2K7AB

Ensemble structures of the binary complex between the sh3 and sh2 domain of interleukin-2 tyrosine kinase.
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
108
structure length
108
Chain Sequence
NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Proline Isomerization Preorganizes the Itk SH2 Domain for Binding to the Itk SH3 Domain
doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords SH3 domain of Tyrosine-protein kinase ITK/TSK
total genus 14
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2008-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2k7aB00
1WQUA 3US4A 1O4RA 1I3ZA 1A08A 2L4KA 4H1OA 1BMBA 3OV1A 2GSBA 4LUDA 3VROA 2OQ1A 4U17A 1FHSA 1O4LA 1P13A 3OVEA 3HHMB 3M7FA 3PLFB 2VIFA 3EACA 1UUSA 5AXIA 2LNWA 4JE4A 4ROJA 2EO6A 1JYUA 2IUIA 1MILA 2HMHA 2LQNA 4E68A 2MRKA 1BG1A 1F2FA 1GRIA 2ECDA 1RJAA 3GXWA 2FO0A 1RPYA 1PICA 1K9AA 3VRZA 1SHBA 1BM2A 2IUGA 1BKLA 3VS0A 2Y3AB 2C0TA 3VS3A 1M61A 3HIZB 1G83A 1FBZA 2H8HA 2MRJA 3MXCA 1JWOA 4K11A 3VS6A 1A09A 1A81A 5KAZA 2AUGA 3N8MA 1O4MA 2RVFA 3N7YA 1CSZA 2AOBA 1YVHA 2PLDA 3K2MA 3TL0A 2L6KA 1BHHB 2CIAA 3C7IA 1SKJA 3GQIB 1LUMA 3OB2B 1O4EA 1Y57A 2MK2A 3S9KA 1JU5A 1A1EA 2DVJA 5J3XA 5EHPA 4P9VA 1O4PA 1AYBA 1NRVA 1A07A 1O41A 4XZ0A 2IZVA 4FBNA 1O43A 3BUNB 1AYDA 4K44A 2LCTA 5HKYA 4NWFA 1NZLA 5I6VA 1O4QA 2CRHA 4JEGA 3VGOA 1OO3A 2PTKA 1KA6A 2DLZA 1RQQC 1CJ1A 1KSWA 1UURA 2EOBA 1QG1E 2LNXA 1YVLA 4X6SA 1AOTF 1O4OA 1R1SA 5BO4A 3VS4A 1LCJA 2CI8A 5DC4A 4FL3A 1O4GA 2HUWA 3OP0A 3VS1A 1LUNA 4WWQA 1O4IA 2MQIA 4A4CA 4OHHA 3UYOA 2DX0A 2GE9A 4LUEA 4GL9E 1SHAA 1BFJA 4OHDA 4OHEA 3QWYA 3S8LA 5GJHA 4GWFA 5DC9A 3VRPA 2L3TA 1SPSA 3BUXB 1O4FA 2ETZA 1O4CA 3PS5A 2QMSA 1O4JA 1FU5A 2H46E 1JYQA 1IJRA 1ZFPE 1TZEE 3TKZA 1QADA 4K2RA 1LKKA 3BKBA 3WA4A 5EEQA 1OPLA 1Z3KA 3OB1B 3CXLA 4L1BB 3CWGA 1O47A 3ZNIA 1TCEA 3PSKA 3NHNA 1HCTB 1X6CA 2BBUA 4U1PA 1BHFA 1KA7A 1B47A 2EL8A 1BLJA 4P9ZA 2SHPA 1BF5A 3CBLA 1AOUF 2B3OA 2IUHA 2DM0A 1F1WA 2PNBA 1Y1UA 1A1BA 1CWDL 4TZIA 1H9OA 1LKLA 1SHDA 2HDXA 3PJPA 5EG3B 3BUOB 1BKMA 4OHLA 3VRNA 2PLEA 2EU0A 3GXXA 1O46A 1LUKA 2PNAA 1O4BA 3CD3A 2YSXA 4OHIA 1D4WA 1AYCA 3IMJA 4NWGA 1LCKA 1O48A 3PSJA 2CI9A 2FCIA 1O4HA 2MC1A 1KC2A 2EO3A 4F5AA 2SRCA 1CWEA 1O4KA 3MXYA 1GHUA 1A1AA 3MAZA 4H34A 3T04A 1O4DA 1R1QA 4F5BA 3KFJA 3EAZA 1LUIA 3UF4A 4D8KA 2OZOA 1AD5A 5HKZA 1IS0A 1CSYA 2EYYA 1X27A 5EELA 