3MXYA

Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications.
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
101
structure length
101
Chain Sequence
GSHMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 22
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2010-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3mxyA00
1LUMA 2H8HA 1O4FA 2DCRA 5EG3B 1QCFA 5EELA 2HDVA 3CD3A 5HKWA 4FL3A 1O42A 1BFJA 3BKBA 5EEQA 3BUMB 2OZOA 3T04A 2EYYA 1CWEA 3S8LA 3NHNA 1G83A 1R1SA 5I6VA 1Y1UA 1OPKA 2DLYA 1LUIA 1BHFA 2RMXA 1BMBA 1A81A 2MRKA 5BO4A 2C0OA 3S8OA 1BHHB 3CBLA 1XA6A 2CS0A 2RVFA 5CDWA 1O4OA 2PNAA 1O4BA 2IZVA 2Y1NA 1SHBA 2IUHA 4P9ZA 2JYQA 1A1EA 3BUWB 5DF6A 1LKLA 4EIHA 2HDXA 1LUNA 2RSYA 2CI9A 2EYZA 1O4PA 2SRCA 3VRRA 3VRQA 1FU5A 2EL8A 1PICA 3EAZA 1SPRA 2YSXA 5GJHA 3BUOB 2L3TA 1JWOA 1QG1E 1O45A 4H1OA 3VS0A 1AB2A 4F5AA 1CJ1A 3PFVA 1O4GA 1BG1A 2PLDA 3OB1B 5AXIA 1MILA 4A4BA 3HHMB 2GE9A 3OVEA 5KAZA 1CWDL 2LQWA 3VS1A 1M27A 3UF4A 3QWYA 3OV1A 4OHEA 4X6SA 3VRNA 1OPLA 4DGPA 2EYVA 1FU6A 1NRVA 1O4MA 4NWFA 3S8NA 1F2FA 3VGOA 4OHHA 4H34A 4QSYA 1AD5A 1O44A 4K44A 1A1CA 1AOTF 1O4RA 2EO3A 2EOBA 1A1BA 1FHSA 1UURA 4L1BB 1A1AA 4LUDA 2DLZA 3GQIB 1FYRA 1IJRA 2Y3AB 3M7FA 3ZNIA 2KNOA 1QADA 3VS2A 2EO6A 4EY0A 1O4JA 1BF5A 3MXYA 3UYOA 4WWQA 1SKJA 4JE4A 1X0NA 1CSYA 1O48A 1Z3KA 1KA6A 1K9AA 1SHDA 2OQ1A 5D0JA 1O41A 1NZLA 1CSZA 3QWXX 4JEGA 2PTKA 3CXLA 2MC1A 1BLJA 1RQQC 3K2MA 3C7IA 2LQNA 1AOUF 1AYCA 1OO3A 1O4IA 1D4TA 4GL9E 1UUSA 2L6KA 2C0IA 2CBLA 4P9VA 2GSBA 4D8KA 1HCTB 1BM2A 2L4KA 2DM0A 4NWGA 4ROJA 1X6CA 1YVLA 1JYQA 5IBMA 1GHUA 2HCKA 4XZ1A 1FBVA 3VRZA 3BUNB 4TZIA 4OHDA 1O43A 5EHPA 1H9OA 3PSJA 1AYDA 2PLEA 1NZVA 1P13A 3MAZA 1O4DA 2AOBA 4U1PA 1KC2A 1LCJA 2CI8A 1F1WA 2MQIA 3IMDA 1FBZA 2ABLA 3VRPA 1LKKA 2K7AB 3HCKA 5EHRA 4F5BA 1FMKA 1YVHA 1O4NA 2HMHA 2DVJA 2QMSA 3TL0A 1MW4A 2FCIA 2FO0A 2H46E 2EKXA 5DC0B 3VS3A 1LCKA 3GXXA 3VS5A 3N7YA 3OB2B 3KFJA 2YU7A 2LNWA 1B47A 1O4HA 1X27A 3EACA 3PJPA 3N84A 4DGXA 4LUEA 3IN8A 5J3XA 3VS7A 4E68A 4GWFA 4K11A 3MXCA 3VS6A 2MK2A 3PLFB 1KSWA 1D4WA 1TCEA 1D1ZA 1JU5A 4F59A 4M4ZA 1KA7A 1TZEE 1OO4A 3OP0A 4FL2A 1Y57A 2LCTA 2RORA 2XP1A 3S9KA 3IN7A 1WQUA 3VROA 3TKZA 2KK6A 1O4EA 5HKYA 3BUXB 1O4CA 1JYRA 1A07A 4OHIA 1SPSA 2CRHA 1BLKA 3PQZA 1HCSB 1O4LA 2AOAA 5GJIA 2K79B 3N8MA 1O49A 2EU0A 2AUGA 1GRIA 2IUGA 4A4CA 3CWGA 