3IN7A

Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-py-q-n-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
99
structure length
99
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein/peptide
source organism Homo sapiens
publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 99
sequence length 99
chains with identical sequence C
ec nomenclature
pdb deposition date 2009-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3in7A00
1PICA 4NWFA 2YU7A 1QCFA 2PLEA 3VRPA 1O4JA 2PNAA 2ECDA 1BHHA 1IJRA 2EO6A 3S8NA 3PSJA 5EHRA 1FU6A 1CJ1A 1SHBA 5GJHA 5KAZA 2EL8A 2CI8A 3OV1A 3PSKA 3VS4A 1LUNA 4U17A 3S9KA 3IN8A 1CWDL 2DX0A 1FHSA 4P9VA 1KC2A 3CXLA 2C0TA 1O4CA 2LQNA 1BLKA 3TKZA 5IBSA 1D1ZA 1FU5A 4F5BA 2CR4A 2FO0A 4L1BB 1SHAA 1NZVA 3PJPA 4OHLA 1YVLA 3VRZA 3N84A 2HDVA 1A07A 1D4WA 1AD5A 1AYCA 2HUWA 1JYUA 1UUSA 4D8KA 4P9ZA 2H46E 1F2FA 1O4FA 2PLDA 4K2RA 3IMJA 3VGOA 1CWEA 1O4BA 1BFIA 2HDXA 1A1AA 4OHEA 2AOBA 2C9WA 4JGHA 2DLZA 3UYOA 1JWOA 5CDWA 3PLFB 1AB2A 4LUEA 2LCTA 3TL0A 1YVHA 5EEQA 4EIHA 1LUKA 1A1BA 3VROA 1I3ZA 1D4TA 1TCEA 1UURA 3VS1A 5J3XA 2VIFA 1AOTF 4FL3A 5DC0B 1IS0A 5HKYA 1RJAA 1LKKA 3OB1B 2XP1A 1SPRA 5IBMA 3OP0A 2HCKA 2MC1A 1LUIA 3S8OA 3GQIB 1O4HA 1LCKA 4H34A 1M27A 2MK2A 5AULA 1FBVA 2L6KA 2GSBA 1RPYA 2DLYA 1R1QA 2B3OA 1HCTB 1XA6A 2K79B 2ABLA 2MRJA 2K7AB 2CI9A 4E68A 2PTKA 1ZFPE 3CWGA 1BFJA 4OHDA 3BUWB 3BKBA 4F5AA 3BUXB 5BO4A 2HMHA 3CD3A 1BHFA 1TZEE 2EYVA 1FYRA 4FBNA 1O4PA 2C0IA 1X27A 1SPSA 5DC4A 1NZLA 1A81A 2CS0A 1A1CA 2RMXA 3UF4A 1O4DA 3T04A 3N7YA 1O4LA 3M7FA 1O4RA 1O4KA 3BUMB 3MAZA 2DCRA 3PQZA 5I6VA 3VS0A 5DF6A 1JYQA 5EG3B 2EU0A 2Y1NA 3S8LA 1A09A 4DGXA 3NHNA 1LCJA 1O47A 2OQ1A 1F1WA 1O4MA 2SHPA 3VS5A 2GE9A 3EACA 2CIAA 3QWYA 2RSYA 1G83A 2JYQA 1BKLA 2KK6A 2RVFA 3BUOB 2IUGA 5GJIA 2L4KA 1BF5A 4U1PA 1BKMA 4NWGA 4ROJA 1LKLA 4GL9E 1O4NA 1OO4A 2ETZA 5AXIA 1O45A 2IUIA 2EO3A 3ZNIA 1O4QA 1O4IA 2PNBA 1X0NA 4OHHA 2Y3AB 4A4CA 1BG1A 1O49A 1O44A 4K11A 2H5KA 2LNWA 4DGPA 1MILA 2BBUA 2DVJA 4XZ0A 5DC9A 1A08A 3IN7A 4GWFA 5D0JA 4TZIA 5HKWA 4E93A 1LUMA 1O4EA 3HIZB 1H9OA 2CRHA 1HCSB 4LUDA 1SHDA 1FMKA 3C7IA 1JYRA 1QADA 2DM0A 3VRQA 1AYBA 2IZVA 3VS3A 1X6CA 1O4AA 3GXXA 3EAZA 2SRCA 1O46A 3VRYA 4OHIA 4K44A 2EOBA 1JU5A 1KSWA 1FBZA 2KNOA 4GPLB 2LQWA 1O4GA 1KA6A 4H1OA 3HCKA 5EELA 1OPKA 2AUGA 1WQUA 3MXYA 4JE4A 4A4BA 2LNXA 1O42A 3US4A 3GXWA 