2IUIA

Crystal structure of the pi3-kinase p85 n-terminal sh2 domain in complex with pdgfr phosphotyrosyl peptide
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
107
structure length
107
Chain Sequence
MSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Phosphatidylinositol 3-kinase regulatory subunit alpha
total genus 29
structure length 107
sequence length 107
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2iuiA00
3HIZB 3OV1A 2GSBA 2EYYA 1R1QA 3VRYA 1MW4A 1I3ZA 1CWEA 5EELA 2PNBA 1FU6A 2OQ1A 1O4RA 1LKLA 1WQUA 4OHLA 1BG1A 3QWYA 1RJAA 1A08A 1OPLA 4M4ZA 3VS3A 2PLEA 5HKWA 3IN7A 5EHRA 2CI9A 3BUNB 3BUWB 4P9ZA 1HCSB 5EEQA 4FL3A 1GRIA 2LNWA 1UURA 1BFJA 3S9KA 3IMDA 1O4QA 3HHMB 4X6SA 1TZEE 1O4MA 1YVLA 2HCKA 4K45A 1X0NA 3US4A 3N8MA 1O4FA 2EYZA 4QSYA 1LKKA 4F5BA 1AOUF 4A4BA 3GXXA 2LNXA 1O4BA 2Y1NA 1ZFPE 2FO0A 1KA6A 1LUMA 1F1WA 2EU0A 3PQZA 1SHBA 3PFVA 5KAZA 2AUGA 1SHAA 1BLKA 3N7YA 2EKXA 2DM0A 1AOTF 2KK6A 1A1CA 2MK2A 3BUOB 3KFJA 3T04A 1BKLA 2OZOA 1TCEA 1M61A 2EL8A 4GL9E 4XZ0A 3TL0A 3VROA 3OP0A 2CR4A 2HDVA 2YU7A 1QCFA 1YVHA 1LUIA 3EACA 3VRQA 1BHHA 1BMBA 5HKYA 3VS6A 4GPLB 4LUDA 4NWGA 4H1OA 3PLFB 3VS7A 1AYAA 2EYVA 1O42A 3C7IA 3HCKA 1K9AA 3MXYA 5DF6A 1O4HA 2B3OA 3NHNA 3VS4A 2EOBA 1AYCA 1OO4A 1AD5A 1CJ1A 1O4PA 2IUHA 4U1PA 1GHUA 1CSYA 1LCKA 2CRHA 5DC0B 1FHSA 3EAZA 2PNAA 3IMJA 3MAZA 1O4DA 3TKZA 1IJRA 1LUKA 3OVEA 1B47A 5D0JA 1O49A 1UUSA 1O44A 3VRRA 1O41A 4JEGA 4P9VA 3VS1A 4GWFA 1R1SA 1FYRA 1LCJA 3PJPA 1KA7A 4OHDA 2XP1A 3CXLA 2CBLA 2PTKA 2HMHA 5IBMA 1OO3A 2IUGA 1Z3KA 3VS0A 4JGHA 3VRPA 4K11A 3CBLA 4A4CA 1LUNA 2C0IA 4LUEA 2CIAA 2VIFA 2H46E 2C0OA 1P13A 3PSJA 1AYDA 2ETZA 5EG3B 2ECDA 4OHEA 1A1EA 1O4IA 3BKBA 4K44A 1QADA 2JYQA 4U17A 1BF5A 2DVJA 4EY0A 2DCRA 1JYQA 2MRJA 1BLJA 2HUWA 1X27A 2RVFA 5EHPA 3VRNA 2LQWA 3OB2B 2PLDA 1BFIA 1O4JA 1NZLA 4NWFA 2MRKA 1Y1UA 2RMXA 5AXIA 1A09A 2CS0A 2HDXA 1A07A 2H8HA 1AB2A 2FCIA 1G83A 1O43A 2DX0A 2L4KA 1O4LA 3M7FA 2DLZA 1QG1E 2CI8A 4D8KA 1NZVA 2MC1A 2EO3A 1A1AA 2RORA 3OB1B 1JYUA 1CWDL 3CD3A 1MILA 2ABLA 1OPKA 1BHHB 5DC9A 1O45A 5IBSA 1O4OA 5HKZA 3S8LA 1O4NA 3PS5A 2C0TA 2H5KA 4OHIA 1FU5A 3IN8A 3BUXB 2K7AB 3UF4A 4FBNA 4EIHA 5GJIA 4ROJA 1RQQC 1O47A 1BKMA 1NRVA 1O4GA 2AOBA 5DC4A 1O4EA 2IUIA 1SHDA 1BM2A 1BHFA 2K79B 4H34A 4F5AA 3WA4A 3S8OA 1AYBA 2L6KA 3VS2A 1R1PA 3VRZA 4OHHA 1JYRA 1RPYA 1D1ZA 1CSZA 2GE9A 