3N8MA

Crystal structure of the grb2 sh2 domain in complex with an acyclic ligand having the sequence pyvnvp
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
99
structure length
99
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/peptide
source organism Homo sapiens
publication title Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 2
total genus 25
structure length 99
sequence length 99
ec nomenclature
pdb deposition date 2010-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3n8mA00
1O4HA 5DC0B 1O4IA 3UF4A 1BKLA 3QWYA 1IJRA 1O47A 1R1SA 4GWFA 2K7AB 2CRHA 1X0NA 4WWQA 2C9WA 1BG1A 3PLFB 1O46A 3BKBA 3TKZA 1WQUA 4D8KA 1SHAA 3GXXA 1AB2A 5DF6A 4EY0A 1BF5A 2HMHA 2SHPA 3HHMB 2QMSA 3VGOA 1LUKA 4ROJA 5AXIA 3HCKA 3PSJA 4XZ0A 1B47A 3PSKA 3S8LA 1PICA 1A81A 1K9AA 1Z3KA 3PQZA 5EELA 5EHRA 1FYRA 2LCTA 5KAZA 1NZVA 1ZFPE 4NWFA 1FU5A 1YVLA 3BUOB 1QCFA 1KA6A 3CXLA 3MXYA 4FBNA 2CS0A 1OPKA 1OO3A 1O4EA 4DGXA 1TCEA 2AOBA 4F5BA 4OHLA 1QADA 1JYRA 1QG1E 2LNXA 2OZOA 3EAZA 4JGHA 2LQWA 1FU6A 5EHPA 1D1ZA 1JU5A 3BUWB 2L4KA 2SRCA 4E93A 2LQNA 5HKZA 5I6VA 4K45A 3OP0A 3TL0A 1KA7A 1Y1UA 3VS5A 3VS2A 2FO0A 3MXCA 4XZ1A 4H1OA 1AYBA 4OHEA 2EYZA 3VS7A 4H34A 3VRQA 3OB2B 4LUDA 2YSXA 1O4NA 3IN8A 5GJHA 1AD5A 4K11A 1O4BA 2EKXA 2HCKA 5IBMA 3OB1B 1I3ZA 1NZLA 1O4JA 2GSBA 2RSYA 2DLYA 1O4CA 1GRIA 4DGPA 4U17A 3BUMB 2MC1A 1R1QA 2PLDA 3VS4A 1GHUA 3VS1A 2PLEA 1JYUA 3MAZA 4A4BA 5J3XA 1LCJA 1MILA 3VRYA 2GE9A 1O44A 3K2MA 2RVFA 1LKKA 1LKLA 1O45A 1O42A 4P9VA 1UURA 1M61A 1CJ1A 1CWDL 2PTKA 3VS6A 3PJPA 3CBLA 1LUMA 2YU7A 2H8HA 1O4AA 4P9ZA 2Y3AB 1O4LA 4X6SA 2AOAA 1Y57A 2L3TA 1A09A 1A1AA 3N8MA 1CWEA 4OHIA 3VRRA 2IUGA 1X6CA 2EOBA 2EO3A 1BLKA 5HKWA 2DM0A 2LNWA 4F5AA 5EEQA 1BHFA 2FCIA 2VIFA 1SHDA 2Y1MA 2CI8A 2Y1NA 4EIHA 1A08A 1O4GA 5HKYA 3CWGA 2OQ1A 2DVJA 