3GQIB

Crystal structure of activated receptor tyrosine kinase in complex with substrates
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
226
structure length
226
Chain Sequence
HSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
publication title The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.
pubmed doi rcsb
molecule keywords Basic fibroblast growth factor receptor 1
total genus 47
structure length 226
sequence length 226
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2009-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3gqiB02
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3gqiB01
1CWEA 1O45A 2ETZA 1O4LA 1O4NA 3KFJA 1BKMA 4JGHA 1G83A 2SRCA 4OHHA 1CSYA 1LKKA 1UUSA 1AYDA 1O4FA 4JEGA 2HMHA 3TL0A 3VRRA 4M4ZA 4NWFA 1QADA 2PNBA 1FBVA 1O4OA 2HDXA 4E68A 1RPYA 2EYVA 1FU6A 4QSYA 1LUIA 3PJPA 3VS5A 2DLZA 1BHHB 1O4MA 4D8KA 3VS0A 1OO3A 3VS4A 2OZOA 2CRHA 3GQIB 3NHNA 2L3TA 3OV1A 1X0NA 2C0OA 2DCRA 3BUNB 2ECDA 1BMBA 1KC2A 2FCIA 2K79B 1ZFPE 4F59A 1H9OA 1JYRA 5EHRA 1CWDL 1YVHA 1SPRA 2DX0A 5HKYA 1BFIA 2CI9A 3S8OA 3GXWA 1BHFA 2LQNA 1O4DA 4E93A 3S8LA 4H1OA 2XP1A 4ROJA 2IUIA 1XA6A 2CI8A 2H5KA 4XZ0A 1FBZA 1JYUA 1WQUA 5EELA 1BM2A 1QCFA 4DGPA 1A1AA 2PLEA 1X6CA 1NZVA 5AXIA 4K11A 2VIFA 5I6VA 1KA7A 1O4PA 1O46A 1A07A 2MRJA 3VRYA 3CBLA 1BLJA 2Y1MA 1AB2A 1O42A 2OQ1A 2EO3A 1SHAA 1KA6A 1AYBA 2HUWA 5DC4A 5IBMA 2K7AB 4L1BB 2RVFA 1A1EA 1Y57A 3CD3A 1HCTB 3EAZA 4GPLB 3BUOB 4EY0A 1OO4A 1FU5A 1Z3KA 3VRZA 1JYQA 3VGOA 3OB2B 1O4AA 2EL8A 1D1ZA 1UURA 2ABLA 2IUGA 3IN8A 4F5AA 3VS6A 3IMDA 3TKZA 1AYCA 1D4TA 1LKLA 4FL3A 1A1CA 2QMSA 1KSWA 3BUMB 4OHDA 2KK6A 1R1PA 3K2MA 5EEQA 2H46E 3IN7A 1LCKA 4X6SA 3S9KA 2FO0A 1LUNA 1JU5A 2LCTA 1TZEE 3VRPA 1GHUA 2MK2A 3QWYA 1M27A 3VRQA 1FMKA 3VROA 3UF4A 3HIZB 4P9ZA 2Y3AB 1MILA 3OB1B 5EG3B 4K2RA 3IMJA 2IUHA 2L6KA 5GJHA 1SHDA 1AD5A 1HCSB 4F5BA 4XZ1A 3S8NA 1O4IA 4A4CA 5J3XA 1A81A 1O44A 1OPKA 4U17A 1NRVA 1A08A 1BHHA 2RORA 4OHEA 2SHPA 2Y1NA 3PSKA 2GSBA 2CS0A 3PQZA 1NZLA 1PICA 1O49A 3QWXX 1X27A 1O4HA 3M7FA 1B47A 5HKZA 5DF6A 2DM0A 3VS2A 2BBUA 1SKJA 2MRKA 1IJRA 2YU7A 1BKLA 1TCEA 2CIAA 1BF5A 2MQIA 1JWOA 5EHPA 4DGXA 3PS5A 4LUDA 1GRIA 5DC0B 3OP0A 1O4QA 3VS7A 2DLYA 1O4RA 4A4BA 1D4WA 1LCJA 1O4KA 1O4JA 4JE4A 2KNOA 4H34A 3MAZA 2LQWA 1BG1A 1BFJA 4GL9E 5KAZA 3BUXB 2EYZA 1QG1E 2EO6A 2PLDA 1AYAA 1CSZA 2CR4A 1O48A 2HDVA 3PFVA 2C0TA 2EYYA 