1BHHB 3VS2A 1BM2A 1O4OA 2FCIA 1OO3A 1Y1UA 1CSZA 4X6SA 5HKZA 2H8HA 3CBLA 4WWQA 3K2MA 1O43A 4XZ1A 1M61A 1OPLA 3VRNA 2MRKA 4EY0A 2Y1MA 1NRVA 2OZOA 3MXCA 4QSYA 2EYYA 1BLJA 3KFJA 4JEGA 1R1SA 1R1PA 1A1EA 1RQQC 1AYDA 3HHMB 4K45A 1SKJA 3VS7A 3PS5A 2CBLA 2MQIA 4M4ZA 3OB2B 5EHPA 2IUHA 1AOUF 1Z3KA 3IMDA 1Y57A 2EKXA 3QWXX 1K9AA 1GRIA 1O48A 3VRRA 1CSYA 4F59A 1GHUA 2QMSA 1MW4A 3BUNB 3OVEA 1KA7A 2RORA 3PFVA 1QG1E 2EYZA 1O41A 1BMBA 2YSXA 3N8MA 1P13A 3WA4A 1AYAA 2AOAA 1B47A 2C0OA 2L3TA 3VS6A 4FL2A
chains in the Genus database with same CATH superfamily
1PICA 4NWFA 2YU7A 1QCFA 2PLEA 3VRPA 1O4JA 2PNAA 2ECDA 1BHHA 1IJRA 2EO6A 3S8NA 3PSJA 5EHRA 1FU6A 1CJ1A 1SHBA 5GJHA 5KAZA 2EL8A 2CI8A 3OV1A 3PSKA 3VS4A 1LUNA 4U17A 3S9KA 3IN8A 1CWDL 2DX0A 1FHSA 4P9VA 1KC2A 3CXLA 2C0TA 1O4CA 2LQNA 1BLKA 3TKZA 5IBSA 1D1ZA 1FU5A 4F5BA 2CR4A 2FO0A 4L1BB 1SHAA 1NZVA 3PJPA 4OHLA 1YVLA 3VRZA 3N84A 2HDVA 1A07A 1D4WA 1AD5A 1AYCA 2HUWA 1JYUA 1UUSA 4D8KA 4P9ZA 2H46E 1F2FA 1O4FA 2PLDA 4K2RA 3IMJA 3VGOA 1CWEA 1O4BA 1BFIA 2HDXA 1A1AA 4OHEA 2AOBA 2C9WA 4JGHA 2DLZA 3UYOA 1JWOA 5CDWA 3PLFB 1AB2A 4LUEA 2LCTA 3TL0A 1YVHA 5EEQA 4EIHA 1LUKA 1A1BA 3VROA 1I3ZA 1D4TA 1TCEA 1UURA 3VS1A 5J3XA 2VIFA 1AOTF 4FL3A 5DC0B 1IS0A 5HKYA 1RJAA 1LKKA 3OB1B 2XP1A 1SPRA 5IBMA 3OP0A 2HCKA 2MC1A 1LUIA 3S8OA 3GQIB 1O4HA 1LCKA 4H34A 1M27A 2MK2A 5AULA 1FBVA 2L6KA 2GSBA 1RPYA 2DLYA 1R1QA 2B3OA 1HCTB 1XA6A 2K79B 2ABLA 2MRJA 2K7AB 2CI9A 4E68A 2PTKA 1ZFPE 3CWGA 1BFJA 3LYVA 4OHDA 3BUWB 3BKBA 4F5AA 3BUXB 5BO4A 2HMHA 3CD3A 1BHFA 1TZEE 2EYVA 1FYRA 4FBNA 3K2TA 1O4PA 2C0IA 1X27A 1SPSA 5DC4A 1NZLA 1A81A 2CS0A 1A1CA 2RMXA 3UF4A 1O4DA 3T04A 3N7YA 1O4LA 3M7FA 1O4RA 1O4KA 3BUMB 3MAZA 2DCRA 3PQZA 5I6VA 3VS0A 5DF6A 1JYQA 5EG3B 2EU0A 2Y1NA 3S8LA 1A09A 4DGXA 3NHNA 1LCJA 1O47A 2OQ1A 1F1WA 1O4MA 2SHPA 3VS5A 2GE9A 3EACA 2CIAA 3QWYA 2RSYA 1G83A 2JYQA 1BKLA 2KGYA 2KK6A 2RVFA 2IUGA 3BUOB 2L4KA 5GJIA 1BF5A 4U1PA 1BKMA 4NWGA 4ROJA 1LKLA 4GL9E 1O4NA 1OO4A 2ETZA 5AXIA 1O45A 2IUIA 2EO3A 3ZNIA 1O4QA 1O4IA 2PNBA 1X0NA 4OHHA 2LRAA 2Y3AB 4A4CA 1BG1A 1O49A 1O44A 4K11A 2H5KA 2LNWA 4DGPA 1MILA 2BBUA 2DVJA 4XZ0A 5DC9A 1A08A 3IN7A 4GWFA 5D0JA 4TZIA 5HKWA 4E93A 1LUMA 1O4EA 3HIZB 1H9OA 2CRHA 1HCSB 4LUDA 1SHDA 1FMKA 3C7IA 1JYRA 1QADA 2DM0A 3VRQA 1AYBA 2IZVA 3VS3A 1X6CA 1O4AA 3GXXA 3EAZA 2SRCA 1O46A 3VRYA 4OHIA 4K44A 2EOBA 1JU5A 1KSWA 