1O46A 1O4AA 2Y1MA 2PNBA 5AULA 1RJAA 1BKLA 3US4A 4FBNA 2HUWA 1LUKA 1I3ZA 4GPLB 2BBUA 3IMJA 1AYAA 1AYBA 3PS5A 1IS0A 4JGHA 2ECDA 2IUIA 2C9WA 1O4KA 3VS4A 3GXWA 5IBSA 2VIFA 1ZFPE 2B3OA 2C0TA 1M61A 3PSKA 2H5KA 1A08A 3HIZB 1O47A 4OHLA 1R1QA 1JYUA 2CR4A 4K45A 3WA4A 2DX0A 2SHPA 2MRJA 2ETZA 4K2RA 1BFIA 4U17A 1O4QA 3VRYA 1R1PA 1BKMA 1SHAA 5DC9A 1BHHA 5DC4A 4XZ0A 2CIAA 1RPYA 2LNXA 1A09A 4E93A 5HKZA
chains in the Genus database with same CATH superfamily
1LUMA 2H8HA 1O4FA 2DCRA 5EG3B 1QCFA 5EELA 2HDVA 3CD3A 5HKWA 4FL3A 1O42A 1BFJA 3BKBA 5EEQA 3BUMB 2OZOA 3T04A 2EYYA 2LRAA 1CWEA 3S8LA 3NHNA 1G83A 1R1SA 5I6VA 1Y1UA 1OPKA 2DLYA 1LUIA 1BHFA 2RMXA 1BMBA 1A81A 2MRKA 5BO4A 2C0OA 3S8OA 1BHHB 3CBLA 1XA6A 2CS0A 2RVFA 5CDWA 1O4OA 2PNAA 1O4BA 2IZVA 2Y1NA 1SHBA 2IUHA 4P9ZA 2JYQA 1A1EA 3BUWB 5DF6A 1LKLA 4EIHA 2HDXA 1LUNA 2RSYA 2CI9A 2EYZA 1O4PA 2SRCA 3VRRA 3VRQA 1FU5A 2EL8A 1PICA 3EAZA 1SPRA 2YSXA 5GJHA 3BUOB 2L3TA 1JWOA 1QG1E 1O45A 4H1OA 3VS0A 1AB2A 4F5AA 1CJ1A 3PFVA 1O4GA 1BG1A 2PLDA 3OB1B 5AXIA 1MILA 4A4BA 3HHMB 2GE9A 3OVEA 5KAZA 1CWDL 2LQWA 3VS1A 1M27A 3UF4A 3QWYA 3OV1A 4OHEA 4X6SA 3VRNA 1OPLA 4DGPA 2EYVA 1FU6A 1NRVA 1O4MA 4NWFA 3S8NA 1F2FA 3VGOA 4OHHA 4H34A 4QSYA 1AD5A 1O44A 4K44A 1A1CA 1AOTF 1O4RA 2EO3A 2EOBA 1A1BA 1FHSA 1UURA 4L1BB 1A1AA 4LUDA 2DLZA 3GQIB 1FYRA 1IJRA 2Y3AB 2KGYA 3M7FA 3ZNIA 2KNOA 1QADA 3VS2A 2EO6A 4EY0A 1O4JA 1BF5A 3MXYA 3UYOA 4WWQA 1SKJA 4JE4A 1X0NA 1CSYA 1O48A 1Z3KA 1KA6A 1K9AA 1SHDA 2OQ1A 5D0JA 1O41A 1NZLA 1CSZA 3QWXX 4JEGA 2PTKA 3CXLA 3K2TA 2MC1A 1BLJA 1RQQC 3K2MA 3C7IA 2LQNA 1AOUF 1AYCA 1OO3A 1O4IA 1D4TA 4GL9E 1UUSA 2L6KA 2C0IA 2CBLA 4P9VA 2GSBA 4D8KA 1HCTB 1BM2A 2L4KA 2DM0A 4NWGA 4ROJA 1X6CA 1YVLA 1JYQA 5IBMA 1GHUA 2HCKA 4XZ1A 1FBVA 3VRZA 3BUNB 4TZIA 4OHDA 1O43A 5EHPA 1H9OA 3PSJA 1AYDA 2PLEA 1NZVA 1P13A 3MAZA 1O4DA 2AOBA 4U1PA 1KC2A 1LCJA 2CI8A 1F1WA 2MQIA 3IMDA 1FBZA 2ABLA 3VRPA 1LKKA 2K7AB 3HCKA 5EHRA 4F5BA 1FMKA 1YVHA 1O4NA 2HMHA 2DVJA 2QMSA 3TL0A 1MW4A 2FCIA 2FO0A 2H46E 2EKXA 5DC0B 3VS3A 1LCKA 3GXXA 3VS5A 3N7YA 3OB2B 3KFJA 2YU7A 2LNWA 1B47A 1O4HA 1X27A 3EACA 3PJPA 3N84A 4DGXA 4LUEA 3IN8A 5J3XA 3VS7A 4E68A 4GWFA 4K11A 3MXCA 3VS6A 2MK2A 3PLFB 1KSWA 1D4WA 1TCEA 1D1ZA 1JU5A 4F59A 4M4ZA 1KA7A 1TZEE 1OO4A 3OP0A 4FL2A 1Y57A 2LCTA 2RORA 2XP1A 3S9KA 3IN7A 1WQUA 3VROA 3TKZA 2KK6A 1O4EA 5HKYA 3BUXB 1O4CA 