3GXXA 2MC1A 4FL2A 3N7YA 1K9AA 3C7IA 4EIHA 1M61A 1R1QA 4LUEA 2RSYA 2GE9A 2JYQA 5DC9A 2LNWA 4FBNA 3CXLA 1O4BA 5AULA 1FYRA 1O47A 1O4CA 3HHMB 1O41A 3N8MA 4K45A 4P9VA 3CWGA 1SPSA 1LUKA 2AOBA 3T04A 3PLFB 1RQQC 2HCKA 4TZIA 1O4EA 1LUMA 3N84A 2L4KA 1BLKA 3OVEA 1AOUF 3BKBA 1YVLA 1RJAA 2B3OA 2EU0A 1IS0A 1MW4A 2DVJA 3WA4A 1R1SA 5HKWA 5BO4A 3VS1A 1F1WA 2H8HA 5GJIA 5IBSA 1AOTF 1OPLA 1A1BA 3HCKA 1CJ1A 4K44A 3US4A 3PSJA 4GWFA 2IZVA 3BUWB 2C0IA 2AUGA 5D0JA 2LNXA 4U1PA 1O4GA 1I3ZA 2EKXA 2RMXA 3VS3A 2PNAA 2EOBA 4WWQA 3VRNA 1SHBA 3ZNIA 1FHSA 2PTKA 1A09A 2CBLA 1P13A 4OHIA 2AOAA 3UYOA 3MXYA 1F2FA 2YSXA 4OHLA 3MXCA 1O43A 5CDWA 2C9WA 4NWGA 3EACA 1Y1UA
chains in the Genus database with same CATH superfamily
1CWEA 1O45A 2ETZA 1O4LA 1O4NA 3KFJA 1BKMA 4JGHA 1G83A 2SRCA 4OHHA 1CSYA 1LKKA 1UUSA 1AYDA 1O4FA 3K2TA 4JEGA 2HMHA 3TL0A 3VRRA 4M4ZA 4NWFA 1QADA 2PNBA 1FBVA 1O4OA 2HDXA 4E68A 1RPYA 2EYVA 1FU6A 4QSYA 1LUIA 3PJPA 3VS5A 2DLZA 1BHHB 1O4MA 4D8KA 3VS0A 1OO3A 3VS4A 2OZOA 2CRHA 3GQIB 3NHNA 2L3TA 3OV1A 1X0NA 2C0OA 2DCRA 3BUNB 2ECDA 1BMBA 1KC2A 2FCIA 2K79B 1ZFPE 4F59A 1H9OA 1JYRA 5EHRA 1CWDL 1YVHA 1SPRA 2DX0A 5HKYA 1BFIA 2CI9A 3S8OA 3GXWA 1BHFA 2LQNA 1O4DA 4E93A 3S8LA 4H1OA 2XP1A 4ROJA 2IUIA 1XA6A 2CI8A 2H5KA 4XZ0A 1FBZA 1JYUA 1WQUA 5EELA 1BM2A 1QCFA 4DGPA 1A1AA 2PLEA 1X6CA 1NZVA 5AXIA 4K11A 2VIFA 5I6VA 1KA7A 1O4PA 1O46A 1A07A 2MRJA 3VRYA 3CBLA 1BLJA 2Y1MA 1AB2A 1O42A 2OQ1A 2EO3A 1SHAA 1KA6A 1AYBA 2HUWA 5DC4A 5IBMA 2K7AB 4L1BB 2RVFA 1A1EA 1Y57A 3CD3A 1HCTB 3EAZA 4GPLB 3BUOB 4EY0A 1OO4A 1FU5A 1Z3KA 3VRZA 1JYQA 3VGOA 3OB2B 1O4AA 2EL8A 1D1ZA 1UURA 2ABLA 2IUGA 3IN8A 4F5AA 3VS6A 3IMDA 3TKZA 1AYCA 1D4TA 1LKLA 4FL3A 1A1CA 2QMSA 1KSWA 3BUMB 4OHDA 2KK6A 1R1PA 3K2MA 5EEQA 2H46E 3IN7A 1LCKA 4X6SA 3S9KA 2FO0A 1LUNA 1JU5A 2LCTA 1TZEE 3VRPA 1GHUA 2MK2A 3QWYA 1M27A 3VRQA 1FMKA 3VROA 3UF4A 3HIZB 4P9ZA 2Y3AB 1MILA 3OB1B 5EG3B 4K2RA 3IMJA 2IUHA 2L6KA 5GJHA 1SHDA 1AD5A 1HCSB 4F5BA 4XZ1A 3S8NA 1O4IA 4A4CA 5J3XA 1A81A 1O44A 1OPKA 4U17A 1NRVA 1A08A 1BHHA 2RORA 4OHEA 2SHPA 2Y1NA 3PSKA 2GSBA 2CS0A 3PQZA 1NZLA 1PICA 1O49A 3QWXX 1X27A 1O4HA 3M7FA 1B47A 5HKZA 5DF6A 2DM0A 3VS2A 2BBUA 1SKJA 2MRKA 1IJRA 2YU7A 1BKLA 1TCEA 2CIAA 1BF5A 2MQIA 1JWOA 5EHPA 4DGXA 3PS5A 4LUDA 1GRIA 5DC0B 3OP0A 1O4QA 3VS7A 2DLYA 1O4RA 4A4BA 1D4WA 1LCJA 1O4KA 1O4JA 4JE4A 2KNOA 4H34A 3MAZA 2LRAA 2LQWA 1BG1A 1BFJA 4GL9E 