1FBZA 2KNOA 4GPLB 2LQWA 1O4GA 1KA6A 4H1OA 3HCKA 5EELA 1OPKA 2AUGA 1WQUA 3MXYA 4JE4A 4A4BA 2LNXA 1O42A 3US4A 3GXWA 1BHHB 3VS2A 1BM2A 1O4OA 2FCIA 1OO3A 1Y1UA 1CSZA 4X6SA 5HKZA 2H8HA 3CBLA 4WWQA 3K2MA 1O43A 4XZ1A 1M61A 1OPLA 3VRNA 2MRKA 4EY0A 2Y1MA 1NRVA 2OZOA 3MXCA 4QSYA 2EYYA 1BLJA 3KFJA 4JEGA 1R1SA 1R1PA 1A1EA 1RQQC 1AYDA 3HHMB 4K45A 1SKJA 3VS7A 3PS5A 2CBLA 2MQIA 4M4ZA 3OB2B 5EHPA 2IUHA 1AOUF 1Z3KA 3IMDA 1Y57A 2EKXA 3QWXX 1K9AA 1GRIA 1O48A 3VRRA 1CSYA 4F59A 1GHUA 2QMSA 1MW4A 3BUNB 3OVEA 1KA7A 2RORA 3PFVA 1QG1E 2EYZA 1O41A 1BMBA 2YSXA 3N8MA 1P13A 3WA4A 1AYAA 2AOAA 1B47A 2C0OA 2L3TA 3VS6A 4FL2A
chains in the Genus database with same CATH topology
1PICA 4NWFA 2YU7A 1QCFA 2PLEA 3VRPA 1O4JA 2PNAA 2ECDA 1BHHA 1IJRA 2EO6A 3S8NA 3PSJA 5EHRA 1FU6A 1CJ1A 1SHBA 5GJHA 5KAZA 2EL8A 2CI8A 3OV1A 3PSKA 3VS4A 1LUNA 4U17A 3S9KA 3IN8A 1CWDL 2DX0A 1FHSA 4P9VA 1KC2A 3CXLA 2C0TA 1O4CA 2LQNA 1BLKA 3TKZA 5IBSA 1D1ZA 1FU5A 4F5BA 2CR4A 2FO0A 4L1BB 1SHAA 1NZVA 3PJPA 4OHLA 1YVLA 3VRZA 3N84A 2HDVA 1A07A 1D4WA 1AD5A 1AYCA 2HUWA 1JYUA 1UUSA 4D8KA 4P9ZA 2H46E 1F2FA 1O4FA 2PLDA 4K2RA 3IMJA 3VGOA 1CWEA 1O4BA 1BFIA 2HDXA 1A1AA 4OHEA 2AOBA 2C9WA 4JGHA 2DLZA 3UYOA 1JWOA 5CDWA 3PLFB 1AB2A 4LUEA 2LCTA 3TL0A 1YVHA 5EEQA 4EIHA 1LUKA 1A1BA 3VROA 1I3ZA 1D4TA 1TCEA 1UURA 3VS1A 5J3XA 2VIFA 1AOTF 4FL3A 5DC0B 1IS0A 5HKYA 1RJAA 1LKKA 3OB1B 2XP1A 1SPRA 5IBMA 3OP0A 2HCKA 2MC1A 1LUIA 3S8OA 3GQIB 1O4HA 1LCKA 4H34A 1M27A 2MK2A 5AULA 1FBVA 2L6KA 2GSBA 1RPYA 2DLYA 1R1QA 2B3OA 1HCTB 1XA6A 2K79B 2ABLA 2MRJA 2K7AB 2CI9A 4E68A 2PTKA 1ZFPE 3CWGA 1BFJA 4OHDA 3BUWB 3BKBA 4F5AA 3BUXB 5BO4A 2HMHA 3CD3A 1BHFA 1TZEE 2EYVA 1FYRA 4FBNA 1O4PA 2C0IA 1X27A 1SPSA 5DC4A 1NZLA 1A81A 2CS0A 1A1CA 2RMXA 3UF4A 1O4DA 3T04A 3N7YA 1O4LA 3M7FA 1O4RA 1O4KA 3BUMB 3MAZA 2DCRA 3PQZA 5I6VA 3VS0A 5DF6A 1JYQA 5EG3B 2EU0A 2Y1NA 3S8LA 1A09A 4DGXA 3NHNA 1LCJA 1O47A 2OQ1A 1F1WA 1O4MA 2SHPA 3VS5A 2GE9A 3EACA 2CIAA 3QWYA 2RSYA 1G83A 2JYQA 1BKLA 2KK6A 2RVFA 3BUOB 2IUGA 5GJIA 2L4KA 1BF5A 4U1PA 1BKMA 4NWGA 4ROJA 1LKLA 4GL9E 1O4NA 1OO4A 2ETZA 5AXIA 1O45A 2IUIA 2EO3A 3ZNIA 1O4QA 1O4IA 2PNBA 1X0NA 4OHHA 2Y3AB 4A4CA 1BG1A 1O49A 1O44A 4K11A 2H5KA 2LNWA 4DGPA 1MILA 2BBUA 2DVJA 4XZ0A 5DC9A 1A08A 3IN7A 4GWFA 5D0JA 4TZIA 5HKWA 4E93A 1LUMA 1O4EA 3HIZB 1H9OA 2CRHA 1HCSB 4LUDA 1SHDA 1FMKA 3C7IA 1JYRA 1QADA 2DM0A 3VRQA 1AYBA 