1FMKA 2Y1MA 1O46A 2SHPA 4E68A 1O48A 1H9OA 1A1BA 3UYOA 2SRCA 2C9WA 3CWGA 2LQNA 3GXWA 1KC2A 3QWXX 1O4KA 1FBVA 1KSWA 2IZVA 2QMSA 2RSYA 2L3TA 2YSXA 4FL2A 5GJHA 3VGOA 3ZNIA 4JE4A 3VS5A 5BO4A 3MXCA 4E93A 1PICA 1X6CA 1F2FA 4TZIA 4K2RA 1XA6A 2MQIA 4XZ1A 1FBZA 3BUMB 3N84A 5AULA 4DGPA 1D4TA 3GQIB 2KNOA 5J3XA 1SKJA 2LCTA 1M27A 3PSKA 4F59A 4DGXA 5I6VA 2AOAA 1SPSA 4WWQA 2BBUA 1SPRA 1D4WA 2Y3AB 1O4CA 4L1BB 3S8NA 5CDWA 1O4AA 1JU5A 2DLYA 1IS0A 3K2MA 1Y57A 2EO6A 1A81A 1JWOA 1HCTB
chains in the Genus database with same CATH superfamily
3HIZB 3OV1A 2GSBA 2EYYA 1R1QA 3VRYA 1MW4A 1I3ZA 1CWEA 5EELA 2PNBA 1FU6A 2OQ1A 1O4RA 1LKLA 1WQUA 4OHLA 1BG1A 3QWYA 1RJAA 1A08A 1OPLA 4M4ZA 3VS3A 2PLEA 5HKWA 3IN7A 5EHRA 2CI9A 3BUNB 3BUWB 4P9ZA 1HCSB 5EEQA 4FL3A 1GRIA 2LNWA 1UURA 1BFJA 3S9KA 3IMDA 1O4QA 3HHMB 4X6SA 1TZEE 1O4MA 1YVLA 2HCKA 4K45A 1X0NA 3US4A 3N8MA 1O4FA 2EYZA 4QSYA 1LKKA 4F5BA 1AOUF 4A4BA 3GXXA 2LNXA 1O4BA 2Y1NA 1ZFPE 2FO0A 1KA6A 1LUMA 1F1WA 2EU0A 3PQZA 1SHBA 3PFVA 5KAZA 2AUGA 1SHAA 1BLKA 3N7YA 2EKXA 2DM0A 1AOTF 2KK6A 1A1CA 2MK2A 3BUOB 3KFJA 3T04A 1BKLA 2OZOA 1TCEA 1M61A 2EL8A 4GL9E 4XZ0A 3TL0A 3VROA 3OP0A 2CR4A 2HDVA 2YU7A 1QCFA 1YVHA 1LUIA 3EACA 3VRQA 1BHHA 1BMBA 5HKYA 3VS6A 4GPLB 4LUDA 4NWGA 4H1OA 3PLFB 3VS7A 1AYAA 2EYVA 1O42A 3C7IA 3HCKA 1K9AA 3MXYA 5DF6A 1O4HA 2B3OA 3NHNA 3VS4A 2EOBA 1AYCA 1OO4A 1AD5A 1CJ1A 1O4PA 2IUHA 4U1PA 1GHUA 1CSYA 1LCKA 2CRHA 5DC0B 1FHSA 3EAZA 2PNAA 3IMJA 3MAZA 1O4DA 3TKZA 1IJRA 1LUKA 3OVEA 1B47A 5D0JA 1O49A 1UUSA 1O44A 3VRRA 1O41A 4JEGA 4P9VA 3VS1A 4GWFA 1R1SA 1FYRA 1LCJA 3PJPA 1KA7A 4OHDA 2XP1A 3CXLA 2CBLA 2PTKA 2HMHA 5IBMA 1OO3A 2IUGA 1Z3KA 3VS0A 4JGHA 3VRPA 4K11A 3CBLA 4A4CA 1LUNA 2C0IA 4LUEA 2KGYA 2CIAA 2VIFA 2H46E 2C0OA 1P13A 3PSJA 1AYDA 2ETZA 5EG3B 2ECDA 4OHEA 1A1EA 1O4IA 3BKBA 4K44A 1QADA 2JYQA 4U17A 1BF5A 2DVJA 4EY0A 2DCRA 1JYQA 2MRJA 1BLJA 2HUWA 1X27A 2RVFA 5EHPA 3VRNA 2LQWA 3OB2B 2PLDA 1BFIA 1O4JA 1NZLA 4NWFA 2MRKA 1Y1UA 2RMXA 5AXIA 1A09A 2CS0A 2HDXA 1A07A 2H8HA 1AB2A 2LRAA 2FCIA 1G83A 1O43A 2DX0A 2L4KA 1O4LA 3M7FA 2DLZA 1QG1E 2CI8A 4D8KA 1NZVA 2MC1A 2EO3A 1A1AA 2RORA 3OB1B 1JYUA 1CWDL 3CD3A 1MILA 2ABLA 1OPKA 1BHHB 5DC9A 1O45A 5IBSA 1O4OA 5HKZA 3S8LA 1O4NA 3PS5A 2C0TA 2H5KA 4OHIA 1FU5A 3IN8A 3BUXB 2K7AB 3UF4A 4FBNA 4EIHA 5GJIA 4ROJA 1RQQC 1O47A 1BKMA 1NRVA 1O4GA 2AOBA 5DC4A 1O4EA 2IUIA 1SHDA 1BM2A 