1IS0A 3S8NA 3BUNB 3IMDA 3PS5A 1AYCA 2EU0A 3T04A 2ABLA 3UYOA 2PNBA 5BO4A 1M27A 1OPLA 2BBUA 3VRPA 4F59A 1H9OA 1KC2A 2EYVA 3VS3A 1AYDA 1CSZA 1O4DA 3VRZA 1FBZA 1BFIA 3S8OA 2CI9A 2CIAA 4OHHA 1O48A 2MRKA 2HDVA 2ECDA 2C0TA 3GQIB 1BHHA 1SKJA 4K44A 1O4FA 2CBLA 3VRNA 1LUIA 2EYYA 2C0IA 1TZEE 1O41A 1XA6A 1A1BA 2PNAA 4NWGA 4FL3A 1G83A 1AYAA 4GL9E 4K2RA 1A07A 4JEGA 2MRJA 3VS0A 1CSYA 2C0OA 3PFVA 4U1PA 1SPSA 1BHHB 2IZVA 1OO4A 1O4MA 3NHNA 2KNOA 4E68A 1R1PA 2HDXA 5DC9A 2XP1A 1AOTF 1O4OA 1UUSA 3IMJA 3OVEA 1LUNA 3IN7A 3CD3A 4TZIA 2DLZA 2H5KA 4M4ZA 3KFJA 5CDWA 1O4PA 2RMXA 4LUEA 1HCTB 1FBVA 3HIZB 1BLJA 1BKMA 1A1EA 3GXWA 1P13A 4A4CA 1X27A 5DC4A 2HUWA 2DX0A 1SPRA 3BUXB 3EACA 5AULA 3QWXX 3C7IA 1F1WA 1O4KA 2K79B 1NRVA 3US4A 3OV1A 3VROA 1O43A 4OHDA 1O4RA 1RPYA 1JWOA 4GPLB 3M7FA 2MK2A 2MQIA 2IUIA 2B3OA 1AOUF 2RORA 2CR4A 1SHBA 1A1CA 1D4TA 1FMKA 1YVHA 1JYQA 3WA4A 3ZNIA 1D4WA 2EL8A 2JYQA 3N84A 2IUHA 4JE4A 1O49A 2KK6A 1FHSA 1O4QA 2AUGA 1BFJA 1KSWA 2H46E 2L6KA 3S9KA 4FL2A 2EO6A 3N7YA 5D0JA 4L1BB 1LCKA 1F2FA 4QSYA 1BMBA 1MW4A 2DCRA 2ETZA 1BM2A 1RQQC 5GJIA 1RJAA 5EG3B 5IBSA 1HCSB
chains in the Genus database with same CATH superfamily
1O4HA 5DC0B 1O4IA 3UF4A 1BKLA 3QWYA 1IJRA 1O47A 1R1SA 4GWFA 2K7AB 2CRHA 1X0NA 4WWQA 2C9WA 1BG1A 3PLFB 1O46A 3BKBA 3TKZA 1WQUA 4D8KA 1SHAA 3GXXA 1AB2A 5DF6A 4EY0A 1BF5A 2HMHA 2SHPA 3HHMB 2QMSA 3VGOA 1LUKA 4ROJA 5AXIA 3HCKA 3PSJA 4XZ0A 1B47A 3PSKA 3S8LA 1PICA 1A81A 1K9AA 1Z3KA 3PQZA 5EELA 5EHRA 1FYRA 2LCTA 5KAZA 1NZVA 1ZFPE 4NWFA 1FU5A 1YVLA 3BUOB 1QCFA 1KA6A 3CXLA 3MXYA 4FBNA 2CS0A 1OPKA 1OO3A 1O4EA 4DGXA 1TCEA 2AOBA 4F5BA 4OHLA 1QADA 1JYRA 1QG1E 2LNXA 2OZOA 3EAZA 4JGHA 2LQWA 3K2TA 1FU6A 5EHPA 1D1ZA 1JU5A 3BUWB 2L4KA 2SRCA 4E93A 2LQNA 5HKZA 5I6VA 4K45A 3OP0A 3TL0A 1KA7A 1Y1UA 3VS5A 3VS2A 2FO0A 3MXCA 4XZ1A 