2IUHA

Crystal structure of the pi3-kinase p85 n-terminal sh2 domain in complex with c-kit phosphotyrosyl peptide
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
115
structure length
115
Chain Sequence
NMSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
total genus 32
structure length 115
sequence length 115
ec nomenclature
pdb deposition date 2006-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2iuhA00
2FCIA 1JYRA 2LNXA 1O4DA 1LCKA 2KK6A 1O4QA 1O4IA 1WQUA 3BUMB 2PNAA 1F2FA 1TCEA 2AOBA 2DX0A 2AOAA 1BFIA 1KA6A 1I3ZA 3BKBA 1BF5A 4L1BB 3PLFB 1O44A 3BUWB 1BG1A 2MRKA 1R1PA 4LUDA 4P9ZA 5GJIA 4U17A 2OZOA 3OV1A 1LUNA 3HCKA 3US4A 5HKZA 1LKLA 1P13A 3VGOA 2CI8A 2MC1A 4NWFA 1RPYA 4X6SA 1A1CA 1QG1E 4EY0A 1AOUF 1RQQC 2C9WA 4H34A 2JYQA 2DLZA 2MK2A 1BLJA 3VRZA 3N84A 1O4HA 3VS0A 3CXLA 1D4WA 2K79B 3VS7A 3GQIB 1ZFPE 1Y57A 5HKYA 2LNWA 2EOBA 3PSKA 1MW4A 4JEGA 1JWOA 4OHEA 4LUEA 2CS0A 4A4CA 1O4NA 2BBUA 2HDXA 1LUMA 3KFJA 5DC9A 3VRNA 2IUIA 2RORA 3VS5A 4E93A 1UURA 3PFVA 1KSWA 1BHHB 1O4PA 2H8HA 2L6KA 2DLYA 4OHLA 2EYYA 2PLDA 2IUHA 3GXWA 3WA4A 1X0NA 3N7YA 3MXYA 1O4FA 1IJRA 2YSXA 4F59A 5D0JA 3PSJA 1BKLA 1RJAA 2GSBA 2EYZA 1LKKA 3OVEA 4JGHA 1AYAA 1A07A 3VS4A 1MILA 2B3OA 2MRJA 1R1SA 2GE9A 1JYUA 1A81A 1A08A 1O43A 3VRYA 2RVFA 1SPRA 2RSYA 1FHSA 1JU5A 2YU7A 2PLEA 3OB1B 1QCFA 4XZ0A 3T04A 3TL0A 1Z3KA 2DVJA 1O4BA 2Y1NA 4P9VA 4OHHA 4F5BA 1O41A 1O45A 2OQ1A 1BM2A 1A1AA 2EU0A 2CI9A 1F1WA 3OP0A 4D8KA 3EAZA 2CRHA 1AD5A 1UUSA 1O4AA 1XA6A 3CWGA 3VRQA 5AXIA 2Y3AB 1O4GA 2IUGA 1IS0A 2L4KA 1O46A 1Y1UA 1O4JA 1TZEE 5AULA 5DF6A 1O49A 3C7IA 3VRPA 3S9KA 2K7AB 1GRIA 3IMDA 2L3TA 3VROA 4U1PA 1PICA 4TZIA 2IZVA 2DM0A 5EHRA 3BUOB 5BO4A 3VS3A 4GWFA 4FL3A 5IBSA 1HCTB 2SHPA 1O4EA 3IMJA 3VS2A 1AYBA 1BLKA 3BUXB 2HCKA 1JYQA 2C0IA 3QWXX 1B47A 5J3XA 3UF4A 1SHDA 1FBVA 1G83A 1O4RA 1NRVA 1A09A 1LUKA 1O47A 1O48A 1OO4A 3PQZA 4M4ZA 1O4KA 2EKXA 1BKMA 1CJ1A 4QSYA 1GHUA 3NHNA 4WWQA 4E68A 4H1OA 1O4MA 1KC2A 3MAZA 2QMSA 2CIAA 1OPKA 1H9OA 2HDVA 2Y1MA 1NZLA 3QWYA 2PNBA 4FBNA 2KNOA 1O4OA 4K44A 2PTKA 2VIFA 5HKWA 1FYRA 1X6CA 5KAZA 1AB2A 1CSZA 1BMBA 2EYVA 2LCTA 3ZNIA 1FU6A 1SPSA 1K9AA 1YVHA 4GL9E 2ABLA 1FU5A 4FL2A 4ROJA 5CDWA 1AYDA 3HIZB 2ETZA 5DC0B 2ECDA 4XZ1A 3K2MA 2H5KA 3TKZA 1D1ZA 1O42A 2XP1A 4OHIA 1A1BA 1KA7A 1SHBA 1M61A 1CWEA 3OB2B 1X27A 1R1QA 1LCJA 5GJHA 1SHAA 2C0TA 5DC4A 