1JYRA 1A07A 4OHIA 1SPSA 2CRHA 1BLKA 3LYVA 3PQZA 1HCSB 1O4LA 2AOAA 5GJIA 2K79B 3N8MA 1O49A 2EU0A 2AUGA 1GRIA 2IUGA 4A4CA 3CWGA 1O46A 1O4AA 2Y1MA 2PNBA 5AULA 1RJAA 1BKLA 3US4A 4FBNA 2HUWA 1LUKA 1I3ZA 4GPLB 2BBUA 3IMJA 1AYAA 1AYBA 3PS5A 1IS0A 4JGHA 2ECDA 2IUIA 2C9WA 1O4KA 3VS4A 3GXWA 5IBSA 2VIFA 1ZFPE 2B3OA 2C0TA 1M61A 3PSKA 2H5KA 1A08A 3HIZB 1O47A 4OHLA 1R1QA 1JYUA 2CR4A 4K45A 3WA4A 2DX0A 2SHPA 2MRJA 2ETZA 4K2RA 1BFIA 4U17A 1O4QA 3VRYA 1R1PA 1BKMA 1SHAA 5DC9A 1BHHA 5DC4A 4XZ0A 2CIAA 1RPYA 2LNXA 1A09A 4E93A 5HKZA
chains in the Genus database with same CATH topology
1LUMA 2H8HA 1O4FA 2DCRA 5EG3B 1QCFA 5EELA 2HDVA 3CD3A 5HKWA 4FL3A 1O42A 1BFJA 3BKBA 5EEQA 3BUMB 2OZOA 3T04A 2EYYA 1CWEA 3S8LA 3NHNA 1G83A 1R1SA 5I6VA 1Y1UA 1OPKA 2DLYA 1LUIA 1BHFA 2RMXA 1BMBA 1A81A 2MRKA 5BO4A 2C0OA 3S8OA 1BHHB 3CBLA 1XA6A 2CS0A 2RVFA 5CDWA 1O4OA 2PNAA 1O4BA 2IZVA 2Y1NA 1SHBA 2IUHA 4P9ZA 2JYQA 1A1EA 3BUWB 5DF6A 1LKLA 4EIHA 2HDXA 1LUNA 2RSYA 2CI9A 2EYZA 1O4PA 2SRCA 3VRRA 3VRQA 1FU5A 2EL8A 1PICA 3EAZA 1SPRA 2YSXA 5GJHA 3BUOB 2L3TA 1JWOA 1QG1E 1O45A 4H1OA 3VS0A 1AB2A 4F5AA 1CJ1A 3PFVA 1O4GA 1BG1A 2PLDA 3OB1B 5AXIA 1MILA 4A4BA 3HHMB 2GE9A 3OVEA 5KAZA 1CWDL 2LQWA 3VS1A 1M27A 3UF4A 3QWYA 3OV1A 4OHEA 4X6SA 3VRNA 1OPLA 4DGPA 2EYVA 1FU6A 1NRVA 1O4MA 4NWFA 3S8NA 1F2FA 3VGOA 4OHHA 4H34A 4QSYA 1AD5A 1O44A 4K44A 1A1CA 1AOTF 1O4RA 2EO3A 2EOBA 1A1BA 1FHSA 1UURA 4L1BB 1A1AA 4LUDA 2DLZA 3GQIB 1FYRA 1IJRA 2Y3AB 3M7FA 3ZNIA 2KNOA 1QADA 3VS2A 2EO6A 4EY0A 1O4JA 1BF5A 3MXYA 3UYOA 4WWQA 1SKJA 4JE4A 1X0NA 1CSYA 1O48A 1Z3KA 1KA6A 1K9AA 1SHDA 2OQ1A 5D0JA 1O41A 1NZLA 1CSZA 3QWXX 4JEGA 2PTKA 3CXLA 2MC1A 1BLJA 1RQQC 3K2MA 3C7IA 2LQNA 1AOUF 1AYCA 1OO3A 1O4IA 1D4TA 4GL9E 1UUSA 2L6KA 2C0IA 2CBLA 4P9VA 2GSBA 4D8KA 1HCTB 1BM2A 2L4KA 2DM0A 4NWGA 4ROJA 1X6CA 1YVLA 1JYQA 5IBMA 1GHUA 2HCKA 4XZ1A 1FBVA 3VRZA 3BUNB 4TZIA 4OHDA 1O43A 5EHPA 1H9OA 3PSJA 1AYDA 2PLEA 1NZVA 1P13A 3MAZA 1O4DA 2AOBA 4U1PA 1KC2A 1LCJA 2CI8A 1F1WA 2MQIA 3IMDA 1FBZA 2ABLA 3VRPA 1LKKA 2K7AB 3HCKA 5EHRA 4F5BA 1FMKA 1YVHA 1O4NA 2HMHA 2DVJA 2QMSA 3TL0A 1MW4A 2FCIA 2FO0A 2H46E 2EKXA 5DC0B 3VS3A 1LCKA 3GXXA 3VS5A 3N7YA 3OB2B 3KFJA 2YU7A 2LNWA 1B47A 1O4HA 1X27A 3EACA 3PJPA 3N84A 4DGXA 4LUEA 3IN8A 5J3XA 3VS7A 4E68A 4GWFA 4K11A 3MXCA 3VS6A 2MK2A 3PLFB 1KSWA 1D4WA 1TCEA 1D1ZA 1JU5A 4F59A 4M4ZA 1KA7A 