4H1OA 1AYBA 4OHEA 2EYZA 3VS7A 4H34A 3VRQA 3OB2B 4LUDA 2YSXA 1O4NA 3IN8A 5GJHA 1AD5A 4K11A 1O4BA 2EKXA 2HCKA 5IBMA 3OB1B 1I3ZA 1NZLA 1O4JA 2GSBA 2RSYA 2DLYA 1O4CA 1GRIA 4DGPA 4U17A 3BUMB 2MC1A 1R1QA 2PLDA 3VS4A 1GHUA 3VS1A 2PLEA 1JYUA 3MAZA 4A4BA 5J3XA 1LCJA 2KGYA 1MILA 3VRYA 3LYVA 2GE9A 1O44A 3K2MA 2RVFA 1LKKA 1LKLA 1O45A 1O42A 4P9VA 1UURA 1M61A 1CJ1A 1CWDL 2PTKA 3VS6A 3PJPA 3CBLA 1LUMA 2YU7A 2H8HA 1O4AA 4P9ZA 2Y3AB 1O4LA 4X6SA 2AOAA 1Y57A 2L3TA 1A09A 1A1AA 3N8MA 1CWEA 4OHIA 3VRRA 2IUGA 1X6CA 2EOBA 2EO3A 1BLKA 5HKWA 2DM0A 2LNWA 4F5AA 5EEQA 1BHFA 2FCIA 2VIFA 1SHDA 2Y1MA 2CI8A 2Y1NA 4EIHA 1A08A 1O4GA 5HKYA 3CWGA 2OQ1A 2DVJA 1IS0A 3S8NA 3BUNB 3IMDA 3PS5A 1AYCA 2EU0A 3T04A 2ABLA 3UYOA 2PNBA 5BO4A 1M27A 1OPLA 2BBUA 3VRPA 4F59A 1H9OA 1KC2A 2EYVA 3VS3A 1AYDA 1CSZA 1O4DA 3VRZA 1FBZA 1BFIA 3S8OA 2CI9A 2CIAA 4OHHA 1O48A 2MRKA 2HDVA 2ECDA 2C0TA 3GQIB 1BHHA 1SKJA 4K44A 1O4FA 2CBLA 3VRNA 1LUIA 2EYYA 2C0IA 1TZEE 1O41A 1XA6A 1A1BA 2PNAA 4NWGA 4FL3A 1G83A 1AYAA 4GL9E 4K2RA 1A07A 4JEGA 2MRJA 3VS0A 1CSYA 2C0OA 3PFVA 4U1PA 1SPSA 1BHHB 2IZVA 1OO4A 1O4MA 3NHNA 2KNOA 4E68A 1R1PA 2HDXA 5DC9A 2XP1A 1AOTF 1O4OA 1UUSA 3IMJA 3OVEA 1LUNA 3IN7A 3CD3A 4TZIA 2DLZA 2H5KA 4M4ZA 3KFJA 5CDWA 1O4PA 2RMXA 4LUEA 1HCTB 1FBVA 3HIZB 1BLJA 1BKMA 1A1EA 3GXWA 1P13A 4A4CA 1X27A 5DC4A 2HUWA 2DX0A 1SPRA 3BUXB 3EACA 5AULA 3QWXX 3C7IA 1F1WA 1O4KA 2K79B 1NRVA 3US4A 3OV1A 3VROA 1O43A 4OHDA 1O4RA 1RPYA 1JWOA 4GPLB 3M7FA 2MK2A 2MQIA 2IUIA 2B3OA 1AOUF 2RORA 2CR4A 1SHBA 1A1CA 1D4TA 1FMKA 1YVHA 1JYQA 3WA4A 3ZNIA 1D4WA 2EL8A 2JYQA 3N84A 2IUHA 4JE4A 1O49A 2KK6A 1FHSA 1O4QA 2AUGA 1BFJA 1KSWA 2H46E 2L6KA 3S9KA 4FL2A 2EO6A 3N7YA 5D0JA 4L1BB 1LCKA 1F2FA 4QSYA 1BMBA 1MW4A 2DCRA 2ETZA 1BM2A 1RQQC 5GJIA 1RJAA 2LRAA 5EG3B 5IBSA 1HCSB
chains in the Genus database with same CATH topology