4JGHA 2EKXA 3VRQA 2ABLA 1M27A 2K79B 1AB2A 4A4BA 1FU6A 3QWXX 4DGPA 5IBSA 5HKWA 2C9WA 2C0OA 2XP1A 2YU7A 3VS7A 1OO4A 2Y1NA 3VRYA 3VS2A 2DLYA 1D1ZA 1X0NA 1O4AA 1D4TA 3IN8A 5CDWA 1NZVA 4FL2A 1HCSB 4K45A 2RSYA 4GPLB 2C0IA 1O44A 5EHRA 2KK6A 2CS0A 4XZ1A 4F59A 2KNOA 1JYRA 2EYZA 5DC0B 3S8OA 1O45A 5AULA 3VRRA 3IN7A 3BUMB 2RORA 2AOAA 4EIHA 1BFIA 3PQZA 1SPRA 2DCRA 1A1CA 3HCKA 4QSYA 1R1PA 1OPKA 2H5KA 2CBLA 2JYQA 1O49A 3IMDA 4E93A 1BHHA 2EYVA 2Y1MA 5IBMA 4DGXA 4M4ZA 2HCKA 2K7AB 2CR4A 1FBVA 1AYAA 3PFVA 3VS5A 1BLKA 3N84A 1FYRA 2RMXA 5D0JA 1O4NA 2HDVA 1O42A 5DF6A 2LQWA 3S8NA 4EY0A 5GJIA 1MW4A 1XA6A 1QCFA 3BUWB 1FMKA
chains in the Genus database with same CATH superfamily
1WQUA 3US4A 1O4RA 1I3ZA 1A08A 2L4KA 4H1OA 1BMBA 3OV1A 2GSBA 4LUDA 3VROA 2OQ1A 4U17A 1FHSA 1O4LA 1P13A 3OVEA 3HHMB 3M7FA 3PLFB 2VIFA 3EACA 1UUSA 5AXIA 2LNWA 4JE4A 4ROJA 2EO6A 1JYUA 2IUIA 1MILA 2HMHA 2LQNA 4E68A 2MRKA 1BG1A 1F2FA 1GRIA 2ECDA 1RJAA 3GXWA 2FO0A 1RPYA 1PICA 1K9AA 3VRZA 1SHBA 1BM2A 2IUGA 1BKLA 3VS0A 2Y3AB 2C0TA 3VS3A 1M61A 3HIZB 1G83A 1FBZA 2H8HA 2MRJA 3MXCA 1JWOA 4K11A 3VS6A 1A09A 1A81A 5KAZA 2AUGA 3N8MA 1O4MA 2RVFA 3N7YA 1CSZA 2AOBA 1YVHA 2PLDA 3K2MA 3TL0A 2L6KA 1BHHB 2CIAA 3C7IA 1SKJA 3GQIB 1LUMA 3OB2B 1O4EA 1Y57A 2MK2A 3S9KA 1JU5A 1A1EA 2DVJA 5J3XA 5EHPA 4P9VA 1O4PA 1AYBA 1NRVA 1A07A 1O41A 4XZ0A 2IZVA 4FBNA 1O43A 3BUNB 1AYDA 4K44A 2LCTA 5HKYA 4NWFA 1NZLA 5I6VA 1O4QA 2CRHA 4JEGA 3VGOA 1OO3A 2PTKA 1KA6A 2DLZA 1RQQC 1CJ1A 1KSWA 1UURA 2EOBA 1QG1E 2LNXA 1YVLA 4X6SA 1AOTF 1O4OA 1R1SA 5BO4A 3VS4A 1LCJA 2CI8A 5DC4A 4FL3A 1O4GA 2HUWA 3OP0A 3VS1A 1LUNA 4WWQA 1O4IA 2MQIA 4A4CA 4OHHA 3UYOA 2DX0A 2GE9A 4LUEA 4GL9E 1SHAA 1BFJA 4OHDA 4OHEA 3QWYA 3S8LA 5GJHA 4GWFA 5DC9A 3VRPA 2L3TA 1SPSA 3BUXB 1O4FA 2ETZA 1O4CA 3PS5A 2QMSA 1O4JA 1FU5A 2H46E 1JYQA 1IJRA 1ZFPE 1TZEE 3TKZA 1QADA 4K2RA 1LKKA 3BKBA 3WA4A 5EEQA 1OPLA 1Z3KA 3OB1B 3CXLA 4L1BB 3CWGA 1O47A 3ZNIA 1TCEA 3PSKA 3NHNA 1HCTB 1X6CA 2BBUA 4U1PA 1BHFA 1KA7A 1B47A 2EL8A 1BLJA 4P9ZA 2SHPA 1BF5A 3CBLA 1AOUF 2B3OA 2IUHA 2DM0A 1F1WA 2PNBA 1Y1UA 1A1BA 1CWDL 4TZIA 1H9OA 3K2TA 1LKLA 1SHDA 2HDXA 3PJPA 5EG3B 3BUOB 1BKMA 4OHLA 3VRNA 2PLEA 2EU0A 3GXXA 1O46A 1LUKA 2PNAA 1O4BA 3CD3A 3LYVA 2YSXA 4OHIA 1D4WA 1AYCA 3IMJA 4NWGA 1LCKA 1O48A 3PSJA 2CI9A 2FCIA 1O4HA 2MC1A 1KC2A 2EO3A 4F5AA 2SRCA 1CWEA 1O4KA 3MXYA 1GHUA 1A1AA 3MAZA 4H34A 3T04A 1O4DA 1R1QA 