3MXCA

Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications.
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2010-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3mxcA00
3UYOA 2LQWA 5D0JA 3T04A 3CBLA 1LUIA 2C9WA 2Y3AB 4GL9E 3OP0A 4XZ1A 1NZLA 2LNWA 1IJRA 3IN7A 2RVFA 5EHRA 1BHFA 2ABLA 3GXWA 1OO3A 4WWQA 1D4TA 1KC2A 3MXCA 2BBUA 2L3TA 2PNAA 2JYQA 1AYDA 5DC4A 1BMBA 5BO4A 4A4BA 2H8HA 2MK2A 3PS5A 5IBMA 1QG1E 4DGPA 3PJPA 1O4IA 2KK6A 5HKWA 3S9KA 2AOAA 2LQNA 1I3ZA 1R1QA 1A1CA 3TL0A 1D1ZA 1BHHB 1GRIA 2GE9A 4K11A 3N84A 3UF4A 3HCKA 1FBZA 1AOUF 2MC1A 1A1AA 1M61A 4XZ0A 1O42A 3BUOB 1HCSB 1AD5A 1RQQC 1QCFA 1JU5A 3QWXX 1GHUA 4E68A 2RORA 1X0NA 1FBVA 2PLDA 1BFJA 4EY0A 1NRVA 1BF5A 4K45A 2L6KA 1Y57A 1O4BA 3K2MA 3PQZA 3EAZA 1BLJA 1O44A 5KAZA 2LCTA 1LCKA 1O4MA 4TZIA 2K79B 4GPLB 5DF6A 2EYYA 4FL3A 4JGHA 4QSYA 1SPSA 2IUGA 1BHHA 1F1WA 1BLKA 2MRKA 3VS0A 3N8MA 1YVLA 3VS1A 1MILA 1A1BA 1O4OA 4LUDA 3VRYA 2PTKA 2YU7A 1O43A 4U17A 4A4CA 2DCRA 1A09A 2DX0A 3MAZA 5AULA 4OHLA 2PLEA 1IS0A 4OHEA 1JYUA 1CWEA 3MXYA 1CSYA 1M27A 3HHMB 2SRCA 1A1EA 3BUWB 5J3XA 3VRRA 4H1OA 2ETZA 1G83A 2AOBA 4LUEA 1SHBA 3OB1B 1HCTB 3VROA 2EL8A 1TCEA 1H9OA 3CWGA 4GWFA 4P9ZA 3TKZA 3BUNB 3WA4A 1A81A 5DC0B 2EOBA 2MQIA 3VS4A 5AXIA 3GQIB 1O4GA 3VS3A 1AOTF 1LKKA 3OVEA 3S8LA 1R1SA 4EIHA 5EEQA 1FMKA 1O41A 3QWYA 4P9VA 3S8NA 2C0TA 2IUHA 1O4JA 1O4HA 3S8OA 2HDXA 2CR4A 1X6CA 1O4DA 3N7YA 1JYQA 1FU6A 4K2RA 2EYVA 4ROJA 4K44A 2RMXA 1FHSA 3BUXB 2EKXA 4JE4A 1O4CA 1JYRA 2OZOA 4NWGA 2C0IA 2HMHA 1OPLA 2HDVA 1SKJA 2MRJA 3OV1A 2Y1MA 1O4AA 3VS2A 1O48A 1R1PA 1A07A 3BUMB 3VS6A 1BFIA 1Z3KA 3PSKA 1SPRA 3VGOA 1PICA 2HUWA 2KNOA 1KA7A 4D8KA 1FYRA 2SHPA 2DLZA 5IBSA 3PLFB 1OO4A 2FCIA 1UUSA 3VRPA 2YSXA 5EHPA 3ZNIA 2QMSA 1AYAA 2PNBA 5HKZA 4X6SA 2CS0A 4F5BA 2FO0A 3BKBA 2VIFA 2IUIA 3HIZB 1X27A 1O4PA 2EO6A 2CIAA 1JWOA 2IZVA 4H34A 1WQUA 2ECDA 3KFJA 2OQ1A 3GXXA 1F2FA 1UURA 4U1PA 1D4WA 2GSBA 2EO3A 2DVJA 2B3OA 3CD3A 2XP1A 3US4A 3VRQA 5EG3B 2CI9A 4F5AA 1RPYA 1O46A 3VS5A 2DLYA 1O4KA 4OHIA 3VRNA 1A08A 1CJ1A 3C7IA 3M7FA 1SHAA 3NHNA 2H46E 1RJAA 3OB2B 1CWDL 2AUGA 3IN8A 1K9AA 2L4KA 1SHDA 3PSJA 2LNXA 4FBNA 3PFVA 3IMJA 1OPKA 3VRZA 1XA6A 1Y1UA 1LKLA 1BKMA 5DC9A 1O4EA 2K7AB 2DM0A 1LCJA 1P13A 1AYCA 1TZEE 3IMDA 1O4QA 4OHDA 1FU5A 1O4RA 2HCKA 1B47A 2RSYA 4JEGA 4FL2A 2C0OA 4DGXA 1O45A 1YVHA 4F59A 1O47A 1ZFPE 1BM2A 5GJIA 2EYZA 1AYBA 5GJHA 3EACA 1BG1A 2CRHA 1MW4A 1BKLA 1O49A 1AB2A 1QADA 1LUMA 2H5KA 3CXLA 4E93A 4NWFA 1O4NA 5CDWA 2CBLA 2EU0A 1NZVA 4OHHA 2CI8A 5HKYA 1LUKA 5I6VA 1LUNA 2Y1NA 4L1BB 3VS7A 5EELA 1KSWA 4M4ZA 1O4LA 1O4FA 1KA6A 1CSZA