1BHFA 2K79B 4H34A 4F5AA 3WA4A 3S8OA 1AYBA 2L6KA 3VS2A 1R1PA 3VRZA 4OHHA 1JYRA 1RPYA 1D1ZA 1CSZA 2GE9A 1FMKA 2Y1MA 1O46A 2SHPA 4E68A 1O48A 1H9OA 1A1BA 3UYOA 2SRCA 2C9WA 3CWGA 2LQNA 3GXWA 1KC2A 3QWXX 1O4KA 1FBVA 1KSWA 2IZVA 2QMSA 2RSYA 2L3TA 2YSXA 4FL2A 5GJHA 3VGOA 3ZNIA 4JE4A 3VS5A 5BO4A 3MXCA 4E93A 1PICA 1X6CA 1F2FA 4TZIA 4K2RA 1XA6A 2MQIA 4XZ1A 1FBZA 3BUMB 3N84A 3K2TA 5AULA 4DGPA 1D4TA 3GQIB 2KNOA 5J3XA 1SKJA 2LCTA 1M27A 3PSKA 4F59A 4DGXA 5I6VA 2AOAA 1SPSA 4WWQA 2BBUA 1SPRA 1D4WA 2Y3AB 1O4CA 4L1BB 3LYVA 3S8NA 5CDWA 1O4AA 1JU5A 2DLYA 1IS0A 3K2MA 1Y57A 2EO6A 1A81A 1JWOA 1HCTB
chains in the Genus database with same CATH topology
3HIZB 3OV1A 2GSBA 2EYYA 1R1QA 3VRYA 1MW4A 1I3ZA 1CWEA 5EELA 2PNBA 1FU6A 2OQ1A 1O4RA 1LKLA 1WQUA 4OHLA 1BG1A 3QWYA 1RJAA 1A08A 1OPLA 4M4ZA 3VS3A 2PLEA 5HKWA 3IN7A 5EHRA 2CI9A 3BUNB 3BUWB 4P9ZA 1HCSB 5EEQA 4FL3A 1GRIA 2LNWA 1UURA 1BFJA 3S9KA 3IMDA 1O4QA 3HHMB 4X6SA 1TZEE 1O4MA 1YVLA 2HCKA 4K45A 1X0NA 3US4A 3N8MA 1O4FA 2EYZA 4QSYA 1LKKA 4F5BA 1AOUF 4A4BA 3GXXA 2LNXA 1O4BA 2Y1NA 1ZFPE 2FO0A 1KA6A 1LUMA 1F1WA 2EU0A 3PQZA 1SHBA 3PFVA 5KAZA 2AUGA 1SHAA 1BLKA 3N7YA 2EKXA 2DM0A 1AOTF 2KK6A 1A1CA 2MK2A 3BUOB 3KFJA 3T04A 1BKLA 2OZOA 1TCEA 1M61A 2EL8A 4GL9E 4XZ0A 3TL0A 3VROA 3OP0A 2CR4A 2HDVA 2YU7A 1QCFA 1YVHA 1LUIA 3EACA 3VRQA 1BHHA 1BMBA 5HKYA 3VS6A 4GPLB 4LUDA 4NWGA 4H1OA 3PLFB 3VS7A 1AYAA 2EYVA 1O42A 3C7IA 3HCKA 1K9AA 3MXYA 5DF6A 1O4HA 2B3OA 3NHNA 3VS4A 2EOBA 1AYCA 1OO4A 1AD5A 1CJ1A 1O4PA 2IUHA 4U1PA 1GHUA 1CSYA 1LCKA 2CRHA 5DC0B 1FHSA 3EAZA 2PNAA 3IMJA 3MAZA 1O4DA 3TKZA 1IJRA 1LUKA 3OVEA 1B47A 5D0JA 1O49A 1UUSA 1O44A 3VRRA 1O41A 4JEGA 4P9VA 3VS1A 4GWFA 1R1SA 1FYRA 1LCJA 3PJPA 1KA7A 4OHDA 2XP1A 3CXLA 2CBLA 2PTKA 2HMHA 5IBMA 1OO3A 2IUGA 1Z3KA 3VS0A 4JGHA 3VRPA 4K11A 3CBLA 4A4CA 1LUNA 2C0IA 4LUEA 2CIAA 2VIFA 2H46E 2C0OA 1P13A 3PSJA 1AYDA 2ETZA 5EG3B 2ECDA 4OHEA 1A1EA 1O4IA 3BKBA 4K44A 1QADA 2JYQA 4U17A 1BF5A 2DVJA 4EY0A 2DCRA 1JYQA 2MRJA 1BLJA 2HUWA 1X27A 2RVFA 5EHPA 3VRNA 2LQWA 3OB2B 2PLDA 1BFIA 1O4JA 1NZLA 4NWFA 2MRKA 1Y1UA 2RMXA 5AXIA 1A09A 2CS0A 2HDXA 1A07A 2H8HA 1AB2A 2FCIA 1G83A 1O43A 2DX0A 2L4KA 1O4LA 3M7FA 2DLZA 1QG1E 2CI8A 4D8KA 1NZVA 2MC1A 2EO3A 1A1AA 2RORA 3OB1B 1JYUA 1CWDL 3CD3A 1MILA 2ABLA 1OPKA 1BHHB 5DC9A 1O45A 5IBSA 1O4OA 5HKZA 3S8LA 1O4NA 3PS5A 2C0TA 2H5KA 4OHIA 1FU5A 3IN8A 3BUXB 