4F5BA 3KFJA 3EAZA 1LUIA 3UF4A 4D8KA 2OZOA 1AD5A 5HKZA 1IS0A 1CSYA 2EYYA 1X27A 5EELA 4JGHA 2EKXA 3VRQA 2ABLA 1M27A 2K79B 1AB2A 4A4BA 1FU6A 3QWXX 4DGPA 5IBSA 5HKWA 2C9WA 2KGYA 2C0OA 2XP1A 2YU7A 3VS7A 1OO4A 2Y1NA 3VRYA 3VS2A 2DLYA 1D1ZA 1X0NA 1O4AA 1D4TA 3IN8A 5CDWA 1NZVA 4FL2A 1HCSB 4K45A 2RSYA 4GPLB 2C0IA 1O44A 5EHRA 2KK6A 2CS0A 4XZ1A 4F59A 2KNOA 1JYRA 2EYZA 5DC0B 3S8OA 1O45A 5AULA 3VRRA 3IN7A 3BUMB 2RORA 2AOAA 4EIHA 1BFIA 3PQZA 1SPRA 2DCRA 1A1CA 3HCKA 4QSYA 1R1PA 1OPKA 2H5KA 2CBLA 2JYQA 1O49A 3IMDA 4E93A 1BHHA 2EYVA 2Y1MA 5IBMA 4DGXA 4M4ZA 2HCKA 2LRAA 2K7AB 2CR4A 1FBVA 1AYAA 3PFVA 3VS5A 1BLKA 3N84A 1FYRA 2RMXA 5D0JA 1O4NA 2HDVA 1O42A 5DF6A 2LQWA 3S8NA 4EY0A 5GJIA 1MW4A 1XA6A 1QCFA 3BUWB 1FMKA
chains in the Genus database with same CATH topology
1WQUA 3US4A 1O4RA 1I3ZA 1A08A 2L4KA 4H1OA 1BMBA 3OV1A 2GSBA 4LUDA 3VROA 2OQ1A 4U17A 1FHSA 1O4LA 1P13A 3OVEA 3HHMB 3M7FA 3PLFB 2VIFA 3EACA 1UUSA 5AXIA 2LNWA 4JE4A 4ROJA 2EO6A 1JYUA 2IUIA 1MILA 2HMHA 2LQNA 4E68A 2MRKA 1BG1A 1F2FA 1GRIA 2ECDA 1RJAA 3GXWA 2FO0A 1RPYA 1PICA 1K9AA 3VRZA 1SHBA 1BM2A 2IUGA 1BKLA 3VS0A 2Y3AB 2C0TA 3VS3A 1M61A 3HIZB 1G83A 1FBZA 2H8HA 2MRJA 3MXCA 1JWOA 4K11A 3VS6A 1A09A 1A81A 5KAZA 2AUGA 3N8MA 1O4MA 2RVFA 3N7YA 1CSZA 2AOBA 1YVHA 2PLDA 3K2MA 3TL0A 2L6KA 1BHHB 2CIAA 3C7IA 1SKJA 3GQIB 1LUMA 3OB2B 1O4EA 1Y57A 2MK2A 3S9KA 1JU5A 1A1EA 2DVJA 5J3XA 5EHPA 4P9VA 1O4PA 1AYBA 1NRVA 1A07A 1O41A 4XZ0A 2IZVA 4FBNA 1O43A 3BUNB 1AYDA 4K44A 2LCTA 5HKYA 4NWFA 1NZLA 5I6VA 1O4QA 2CRHA 4JEGA 3VGOA 1OO3A 2PTKA 1KA6A 2DLZA 1RQQC 1CJ1A 1KSWA 1UURA 2EOBA 1QG1E 2LNXA 1YVLA 4X6SA 1AOTF 1O4OA 1R1SA 5BO4A 3VS4A 1LCJA 2CI8A 5DC4A 4FL3A 1O4GA 2HUWA 3OP0A 3VS1A 1LUNA 4WWQA 1O4IA 2MQIA 4A4CA 4OHHA 3UYOA 2DX0A 2GE9A 4LUEA 4GL9E 1SHAA 1BFJA 4OHDA 4OHEA 3QWYA 3S8LA 5GJHA 4GWFA 5DC9A 3VRPA 2L3TA 1SPSA 3BUXB 1O4FA 2ETZA 1O4CA 3PS5A 2QMSA 1O4JA 1FU5A 2H46E 1JYQA 1IJRA 1ZFPE 1TZEE 3TKZA 1QADA 4K2RA 1LKKA 3BKBA 3WA4A 5EEQA 1OPLA 1Z3KA 3OB1B 3CXLA 4L1BB 3CWGA 1O47A 3ZNIA 1TCEA 3PSKA 3NHNA 1HCTB 1X6CA 2BBUA 4U1PA 1BHFA 1KA7A 1B47A 2EL8A 1BLJA 4P9ZA 2SHPA 1BF5A 3CBLA 1AOUF 2B3OA 2IUHA 2DM0A 1F1WA 2PNBA 1Y1UA 1A1BA 1CWDL 4TZIA 1H9OA 1LKLA 1SHDA 2HDXA 3PJPA 5EG3B 3BUOB 1BKMA 4OHLA 3VRNA 2PLEA 2EU0A 3GXXA 1O46A 1LUKA 2PNAA 1O4BA 3CD3A 2YSXA 4OHIA 1D4WA 1AYCA 3IMJA 4NWGA 1LCKA 1O48A 3PSJA 2CI9A 2FCIA 1O4HA 2MC1A 1KC2A 