5KAZA 3BUXB 2EYZA 1QG1E 2EO6A 2PLDA 1AYAA 1CSZA 2CR4A 1O48A 2HDVA 3PFVA 3LYVA 2C0TA 2EYYA 3GXXA 2MC1A 4FL2A 3N7YA 1K9AA 3C7IA 4EIHA 1M61A 1R1QA 4LUEA 2RSYA 2GE9A 2JYQA 5DC9A 2LNWA 4FBNA 3CXLA 1O4BA 5AULA 1FYRA 1O47A 1O4CA 3HHMB 1O41A 3N8MA 4K45A 4P9VA 3CWGA 1SPSA 1LUKA 2AOBA 3T04A 3PLFB 1RQQC 2HCKA 4TZIA 1O4EA 1LUMA 3N84A 2L4KA 1BLKA 3OVEA 1AOUF 3BKBA 1YVLA 1RJAA 2B3OA 2EU0A 1IS0A 1MW4A 2DVJA 3WA4A 1R1SA 5HKWA 5BO4A 3VS1A 1F1WA 2H8HA 5GJIA 5IBSA 1AOTF 1OPLA 1A1BA 3HCKA 1CJ1A 4K44A 3US4A 3PSJA 4GWFA 2IZVA 3BUWB 2C0IA 2AUGA 5D0JA 2LNXA 4U1PA 1O4GA 1I3ZA 2EKXA 2RMXA 3VS3A 2PNAA 2EOBA 4WWQA 3VRNA 1SHBA 3ZNIA 1FHSA 2PTKA 1A09A 2CBLA 1P13A 4OHIA 2AOAA 3UYOA 3MXYA 1F2FA 2YSXA 4OHLA 3MXCA 1O43A 5CDWA 2C9WA 2KGYA 4NWGA 3EACA 1Y1UA
chains in the Genus database with same CATH topology
1CWEA 1O45A 2ETZA 1O4LA 1O4NA 3KFJA 1BKMA 4JGHA 1G83A 2SRCA 4OHHA 1CSYA 1LKKA 1UUSA 1AYDA 1O4FA 4JEGA 2HMHA 3TL0A 3VRRA 4M4ZA 4NWFA 1QADA 2PNBA 1FBVA 1O4OA 2HDXA 4E68A 1RPYA 2EYVA 1FU6A 4QSYA 1LUIA 3PJPA 3VS5A 2DLZA 1BHHB 1O4MA 4D8KA 3VS0A 1OO3A 3VS4A 2OZOA 2CRHA 3GQIB 3NHNA 2L3TA 3OV1A 1X0NA 2C0OA 2DCRA 3BUNB 2ECDA 1BMBA 1KC2A 2FCIA 2K79B 1ZFPE 4F59A 1H9OA 1JYRA 5EHRA 1CWDL 1YVHA 1SPRA 2DX0A 5HKYA 1BFIA 2CI9A 3S8OA 3GXWA 1BHFA 2LQNA 1O4DA 4E93A 3S8LA 4H1OA 2XP1A 4ROJA 2IUIA 1XA6A 2CI8A 2H5KA 4XZ0A 1FBZA 1JYUA 1WQUA 5EELA 1BM2A 1QCFA 4DGPA 1A1AA 2PLEA 1X6CA 1NZVA 5AXIA 4K11A 2VIFA 5I6VA 1KA7A 1O4PA 1O46A 1A07A 2MRJA 3VRYA 3CBLA 1BLJA 2Y1MA 1AB2A 1O42A 2OQ1A 2EO3A 1SHAA 1KA6A 1AYBA 2HUWA 5DC4A 5IBMA 2K7AB 4L1BB 2RVFA 1A1EA 1Y57A 3CD3A 1HCTB 3EAZA 4GPLB 3BUOB 4EY0A 1OO4A 1FU5A 1Z3KA 3VRZA 1JYQA 3VGOA 3OB2B 1O4AA 2EL8A 1D1ZA 1UURA 2ABLA 2IUGA 3IN8A 4F5AA 3VS6A 3IMDA 3TKZA 1AYCA 1D4TA 1LKLA 4FL3A 1A1CA 2QMSA 1KSWA 3BUMB 4OHDA 2KK6A 1R1PA 3K2MA 5EEQA 2H46E 3IN7A 1LCKA 4X6SA 3S9KA 2FO0A 1LUNA 1JU5A 2LCTA 1TZEE 3VRPA 1GHUA 2MK2A 3QWYA 1M27A 3VRQA 1FMKA 3VROA 3UF4A 3HIZB 4P9ZA 2Y3AB 1MILA 3OB1B 5EG3B 4K2RA 3IMJA 2IUHA 2L6KA 5GJHA 1SHDA 1AD5A 1HCSB 4F5BA 4XZ1A 3S8NA 1O4IA 4A4CA 5J3XA 1A81A 1O44A 1OPKA 4U17A 1NRVA 1A08A 1BHHA 2RORA 4OHEA 2SHPA 2Y1NA 3PSKA 2GSBA 2CS0A 3PQZA 1NZLA 1PICA 1O49A 3QWXX 1X27A 1O4HA 3M7FA 1B47A 5HKZA 5DF6A 2DM0A 3VS2A 2BBUA 1SKJA 2MRKA 1IJRA 2YU7A 1BKLA 1TCEA 2CIAA 1BF5A 2MQIA 1JWOA 5EHPA 4DGXA 3PS5A 4LUDA 1GRIA 5DC0B 3OP0A 1O4QA 3VS7A 2DLYA 1O4RA 4A4BA 