  4P9Z A;  1P13 A;  2C9W A;  3VRO A;  2PNB A;  5HKW A;  4EY0 A;  2OZO A;  2EO6 A;  2C0I A;  1Y1U A;  5EEQ A;  2DLY A;  1I3Z A;  1QG1 E;  1AD5 A;  3BUW B;  1BG1 A;  3C7I A;  4DGP A;  2PLE A;  1RPY A;  4X6S A;  5DC9 A;  5I6V A;  4OHD A;  2CI8 A;  2DCR A;  4JEG A;  3MXY A;  2ECD A;  2MC1 A;  2CI9 A;  2Y1N A;  2MRJ A;  1HCT B;  1NRV A;  1OO4 A;  2YSX A;  3VS0 A;  4JGH A;  2AOB A;  3BUN B;  1CJ1 A;  3VRP A;  3N84 A;  3PLF B;  3TL0 A;  1LUM A;  4M4Z A;  1F2F A;  5DC0 B;  3PFV A;  1O4M A;  2AUG A;  2B3O A;  3VS7 A;  1OPK A;  1IS0 A;  2ROR A;  1K9A A;  1O43 A;  2EYY A;  3OB1 B;  1X27 A;  4ROJ A;  3IN7 A;  1JYR A;  1FBZ A;  1A1A A;  4XZ1 A;  3S8L A;  1BHH A;  2L4K A;  4DGX A;  3S8O A;  2FCI A;  5GJH A;  2SRC A;  2IZV A;  4F59 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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