2MRKA

Fyn sh2 domain in complex with the natural inhibitory phosphotyrosine peptide
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
100
structure length
100
Chain Sequence
WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tyrosine-protein kinase Fyn
total genus 15
structure length 100
sequence length 100
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2014-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2mrkA00
3OVEA 2MC1A 1BHHA 1O44A 2PTKA 2CIAA 5DC9A 4TZIA 1A81A 1OPLA 4P9VA 2EL8A 3C7IA 1H9OA 3BUOB 5HKYA 5CDWA 1PICA 1O4HA 4GL9E 1RJAA 1TCEA 2DM0A 2Y3AB 3KFJA 4M4ZA 1LKKA 2IUIA 2EO3A 5DC4A 5EHPA 1KC2A 3PJPA 4U17A 4NWGA 3BUMB 5BO4A 1AOTF 4FL3A 5GJIA 1KA6A 2DVJA 4K44A 4XZ0A 1BMBA 1MW4A 3IN7A 3UF4A 1BLKA 3HIZB 3VRQA 1GHUA 1A1BA 1CWEA 2LQWA 2IZVA 1BM2A 1BFJA 2PNAA 1LKLA 1CWDL 1O4PA 1A09A 4OHLA 2LQNA 4EY0A 4F59A 1O4LA 3M7FA 2BBUA 2L3TA 2OQ1A 1OPKA 1SPRA 2DLYA 3BKBA 4K45A 1CSZA 1LCKA 1O4CA 1A08A 1G83A 3MXCA 2ETZA 2MQIA 1NZLA 1BG1A 3IMJA 1F2FA 1OO4A 2SHPA 2XP1A 4E93A 1TZEE 1CSYA 1SHDA 5EEQA 1UURA 1FHSA 2MK2A 1O41A 1O43A 1QCFA 4GWFA 3VS1A 1D4WA 1A07A 2L6KA 1BHHB 2HDXA 2PLDA 1A1AA 1JYUA 3VRRA 3S8NA 4DGPA 3EAZA 1R1QA 3VS7A 3HHMB 3IN8A 1O47A 5I6VA 3CD3A 1A1EA 3GXWA 2LCTA 2EYZA 2L4KA 4OHEA 3CWGA 1AYDA 3BUNB 1A1CA 1O4EA 1JU5A 5D0JA 3PS5A 1AYCA 1SHAA 5DF6A 5AULA 1O45A 5HKWA 1O4GA 1Z3KA 1BKLA 1YVLA 1Y57A 4LUDA 3OB1B 5IBSA 1QADA 2K79B 2IUHA 1R1PA 1X27A 3TKZA 2Y1NA 4OHHA 1Y1UA 1FBVA 2HMHA 2ABLA 4A4CA 2VIFA 3N7YA 2QMSA 4XZ1A 3QWYA 4U1PA 2C0OA 1O49A 1BFIA 1M27A 1AYAA 4E68A 2H46E 4A4BA 2CI9A 3N8MA 1O4IA 4OHIA 3OV1A 2DLZA 2H8HA 3US4A 2Y1MA 5J3XA 4NWFA 1AOUF 2DX0A 2FCIA 4ROJA 3GQIB 2FO0A 1XA6A 2B3OA 1NRVA 1O4KA 2MRKA 5DC0B 4H34A 3CBLA 3K2MA 2AOAA 5HKZA 1JYRA 3CXLA 5GJHA 3QWXX 1SKJA 2CR4A 1FU6A 1IS0A 1OO3A 1AYBA 5KAZA 3VS2A 4D8KA 2EU0A 2LNWA 3EACA 1O48A 1YVHA 2EOBA 3VRPA 4GPLB 1LUIA 1LCJA 2MRJA 2OZOA 1FU5A 1HCTB 3VGOA 3S8LA 2RMXA 3VRZA 1F1WA 3TL0A 4K11A 5EHRA 3GXXA 2GSBA 5IBMA 4F5BA 1B47A 2IUGA 1M61A 1R1SA 1BKMA 1BLJA 2EYVA 1O4RA 3ZNIA 1SPSA 2KNOA 4FL2A 1CJ1A 1FYRA 4DGXA 3N84A 2AOBA 3VS0A 3VS3A 2EO6A 1O46A 1UUSA 3VRYA 1NZVA 3IMDA 5AXIA 3VRNA 2H5KA 3HCKA 4QSYA 2EKXA 2HCKA 4X6SA 1O4MA 1BHFA 4H1OA 2C0TA 4EIHA 1RPYA 1LUKA 2K7AB 2C9WA 2DCRA 3VS5A 3S9KA 3VROA 1K9AA 1ZFPE 2LNXA 1O4DA 1GRIA 3MAZA 1O4QA 1BF5A 1O4BA 2KK6A 3BUWB 