chains in the Genus database with same CATH superfamily
3UYOA 2LQWA 5D0JA 3T04A 3CBLA 2KGYA 1LUIA 2C9WA 2Y3AB 4GL9E 3OP0A 1NZLA 4XZ1A 2LNWA 1IJRA 3IN7A 2RVFA 5EHRA 1BHFA 2ABLA 3GXWA 1OO3A 4WWQA 1D4TA 1KC2A 3MXCA 2BBUA 2L3TA 2PNAA 2JYQA 1AYDA 5DC4A 1BMBA 5BO4A 4A4BA 2H8HA 2MK2A 3PS5A 5IBMA 1QG1E 4DGPA 3PJPA 1O4IA 2KK6A 5HKWA 3S9KA 2AOAA 2LQNA 1I3ZA 1R1QA 1A1CA 3TL0A 1D1ZA 1BHHB 1GRIA 2GE9A 4K11A 3N84A 3UF4A 3HCKA 1FBZA 1AOUF 2MC1A 1A1AA 1M61A 4XZ0A 1O42A 3BUOB 1HCSB 1AD5A 1RQQC 1QCFA 1JU5A 3QWXX 1GHUA 4E68A 2RORA 1X0NA 1FBVA 2PLDA 1BFJA 4EY0A 1NRVA 1BF5A 4K45A 2L6KA 1Y57A 1O4BA 3K2MA 3PQZA 3EAZA 1BLJA 1O44A 5KAZA 2LCTA 1LCKA 1O4MA 4TZIA 2K79B 4GPLB 5DF6A 2EYYA 4FL3A 4JGHA 4QSYA 1SPSA 2IUGA 1BHHA 1F1WA 1BLKA 2MRKA 3VS0A 3N8MA 1YVLA 3VS1A 1MILA 1A1BA 1O4OA 4LUDA 3VRYA 2PTKA 2YU7A 1O43A 4U17A 4A4CA 2DCRA 1A09A 2DX0A 3MAZA 5AULA 4OHLA 2PLEA 1IS0A 4OHEA 1JYUA 1CWEA 3MXYA 1CSYA 1M27A 3HHMB 2SRCA 1A1EA 3BUWB 5J3XA 3VRRA 4H1OA 2ETZA 1G83A 2AOBA 4LUEA 1SHBA 3OB1B 1HCTB 3VROA 2EL8A 1TCEA 1H9OA 2LRAA 3CWGA 4GWFA 4P9ZA 3TKZA 3BUNB 3WA4A 1A81A 5DC0B 2EOBA 2MQIA 3VS4A 5AXIA 3GQIB 1O4GA 3VS3A 1AOTF 1LKKA 3OVEA 3S8LA 1R1SA 4EIHA 5EEQA 1FMKA 1O41A 3QWYA 4P9VA 3S8NA 2C0TA 2IUHA 1O4JA 1O4HA 3S8OA 2HDXA 2CR4A 1X6CA 1O4DA 3N7YA 1JYQA 1FU6A 4K2RA 2EYVA 3LYVA 4ROJA 4K44A 2RMXA 1FHSA 3BUXB 2EKXA 4JE4A 1O4CA 3K2TA 1JYRA 2OZOA 4NWGA 2C0IA 2HMHA 1OPLA 2HDVA 1SKJA 2MRJA 3OV1A 2Y1MA 1O4AA 3VS2A 1O48A 1R1PA 1A07A 3BUMB 3VS6A 1BFIA 1Z3KA 3PSKA 1SPRA 3VGOA 1PICA 2HUWA 2KNOA 1KA7A 4D8KA 1FYRA 2SHPA 2DLZA 5IBSA 3PLFB 1OO4A 2FCIA 1UUSA 3VRPA 2YSXA 5EHPA 3ZNIA 2QMSA 1AYAA 2PNBA 5HKZA 4X6SA 2CS0A 4F5BA 2FO0A 3BKBA 2VIFA 2IUIA 3HIZB 1X27A 1O4PA 2EO6A 2CIAA 1JWOA 2IZVA 4H34A 1WQUA 2ECDA 3KFJA 2OQ1A 3GXXA 1F2FA 1UURA 4U1PA 1D4WA 2GSBA 2EO3A 2DVJA 2B3OA 3CD3A 2XP1A 3US4A 3VRQA 5EG3B 2CI9A 4F5AA 1RPYA 1O46A 3VS5A 2DLYA 1O4KA 4OHIA 3VRNA 1A08A 1CJ1A 3C7IA 3M7FA 1SHAA 3NHNA 2H46E 1RJAA 3OB2B 1CWDL 2AUGA 3IN8A 1K9AA 2L4KA 1SHDA 3PSJA 2LNXA 4FBNA 3PFVA 3IMJA 1OPKA 3VRZA 1XA6A 