2MRJA

Structure of fyn protein sh2 bound
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
100
structure length
100
Chain Sequence
WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tyrosine-protein kinase Fyn
total genus 14
structure length 100
sequence length 100
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2014-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2mrjA00
2L4KA 2AUGA 3PFVA 1NZVA 1BHHA 1NZLA 1O4DA 3VS2A 2PLDA 3C7IA 1NRVA 3EAZA 2HDXA 1O4LA 1LUNA 3IN8A 5J3XA 3IN7A 3OV1A 1OO3A 2H8HA 2JYQA 3BKBA 1AOTF 1FHSA 3PSJA 2KNOA 4E68A 5KAZA 1P13A 5EHPA 1CSYA 4DGPA 2EKXA 3GXWA 1RPYA 1A1BA 3PSKA 1O49A 1FU6A 2IUIA 2MRJA 5IBSA 1X0NA 2IZVA 2FO0A 1O47A 2XP1A 5EELA 4OHHA 2DLZA 1LUIA 1Y1UA 2H5KA 1BKMA 1O41A 4K11A 2SRCA 5BO4A 1O46A 2H46E 4M4ZA 1KA7A 2DVJA 1HCTB 1M27A 3QWXX 1A08A 1MILA 1QG1E 3VRZA 2MK2A 3MAZA 3QWYA 2ECDA 3ZNIA 1PICA 4WWQA 2C0IA 4OHLA 2CI8A 4D8KA 2CS0A 2IUHA 2Y1NA 1R1PA 4U17A 3HIZB 3MXCA 4GPLB 1AD5A 1O4QA 1GHUA 1I3ZA 3PLFB 5GJHA 2L6KA 1OPKA 1KSWA 3VS1A 1UURA 4K44A 2DLYA 2C9WA 1KC2A 2LQNA 1KA6A 3VS7A 1CJ1A 4NWFA 4OHEA 5I6VA 2EL8A 3K2MA 1AYCA 5AXIA 3S8LA 1FU5A 3TKZA 1A81A 3GXXA 4FBNA 1IJRA 1O4OA 2C0OA 4K45A 1UUSA 1LCJA 4U1PA 3VS6A 1B47A 2VIFA 2K79B 4F5BA 1O4IA 2EYVA 1QCFA 4EY0A 3OB1B 1O43A 5AULA 1Y57A 1LUKA 2ETZA 2FCIA 1GRIA 1YVHA 3PQZA 1O48A 1SKJA 2HUWA 3PJPA 3VRRA 1O4PA 2MRKA 1LCKA 1O4MA 4XZ1A 1M61A 1WQUA 3VS4A 1SHDA 1D1ZA 4F59A 5DC0B 3KFJA 3BUNB 4FL2A 4F5AA 2EO3A 1R1SA 5DC9A 1CSZA 2AOBA 4K2RA 3N84A 2Y1MA 2SHPA 1A1AA 4OHIA 1X27A 2OZOA 5HKWA 1JWOA 2GE9A 3VROA 1TZEE 1F1WA 3CBLA 3N7YA 3VGOA 1XA6A 4ROJA 3VS5A 3NHNA 3WA4A 1BFIA 3N8MA 3HCKA 4FL3A 3BUXB 2EU0A 3S8OA 2OQ1A 3OP0A 5EG3B 2LCTA 2BBUA 3IMDA 1FYRA 2ABLA 1O45A 2L3TA 2MQIA 4JE4A 1O4BA 1FMKA 1AYBA 2Y3AB 3CD3A 4L1BB 1RJAA 3BUMB 2HDVA 1O4NA 2EO6A 3US4A 4QSYA 4E93A 2RSYA 4TZIA 2PLEA 1BG1A 4GL9E 2YU7A 1OPLA 2QMSA 1O4HA 1BHFA 4DGXA 2HCKA 1O44A 5IBMA 3VRYA 2RMXA 2K7AB 4P9VA 1AYDA 2PNBA 3CWGA 1OO4A 2AOAA 2LNWA 1AOUF 2RORA 1BM2A 1LUMA 2CI9A 1A07A 4A4CA 5EEQA 4A4BA 4OHDA 1CWEA 3PS5A 2MC1A 3VRPA 1JYRA 1O4RA 4JEGA 1BHHB 1O42A 2CRHA 5CDWA 1R1QA 1O4EA 1QADA 3IMJA 1LKKA 3UYOA 2KK6A 4EIHA 2RVFA 1SPRA 5GJIA 3HHMB 2DM0A 2HMHA 1ZFPE 1JYQA 2EYYA 3S8NA 1BMBA 1A09A 2CBLA 1A1EA 2IUGA 4X6SA 1O4AA 4H34A 5D0JA 5HKZA 5DF6A 1AB2A 1SPSA 4JGHA 1X6CA 2DX0A 2YSXA 