1D4WA 1LCJA 1O4KA 1O4JA 4JE4A 2KNOA 4H34A 3MAZA 2LQWA 1BG1A 1BFJA 4GL9E 5KAZA 3BUXB 2EYZA 1QG1E 2EO6A 2PLDA 1AYAA 1CSZA 2CR4A 1O48A 2HDVA 3PFVA 2C0TA 2EYYA 3GXXA 2MC1A 4FL2A 3N7YA 1K9AA 3C7IA 4EIHA 1M61A 1R1QA 4LUEA 2RSYA 2GE9A 2JYQA 5DC9A 2LNWA 4FBNA 3CXLA 1O4BA 5AULA 1FYRA 1O47A 1O4CA 3HHMB 1O41A 3N8MA 4K45A 4P9VA 3CWGA 1SPSA 1LUKA 2AOBA 3T04A 3PLFB 1RQQC 2HCKA 4TZIA 1O4EA 1LUMA 3N84A 2L4KA 1BLKA 3OVEA 1AOUF 3BKBA 1YVLA 1RJAA 2B3OA 2EU0A 1IS0A 1MW4A 2DVJA 3WA4A 1R1SA 5HKWA 5BO4A 3VS1A 1F1WA 2H8HA 5GJIA 5IBSA 1AOTF 1OPLA 1A1BA 3HCKA 1CJ1A 4K44A 3US4A 3PSJA 4GWFA 2IZVA 3BUWB 2C0IA 2AUGA 5D0JA 2LNXA 4U1PA 1O4GA 1I3ZA 2EKXA 2RMXA 3VS3A 2PNAA 2EOBA 4WWQA 3VRNA 1SHBA 3ZNIA 1FHSA 2PTKA 1A09A 2CBLA 1P13A 4OHIA 2AOAA 3UYOA 3MXYA 1F2FA 2YSXA 4OHLA 3MXCA 1O43A 5CDWA 2C9WA 4NWGA 3EACA 1Y1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CWE A;  1O45 A;  2ETZ A;  1O4L A;  1O4N A;  3KFJ A;  1BKM A;  4JGH A;  1G83 A;  2SRC A;  4OHH A;  1CSY A;  1LKK A;  1UUS A;  1AYD A;  1O4F A;  4JEG A;  2HMH A;  3TL0 A;  3VRR A;  4M4Z A;  4NWF A;  1QAD A;  2PNB A;  1FBV A;  1O4O A;  2HDX A;  4E68 A;  1RPY A;  2EYV A;  1FU6 A;  4QSY A;  1LUI A;  3PJP A;  3VS5 A;  2DLZ A;  1BHH B;  1O4M A;  4D8K A;  3VS0 A;  1OO3 A;  3VS4 A;  2OZO A;  2CRH A;  3GQI B;  3NHN A;  2L3T A;  3OV1 A;  1X0N A;  2C0O A;  2DCR A;  3BUN B;  2ECD A;  1BMB A;  1KC2 A;  2FCI A;  2K79 B;  1ZFP E;  4F59 A;  1H9O A;  1JYR A;  5EHR A;  1CWD L;  1YVH A;  1SPR A;  2DX0 A;  5HKY A;  1BFI A;  2CI9 A;  3S8O A;  3GXW A;  1BHF A;  2LQN A;  1O4D A;  4E93 A;  3S8L A;  4H1O A;  2XP1 A;  4ROJ A;  2IUI A;  1XA6 A;  2CI8 A;  2H5K A;  4XZ0 A;  1FBZ A;  1JYU A;  1WQU A;  5EEL A;  1BM2 A;  1QCF A;  4DGP A;  1A1A A;  2PLE A;  1X6C A;  1NZV A;  5AXI A;  4K11 A;  2VIF A;  5I6V A;  1KA7 A;  1O4P A;  1O46 A;  1A07 A;  2MRJ A;  3VRY A;  3CBL A;  1BLJ A;  2Y1M A;  1AB2 A;  1O42 A;  2OQ1 A;  2EO3 A;  1SHA A;  1KA6 A;  1AYB A;  2HUW A;  5DC4 A;  5IBM A;  2K7A B;  4L1B B;  2RVF A;  1A1E A;  1Y57 A;  3CD3 A;  1HCT B;  3EAZ A;  4GPL B;  3BUO B;  4EY0 A;  1OO4 A;  1FU5 A;  1Z3K A;  3VRZ A;  1JYQ A;  3VGO A;  3OB2 B;  1O4A A;  2EL8 A;  1D1Z A;  1UUR A;  2ABL A;  2IUG A;  3IN8 A;  4F5A A;  3VS6 A;  3IMD A;  3TKZ A;  1AYC A;  1D4T A;  1LKL A;  4FL3 A;  1A1C A;  2QMS A;  1KSW A;  3BUM B;  4OHD A;  2KK6 A;  1R1P A;  3K2M A;  