1Y1UA 1LKLA 1BKMA 5DC9A 1O4EA 2K7AB 2DM0A 1LCJA 1P13A 1AYCA 1TZEE 3IMDA 1O4QA 4OHDA 1FU5A 1O4RA 2HCKA 1B47A 2RSYA 4JEGA 4FL2A 2C0OA 4DGXA 1O45A 1YVHA 4F59A 1O47A 1ZFPE 1BM2A 5GJIA 2EYZA 1AYBA 5GJHA 3EACA 1BG1A 2CRHA 1MW4A 1BKLA 1O49A 1AB2A 1QADA 1LUMA 2H5KA 3CXLA 4E93A 4NWFA 1O4NA 5CDWA 2CBLA 2EU0A 1NZVA 4OHHA 2CI8A 5HKYA 1LUKA 5I6VA 1LUNA 2Y1NA 4L1BB 3VS7A 5EELA 1KSWA 4M4ZA 1O4LA 1O4FA 1KA6A 1CSZA
chains in the Genus database with same CATH topology
3UYOA 2LQWA 5D0JA 3T04A 3CBLA 1LUIA 2C9WA 2Y3AB 4GL9E 3OP0A 4XZ1A 1NZLA 2LNWA 1IJRA 3IN7A 2RVFA 5EHRA 1BHFA 2ABLA 3GXWA 1OO3A 4WWQA 1D4TA 1KC2A 3MXCA 2BBUA 2L3TA 2PNAA 2JYQA 1AYDA 5DC4A 1BMBA 5BO4A 4A4BA 2H8HA 2MK2A 3PS5A 5IBMA 1QG1E 4DGPA 3PJPA 1O4IA 2KK6A 5HKWA 3S9KA 2AOAA 2LQNA 1I3ZA 1R1QA 1A1CA 3TL0A 1D1ZA 1BHHB 1GRIA 2GE9A 4K11A 3N84A 3UF4A 3HCKA 1FBZA 1AOUF 2MC1A 1A1AA 1M61A 4XZ0A 1O42A 3BUOB 1HCSB 1AD5A 1RQQC 1QCFA 1JU5A 3QWXX 1GHUA 4E68A 2RORA 1X0NA 1FBVA 2PLDA 1BFJA 4EY0A 1NRVA 1BF5A 4K45A 2L6KA 1Y57A 1O4BA 3K2MA 3PQZA 3EAZA 1BLJA 1O44A 5KAZA 2LCTA 1LCKA 1O4MA 4TZIA 2K79B 4GPLB 5DF6A 2EYYA 4FL3A 4JGHA 4QSYA 1SPSA 2IUGA 1BHHA 1F1WA 1BLKA 2MRKA 3VS0A 3N8MA 1YVLA 3VS1A 1MILA 1A1BA 1O4OA 4LUDA 3VRYA 2PTKA 2YU7A 1O43A 4U17A 4A4CA 2DCRA 1A09A 2DX0A 3MAZA 5AULA 4OHLA 2PLEA 1IS0A 4OHEA 1JYUA 1CWEA 3MXYA 1CSYA 1M27A 3HHMB 2SRCA 1A1EA 3BUWB 5J3XA 3VRRA 4H1OA 2ETZA 1G83A 2AOBA 4LUEA 1SHBA 3OB1B 1HCTB 3VROA 2EL8A 1TCEA 1H9OA 3CWGA 4GWFA 4P9ZA 3TKZA 3BUNB 3WA4A 1A81A 5DC0B 2EOBA 2MQIA 3VS4A 5AXIA 3GQIB 1O4GA 3VS3A 1AOTF 1LKKA 3OVEA 3S8LA 1R1SA 4EIHA 5EEQA 1FMKA 1O41A 3QWYA 4P9VA 3S8NA 2C0TA 2IUHA 1O4JA 1O4HA 3S8OA 2HDXA 2CR4A 1X6CA 1O4DA 3N7YA 1JYQA 1FU6A 4K2RA 2EYVA 4ROJA 4K44A 2RMXA 1FHSA 3BUXB 2EKXA 4JE4A 1O4CA 1JYRA 2OZOA 4NWGA 2C0IA 2HMHA 1OPLA 2HDVA 1SKJA 2MRJA 3OV1A 2Y1MA 1O4AA 3VS2A 1O48A 1R1PA 1A07A 3BUMB 3VS6A 1BFIA 1Z3KA 3PSKA 1SPRA 3VGOA 1PICA 2HUWA 2KNOA 1KA7A 4D8KA 1FYRA 2SHPA 2DLZA 5IBSA 3PLFB 1OO4A 2FCIA 1UUSA 3VRPA 2YSXA 5EHPA 3ZNIA 2QMSA 1AYAA 2PNBA 5HKZA 4X6SA 2CS0A 4F5BA 2FO0A 3BKBA 2VIFA 2IUIA 3HIZB 1X27A 1O4PA 2EO6A 2CIAA 1JWOA 2IZVA 4H34A 1WQUA 2ECDA 3KFJA 2OQ1A 3GXXA 1F2FA 1UURA 4U1PA 1D4WA 2GSBA 2EO3A 2DVJA 2B3OA 3CD3A 2XP1A 3US4A 3VRQA 5EG3B 2CI9A 4F5AA 1RPYA 1O46A 3VS5A 2DLYA 1O4KA 4OHIA 3VRNA 1A08A 1CJ1A 3C7IA 