2K7AB 3UF4A 4FBNA 4EIHA 5GJIA 4ROJA 1RQQC 1O47A 1BKMA 1NRVA 1O4GA 2AOBA 5DC4A 1O4EA 2IUIA 1SHDA 1BM2A 1BHFA 2K79B 4H34A 4F5AA 3WA4A 3S8OA 1AYBA 2L6KA 3VS2A 1R1PA 3VRZA 4OHHA 1JYRA 1RPYA 1D1ZA 1CSZA 2GE9A 1FMKA 2Y1MA 1O46A 2SHPA 4E68A 1O48A 1H9OA 1A1BA 3UYOA 2SRCA 2C9WA 3CWGA 2LQNA 3GXWA 1KC2A 3QWXX 1O4KA 1FBVA 1KSWA 2IZVA 2QMSA 2RSYA 2L3TA 2YSXA 4FL2A 5GJHA 3VGOA 3ZNIA 4JE4A 3VS5A 5BO4A 3MXCA 4E93A 1PICA 1X6CA 1F2FA 4TZIA 4K2RA 1XA6A 2MQIA 4XZ1A 1FBZA 3BUMB 3N84A 5AULA 4DGPA 1D4TA 3GQIB 2KNOA 5J3XA 1SKJA 2LCTA 1M27A 3PSKA 4F59A 4DGXA 5I6VA 2AOAA 1SPSA 4WWQA 2BBUA 1SPRA 1D4WA 2Y3AB 1O4CA 4L1BB 3S8NA 5CDWA 1O4AA 1JU5A 2DLYA 1IS0A 3K2MA 1Y57A 2EO6A 1A81A 1JWOA 1HCTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HIZ B;  3OV1 A;  2GSB A;  2EYY A;  1R1Q A;  3VRY A;  1MW4 A;  1I3Z A;  1CWE A;  5EEL A;  2PNB A;  1FU6 A;  2OQ1 A;  1O4R A;  1LKL A;  1WQU A;  4OHL A;  1BG1 A;  3QWY A;  1RJA A;  1A08 A;  1OPL A;  4M4Z A;  3VS3 A;  2PLE A;  5HKW A;  3IN7 A;  5EHR A;  2CI9 A;  3BUN B;  3BUW B;  4P9Z A;  1HCS B;  5EEQ A;  4FL3 A;  1GRI A;  2LNW A;  1UUR A;  1BFJ A;  3S9K A;  3IMD A;  1O4Q A;  3HHM B;  4X6S A;  1TZE E;  1O4M A;  1YVL A;  2HCK A;  4K45 A;  1X0N A;  3US4 A;  3N8M A;  1O4F A;  2EYZ A;  4QSY A;  1LKK A;  4F5B A;  1AOU F;  4A4B A;  3GXX A;  2LNX A;  1O4B A;  2Y1N A;  1ZFP E;  2FO0 A;  1KA6 A;  1LUM A;  1F1W A;  2EU0 A;  3PQZ A;  1SHB A;  3PFV A;  5KAZ A;  2AUG A;  1SHA A;  1BLK A;  3N7Y A;  2EKX A;  2DM0 A;  1AOT F;  2KK6 A;  1A1C A;  2MK2 A;  3BUO B;  3KFJ A;  3T04 A;  1BKL A;  2OZO A;  1TCE A;  1M61 A;  2EL8 A;  4GL9 E;  4XZ0 A;  3TL0 A;  3VRO A;  3OP0 A;  2CR4 A;  2HDV A;  2YU7 A;  1QCF A;  1YVH A;  1LUI A;  3EAC A;  3VRQ A;  1BHH A;  1BMB A;  5HKY A;  3VS6 A;  4GPL B;  4LUD A;  4NWG A;  4H1O A;  3PLF B;  3VS7 A;  1AYA A;  2EYV A;  1O42 A;  3C7I A;  3HCK A;  1K9A A;  3MXY A;  5DF6 A;  1O4H A;  2B3O A;  3NHN A;  3VS4 A;  2EOB A;  1AYC A;  1OO4 A;  1AD5 A;  1CJ1 A;  1O4P A;  2IUH A;  4U1P A;  1GHU A;  1CSY A;  1LCK A;  2CRH A;  5DC0 B;  1FHS A;  3EAZ A;  2PNA A;  3IMJ A;  3MAZ A;  1O4D A;  3TKZ A;  1IJR A;  1LUK A;  3OVE A;  1B47 A;  5D0J A;  1O49 A;  1UUS A;  1O44 A;  3VRR A;  1O41 A;  4JEG A;  4P9V A;  3VS1 A;  4GWF A;  1R1S A;  1FYR A;  1LCJ A;  3PJP A;  1KA7 A;  4OHD A;  2XP1 A;  3CXL A;  2CBL A;  2PTK A;  