2IUGA

Crystal structure of the pi3-kinase p85 n-terminal sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
110
structure length
110
Chain Sequence
NNMSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
total genus 29
structure length 110
sequence length 110
ec nomenclature
pdb deposition date 2006-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2iugA00
3VRYA 1BFIA 3UYOA 3S9KA 3QWXX 3PQZA 1NZVA 2CRHA 3IMDA 2AOBA 3MXCA 1WQUA 1LUKA 1A1CA 3VRPA 3OB2B 3PJPA 4GL9E 1BM2A 1O4OA 1O4MA 1O49A 1SPRA 1CJ1A 1FU5A 1O4BA 1O4LA 3MXYA 1O4IA 1SHAA 3VS5A 2H5KA 1YVHA 2RORA 1O4FA 1GRIA 1BMBA 4XZ1A 1SPSA 1CSYA 3PSJA 1D4WA 2HUWA 4FL3A 3PFVA 5GJIA 1O4EA 1O4CA 2MK2A 5AULA 3BUOB 3EACA 3VS6A 2L4KA 4P9ZA 4OHLA 4A4CA 1LKKA 2DCRA 1FU6A 3CBLA 1BFJA 3CXLA 5DC9A 2RSYA 1O4JA 1BKLA 1UUSA 1FHSA 4OHDA 1NZLA 2MRJA 3HIZB 2EKXA 3US4A 2YU7A 4OHHA 1O4NA 1PICA 3VS2A 2CIAA 4LUDA 3BUNB 1TCEA 1AOUF 4E93A 3BKBA 2LQWA 1AOTF 2L3TA 3QWYA 1AYAA 1BHHB 2HDXA 5HKWA 2KK6A 1FBVA 4M4ZA 5EHPA 1SKJA 2EO3A 1RPYA 3NHNA 3WA4A 5CDWA 1BHFA 4U17A 4D8KA 1Y57A 1JU5A 4EIHA 2H46E 3VRNA 2FO0A 1GHUA 1KSWA 1O47A 4ROJA 1IS0A 1JYUA 2CI8A 3N7YA 1G83A 1FYRA 1NRVA 1R1SA 4JEGA 4WWQA 1H9OA 3UF4A 3OP0A 5DF6A 1Y1UA 2ABLA 2C0IA 3M7FA 1BLKA 2B3OA 1CWEA 2K79B 1KA6A 1LCJA 4P9VA 1O46A 1QCFA 1TZEE 2ECDA 4E68A 1RJAA 4K44A 2Y3AB 1JYRA 4EY0A 5AXIA 4X6SA 5EELA 2LNWA 3K2MA 1R1QA 4JGHA 1O45A 4XZ0A 2GE9A 2AUGA 4K2RA 1O4RA 5HKYA 3BUMB 1X6CA 1B47A 3TL0A 2DM0A 3CD3A 2K7AB 1JYQA 1OO3A 1A81A 5J3XA 1AD5A 5I6VA 2VIFA 4FBNA 2AOAA 1M61A 3KFJA 2YSXA 5EEQA 2MC1A 2PNBA 3TKZA 1CWDL 3VS7A 2C9WA 3MAZA 1LCKA 1O4KA 4OHIA 1BHHA 3GQIB 3PLFB 2RVFA 2SHPA 1BF5A 1O4QA 3VS1A 1O48A 2CS0A 1O42A 3VROA 2LCTA 5HKZA 1OPLA 1RQQC 5IBSA 1AYBA 4U1PA 1KC2A 2C0TA 2CR4A 4LUEA 2GSBA 2HCKA 3VGOA 3VS3A 1X0NA 3VRRA 1A08A 4F59A 1KA7A 1SHBA 3HCKA 2RMXA 4A4BA 1O41A 4TZIA 1BKMA 1P13A 1R1PA 5D0JA 2EL8A 2HDVA 3PS5A 2FCIA 1BG1A 5DC4A 5EG3B 3N84A 1M27A 2DVJA 2EYVA 2DLZA 1X27A 3S8NA 3BUXB 1I3ZA 2PNAA 3VRZA 2EYZA 1ZFPE 1A1EA 3S8OA 1YVLA 2IZVA 4NWGA 3OVEA 1F1WA 2LQNA 2BBUA 4NWFA 2PLDA 2C0OA 1MILA 2CBLA 1A07A 1JWOA 2EOBA 3VS4A 3IN8A 2QMSA 2OQ1A 1XA6A 4F5AA 2KNOA 2IUIA 3VS0A 3S8LA 1AYCA 1O4GA 5BO4A 2EO6A 4FL2A 3VRQA 3OV1A 3OB1B 2EYYA 2SRCA 1OO4A 1O4PA 1D4TA 2Y1MA 4K45A 3BUWB 4OHEA 3IMJA 1Z3KA 4QSYA 3PSKA 2L6KA 1HCTB 3C7IA 2CI9A 2LNXA 