2IZVA 3VS3A 1X6CA 1O4AA 3GXXA 3EAZA 2SRCA 1O46A 3VRYA 4OHIA 4K44A 2EOBA 1JU5A 1KSWA 1FBZA 2KNOA 4GPLB 2LQWA 1O4GA 1KA6A 4H1OA 3HCKA 5EELA 1OPKA 2AUGA 1WQUA 3MXYA 4JE4A 4A4BA 2LNXA 1O42A 3US4A 3GXWA 1BHHB 3VS2A 1BM2A 1O4OA 2FCIA 1OO3A 1Y1UA 1CSZA 4X6SA 5HKZA 2H8HA 3CBLA 4WWQA 3K2MA 1O43A 4XZ1A 1M61A 1OPLA 3VRNA 2MRKA 4EY0A 2Y1MA 1NRVA 2OZOA 3MXCA 4QSYA 2EYYA 1BLJA 3KFJA 4JEGA 1R1SA 1R1PA 1A1EA 1RQQC 1AYDA 3HHMB 4K45A 1SKJA 3VS7A 3PS5A 2CBLA 2MQIA 4M4ZA 3OB2B 5EHPA 2IUHA 1AOUF 1Z3KA 3IMDA 1Y57A 2EKXA 3QWXX 1K9AA 1GRIA 1O48A 3VRRA 1CSYA 4F59A 1GHUA 2QMSA 1MW4A 3BUNB 3OVEA 1KA7A 2RORA 3PFVA 1QG1E 2EYZA 1O41A 1BMBA 2YSXA 3N8MA 1P13A 3WA4A 1AYAA 2AOAA 1B47A 2C0OA 2L3TA 3VS6A 4FL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PIC A;  4NWF A;  2YU7 A;  1QCF A;  2PLE A;  3VRP A;  1O4J A;  2PNA A;  2ECD A;  1BHH A;  1IJR A;  2EO6 A;  3S8N A;  3PSJ A;  5EHR A;  1FU6 A;  1CJ1 A;  1SHB A;  5GJH A;  5KAZ A;  2EL8 A;  2CI8 A;  3OV1 A;  3PSK A;  3VS4 A;  1LUN A;  4U17 A;  3S9K A;  3IN8 A;  1CWD L;  2DX0 A;  1FHS A;  4P9V A;  1KC2 A;  3CXL A;  2C0T A;  1O4C A;  2LQN A;  1BLK A;  3TKZ A;  5IBS A;  1D1Z A;  1FU5 A;  4F5B A;  2CR4 A;  2FO0 A;  4L1B B;  1SHA A;  1NZV A;  3PJP A;  4OHL A;  1YVL A;  3VRZ A;  3N84 A;  2HDV A;  1A07 A;  1D4W A;  1AD5 A;  1AYC A;  2HUW A;  1JYU A;  1UUS A;  4D8K A;  4P9Z A;  2H46 E;  1F2F A;  1O4F A;  2PLD A;  4K2R A;  3IMJ A;  3VGO A;  1CWE A;  1O4B A;  1BFI A;  2HDX A;  1A1A A;  4OHE A;  2AOB A;  2C9W A;  4JGH A;  2DLZ A;  3UYO A;  1JWO A;  5CDW A;  3PLF B;  1AB2 A;  4LUE A;  2LCT A;  3TL0 A;  1YVH A;  5EEQ A;  4EIH A;  1LUK A;  1A1B A;  3VRO A;  1I3Z A;  1D4T A;  1TCE A;  1UUR A;  3VS1 A;  5J3X A;  2VIF A;  1AOT F;  4FL3 A;  5DC0 B;  1IS0 A;  5HKY A;  1RJA A;  1LKK A;  3OB1 B;  2XP1 A;  1SPR A;  5IBM A;  3OP0 A;  2HCK A;  2MC1 A;  1LUI A;  3S8O A;  3GQI B;  1O4H A;  1LCK A;  4H34 A;  1M27 A;  2MK2 A;  5AUL A;  1FBV A;  2L6K A;  2GSB A;  1RPY A;  2DLY A;  1R1Q A;  2B3O A;  1HCT B;  1XA6 A;  2K79 B;  2ABL A;  2MRJ A;  2K7A B;  2CI9 A;  4E68 A;  2PTK A;  1ZFP E;  3CWG A;  1BFJ A;  4OHD A;  3BUW B;  3BKB A;  4F5A A;  3BUX B;  5BO4 A;  2HMH A;  3CD3 A;  1BHF A;  1TZE E;  2EYV A;  1FYR A;  4FBN A;  1O4P A;  2C0I A;  1X27 A;  1SPS A;  5DC4 A;  1NZL A;  1A81 A;  2CS0 A;  1A1C A;  2RMX A;  3UF4 A;  1O4D A;  