2LQWA 1O4JA 3BUWB 2CR4A 1RQQC 2EOBA 3EACA 3MXYA 1YVLA 3UF4A 3VRQA 3TL0A 4LUEA 2PTKA 1D4WA 1F2FA 5EHRA 1O4FA 3CXLA 4NWGA 3T04A 2B3OA 3M7FA 3VRNA 2LNXA 1O4CA 1BLJA 2CIAA 3S9KA 3OB2B 1IS0A 1TCEA 1A1CA 1AYAA 2EYZA 4H1OA 1Z3KA 1BLKA 1FBVA 5HKYA 3VS3A 4LUDA 1BKLA 4P9ZA 4XZ0A 2C0TA 2DCRA 2PNAA 1JYUA 1CWDL 3BUOB 1K9AA 1SHBA 1MW4A 1BFJA 1HCSB 5DC4A 4GWFA 1BF5A 1O4KA 1G83A 1O4GA 1H9OA 3OVEA 1LKLA 3VS0A 1D4TA 1SHAA 1JU5A 3GQIB 1FBZA 2GSBA
chains in the Genus database with same CATH superfamily
2L4KA 2AUGA 3PFVA 1NZVA 1BHHA 1NZLA 1O4DA 3VS2A 2PLDA 3C7IA 1NRVA 3EAZA 2HDXA 1O4LA 1LUNA 3IN8A 5J3XA 3IN7A 3OV1A 1OO3A 2H8HA 2JYQA 3BKBA 1AOTF 1FHSA 3PSJA 2KNOA 4E68A 5KAZA 1P13A 5EHPA 1CSYA 4DGPA 2EKXA 3GXWA 1RPYA 1A1BA 3PSKA 1O49A 1FU6A 2IUIA 2MRJA 5IBSA 1X0NA 2IZVA 2FO0A 1O47A 2XP1A 5EELA 4OHHA 2DLZA 1LUIA 1Y1UA 2H5KA 1BKMA 1O41A 4K11A 2SRCA 5BO4A 1O46A 2H46E 4M4ZA 1KA7A 2DVJA 1HCTB 1M27A 3QWXX 1A08A 1MILA 1QG1E 3VRZA 2MK2A 3MAZA 3QWYA 2ECDA 3ZNIA 1PICA 4WWQA 2C0IA 4OHLA 2CI8A 4D8KA 2CS0A 2IUHA 2Y1NA 1R1PA 4U17A 3HIZB 3MXCA 4GPLB 1AD5A 1O4QA 1GHUA 1I3ZA 3PLFB 5GJHA 2L6KA 1OPKA 1KSWA 3VS1A 1UURA 4K44A 2DLYA 2C9WA 1KC2A 2LQNA 1KA6A 3VS7A 1CJ1A 4NWFA 4OHEA 5I6VA 2EL8A 3K2MA 1AYCA 5AXIA 3S8LA 1FU5A 3TKZA 1A81A 3GXXA 4FBNA 1IJRA 1O4OA 2C0OA 4K45A 1UUSA 1LCJA 4U1PA 3VS6A 1B47A 2VIFA 2K79B 4F5BA 1O4IA 2EYVA 1QCFA 4EY0A 3OB1B 1O43A 5AULA 1Y57A 1LUKA 2ETZA 2FCIA 1GRIA 1YVHA 3PQZA 1O48A 1SKJA 2HUWA 3PJPA 3VRRA 1O4PA 2MRKA 1LCKA 1O4MA 4XZ1A 1M61A 1WQUA 3VS4A 1SHDA 1D1ZA 4F59A 5DC0B 3KFJA 3BUNB 4FL2A 4F5AA 2EO3A 1R1SA 5DC9A 1CSZA 2AOBA 4K2RA 3N84A 2Y1MA 2SHPA 1A1AA 4OHIA 1X27A 2OZOA 5HKWA 1JWOA 2GE9A 3VROA 1TZEE 1F1WA 3CBLA 3N7YA 3VGOA 1XA6A 4ROJA 2LRAA 3VS5A 3NHNA 3WA4A 1BFIA 3N8MA 3HCKA 4FL3A 3BUXB 2EU0A 3S8OA 2OQ1A 3OP0A 5EG3B 2LCTA 2BBUA 3IMDA 1FYRA 2ABLA 1O45A 2KGYA 2L3TA 2MQIA 4JE4A 1O4BA 1FMKA 1AYBA 2Y3AB 3CD3A 4L1BB 1RJAA 3BUMB 2HDVA 1O4NA 2EO6A 3US4A 4QSYA 4E93A 2RSYA 4TZIA 2PLEA 1BG1A 4GL9E 2YU7A 1OPLA 2QMSA 1O4HA 1BHFA 4DGXA 2HCKA 1O44A 5IBMA 3VRYA 2RMXA 2K7AB 4P9VA 1AYDA 2PNBA 3CWGA 1OO4A 2AOAA 2LNWA 1AOUF 2RORA 1BM2A 1LUMA 2CI9A 1A07A 4A4CA 5EEQA 4A4BA 4OHDA 1CWEA 3PS5A 2MC1A 3VRPA 1JYRA 1O4RA 4JEGA 1BHHB 1O42A 2CRHA 5CDWA 1R1QA 1O4EA 1QADA 3IMJA 1LKKA 3UYOA 2KK6A 4EIHA 2RVFA 1SPRA 5GJIA 3HHMB 2DM0A 2HMHA 1ZFPE 1JYQA 2EYYA 