1O4AA 1FMKA 2EU0A 1F2FA 3EAZA 2IUGA 3HHMB 1FBZA 4GPLB 3ZNIA 1AB2A 5DC0B 4DGPA 4L1BB 1LUMA 1A09A 1O4DA 1O43A 2IUHA 3CWGA 1LUNA 2OZOA 3T04A 4JE4A 2MQIA 2ETZA 2HMHA 2XP1A 3GXXA 1A1AA 3IN7A 4F5BA 1UURA 5KAZA 2PLEA 3N8MA 2MRKA 5IBMA 3GXWA 4H34A 2JYQA 1OPKA 4K11A 1HCSB 2Y1NA 1D1ZA 1CSZA 1QG1E 2DX0A 4GWFA 1O4HA 5EHRA 1IJRA 2PTKA 1A1BA 2DLYA 4DGXA 1LKLA 1SHDA 1K9AA 1MW4A 1O44A 1AYDA 5GJHA 1QADA 1LUIA 2H8HA 1BLJA 4H1OA
chains in the Genus database with same CATH superfamily
3VRYA 1BFIA 3UYOA 3S9KA 3QWXX 3PQZA 1NZVA 2CRHA 3IMDA 2AOBA 3MXCA 1WQUA 1LUKA 1A1CA 3VRPA 3OB2B 3PJPA 4GL9E 1BM2A 1O4OA 1O4MA 1O49A 1SPRA 1CJ1A 1FU5A 1O4BA 1O4LA 3MXYA 1O4IA 1SHAA 2LRAA 3VS5A 2H5KA 1YVHA 2RORA 1O4FA 1GRIA 1BMBA 4XZ1A 1SPSA 1CSYA 3PSJA 1D4WA 2HUWA 4FL3A 3PFVA 5GJIA 1O4EA 1O4CA 2MK2A 5AULA 3BUOB 3EACA 3VS6A 2L4KA 4P9ZA 4OHLA 4A4CA 1LKKA 2DCRA 1FU6A 3CBLA 1BFJA 3CXLA 5DC9A 2RSYA 1O4JA 1BKLA 1UUSA 1FHSA 4OHDA 1NZLA 2MRJA 3HIZB 2EKXA 3US4A 2YU7A 4OHHA 1O4NA 1PICA 3VS2A 2CIAA 4LUDA 3BUNB 1TCEA 1AOUF 4E93A 3BKBA 2LQWA 1AOTF 2L3TA 3QWYA 1AYAA 1BHHB 2HDXA 5HKWA 2KK6A 1FBVA 4M4ZA 5EHPA 1SKJA 2EO3A 1RPYA 3NHNA 3WA4A 5CDWA 1BHFA 4U17A 4D8KA 1Y57A 1JU5A 4EIHA 2H46E 3VRNA 2FO0A 1GHUA 1KSWA 1O47A 4ROJA 1IS0A 1JYUA 2CI8A 3N7YA 1G83A 1FYRA 1NRVA 1R1SA 4JEGA 3LYVA 4WWQA 1H9OA 3UF4A 3OP0A 5DF6A 1Y1UA 2ABLA 2C0IA 3M7FA 1BLKA 2B3OA 1CWEA 2K79B 1KA6A 1LCJA 4P9VA 1O46A 1QCFA 1TZEE 2ECDA 4E68A 1RJAA 4K44A 2Y3AB 1JYRA 4EY0A 5AXIA 4X6SA 5EELA 2LNWA 3K2MA 1R1QA 4JGHA 1O45A 4XZ0A 2GE9A 2AUGA 4K2RA 1O4RA 5HKYA 3BUMB 1X6CA 1B47A 3TL0A 2DM0A 3CD3A 2K7AB 1JYQA 1OO3A 1A81A 5J3XA 1AD5A 5I6VA 2VIFA 4FBNA 2AOAA 1M61A 3KFJA 2YSXA 5EEQA 2MC1A 2PNBA 3TKZA 1CWDL 3VS7A 2C9WA 3MAZA 1LCKA 1O4KA 4OHIA 1BHHA 3GQIB 3PLFB 2RVFA 2SHPA 1BF5A 1O4QA 3VS1A 1O48A 2CS0A 1O42A 3VROA 2LCTA 5HKZA 1OPLA 1RQQC 5IBSA 1AYBA 4U1PA 1KC2A 2C0TA 2CR4A 4LUEA 2GSBA 2HCKA 3VGOA 3VS3A 1X0NA 3VRRA 1A08A 4F59A 1KA7A 1SHBA 3HCKA 2RMXA 4A4BA 1O41A 4TZIA 1BKMA 1P13A 1R1PA 5D0JA 2EL8A 2HDVA 3PS5A 2FCIA 1BG1A 3K2TA 5DC4A 5EG3B 3N84A 1M27A 2DVJA 2EYVA 2DLZA 1X27A 3S8NA 3BUXB 1I3ZA 2PNAA 3VRZA 2EYZA 1ZFPE 1A1EA 3S8OA 1YVLA 2IZVA 4NWGA 3OVEA 1F1WA 2LQNA 2BBUA 4NWFA 2PLDA 2C0OA 1MILA 2CBLA 1A07A 1JWOA 2EOBA 3VS4A 3IN8A 2QMSA 2OQ1A 1XA6A 4F5AA 2KNOA 2IUIA 3VS0A 3S8LA 1AYCA 1O4GA 5BO4A 2EO6A 4FL2A 3VRQA 3OV1A 