5EEQ A;  2H46 E;  3IN7 A;  1LCK A;  4X6S A;  3S9K A;  2FO0 A;  1LUN A;  1JU5 A;  2LCT A;  1TZE E;  3VRP A;  1GHU A;  2MK2 A;  3QWY A;  1M27 A;  3VRQ A;  1FMK A;  3VRO A;  3UF4 A;  3HIZ B;  4P9Z A;  2Y3A B;  1MIL A;  3OB1 B;  5EG3 B;  4K2R A;  3IMJ A;  2IUH A;  2L6K A;  5GJH A;  1SHD A;  1AD5 A;  1HCS B;  4F5B A;  4XZ1 A;  3S8N A;  1O4I A;  4A4C A;  5J3X A;  1A81 A;  1O44 A;  1OPK A;  4U17 A;  1NRV A;  1A08 A;  1BHH A;  2ROR A;  4OHE A;  2SHP A;  2Y1N A;  3PSK A;  2GSB A;  2CS0 A;  3PQZ A;  1NZL A;  1PIC A;  1O49 A;  3QWX X;  1X27 A;  1O4H A;  3M7F A;  1B47 A;  5HKZ A;  5DF6 A;  2DM0 A;  3VS2 A;  2BBU A;  1SKJ A;  2MRK A;  1IJR A;  2YU7 A;  1BKL A;  1TCE A;  2CIA A;  1BF5 A;  2MQI A;  1JWO A;  5EHP A;  4DGX A;  3PS5 A;  4LUD A;  1GRI A;  5DC0 B;  3OP0 A;  1O4Q A;  3VS7 A;  2DLY A;  1O4R A;  4A4B A;  1D4W A;  1LCJ A;  1O4K A;  1O4J A;  4JE4 A;  2KNO A;  4H34 A;  3MAZ A;  2LQW A;  1BG1 A;  1BFJ A;  4GL9 E;  5KAZ A;  3BUX B;  2EYZ A;  1QG1 E;  2EO6 A;  2PLD A;  1AYA A;  1CSZ A;  2CR4 A;  1O48 A;  2HDV A;  3PFV A;  2C0T A;  2EYY A;  3GXX A;  2MC1 A;  4FL2 A;  3N7Y A;  1K9A A;  3C7I A;  4EIH A;  1M61 A;  1R1Q A;  4LUE A;  2RSY A;  2GE9 A;  2JYQ A;  5DC9 A;  2LNW A;  4FBN A;  3CXL A;  1O4B A;  5AUL A;  1FYR A;  1O47 A;  1O4C A;  3HHM B;  1O41 A;  3N8M A;  4K45 A;  4P9V A;  3CWG A;  1SPS A;  1LUK A;  2AOB A;  3T04 A;  3PLF B;  1RQQ C;  2HCK A;  4TZI A;  1O4E A;  1LUM A;  3N84 A;  2L4K A;  1BLK A;  3OVE A;  1AOU F;  3BKB A;  1YVL A;  1RJA A;  2B3O A;  2EU0 A;  1IS0 A;  1MW4 A;  2DVJ A;  3WA4 A;  1R1S A;  5HKW A;  5BO4 A;  3VS1 A;  1F1W A;  2H8H A;  5GJI A;  5IBS A;  1AOT F;  1OPL A;  1A1B A;  3HCK A;  1CJ1 A;  4K44 A;  3US4 A;  3PSJ A;  4GWF A;  2IZV A;  3BUW B;  2C0I A;  2AUG A;  5D0J A;  2LNX A;  4U1P A;  1O4G A;  1I3Z A;  2EKX A;  2RMX A;  3VS3 A;  2PNA A;  2EOB A;  4WWQ A;  3VRN A;  1SHB A;  3ZNI A;  1FHS A;  2PTK A;  1A09 A;  2CBL A;  1P13 A;  4OHI A;  2AOA A;  3UYO A;  3MXY A;  1F2F A;  2YSX A;  4OHL A;  3MXC A;  1O43 A;  5CDW A;  2C9W A;  4NWG A;  3EAC A;  1Y1U A; 
#chains in the Genus database with same CATH topology
 1CWE A;  1O45 A;  2ETZ A;  1O4L A;  1O4N A;  3KFJ A;  1BKM A;  4JGH A;  1G83 A;  2SRC A;  4OHH A;  1CSY A;  1LKK A;  1UUS A;  1AYD A;  1O4F A;  3K2T A;  4JEG A;  2HMH A;  3TL0 A;  3VRR A;  4M4Z A;  4NWF A;  1QAD A;  2PNB A;  1FBV A;  1O4O A;  2HDX A;  4E68 A;  1RPY A;  2EYV A;  1FU6 A;  4QSY A;  1LUI A;  3PJP A;  3VS5 A;  2DLZ A;  1BHH B;  1O4M A;  4D8K A;  3VS0 A;  1OO3 A;  3VS4 A;  2OZO A;  2CRH A;  3GQI B;  3NHN A;  2L3T A;  3OV1 A;  1X0N A;  2C0O A;  2DCR A;  3BUN B;  2ECD A;  1BMB A;  1KC2 A;  2FCI A;  2K79 B;  1ZFP E;  4F59 A;  1H9O A;  1JYR A;  5EHR A;  1CWD L;  1YVH A;  1SPR A;  2DX0 A;  5HKY A;  1BFI A;  2CI9 A;  3S8O A;  3GXW A;  1BHF A;  2LQN A;  1O4D A;  4E93 A;  3S8L A;  4H1O A;  2XP1 A;  4ROJ A;  2IUI A;  1XA6 A;  2CI8 A;  2H5K A;  4XZ0 A;  1FBZ A;  1JYU A;  1WQU A;  5EEL A;  1BM2 A;  1QCF A;  4DGP A;  1A1A A;  2PLE A;  1X6C A;  1NZV A;  5AXI A;  4K11 A;  2VIF A;  5I6V A;  1KA7 A;  1O4P A;  1O46 A;  1A07 A;  2MRJ A;  3VRY A;  3CBL A;  1BLJ A;  2Y1M A;  1AB2 A;  1O42 A;  2OQ1 A;  2EO3 A;  1SHA A;  1KA6 A;  1AYB A;  2HUW A;  5DC4 A;  5IBM A;  2K7A B;  4L1B B;  2RVF A;  1A1E A;  1Y57 A;  3CD3 A;  1HCT B;  3EAZ A;  4GPL B;  3BUO B;  4EY0 A;  1OO4 A;  1FU5 A;  1Z3K A;  3VRZ A;  1JYQ A;  3VGO A;  3OB2 B;  1O4A A;  2EL8 A;  1D1Z A;  1UUR A;  2ABL A;  2IUG A;  3IN8 A;  4F5A A;  3VS6 A;  3IMD A;  3TKZ A;  1AYC A;  1D4T A;  1LKL A;  4FL3 A;  1A1C A;  2QMS A;  1KSW A;  3BUM B;  4OHD A;  2KK6 A;  1R1P A;  3K2M A;  5EEQ A;  2H46 E;  3IN7 A;  1LCK A;  4X6S A;  3S9K A;  2FO0 A;  1LUN A;  1JU5 A;  2LCT A;  1TZE E;  3VRP A;  1GHU A;  2MK2 A;  3QWY A;  1M27 A;  3VRQ A;  1FMK A;  3VRO A;  3UF4 A;  3HIZ B;  4P9Z A;  2Y3A B;  1MIL A;  3OB1 B;  5EG3 B;  4K2R A;  3IMJ A;  2IUH A;  2L6K A;  5GJH A;  1SHD A;  1AD5 A;  1HCS B;  4F5B A;  4XZ1 A;  3S8N A;  1O4I A;  4A4C A;  5J3X A;  1A81 A;  1O44 A;  1OPK A;  4U17 A;  1NRV A;  1A08 A;  1BHH A;  2ROR A;  4OHE A;  2SHP A;  2Y1N A;  3PSK A;  2GSB A;  2CS0 A;  3PQZ A;  1NZL A;  1PIC A;  1O49 A;  3QWX X;  1X27 A;  1O4H A;  3M7F A;  1B47 A;  5HKZ A;  5DF6 A;  2DM0 A;  3VS2 A;  2BBU A;  1SKJ A;  2MRK A;  1IJR A;  2YU7 A;  1BKL A;  1TCE A;  2CIA A;  1BF5 A;  2MQI A;  1JWO A;  5EHP A;  4DGX A;  3PS5 A;  4LUD A;  1GRI A;  5DC0 B;  3OP0 A;  1O4Q A;  3VS7 A;  2DLY A;  1O4R A;  4A4B A;  1D4W A;  1LCJ A;  1O4K A;  1O4J A;  4JE4 A;  2KNO A;  4H34 A;  3MAZ A;  2LRA A;  2LQW A;  1BG1 A;  1BFJ A;  4GL9 E;  5KAZ A;  3BUX B;  2EYZ A;  1QG1 E;  2EO6 A;  2PLD A;  1AYA A;  1CSZ A;  2CR4 A;  1O48 A;  2HDV A;  3PFV A;  3LYV A;  2C0T A;  2EYY