3S8NA 1BMBA 1A09A 2CBLA 1A1EA 2IUGA 4X6SA 1O4AA 4H34A 5D0JA 5HKZA 5DF6A 1AB2A 1SPSA 4JGHA 1X6CA 2DX0A 2YSXA 2LQWA 1O4JA 3BUWB 2CR4A 1RQQC 2EOBA 3EACA 3MXYA 1YVLA 3UF4A 3VRQA 3TL0A 4LUEA 2PTKA 1D4WA 1F2FA 5EHRA 1O4FA 3CXLA 4NWGA 3T04A 2B3OA 3M7FA 3VRNA 2LNXA 1O4CA 1BLJA 2CIAA 3S9KA 3OB2B 1IS0A 1TCEA 1A1CA 1AYAA 2EYZA 4H1OA 1Z3KA 1BLKA 1FBVA 5HKYA 3VS3A 4LUDA 1BKLA 4P9ZA 4XZ0A 2C0TA 2DCRA 2PNAA 1JYUA 1CWDL 3BUOB 1K9AA 1SHBA 1MW4A 3LYVA 1BFJA 1HCSB 5DC4A 4GWFA 1BF5A 1O4KA 1G83A 1O4GA 1H9OA 3K2TA 3OVEA 1LKLA 3VS0A 1D4TA 1SHAA 1JU5A 3GQIB 1FBZA 2GSBA
chains in the Genus database with same CATH topology
2L4KA 2AUGA 3PFVA 1NZVA 1BHHA 1NZLA 1O4DA 3VS2A 2PLDA 3C7IA 1NRVA 3EAZA 2HDXA 1O4LA 1LUNA 3IN8A 5J3XA 3IN7A 3OV1A 1OO3A 2H8HA 2JYQA 3BKBA 1AOTF 1FHSA 3PSJA 2KNOA 4E68A 5KAZA 1P13A 5EHPA 1CSYA 4DGPA 2EKXA 3GXWA 1RPYA 1A1BA 3PSKA 1O49A 1FU6A 2IUIA 2MRJA 5IBSA 1X0NA 2IZVA 2FO0A 1O47A 2XP1A 5EELA 4OHHA 2DLZA 1LUIA 1Y1UA 2H5KA 1BKMA 1O41A 4K11A 2SRCA 5BO4A 1O46A 2H46E 4M4ZA 1KA7A 2DVJA 1HCTB 1M27A 3QWXX 1A08A 1MILA 1QG1E 3VRZA 2MK2A 3MAZA 3QWYA 2ECDA 3ZNIA 1PICA 4WWQA 2C0IA 4OHLA 2CI8A 4D8KA 2CS0A 2IUHA 2Y1NA 1R1PA 4U17A 3HIZB 3MXCA 4GPLB 1AD5A 1O4QA 1GHUA 1I3ZA 3PLFB 5GJHA 2L6KA 1OPKA 1KSWA 3VS1A 1UURA 4K44A 2DLYA 2C9WA 1KC2A 2LQNA 1KA6A 3VS7A 1CJ1A 4NWFA 4OHEA 5I6VA 2EL8A 3K2MA 1AYCA 5AXIA 3S8LA 1FU5A 3TKZA 1A81A 3GXXA 4FBNA 1IJRA 1O4OA 2C0OA 4K45A 1UUSA 1LCJA 4U1PA 3VS6A 1B47A 2VIFA 2K79B 4F5BA 1O4IA 2EYVA 1QCFA 4EY0A 3OB1B 1O43A 5AULA 1Y57A 1LUKA 2ETZA 2FCIA 1GRIA 1YVHA 3PQZA 1O48A 1SKJA 2HUWA 3PJPA 3VRRA 1O4PA 2MRKA 1LCKA 1O4MA 4XZ1A 1M61A 1WQUA 3VS4A 1SHDA 1D1ZA 4F59A 5DC0B 3KFJA 3BUNB 4FL2A 4F5AA 2EO3A 1R1SA 5DC9A 1CSZA 2AOBA 4K2RA 3N84A 2Y1MA 2SHPA 1A1AA 4OHIA 1X27A 2OZOA 5HKWA 1JWOA 2GE9A 3VROA 1TZEE 1F1WA 3CBLA 3N7YA 3VGOA 1XA6A 4ROJA 3VS5A 3NHNA 3WA4A 1BFIA 3N8MA 3HCKA 4FL3A 3BUXB 2EU0A 3S8OA 2OQ1A 3OP0A 5EG3B 2LCTA 2BBUA 3IMDA 1FYRA 2ABLA 1O45A 2L3TA 2MQIA 4JE4A 1O4BA 1FMKA 1AYBA 2Y3AB 3CD3A 4L1BB 1RJAA 3BUMB 2HDVA 1O4NA 2EO6A 3US4A 4QSYA 4E93A 2RSYA 4TZIA 2PLEA 1BG1A 4GL9E 2YU7A 1OPLA 2QMSA 1O4HA 1BHFA 4DGXA 2HCKA 1O44A 5IBMA 3VRYA 2RMXA 2K7AB 4P9VA 1AYDA 2PNBA 3CWGA 1OO4A 2AOAA 2LNWA 1AOUF 2RORA 1BM2A 1LUMA 2CI9A 1A07A 4A4CA 5EEQA 4A4BA 4OHDA 1CWEA 3PS5A 2MC1A 3VRPA 1JYRA 1O4RA 4JEGA 1BHHB 1O42A 2CRHA 