3OB1B 2EYYA 2SRCA 1OO4A 1O4PA 1D4TA 2Y1MA 4K45A 3BUWB 4OHEA 3IMJA 1Z3KA 4QSYA 3PSKA 2L6KA 1HCTB 3C7IA 2CI9A 2LNXA 1O4AA 1FMKA 2EU0A 1F2FA 3EAZA 2IUGA 3HHMB 1FBZA 4GPLB 3ZNIA 1AB2A 5DC0B 4DGPA 4L1BB 1LUMA 1A09A 1O4DA 1O43A 2IUHA 3CWGA 1LUNA 2OZOA 3T04A 4JE4A 2MQIA 2ETZA 2HMHA 2XP1A 3GXXA 1A1AA 3IN7A 4F5BA 1UURA 5KAZA 2PLEA 3N8MA 2MRKA 5IBMA 3GXWA 4H34A 2JYQA 1OPKA 4K11A 1HCSB 2Y1NA 1D1ZA 1CSZA 1QG1E 2DX0A 4GWFA 1O4HA 5EHRA 1IJRA 2PTKA 1A1BA 2DLYA 2KGYA 4DGXA 1LKLA 1SHDA 1K9AA 1MW4A 1O44A 1AYDA 5GJHA 1QADA 1LUIA 2H8HA 1BLJA 4H1OA
chains in the Genus database with same CATH topology
3VRYA 1BFIA 3UYOA 3S9KA 3QWXX 3PQZA 1NZVA 2CRHA 3IMDA 2AOBA 3MXCA 1WQUA 1LUKA 1A1CA 3VRPA 3OB2B 3PJPA 4GL9E 1BM2A 1O4OA 1O4MA 1O49A 1SPRA 1CJ1A 1FU5A 1O4BA 1O4LA 3MXYA 1O4IA 1SHAA 3VS5A 2H5KA 1YVHA 2RORA 1O4FA 1GRIA 1BMBA 4XZ1A 1SPSA 1CSYA 3PSJA 1D4WA 2HUWA 4FL3A 3PFVA 5GJIA 1O4EA 1O4CA 2MK2A 5AULA 3BUOB 3EACA 3VS6A 2L4KA 4P9ZA 4OHLA 4A4CA 1LKKA 2DCRA 1FU6A 3CBLA 1BFJA 3CXLA 5DC9A 2RSYA 1O4JA 1BKLA 1UUSA 1FHSA 4OHDA 1NZLA 2MRJA 3HIZB 2EKXA 3US4A 2YU7A 4OHHA 1O4NA 1PICA 3VS2A 2CIAA 4LUDA 3BUNB 1TCEA 1AOUF 4E93A 3BKBA 2LQWA 1AOTF 2L3TA 3QWYA 1AYAA 1BHHB 2HDXA 5HKWA 2KK6A 1FBVA 4M4ZA 5EHPA 1SKJA 2EO3A 1RPYA 3NHNA 3WA4A 5CDWA 1BHFA 4U17A 4D8KA 1Y57A 1JU5A 4EIHA 2H46E 3VRNA 2FO0A 1GHUA 1KSWA 1O47A 4ROJA 1IS0A 1JYUA 2CI8A 3N7YA 1G83A 1FYRA 1NRVA 1R1SA 4JEGA 4WWQA 1H9OA 3UF4A 3OP0A 5DF6A 1Y1UA 2ABLA 2C0IA 3M7FA 1BLKA 2B3OA 1CWEA 2K79B 1KA6A 1LCJA 4P9VA 1O46A 1QCFA 1TZEE 2ECDA 4E68A 1RJAA 4K44A 2Y3AB 1JYRA 4EY0A 5AXIA 4X6SA 5EELA 2LNWA 3K2MA 1R1QA 4JGHA 1O45A 4XZ0A 2GE9A 2AUGA 4K2RA 1O4RA 5HKYA 3BUMB 1X6CA 1B47A 3TL0A 2DM0A 3CD3A 2K7AB 1JYQA 1OO3A 1A81A 5J3XA 1AD5A 5I6VA 2VIFA 4FBNA 2AOAA 1M61A 3KFJA 2YSXA 5EEQA 2MC1A 2PNBA 3TKZA 1CWDL 3VS7A 2C9WA 3MAZA 1LCKA 1O4KA 4OHIA 1BHHA 3GQIB 3PLFB 2RVFA 2SHPA 1BF5A 1O4QA 3VS1A 1O48A 2CS0A 1O42A 3VROA 2LCTA 5HKZA 1OPLA 1RQQC 5IBSA 1AYBA 4U1PA 1KC2A 2C0TA 2CR4A 4LUEA 2GSBA 2HCKA 3VGOA 3VS3A 1X0NA 3VRRA 1A08A 4F59A 1KA7A 1SHBA 3HCKA 2RMXA 4A4BA 1O41A 4TZIA 1BKMA 1P13A 1R1PA 5D0JA 2EL8A 2HDVA 3PS5A 2FCIA 1BG1A 5DC4A 5EG3B 3N84A 1M27A 2DVJA 2EYVA 2DLZA 1X27A 3S8NA 3BUXB 1I3ZA 2PNAA 3VRZA 2EYZA 1ZFPE 1A1EA 3S8OA 1YVLA 2IZVA 4NWGA 3OVEA 1F1WA 2LQNA 2BBUA 4NWFA 2PLDA 2C0OA 1MILA 2CBLA 1A07A 1JWOA 2EOBA 