2EO3A 4F5AA 2SRCA 1CWEA 1O4KA 3MXYA 1GHUA 1A1AA 3MAZA 4H34A 3T04A 1O4DA 1R1QA 4F5BA 3KFJA 3EAZA 1LUIA 3UF4A 4D8KA 2OZOA 1AD5A 5HKZA 1IS0A 1CSYA 2EYYA 1X27A 5EELA 4JGHA 2EKXA 3VRQA 2ABLA 1M27A 2K79B 1AB2A 4A4BA 1FU6A 3QWXX 4DGPA 5IBSA 5HKWA 2C9WA 2C0OA 2XP1A 2YU7A 3VS7A 1OO4A 2Y1NA 3VRYA 3VS2A 2DLYA 1D1ZA 1X0NA 1O4AA 1D4TA 3IN8A 5CDWA 1NZVA 4FL2A 1HCSB 4K45A 2RSYA 4GPLB 2C0IA 1O44A 5EHRA 2KK6A 2CS0A 4XZ1A 4F59A 2KNOA 1JYRA 2EYZA 5DC0B 3S8OA 1O45A 5AULA 3VRRA 3IN7A 3BUMB 2RORA 2AOAA 4EIHA 1BFIA 3PQZA 1SPRA 2DCRA 1A1CA 3HCKA 4QSYA 1R1PA 1OPKA 2H5KA 2CBLA 2JYQA 1O49A 3IMDA 4E93A 1BHHA 2EYVA 2Y1MA 5IBMA 4DGXA 4M4ZA 2HCKA 2K7AB 2CR4A 1FBVA 1AYAA 3PFVA 3VS5A 1BLKA 3N84A 1FYRA 2RMXA 5D0JA 1O4NA 2HDVA 1O42A 5DF6A 2LQWA 3S8NA 4EY0A 5GJIA 1MW4A 1XA6A 1QCFA 3BUWB 1FMKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQU A;  3US4 A;  1O4R A;  1I3Z A;  1A08 A;  2L4K A;  4H1O A;  1BMB A;  3OV1 A;  2GSB A;  4LUD A;  3VRO A;  2OQ1 A;  4U17 A;  1FHS A;  1O4L A;  1P13 A;  3OVE A;  3HHM B;  3M7F A;  3PLF B;  2VIF A;  3EAC A;  1UUS A;  5AXI A;  2LNW A;  4JE4 A;  4ROJ A;  2EO6 A;  1JYU A;  2IUI A;  1MIL A;  2HMH A;  2LQN A;  4E68 A;  2MRK A;  1BG1 A;  1F2F A;  1GRI A;  2ECD A;  1RJA A;  3GXW A;  2FO0 A;  1RPY A;  1PIC A;  1K9A A;  3VRZ A;  1SHB A;  1BM2 A;  2IUG A;  1BKL A;  3VS0 A;  2Y3A B;  2C0T A;  3VS3 A;  1M61 A;  3HIZ B;  1G83 A;  1FBZ A;  2H8H A;  2MRJ A;  3MXC A;  1JWO A;  4K11 A;  3VS6 A;  1A09 A;  1A81 A;  5KAZ A;  2AUG A;  3N8M A;  1O4M A;  2RVF A;  3N7Y A;  1CSZ A;  2AOB A;  1YVH A;  2PLD A;  3K2M A;  3TL0 A;  2L6K A;  1BHH B;  2CIA A;  3C7I A;  1SKJ A;  3GQI B;  1LUM A;  3OB2 B;  1O4E A;  1Y57 A;  2MK2 A;  3S9K A;  1JU5 A;  1A1E A;  2DVJ A;  5J3X A;  5EHP A;  4P9V A;  1O4P A;  1AYB A;  1NRV A;  1A07 A;  1O41 A;  4XZ0 A;  2IZV A;  4FBN A;  1O43 A;  3BUN B;  1AYD A;  4K44 A;  2LCT A;  5HKY A;  4NWF A;  1NZL A;  5I6V A;  1O4Q A;  2CRH A;  4JEG A;  3VGO A;  1OO3 A;  2PTK A;  1KA6 A;  2DLZ A;  1RQQ C;  1CJ1 A;  1KSW A;  1UUR A;  2EOB A;  1QG1 E;  2LNX A;  1YVL A;  4X6S A;  1AOT F;  1O4O A;  1R1S A;  5BO4 A;  3VS4 A;  1LCJ A;  2CI8 A;  5DC4 A;  4FL3 A;  1O4G A;  2HUW A;  3OP0 A;  3VS1 A;  1LUN A;  4WWQ A;  1O4I A;  2MQI A;  4A4C A;  4OHH A;  3UYO A;  2DX0 A;  2GE9 A;  4LUE A;  4GL9 E;  1SHA A;  1BFJ A;  4OHD A;  4OHE A;  3QWY A;  3S8L A;  5GJH