2HMHA 1FMKA 3VRRA 4A4BA 4NWGA 3VS6A 1BHFA 2EL8A 3S8OA 2DCRA 2CR4A 3IN8A 4EIHA 5EG3B 2HUWA 3VS1A 4DGXA 3BUNB 3PS5A 1QADA 5EELA 2RMXA 2H46E 1FBZA 2C0OA 1OO3A 1A1EA 3CD3A 2SRCA 2MQIA 1HCSB 2CBLA 2EO3A 4OHDA 4K45A 1LUIA 5EEQA 3M7FA 3S8NA 5IBMA 3MXCA 3CBLA 5I6VA 1NZVA 3IN7A 2AUGA 1SKJA 1CWDL 1D4TA 2FO0A 4GPLB 4JE4A 1AOTF 1BHHA 3UYOA 1O4CA 1AYCA 3HHMB 2LQWA 4DGPA 3EACA 3PJPA 4K11A 4F5AA 2LQNA 1YVLA 5EHPA 3S8LA 1CSYA 4K2RA 3GXXA 2EO6A 1M27A 1OPLA 1BFJA 1O4LA 3N8MA
chains in the Genus database with same CATH superfamily
2FCIA 1JYRA 2LNXA 1O4DA 1LCKA 2KK6A 1O4QA 1O4IA 1WQUA 3BUMB 2PNAA 1F2FA 1TCEA 2AOBA 2DX0A 2AOAA 1BFIA 1KA6A 1I3ZA 3BKBA 1BF5A 4L1BB 3PLFB 1O44A 3BUWB 1BG1A 2MRKA 1R1PA 4LUDA 4P9ZA 5GJIA 4U17A 2OZOA 3OV1A 1LUNA 3HCKA 3US4A 5HKZA 1LKLA 1P13A 3VGOA 2CI8A 2MC1A 4NWFA 1RPYA 4X6SA 1A1CA 1QG1E 4EY0A 1AOUF 1RQQC 2C9WA 4H34A 2JYQA 2DLZA 2MK2A 1BLJA 3VRZA 3N84A 1O4HA 3VS0A 3CXLA 1D4WA 2K79B 3VS7A 3GQIB 1ZFPE 1Y57A 5HKYA 2LNWA 2EOBA 3PSKA 1MW4A 4JEGA 1JWOA 4OHEA 4LUEA 2CS0A 4A4CA 1O4NA 2BBUA 2HDXA 1LUMA 3KFJA 5DC9A 3VRNA 2IUIA 2RORA 3VS5A 4E93A 1UURA 3PFVA 1KSWA 1BHHB 1O4PA 2H8HA 2L6KA 2DLYA 4OHLA 2EYYA 2PLDA 2IUHA 3GXWA 3WA4A 1X0NA 3N7YA 3MXYA 1O4FA 1IJRA 2YSXA 4F59A 5D0JA 3PSJA 1BKLA 1RJAA 2GSBA 2EYZA 1LKKA 3OVEA 4JGHA 1AYAA 1A07A 3VS4A 1MILA 2B3OA 2MRJA 1R1SA 2GE9A 1JYUA 1A81A 1A08A 1O43A 3VRYA 2RVFA 2KGYA 1SPRA 2RSYA 1FHSA 1JU5A 2YU7A 2PLEA 3OB1B 1QCFA 4XZ0A 3T04A 3TL0A 1Z3KA 2DVJA 1O4BA 2Y1NA 4P9VA 4OHHA 4F5BA 1O41A 1O45A 2OQ1A 1BM2A 1A1AA 2EU0A 2CI9A 1F1WA 3OP0A 4D8KA 3EAZA 2CRHA 1AD5A 1UUSA 1O4AA 1XA6A 3LYVA 3CWGA 3VRQA 5AXIA 2Y3AB 1O4GA 2IUGA 1IS0A 2L4KA 1O46A 1Y1UA 1O4JA 1TZEE 5AULA 5DF6A 1O49A 3C7IA 3VRPA 3S9KA 2K7AB 1GRIA 3IMDA 2L3TA 3VROA 4U1PA 1PICA 4TZIA 2IZVA 2DM0A 5EHRA 3BUOB 5BO4A 3VS3A 4GWFA 4FL3A 5IBSA 1HCTB 2SHPA 1O4EA 3IMJA 3VS2A 1AYBA 1BLKA 3BUXB 2HCKA 1JYQA 2C0IA 3QWXX 1B47A 5J3XA 3UF4A 1SHDA 1FBVA 1G83A 1O4RA 1NRVA 1A09A 1LUKA 1O47A 1O48A 1OO4A 3PQZA 4M4ZA 1O4KA 2EKXA 1BKMA 1CJ1A 4QSYA 1GHUA 3NHNA 4WWQA 4E68A 4H1OA 1O4MA 1KC2A 3MAZA 2QMSA 2CIAA 1OPKA 1H9OA 2HDVA 2Y1MA 1NZLA 3QWYA 2PNBA 4FBNA 2KNOA 1O4OA 4K44A 2PTKA 2VIFA 5HKWA 1FYRA 1X6CA 5KAZA 1AB2A 1CSZA 1BMBA 2EYVA 2LCTA 3ZNIA 1FU6A 1SPSA 1K9AA 1YVHA 4GL9E 2LRAA 2ABLA 1FU5A 4FL2A 4ROJA 5CDWA 1AYDA 3HIZB 2ETZA 5DC0B 2ECDA 4XZ1A 3K2MA 2H5KA 