2HMH A;  5IBM A;  1OO3 A;  2IUG A;  1Z3K A;  3VS0 A;  4JGH A;  3VRP A;  4K11 A;  3CBL A;  4A4C A;  1LUN A;  2C0I A;  4LUE A;  2CIA A;  2VIF A;  2H46 E;  2C0O A;  1P13 A;  3PSJ A;  1AYD A;  2ETZ A;  5EG3 B;  2ECD A;  4OHE A;  1A1E A;  1O4I A;  3BKB A;  4K44 A;  1QAD A;  2JYQ A;  4U17 A;  1BF5 A;  2DVJ A;  4EY0 A;  2DCR A;  1JYQ A;  2MRJ A;  1BLJ A;  2HUW A;  1X27 A;  2RVF A;  5EHP A;  3VRN A;  2LQW A;  3OB2 B;  2PLD A;  1BFI A;  1O4J A;  1NZL A;  4NWF A;  2MRK A;  1Y1U A;  2RMX A;  5AXI A;  1A09 A;  2CS0 A;  2HDX A;  1A07 A;  2H8H A;  1AB2 A;  2FCI A;  1G83 A;  1O43 A;  2DX0 A;  2L4K A;  1O4L A;  3M7F A;  2DLZ A;  1QG1 E;  2CI8 A;  4D8K A;  1NZV A;  2MC1 A;  2EO3 A;  1A1A A;  2ROR A;  3OB1 B;  1JYU A;  1CWD L;  3CD3 A;  1MIL A;  2ABL A;  1OPK A;  1BHH B;  5DC9 A;  1O45 A;  5IBS A;  1O4O A;  5HKZ A;  3S8L A;  1O4N A;  3PS5 A;  2C0T A;  2H5K A;  4OHI A;  1FU5 A;  3IN8 A;  3BUX B;  2K7A B;  3UF4 A;  4FBN A;  4EIH A;  5GJI A;  4ROJ A;  1RQQ C;  1O47 A;  1BKM A;  1NRV A;  1O4G A;  2AOB A;  5DC4 A;  1O4E A;  2IUI A;  1SHD A;  1BM2 A;  1BHF A;  2K79 B;  4H34 A;  4F5A A;  3WA4 A;  3S8O A;  1AYB A;  2L6K A;  3VS2 A;  1R1P A;  3VRZ A;  4OHH A;  1JYR A;  1RPY A;  1D1Z A;  1CSZ A;  2GE9 A;  1FMK A;  2Y1M A;  1O46 A;  2SHP A;  4E68 A;  1O48 A;  1H9O A;  1A1B A;  3UYO A;  2SRC A;  2C9W A;  3CWG A;  2LQN A;  3GXW A;  1KC2 A;  3QWX X;  1O4K A;  1FBV A;  1KSW A;  2IZV A;  2QMS A;  2RSY A;  2L3T A;  2YSX A;  4FL2 A;  5GJH A;  3VGO A;  3ZNI A;  4JE4 A;  3VS5 A;  5BO4 A;  3MXC A;  4E93 A;  1PIC A;  1X6C A;  1F2F A;  4TZI A;  4K2R A;  1XA6 A;  2MQI A;  4XZ1 A;  1FBZ A;  3BUM B;  3N84 A;  5AUL A;  4DGP A;  1D4T A;  3GQI B;  2KNO A;  5J3X A;  1SKJ A;  2LCT A;  1M27 A;  3PSK A;  4F59 A;  4DGX A;  5I6V A;  2AOA A;  1SPS A;  4WWQ A;  2BBU A;  1SPR A;  1D4W A;  2Y3A B;  1O4C A;  4L1B B;  3S8N A;  5CDW A;  1O4A A;  1JU5 A;  2DLY A;  1IS0 A;  3K2M A;  1Y57 A;  2EO6 A;  1A81 A;  1JWO A;  1HCT B; 
#chains in the Genus database with same CATH topology