A;  4GWF A;  5DC9 A;  3VRP A;  2L3T A;  1SPS A;  3BUX B;  1O4F A;  2ETZ A;  1O4C A;  3PS5 A;  2QMS A;  1O4J A;  1FU5 A;  2H46 E;  1JYQ A;  1IJR A;  1ZFP E;  1TZE E;  3TKZ A;  1QAD A;  4K2R A;  1LKK A;  3BKB A;  3WA4 A;  5EEQ A;  1OPL A;  1Z3K A;  3OB1 B;  3CXL A;  4L1B B;  3CWG A;  1O47 A;  3ZNI A;  1TCE A;  3PSK A;  3NHN A;  1HCT B;  1X6C A;  2BBU A;  4U1P A;  1BHF A;  1KA7 A;  1B47 A;  2EL8 A;  1BLJ A;  4P9Z A;  2SHP A;  1BF5 A;  3CBL A;  1AOU F;  2B3O A;  2IUH A;  2DM0 A;  1F1W A;  2PNB A;  1Y1U A;  1A1B A;  1CWD L;  4TZI A;  1H9O A;  1LKL A;  1SHD A;  2HDX A;  3PJP A;  5EG3 B;  3BUO B;  1BKM A;  4OHL A;  3VRN A;  2PLE A;  2EU0 A;  3GXX A;  1O46 A;  1LUK A;  2PNA A;  1O4B A;  3CD3 A;  2YSX A;  4OHI A;  1D4W A;  1AYC A;  3IMJ A;  4NWG A;  1LCK A;  1O48 A;  3PSJ A;  2CI9 A;  2FCI A;  1O4H A;  2MC1 A;  1KC2 A;  2EO3 A;  4F5A A;  2SRC A;  1CWE A;  1O4K A;  3MXY A;  1GHU A;  1A1A A;  3MAZ A;  4H34 A;  3T04 A;  1O4D A;  1R1Q A;  4F5B A;  3KFJ A;  3EAZ A;  1LUI A;  3UF4 A;  4D8K A;  2OZO A;  1AD5 A;  5HKZ A;  1IS0 A;  1CSY A;  2EYY A;  1X27 A;  5EEL A;  4JGH A;  2EKX A;  3VRQ A;  2ABL A;  1M27 A;  2K79 B;  1AB2 A;  4A4B A;  1FU6 A;  3QWX X;  4DGP A;  5IBS A;  5HKW A;  2C9W A;  2C0O A;  2XP1 A;  2YU7 A;  3VS7 A;  1OO4 A;  2Y1N A;  3VRY A;  3VS2 A;  2DLY A;  1D1Z A;  1X0N A;  1O4A A;  1D4T A;  3IN8 A;  5CDW A;  1NZV A;  4FL2 A;  1HCS B;  4K45 A;  2RSY A;  4GPL B;  2C0I A;  1O44 A;  5EHR A;  2KK6 A;  2CS0 A;  4XZ1 A;  4F59 A;  2KNO A;  1JYR A;  2EYZ A;  5DC0 B;  3S8O A;  1O45 A;  5AUL A;  3VRR A;  3IN7 A;  3BUM B;  2ROR A;  2AOA A;  4EIH A;  1BFI A;  3PQZ A;  1SPR A;  2DCR A;  1A1C A;  3HCK A;  4QSY A;  1R1P A;  1OPK A;  2H5K A;  2CBL A;  2JYQ A;  1O49 A;  3IMD A;  4E93 A;  1BHH A;  2EYV A;  2Y1M A;  5IBM A;  4DGX A;  4M4Z A;  2HCK A;  2K7A B;  2CR4 A;  1FBV A;  1AYA A;  3PFV A;  3VS5 A;  1BLK A;  3N84 A;  1FYR A;  2RMX A;  5D0J A;  1O4N A;  2HDV A;  1O42 A;  5DF6 A;  2LQW A;  3S8N A;  4EY0 A;  5GJI A;  1MW4 A;  1XA6 A;  1QCF A;  3BUW B;  1FMK A; 
#chains in the Genus database with same CATH topology