1FMKA 4L1BB 2HDVA 2ECDA 3WA4A 2SRCA 4JGHA 1RQQC 3PLFB 4OHDA 4FBNA 3VS4A 1O4AA 1WQUA 3PQZA 1I3ZA 2EYYA 2RVFA 1O4JA 2CI8A 3UYOA 1MILA 1O4OA 2PNBA 3OP0A 1LUMA 1SHBA 4K2RA 4LUEA 2AUGA 3PSKA 1P13A 5EG3B 2JYQA 1LUNA 2YU7A 2RORA 1JWOA 1IJRA 2CRHA 3OB2B 3S8OA 3NHNA 1AD5A 2HUWA 4JEGA 1HCSB 2C0IA 3MXYA 1D4TA 1X6CA 1X0NA 1KA7A 3PSJA 1KSWA 1O42A 2CBLA 1QG1E 4WWQA 1O4FA 1JYQA 1FBZA 2YSXA 2PLEA 2RSYA 2CS0A 1O4NA 3PFVA 4JE4A 4F5AA 1D1ZA 5EELA 1AB2A 3BUXB 3T04A 2GE9A 4P9ZA 3VS6A
chains in the Genus database with same CATH superfamily
3OVEA 2MC1A 1BHHA 1O44A 2PTKA 2CIAA 5DC9A 4TZIA 1A81A 1OPLA 4P9VA 2EL8A 3C7IA 1H9OA 3BUOB 5HKYA 5CDWA 1PICA 1O4HA 4GL9E 1RJAA 1TCEA 2DM0A 2Y3AB 3KFJA 4M4ZA 1LKKA 2IUIA 2EO3A 5DC4A 5EHPA 1KC2A 3PJPA 4U17A 4NWGA 2KGYA 3BUMB 5BO4A 1AOTF 4FL3A 5GJIA 1KA6A 2DVJA 4K44A 4XZ0A 1BMBA 1MW4A 3IN7A 3UF4A 1BLKA 3HIZB 3VRQA 1GHUA 1A1BA 1CWEA 2LQWA 2IZVA 1BM2A 1BFJA 2PNAA 1LKLA 1CWDL 1O4PA 1A09A 4OHLA 2LQNA 4EY0A 4F59A 1O4LA 3M7FA 2BBUA 2L3TA 2OQ1A 1OPKA 1SPRA 2DLYA 3BKBA 4K45A 1CSZA 1LCKA 1O4CA 1A08A 1G83A 3MXCA 2ETZA 2MQIA 1NZLA 1BG1A 3IMJA 1F2FA 1OO4A 2SHPA 2XP1A 4E93A 1TZEE 1CSYA 1SHDA 5EEQA 1UURA 1FHSA 2MK2A 1O41A 1O43A 1QCFA 4GWFA 3VS1A 1D4WA 1A07A 2L6KA 1BHHB 2HDXA 2PLDA 1A1AA 1JYUA 3VRRA 3S8NA 4DGPA 3EAZA 1R1QA 3VS7A 3HHMB 3IN8A 1O47A 5I6VA 3CD3A 1A1EA 3GXWA 2LCTA 2EYZA 2L4KA 4OHEA 3CWGA 1AYDA 3BUNB 1A1CA 1O4EA 1JU5A 5D0JA 3PS5A 1AYCA 1SHAA 5DF6A 5AULA 1O45A 5HKWA 1O4GA 1Z3KA 1BKLA 1YVLA 1Y57A 4LUDA 3OB1B 5IBSA 1QADA 2K79B 2IUHA 1R1PA 1X27A 3TKZA 2Y1NA 4OHHA 1Y1UA 1FBVA 2HMHA 2ABLA 4A4CA 2VIFA 3N7YA 2QMSA 4XZ1A 3QWYA 4U1PA 2C0OA 1O49A 1BFIA 1M27A 1AYAA 4E68A 2H46E 4A4BA 2CI9A 3N8MA 1O4IA 4OHIA 3OV1A 2DLZA 2H8HA 3US4A 2Y1MA 5J3XA 4NWFA 1AOUF 2DX0A 2FCIA 4ROJA 3GQIB 2FO0A 1XA6A 2B3OA 1NRVA 1O4KA 2MRKA 5DC0B 4H34A 3CBLA 3K2MA 2AOAA 5HKZA 1JYRA 3CXLA 5GJHA 3QWXX 1SKJA 2CR4A 1FU6A 1IS0A 1OO3A 1AYBA 5KAZA 3VS2A 4D8KA 2EU0A 3LYVA 2LNWA 3EACA 1O48A 1YVHA 2EOBA 3VRPA 4GPLB 1LUIA 1LCJA 2MRJA 2OZOA 1FU5A 1HCTB 3VGOA 3S8LA 2RMXA 3VRZA 1F1WA 3TL0A 4K11A 5EHRA 3GXXA 2GSBA 5IBMA 4F5BA 1B47A 2IUGA 1M61A 1R1SA 1BKMA 1BLJA 2EYVA 1O4RA 3ZNIA 1SPSA 2KNOA 4FL2A 1CJ1A 1FYRA 4DGXA 3N84A 2AOBA 3VS0A 3VS3A 2EO6A 1O46A 1UUSA 3VRYA 1NZVA 3IMDA 5AXIA 3VRNA 2H5KA 3HCKA 4QSYA 2EKXA 2HCKA 4X6SA 1O4MA 1BHFA 4H1OA 2C0TA 4EIHA 1RPYA 