 3HIZ B;  3OV1 A;  2GSB A;  2EYY A;  1R1Q A;  3VRY A;  1MW4 A;  1I3Z A;  1CWE A;  5EEL A;  2PNB A;  1FU6 A;  2OQ1 A;  1O4R A;  1LKL A;  1WQU A;  4OHL A;  1BG1 A;  3QWY A;  1RJA A;  1A08 A;  1OPL A;  4M4Z A;  3VS3 A;  2PLE A;  5HKW A;  3IN7 A;  5EHR A;  2CI9 A;  3BUN B;  3BUW B;  4P9Z A;  1HCS B;  5EEQ A;  4FL3 A;  1GRI A;  2LNW A;  1UUR A;  1BFJ A;  3S9K A;  3IMD A;  1O4Q A;  3HHM B;  4X6S A;  1TZE E;  1O4M A;  1YVL A;  2HCK A;  4K45 A;  1X0N A;  3US4 A;  3N8M A;  1O4F A;  2EYZ A;  4QSY A;  1LKK A;  4F5B A;  1AOU F;  4A4B A;  3GXX A;  2LNX A;  1O4B A;  2Y1N A;  1ZFP E;  2FO0 A;  1KA6 A;  1LUM A;  1F1W A;  2EU0 A;  3PQZ A;  1SHB A;  3PFV A;  5KAZ A;  2AUG A;  1SHA A;  1BLK A;  3N7Y A;  2EKX A;  2DM0 A;  1AOT F;  2KK6 A;  1A1C A;  2MK2 A;  3BUO B;  3KFJ A;  3T04 A;  1BKL A;  2OZO A;  1TCE A;  1M61 A;  2EL8 A;  4GL9 E;  4XZ0 A;  3TL0 A;  3VRO A;  3OP0 A;  2CR4 A;  2HDV A;  2YU7 A;  1QCF A;  1YVH A;  1LUI A;  3EAC A;  3VRQ A;  1BHH A;  1BMB A;  5HKY A;  3VS6 A;  4GPL B;  4LUD A;  4NWG A;  4H1O A;  3PLF B;  3VS7 A;  1AYA A;  2EYV A;  1O42 A;  3C7I A;  3HCK A;  1K9A A;  3MXY A;  5DF6 A;  1O4H A;  2B3O A;  3NHN A;  3VS4 A;  2EOB A;  1AYC A;  1OO4 A;  1AD5 A;  1CJ1 A;  1O4P A;  2IUH A;  4U1P A;  1GHU A;  1CSY A;  1LCK A;  2CRH A;  5DC0 B;  1FHS A;  3EAZ A;  2PNA A;  3IMJ A;  3MAZ A;  1O4D A;  3TKZ A;  1IJR A;  1LUK A;  3OVE A;  1B47 A;  5D0J A;  1O49 A;  1UUS A;  1O44 A;  3VRR A;  1O41 A;  4JEG A;  4P9V A;  3VS1 A;  4GWF A;  1R1S A;  1FYR A;  1LCJ A;  3PJP A;  1KA7 A;  4OHD A;  2XP1 A;  3CXL A;  2CBL A;  2PTK A;  2HMH A;  5IBM A;  1OO3 A;  2IUG A;  1Z3K A;  3VS0 A;  4JGH A;  3VRP A;  4K11 A;  3CBL A;  4A4C A;  1LUN A;  2C0I A;  4LUE A;  2KGY A;  2CIA A;  2VIF A;  2H46 E;  2C0O A;  1P13 A;  3PSJ A;  1AYD A;  2ETZ A;  5EG3 B;  2ECD A;  4OHE A;  1A1E A;  1O4I A;  3BKB A;  4K44 A;  1QAD A;  2JYQ A;  4U17 A;  1BF5 A;  2DVJ A;  4EY0 A;  2DCR A;  1JYQ A;  2MRJ A;  1BLJ A;  2HUW A;  1X27 A;  2RVF A;  5EHP A;  3VRN A;  2LQW A;  3OB2 B;  2PLD A;  1BFI A;  1O4J A;  1NZL A;  4NWF A;  2MRK A;  1Y1U A;  2RMX A;  5AXI A;  1A09 A;  2CS0 A;  2HDX A;  1A07 A;  2H8H A;  1AB2 A;  2LRA A;  2FCI A;  1G83 A;  1O43 A;  2DX0 A;  2L4K A;  1O4L A;  3M7F A;  2DLZ A;  1QG1 E;  2CI8 A;  4D8K A;  1NZV A;  2MC1 A;  2EO3 A;  1A1A A;  2ROR A;  3OB1 B;  1JYU A;  1CWD L;  3CD3 A;  1MIL A;  2ABL A;  1OPK A;  1BHH B;  5DC9 A;  1O45 A;  5IBS A;  1O4O A;  5HKZ A;  3S8L A;  1O4N A;  3PS5 A;  2C0T A;  2H5K A;  4OHI A;  1FU5 A;  3IN8 A;  3BUX B;  2K7A B;  3UF4 A;  4FBN A;  4EIH A;  5GJI A;  4ROJ A;  1RQQ C;  1O47 A;  1BKM A;  1NRV A;  1O4G A;  2AOB A;  