5CDWA 1R1QA 1O4EA 1QADA 3IMJA 1LKKA 3UYOA 2KK6A 4EIHA 2RVFA 1SPRA 5GJIA 3HHMB 2DM0A 2HMHA 1ZFPE 1JYQA 2EYYA 3S8NA 1BMBA 1A09A 2CBLA 1A1EA 2IUGA 4X6SA 1O4AA 4H34A 5D0JA 5HKZA 5DF6A 1AB2A 1SPSA 4JGHA 1X6CA 2DX0A 2YSXA 2LQWA 1O4JA 3BUWB 2CR4A 1RQQC 2EOBA 3EACA 3MXYA 1YVLA 3UF4A 3VRQA 3TL0A 4LUEA 2PTKA 1D4WA 1F2FA 5EHRA 1O4FA 3CXLA 4NWGA 3T04A 2B3OA 3M7FA 3VRNA 2LNXA 1O4CA 1BLJA 2CIAA 3S9KA 3OB2B 1IS0A 1TCEA 1A1CA 1AYAA 2EYZA 4H1OA 1Z3KA 1BLKA 1FBVA 5HKYA 3VS3A 4LUDA 1BKLA 4P9ZA 4XZ0A 2C0TA 2DCRA 2PNAA 1JYUA 1CWDL 3BUOB 1K9AA 1SHBA 1MW4A 1BFJA 1HCSB 5DC4A 4GWFA 1BF5A 1O4KA 1G83A 1O4GA 1H9OA 3OVEA 1LKLA 3VS0A 1D4TA 1SHAA 1JU5A 3GQIB 1FBZA 2GSBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2L4K A;  2AUG A;  3PFV A;  1NZV A;  1BHH A;  1NZL A;  1O4D A;  3VS2 A;  2PLD A;  3C7I A;  1NRV A;  3EAZ A;  2HDX A;  1O4L A;  1LUN A;  3IN8 A;  5J3X A;  3IN7 A;  3OV1 A;  1OO3 A;  2H8H A;  2JYQ A;  3BKB A;  1AOT F;  1FHS A;  3PSJ A;  2KNO A;  4E68 A;  5KAZ A;  1P13 A;  5EHP A;  1CSY A;  4DGP A;  2EKX A;  3GXW A;  1RPY A;  1A1B A;  3PSK A;  1O49 A;  1FU6 A;  2IUI A;  2MRJ A;  5IBS A;  1X0N A;  2IZV A;  2FO0 A;  1O47 A;  2XP1 A;  5EEL A;  4OHH A;  2DLZ A;  1LUI A;  1Y1U A;  2H5K A;  1BKM A;  1O41 A;  4K11 A;  2SRC A;  5BO4 A;  1O46 A;  2H46 E;  4M4Z A;  1KA7 A;  2DVJ A;  1HCT B;  1M27 A;  3QWX X;  1A08 A;  1MIL A;  1QG1 E;  3VRZ A;  2MK2 A;  3MAZ A;  3QWY A;  2ECD A;  3ZNI A;  1PIC A;  4WWQ A;  2C0I A;  4OHL A;  2CI8 A;  4D8K A;  2CS0 A;  2IUH A;  2Y1N A;  1R1P A;  4U17 A;  3HIZ B;  3MXC A;  4GPL B;  1AD5 A;  1O4Q A;  1GHU A;  1I3Z A;  3PLF B;  5GJH A;  2L6K A;  1OPK A;  1KSW A;  3VS1 A;  1UUR A;  4K44 A;  2DLY A;  2C9W A;  1KC2 A;  2LQN A;  1KA6 A;  3VS7 A;  1CJ1 A;  4NWF A;  4OHE A;  5I6V A;  2EL8 A;  3K2M A;  1AYC A;  5AXI A;  3S8L A;  1FU5 A;  3TKZ A;  1A81 A;  3GXX A;  4FBN A;  1IJR A;  1O4O A;  2C0O A;  4K45 A;  1UUS A;  1LCJ A;  4U1P A;  3VS6 A;  1B47 A;  2VIF A;  2K79 B;  4F5B A;  1O4I A;  2EYV A;  1QCF A;  4EY0 A;  3OB1 B;  1O43 A;  5AUL A;  1Y57 A;  1LUK A;  2ETZ A;  2FCI A;  1GRI A;  1YVH A;  3PQZ A;  1O48 A;  1SKJ A;  2HUW A;  3PJP A;  3VRR A;  1O4P A;  2MRK A;  1LCK A;  1O4M A;  4XZ1 A;  1M61 A;  1WQU A;  3VS4 A;  1SHD A;  1D1Z A;  4F59 A;  5DC0 B;  3KFJ A;  3BUN B;  4FL2 A;  4F5A A;  2EO3 A;  1R1S A;  5DC9 A;  