 1WQU A;  3US4 A;  1O4R A;  1I3Z A;  1A08 A;  2L4K A;  4H1O A;  1BMB A;  3OV1 A;  2GSB A;  4LUD A;  3VRO A;  2OQ1 A;  4U17 A;  1FHS A;  1O4L A;  1P13 A;  3OVE A;  3HHM B;  3M7F A;  3PLF B;  2VIF A;  3EAC A;  1UUS A;  5AXI A;  2LNW A;  4JE4 A;  4ROJ A;  2EO6 A;  1JYU A;  2IUI A;  1MIL A;  2HMH A;  2LQN A;  4E68 A;  2MRK A;  1BG1 A;  1F2F A;  1GRI A;  2ECD A;  1RJA A;  3GXW A;  2FO0 A;  1RPY A;  1PIC A;  1K9A A;  3VRZ A;  1SHB A;  1BM2 A;  2IUG A;  1BKL A;  3VS0 A;  2Y3A B;  2C0T A;  3VS3 A;  1M61 A;  3HIZ B;  1G83 A;  1FBZ A;  2H8H A;  2MRJ A;  3MXC A;  1JWO A;  4K11 A;  3VS6 A;  1A09 A;  1A81 A;  5KAZ A;  2AUG A;  3N8M A;  1O4M A;  2RVF A;  3N7Y A;  1CSZ A;  2AOB A;  1YVH A;  2PLD A;  3K2M A;  3TL0 A;  2L6K A;  1BHH B;  2CIA A;  3C7I A;  1SKJ A;  3GQI B;  1LUM A;  3OB2 B;  1O4E A;  1Y57 A;  2MK2 A;  3S9K A;  1JU5 A;  1A1E A;  2DVJ A;  5J3X A;  5EHP A;  4P9V A;  1O4P A;  1AYB A;  1NRV A;  1A07 A;  1O41 A;  4XZ0 A;  2IZV A;  4FBN A;  1O43 A;  3BUN B;  1AYD A;  4K44 A;  2LCT A;  5HKY A;  4NWF A;  1NZL A;  5I6V A;  1O4Q A;  2CRH A;  4JEG A;  3VGO A;  1OO3 A;  2PTK A;  1KA6 A;  2DLZ A;  1RQQ C;  1CJ1 A;  1KSW A;  1UUR A;  2EOB A;  1QG1 E;  2LNX A;  1YVL A;  4X6S A;  1AOT F;  1O4O A;  1R1S A;  5BO4 A;  3VS4 A;  1LCJ A;  2CI8 A;  5DC4 A;  4FL3 A;  1O4G A;  2HUW A;  3OP0 A;  3VS1 A;  1LUN A;  4WWQ A;  1O4I A;  2MQI A;  4A4C A;  4OHH A;  3UYO A;  2DX0 A;  2GE9 A;  4LUE A;  4GL9 E;  1SHA A;  1BFJ A;  4OHD A;  4OHE A;  3QWY A;  3S8L A;  5GJH A;  4GWF A;  5DC9 A;  3VRP A;  2L3T A;  1SPS A;  3BUX B;  1O4F A;  2ETZ A;  1O4C A;  3PS5 A;  2QMS A;  1O4J A;  1FU5 A;  2H46 E;  1JYQ A;  1IJR A;  1ZFP E;  1TZE E;  3TKZ A;  1QAD A;  4K2R A;  1LKK A;  3BKB A;  3WA4 A;  5EEQ A;  1OPL A;  1Z3K A;  3OB1 B;  3CXL A;  4L1B B;  3CWG A;  1O47 A;  3ZNI A;  1TCE A;  3PSK A;  3NHN A;  1HCT B;  1X6C A;  2BBU A;  4U1P A;  1BHF A;  1KA7 A;  1B47 A;  2EL8 A;  1BLJ A;  4P9Z A;  2SHP A;  1BF5 A;  3CBL A;  1AOU F;  2B3O A;  2IUH A;  2DM0 A;  1F1W A;  2PNB A;  1Y1U A;  1A1B A;  1CWD L;  4TZI A;  1H9O A;  3K2T A;  1LKL A;  1SHD A;  2HDX A;  3PJP A;  5EG3 B;  3BUO B;  1BKM A;  4OHL A;  3VRN A;  2PLE A;  2EU0 A;  3GXX A;  1O46 A;  1LUK A;  2PNA A;  1O4B A;  3CD3 A;  3LYV A;  2YSX A;  4OHI A;  1D4W A;  1AYC A;  3IMJ A;  4NWG A;  1LCK A;  1O48 A;  3PSJ A;  2CI9 A;  2FCI A;  1O4H A;  2MC1 A;  1KC2 A;  2EO3 A;  4F5A A;  2SRC A;  1CWE A;  1O4K A;  3MXY A;  1GHU A;  1A1A A;  3MAZ A;  4H34 A;  3T04 A;  1O4D A;  1R1Q A;  4F5B A;  3KFJ A;  3EAZ A;  1LUI A;  3UF4 A;  4D8K A;  2OZO A;  1AD5 A;  5HKZ A;  1IS0 A;  1CSY