3M7FA 1SHAA 3NHNA 2H46E 1RJAA 3OB2B 1CWDL 2AUGA 3IN8A 1K9AA 2L4KA 1SHDA 3PSJA 2LNXA 4FBNA 3PFVA 3IMJA 1OPKA 3VRZA 1XA6A 1Y1UA 1LKLA 1BKMA 5DC9A 1O4EA 2K7AB 2DM0A 1LCJA 1P13A 1AYCA 1TZEE 3IMDA 1O4QA 4OHDA 1FU5A 1O4RA 2HCKA 1B47A 2RSYA 4JEGA 4FL2A 2C0OA 4DGXA 1O45A 1YVHA 4F59A 1O47A 1ZFPE 1BM2A 5GJIA 2EYZA 1AYBA 5GJHA 3EACA 1BG1A 2CRHA 1MW4A 1BKLA 1O49A 1AB2A 1QADA 1LUMA 2H5KA 3CXLA 4E93A 4NWFA 1O4NA 5CDWA 2CBLA 2EU0A 1NZVA 4OHHA 2CI8A 5HKYA 1LUKA 5I6VA 1LUNA 2Y1NA 4L1BB 3VS7A 5EELA 1KSWA 4M4ZA 1O4LA 1O4FA 1KA6A 1CSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UYO A;  2LQW A;  5D0J A;  3T04 A;  3CBL A;  1LUI A;  2C9W A;  2Y3A B;  4GL9 E;  3OP0 A;  4XZ1 A;  1NZL A;  2LNW A;  1IJR A;  3IN7 A;  2RVF A;  5EHR A;  1BHF A;  2ABL A;  3GXW A;  1OO3 A;  4WWQ A;  1D4T A;  1KC2 A;  3MXC A;  2BBU A;  2L3T A;  2PNA A;  2JYQ A;  1AYD A;  5DC4 A;  1BMB A;  5BO4 A;  4A4B A;  2H8H A;  2MK2 A;  3PS5 A;  5IBM A;  1QG1 E;  4DGP A;  3PJP A;  1O4I A;  2KK6 A;  5HKW A;  3S9K A;  2AOA A;  2LQN A;  1I3Z A;  1R1Q A;  1A1C A;  3TL0 A;  1D1Z A;  1BHH B;  1GRI A;  2GE9 A;  4K11 A;  3N84 A;  3UF4 A;  3HCK A;  1FBZ A;  1AOU F;  2MC1 A;  1A1A A;  1M61 A;  4XZ0 A;  1O42 A;  3BUO B;  1HCS B;  1AD5 A;  1RQQ C;  1QCF A;  1JU5 A;  3QWX X;  1GHU A;  4E68 A;  2ROR A;  1X0N A;  1FBV A;  2PLD A;  1BFJ A;  4EY0 A;  1NRV A;  1BF5 A;  4K45 A;  2L6K A;  1Y57 A;  1O4B A;  3K2M A;  3PQZ A;  3EAZ A;  1BLJ A;  1O44 A;  5KAZ A;  2LCT A;  1LCK A;  1O4M A;  4TZI A;  2K79 B;  4GPL B;  5DF6 A;  2EYY A;  4FL3 A;  4JGH A;  4QSY A;  1SPS A;  2IUG A;  1BHH A;  1F1W A;  1BLK A;  2MRK A;  3VS0 A;  3N8M A;  1YVL A;  3VS1 A;  1MIL A;  1A1B A;  1O4O A;  4LUD A;  3VRY A;  2PTK A;  2YU7 A;  1O43 A;  4U17 A;  4A4C A;  2DCR A;  1A09 A;  2DX0 A;  3MAZ A;  5AUL A;  4OHL A;  2PLE A;  1IS0 A;  4OHE A;  1JYU A;  1CWE A;  3MXY A;  1CSY A;  1M27 A;  3HHM B;  2SRC A;  1A1E A;  3BUW B;  5J3X A;  3VRR A;  4H1O A;  2ETZ A;  1G83 A;  2AOB A;  4LUE A;  1SHB A;  3OB1 B;  1HCT B;  3VRO A;  2EL8 A;  1TCE A;  1H9O A;  3CWG A;  4GWF A;  4P9Z A;  3TKZ A;  3BUN B;  3WA4 A;  1A81 A;  5DC0 B;  2EOB A;  2MQI A;  3VS4 A;  5AXI A;  3GQI B;  1O4G A;  3VS3 A;  1AOT F;  1LKK A;  3OVE A;  3S8L A;  1R1S A;  4EIH A;  5EEQ A;  1FMK A;  1O41 A;  3QWY A;  4P9V A;  3S8N A;  2C0T