3T04 A;  3N7Y A;  1O4L A;  3M7F A;  1O4R A;  1O4K A;  3BUM B;  3MAZ A;  2DCR A;  3PQZ A;  5I6V A;  3VS0 A;  5DF6 A;  1JYQ A;  5EG3 B;  2EU0 A;  2Y1N A;  3S8L A;  1A09 A;  4DGX A;  3NHN A;  1LCJ A;  1O47 A;  2OQ1 A;  1F1W A;  1O4M A;  2SHP A;  3VS5 A;  2GE9 A;  3EAC A;  2CIA A;  3QWY A;  2RSY A;  1G83 A;  2JYQ A;  1BKL A;  2KK6 A;  2RVF A;  3BUO B;  2IUG A;  5GJI A;  2L4K A;  1BF5 A;  4U1P A;  1BKM A;  4NWG A;  4ROJ A;  1LKL A;  4GL9 E;  1O4N A;  1OO4 A;  2ETZ A;  5AXI A;  1O45 A;  2IUI A;  2EO3 A;  3ZNI A;  1O4Q A;  1O4I A;  2PNB A;  1X0N A;  4OHH A;  2Y3A B;  4A4C A;  1BG1 A;  1O49 A;  1O44 A;  4K11 A;  2H5K A;  2LNW A;  4DGP A;  1MIL A;  2BBU A;  2DVJ A;  4XZ0 A;  5DC9 A;  1A08 A;  3IN7 A;  4GWF A;  5D0J A;  4TZI A;  5HKW A;  4E93 A;  1LUM A;  1O4E A;  3HIZ B;  1H9O A;  2CRH A;  1HCS B;  4LUD A;  1SHD A;  1FMK A;  3C7I A;  1JYR A;  1QAD A;  2DM0 A;  3VRQ A;  1AYB A;  2IZV A;  3VS3 A;  1X6C A;  1O4A A;  3GXX A;  3EAZ A;  2SRC A;  1O46 A;  3VRY A;  4OHI A;  4K44 A;  2EOB A;  1JU5 A;  1KSW A;  1FBZ A;  2KNO A;  4GPL B;  2LQW A;  1O4G A;  1KA6 A;  4H1O A;  3HCK A;  5EEL A;  1OPK A;  2AUG A;  1WQU A;  3MXY A;  4JE4 A;  4A4B A;  2LNX A;  1O42 A;  3US4 A;  3GXW A;  1BHH B;  3VS2 A;  1BM2 A;  1O4O A;  2FCI A;  1OO3 A;  1Y1U A;  1CSZ A;  4X6S A;  5HKZ A;  2H8H A;  3CBL A;  4WWQ A;  3K2M A;  1O43 A;  4XZ1 A;  1M61 A;  1OPL A;  3VRN A;  2MRK A;  4EY0 A;  2Y1M A;  1NRV A;  2OZO A;  3MXC A;  4QSY A;  2EYY A;  1BLJ A;  3KFJ A;  4JEG A;  1R1S A;  1R1P A;  1A1E A;  1RQQ C;  1AYD A;  3HHM B;  4K45 A;  1SKJ A;  3VS7 A;  3PS5 A;  2CBL A;  2MQI A;  4M4Z A;  3OB2 B;  5EHP A;  2IUH A;  1AOU F;  1Z3K A;  3IMD A;  1Y57 A;  2EKX A;  3QWX X;  1K9A A;  1GRI A;  1O48 A;  3VRR A;  1CSY A;  4F59 A;  1GHU A;  2QMS A;  1MW4 A;  3BUN B;  3OVE A;  1KA7 A;  2ROR A;  3PFV A;  1QG1 E;  2EYZ A;  1O41 A;  1BMB A;  2YSX A;  3N8M A;  1P13 A;  3WA4 A;  1AYA A;  2AOA A;  1B47 A;  2C0O A;  2L3T A;  3VS6 A;  4FL2 A; 
#chains in the Genus database with same CATH topology
 1PIC A;  4NWF A;  2YU7 A;  1QCF A;  2PLE A;  3VRP A;  1O4J A;  2PNA A;  2ECD A;  1BHH A;  1IJR A;  2EO6 A;  3S8N A;  3PSJ A;  5EHR A;  1FU6 A;  1CJ1 A;  1SHB A;  5GJH A;  5KAZ A;  2EL8 A;  2CI8 A;  3OV1 A;  3PSK A;  3VS4 A;  1LUN A;  4U17 A;  3S9K A;  3IN8 A;  1CWD L;  2DX0 A;  1FHS A;  4P9V A;  1KC2 A;  3CXL A;  2C0T A;  1O4C A;  2LQN A;  1BLK A;  3TKZ A;  5IBS A;  1D1Z A;  1FU5 A;  4F5B A;  2CR4 A;  2FO0 A;  4L1B B;  1SHA A;  1NZV A;  3PJP A;  4OHL A;  1YVL A;  3VRZ A;  3N84 A;  2HDV A;  1A07 A;  1D4W A;  1AD5 A;  1AYC A;  2HUW A;  1JYU A;  1UUS A;  4D8K A;  4P9Z A;  2H46 E;  1F2F A;  1O4F A;  2PLD A;  4K2R A;  3IMJ A;  3VGO A;  1CWE A;  1O4B A;  1BFI A;  2HDX A;  1A1A A;  4OHE A;  2AOB A;  2C9W A;  4JGH A;  2DLZ A;  3UYO A;  1JWO A;  5CDW A;  3PLF B;  1AB2 A;  4LUE A;  2LCT A;  3TL0 A;  1YVH A;  5EEQ A;  4EIH A;  1LUK A;  1A1B A;  3VRO A;  1I3Z A;  1D4T A;  1TCE A;  1UUR A;  3VS1 A;  5J3X A;  2VIF A;  1AOT F;  4FL3 A;  5DC0 B;  1IS0 A;  5HKY A;  1RJA A;  1LKK A;  3OB1 B;  2XP1 A;  1SPR A;  5IBM A;  3OP0 A;  2HCK A;  2MC1 A;  1LUI A;  3S8O A;  3GQI B;  1O4H A;  1LCK A;  4H34 A;  1M27 A;  2MK2 A;  5AUL A;  1FBV A;  2L6K A;  2GSB A;  1RPY A;  2DLY A;  1R1Q A;  2B3O A;  1HCT B;  1XA6 A;  2K79 B;  2ABL A;  2MRJ A;  2K7A B;  2CI9 A;  4E68 A;  2PTK A;  1ZFP E;  3CWG A;  1BFJ A;  3LYV A;  4OHD A;  3BUW B;  3BKB A;  4F5A A;  3BUX B;  5BO4 A;  2HMH A;  3CD3 A;  1BHF A;  1TZE E;  2EYV A;  1FYR A;  4FBN A;  3K2T A;  1O4P A;  2C0I A;  1X27 A;  1SPS A;  5DC4 A;  1NZL A;  1A81 A;  2CS0 A;  1A1C A;  2RMX A;  3UF4 A;  1O4D A;  3T04 A;  3N7Y A;  1O4L A;  3M7F A;  1O4R A;  1O4K A;  3BUM B;  3MAZ A;  2DCR A;  3PQZ A;  5I6V A;  3VS0 A;  5DF6 A;  1JYQ A;  5EG3 B;  2EU0 A;  2Y1N A;  3S8L A;  1A09 A;  4DGX A;  3NHN A;  1LCJ A;  1O47 A;  2OQ1 A;  1F1W A;  1O4M A;  2SHP A;  3VS5 A;  2GE9 A;  3EAC A;  2CIA A;  3QWY A;  2RSY A;  1G83 A;  2JYQ A;  1BKL A;  2KGY A;  2KK6 A;  2RVF A;  2IUG A;  3BUO B;  2L4K A;  5GJI A;  1BF5 A;  4U1P A;  1BKM A;  4NWG A;  4ROJ A;  1LKL A;  4GL9 E;  1O4N A;  1OO4 A;  2ETZ A;  5AXI A;  1O45 A;  2IUI A;  2EO3 A;  3ZNI A;  1O4Q A;  1O4I A;  2PNB A;  1X0N A;  4OHH A;  2LRA A;  2Y3A B;  4A4C A;  1BG1 A;  1O49 A;  1O44 A;  4K11 A;  2H5K A;  2LNW A;  4DGP A;  1MIL A;  2BBU A;  2DVJ A;  4XZ0 A;  5DC9 A;  1A08 A;  3IN7 A;  4GWF A;  5D0J A;  4TZI A;  5HKW A;  4E93 A;  1LUM A;  1O4E A;  3HIZ B;  1H9O A;  2CRH A;  1HCS B;  4LUD A;  1SHD A;  1FMK A;  3C7I A;  1JYR A;  1QAD A;  2DM0 A;  3VRQ A;  1AYB A;  2IZV A;  3VS3 A;  1X6C A;  1O4A A;  3GXX A;  3EAZ A;  2SRC A;  1O46 A;  3VRY A;  4OHI A;  4K44 A;  2EOB