5DC4 A;  1O4E A;  2IUI A;  1SHD A;  1BM2 A;  1BHF A;  2K79 B;  4H34 A;  4F5A A;  3WA4 A;  3S8O A;  1AYB A;  2L6K A;  3VS2 A;  1R1P A;  3VRZ A;  4OHH A;  1JYR A;  1RPY A;  1D1Z A;  1CSZ A;  2GE9 A;  1FMK A;  2Y1M A;  1O46 A;  2SHP A;  4E68 A;  1O48 A;  1H9O A;  1A1B A;  3UYO A;  2SRC A;  2C9W A;  3CWG A;  2LQN A;  3GXW A;  1KC2 A;  3QWX X;  1O4K A;  1FBV A;  1KSW A;  2IZV A;  2QMS A;  2RSY A;  2L3T A;  2YSX A;  4FL2 A;  5GJH A;  3VGO A;  3ZNI A;  4JE4 A;  3VS5 A;  5BO4 A;  3MXC A;  4E93 A;  1PIC A;  1X6C A;  1F2F A;  4TZI A;  4K2R A;  1XA6 A;  2MQI A;  4XZ1 A;  1FBZ A;  3BUM B;  3N84 A;  3K2T A;  5AUL A;  4DGP A;  1D4T A;  3GQI B;  2KNO A;  5J3X A;  1SKJ A;  2LCT A;  1M27 A;  3PSK A;  4F59 A;  4DGX A;  5I6V A;  2AOA A;  1SPS A;  4WWQ A;  2BBU A;  1SPR A;  1D4W A;  2Y3A B;  1O4C A;  4L1B B;  3LYV A;  3S8N A;  5CDW A;  1O4A A;  1JU5 A;  2DLY A;  1IS0 A;  3K2M A;  1Y57 A;  2EO6 A;  1A81 A;  1JWO A;  1HCT B; 
#chains in the Genus database with same CATH homology
 3HIZ B;  3OV1 A;  2GSB A;  2EYY A;  1R1Q A;  3VRY A;  1MW4 A;  1I3Z A;  1CWE A;  5EEL A;  2PNB A;  1FU6 A;  2OQ1 A;  1O4R A;  1LKL A;  1WQU A;  4OHL A;  1BG1 A;  3QWY A;  1RJA A;  1A08 A;  1OPL A;  4M4Z A;  3VS3 A;  2PLE A;  5HKW A;  3IN7 A;  5EHR A;  2CI9 A;  3BUN B;  3BUW B;  4P9Z A;  1HCS B;  5EEQ A;  4FL3 A;  1GRI A;  2LNW A;  1UUR A;  1BFJ A;  3S9K A;  3IMD A;  1O4Q A;  3HHM B;  4X6S A;  1TZE E;  1O4M A;  1YVL A;  2HCK A;  4K45 A;  1X0N A;  3US4 A;  3N8M A;  1O4F A;  2EYZ A;  4QSY A;  1LKK A;  4F5B A;  1AOU F;  4A4B A;  3GXX A;  2LNX A;  1O4B A;  2Y1N A;  1ZFP E;  2FO0 A;  1KA6 A;  1LUM A;  1F1W A;  2EU0 A;  3PQZ A;  1SHB A;  3PFV A;  5KAZ A;  2AUG A;  1SHA A;  1BLK A;  3N7Y A;  2EKX A;  2DM0 A;  1AOT F;  2KK6 A;  1A1C A;  2MK2 A;  3BUO B;  3KFJ A;  3T04 A;  1BKL A;  2OZO A;  1TCE A;  1M61 A;  2EL8 A;  4GL9 E;  4XZ0 A;  3TL0 A;  3VRO A;  3OP0 A;  2CR4 A;  2HDV A;  2YU7 A;  1QCF A;  1YVH A;  1LUI A;  3EAC A;  3VRQ A;  1BHH A;  1BMB A;  5HKY A;  3VS6 A;  4GPL B;  4LUD A;  4NWG A;  4H1O A;  3PLF B;  3VS7 A;  1AYA A;  2EYV A;  1O42 A;  3C7I A;  3HCK A;  1K9A A;  3MXY A;  5DF6 A;  1O4H A;  2B3O A;  3NHN A;  3VS4 A;  2EOB A;  1AYC A;  1OO4 A;  1AD5 A;  1CJ1 A;  1O4P A;  2IUH A;  4U1P A;  1GHU A;  1CSY A;  1LCK A;  2CRH A;  5DC0 B;  1FHS A;  3EAZ A;  2PNA A;  