1LUKA 2K7AB 2C9WA 2DCRA 3VS5A 3S9KA 3VROA 1K9AA 1ZFPE 2LNXA 1O4DA 1GRIA 3MAZA 1O4QA 1BF5A 1O4BA 2KK6A 3BUWB 1FMKA 4L1BB 2HDVA 2ECDA 3WA4A 2SRCA 4JGHA 1RQQC 3PLFB 4OHDA 4FBNA 3VS4A 1O4AA 1WQUA 3PQZA 1I3ZA 2EYYA 2RVFA 1O4JA 2CI8A 3UYOA 1MILA 1O4OA 2PNBA 3OP0A 1LUMA 1SHBA 3K2TA 4K2RA 4LUEA 2AUGA 3PSKA 2LRAA 1P13A 5EG3B 2JYQA 1LUNA 2YU7A 2RORA 1JWOA 1IJRA 2CRHA 3OB2B 3S8OA 3NHNA 1AD5A 2HUWA 4JEGA 1HCSB 2C0IA 3MXYA 1D4TA 1X6CA 1X0NA 1KA7A 3PSJA 1KSWA 1O42A 2CBLA 1QG1E 4WWQA 1O4FA 1JYQA 1FBZA 2YSXA 2PLEA 2RSYA 2CS0A 1O4NA 3PFVA 4JE4A 4F5AA 1D1ZA 5EELA 1AB2A 3BUXB 3T04A 2GE9A 4P9ZA 3VS6A
chains in the Genus database with same CATH topology
3OVEA 2MC1A 1BHHA 1O44A 2PTKA 2CIAA 5DC9A 4TZIA 1A81A 1OPLA 4P9VA 2EL8A 3C7IA 1H9OA 3BUOB 5HKYA 5CDWA 1PICA 1O4HA 4GL9E 1RJAA 1TCEA 2DM0A 2Y3AB 3KFJA 4M4ZA 1LKKA 2IUIA 2EO3A 5DC4A 5EHPA 1KC2A 3PJPA 4U17A 4NWGA 3BUMB 5BO4A 1AOTF 4FL3A 5GJIA 1KA6A 2DVJA 4K44A 4XZ0A 1BMBA 1MW4A 3IN7A 3UF4A 1BLKA 3HIZB 3VRQA 1GHUA 1A1BA 1CWEA 2LQWA 2IZVA 1BM2A 1BFJA 2PNAA 1LKLA 1CWDL 1O4PA 1A09A 4OHLA 2LQNA 4EY0A 4F59A 1O4LA 3M7FA 2BBUA 2L3TA 2OQ1A 1OPKA 1SPRA 2DLYA 3BKBA 4K45A 1CSZA 1LCKA 1O4CA 1A08A 1G83A 3MXCA 2ETZA 2MQIA 1NZLA 1BG1A 3IMJA 1F2FA 1OO4A 2SHPA 2XP1A 4E93A 1TZEE 1CSYA 1SHDA 5EEQA 1UURA 1FHSA 2MK2A 1O41A 1O43A 1QCFA 4GWFA 3VS1A 1D4WA 1A07A 2L6KA 1BHHB 2HDXA 2PLDA 1A1AA 1JYUA 3VRRA 3S8NA 4DGPA 3EAZA 1R1QA 3VS7A 3HHMB 3IN8A 1O47A 5I6VA 3CD3A 1A1EA 3GXWA 2LCTA 2EYZA 2L4KA 4OHEA 3CWGA 1AYDA 3BUNB 1A1CA 1O4EA 1JU5A 5D0JA 3PS5A 1AYCA 1SHAA 5DF6A 5AULA 1O45A 5HKWA 1O4GA 1Z3KA 1BKLA 1YVLA 1Y57A 4LUDA 3OB1B 5IBSA 1QADA 2K79B 2IUHA 1R1PA 1X27A 3TKZA 2Y1NA 4OHHA 1Y1UA 1FBVA 2HMHA 2ABLA 4A4CA 2VIFA 3N7YA 2QMSA 4XZ1A 3QWYA 4U1PA 2C0OA 1O49A 1BFIA 1M27A 1AYAA 4E68A 2H46E 4A4BA 2CI9A 3N8MA 1O4IA 4OHIA 3OV1A 2DLZA 2H8HA 3US4A 2Y1MA 5J3XA 4NWFA 1AOUF 2DX0A 2FCIA 4ROJA 3GQIB 2FO0A 1XA6A 2B3OA 1NRVA 1O4KA 2MRKA 5DC0B 4H34A 3CBLA 3K2MA 2AOAA 5HKZA 1JYRA 3CXLA 5GJHA 3QWXX 1SKJA 2CR4A 1FU6A 1IS0A 1OO3A 1AYBA 5KAZA 3VS2A 4D8KA 2EU0A 2LNWA 3EACA 1O48A 1YVHA 2EOBA 3VRPA 4GPLB 1LUIA 1LCJA 2MRJA 2OZOA 1FU5A 1HCTB 3VGOA 3S8LA 2RMXA 3VRZA 1F1WA 3TL0A 4K11A 5EHRA 3GXXA 2GSBA 5IBMA 4F5BA 1B47A 2IUGA 1M61A 1R1SA 1BKMA 1BLJA 2EYVA 1O4RA 3ZNIA 1SPSA 2KNOA 4FL2A 1CJ1A 1FYRA 4DGXA 3N84A 2AOBA 3VS0A 3VS3A 2EO6A 1O46A 1UUSA 3VRYA 