1TZEE 1OO4A 3OP0A 4FL2A 1Y57A 2LCTA 2RORA 2XP1A 3S9KA 3IN7A 1WQUA 3VROA 3TKZA 2KK6A 1O4EA 5HKYA 3BUXB 1O4CA 1JYRA 1A07A 4OHIA 1SPSA 2CRHA 1BLKA 3PQZA 1HCSB 1O4LA 2AOAA 5GJIA 2K79B 3N8MA 1O49A 2EU0A 2AUGA 1GRIA 2IUGA 4A4CA 3CWGA 1O46A 1O4AA 2Y1MA 2PNBA 5AULA 1RJAA 1BKLA 3US4A 4FBNA 2HUWA 1LUKA 1I3ZA 4GPLB 2BBUA 3IMJA 1AYAA 1AYBA 3PS5A 1IS0A 4JGHA 2ECDA 2IUIA 2C9WA 1O4KA 3VS4A 3GXWA 5IBSA 2VIFA 1ZFPE 2B3OA 2C0TA 1M61A 3PSKA 2H5KA 1A08A 3HIZB 1O47A 4OHLA 1R1QA 1JYUA 2CR4A 4K45A 3WA4A 2DX0A 2SHPA 2MRJA 2ETZA 4K2RA 1BFIA 4U17A 1O4QA 3VRYA 1R1PA 1BKMA 1SHAA 5DC9A 1BHHA 5DC4A 4XZ0A 2CIAA 1RPYA 2LNXA 1A09A 4E93A 5HKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LUM A;  2H8H A;  1O4F A;  2DCR A;  5EG3 B;  1QCF A;  5EEL A;  2HDV A;  3CD3 A;  5HKW A;  4FL3 A;  1O42 A;  1BFJ A;  3BKB A;  5EEQ A;  3BUM B;  2OZO A;  3T04 A;  2EYY A;  1CWE A;  3S8L A;  3NHN A;  1G83 A;  1R1S A;  5I6V A;  1Y1U A;  1OPK A;  2DLY A;  1LUI A;  1BHF A;  2RMX A;  1BMB A;  1A81 A;  2MRK A;  5BO4 A;  2C0O A;  3S8O A;  1BHH B;  3CBL A;  1XA6 A;  2CS0 A;  2RVF A;  5CDW A;  1O4O A;  2PNA A;  1O4B A;  2IZV A;  2Y1N A;  1SHB A;  2IUH A;  4P9Z A;  2JYQ A;  1A1E A;  3BUW B;  5DF6 A;  1LKL A;  4EIH A;  2HDX A;  1LUN A;  2RSY A;  2CI9 A;  2EYZ A;  1O4P A;  2SRC A;  3VRR A;  3VRQ A;  1FU5 A;  2EL8 A;  1PIC A;  3EAZ A;  1SPR A;  2YSX A;  5GJH A;  3BUO B;  2L3T A;  1JWO A;  1QG1 E;  1O45 A;  4H1O A;  3VS0 A;  1AB2 A;  4F5A A;  1CJ1 A;  3PFV A;  1O4G A;  1BG1 A;  2PLD A;  3OB1 B;  5AXI A;  1MIL A;  4A4B A;  3HHM B;  2GE9 A;  3OVE A;  5KAZ A;  1CWD L;  2LQW A;  3VS1 A;  1M27 A;  3UF4 A;  3QWY A;  3OV1 A;  4OHE A;  4X6S A;  3VRN A;  1OPL A;  4DGP A;  2EYV A;  1FU6 A;  1NRV A;  1O4M A;  4NWF A;  3S8N A;  1F2F A;  3VGO A;  4OHH A;  4H34 A;  4QSY A;  1AD5 A;  1O44 A;  4K44 A;  1A1C A;  1AOT F;  1O4R A;  2EO3 A;  2EOB A;  1A1B A;  1FHS A;  1UUR A;  4L1B B;  1A1A A;  4LUD A;  2DLZ A;  3GQI B;  1FYR A;  1IJR A;  2Y3A B;  3M7F A;  3ZNI A;  2KNO A;  1QAD A;  3VS2 A;  2EO6 A;  4EY0 A;  1O4J A;  1BF5 A;  3MXY A;  3UYO A;  4WWQ A;  1SKJ A;  4JE4 A;  1X0N A;  1CSY A;  1O48 A;  1Z3K A;  1KA6 A;  1K9A A;  1SHD A;  2OQ1 A;  5D0J A;  1O41 A;  1NZL A;  1CSZ A;  3QWX X;  4JEG A;  2PTK A;  3CXL A;  2MC1 A;  1BLJ A;  1RQQ C;  3K2M A;  3C7I A;  2LQN A;  1AOU F;  1AYC A;  