3VS4A 3IN8A 2QMSA 2OQ1A 1XA6A 4F5AA 2KNOA 2IUIA 3VS0A 3S8LA 1AYCA 1O4GA 5BO4A 2EO6A 4FL2A 3VRQA 3OV1A 3OB1B 2EYYA 2SRCA 1OO4A 1O4PA 1D4TA 2Y1MA 4K45A 3BUWB 4OHEA 3IMJA 1Z3KA 4QSYA 3PSKA 2L6KA 1HCTB 3C7IA 2CI9A 2LNXA 1O4AA 1FMKA 2EU0A 1F2FA 3EAZA 2IUGA 3HHMB 1FBZA 4GPLB 3ZNIA 1AB2A 5DC0B 4DGPA 4L1BB 1LUMA 1A09A 1O4DA 1O43A 2IUHA 3CWGA 1LUNA 2OZOA 3T04A 4JE4A 2MQIA 2ETZA 2HMHA 2XP1A 3GXXA 1A1AA 3IN7A 4F5BA 1UURA 5KAZA 2PLEA 3N8MA 2MRKA 5IBMA 3GXWA 4H34A 2JYQA 1OPKA 4K11A 1HCSB 2Y1NA 1D1ZA 1CSZA 1QG1E 2DX0A 4GWFA 1O4HA 5EHRA 1IJRA 2PTKA 1A1BA 2DLYA 4DGXA 1LKLA 1SHDA 1K9AA 1MW4A 1O44A 1AYDA 5GJHA 1QADA 1LUIA 2H8HA 1BLJA 4H1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VRY A;  1BFI A;  3UYO A;  3S9K A;  3QWX X;  3PQZ A;  1NZV A;  2CRH A;  3IMD A;  2AOB A;  3MXC A;  1WQU A;  1LUK A;  1A1C A;  3VRP A;  3OB2 B;  3PJP A;  4GL9 E;  1BM2 A;  1O4O A;  1O4M A;  1O49 A;  1SPR A;  1CJ1 A;  1FU5 A;  1O4B A;  1O4L A;  3MXY A;  1O4I A;  1SHA A;  3VS5 A;  2H5K A;  1YVH A;  2ROR A;  1O4F A;  1GRI A;  1BMB A;  4XZ1 A;  1SPS A;  1CSY A;  3PSJ A;  1D4W A;  2HUW A;  4FL3 A;  3PFV A;  5GJI A;  1O4E A;  1O4C A;  2MK2 A;  5AUL A;  3BUO B;  3EAC A;  3VS6 A;  2L4K A;  4P9Z A;  4OHL A;  4A4C A;  1LKK A;  2DCR A;  1FU6 A;  3CBL A;  1BFJ A;  3CXL A;  5DC9 A;  2RSY A;  1O4J A;  1BKL A;  1UUS A;  1FHS A;  4OHD A;  1NZL A;  2MRJ A;  3HIZ B;  2EKX A;  3US4 A;  2YU7 A;  4OHH A;  1O4N A;  1PIC A;  3VS2 A;  2CIA A;  4LUD A;  3BUN B;  1TCE A;  1AOU F;  4E93 A;  3BKB A;  2LQW A;  1AOT F;  2L3T A;  3QWY A;  1AYA A;  1BHH B;  2HDX A;  5HKW A;  2KK6 A;  1FBV A;  4M4Z A;  5EHP A;  1SKJ A;  2EO3 A;  1RPY A;  3NHN A;  3WA4 A;  5CDW A;  1BHF A;  4U17 A;  4D8K A;  1Y57 A;  1JU5 A;  4EIH A;  2H46 E;  3VRN A;  2FO0 A;  1GHU A;  1KSW A;  1O47 A;  4ROJ A;  1IS0 A;  1JYU A;  2CI8 A;  3N7Y A;  1G83 A;  1FYR A;  1NRV A;  1R1S A;  4JEG A;  4WWQ A;  1H9O A;  3UF4 A;  3OP0 A;  5DF6 A;  1Y1U A;  2ABL A;  2C0I A;  3M7F A;  1BLK A;  2B3O A;  1CWE A;  2K79 B;  1KA6 A;  1LCJ A;  4P9V A;  1O46 A;  1QCF A;  1TZE E;  2ECD A;  4E68 A;  1RJA A;  4K44 A;  2Y3A B;  1JYR A;  4EY0 A;  5AXI A;  4X6S A;  5EEL A;  2LNW A;  3K2M A;  1R1Q A;  4JGH A;  1O45 A;  4XZ0 A;  2GE9 A;  2AUG A;  4K2R A;  1O4R A;  5HKY A;  3BUM B;  1X6C A;  1B47 A;  3TL0 A;  2DM0 A;  3CD3 A;  2K7A