1NZVA 3IMDA 5AXIA 3VRNA 2H5KA 3HCKA 4QSYA 2EKXA 2HCKA 4X6SA 1O4MA 1BHFA 4H1OA 2C0TA 4EIHA 1RPYA 1LUKA 2K7AB 2C9WA 2DCRA 3VS5A 3S9KA 3VROA 1K9AA 1ZFPE 2LNXA 1O4DA 1GRIA 3MAZA 1O4QA 1BF5A 1O4BA 2KK6A 3BUWB 1FMKA 4L1BB 2HDVA 2ECDA 3WA4A 2SRCA 4JGHA 1RQQC 3PLFB 4OHDA 4FBNA 3VS4A 1O4AA 1WQUA 3PQZA 1I3ZA 2EYYA 2RVFA 1O4JA 2CI8A 3UYOA 1MILA 1O4OA 2PNBA 3OP0A 1LUMA 1SHBA 4K2RA 4LUEA 2AUGA 3PSKA 1P13A 5EG3B 2JYQA 1LUNA 2YU7A 2RORA 1JWOA 1IJRA 2CRHA 3OB2B 3S8OA 3NHNA 1AD5A 2HUWA 4JEGA 1HCSB 2C0IA 3MXYA 1D4TA 1X6CA 1X0NA 1KA7A 3PSJA 1KSWA 1O42A 2CBLA 1QG1E 4WWQA 1O4FA 1JYQA 1FBZA 2YSXA 2PLEA 2RSYA 2CS0A 1O4NA 3PFVA 4JE4A 4F5AA 1D1ZA 5EELA 1AB2A 3BUXB 3T04A 2GE9A 4P9ZA 3VS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OVE A;  2MC1 A;  1BHH A;  1O44 A;  2PTK A;  2CIA A;  5DC9 A;  4TZI A;  1A81 A;  1OPL A;  4P9V A;  2EL8 A;  3C7I A;  1H9O A;  3BUO B;  5HKY A;  5CDW A;  1PIC A;  1O4H A;  4GL9 E;  1RJA A;  1TCE A;  2DM0 A;  2Y3A B;  3KFJ A;  4M4Z A;  1LKK A;  2IUI A;  2EO3 A;  5DC4 A;  5EHP A;  1KC2 A;  3PJP A;  4U17 A;  4NWG A;  3BUM B;  5BO4 A;  1AOT F;  4FL3 A;  5GJI A;  1KA6 A;  2DVJ A;  4K44 A;  4XZ0 A;  1BMB A;  1MW4 A;  3IN7 A;  3UF4 A;  1BLK A;  3HIZ B;  3VRQ A;  1GHU A;  1A1B A;  1CWE A;  2LQW A;  2IZV A;  1BM2 A;  1BFJ A;  2PNA A;  1LKL A;  1CWD L;  1O4P A;  1A09 A;  4OHL A;  2LQN A;  4EY0 A;  4F59 A;  1O4L A;  3M7F A;  2BBU A;  2L3T A;  2OQ1 A;  1OPK A;  1SPR A;  2DLY A;  3BKB A;  4K45 A;  1CSZ A;  1LCK A;  1O4C A;  1A08 A;  1G83 A;  3MXC A;  2ETZ A;  2MQI A;  1NZL A;  1BG1 A;  3IMJ A;  1F2F A;  1OO4 A;  2SHP A;  2XP1 A;  4E93 A;  1TZE E;  1CSY A;  1SHD A;  5EEQ A;  1UUR A;  1FHS A;  2MK2 A;  1O41 A;  1O43 A;  1QCF A;  4GWF A;  3VS1 A;  1D4W A;  1A07 A;  2L6K A;  1BHH B;  2HDX A;  2PLD A;  1A1A A;  1JYU A;  3VRR A;  3S8N A;  4DGP A;  3EAZ A;  1R1Q A;  3VS7 A;  3HHM B;  3IN8 A;  1O47 A;  5I6V A;  3CD3 A;  1A1E A;  3GXW A;  2LCT A;  2EYZ A;  2L4K A;  4OHE A;  3CWG A;  1AYD A;  3BUN B;  1A1C A;  1O4E A;  1JU5 A;  5D0J A;  3PS5 A;  1AYC A;  1SHA A;  5DF6 A;  5AUL A;  1O45 A;  5HKW A;  1O4G A;  1Z3K A;  1BKL A;  1YVL A;  1Y57 A;  4LUD A;  3OB1 B;  5IBS A;  1QAD A;  2K79 B;  2IUH A;  1R1P A;  1X27 A;  3TKZ A;  2Y1N A;  4OHH A;  1Y1U A;  1FBV A;  2HMH A;  2ABL A;  4A4C A;  2VIF A;  3N7Y A;  2QMS A;  4XZ1 A;  3QWY A;  