1OO3 A;  1O4I A;  1D4T A;  4GL9 E;  1UUS A;  2L6K A;  2C0I A;  2CBL A;  4P9V A;  2GSB A;  4D8K A;  1HCT B;  1BM2 A;  2L4K A;  2DM0 A;  4NWG A;  4ROJ A;  1X6C A;  1YVL A;  1JYQ A;  5IBM A;  1GHU A;  2HCK A;  4XZ1 A;  1FBV A;  3VRZ A;  3BUN B;  4TZI A;  4OHD A;  1O43 A;  5EHP A;  1H9O A;  3PSJ A;  1AYD A;  2PLE A;  1NZV A;  1P13 A;  3MAZ A;  1O4D A;  2AOB A;  4U1P A;  1KC2 A;  1LCJ A;  2CI8 A;  1F1W A;  2MQI A;  3IMD A;  1FBZ A;  2ABL A;  3VRP A;  1LKK A;  2K7A B;  3HCK A;  5EHR A;  4F5B A;  1FMK A;  1YVH A;  1O4N A;  2HMH A;  2DVJ A;  2QMS A;  3TL0 A;  1MW4 A;  2FCI A;  2FO0 A;  2H46 E;  2EKX A;  5DC0 B;  3VS3 A;  1LCK A;  3GXX A;  3VS5 A;  3N7Y A;  3OB2 B;  3KFJ A;  2YU7 A;  2LNW A;  1B47 A;  1O4H A;  1X27 A;  3EAC A;  3PJP A;  3N84 A;  4DGX A;  4LUE A;  3IN8 A;  5J3X A;  3VS7 A;  4E68 A;  4GWF A;  4K11 A;  3MXC A;  3VS6 A;  2MK2 A;  3PLF B;  1KSW A;  1D4W A;  1TCE A;  1D1Z A;  1JU5 A;  4F59 A;  4M4Z A;  1KA7 A;  1TZE E;  1OO4 A;  3OP0 A;  4FL2 A;  1Y57 A;  2LCT A;  2ROR A;  2XP1 A;  3S9K A;  3IN7 A;  1WQU A;  3VRO A;  3TKZ A;  2KK6 A;  1O4E A;  5HKY A;  3BUX B;  1O4C A;  1JYR A;  1A07 A;  4OHI A;  1SPS A;  2CRH A;  1BLK A;  3PQZ A;  1HCS B;  1O4L A;  2AOA A;  5GJI A;  2K79 B;  3N8M A;  1O49 A;  2EU0 A;  2AUG A;  1GRI A;  2IUG A;  4A4C A;  3CWG A;  1O46 A;  1O4A A;  2Y1M A;  2PNB A;  5AUL A;  1RJA A;  1BKL A;  3US4 A;  4FBN A;  2HUW A;  1LUK A;  1I3Z A;  4GPL B;  2BBU A;  3IMJ A;  1AYA A;  1AYB A;  3PS5 A;  1IS0 A;  4JGH A;  2ECD A;  2IUI A;  2C9W A;  1O4K A;  3VS4 A;  3GXW A;  5IBS A;  2VIF A;  1ZFP E;  2B3O A;  2C0T A;  1M61 A;  3PSK A;  2H5K A;  1A08 A;  3HIZ B;  1O47 A;  4OHL A;  1R1Q A;  1JYU A;  2CR4 A;  4K45 A;  3WA4 A;  2DX0 A;  2SHP A;  2MRJ A;  2ETZ A;  4K2R A;  1BFI A;  4U17 A;  1O4Q A;  3VRY A;  1R1P A;  1BKM A;  1SHA A;  5DC9 A;  1BHH A;  5DC4 A;  4XZ0 A;  2CIA A;  1RPY A;  2LNX A;  1A09 A;  4E93 A;  5HKZ A; 
#chains in the Genus database with same CATH topology