3TKZA 1D1ZA 1O42A 2XP1A 4OHIA 1A1BA 1KA7A 1SHBA 1M61A 1CWEA 3OB2B 1X27A 1R1QA 1LCJA 5GJHA 1SHAA 2C0TA 5DC4A 2HMHA 1FMKA 3VRRA 4A4BA 4NWGA 3VS6A 1BHFA 2EL8A 3S8OA 2DCRA 2CR4A 3IN8A 4EIHA 5EG3B 2HUWA 3VS1A 4DGXA 3BUNB 3PS5A 1QADA 5EELA 2RMXA 2H46E 1FBZA 2C0OA 1OO3A 1A1EA 3CD3A 2SRCA 2MQIA 1HCSB 2CBLA 2EO3A 4OHDA 4K45A 1LUIA 5EEQA 3M7FA 3S8NA 5IBMA 3MXCA 3CBLA 5I6VA 1NZVA 3IN7A 2AUGA 1SKJA 3K2TA 1CWDL 1D4TA 2FO0A 4GPLB 4JE4A 1AOTF 1BHHA 3UYOA 1O4CA 1AYCA 3HHMB 2LQWA 4DGPA 3EACA 3PJPA 4K11A 4F5AA 2LQNA 1YVLA 5EHPA 3S8LA 1CSYA 4K2RA 3GXXA 2EO6A 1M27A 1OPLA 1BFJA 1O4LA 3N8MA
chains in the Genus database with same CATH topology
2FCIA 1JYRA 2LNXA 1O4DA 1LCKA 2KK6A 1O4QA 1O4IA 1WQUA 3BUMB 2PNAA 1F2FA 1TCEA 2AOBA 2DX0A 2AOAA 1BFIA 1KA6A 1I3ZA 3BKBA 1BF5A 4L1BB 3PLFB 1O44A 3BUWB 1BG1A 2MRKA 1R1PA 4LUDA 4P9ZA 5GJIA 4U17A 2OZOA 3OV1A 1LUNA 3HCKA 3US4A 5HKZA 1LKLA 1P13A 3VGOA 2CI8A 2MC1A 4NWFA 1RPYA 4X6SA 1A1CA 1QG1E 4EY0A 1AOUF 1RQQC 2C9WA 4H34A 2JYQA 2DLZA 2MK2A 1BLJA 3VRZA 3N84A 1O4HA 3VS0A 3CXLA 1D4WA 2K79B 3VS7A 3GQIB 1ZFPE 1Y57A 5HKYA 2LNWA 2EOBA 3PSKA 1MW4A 4JEGA 1JWOA 4OHEA 4LUEA 2CS0A 4A4CA 1O4NA 2BBUA 2HDXA 1LUMA 3KFJA 5DC9A 3VRNA 2IUIA 2RORA 3VS5A 4E93A 1UURA 3PFVA 1KSWA 1BHHB 1O4PA 2H8HA 2L6KA 2DLYA 4OHLA 2EYYA 2PLDA 2IUHA 3GXWA 3WA4A 1X0NA 3N7YA 3MXYA 1O4FA 1IJRA 2YSXA 4F59A 5D0JA 3PSJA 1BKLA 1RJAA 2GSBA 2EYZA 1LKKA 3OVEA 4JGHA 1AYAA 1A07A 3VS4A 1MILA 2B3OA 2MRJA 1R1SA 2GE9A 1JYUA 1A81A 1A08A 1O43A 3VRYA 2RVFA 1SPRA 2RSYA 1FHSA 1JU5A 2YU7A 2PLEA 3OB1B 1QCFA 4XZ0A 3T04A 3TL0A 1Z3KA 2DVJA 1O4BA 2Y1NA 4P9VA 4OHHA 4F5BA 1O41A 1O45A 2OQ1A 1BM2A 1A1AA 2EU0A 2CI9A 1F1WA 3OP0A 4D8KA 3EAZA 2CRHA 1AD5A 1UUSA 1O4AA 1XA6A 3CWGA 3VRQA 5AXIA 2Y3AB 1O4GA 2IUGA 1IS0A 2L4KA 1O46A 1Y1UA 1O4JA 1TZEE 5AULA 5DF6A 1O49A 3C7IA 3VRPA 3S9KA 2K7AB 1GRIA 3IMDA 2L3TA 3VROA 4U1PA 1PICA 4TZIA 2IZVA 2DM0A 5EHRA 3BUOB 5BO4A 3VS3A 4GWFA 4FL3A 5IBSA 1HCTB 2SHPA 1O4EA 3IMJA 3VS2A 1AYBA 1BLKA 3BUXB 2HCKA 1JYQA 2C0IA 3QWXX 1B47A 5J3XA 3UF4A 1SHDA 1FBVA 1G83A 1O4RA 1NRVA 1A09A 1LUKA 1O47A 1O48A 1OO4A 3PQZA 4M4ZA 1O4KA 2EKXA 1BKMA 1CJ1A 4QSYA 1GHUA 3NHNA 4WWQA 4E68A 4H1OA 1O4MA 1KC2A 3MAZA 2QMSA 2CIAA 1OPKA 1H9OA 2HDVA 2Y1MA 1NZLA 3QWYA 2PNBA 4FBNA 2KNOA 1O4OA 4K44A 2PTKA 2VIFA 5HKWA 1FYRA 1X6CA 5KAZA 1AB2A 1CSZA 1BMBA 2EYVA 2LCTA 3ZNIA 1FU6A 1SPSA 