1O4HA 5DC0B 1O4IA 3UF4A 1BKLA 3QWYA 1IJRA 1O47A 1R1SA 4GWFA 2K7AB 2CRHA 1X0NA 4WWQA 2C9WA 1BG1A 3PLFB 1O46A 3BKBA 3TKZA 1WQUA 4D8KA 1SHAA 3GXXA 1AB2A 5DF6A 4EY0A 1BF5A 2HMHA 2SHPA 3HHMB 2QMSA 3VGOA 1LUKA 4ROJA 5AXIA 3HCKA 3PSJA 4XZ0A 1B47A 3PSKA 3S8LA 1PICA 1A81A 1K9AA 1Z3KA 3PQZA 5EELA 5EHRA 1FYRA 2LCTA 5KAZA 1NZVA 1ZFPE 4NWFA 1FU5A 1YVLA 3BUOB 1QCFA 1KA6A 3CXLA 3MXYA 4FBNA 2CS0A 1OPKA 1OO3A 1O4EA 4DGXA 1TCEA 2AOBA 4F5BA 4OHLA 1QADA 1JYRA 1QG1E 2LNXA 2OZOA 3EAZA 4JGHA 2LQWA 1FU6A 5EHPA 1D1ZA 1JU5A 3BUWB 2L4KA 2SRCA 4E93A 2LQNA 5HKZA 5I6VA 4K45A 3OP0A 3TL0A 1KA7A 1Y1UA 3VS5A 3VS2A 2FO0A 3MXCA 4XZ1A 4H1OA 1AYBA 4OHEA 2EYZA 3VS7A 4H34A 3VRQA 3OB2B 4LUDA 2YSXA 1O4NA 3IN8A 5GJHA 1AD5A 4K11A 1O4BA 2EKXA 2HCKA 5IBMA 3OB1B 1I3ZA 1NZLA 1O4JA 2GSBA 2RSYA 2DLYA 1O4CA 1GRIA 4DGPA 4U17A 3BUMB 2MC1A 1R1QA 2PLDA 3VS4A 1GHUA 3VS1A 2PLEA 1JYUA 3MAZA 4A4BA 5J3XA 1LCJA 1MILA 3VRYA 2GE9A 1O44A 3K2MA 2RVFA 1LKKA 1LKLA 1O45A 1O42A 4P9VA 1UURA 1M61A 1CJ1A 1CWDL 2PTKA 3VS6A 3PJPA 3CBLA 1LUMA 2YU7A 2H8HA 1O4AA 4P9ZA 2Y3AB 1O4LA 4X6SA 2AOAA 1Y57A 2L3TA 1A09A 1A1AA 3N8MA 1CWEA 4OHIA 3VRRA 2IUGA 1X6CA 2EOBA 2EO3A 1BLKA 5HKWA 2DM0A 2LNWA 4F5AA 5EEQA 1BHFA 2FCIA 2VIFA 1SHDA 2Y1MA 2CI8A 2Y1NA 4EIHA 1A08A 1O4GA 5HKYA 3CWGA 2OQ1A 2DVJA 1IS0A 3S8NA 3BUNB 3IMDA 3PS5A 1AYCA 2EU0A 3T04A 2ABLA 3UYOA 2PNBA 5BO4A 1M27A 1OPLA 2BBUA 3VRPA 4F59A 1H9OA 1KC2A 2EYVA 3VS3A 1AYDA 1CSZA 1O4DA 3VRZA 1FBZA 1BFIA 3S8OA 2CI9A 2CIAA 4OHHA 1O48A 2MRKA 2HDVA 2ECDA 2C0TA 3GQIB 1BHHA 1SKJA 4K44A 1O4FA 2CBLA 3VRNA 1LUIA 2EYYA 2C0IA 1TZEE 1O41A 1XA6A 1A1BA 2PNAA 4NWGA 4FL3A 1G83A 1AYAA 4GL9E 4K2RA 1A07A 4JEGA 2MRJA 3VS0A 1CSYA 2C0OA 3PFVA 4U1PA 1SPSA 1BHHB 2IZVA 1OO4A 1O4MA 3NHNA 2KNOA 4E68A 1R1PA 2HDXA 5DC9A 2XP1A 1AOTF 1O4OA 1UUSA 