B;  1JYQ A;  1OO3 A;  1A81 A;  5J3X A;  1AD5 A;  5I6V A;  2VIF A;  4FBN A;  2AOA A;  1M61 A;  3KFJ A;  2YSX A;  5EEQ A;  2MC1 A;  2PNB A;  3TKZ A;  1CWD L;  3VS7 A;  2C9W A;  3MAZ A;  1LCK A;  1O4K A;  4OHI A;  1BHH A;  3GQI B;  3PLF B;  2RVF A;  2SHP A;  1BF5 A;  1O4Q A;  3VS1 A;  1O48 A;  2CS0 A;  1O42 A;  3VRO A;  2LCT A;  5HKZ A;  1OPL A;  1RQQ C;  5IBS A;  1AYB A;  4U1P A;  1KC2 A;  2C0T A;  2CR4 A;  4LUE A;  2GSB A;  2HCK A;  3VGO A;  3VS3 A;  1X0N A;  3VRR A;  1A08 A;  4F59 A;  1KA7 A;  1SHB A;  3HCK A;  2RMX A;  4A4B A;  1O41 A;  4TZI A;  1BKM A;  1P13 A;  1R1P A;  5D0J A;  2EL8 A;  2HDV A;  3PS5 A;  2FCI A;  1BG1 A;  5DC4 A;  5EG3 B;  3N84 A;  1M27 A;  2DVJ A;  2EYV A;  2DLZ A;  1X27 A;  3S8N A;  3BUX B;  1I3Z A;  2PNA A;  3VRZ A;  2EYZ A;  1ZFP E;  1A1E A;  3S8O A;  1YVL A;  2IZV A;  4NWG A;  3OVE A;  1F1W A;  2LQN A;  2BBU A;  4NWF A;  2PLD A;  2C0O A;  1MIL A;  2CBL A;  1A07 A;  1JWO A;  2EOB A;  3VS4 A;  3IN8 A;  2QMS A;  2OQ1 A;  1XA6 A;  4F5A A;  2KNO A;  2IUI A;  3VS0 A;  3S8L A;  1AYC A;  1O4G A;  5BO4 A;  2EO6 A;  4FL2 A;  3VRQ A;  3OV1 A;  3OB1 B;  2EYY A;  2SRC A;  1OO4 A;  1O4P A;  1D4T A;  2Y1M A;  4K45 A;  3BUW B;  4OHE A;  3IMJ A;  1Z3K A;  4QSY A;  3PSK A;  2L6K A;  1HCT B;  3C7I A;  2CI9 A;  2LNX A;  1O4A A;  1FMK A;  2EU0 A;  1F2F A;  3EAZ A;  2IUG A;  3HHM B;  1FBZ A;  4GPL B;  3ZNI A;  1AB2 A;  5DC0 B;  4DGP A;  4L1B B;  1LUM A;  1A09 A;  1O4D A;  1O43 A;  2IUH A;  3CWG A;  1LUN A;  2OZO A;  3T04 A;  4JE4 A;  2MQI A;  2ETZ A;  2HMH A;  2XP1 A;  3GXX A;  1A1A A;  3IN7 A;  4F5B A;  1UUR A;  5KAZ A;  2PLE A;  3N8M A;  2MRK A;  5IBM A;  3GXW A;  4H34 A;  2JYQ A;  1OPK A;  4K11 A;  1HCS B;  2Y1N A;  1D1Z A;  1CSZ A;  1QG1 E;  2DX0 A;  4GWF A;  1O4H A;  5EHR A;  1IJR A;  2PTK A;  1A1B A;  2DLY A;  4DGX A;  1LKL A;  1SHD A;  1K9A A;  1MW4 A;  1O44 A;  1AYD A;  5GJH A;  1QAD A;  1LUI A;  2H8H A;  1BLJ A;  4H1O A; 
#chains in the Genus database with same CATH topology