4U1P A;  2C0O A;  1O49 A;  1BFI A;  1M27 A;  1AYA A;  4E68 A;  2H46 E;  4A4B A;  2CI9 A;  3N8M A;  1O4I A;  4OHI A;  3OV1 A;  2DLZ A;  2H8H A;  3US4 A;  2Y1M A;  5J3X A;  4NWF A;  1AOU F;  2DX0 A;  2FCI A;  4ROJ A;  3GQI B;  2FO0 A;  1XA6 A;  2B3O A;  1NRV A;  1O4K A;  2MRK A;  5DC0 B;  4H34 A;  3CBL A;  3K2M A;  2AOA A;  5HKZ A;  1JYR A;  3CXL A;  5GJH A;  3QWX X;  1SKJ A;  2CR4 A;  1FU6 A;  1IS0 A;  1OO3 A;  1AYB A;  5KAZ A;  3VS2 A;  4D8K A;  2EU0 A;  2LNW A;  3EAC A;  1O48 A;  1YVH A;  2EOB A;  3VRP A;  4GPL B;  1LUI A;  1LCJ A;  2MRJ A;  2OZO A;  1FU5 A;  1HCT B;  3VGO A;  3S8L A;  2RMX A;  3VRZ A;  1F1W A;  3TL0 A;  4K11 A;  5EHR A;  3GXX A;  2GSB A;  5IBM A;  4F5B A;  1B47 A;  2IUG A;  1M61 A;  1R1S A;  1BKM A;  1BLJ A;  2EYV A;  1O4R A;  3ZNI A;  1SPS A;  2KNO A;  4FL2 A;  1CJ1 A;  1FYR A;  4DGX A;  3N84 A;  2AOB A;  3VS0 A;  3VS3 A;  2EO6 A;  1O46 A;  1UUS A;  3VRY A;  1NZV A;  3IMD A;  5AXI A;  3VRN A;  2H5K A;  3HCK A;  4QSY A;  2EKX A;  2HCK A;  4X6S A;  1O4M A;  1BHF A;  4H1O A;  2C0T A;  4EIH A;  1RPY A;  1LUK A;  2K7A B;  2C9W A;  2DCR A;  3VS5 A;  3S9K A;  3VRO A;  1K9A A;  1ZFP E;  2LNX A;  1O4D A;  1GRI A;  3MAZ A;  1O4Q A;  1BF5 A;  1O4B A;  2KK6 A;  3BUW B;  1FMK A;  4L1B B;  2HDV A;  2ECD A;  3WA4 A;  2SRC A;  4JGH A;  1RQQ C;  3PLF B;  4OHD A;  4FBN A;  3VS4 A;  1O4A A;  1WQU A;  3PQZ A;  1I3Z A;  2EYY A;  2RVF A;  1O4J A;  2CI8 A;  3UYO A;  1MIL A;  1O4O A;  2PNB A;  3OP0 A;  1LUM A;  1SHB A;  4K2R A;  4LUE A;  2AUG A;  3PSK A;  1P13 A;  5EG3 B;  2JYQ A;  1LUN A;  2YU7 A;  2ROR A;  1JWO A;  1IJR A;  2CRH A;  3OB2 B;  3S8O A;  3NHN A;  1AD5 A;  2HUW A;  4JEG A;  1HCS B;  2C0I A;  3MXY A;  1D4T A;  1X6C A;  1X0N A;  1KA7 A;  3PSJ A;  1KSW A;  1O42 A;  2CBL A;  1QG1 E;  4WWQ A;  1O4F A;  1JYQ A;  1FBZ A;  2YSX A;  2PLE A;  2RSY A;  2CS0 A;  1O4N A;  3PFV A;  4JE4 A;  4F5A A;  1D1Z A;  5EEL A;  1AB2 A;  3BUX B;  3T04 A;  2GE9 A;  4P9Z A;  3VS6 A; 
#chains in the Genus database with same CATH topology