1CSZ A;  2AOB A;  4K2R A;  3N84 A;  2Y1M A;  2SHP A;  1A1A A;  4OHI A;  1X27 A;  2OZO A;  5HKW A;  1JWO A;  2GE9 A;  3VRO A;  1TZE E;  1F1W A;  3CBL A;  3N7Y A;  3VGO A;  1XA6 A;  4ROJ A;  3VS5 A;  3NHN A;  3WA4 A;  1BFI A;  3N8M A;  3HCK A;  4FL3 A;  3BUX B;  2EU0 A;  3S8O A;  2OQ1 A;  3OP0 A;  5EG3 B;  2LCT A;  2BBU A;  3IMD A;  1FYR A;  2ABL A;  1O45 A;  2L3T A;  2MQI A;  4JE4 A;  1O4B A;  1FMK A;  1AYB A;  2Y3A B;  3CD3 A;  4L1B B;  1RJA A;  3BUM B;  2HDV A;  1O4N A;  2EO6 A;  3US4 A;  4QSY A;  4E93 A;  2RSY A;  4TZI A;  2PLE A;  1BG1 A;  4GL9 E;  2YU7 A;  1OPL A;  2QMS A;  1O4H A;  1BHF A;  4DGX A;  2HCK A;  1O44 A;  5IBM A;  3VRY A;  2RMX A;  2K7A B;  4P9V A;  1AYD A;  2PNB A;  3CWG A;  1OO4 A;  2AOA A;  2LNW A;  1AOU F;  2ROR A;  1BM2 A;  1LUM A;  2CI9 A;  1A07 A;  4A4C A;  5EEQ A;  4A4B A;  4OHD A;  1CWE A;  3PS5 A;  2MC1 A;  3VRP A;  1JYR A;  1O4R A;  4JEG A;  1BHH B;  1O42 A;  2CRH A;  5CDW A;  1R1Q A;  1O4E A;  1QAD A;  3IMJ A;  1LKK A;  3UYO A;  2KK6 A;  4EIH A;  2RVF A;  1SPR A;  5GJI A;  3HHM B;  2DM0 A;  2HMH A;  1ZFP E;  1JYQ A;  2EYY A;  3S8N A;  1BMB A;  1A09 A;  2CBL A;  1A1E A;  2IUG A;  4X6S A;  1O4A A;  4H34 A;  5D0J A;  5HKZ A;  5DF6 A;  1AB2 A;  1SPS A;  4JGH A;  1X6C A;  2DX0 A;  2YSX A;  2LQW A;  1O4J A;  3BUW B;  2CR4 A;  1RQQ C;  2EOB A;  3EAC A;  3MXY A;  1YVL A;  3UF4 A;  3VRQ A;  3TL0 A;  4LUE A;  2PTK A;  1D4W A;  1F2F A;  5EHR A;  1O4F A;  3CXL A;  4NWG A;  3T04 A;  2B3O A;  3M7F A;  3VRN A;  2LNX A;  1O4C A;  1BLJ A;  2CIA A;  3S9K A;  3OB2 B;  1IS0 A;  1TCE A;  1A1C A;  1AYA A;  2EYZ A;  4H1O A;  1Z3K A;  1BLK A;  1FBV A;  5HKY A;  3VS3 A;  4LUD A;  1BKL A;  4P9Z A;  4XZ0 A;  2C0T A;  2DCR A;  2PNA A;  1JYU A;  1CWD L;  3BUO B;  1K9A A;  1SHB A;  1MW4 A;  1BFJ A;  1HCS B;  5DC4 A;  4GWF A;  1BF5 A;  1O4K A;  1G83 A;  1O4G A;  1H9O A;  3OVE A;  1LKL A;  3VS0 A;  1D4T A;  1SHA A;  1JU5 A;  3GQI B;  1FBZ A;  2GSB A; 
#chains in the Genus database with same CATH topology