1K9AA 1YVHA 4GL9E 2ABLA 1FU5A 4FL2A 4ROJA 5CDWA 1AYDA 3HIZB 2ETZA 5DC0B 2ECDA 4XZ1A 3K2MA 2H5KA 3TKZA 1D1ZA 1O42A 2XP1A 4OHIA 1A1BA 1KA7A 1SHBA 1M61A 1CWEA 3OB2B 1X27A 1R1QA 1LCJA 5GJHA 1SHAA 2C0TA 5DC4A 2HMHA 1FMKA 3VRRA 4A4BA 4NWGA 3VS6A 1BHFA 2EL8A 3S8OA 2DCRA 2CR4A 3IN8A 4EIHA 5EG3B 2HUWA 3VS1A 4DGXA 3BUNB 3PS5A 1QADA 5EELA 2RMXA 2H46E 1FBZA 2C0OA 1OO3A 1A1EA 3CD3A 2SRCA 2MQIA 1HCSB 2CBLA 2EO3A 4OHDA 4K45A 1LUIA 5EEQA 3M7FA 3S8NA 5IBMA 3MXCA 3CBLA 5I6VA 1NZVA 3IN7A 2AUGA 1SKJA 1CWDL 1D4TA 2FO0A 4GPLB 4JE4A 1AOTF 1BHHA 3UYOA 1O4CA 1AYCA 3HHMB 2LQWA 4DGPA 3EACA 3PJPA 4K11A 4F5AA 2LQNA 1YVLA 5EHPA 3S8LA 1CSYA 4K2RA 3GXXA 2EO6A 1M27A 1OPLA 1BFJA 1O4LA 3N8MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FCI A;  1JYR A;  2LNX A;  1O4D A;  1LCK A;  2KK6 A;  1O4Q A;  1O4I A;  1WQU A;  3BUM B;  2PNA A;  1F2F A;  1TCE A;  2AOB A;  2DX0 A;  2AOA A;  1BFI A;  1KA6 A;  1I3Z A;  3BKB A;  1BF5 A;  4L1B B;  3PLF B;  1O44 A;  3BUW B;  1BG1 A;  2MRK A;  1R1P A;  4LUD A;  4P9Z A;  5GJI A;  4U17 A;  2OZO A;  3OV1 A;  1LUN A;  3HCK A;  3US4 A;  5HKZ A;  1LKL A;  1P13 A;  3VGO A;  2CI8 A;  2MC1 A;  4NWF A;  1RPY A;  4X6S A;  1A1C A;  1QG1 E;  4EY0 A;  1AOU F;  1RQQ C;  2C9W A;  4H34 A;  2JYQ A;  2DLZ A;  2MK2 A;  1BLJ A;  3VRZ A;  3N84 A;  1O4H A;  3VS0 A;  3CXL A;  1D4W A;  2K79 B;  3VS7 A;  3GQI B;  1ZFP E;  1Y57 A;  5HKY A;  2LNW A;  2EOB A;  3PSK A;  1MW4 A;  4JEG A;  1JWO A;  4OHE A;  4LUE A;  2CS0 A;  4A4C A;  1O4N A;  2BBU A;  2HDX A;  1LUM A;  3KFJ A;  5DC9 A;  3VRN A;  2IUI A;  2ROR A;  3VS5 A;  4E93 A;  1UUR A;  3PFV A;  1KSW A;  1BHH B;  1O4P A;  2H8H A;  2L6K A;  2DLY A;  4OHL A;  2EYY A;  2PLD A;  2IUH A;  3GXW A;  3WA4 A;  1X0N A;  3N7Y A;  3MXY A;  1O4F A;  1IJR A;  2YSX A;  4F59 A;  5D0J A;  3PSJ A;  1BKL A;  1RJA A;  2GSB A;  2EYZ A;  1LKK A;  3OVE A;  4JGH A;  1AYA A;  1A07 A;  3VS4 A;  1MIL A;  2B3O A;  2MRJ A;  1R1S A;  2GE9 A;  1JYU A;  1A81 A;  1A08 A;  1O43 A;  3VRY A;  2RVF A;  1SPR A;  2RSY A;  1FHS A;  1JU5 A;  2YU7 A;  2PLE A;  3OB1 B;  1QCF A;  4XZ0 A;  3T04 A;  3TL0 A;  1Z3K A;  2DVJ A;  1O4B A;  2Y1N A;  4P9V A;  4OHH A;  4F5B A;  1O41 A;  1O45 A;  2OQ1 A;  1BM2 A;  1A1A A;  2EU0 A;  2CI9 A;  1F1W A;  3OP0 A;  4D8K A;  3EAZ A;  2CRH A;  1AD5 A;  1UUS A;  1O4A A;  1XA6 A;  3CWG A;  3VRQ A;  5AXI