 3VRY A;  1BFI A;  3UYO A;  3S9K A;  3QWX X;  3PQZ A;  1NZV A;  2CRH A;  3IMD A;  2AOB A;  3MXC A;  1WQU A;  1LUK A;  1A1C A;  3VRP A;  3OB2 B;  3PJP A;  4GL9 E;  1BM2 A;  1O4O A;  1O4M A;  1O49 A;  1SPR A;  1CJ1 A;  1FU5 A;  1O4B A;  1O4L A;  3MXY A;  1O4I A;  1SHA A;  2LRA A;  3VS5 A;  2H5K A;  1YVH A;  2ROR A;  1O4F A;  1GRI A;  1BMB A;  4XZ1 A;  1SPS A;  1CSY A;  3PSJ A;  1D4W A;  2HUW A;  4FL3 A;  3PFV A;  5GJI A;  1O4E A;  1O4C A;  2MK2 A;  5AUL A;  3BUO B;  3EAC A;  3VS6 A;  2L4K A;  4P9Z A;  4OHL A;  4A4C A;  1LKK A;  2DCR A;  1FU6 A;  3CBL A;  1BFJ A;  3CXL A;  5DC9 A;  2RSY A;  1O4J A;  1BKL A;  1UUS A;  1FHS A;  4OHD A;  1NZL A;  2MRJ A;  3HIZ B;  2EKX A;  3US4 A;  2YU7 A;  4OHH A;  1O4N A;  1PIC A;  3VS2 A;  2CIA A;  4LUD A;  3BUN B;  1TCE A;  1AOU F;  4E93 A;  3BKB A;  2LQW A;  1AOT F;  2L3T A;  3QWY A;  1AYA A;  1BHH B;  2HDX A;  5HKW A;  2KK6 A;  1FBV A;  4M4Z A;  5EHP A;  1SKJ A;  2EO3 A;  1RPY A;  3NHN A;  3WA4 A;  5CDW A;  1BHF A;  4U17 A;  4D8K A;  1Y57 A;  1JU5 A;  4EIH A;  2H46 E;  3VRN A;  2FO0 A;  1GHU A;  1KSW A;  1O47 A;  4ROJ A;  1IS0 A;  1JYU A;  2CI8 A;  3N7Y A;  1G83 A;  1FYR A;  1NRV A;  1R1S A;  4JEG A;  3LYV A;  4WWQ A;  1H9O A;  3UF4 A;  3OP0 A;  5DF6 A;  1Y1U A;  2ABL A;  2C0I A;  3M7F A;  1BLK A;  2B3O A;  1CWE A;  2K79 B;  1KA6 A;  1LCJ A;  4P9V A;  1O46 A;  1QCF A;  1TZE E;  2ECD A;  4E68 A;  1RJA A;  4K44 A;  2Y3A B;  1JYR A;  4EY0 A;  5AXI A;  4X6S A;  5EEL A;  2LNW A;  3K2M A;  1R1Q A;  4JGH A;  1O45 A;  4XZ0 A;  2GE9 A;  2AUG A;  4K2R A;  1O4R A;  5HKY A;  3BUM B;  1X6C A;  1B47 A;  3TL0 A;  2DM0 A;  3CD3 A;  2K7A B;  1JYQ A;  1OO3 A;  1A81 A;  5J3X A;  1AD5 A;  5I6V A;  2VIF A;  4FBN A;  2AOA A;  1M61 A;  3KFJ A;  2YSX A;  5EEQ A;  2MC1 A;  2PNB A;  3TKZ A;  1CWD L;  3VS7 A;  2C9W A;  3MAZ A;  1LCK A;  1O4K A;  4OHI A;  1BHH A;  3GQI B;  3PLF B;  2RVF A;  2SHP A;  1BF5 A;  1O4Q A;  3VS1 A;  1O48 A;  2CS0 A;  1O42 A;  3VRO A;  2LCT A;  5HKZ A;  1OPL A;  1RQQ C;  5IBS A;  1AYB A;  4U1P A;  1KC2 A;  2C0T A;  2CR4 A;  4LUE A;  2GSB A;  2HCK A;  3VGO A;  3VS3 A;  1X0N A;  3VRR A;  1A08 A;  4F59 A;  1KA7 A;  1SHB A;  3HCK A;  2RMX A;  4A4B A;  1O41 A;  4TZI A;  1BKM A;  1P13 A;  1R1P A;  5D0J A;  2EL8 A;  2HDV A;  3PS5 A;  2FCI A;  1BG1 A;  3K2T A;  5DC4 A;  5EG3 B;  3N84 A;  1M27 A;  2DVJ A;  2EYV A;  2DLZ A;  1X27 A;  3S8N A;  3BUX B;  1I3Z A;  2PNA A;  3VRZ A;  2EYZ A;  1ZFP E;  1A1E A;  3S8O A;  1YVL A;  2IZV A;  4NWG A;  3OVE A;  1F1W A;  2LQN A;  2BBU A;  4NWF A;  2PLD A;  2C0O A;  1MIL A;  2CBL A;  1A07 A;  1JWO A;  2EOB A;  3VS4 A;  3IN8 A;  2QMS A;  2OQ1 A;  1XA6 A;  4F5A A;  