A;  2EYY A;  1X27 A;  5EEL A;  4JGH A;  2EKX A;  3VRQ A;  2ABL A;  1M27 A;  2K79 B;  1AB2 A;  4A4B A;  1FU6 A;  3QWX X;  4DGP A;  5IBS A;  5HKW A;  2C9W A;  2KGY A;  2C0O A;  2XP1 A;  2YU7 A;  3VS7 A;  1OO4 A;  2Y1N A;  3VRY A;  3VS2 A;  2DLY A;  1D1Z A;  1X0N A;  1O4A A;  1D4T A;  3IN8 A;  5CDW A;  1NZV A;  4FL2 A;  1HCS B;  4K45 A;  2RSY A;  4GPL B;  2C0I A;  1O44 A;  5EHR A;  2KK6 A;  2CS0 A;  4XZ1 A;  4F59 A;  2KNO A;  1JYR A;  2EYZ A;  5DC0 B;  3S8O A;  1O45 A;  5AUL A;  3VRR A;  3IN7 A;  3BUM B;  2ROR A;  2AOA A;  4EIH A;  1BFI A;  3PQZ A;  1SPR A;  2DCR A;  1A1C A;  3HCK A;  4QSY A;  1R1P A;  1OPK A;  2H5K A;  2CBL A;  2JYQ A;  1O49 A;  3IMD A;  4E93 A;  1BHH A;  2EYV A;  2Y1M A;  5IBM A;  4DGX A;  4M4Z A;  2HCK A;  2LRA A;  2K7A B;  2CR4 A;  1FBV A;  1AYA A;  3PFV A;  3VS5 A;  1BLK A;  3N84 A;  1FYR A;  2RMX A;  5D0J A;  1O4N A;  2HDV A;  1O42 A;  5DF6 A;  2LQW A;  3S8N A;  4EY0 A;  5GJI A;  1MW4 A;  1XA6 A;  1QCF A;  3BUW B;  1FMK A; 
#chains in the Genus database with same CATH homology
 1WQU A;  3US4 A;  1O4R A;  1I3Z A;  1A08 A;  2L4K A;  4H1O A;  1BMB A;  3OV1 A;  2GSB A;  4LUD A;  3VRO A;  2OQ1 A;  4U17 A;  1FHS A;  1O4L A;  1P13 A;  3OVE A;  3HHM B;  3M7F A;  3PLF B;  2VIF A;  3EAC A;  1UUS A;  5AXI A;  2LNW A;  4JE4 A;  4ROJ A;  2EO6 A;  1JYU A;  2IUI A;  1MIL A;  2HMH A;  2LQN A;  4E68 A;  2MRK A;  1BG1 A;  1F2F A;  1GRI A;  2ECD A;  1RJA A;  3GXW A;  2FO0 A;  1RPY A;  1PIC A;  1K9A A;  3VRZ A;  1SHB A;  1BM2 A;  2IUG A;  1BKL A;  3VS0 A;  2Y3A B;  2C0T A;  3VS3 A;  1M61 A;  3HIZ B;  1G83 A;  1FBZ A;  2H8H A;  2MRJ A;  3MXC A;  1JWO A;  4K11 A;  3VS6 A;  1A09 A;  1A81 A;  5KAZ A;  2AUG A;  3N8M A;  1O4M A;  2RVF A;  3N7Y A;  1CSZ A;  2AOB A;  1YVH A;  2PLD A;  3K2M A;  3TL0 A;  2L6K A;  1BHH B;  2CIA A;  3C7I A;  1SKJ A;  3GQI B;  1LUM A;  3OB2 B;  1O4E A;  1Y57 A;  2MK2 A;  3S9K A;  1JU5 A;  1A1E A;  2DVJ A;  5J3X A;  5EHP A;  4P9V A;  1O4P A;  1AYB A;  1NRV A;  1A07 A;  1O41 A;  4XZ0 A;  2IZV A;  4FBN A;  1O43 A;  3BUN B;  1AYD A;  4K44 A;  2LCT A;  5HKY A;  4NWF A;  1NZL A;  5I6V A;  1O4Q A;  2CRH A;  4JEG A;  3VGO A;  1OO3 A;  2PTK A;  1KA6 A;  2DLZ A;  1RQQ C;  1CJ1 A;  1KSW A;  1UUR A;  2EOB A;  1QG1 E;  2LNX A;  1YVL A;  4X6S A;  1AOT F;  1O4O A;  1R1S A;  5BO4 A;  3VS4 A;  1LCJ A;  2CI8 A;  5DC4 A;  4FL3 A;  