A;  2IUH A;  1O4J A;  1O4H A;  3S8O A;  2HDX A;  2CR4 A;  1X6C A;  1O4D A;  3N7Y A;  1JYQ A;  1FU6 A;  4K2R A;  2EYV A;  4ROJ A;  4K44 A;  2RMX A;  1FHS A;  3BUX B;  2EKX A;  4JE4 A;  1O4C A;  1JYR A;  2OZO A;  4NWG A;  2C0I A;  2HMH A;  1OPL A;  2HDV A;  1SKJ A;  2MRJ A;  3OV1 A;  2Y1M A;  1O4A A;  3VS2 A;  1O48 A;  1R1P A;  1A07 A;  3BUM B;  3VS6 A;  1BFI A;  1Z3K A;  3PSK A;  1SPR A;  3VGO A;  1PIC A;  2HUW A;  2KNO A;  1KA7 A;  4D8K A;  1FYR A;  2SHP A;  2DLZ A;  5IBS A;  3PLF B;  1OO4 A;  2FCI A;  1UUS A;  3VRP A;  2YSX A;  5EHP A;  3ZNI A;  2QMS A;  1AYA A;  2PNB A;  5HKZ A;  4X6S A;  2CS0 A;  4F5B A;  2FO0 A;  3BKB A;  2VIF A;  2IUI A;  3HIZ B;  1X27 A;  1O4P A;  2EO6 A;  2CIA A;  1JWO A;  2IZV A;  4H34 A;  1WQU A;  2ECD A;  3KFJ A;  2OQ1 A;  3GXX A;  1F2F A;  1UUR A;  4U1P A;  1D4W A;  2GSB A;  2EO3 A;  2DVJ A;  2B3O A;  3CD3 A;  2XP1 A;  3US4 A;  3VRQ A;  5EG3 B;  2CI9 A;  4F5A A;  1RPY A;  1O46 A;  3VS5 A;  2DLY A;  1O4K A;  4OHI A;  3VRN A;  1A08 A;  1CJ1 A;  3C7I A;  3M7F A;  1SHA A;  3NHN A;  2H46 E;  1RJA A;  3OB2 B;  1CWD L;  2AUG A;  3IN8 A;  1K9A A;  2L4K A;  1SHD A;  3PSJ A;  2LNX A;  4FBN A;  3PFV A;  3IMJ A;  1OPK A;  3VRZ A;  1XA6 A;  1Y1U A;  1LKL A;  1BKM A;  5DC9 A;  1O4E A;  2K7A B;  2DM0 A;  1LCJ A;  1P13 A;  1AYC A;  1TZE E;  3IMD A;  1O4Q A;  4OHD A;  1FU5 A;  1O4R A;  2HCK A;  1B47 A;  2RSY A;  4JEG A;  4FL2 A;  2C0O A;  4DGX A;  1O45 A;  1YVH A;  4F59 A;  1O47 A;  1ZFP E;  1BM2 A;  5GJI A;  2EYZ A;  1AYB A;  5GJH A;  3EAC A;  1BG1 A;  2CRH A;  1MW4 A;  1BKL A;  1O49 A;  1AB2 A;  1QAD A;  1LUM A;  2H5K A;  3CXL A;  4E93 A;  4NWF A;  1O4N A;  5CDW A;  2CBL A;  2EU0 A;  1NZV A;  4OHH A;  2CI8 A;  5HKY A;  1LUK A;  5I6V A;  1LUN A;  2Y1N A;  4L1B B;  3VS7 A;  5EEL A;  1KSW A;  4M4Z A;  1O4L A;  1O4F A;  1KA6 A;  1CSZ A; 
#chains in the Genus database with same CATH topology
 3UYO A;  2LQW A;  5D0J A;  3T04 A;  3CBL A;  2KGY A;  1LUI A;  2C9W A;  2Y3A B;  4GL9 E;  3OP0 A;  1NZL A;  4XZ1 A;  2LNW A;  1IJR A;  3IN7 A;  2RVF A;  5EHR A;  1BHF A;  2ABL A;  3GXW A;  1OO3 A;  4WWQ A;  1D4T A;  1KC2 A;  3MXC A;  2BBU A;  2L3T A;  2PNA A;  2JYQ A;  1AYD A;  5DC4 A;  1BMB A;  5BO4 A;  4A4B A;  2H8H A;  2MK2 A;  3PS5 A;  5IBM A;  1QG1 E;  4DGP A;  3PJP A;  1O4I A;  