A;  1JU5 A;  1KSW A;  1FBZ A;  2KNO A;  4GPL B;  2LQW A;  1O4G A;  1KA6 A;  4H1O A;  3HCK A;  5EEL A;  1OPK A;  2AUG A;  1WQU A;  3MXY A;  4JE4 A;  4A4B A;  2LNX A;  1O42 A;  3US4 A;  3GXW A;  1BHH B;  3VS2 A;  1BM2 A;  1O4O A;  2FCI A;  1OO3 A;  1Y1U A;  1CSZ A;  4X6S A;  5HKZ A;  2H8H A;  3CBL A;  4WWQ A;  3K2M A;  1O43 A;  4XZ1 A;  1M61 A;  1OPL A;  3VRN A;  2MRK A;  4EY0 A;  2Y1M A;  1NRV A;  2OZO A;  3MXC A;  4QSY A;  2EYY A;  1BLJ A;  3KFJ A;  4JEG A;  1R1S A;  1R1P A;  1A1E A;  1RQQ C;  1AYD A;  3HHM B;  4K45 A;  1SKJ A;  3VS7 A;  3PS5 A;  2CBL A;  2MQI A;  4M4Z A;  3OB2 B;  5EHP A;  2IUH A;  1AOU F;  1Z3K A;  3IMD A;  1Y57 A;  2EKX A;  3QWX X;  1K9A A;  1GRI A;  1O48 A;  3VRR A;  1CSY A;  4F59 A;  1GHU A;  2QMS A;  1MW4 A;  3BUN B;  3OVE A;  1KA7 A;  2ROR A;  3PFV A;  1QG1 E;  2EYZ A;  1O41 A;  1BMB A;  2YSX A;  3N8M A;  1P13 A;  3WA4 A;  1AYA A;  2AOA A;  1B47 A;  2C0O A;  2L3T A;  3VS6 A;  4FL2 A; 
#chains in the Genus database with same CATH homology
 1PIC A;  4NWF A;  2YU7 A;  1QCF A;  2PLE A;  3VRP A;  1O4J A;  2PNA A;  2ECD A;  1BHH A;  1IJR A;  2EO6 A;  3S8N A;  3PSJ A;  5EHR A;  1FU6 A;  1CJ1 A;  1SHB A;  5GJH A;  5KAZ A;  2EL8 A;  2CI8 A;  3OV1 A;  3PSK A;  3VS4 A;  1LUN A;  4U17 A;  3S9K A;  3IN8 A;  1CWD L;  2DX0 A;  1FHS A;  4P9V A;  1KC2 A;  3CXL A;  2C0T A;  1O4C A;  2LQN A;  1BLK A;  3TKZ A;  5IBS A;  1D1Z A;  1FU5 A;  4F5B A;  2CR4 A;  2FO0 A;  4L1B B;  1SHA A;  1NZV A;  3PJP A;  4OHL A;  1YVL A;  3VRZ A;  3N84 A;  2HDV A;  1A07 A;  1D4W A;  1AD5 A;  1AYC A;  2HUW A;  1JYU A;  1UUS A;  4D8K A;  4P9Z A;  2H46 E;  1F2F A;  1O4F A;  2PLD A;  4K2R A;  3IMJ A;  3VGO A;  1CWE A;  1O4B A;  1BFI A;  2HDX A;  1A1A A;  4OHE A;  2AOB A;  2C9W A;  4JGH A;  2DLZ A;  3UYO A;  1JWO A;  5CDW A;  3PLF B;  1AB2 A;  4LUE A;  2LCT A;  3TL0 A;  1YVH A;  5EEQ A;  4EIH A;  1LUK A;  1A1B A;  3VRO A;  1I3Z A;  1D4T A;  1TCE A;  1UUR A;  3VS1 A;  5J3X A;  2VIF A;  1AOT F;  4FL3 A;  5DC0 B;  1IS0 A;  5HKY A;  1RJA A;  1LKK A;  3OB1 B;  2XP1 A;  1SPR A;  5IBM A;  3OP0 A;  2HCK A;  2MC1 A;  1LUI A;  3S8O A;  3GQI B;  1O4H A;  1LCK A;  4H34 A;  1M27 A;  2MK2 A;  5AUL A;  1FBV A;  2L6K A;  2GSB A;  1RPY A;  2DLY A;  1R1Q A;  2B3O A;  1HCT B;  1XA6 A;  2K79 B;  2ABL A;  2MRJ A;  2K7A B;  2CI9 A;  4E68 A;  2PTK A;  1ZFP