3IMJ A;  3MAZ A;  1O4D A;  3TKZ A;  1IJR A;  1LUK A;  3OVE A;  1B47 A;  5D0J A;  1O49 A;  1UUS A;  1O44 A;  3VRR A;  1O41 A;  4JEG A;  4P9V A;  3VS1 A;  4GWF A;  1R1S A;  1FYR A;  1LCJ A;  3PJP A;  1KA7 A;  4OHD A;  2XP1 A;  3CXL A;  2CBL A;  2PTK A;  2HMH A;  5IBM A;  1OO3 A;  2IUG A;  1Z3K A;  3VS0 A;  4JGH A;  3VRP A;  4K11 A;  3CBL A;  4A4C A;  1LUN A;  2C0I A;  4LUE A;  2CIA A;  2VIF A;  2H46 E;  2C0O A;  1P13 A;  3PSJ A;  1AYD A;  2ETZ A;  5EG3 B;  2ECD A;  4OHE A;  1A1E A;  1O4I A;  3BKB A;  4K44 A;  1QAD A;  2JYQ A;  4U17 A;  1BF5 A;  2DVJ A;  4EY0 A;  2DCR A;  1JYQ A;  2MRJ A;  1BLJ A;  2HUW A;  1X27 A;  2RVF A;  5EHP A;  3VRN A;  2LQW A;  3OB2 B;  2PLD A;  1BFI A;  1O4J A;  1NZL A;  4NWF A;  2MRK A;  1Y1U A;  2RMX A;  5AXI A;  1A09 A;  2CS0 A;  2HDX A;  1A07 A;  2H8H A;  1AB2 A;  2FCI A;  1G83 A;  1O43 A;  2DX0 A;  2L4K A;  1O4L A;  3M7F A;  2DLZ A;  1QG1 E;  2CI8 A;  4D8K A;  1NZV A;  2MC1 A;  2EO3 A;  1A1A A;  2ROR A;  3OB1 B;  1JYU A;  1CWD L;  3CD3 A;  1MIL A;  2ABL A;  1OPK A;  1BHH B;  5DC9 A;  1O45 A;  5IBS A;  1O4O A;  5HKZ A;  3S8L A;  1O4N A;  3PS5 A;  2C0T A;  2H5K A;  4OHI A;  1FU5 A;  3IN8 A;  3BUX B;  2K7A B;  3UF4 A;  4FBN A;  4EIH A;  5GJI A;  4ROJ A;  1RQQ C;  1O47 A;  1BKM A;  1NRV A;  1O4G A;  2AOB A;  5DC4 A;  1O4E A;  2IUI A;  1SHD A;  1BM2 A;  1BHF A;  2K79 B;  4H34 A;  4F5A A;  3WA4 A;  3S8O A;  1AYB A;  2L6K A;  3VS2 A;  1R1P A;  3VRZ A;  4OHH A;  1JYR A;  1RPY A;  1D1Z A;  1CSZ A;  2GE9 A;  1FMK A;  2Y1M A;  1O46 A;  2SHP A;  4E68 A;  1O48 A;  1H9O A;  1A1B A;  3UYO A;  2SRC A;  2C9W A;  3CWG A;  2LQN A;  3GXW A;  1KC2 A;  3QWX X;  1O4K A;  1FBV A;  1KSW A;  2IZV A;  2QMS A;  2RSY A;  2L3T A;  2YSX A;  4FL2 A;  5GJH A;  3VGO A;  3ZNI A;  4JE4 A;  3VS5 A;  5BO4 A;  3MXC A;  4E93 A;  1PIC A;  1X6C A;  1F2F A;  4TZI A;  4K2R A;  1XA6 A;  2MQI A;  4XZ1 A;  1FBZ A;  3BUM B;  3N84 A;  5AUL A;  4DGP A;  1D4T A;  3GQI B;  2KNO A;  5J3X A;  1SKJ A;  2LCT A;  1M27 A;  3PSK A;  4F59 A;  4DGX A;  5I6V A;  2AOA A;  1SPS A;  4WWQ A;  2BBU A;  1SPR A;  1D4W A;  2Y3A B;  1O4C A;  4L1B B;  3S8N A;  5CDW A;  1O4A A;  1JU5 A;  2DLY A;  1IS0 A;  3K2M A;  1Y57 A;  2EO6 A;  1A81 A;  1JWO A;  1HCT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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