 2L4K A;  2AUG A;  3PFV A;  1NZV A;  1BHH A;  1NZL A;  1O4D A;  3VS2 A;  2PLD A;  3C7I A;  1NRV A;  3EAZ A;  2HDX A;  1O4L A;  1LUN A;  3IN8 A;  5J3X A;  3IN7 A;  3OV1 A;  1OO3 A;  2H8H A;  2JYQ A;  3BKB A;  1AOT F;  1FHS A;  3PSJ A;  2KNO A;  4E68 A;  5KAZ A;  1P13 A;  5EHP A;  1CSY A;  4DGP A;  2EKX A;  3GXW A;  1RPY A;  1A1B A;  3PSK A;  1O49 A;  1FU6 A;  2IUI A;  2MRJ A;  5IBS A;  1X0N A;  2IZV A;  2FO0 A;  1O47 A;  2XP1 A;  5EEL A;  4OHH A;  2DLZ A;  1LUI A;  1Y1U A;  2H5K A;  1BKM A;  1O41 A;  4K11 A;  2SRC A;  5BO4 A;  1O46 A;  2H46 E;  4M4Z A;  1KA7 A;  2DVJ A;  1HCT B;  1M27 A;  3QWX X;  1A08 A;  1MIL A;  1QG1 E;  3VRZ A;  2MK2 A;  3MAZ A;  3QWY A;  2ECD A;  3ZNI A;  1PIC A;  4WWQ A;  2C0I A;  4OHL A;  2CI8 A;  4D8K A;  2CS0 A;  2IUH A;  2Y1N A;  1R1P A;  4U17 A;  3HIZ B;  3MXC A;  4GPL B;  1AD5 A;  1O4Q A;  1GHU A;  1I3Z A;  3PLF B;  5GJH A;  2L6K A;  1OPK A;  1KSW A;  3VS1 A;  1UUR A;  4K44 A;  2DLY A;  2C9W A;  1KC2 A;  2LQN A;  1KA6 A;  3VS7 A;  1CJ1 A;  4NWF A;  4OHE A;  5I6V A;  2EL8 A;  3K2M A;  1AYC A;  5AXI A;  3S8L A;  1FU5 A;  3TKZ A;  1A81 A;  3GXX A;  4FBN A;  1IJR A;  1O4O A;  2C0O A;  4K45 A;  1UUS A;  1LCJ A;  4U1P A;  3VS6 A;  1B47 A;  2VIF A;  2K79 B;  4F5B A;  1O4I A;  2EYV A;  1QCF A;  4EY0 A;  3OB1 B;  1O43 A;  5AUL A;  1Y57 A;  1LUK A;  2ETZ A;  2FCI A;  1GRI A;  1YVH A;  3PQZ A;  1O48 A;  1SKJ A;  2HUW A;  3PJP A;  3VRR A;  1O4P A;  2MRK A;  1LCK A;  1O4M A;  4XZ1 A;  1M61 A;  1WQU A;  3VS4 A;  1SHD A;  1D1Z A;  4F59 A;  5DC0 B;  3KFJ A;  3BUN B;  4FL2 A;  4F5A A;  2EO3 A;  1R1S A;  5DC9 A;  1CSZ A;  2AOB A;  4K2R A;  3N84 A;  2Y1M A;  2SHP A;  1A1A A;  4OHI A;  1X27 A;  2OZO A;  5HKW A;  1JWO A;  2GE9 A;  3VRO A;  1TZE E;  1F1W A;  3CBL A;  3N7Y A;  3VGO A;  1XA6 A;  4ROJ A;  2LRA A;  3VS5 A;  3NHN A;  3WA4 A;  1BFI A;  3N8M A;  3HCK A;  4FL3 A;  3BUX B;  2EU0 A;  3S8O A;  2OQ1 A;  3OP0 A;  5EG3 B;  2LCT A;  2BBU A;  3IMD A;  1FYR A;  2ABL A;  1O45 A;  2KGY A;  2L3T A;  2MQI A;  4JE4 A;  1O4B A;  1FMK A;  1AYB A;  2Y3A B;  3CD3 A;  4L1B B;  1RJA A;  3BUM B;  2HDV A;  1O4N A;  2EO6 A;  3US4 A;  4QSY A;  4E93 A;  2RSY A;  4TZI A;  2PLE A;  1BG1 A;  4GL9 E;  2YU7 A;  1OPL A;  2QMS A;  1O4H A;  1BHF A;  4DGX A;  2HCK A;  1O44 A;  5IBM A;  3VRY A;  2RMX A;  2K7A B;  4P9V A;  1AYD A;  2PNB A;  3CWG A;  1OO4 A;  2AOA A;  2LNW A;  1AOU F;  2ROR A;  1BM2 A;  1LUM A;  2CI9 A;  1A07 A;  4A4C A;  5EEQ A;  4A4B A;  4OHD A;  1CWE A;  3PS5 A;  2MC1 A;  3VRP A;  1JYR A;  1O4R A;  4JEG A;  1BHH B;  1O42 A;  2CRH A;  5CDW A;  1R1Q A;  1O4E A;  1QAD A;  3IMJ A;  1LKK A;  3UYO A;  2KK6 A;  4EIH A;  