 1LUM A;  2H8H A;  1O4F A;  2DCR A;  5EG3 B;  1QCF A;  5EEL A;  2HDV A;  3CD3 A;  5HKW A;  4FL3 A;  1O42 A;  1BFJ A;  3BKB A;  5EEQ A;  3BUM B;  2OZO A;  3T04 A;  2EYY A;  2LRA A;  1CWE A;  3S8L A;  3NHN A;  1G83 A;  1R1S A;  5I6V A;  1Y1U A;  1OPK A;  2DLY A;  1LUI A;  1BHF A;  2RMX A;  1BMB A;  1A81 A;  2MRK A;  5BO4 A;  2C0O A;  3S8O A;  1BHH B;  3CBL A;  1XA6 A;  2CS0 A;  2RVF A;  5CDW A;  1O4O A;  2PNA A;  1O4B A;  2IZV A;  2Y1N A;  1SHB A;  2IUH A;  4P9Z A;  2JYQ A;  1A1E A;  3BUW B;  5DF6 A;  1LKL A;  4EIH A;  2HDX A;  1LUN A;  2RSY A;  2CI9 A;  2EYZ A;  1O4P A;  2SRC A;  3VRR A;  3VRQ A;  1FU5 A;  2EL8 A;  1PIC A;  3EAZ A;  1SPR A;  2YSX A;  5GJH A;  3BUO B;  2L3T A;  1JWO A;  1QG1 E;  1O45 A;  4H1O A;  3VS0 A;  1AB2 A;  4F5A A;  1CJ1 A;  3PFV A;  1O4G A;  1BG1 A;  2PLD A;  3OB1 B;  5AXI A;  1MIL A;  4A4B A;  3HHM B;  2GE9 A;  3OVE A;  5KAZ A;  1CWD L;  2LQW A;  3VS1 A;  1M27 A;  3UF4 A;  3QWY A;  3OV1 A;  4OHE A;  4X6S A;  3VRN A;  1OPL A;  4DGP A;  2EYV A;  1FU6 A;  1NRV A;  1O4M A;  4NWF A;  3S8N A;  1F2F A;  3VGO A;  4OHH A;  4H34 A;  4QSY A;  1AD5 A;  1O44 A;  4K44 A;  1A1C A;  1AOT F;  1O4R A;  2EO3 A;  2EOB A;  1A1B A;  1FHS A;  1UUR A;  4L1B B;  1A1A A;  4LUD A;  2DLZ A;  3GQI B;  1FYR A;  1IJR A;  2Y3A B;  2KGY A;  3M7F A;  3ZNI A;  2KNO A;  1QAD A;  3VS2 A;  2EO6 A;  4EY0 A;  1O4J A;  1BF5 A;  3MXY A;  3UYO A;  4WWQ A;  1SKJ A;  4JE4 A;  1X0N A;  1CSY A;  1O48 A;  1Z3K A;  1KA6 A;  1K9A A;  1SHD A;  2OQ1 A;  5D0J A;  1O41 A;  1NZL A;  1CSZ A;  3QWX X;  4JEG A;  2PTK A;  3CXL A;  3K2T A;  2MC1 A;  1BLJ A;  1RQQ C;  3K2M A;  3C7I A;  2LQN A;  1AOU F;  1AYC A;  1OO3 A;  1O4I A;  1D4T A;  4GL9 E;  1UUS A;  2L6K A;  2C0I A;  2CBL A;  4P9V A;  2GSB A;  4D8K A;  1HCT B;  1BM2 A;  2L4K A;  2DM0 A;  4NWG A;  4ROJ A;  1X6C A;  1YVL A;  1JYQ A;  5IBM A;  1GHU A;  2HCK A;  4XZ1 A;  1FBV A;  3VRZ A;  3BUN B;  4TZI A;  4OHD A;  1O43 A;  5EHP A;  1H9O A;  3PSJ A;  1AYD A;  2PLE A;  1NZV A;  1P13 A;  3MAZ A;  1O4D A;  2AOB A;  4U1P A;  1KC2 A;  1LCJ A;  2CI8 A;  1F1W A;  2MQI A;  3IMD A;  1FBZ A;  2ABL A;  3VRP A;  1LKK A;  2K7A B;  3HCK A;  5EHR A;  4F5B A;  1FMK A;  1YVH A;  1O4N A;  2HMH A;  2DVJ A;  2QMS A;  3TL0 A;  1MW4 A;  2FCI A;  2FO0 A;  2H46 E;  2EKX A;  5DC0 B;  3VS3 A;  1LCK A;  3GXX A;  3VS5 A;  3N7Y A;  3OB2 B;  3KFJ A;  2YU7 A;  2LNW A;  1B47 A;  1O4H A;  1X27 A;  3EAC A;  3PJP A;  3N84 A;  4DGX A;  4LUE A;  3IN8 A;  5J3X A;  3VS7 A;  4E68 A;  4GWF A;  4K11 A;  3MXC A;  3VS6 A;  2MK2 A;  3PLF B;  1KSW A;  1D4W A;  1TCE A;  1D1Z A;  1JU5 A;  4F59 A;  4M4Z A;  1KA7 A;  1TZE E;  1OO4 A;  3OP0 A;  4FL2 A;  1Y57 