 3OVE A;  2MC1 A;  1BHH A;  1O44 A;  2PTK A;  2CIA A;  5DC9 A;  4TZI A;  1A81 A;  1OPL A;  4P9V A;  2EL8 A;  3C7I A;  1H9O A;  3BUO B;  5HKY A;  5CDW A;  1PIC A;  1O4H A;  4GL9 E;  1RJA A;  1TCE A;  2DM0 A;  2Y3A B;  3KFJ A;  4M4Z A;  1LKK A;  2IUI A;  2EO3 A;  5DC4 A;  5EHP A;  1KC2 A;  3PJP A;  4U17 A;  4NWG A;  2KGY A;  3BUM B;  5BO4 A;  1AOT F;  4FL3 A;  5GJI A;  1KA6 A;  2DVJ A;  4K44 A;  4XZ0 A;  1BMB A;  1MW4 A;  3IN7 A;  3UF4 A;  1BLK A;  3HIZ B;  3VRQ A;  1GHU A;  1A1B A;  1CWE A;  2LQW A;  2IZV A;  1BM2 A;  1BFJ A;  2PNA A;  1LKL A;  1CWD L;  1O4P A;  1A09 A;  4OHL A;  2LQN A;  4EY0 A;  4F59 A;  1O4L A;  3M7F A;  2BBU A;  2L3T A;  2OQ1 A;  1OPK A;  1SPR A;  2DLY A;  3BKB A;  4K45 A;  1CSZ A;  1LCK A;  1O4C A;  1A08 A;  1G83 A;  3MXC A;  2ETZ A;  2MQI A;  1NZL A;  1BG1 A;  3IMJ A;  1F2F A;  1OO4 A;  2SHP A;  2XP1 A;  4E93 A;  1TZE E;  1CSY A;  1SHD A;  5EEQ A;  1UUR A;  1FHS A;  2MK2 A;  1O41 A;  1O43 A;  1QCF A;  4GWF A;  3VS1 A;  1D4W A;  1A07 A;  2L6K A;  1BHH B;  2HDX A;  2PLD A;  1A1A A;  1JYU A;  3VRR A;  3S8N A;  4DGP A;  3EAZ A;  1R1Q A;  3VS7 A;  3HHM B;  3IN8 A;  1O47 A;  5I6V A;  3CD3 A;  1A1E A;  3GXW A;  2LCT A;  2EYZ A;  2L4K A;  4OHE A;  3CWG A;  1AYD A;  3BUN B;  1A1C A;  1O4E A;  1JU5 A;  5D0J A;  3PS5 A;  1AYC A;  1SHA A;  5DF6 A;  5AUL A;  1O45 A;  5HKW A;  1O4G A;  1Z3K A;  1BKL A;  1YVL A;  1Y57 A;  4LUD A;  3OB1 B;  5IBS A;  1QAD A;  2K79 B;  2IUH A;  1R1P A;  1X27 A;  3TKZ A;  2Y1N A;  4OHH A;  1Y1U A;  1FBV A;  2HMH A;  2ABL A;  4A4C A;  2VIF A;  3N7Y A;  2QMS A;  4XZ1 A;  3QWY A;  4U1P A;  2C0O A;  1O49 A;  1BFI A;  1M27 A;  1AYA A;  4E68 A;  2H46 E;  4A4B A;  2CI9 A;  3N8M A;  1O4I A;  4OHI A;  3OV1 A;  2DLZ A;  2H8H A;  3US4 A;  2Y1M A;  5J3X A;  4NWF A;  1AOU F;  2DX0 A;  2FCI A;  4ROJ A;  3GQI B;  2FO0 A;  1XA6 A;  2B3O A;  1NRV A;  1O4K A;  2MRK A;  5DC0 B;  4H34 A;  3CBL A;  3K2M A;  2AOA A;  5HKZ A;  1JYR A;  3CXL A;  5GJH A;  3QWX X;  1SKJ A;  2CR4 A;  1FU6 A;  1IS0 A;  1OO3 A;  1AYB A;  5KAZ A;  3VS2 A;  4D8K A;  2EU0 A;  3LYV A;  2LNW A;  3EAC A;  1O48 A;  1YVH A;  2EOB A;  3VRP A;  4GPL B;  1LUI A;  1LCJ A;  2MRJ A;  2OZO A;  1FU5 A;  1HCT B;  3VGO A;  3S8L A;  2RMX A;  3VRZ A;  1F1W A;  3TL0 A;  4K11 A;  5EHR A;  3GXX A;  2GSB A;  5IBM A;  4F5B A;  1B47 A;  2IUG A;  1M61 A;  1R1S A;  1BKM A;  1BLJ A;  2EYV A;  1O4R A;  3ZNI A;  1SPS A;  2KNO A;  4FL2 A;  1CJ1 A;  1FYR A;  4DGX A;  3N84 A;  2AOB A;  3VS0 A;  3VS3 A;  2EO6 A;  1O46 A;  1UUS A;  3VRY A;  1NZV A;  3IMD A;  5AXI A;  3VRN A;  2H5K A;  3HCK A;  4QSY A;  2EKX A;  2HCK A;  4X6S A;  1O4M A;  1BHF A;  