2RVF A;  1SPR A;  5GJI A;  3HHM B;  2DM0 A;  2HMH A;  1ZFP E;  1JYQ A;  2EYY A;  3S8N A;  1BMB A;  1A09 A;  2CBL A;  1A1E A;  2IUG A;  4X6S A;  1O4A A;  4H34 A;  5D0J A;  5HKZ A;  5DF6 A;  1AB2 A;  1SPS A;  4JGH A;  1X6C A;  2DX0 A;  2YSX A;  2LQW A;  1O4J A;  3BUW B;  2CR4 A;  1RQQ C;  2EOB A;  3EAC A;  3MXY A;  1YVL A;  3UF4 A;  3VRQ A;  3TL0 A;  4LUE A;  2PTK A;  1D4W A;  1F2F A;  5EHR A;  1O4F A;  3CXL A;  4NWG A;  3T04 A;  2B3O A;  3M7F A;  3VRN A;  2LNX A;  1O4C A;  1BLJ A;  2CIA A;  3S9K A;  3OB2 B;  1IS0 A;  1TCE A;  1A1C A;  1AYA A;  2EYZ A;  4H1O A;  1Z3K A;  1BLK A;  1FBV A;  5HKY A;  3VS3 A;  4LUD A;  1BKL A;  4P9Z A;  4XZ0 A;  2C0T A;  2DCR A;  2PNA A;  1JYU A;  1CWD L;  3BUO B;  1K9A A;  1SHB A;  1MW4 A;  3LYV A;  1BFJ A;  1HCS B;  5DC4 A;  4GWF A;  1BF5 A;  1O4K A;  1G83 A;  1O4G A;  1H9O A;  3K2T A;  3OVE A;  1LKL A;  3VS0 A;  1D4T A;  1SHA A;  1JU5 A;  3GQI B;  1FBZ A;  2GSB A; 
#chains in the Genus database with same CATH homology
 2L4K A;  2AUG A;  3PFV A;  1NZV A;  1BHH A;  1NZL A;  1O4D A;  3VS2 A;  2PLD A;  3C7I A;  1NRV A;  3EAZ A;  2HDX A;  1O4L A;  1LUN A;  3IN8 A;  5J3X A;  3IN7 A;  3OV1 A;  1OO3 A;  2H8H A;  2JYQ A;  3BKB A;  1AOT F;  1FHS A;  3PSJ A;  2KNO A;  4E68 A;  5KAZ A;  1P13 A;  5EHP A;  1CSY A;  4DGP A;  2EKX A;  3GXW A;  1RPY A;  1A1B A;  3PSK A;  1O49 A;  1FU6 A;  2IUI A;  2MRJ A;  5IBS A;  1X0N A;  2IZV A;  2FO0 A;  1O47 A;  2XP1 A;  5EEL A;  4OHH A;  2DLZ A;  1LUI A;  1Y1U A;  2H5K A;  1BKM A;  1O41 A;  4K11 A;  2SRC A;  5BO4 A;  1O46 A;  2H46 E;  4M4Z A;  1KA7 A;  2DVJ A;  1HCT B;  1M27 A;  3QWX X;  1A08 A;  1MIL A;  1QG1 E;  3VRZ A;  2MK2 A;  3MAZ A;  3QWY A;  2ECD A;  3ZNI A;  1PIC A;  4WWQ A;  2C0I A;  4OHL A;  2CI8 A;  4D8K A;  2CS0 A;  2IUH A;  2Y1N A;  1R1P A;  4U17 A;  3HIZ B;  3MXC A;  4GPL B;  1AD5 A;  1O4Q A;  1GHU A;  1I3Z A;  3PLF B;  5GJH A;  2L6K A;  1OPK A;  1KSW A;  3VS1 A;  1UUR A;  4K44 A;  2DLY A;  2C9W A;  1KC2 A;  2LQN A;  1KA6 A;  3VS7 A;  1CJ1 A;  4NWF A;  4OHE A;  5I6V A;  2EL8 A;  3K2M A;  1AYC A;  5AXI A;  3S8L A;  1FU5 A;  3TKZ A;  1A81 A;  3GXX A;  4FBN A;  1IJR A;  1O4O A;  2C0O A;  4K45 A;  1UUS A;  1LCJ A;  4U1P A;  3VS6 A;  1B47 A;  2VIF A;  2K79 B;  4F5B A;  1O4I A;  2EYV A;  1QCF A;  4EY0 A;  3OB1 B;  1O43 A;  5AUL A;  1Y57 A;  1LUK