A;  3GXX A;  2MC1 A;  4FL2 A;  3N7Y A;  1K9A A;  3C7I A;  4EIH A;  1M61 A;  1R1Q A;  4LUE A;  2RSY A;  2GE9 A;  2JYQ A;  5DC9 A;  2LNW A;  4FBN A;  3CXL A;  1O4B A;  5AUL A;  1FYR A;  1O47 A;  1O4C A;  3HHM B;  1O41 A;  3N8M A;  4K45 A;  4P9V A;  3CWG A;  1SPS A;  1LUK A;  2AOB A;  3T04 A;  3PLF B;  1RQQ C;  2HCK A;  4TZI A;  1O4E A;  1LUM A;  3N84 A;  2L4K A;  1BLK A;  3OVE A;  1AOU F;  3BKB A;  1YVL A;  1RJA A;  2B3O A;  2EU0 A;  1IS0 A;  1MW4 A;  2DVJ A;  3WA4 A;  1R1S A;  5HKW A;  5BO4 A;  3VS1 A;  1F1W A;  2H8H A;  5GJI A;  5IBS A;  1AOT F;  1OPL A;  1A1B A;  3HCK A;  1CJ1 A;  4K44 A;  3US4 A;  3PSJ A;  4GWF A;  2IZV A;  3BUW B;  2C0I A;  2AUG A;  5D0J A;  2LNX A;  4U1P A;  1O4G A;  1I3Z A;  2EKX A;  2RMX A;  3VS3 A;  2PNA A;  2EOB A;  4WWQ A;  3VRN A;  1SHB A;  3ZNI A;  1FHS A;  2PTK A;  1A09 A;  2CBL A;  1P13 A;  4OHI A;  2AOA A;  3UYO A;  3MXY A;  1F2F A;  2YSX A;  4OHL A;  3MXC A;  1O43 A;  5CDW A;  2C9W A;  2KGY A;  4NWG A;  3EAC A;  1Y1U A; 
#chains in the Genus database with same CATH homology
 1CWE A;  1O45 A;  2ETZ A;  1O4L A;  1O4N A;  3KFJ A;  1BKM A;  4JGH A;  1G83 A;  2SRC A;  4OHH A;  1CSY A;  1LKK A;  1UUS A;  1AYD A;  1O4F A;  4JEG A;  2HMH A;  3TL0 A;  3VRR A;  4M4Z A;  4NWF A;  1QAD A;  2PNB A;  1FBV A;  1O4O A;  2HDX A;  4E68 A;  1RPY A;  2EYV A;  1FU6 A;  4QSY A;  1LUI A;  3PJP A;  3VS5 A;  2DLZ A;  1BHH B;  1O4M A;  4D8K A;  3VS0 A;  1OO3 A;  3VS4 A;  2OZO A;  2CRH A;  3GQI B;  3NHN A;  2L3T A;  3OV1 A;  1X0N A;  2C0O A;  2DCR A;  3BUN B;  2ECD A;  1BMB A;  1KC2 A;  2FCI A;  2K79 B;  1ZFP E;  4F59 A;  1H9O A;  1JYR A;  5EHR A;  1CWD L;  1YVH A;  1SPR A;  2DX0 A;  5HKY A;  1BFI A;  2CI9 A;  3S8O A;  3GXW A;  1BHF A;  2LQN A;  1O4D A;  4E93 A;  3S8L A;  4H1O A;  2XP1 A;  4ROJ A;  2IUI A;  1XA6 A;  2CI8 A;  2H5K A;  4XZ0 A;  1FBZ A;  1JYU A;  1WQU A;  5EEL A;  1BM2 A;  1QCF A;  4DGP A;  1A1A A;  2PLE A;  1X6C A;  1NZV A;  5AXI A;  4K11 A;  2VIF A;  5I6V A;  1KA7 A;  1O4P A;  1O46 A;  1A07 A;  2MRJ A;  3VRY A;  3CBL A;  1BLJ A;  2Y1M A;  1AB2 A;  1O42 A;  2OQ1 A;  2EO3 A;  1SHA A;  1KA6 A;  1AYB A;  2HUW A;  5DC4 A;  5IBM A;  2K7A B;  4L1B B;  2RVF A;  1A1E A;  1Y57 A;  3CD3 A;  1HCT B;  3EAZ A;  4GPL B;  3BUO B;  4EY0 A;  1OO4 A;  1FU5 A;  1Z3K A;  3VRZ A;  1JYQ A;  3VGO A;  3OB2 B;  1O4A A;  2EL8 A;  1D1Z A;  1UUR