A;  2LCT A;  2ROR A;  2XP1 A;  3S9K A;  3IN7 A;  1WQU A;  3VRO A;  3TKZ A;  2KK6 A;  1O4E A;  5HKY A;  3BUX B;  1O4C A;  1JYR A;  1A07 A;  4OHI A;  1SPS A;  2CRH A;  1BLK A;  3LYV A;  3PQZ A;  1HCS B;  1O4L A;  2AOA A;  5GJI A;  2K79 B;  3N8M A;  1O49 A;  2EU0 A;  2AUG A;  1GRI A;  2IUG A;  4A4C A;  3CWG A;  1O46 A;  1O4A A;  2Y1M A;  2PNB A;  5AUL A;  1RJA A;  1BKL A;  3US4 A;  4FBN A;  2HUW A;  1LUK A;  1I3Z A;  4GPL B;  2BBU A;  3IMJ A;  1AYA A;  1AYB A;  3PS5 A;  1IS0 A;  4JGH A;  2ECD A;  2IUI A;  2C9W A;  1O4K A;  3VS4 A;  3GXW A;  5IBS A;  2VIF A;  1ZFP E;  2B3O A;  2C0T A;  1M61 A;  3PSK A;  2H5K A;  1A08 A;  3HIZ B;  1O47 A;  4OHL A;  1R1Q A;  1JYU A;  2CR4 A;  4K45 A;  3WA4 A;  2DX0 A;  2SHP A;  2MRJ A;  2ETZ A;  4K2R A;  1BFI A;  4U17 A;  1O4Q A;  3VRY A;  1R1P A;  1BKM A;  1SHA A;  5DC9 A;  1BHH A;  5DC4 A;  4XZ0 A;  2CIA A;  1RPY A;  2LNX A;  1A09 A;  4E93 A;  5HKZ A; 
#chains in the Genus database with same CATH homology
 1LUM A;  2H8H A;  1O4F A;  2DCR A;  5EG3 B;  1QCF A;  5EEL A;  2HDV A;  3CD3 A;  5HKW A;  4FL3 A;  1O42 A;  1BFJ A;  3BKB A;  5EEQ A;  3BUM B;  2OZO A;  3T04 A;  2EYY A;  1CWE A;  3S8L A;  3NHN A;  1G83 A;  1R1S A;  5I6V A;  1Y1U A;  1OPK A;  2DLY A;  1LUI A;  1BHF A;  2RMX A;  1BMB A;  1A81 A;  2MRK A;  5BO4 A;  2C0O A;  3S8O A;  1BHH B;  3CBL A;  1XA6 A;  2CS0 A;  2RVF A;  5CDW A;  1O4O A;  2PNA A;  1O4B A;  2IZV A;  2Y1N A;  1SHB A;  2IUH A;  4P9Z A;  2JYQ A;  1A1E A;  3BUW B;  5DF6 A;  1LKL A;  4EIH A;  2HDX A;  1LUN A;  2RSY A;  2CI9 A;  2EYZ A;  1O4P A;  2SRC A;  3VRR A;  3VRQ A;  1FU5 A;  2EL8 A;  1PIC A;  3EAZ A;  1SPR A;  2YSX A;  5GJH A;  3BUO B;  2L3T A;  1JWO A;  1QG1 E;  1O45 A;  4H1O A;  3VS0 A;  1AB2 A;  4F5A A;  1CJ1 A;  3PFV A;  1O4G A;  1BG1 A;  2PLD A;  3OB1 B;  5AXI A;  1MIL A;  4A4B A;  3HHM B;  2GE9 A;  3OVE A;  5KAZ A;  1CWD L;  2LQW A;  3VS1 A;  1M27 A;  3UF4 A;  3QWY A;  3OV1 A;  4OHE A;  4X6S A;  3VRN A;  1OPL A;  4DGP A;  2EYV A;  1FU6 A;  1NRV A;  1O4M A;  4NWF A;  3S8N A;  1F2F A;  3VGO A;  4OHH A;  4H34 A;  4QSY A;  1AD5 A;  1O44 A;  4K44 A;  1A1C A;  1AOT F;  1O4R A;  2EO3 A;  2EOB A;  1A1B A;  1FHS A;  1UUR A;  4L1B B;  1A1A A;  4LUD A;  2DLZ A;  3GQI B;  1FYR A;  1IJR A;  2Y3A B;  3M7F A;  3ZNI A;  2KNO A;  1QAD A;  3VS2 A;  2EO6 A;  