4H1O A;  2C0T A;  4EIH A;  1RPY A;  1LUK A;  2K7A B;  2C9W A;  2DCR A;  3VS5 A;  3S9K A;  3VRO A;  1K9A A;  1ZFP E;  2LNX A;  1O4D A;  1GRI A;  3MAZ A;  1O4Q A;  1BF5 A;  1O4B A;  2KK6 A;  3BUW B;  1FMK A;  4L1B B;  2HDV A;  2ECD A;  3WA4 A;  2SRC A;  4JGH A;  1RQQ C;  3PLF B;  4OHD A;  4FBN A;  3VS4 A;  1O4A A;  1WQU A;  3PQZ A;  1I3Z A;  2EYY A;  2RVF A;  1O4J A;  2CI8 A;  3UYO A;  1MIL A;  1O4O A;  2PNB A;  3OP0 A;  1LUM A;  1SHB A;  3K2T A;  4K2R A;  4LUE A;  2AUG A;  3PSK A;  2LRA A;  1P13 A;  5EG3 B;  2JYQ A;  1LUN A;  2YU7 A;  2ROR A;  1JWO A;  1IJR A;  2CRH A;  3OB2 B;  3S8O A;  3NHN A;  1AD5 A;  2HUW A;  4JEG A;  1HCS B;  2C0I A;  3MXY A;  1D4T A;  1X6C A;  1X0N A;  1KA7 A;  3PSJ A;  1KSW A;  1O42 A;  2CBL A;  1QG1 E;  4WWQ A;  1O4F A;  1JYQ A;  1FBZ A;  2YSX A;  2PLE A;  2RSY A;  2CS0 A;  1O4N A;  3PFV A;  4JE4 A;  4F5A A;  1D1Z A;  5EEL A;  1AB2 A;  3BUX B;  3T04 A;  2GE9 A;  4P9Z A;  3VS6 A; 
#chains in the Genus database with same CATH homology
 3OVE A;  2MC1 A;  1BHH A;  1O44 A;  2PTK A;  2CIA A;  5DC9 A;  4TZI A;  1A81 A;  1OPL A;  4P9V A;  2EL8 A;  3C7I A;  1H9O A;  3BUO B;  5HKY A;  5CDW A;  1PIC A;  1O4H A;  4GL9 E;  1RJA A;  1TCE A;  2DM0 A;  2Y3A B;  3KFJ A;  4M4Z A;  1LKK A;  2IUI A;  2EO3 A;  5DC4 A;  5EHP A;  1KC2 A;  3PJP A;  4U17 A;  4NWG A;  3BUM B;  5BO4 A;  1AOT F;  4FL3 A;  5GJI A;  1KA6 A;  2DVJ A;  4K44 A;  4XZ0 A;  1BMB A;  1MW4 A;  3IN7 A;  3UF4 A;  1BLK A;  3HIZ B;  3VRQ A;  1GHU A;  1A1B A;  1CWE A;  2LQW A;  2IZV A;  1BM2 A;  1BFJ A;  2PNA A;  1LKL A;  1CWD L;  1O4P A;  1A09 A;  4OHL A;  2LQN A;  4EY0 A;  4F59 A;  1O4L A;  3M7F A;  2BBU A;  2L3T A;  2OQ1 A;  1OPK A;  1SPR A;  2DLY A;  3BKB A;  4K45 A;  1CSZ A;  1LCK A;  1O4C A;  1A08 A;  1G83 A;  3MXC A;  2ETZ A;  2MQI A;  1NZL A;  1BG1 A;  3IMJ A;  1F2F A;  1OO4 A;  2SHP A;  2XP1 A;  4E93 A;  1TZE E;  1CSY A;  1SHD A;  5EEQ A;  1UUR A;  1FHS A;  2MK2 A;  1O41 A;  1O43 A;  1QCF A;  4GWF A;  3VS1 A;  1D4W A;  1A07 A;  2L6K A;  1BHH B;  2HDX A;  2PLD A;  1A1A A;  1JYU A;  3VRR A;  3S8N A;  4DGP A;  3EAZ A;  1R1Q A;  3VS7 A;  3HHM B;  3IN8 A;  1O47 A;  5I6V A;  3CD3 A;  1A1E A;  3GXW A;  2LCT A;  2EYZ A;  2L4K A;  4OHE A;  3CWG A;  1AYD A;  3BUN B;  1A1C A;  1O4E A;  1JU5 A;  5D0J A;  3PS5 A;  1AYC A;  1SHA A;  5DF6 A;  5AUL A;  