A;  2ABL A;  2IUG A;  3IN8 A;  4F5A A;  3VS6 A;  3IMD A;  3TKZ A;  1AYC A;  1D4T A;  1LKL A;  4FL3 A;  1A1C A;  2QMS A;  1KSW A;  3BUM B;  4OHD A;  2KK6 A;  1R1P A;  3K2M A;  5EEQ A;  2H46 E;  3IN7 A;  1LCK A;  4X6S A;  3S9K A;  2FO0 A;  1LUN A;  1JU5 A;  2LCT A;  1TZE E;  3VRP A;  1GHU A;  2MK2 A;  3QWY A;  1M27 A;  3VRQ A;  1FMK A;  3VRO A;  3UF4 A;  3HIZ B;  4P9Z A;  2Y3A B;  1MIL A;  3OB1 B;  5EG3 B;  4K2R A;  3IMJ A;  2IUH A;  2L6K A;  5GJH A;  1SHD A;  1AD5 A;  1HCS B;  4F5B A;  4XZ1 A;  3S8N A;  1O4I A;  4A4C A;  5J3X A;  1A81 A;  1O44 A;  1OPK A;  4U17 A;  1NRV A;  1A08 A;  1BHH A;  2ROR A;  4OHE A;  2SHP A;  2Y1N A;  3PSK A;  2GSB A;  2CS0 A;  3PQZ A;  1NZL A;  1PIC A;  1O49 A;  3QWX X;  1X27 A;  1O4H A;  3M7F A;  1B47 A;  5HKZ A;  5DF6 A;  2DM0 A;  3VS2 A;  2BBU A;  1SKJ A;  2MRK A;  1IJR A;  2YU7 A;  1BKL A;  1TCE A;  2CIA A;  1BF5 A;  2MQI A;  1JWO A;  5EHP A;  4DGX A;  3PS5 A;  4LUD A;  1GRI A;  5DC0 B;  3OP0 A;  1O4Q A;  3VS7 A;  2DLY A;  1O4R A;  4A4B A;  1D4W A;  1LCJ A;  1O4K A;  1O4J A;  4JE4 A;  2KNO A;  4H34 A;  3MAZ A;  2LQW A;  1BG1 A;  1BFJ A;  4GL9 E;  5KAZ A;  3BUX B;  2EYZ A;  1QG1 E;  2EO6 A;  2PLD A;  1AYA A;  1CSZ A;  2CR4 A;  1O48 A;  2HDV A;  3PFV A;  2C0T A;  2EYY A;  3GXX A;  2MC1 A;  4FL2 A;  3N7Y A;  1K9A A;  3C7I A;  4EIH A;  1M61 A;  1R1Q A;  4LUE A;  2RSY A;  2GE9 A;  2JYQ A;  5DC9 A;  2LNW A;  4FBN A;  3CXL A;  1O4B A;  5AUL A;  1FYR A;  1O47 A;  1O4C A;  3HHM B;  1O41 A;  3N8M A;  4K45 A;  4P9V A;  3CWG A;  1SPS A;  1LUK A;  2AOB A;  3T04 A;  3PLF B;  1RQQ C;  2HCK A;  4TZI A;  1O4E A;  1LUM A;  3N84 A;  2L4K A;  1BLK A;  3OVE A;  1AOU F;  3BKB A;  1YVL A;  1RJA A;  2B3O A;  2EU0 A;  1IS0 A;  1MW4 A;  2DVJ A;  3WA4 A;  1R1S A;  5HKW A;  5BO4 A;  3VS1 A;  1F1W A;  2H8H A;  5GJI A;  5IBS A;  1AOT F;  1OPL A;  1A1B A;  3HCK A;  1CJ1 A;  4K44 A;  3US4 A;  3PSJ A;  4GWF A;  2IZV A;  3BUW B;  2C0I A;  2AUG A;  5D0J A;  2LNX A;  4U1P A;  1O4G A;  1I3Z A;  2EKX A;  2RMX A;  3VS3 A;  2PNA A;  2EOB A;  4WWQ A;  3VRN A;  1SHB A;  3ZNI A;  1FHS A;  2PTK A;  1A09 A;  2CBL A;  1P13 A;  4OHI A;  2AOA A;  3UYO A;  3MXY A;  1F2F A;  2YSX A;  4OHL A;  3MXC A;  1O43 A;  5CDW A;  2C9W A;  4NWG A;  3EAC A;  1Y1U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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