A;  2Y3A B;  1O4G A;  2IUG A;  1IS0 A;  2L4K A;  1O46 A;  1Y1U A;  1O4J A;  1TZE E;  5AUL A;  5DF6 A;  1O49 A;  3C7I A;  3VRP A;  3S9K A;  2K7A B;  1GRI A;  3IMD A;  2L3T A;  3VRO A;  4U1P A;  1PIC A;  4TZI A;  2IZV A;  2DM0 A;  5EHR A;  3BUO B;  5BO4 A;  3VS3 A;  4GWF A;  4FL3 A;  5IBS A;  1HCT B;  2SHP A;  1O4E A;  3IMJ A;  3VS2 A;  1AYB A;  1BLK A;  3BUX B;  2HCK A;  1JYQ A;  2C0I A;  3QWX X;  1B47 A;  5J3X A;  3UF4 A;  1SHD A;  1FBV A;  1G83 A;  1O4R A;  1NRV A;  1A09 A;  1LUK A;  1O47 A;  1O48 A;  1OO4 A;  3PQZ A;  4M4Z A;  1O4K A;  2EKX A;  1BKM A;  1CJ1 A;  4QSY A;  1GHU A;  3NHN A;  4WWQ A;  4E68 A;  4H1O A;  1O4M A;  1KC2 A;  3MAZ A;  2QMS A;  2CIA A;  1OPK A;  1H9O A;  2HDV A;  2Y1M A;  1NZL A;  3QWY A;  2PNB A;  4FBN A;  2KNO A;  1O4O A;  4K44 A;  2PTK A;  2VIF A;  5HKW A;  1FYR A;  1X6C A;  5KAZ A;  1AB2 A;  1CSZ A;  1BMB A;  2EYV A;  2LCT A;  3ZNI A;  1FU6 A;  1SPS A;  1K9A A;  1YVH A;  4GL9 E;  2ABL A;  1FU5 A;  4FL2 A;  4ROJ A;  5CDW A;  1AYD A;  3HIZ B;  2ETZ A;  5DC0 B;  2ECD A;  4XZ1 A;  3K2M A;  2H5K A;  3TKZ A;  1D1Z A;  1O42 A;  2XP1 A;  4OHI A;  1A1B A;  1KA7 A;  1SHB A;  1M61 A;  1CWE A;  3OB2 B;  1X27 A;  1R1Q A;  1LCJ A;  5GJH A;  1SHA A;  2C0T A;  5DC4 A;  2HMH A;  1FMK A;  3VRR A;  4A4B A;  4NWG A;  3VS6 A;  1BHF A;  2EL8 A;  3S8O A;  2DCR A;  2CR4 A;  3IN8 A;  4EIH A;  5EG3 B;  2HUW A;  3VS1 A;  4DGX A;  3BUN B;  3PS5 A;  1QAD A;  5EEL A;  2RMX A;  2H46 E;  1FBZ A;  2C0O A;  1OO3 A;  1A1E A;  3CD3 A;  2SRC A;  2MQI A;  1HCS B;  2CBL A;  2EO3 A;  4OHD A;  4K45 A;  1LUI A;  5EEQ A;  3M7F A;  3S8N A;  5IBM A;  3MXC A;  3CBL A;  5I6V A;  1NZV A;  3IN7 A;  2AUG A;  1SKJ A;  1CWD L;  1D4T A;  2FO0 A;  4GPL B;  4JE4 A;  1AOT F;  1BHH A;  3UYO A;  1O4C A;  1AYC A;  3HHM B;  2LQW A;  4DGP A;  3EAC A;  3PJP A;  4K11 A;  4F5A A;  2LQN A;  1YVL A;  5EHP A;  3S8L A;  1CSY A;  4K2R A;  3GXX A;  2EO6 A;  1M27 A;  1OPL A;  1BFJ A;  1O4L A;  3N8M A; 
#chains in the Genus database with same CATH topology