2KK6 A;  5HKW A;  3S9K A;  2AOA A;  2LQN A;  1I3Z A;  1R1Q A;  1A1C A;  3TL0 A;  1D1Z A;  1BHH B;  1GRI A;  2GE9 A;  4K11 A;  3N84 A;  3UF4 A;  3HCK A;  1FBZ A;  1AOU F;  2MC1 A;  1A1A A;  1M61 A;  4XZ0 A;  1O42 A;  3BUO B;  1HCS B;  1AD5 A;  1RQQ C;  1QCF A;  1JU5 A;  3QWX X;  1GHU A;  4E68 A;  2ROR A;  1X0N A;  1FBV A;  2PLD A;  1BFJ A;  4EY0 A;  1NRV A;  1BF5 A;  4K45 A;  2L6K A;  1Y57 A;  1O4B A;  3K2M A;  3PQZ A;  3EAZ A;  1BLJ A;  1O44 A;  5KAZ A;  2LCT A;  1LCK A;  1O4M A;  4TZI A;  2K79 B;  4GPL B;  5DF6 A;  2EYY A;  4FL3 A;  4JGH A;  4QSY A;  1SPS A;  2IUG A;  1BHH A;  1F1W A;  1BLK A;  2MRK A;  3VS0 A;  3N8M A;  1YVL A;  3VS1 A;  1MIL A;  1A1B A;  1O4O A;  4LUD A;  3VRY A;  2PTK A;  2YU7 A;  1O43 A;  4U17 A;  4A4C A;  2DCR A;  1A09 A;  2DX0 A;  3MAZ A;  5AUL A;  4OHL A;  2PLE A;  1IS0 A;  4OHE A;  1JYU A;  1CWE A;  3MXY A;  1CSY A;  1M27 A;  3HHM B;  2SRC A;  1A1E A;  3BUW B;  5J3X A;  3VRR A;  4H1O A;  2ETZ A;  1G83 A;  2AOB A;  4LUE A;  1SHB A;  3OB1 B;  1HCT B;  3VRO A;  2EL8 A;  1TCE A;  1H9O A;  2LRA A;  3CWG A;  4GWF A;  4P9Z A;  3TKZ A;  3BUN B;  3WA4 A;  1A81 A;  5DC0 B;  2EOB A;  2MQI A;  3VS4 A;  5AXI A;  3GQI B;  1O4G A;  3VS3 A;  1AOT F;  1LKK A;  3OVE A;  3S8L A;  1R1S A;  4EIH A;  5EEQ A;  1FMK A;  1O41 A;  3QWY A;  4P9V A;  3S8N A;  2C0T A;  2IUH A;  1O4J A;  1O4H A;  3S8O A;  2HDX A;  2CR4 A;  1X6C A;  1O4D A;  3N7Y A;  1JYQ A;  1FU6 A;  4K2R A;  2EYV A;  3LYV A;  4ROJ A;  4K44 A;  2RMX A;  1FHS A;  3BUX B;  2EKX A;  4JE4 A;  1O4C A;  3K2T A;  1JYR A;  2OZO A;  4NWG A;  2C0I A;  2HMH A;  1OPL A;  2HDV A;  1SKJ A;  2MRJ A;  3OV1 A;  2Y1M A;  1O4A A;  3VS2 A;  1O48 A;  1R1P A;  1A07 A;  3BUM B;  3VS6 A;  1BFI A;  1Z3K A;  3PSK A;  1SPR A;  3VGO A;  1PIC A;  2HUW A;  2KNO A;  1KA7 A;  4D8K A;  1FYR A;  2SHP A;  2DLZ A;  5IBS A;  3PLF B;  1OO4 A;  2FCI A;  1UUS A;  3VRP A;  2YSX A;  5EHP A;  3ZNI A;  2QMS A;  1AYA A;  2PNB A;  5HKZ A;  4X6S A;  2CS0 A;  4F5B A;  2FO0 A;  3BKB A;  2VIF A;  2IUI A;  3HIZ B;  1X27 A;  1O4P A;  2EO6 A;  2CIA A;  1JWO A;  2IZV A;  4H34 A;  1WQU A;  2ECD A;  3KFJ A;  2OQ1 A;  3GXX A;  1F2F A;  1UUR A;  4U1P A;  1D4W A;  2GSB A;  2EO3 A;  2DVJ A;  2B3O A;  3CD3 A;  2XP1 A;  3US4 A;  3VRQ A;  5EG3 B;  2CI9 A;  4F5A A;  1RPY A;  1O46 A;  