2KNO A;  2IUI A;  3VS0 A;  3S8L A;  1AYC A;  1O4G A;  5BO4 A;  2EO6 A;  4FL2 A;  3VRQ A;  3OV1 A;  3OB1 B;  2EYY A;  2SRC A;  1OO4 A;  1O4P A;  1D4T A;  2Y1M A;  4K45 A;  3BUW B;  4OHE A;  3IMJ A;  1Z3K A;  4QSY A;  3PSK A;  2L6K A;  1HCT B;  3C7I A;  2CI9 A;  2LNX A;  1O4A A;  1FMK A;  2EU0 A;  1F2F A;  3EAZ A;  2IUG A;  3HHM B;  1FBZ A;  4GPL B;  3ZNI A;  1AB2 A;  5DC0 B;  4DGP A;  4L1B B;  1LUM A;  1A09 A;  1O4D A;  1O43 A;  2IUH A;  3CWG A;  1LUN A;  2OZO A;  3T04 A;  4JE4 A;  2MQI A;  2ETZ A;  2HMH A;  2XP1 A;  3GXX A;  1A1A A;  3IN7 A;  4F5B A;  1UUR A;  5KAZ A;  2PLE A;  3N8M A;  2MRK A;  5IBM A;  3GXW A;  4H34 A;  2JYQ A;  1OPK A;  4K11 A;  1HCS B;  2Y1N A;  1D1Z A;  1CSZ A;  1QG1 E;  2DX0 A;  4GWF A;  1O4H A;  5EHR A;  1IJR A;  2PTK A;  1A1B A;  2DLY A;  2KGY A;  4DGX A;  1LKL A;  1SHD A;  1K9A A;  1MW4 A;  1O44 A;  1AYD A;  5GJH A;  1QAD A;  1LUI A;  2H8H A;  1BLJ A;  4H1O A; 
#chains in the Genus database with same CATH homology
 3VRY A;  1BFI A;  3UYO A;  3S9K A;  3QWX X;  3PQZ A;  1NZV A;  2CRH A;  3IMD A;  2AOB A;  3MXC A;  1WQU A;  1LUK A;  1A1C A;  3VRP A;  3OB2 B;  3PJP A;  4GL9 E;  1BM2 A;  1O4O A;  1O4M A;  1O49 A;  1SPR A;  1CJ1 A;  1FU5 A;  1O4B A;  1O4L A;  3MXY A;  1O4I A;  1SHA A;  3VS5 A;  2H5K A;  1YVH A;  2ROR A;  1O4F A;  1GRI A;  1BMB A;  4XZ1 A;  1SPS A;  1CSY A;  3PSJ A;  1D4W A;  2HUW A;  4FL3 A;  3PFV A;  5GJI A;  1O4E A;  1O4C A;  2MK2 A;  5AUL A;  3BUO B;  3EAC A;  3VS6 A;  2L4K A;  4P9Z A;  4OHL A;  4A4C A;  1LKK A;  2DCR A;  1FU6 A;  3CBL A;  1BFJ A;  3CXL A;  5DC9 A;  2RSY A;  1O4J A;  1BKL A;  1UUS A;  1FHS A;  4OHD A;  1NZL A;  2MRJ A;  3HIZ B;  2EKX A;  3US4 A;  2YU7 A;  4OHH A;  1O4N A;  1PIC A;  3VS2 A;  2CIA A;  4LUD A;  3BUN B;  1TCE A;  1AOU F;  4E93 A;  3BKB A;  2LQW A;  1AOT F;  2L3T A;  3QWY A;  1AYA A;  1BHH B;  2HDX A;  5HKW A;  2KK6 A;  1FBV A;  4M4Z A;  5EHP A;  1SKJ A;  2EO3 A;  1RPY A;  3NHN A;  3WA4 A;  5CDW A;  1BHF A;  4U17 A;  4D8K A;  1Y57 A;  1JU5 A;  4EIH A;  2H46 E;  3VRN A;  2FO0 A;  1GHU A;  1KSW A;  1O47 A;  4ROJ A;  1IS0 A;  1JYU A;  2CI8 A;  3N7Y A;  1G83 A;  1FYR A;  1NRV A;  1R1S A;  4JEG A;  4WWQ A;  1H9O A;  3UF4 A;  3OP0 A;  5DF6 A;  1Y1U A;  2ABL A;  2C0I A;  3M7F A;  1BLK A;  2B3O A;  1CWE A;  2K79 B;  1KA6 A;  1LCJ A;  4P9V A;  