 2FCI A;  1JYR A;  2LNX A;  1O4D A;  1LCK A;  2KK6 A;  1O4Q A;  1O4I A;  1WQU A;  3BUM B;  2PNA A;  1F2F A;  1TCE A;  2AOB A;  2DX0 A;  2AOA A;  1BFI A;  1KA6 A;  1I3Z A;  3BKB A;  1BF5 A;  4L1B B;  3PLF B;  1O44 A;  3BUW B;  1BG1 A;  2MRK A;  1R1P A;  4LUD A;  4P9Z A;  5GJI A;  4U17 A;  2OZO A;  3OV1 A;  1LUN A;  3HCK A;  3US4 A;  5HKZ A;  1LKL A;  1P13 A;  3VGO A;  2CI8 A;  2MC1 A;  4NWF A;  1RPY A;  4X6S A;  1A1C A;  1QG1 E;  4EY0 A;  1AOU F;  1RQQ C;  2C9W A;  4H34 A;  2JYQ A;  2DLZ A;  2MK2 A;  1BLJ A;  3VRZ A;  3N84 A;  1O4H A;  3VS0 A;  3CXL A;  1D4W A;  2K79 B;  3VS7 A;  3GQI B;  1ZFP E;  1Y57 A;  5HKY A;  2LNW A;  2EOB A;  3PSK A;  1MW4 A;  4JEG A;  1JWO A;  4OHE A;  4LUE A;  2CS0 A;  4A4C A;  1O4N A;  2BBU A;  2HDX A;  1LUM A;  3KFJ A;  5DC9 A;  3VRN A;  2IUI A;  2ROR A;  3VS5 A;  4E93 A;  1UUR A;  3PFV A;  1KSW A;  1BHH B;  1O4P A;  2H8H A;  2L6K A;  2DLY A;  4OHL A;  2EYY A;  2PLD A;  2IUH A;  3GXW A;  3WA4 A;  1X0N A;  3N7Y A;  3MXY A;  1O4F A;  1IJR A;  2YSX A;  4F59 A;  5D0J A;  3PSJ A;  1BKL A;  1RJA A;  2GSB A;  2EYZ A;  1LKK A;  3OVE A;  4JGH A;  1AYA A;  1A07 A;  3VS4 A;  1MIL A;  2B3O A;  2MRJ A;  1R1S A;  2GE9 A;  1JYU A;  1A81 A;  1A08 A;  1O43 A;  3VRY A;  2RVF A;  2KGY A;  1SPR A;  2RSY A;  1FHS A;  1JU5 A;  2YU7 A;  2PLE A;  3OB1 B;  1QCF A;  4XZ0 A;  3T04 A;  3TL0 A;  1Z3K A;  2DVJ A;  1O4B A;  2Y1N A;  4P9V A;  4OHH A;  4F5B A;  1O41 A;  1O45 A;  2OQ1 A;  1BM2 A;  1A1A A;  2EU0 A;  2CI9 A;  1F1W A;  3OP0 A;  4D8K A;  3EAZ A;  2CRH A;  1AD5 A;  1UUS A;  1O4A A;  1XA6 A;  3LYV A;  3CWG A;  3VRQ A;  5AXI A;  2Y3A B;  1O4G A;  2IUG A;  1IS0 A;  2L4K A;  1O46 A;  1Y1U A;  1O4J A;  1TZE E;  5AUL A;  5DF6 A;  1O49 A;  3C7I A;  3VRP A;  3S9K A;  2K7A B;  1GRI A;  3IMD A;  2L3T A;  3VRO A;  4U1P A;  1PIC A;  4TZI A;  2IZV A;  2DM0 A;  5EHR A;  3BUO B;  5BO4 A;  3VS3 A;  4GWF A;  4FL3 A;  5IBS A;  1HCT B;  2SHP A;  1O4E A;  3IMJ A;  3VS2 A;  1AYB A;  1BLK A;  3BUX B;  2HCK A;  1JYQ A;  2C0I A;  3QWX X;  1B47 A;  5J3X A;  3UF4 A;  1SHD A;  1FBV A;  1G83 A;  1O4R A;  1NRV A;  1A09 A;  1LUK A;  1O47 A;  1O48 A;  1OO4 A;  3PQZ A;  4M4Z A;  1O4K A;  2EKX A;  1BKM A;  1CJ1 A;  4QSY A;  1GHU A;  3NHN A;  4WWQ A;  4E68 A;  4H1O A;  1O4M A;  1KC2 A;  3MAZ A;  2QMS A;  2CIA A;  1OPK A;  1H9O A;  2HDV A;  2Y1M A;  1NZL A;  3QWY A;  2PNB A;  4FBN A;  2KNO A;  1O4O A;  4K44 A;  2PTK A;  2VIF A;  5HKW A;  1FYR A;  1X6C A;  5KAZ A;  1AB2 A;  1CSZ A;  1BMB A;  2EYV A;  2LCT A;  3ZNI A;  1FU6 A;  1SPS A;  1K9A A;  1YVH A;  4GL9 E;  2LRA A;  2ABL A;  1FU5 A;  4FL2 A;  4ROJ A;  5CDW A;  1AYD A;  3HIZ B;  2ETZ A;  5DC0 B;  2ECD A;  4XZ1 A;  3K2M A;  2H5K A;  3TKZ A;  1D1Z A;  1O42 A;  2XP1 A;  4OHI A;  1A1B A;  1KA7 A;  1SHB A;  1M61 A;  1CWE A;  3OB2 B;  1X27 A;  1R1Q A;  1LCJ A;  5GJH A;  1SHA A;  2C0T A;  5DC4 A;  2HMH A;  1FMK A;  3VRR A;  4A4B A;  4NWG A;  3VS6 A;  1BHF A;  2EL8 A;  3S8O A;  2DCR A;  2CR4 A;  3IN8 A;  4EIH A;  5EG3 B;  2HUW A;  3VS1 A;  4DGX A;  3BUN B;  3PS5 A;  1QAD A;  5EEL A;  2RMX A;  2H46 E;  1FBZ A;  2C0O A;  1OO3 A;  1A1E A;  3CD3 A;  2SRC A;  2MQI A;  1HCS B;  2CBL A;  2EO3 A;  4OHD A;  4K45 A;  1LUI A;  5EEQ A;  3M7F A;  3S8N A;  5IBM A;  3MXC A;  3CBL A;  5I6V A;  1NZV A;  3IN7 A;  2AUG A;  1SKJ A;  3K2T A;  1CWD L;  1D4T A;  2FO0 A;  4GPL B;  4JE4 A;  1AOT F;  1BHH A;  3UYO A;  1O4C A;  1AYC A;  3HHM B;  2LQW A;  4DGP A;  3EAC A;  3PJP A;  4K11 A;  4F5A A;  2LQN A;  1YVL A;  5EHP A;  3S8L A;  1CSY A;  4K2R A;  3GXX A;  2EO6 A;  1M27 A;  1OPL A;  1BFJ A;  1O4L A;  3N8M A; 
#chains in the Genus database with same CATH homology
 2FCI A;  1JYR A;  2LNX A;  1O4D A;  1LCK A;  2KK6 A;  1O4Q A;  1O4I A;  1WQU A;  3BUM B;  2PNA A;  1F2F A;  1TCE A;  2AOB A;  2DX0 A;  2AOA A;  1BFI A;  1KA6 A;  1I3Z A;  3BKB A;  1BF5 A;  4L1B B;  3PLF B;  1O44 A;  3BUW B;  1BG1 A;  2MRK A;  1R1P A;  4LUD A;  4P9Z A;  5GJI A;  4U17 A;  2OZO A;  3OV1 A;  1LUN A;  3HCK A;  3US4 A;  5HKZ A;  1LKL A;  1P13 A;  3VGO A;  2CI8 A;  2MC1 A;  4NWF A;  1RPY A;  4X6S A;  1A1C A;  1QG1 E;  4EY0 A;  1AOU F;  1RQQ C;  2C9W A;  4H34 A;  2JYQ A;  2DLZ A;  2MK2 A;  1BLJ A;  3VRZ A;  3N84 A;  1O4H A;  3VS0 A;  3CXL A;  1D4W A;  2K79 B;  3VS7 A;  3GQI B;  1ZFP E;  1Y57 A;  5HKY A;  2LNW A;  2EOB A;  3PSK A;  1MW4 A;  4JEG A;  1JWO A;  4OHE A;  4LUE A;  2CS0 A;  4A4C A;  1O4N A;  2BBU A;  2HDX A;  1LUM A;  3KFJ A;  5DC9 A;  3VRN A;  2IUI A;  2ROR A;  3VS5 A;  4E93 A;  1UUR A;  3PFV A;  1KSW A;  1BHH B;  1O4P A;  2H8H A;  2L6K A;  2DLY A;  4OHL A;  2EYY A;  2PLD A;  2IUH A;  3GXW A;  3WA4 A;  1X0N A;  3N7Y A;  3MXY A;  1O4F A;  1IJR A;  2YSX A;  4F59 A;  5D0J A;  3PSJ A;  1BKL A;  1RJA A;  2GSB A;  2EYZ A;  1LKK A;  3OVE A;  4JGH A;  1AYA A;  1A07 A;  3VS4 A;  1MIL A;  2B3O A;  2MRJ A;  1R1S A;  2GE9 A;  1JYU A;  1A81 A;  1A08 A;  1O43 A;  3VRY A;  2RVF A;  1SPR A;  2RSY A;  1FHS A;  1JU5 A;  2YU7 A;  2PLE A;  3OB1 B;  1QCF A;  