3VS5 A;  2DLY A;  1O4K A;  4OHI A;  3VRN A;  1A08 A;  1CJ1 A;  3C7I A;  3M7F A;  1SHA A;  3NHN A;  2H46 E;  1RJA A;  3OB2 B;  1CWD L;  2AUG A;  3IN8 A;  1K9A A;  2L4K A;  1SHD A;  3PSJ A;  2LNX A;  4FBN A;  3PFV A;  3IMJ A;  1OPK A;  3VRZ A;  1XA6 A;  1Y1U A;  1LKL A;  1BKM A;  5DC9 A;  1O4E A;  2K7A B;  2DM0 A;  1LCJ A;  1P13 A;  1AYC A;  1TZE E;  3IMD A;  1O4Q A;  4OHD A;  1FU5 A;  1O4R A;  2HCK A;  1B47 A;  2RSY A;  4JEG A;  4FL2 A;  2C0O A;  4DGX A;  1O45 A;  1YVH A;  4F59 A;  1O47 A;  1ZFP E;  1BM2 A;  5GJI A;  2EYZ A;  1AYB A;  5GJH A;  3EAC A;  1BG1 A;  2CRH A;  1MW4 A;  1BKL A;  1O49 A;  1AB2 A;  1QAD A;  1LUM A;  2H5K A;  3CXL A;  4E93 A;  4NWF A;  1O4N A;  5CDW A;  2CBL A;  2EU0 A;  1NZV A;  4OHH A;  2CI8 A;  5HKY A;  1LUK A;  5I6V A;  1LUN A;  2Y1N A;  4L1B B;  3VS7 A;  5EEL A;  1KSW A;  4M4Z A;  1O4L A;  1O4F A;  1KA6 A;  1CSZ A; 
#chains in the Genus database with same CATH homology
 3UYO A;  2LQW A;  5D0J A;  3T04 A;  3CBL A;  1LUI A;  2C9W A;  2Y3A B;  4GL9 E;  3OP0 A;  4XZ1 A;  1NZL A;  2LNW A;  1IJR A;  3IN7 A;  2RVF A;  5EHR A;  1BHF A;  2ABL A;  3GXW A;  1OO3 A;  4WWQ A;  1D4T A;  1KC2 A;  3MXC A;  2BBU A;  2L3T A;  2PNA A;  2JYQ A;  1AYD A;  5DC4 A;  1BMB A;  5BO4 A;  4A4B A;  2H8H A;  2MK2 A;  3PS5 A;  5IBM A;  1QG1 E;  4DGP A;  3PJP A;  1O4I A;  2KK6 A;  5HKW A;  3S9K A;  2AOA A;  2LQN A;  1I3Z A;  1R1Q A;  1A1C A;  3TL0 A;  1D1Z A;  1BHH B;  1GRI A;  2GE9 A;  4K11 A;  3N84 A;  3UF4 A;  3HCK A;  1FBZ A;  1AOU F;  2MC1 A;  1A1A A;  1M61 A;  4XZ0 A;  1O42 A;  3BUO B;  1HCS B;  1AD5 A;  1RQQ C;  1QCF A;  1JU5 A;  3QWX X;  1GHU A;  4E68 A;  2ROR A;  1X0N A;  1FBV A;  2PLD A;  1BFJ A;  4EY0 A;  1NRV A;  1BF5 A;  4K45 A;  2L6K A;  1Y57 A;  1O4B A;  3K2M A;  3PQZ A;  3EAZ A;  1BLJ A;  1O44 A;  5KAZ A;  2LCT A;  1LCK A;  1O4M A;  4TZI A;  2K79 B;  4GPL B;  5DF6 A;  2EYY A;  4FL3 A;  4JGH A;  4QSY A;  1SPS A;  2IUG A;  1BHH A;  1F1W A;  1BLK A;  2MRK A;  3VS0 A;  3N8M A;  1YVL A;  3VS1 A;  1MIL A;  1A1B A;  1O4O A;  4LUD A;  3VRY A;  2PTK A;  2YU7 A;  1O43 A;  4U17 A;  4A4C A;  2DCR A;  1A09 A;  2DX0 A;  3MAZ A;  5AUL A;  4OHL A;  2PLE A;  1IS0 A;  4OHE A;  1JYU A;  1CWE A;  3MXY A;  1CSY A;  1M27 A;  3HHM B;  2SRC A;  1A1E A;  3BUW B;  5J3X A;  3VRR A;  4H1O A;  2ETZ A;  1G83 A;  2AOB A;  4LUE A;  1SHB A;  3OB1 B;  1HCT B;  3VRO A;  2EL8 A;  1TCE A;  1H9O A;  3CWG A;  4GWF A;  4P9Z A;  3TKZ A;  3BUN B;  3WA4 A;  1A81 A;  5DC0 B;  2EOB A;  2MQI A;  3VS4 A;  5AXI A;  3GQI B;  1O4G A;  3VS3 A;  1AOT F;  1LKK A;  3OVE A;  3S8L A;  1R1S A;  4EIH A;  5EEQ A;  1FMK A;  1O41 A;  3QWY A;  4P9V A;  3S8N A;  2C0T A;  2IUH A;  1O4J A;  1O4H A;  3S8O A;  2HDX A;  2CR4 A;  1X6C A;  1O4D A;  3N7Y A;  1JYQ A;  1FU6 A;  4K2R A;  2EYV A;  4ROJ A;  4K44 A;  2RMX A;  1FHS A;  3BUX B;  2EKX A;  4JE4 A;  1O4C A;  1JYR A;  2OZO A;  4NWG A;  2C0I A;  2HMH A;  1OPL A;  2HDV A;  1SKJ A;  2MRJ A;  3OV1 A;  2Y1M A;  1O4A A;  3VS2 A;  1O48 A;  1R1P A;  1A07 A;  3BUM B;  3VS6 A;  1BFI A;  1Z3K A;  3PSK A;  1SPR A;  3VGO A;  1PIC A;  2HUW A;  2KNO A;  1KA7 A;  4D8K A;  1FYR A;  2SHP A;  2DLZ A;  5IBS A;  3PLF B;  1OO4 A;  2FCI A;  1UUS A;  3VRP A;  2YSX A;  5EHP A;  3ZNI A;  2QMS A;  1AYA A;  2PNB A;  5HKZ A;  4X6S A;  2CS0 A;  4F5B A;  2FO0 A;  3BKB A;  2VIF A;  2IUI A;  3HIZ B;  1X27 A;  1O4P A;  2EO6 A;  2CIA A;  1JWO A;  2IZV A;  4H34 A;  1WQU A;  2ECD A;  3KFJ A;  2OQ1 A;  3GXX A;  1F2F A;  1UUR A;  4U1P A;  1D4W A;  2GSB A;  2EO3 A;  2DVJ A;  2B3O A;  3CD3 A;  2XP1 A;  3US4 A;  3VRQ A;  5EG3 B;  2CI9 A;  4F5A A;  1RPY A;  1O46 A;  3VS5 A;  2DLY A;  1O4K A;  4OHI A;  3VRN A;  1A08 A;  1CJ1 A;  3C7I A;  3M7F A;  1SHA A;  3NHN A;  2H46 E;  1RJA A;  3OB2 B;  1CWD L;  2AUG A;  3IN8 A;  1K9A A;  2L4K A;  1SHD A;  3PSJ A;  2LNX A;  4FBN A;  3PFV A;  3IMJ A;  1OPK A;  3VRZ A;  1XA6 A;  1Y1U A;  1LKL A;  1BKM A;  5DC9 A;  1O4E A;  2K7A B;  2DM0 A;  1LCJ A;  1P13 A;  1AYC A;  1TZE E;  3IMD A;  1O4Q A;  4OHD A;  1FU5 A;  1O4R A;  2HCK A;  1B47 A;  2RSY A;  4JEG A;  4FL2 A;  2C0O A;  4DGX A;  1O45 A;  1YVH A;  4F59 A;  1O47 A;  1ZFP E;  1BM2 A;  5GJI A;  2EYZ A;  1AYB A;  5GJH A;  3EAC A;  1BG1 A;  2CRH A;  1MW4 A;  1BKL A;  1O49 A;  1AB2 A;  1QAD A;  1LUM A;  2H5K A;  3CXL A;  4E93 A;  4NWF A;  1O4N A;  5CDW A;  2CBL A;  2EU0 A;  1NZV A;  4OHH A;  2CI8 A;  5HKY A;  1LUK A;  5I6V A;  1LUN A;  2Y1N A;  4L1B B;  3VS7 A;  5EEL A;  1KSW A;  4M4Z A;  1O4L A;  1O4F A;  1KA6 A;  1CSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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