1O46 A;  1QCF A;  1TZE E;  2ECD A;  4E68 A;  1RJA A;  4K44 A;  2Y3A B;  1JYR A;  4EY0 A;  5AXI A;  4X6S A;  5EEL A;  2LNW A;  3K2M A;  1R1Q A;  4JGH A;  1O45 A;  4XZ0 A;  2GE9 A;  2AUG A;  4K2R A;  1O4R A;  5HKY A;  3BUM B;  1X6C A;  1B47 A;  3TL0 A;  2DM0 A;  3CD3 A;  2K7A B;  1JYQ A;  1OO3 A;  1A81 A;  5J3X A;  1AD5 A;  5I6V A;  2VIF A;  4FBN A;  2AOA A;  1M61 A;  3KFJ A;  2YSX A;  5EEQ A;  2MC1 A;  2PNB A;  3TKZ A;  1CWD L;  3VS7 A;  2C9W A;  3MAZ A;  1LCK A;  1O4K A;  4OHI A;  1BHH A;  3GQI B;  3PLF B;  2RVF A;  2SHP A;  1BF5 A;  1O4Q A;  3VS1 A;  1O48 A;  2CS0 A;  1O42 A;  3VRO A;  2LCT A;  5HKZ A;  1OPL A;  1RQQ C;  5IBS A;  1AYB A;  4U1P A;  1KC2 A;  2C0T A;  2CR4 A;  4LUE A;  2GSB A;  2HCK A;  3VGO A;  3VS3 A;  1X0N A;  3VRR A;  1A08 A;  4F59 A;  1KA7 A;  1SHB A;  3HCK A;  2RMX A;  4A4B A;  1O41 A;  4TZI A;  1BKM A;  1P13 A;  1R1P A;  5D0J A;  2EL8 A;  2HDV A;  3PS5 A;  2FCI A;  1BG1 A;  5DC4 A;  5EG3 B;  3N84 A;  1M27 A;  2DVJ A;  2EYV A;  2DLZ A;  1X27 A;  3S8N A;  3BUX B;  1I3Z A;  2PNA A;  3VRZ A;  2EYZ A;  1ZFP E;  1A1E A;  3S8O A;  1YVL A;  2IZV A;  4NWG A;  3OVE A;  1F1W A;  2LQN A;  2BBU A;  4NWF A;  2PLD A;  2C0O A;  1MIL A;  2CBL A;  1A07 A;  1JWO A;  2EOB A;  3VS4 A;  3IN8 A;  2QMS A;  2OQ1 A;  1XA6 A;  4F5A A;  2KNO A;  2IUI A;  3VS0 A;  3S8L A;  1AYC A;  1O4G A;  5BO4 A;  2EO6 A;  4FL2 A;  3VRQ A;  3OV1 A;  3OB1 B;  2EYY A;  2SRC A;  1OO4 A;  1O4P A;  1D4T A;  2Y1M A;  4K45 A;  3BUW B;  4OHE A;  3IMJ A;  1Z3K A;  4QSY A;  3PSK A;  2L6K A;  1HCT B;  3C7I A;  2CI9 A;  2LNX A;  1O4A A;  1FMK A;  2EU0 A;  1F2F A;  3EAZ A;  2IUG A;  3HHM B;  1FBZ A;  4GPL B;  3ZNI A;  1AB2 A;  5DC0 B;  4DGP A;  4L1B B;  1LUM A;  1A09 A;  1O4D A;  1O43 A;  2IUH A;  3CWG A;  1LUN A;  2OZO A;  3T04 A;  4JE4 A;  2MQI A;  2ETZ A;  2HMH A;  2XP1 A;  3GXX A;  1A1A A;  3IN7 A;  4F5B A;  1UUR A;  5KAZ A;  2PLE A;  3N8M A;  2MRK A;  5IBM A;  3GXW A;  4H34 A;  2JYQ A;  1OPK A;  4K11 A;  1HCS B;  2Y1N A;  1D1Z A;  1CSZ A;  1QG1 E;  2DX0 A;  4GWF A;  1O4H A;  5EHR A;  1IJR A;  2PTK A;  1A1B A;  2DLY A;  4DGX A;  1LKL A;  1SHD A;  1K9A A;  1MW4 A;  1O44 A;  1AYD A;  5GJH A;  1QAD A;  1LUI A;  2H8H A;  1BLJ A;  4H1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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