E;  3CWG A;  1BFJ A;  4OHD A;  3BUW B;  3BKB A;  4F5A A;  3BUX B;  5BO4 A;  2HMH A;  3CD3 A;  1BHF A;  1TZE E;  2EYV A;  1FYR A;  4FBN A;  1O4P A;  2C0I A;  1X27 A;  1SPS A;  5DC4 A;  1NZL A;  1A81 A;  2CS0 A;  1A1C A;  2RMX A;  3UF4 A;  1O4D A;  3T04 A;  3N7Y A;  1O4L A;  3M7F A;  1O4R A;  1O4K A;  3BUM B;  3MAZ A;  2DCR A;  3PQZ A;  5I6V A;  3VS0 A;  5DF6 A;  1JYQ A;  5EG3 B;  2EU0 A;  2Y1N A;  3S8L A;  1A09 A;  4DGX A;  3NHN A;  1LCJ A;  1O47 A;  2OQ1 A;  1F1W A;  1O4M A;  2SHP A;  3VS5 A;  2GE9 A;  3EAC A;  2CIA A;  3QWY A;  2RSY A;  1G83 A;  2JYQ A;  1BKL A;  2KK6 A;  2RVF A;  3BUO B;  2IUG A;  5GJI A;  2L4K A;  1BF5 A;  4U1P A;  1BKM A;  4NWG A;  4ROJ A;  1LKL A;  4GL9 E;  1O4N A;  1OO4 A;  2ETZ A;  5AXI A;  1O45 A;  2IUI A;  2EO3 A;  3ZNI A;  1O4Q A;  1O4I A;  2PNB A;  1X0N A;  4OHH A;  2Y3A B;  4A4C A;  1BG1 A;  1O49 A;  1O44 A;  4K11 A;  2H5K A;  2LNW A;  4DGP A;  1MIL A;  2BBU A;  2DVJ A;  4XZ0 A;  5DC9 A;  1A08 A;  3IN7 A;  4GWF A;  5D0J A;  4TZI A;  5HKW A;  4E93 A;  1LUM A;  1O4E A;  3HIZ B;  1H9O A;  2CRH A;  1HCS B;  4LUD A;  1SHD A;  1FMK A;  3C7I A;  1JYR A;  1QAD A;  2DM0 A;  3VRQ A;  1AYB A;  2IZV A;  3VS3 A;  1X6C A;  1O4A A;  3GXX A;  3EAZ A;  2SRC A;  1O46 A;  3VRY A;  4OHI A;  4K44 A;  2EOB A;  1JU5 A;  1KSW A;  1FBZ A;  2KNO A;  4GPL B;  2LQW A;  1O4G A;  1KA6 A;  4H1O A;  3HCK A;  5EEL A;  1OPK A;  2AUG A;  1WQU A;  3MXY A;  4JE4 A;  4A4B A;  2LNX A;  1O42 A;  3US4 A;  3GXW A;  1BHH B;  3VS2 A;  1BM2 A;  1O4O A;  2FCI A;  1OO3 A;  1Y1U A;  1CSZ A;  4X6S A;  5HKZ A;  2H8H A;  3CBL A;  4WWQ A;  3K2M A;  1O43 A;  4XZ1 A;  1M61 A;  1OPL A;  3VRN A;  2MRK A;  4EY0 A;  2Y1M A;  1NRV A;  2OZO A;  3MXC A;  4QSY A;  2EYY A;  1BLJ A;  3KFJ A;  4JEG A;  1R1S A;  1R1P A;  1A1E A;  1RQQ C;  1AYD A;  3HHM B;  4K45 A;  1SKJ A;  3VS7 A;  3PS5 A;  2CBL A;  2MQI A;  4M4Z A;  3OB2 B;  5EHP A;  2IUH A;  1AOU F;  1Z3K A;  3IMD A;  1Y57 A;  2EKX A;  3QWX X;  1K9A A;  1GRI A;  1O48 A;  3VRR A;  1CSY A;  4F59 A;  1GHU A;  2QMS A;  1MW4 A;  3BUN B;  3OVE A;  1KA7 A;  2ROR A;  3PFV A;  1QG1 E;  2EYZ A;  1O41 A;  1BMB A;  2YSX A;  3N8M A;  1P13 A;  3WA4 A;  1AYA A;  2AOA A;  1B47 A;  2C0O A;  2L3T A;  3VS6 A;  4FL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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