1O4G A;  2HUW A;  3OP0 A;  3VS1 A;  1LUN A;  4WWQ A;  1O4I A;  2MQI A;  4A4C A;  4OHH A;  3UYO A;  2DX0 A;  2GE9 A;  4LUE A;  4GL9 E;  1SHA A;  1BFJ A;  4OHD A;  4OHE A;  3QWY A;  3S8L A;  5GJH A;  4GWF A;  5DC9 A;  3VRP A;  2L3T A;  1SPS A;  3BUX B;  1O4F A;  2ETZ A;  1O4C A;  3PS5 A;  2QMS A;  1O4J A;  1FU5 A;  2H46 E;  1JYQ A;  1IJR A;  1ZFP E;  1TZE E;  3TKZ A;  1QAD A;  4K2R A;  1LKK A;  3BKB A;  3WA4 A;  5EEQ A;  1OPL A;  1Z3K A;  3OB1 B;  3CXL A;  4L1B B;  3CWG A;  1O47 A;  3ZNI A;  1TCE A;  3PSK A;  3NHN A;  1HCT B;  1X6C A;  2BBU A;  4U1P A;  1BHF A;  1KA7 A;  1B47 A;  2EL8 A;  1BLJ A;  4P9Z A;  2SHP A;  1BF5 A;  3CBL A;  1AOU F;  2B3O A;  2IUH A;  2DM0 A;  1F1W A;  2PNB A;  1Y1U A;  1A1B A;  1CWD L;  4TZI A;  1H9O A;  1LKL A;  1SHD A;  2HDX A;  3PJP A;  5EG3 B;  3BUO B;  1BKM A;  4OHL A;  3VRN A;  2PLE A;  2EU0 A;  3GXX A;  1O46 A;  1LUK A;  2PNA A;  1O4B A;  3CD3 A;  2YSX A;  4OHI A;  1D4W A;  1AYC A;  3IMJ A;  4NWG A;  1LCK A;  1O48 A;  3PSJ A;  2CI9 A;  2FCI A;  1O4H A;  2MC1 A;  1KC2 A;  2EO3 A;  4F5A A;  2SRC A;  1CWE A;  1O4K A;  3MXY A;  1GHU A;  1A1A A;  3MAZ A;  4H34 A;  3T04 A;  1O4D A;  1R1Q A;  4F5B A;  3KFJ A;  3EAZ A;  1LUI A;  3UF4 A;  4D8K A;  2OZO A;  1AD5 A;  5HKZ A;  1IS0 A;  1CSY A;  2EYY A;  1X27 A;  5EEL A;  4JGH A;  2EKX A;  3VRQ A;  2ABL A;  1M27 A;  2K79 B;  1AB2 A;  4A4B A;  1FU6 A;  3QWX X;  4DGP A;  5IBS A;  5HKW A;  2C9W A;  2C0O A;  2XP1 A;  2YU7 A;  3VS7 A;  1OO4 A;  2Y1N A;  3VRY A;  3VS2 A;  2DLY A;  1D1Z A;  1X0N A;  1O4A A;  1D4T A;  3IN8 A;  5CDW A;  1NZV A;  4FL2 A;  1HCS B;  4K45 A;  2RSY A;  4GPL B;  2C0I A;  1O44 A;  5EHR A;  2KK6 A;  2CS0 A;  4XZ1 A;  4F59 A;  2KNO A;  1JYR A;  2EYZ A;  5DC0 B;  3S8O A;  1O45 A;  5AUL A;  3VRR A;  3IN7 A;  3BUM B;  2ROR A;  2AOA A;  4EIH A;  1BFI A;  3PQZ A;  1SPR A;  2DCR A;  1A1C A;  3HCK A;  4QSY A;  1R1P A;  1OPK A;  2H5K A;  2CBL A;  2JYQ A;  1O49 A;  3IMD A;  4E93 A;  1BHH A;  2EYV A;  2Y1M A;  5IBM A;  4DGX A;  4M4Z A;  2HCK A;  2K7A B;  2CR4 A;  1FBV A;  1AYA A;  3PFV A;  3VS5 A;  1BLK A;  3N84 A;  1FYR A;  2RMX A;  5D0J A;  1O4N A;  2HDV A;  1O42 A;  5DF6 A;  2LQW A;  3S8N A;  4EY0 A;  5GJI A;  1MW4 A;  1XA6 A;  1QCF A;  3BUW B;  1FMK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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