A;  2ETZ A;  2FCI A;  1GRI A;  1YVH A;  3PQZ A;  1O48 A;  1SKJ A;  2HUW A;  3PJP A;  3VRR A;  1O4P A;  2MRK A;  1LCK A;  1O4M A;  4XZ1 A;  1M61 A;  1WQU A;  3VS4 A;  1SHD A;  1D1Z A;  4F59 A;  5DC0 B;  3KFJ A;  3BUN B;  4FL2 A;  4F5A A;  2EO3 A;  1R1S A;  5DC9 A;  1CSZ A;  2AOB A;  4K2R A;  3N84 A;  2Y1M A;  2SHP A;  1A1A A;  4OHI A;  1X27 A;  2OZO A;  5HKW A;  1JWO A;  2GE9 A;  3VRO A;  1TZE E;  1F1W A;  3CBL A;  3N7Y A;  3VGO A;  1XA6 A;  4ROJ A;  3VS5 A;  3NHN A;  3WA4 A;  1BFI A;  3N8M A;  3HCK A;  4FL3 A;  3BUX B;  2EU0 A;  3S8O A;  2OQ1 A;  3OP0 A;  5EG3 B;  2LCT A;  2BBU A;  3IMD A;  1FYR A;  2ABL A;  1O45 A;  2L3T A;  2MQI A;  4JE4 A;  1O4B A;  1FMK A;  1AYB A;  2Y3A B;  3CD3 A;  4L1B B;  1RJA A;  3BUM B;  2HDV A;  1O4N A;  2EO6 A;  3US4 A;  4QSY A;  4E93 A;  2RSY A;  4TZI A;  2PLE A;  1BG1 A;  4GL9 E;  2YU7 A;  1OPL A;  2QMS A;  1O4H A;  1BHF A;  4DGX A;  2HCK A;  1O44 A;  5IBM A;  3VRY A;  2RMX A;  2K7A B;  4P9V A;  1AYD A;  2PNB A;  3CWG A;  1OO4 A;  2AOA A;  2LNW A;  1AOU F;  2ROR A;  1BM2 A;  1LUM A;  2CI9 A;  1A07 A;  4A4C A;  5EEQ A;  4A4B A;  4OHD A;  1CWE A;  3PS5 A;  2MC1 A;  3VRP A;  1JYR A;  1O4R A;  4JEG A;  1BHH B;  1O42 A;  2CRH A;  5CDW A;  1R1Q A;  1O4E A;  1QAD A;  3IMJ A;  1LKK A;  3UYO A;  2KK6 A;  4EIH A;  2RVF A;  1SPR A;  5GJI A;  3HHM B;  2DM0 A;  2HMH A;  1ZFP E;  1JYQ A;  2EYY A;  3S8N A;  1BMB A;  1A09 A;  2CBL A;  1A1E A;  2IUG A;  4X6S A;  1O4A A;  4H34 A;  5D0J A;  5HKZ A;  5DF6 A;  1AB2 A;  1SPS A;  4JGH A;  1X6C A;  2DX0 A;  2YSX A;  2LQW A;  1O4J A;  3BUW B;  2CR4 A;  1RQQ C;  2EOB A;  3EAC A;  3MXY A;  1YVL A;  3UF4 A;  3VRQ A;  3TL0 A;  4LUE A;  2PTK A;  1D4W A;  1F2F A;  5EHR A;  1O4F A;  3CXL A;  4NWG A;  3T04 A;  2B3O A;  3M7F A;  3VRN A;  2LNX A;  1O4C A;  1BLJ A;  2CIA A;  3S9K A;  3OB2 B;  1IS0 A;  1TCE A;  1A1C A;  1AYA A;  2EYZ A;  4H1O A;  1Z3K A;  1BLK A;  1FBV A;  5HKY A;  3VS3 A;  4LUD A;  1BKL A;  4P9Z A;  4XZ0 A;  2C0T A;  2DCR A;  2PNA A;  1JYU A;  1CWD L;  3BUO B;  1K9A A;  1SHB A;  1MW4 A;  1BFJ A;  1HCS B;  5DC4 A;  4GWF A;  1BF5 A;  1O4K A;  1G83 A;  1O4G A;  1H9O A;  3OVE A;  1LKL A;  3VS0 A;  1D4T A;  1SHA A;  1JU5 A;  3GQI B;  1FBZ A;  2GSB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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