4XZ0 A;  3T04 A;  3TL0 A;  1Z3K A;  2DVJ A;  1O4B A;  2Y1N A;  4P9V A;  4OHH A;  4F5B A;  1O41 A;  1O45 A;  2OQ1 A;  1BM2 A;  1A1A A;  2EU0 A;  2CI9 A;  1F1W A;  3OP0 A;  4D8K A;  3EAZ A;  2CRH A;  1AD5 A;  1UUS A;  1O4A A;  1XA6 A;  3CWG A;  3VRQ A;  5AXI A;  2Y3A B;  1O4G A;  2IUG A;  1IS0 A;  2L4K A;  1O46 A;  1Y1U A;  1O4J A;  1TZE E;  5AUL A;  5DF6 A;  1O49 A;  3C7I A;  3VRP A;  3S9K A;  2K7A B;  1GRI A;  3IMD A;  2L3T A;  3VRO A;  4U1P A;  1PIC A;  4TZI A;  2IZV A;  2DM0 A;  5EHR A;  3BUO B;  5BO4 A;  3VS3 A;  4GWF A;  4FL3 A;  5IBS A;  1HCT B;  2SHP A;  1O4E A;  3IMJ A;  3VS2 A;  1AYB A;  1BLK A;  3BUX B;  2HCK A;  1JYQ A;  2C0I A;  3QWX X;  1B47 A;  5J3X A;  3UF4 A;  1SHD A;  1FBV A;  1G83 A;  1O4R A;  1NRV A;  1A09 A;  1LUK A;  1O47 A;  1O48 A;  1OO4 A;  3PQZ A;  4M4Z A;  1O4K A;  2EKX A;  1BKM A;  1CJ1 A;  4QSY A;  1GHU A;  3NHN A;  4WWQ A;  4E68 A;  4H1O A;  1O4M A;  1KC2 A;  3MAZ A;  2QMS A;  2CIA A;  1OPK A;  1H9O A;  2HDV A;  2Y1M A;  1NZL A;  3QWY A;  2PNB A;  4FBN A;  2KNO A;  1O4O A;  4K44 A;  2PTK A;  2VIF A;  5HKW A;  1FYR A;  1X6C A;  5KAZ A;  1AB2 A;  1CSZ A;  1BMB A;  2EYV A;  2LCT A;  3ZNI A;  1FU6 A;  1SPS A;  1K9A A;  1YVH A;  4GL9 E;  2ABL A;  1FU5 A;  4FL2 A;  4ROJ A;  5CDW A;  1AYD A;  3HIZ B;  2ETZ A;  5DC0 B;  2ECD A;  4XZ1 A;  3K2M A;  2H5K A;  3TKZ A;  1D1Z A;  1O42 A;  2XP1 A;  4OHI A;  1A1B A;  1KA7 A;  1SHB A;  1M61 A;  1CWE A;  3OB2 B;  1X27 A;  1R1Q A;  1LCJ A;  5GJH A;  1SHA A;  2C0T A;  5DC4 A;  2HMH A;  1FMK A;  3VRR A;  4A4B A;  4NWG A;  3VS6 A;  1BHF A;  2EL8 A;  3S8O A;  2DCR A;  2CR4 A;  3IN8 A;  4EIH A;  5EG3 B;  2HUW A;  3VS1 A;  4DGX A;  3BUN B;  3PS5 A;  1QAD A;  5EEL A;  2RMX A;  2H46 E;  1FBZ A;  2C0O A;  1OO3 A;  1A1E A;  3CD3 A;  2SRC A;  2MQI A;  1HCS B;  2CBL A;  2EO3 A;  4OHD A;  4K45 A;  1LUI A;  5EEQ A;  3M7F A;  3S8N A;  5IBM A;  3MXC A;  3CBL A;  5I6V A;  1NZV A;  3IN7 A;  2AUG A;  1SKJ A;  1CWD L;  1D4T A;  2FO0 A;  4GPL B;  4JE4 A;  1AOT F;  1BHH A;  3UYO A;  1O4C A;  1AYC A;  3HHM B;  2LQW A;  4DGP A;  3EAC A;  3PJP A;  4K11 A;  4F5A A;  2LQN A;  1YVL A;  5EHP A;  3S8L A;  1CSY A;  4K2R A;  3GXX A;  2EO6 A;  1M27 A;  1OPL A;  1BFJ A;  1O4L A;  3N8M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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