4EY0 A;  1O4J A;  1BF5 A;  3MXY A;  3UYO A;  4WWQ A;  1SKJ A;  4JE4 A;  1X0N A;  1CSY A;  1O48 A;  1Z3K A;  1KA6 A;  1K9A A;  1SHD A;  2OQ1 A;  5D0J A;  1O41 A;  1NZL A;  1CSZ A;  3QWX X;  4JEG A;  2PTK A;  3CXL A;  2MC1 A;  1BLJ A;  1RQQ C;  3K2M A;  3C7I A;  2LQN A;  1AOU F;  1AYC A;  1OO3 A;  1O4I A;  1D4T A;  4GL9 E;  1UUS A;  2L6K A;  2C0I A;  2CBL A;  4P9V A;  2GSB A;  4D8K A;  1HCT B;  1BM2 A;  2L4K A;  2DM0 A;  4NWG A;  4ROJ A;  1X6C A;  1YVL A;  1JYQ A;  5IBM A;  1GHU A;  2HCK A;  4XZ1 A;  1FBV A;  3VRZ A;  3BUN B;  4TZI A;  4OHD A;  1O43 A;  5EHP A;  1H9O A;  3PSJ A;  1AYD A;  2PLE A;  1NZV A;  1P13 A;  3MAZ A;  1O4D A;  2AOB A;  4U1P A;  1KC2 A;  1LCJ A;  2CI8 A;  1F1W A;  2MQI A;  3IMD A;  1FBZ A;  2ABL A;  3VRP A;  1LKK A;  2K7A B;  3HCK A;  5EHR A;  4F5B A;  1FMK A;  1YVH A;  1O4N A;  2HMH A;  2DVJ A;  2QMS A;  3TL0 A;  1MW4 A;  2FCI A;  2FO0 A;  2H46 E;  2EKX A;  5DC0 B;  3VS3 A;  1LCK A;  3GXX A;  3VS5 A;  3N7Y A;  3OB2 B;  3KFJ A;  2YU7 A;  2LNW A;  1B47 A;  1O4H A;  1X27 A;  3EAC A;  3PJP A;  3N84 A;  4DGX A;  4LUE A;  3IN8 A;  5J3X A;  3VS7 A;  4E68 A;  4GWF A;  4K11 A;  3MXC A;  3VS6 A;  2MK2 A;  3PLF B;  1KSW A;  1D4W A;  1TCE A;  1D1Z A;  1JU5 A;  4F59 A;  4M4Z A;  1KA7 A;  1TZE E;  1OO4 A;  3OP0 A;  4FL2 A;  1Y57 A;  2LCT A;  2ROR A;  2XP1 A;  3S9K A;  3IN7 A;  1WQU A;  3VRO A;  3TKZ A;  2KK6 A;  1O4E A;  5HKY A;  3BUX B;  1O4C A;  1JYR A;  1A07 A;  4OHI A;  1SPS A;  2CRH A;  1BLK A;  3PQZ A;  1HCS B;  1O4L A;  2AOA A;  5GJI A;  2K79 B;  3N8M A;  1O49 A;  2EU0 A;  2AUG A;  1GRI A;  2IUG A;  4A4C A;  3CWG A;  1O46 A;  1O4A A;  2Y1M A;  2PNB A;  5AUL A;  1RJA A;  1BKL A;  3US4 A;  4FBN A;  2HUW A;  1LUK A;  1I3Z A;  4GPL B;  2BBU A;  3IMJ A;  1AYA A;  1AYB A;  3PS5 A;  1IS0 A;  4JGH A;  2ECD A;  2IUI A;  2C9W A;  1O4K A;  3VS4 A;  3GXW A;  5IBS A;  2VIF A;  1ZFP E;  2B3O A;  2C0T A;  1M61 A;  3PSK A;  2H5K A;  1A08 A;  3HIZ B;  1O47 A;  4OHL A;  1R1Q A;  1JYU A;  2CR4 A;  4K45 A;  3WA4 A;  2DX0 A;  2SHP A;  2MRJ A;  2ETZ A;  4K2R A;  1BFI A;  4U17 A;  1O4Q A;  3VRY A;  1R1P A;  1BKM A;  1SHA A;  5DC9 A;  1BHH A;  5DC4 A;  4XZ0 A;  2CIA A;  1RPY A;  2LNX A;  1A09 A;  4E93 A;  5HKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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