1O45 A;  5HKW A;  1O4G A;  1Z3K A;  1BKL A;  1YVL A;  1Y57 A;  4LUD A;  3OB1 B;  5IBS A;  1QAD A;  2K79 B;  2IUH A;  1R1P A;  1X27 A;  3TKZ A;  2Y1N A;  4OHH A;  1Y1U A;  1FBV A;  2HMH A;  2ABL A;  4A4C A;  2VIF A;  3N7Y A;  2QMS A;  4XZ1 A;  3QWY A;  4U1P A;  2C0O A;  1O49 A;  1BFI A;  1M27 A;  1AYA A;  4E68 A;  2H46 E;  4A4B A;  2CI9 A;  3N8M A;  1O4I A;  4OHI A;  3OV1 A;  2DLZ A;  2H8H A;  3US4 A;  2Y1M A;  5J3X A;  4NWF A;  1AOU F;  2DX0 A;  2FCI A;  4ROJ A;  3GQI B;  2FO0 A;  1XA6 A;  2B3O A;  1NRV A;  1O4K A;  2MRK A;  5DC0 B;  4H34 A;  3CBL A;  3K2M A;  2AOA A;  5HKZ A;  1JYR A;  3CXL A;  5GJH A;  3QWX X;  1SKJ A;  2CR4 A;  1FU6 A;  1IS0 A;  1OO3 A;  1AYB A;  5KAZ A;  3VS2 A;  4D8K A;  2EU0 A;  2LNW A;  3EAC A;  1O48 A;  1YVH A;  2EOB A;  3VRP A;  4GPL B;  1LUI A;  1LCJ A;  2MRJ A;  2OZO A;  1FU5 A;  1HCT B;  3VGO A;  3S8L A;  2RMX A;  3VRZ A;  1F1W A;  3TL0 A;  4K11 A;  5EHR A;  3GXX A;  2GSB A;  5IBM A;  4F5B A;  1B47 A;  2IUG A;  1M61 A;  1R1S A;  1BKM A;  1BLJ A;  2EYV A;  1O4R A;  3ZNI A;  1SPS A;  2KNO A;  4FL2 A;  1CJ1 A;  1FYR A;  4DGX A;  3N84 A;  2AOB A;  3VS0 A;  3VS3 A;  2EO6 A;  1O46 A;  1UUS A;  3VRY A;  1NZV A;  3IMD A;  5AXI A;  3VRN A;  2H5K A;  3HCK A;  4QSY A;  2EKX A;  2HCK A;  4X6S A;  1O4M A;  1BHF A;  4H1O A;  2C0T A;  4EIH A;  1RPY A;  1LUK A;  2K7A B;  2C9W A;  2DCR A;  3VS5 A;  3S9K A;  3VRO A;  1K9A A;  1ZFP E;  2LNX A;  1O4D A;  1GRI A;  3MAZ A;  1O4Q A;  1BF5 A;  1O4B A;  2KK6 A;  3BUW B;  1FMK A;  4L1B B;  2HDV A;  2ECD A;  3WA4 A;  2SRC A;  4JGH A;  1RQQ C;  3PLF B;  4OHD A;  4FBN A;  3VS4 A;  1O4A A;  1WQU A;  3PQZ A;  1I3Z A;  2EYY A;  2RVF A;  1O4J A;  2CI8 A;  3UYO A;  1MIL A;  1O4O A;  2PNB A;  3OP0 A;  1LUM A;  1SHB A;  4K2R A;  4LUE A;  2AUG A;  3PSK A;  1P13 A;  5EG3 B;  2JYQ A;  1LUN A;  2YU7 A;  2ROR A;  1JWO A;  1IJR A;  2CRH A;  3OB2 B;  3S8O A;  3NHN A;  1AD5 A;  2HUW A;  4JEG A;  1HCS B;  2C0I A;  3MXY A;  1D4T A;  1X6C A;  1X0N A;  1KA7 A;  3PSJ A;  1KSW A;  1O42 A;  2CBL A;  1QG1 E;  4WWQ A;  1O4F A;  1JYQ A;  1FBZ A;  2YSX A;  2PLE A;  2RSY A;  2CS0 A;  1O4N A;  3PFV A;  4JE4 A;  4F5A A;  1D1Z A;  5EEL A;  1AB2 A;  3BUX B;  3T04 A;  2GE9 A;  4P9Z A;  3VS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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