3IMJA 3OVEA 1LUNA 3IN7A 3CD3A 4TZIA 2DLZA 2H5KA 4M4ZA 3KFJA 5CDWA 1O4PA 2RMXA 4LUEA 1HCTB 1FBVA 3HIZB 1BLJA 1BKMA 1A1EA 3GXWA 1P13A 4A4CA 1X27A 5DC4A 2HUWA 2DX0A 1SPRA 3BUXB 3EACA 5AULA 3QWXX 3C7IA 1F1WA 1O4KA 2K79B 1NRVA 3US4A 3OV1A 3VROA 1O43A 4OHDA 1O4RA 1RPYA 1JWOA 4GPLB 3M7FA 2MK2A 2MQIA 2IUIA 2B3OA 1AOUF 2RORA 2CR4A 1SHBA 1A1CA 1D4TA 1FMKA 1YVHA 1JYQA 3WA4A 3ZNIA 1D4WA 2EL8A 2JYQA 3N84A 2IUHA 4JE4A 1O49A 2KK6A 1FHSA 1O4QA 2AUGA 1BFJA 1KSWA 2H46E 2L6KA 3S9KA 4FL2A 2EO6A 3N7YA 5D0JA 4L1BB 1LCKA 1F2FA 4QSYA 1BMBA 1MW4A 2DCRA 2ETZA 1BM2A 1RQQC 5GJIA 1RJAA 5EG3B 5IBSA 1HCSB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O4H A;  5DC0 B;  1O4I A;  3UF4 A;  1BKL A;  3QWY A;  1IJR A;  1O47 A;  1R1S A;  4GWF A;  2K7A B;  2CRH A;  1X0N A;  4WWQ A;  2C9W A;  1BG1 A;  3PLF B;  1O46 A;  3BKB A;  3TKZ A;  1WQU A;  4D8K A;  1SHA A;  3GXX A;  1AB2 A;  5DF6 A;  4EY0 A;  1BF5 A;  2HMH A;  2SHP A;  3HHM B;  2QMS A;  3VGO A;  1LUK A;  4ROJ A;  5AXI A;  3HCK A;  3PSJ A;  4XZ0 A;  1B47 A;  3PSK A;  3S8L A;  1PIC A;  1A81 A;  1K9A A;  1Z3K A;  3PQZ A;  5EEL A;  5EHR A;  1FYR A;  2LCT A;  5KAZ A;  1NZV A;  1ZFP E;  4NWF A;  1FU5 A;  1YVL A;  3BUO B;  1QCF A;  1KA6 A;  3CXL A;  3MXY A;  4FBN A;  2CS0 A;  1OPK A;  1OO3 A;  1O4E A;  4DGX A;  1TCE A;  2AOB A;  4F5B A;  4OHL A;  1QAD A;  1JYR A;  1QG1 E;  2LNX A;  2OZO A;  3EAZ A;  4JGH A;  2LQW A;  1FU6 A;  5EHP A;  1D1Z A;  1JU5 A;  3BUW B;  2L4K A;  2SRC A;  4E93 A;  2LQN A;  5HKZ A;  5I6V A;  4K45 A;  3OP0 A;  3TL0 A;  1KA7 A;  1Y1U A;  3VS5 A;  3VS2 A;  2FO0 A;  3MXC A;  4XZ1 A;  4H1O A;  1AYB A;  4OHE A;  2EYZ A;  3VS7 A;  4H34 A;  3VRQ A;  3OB2 B;  4LUD A;  2YSX A;  1O4N A;  3IN8 A;  5GJH A;  1AD5 A;  4K11 A;  1O4B A;  2EKX A;  2HCK A;  5IBM A;  3OB1 B;  1I3Z A;  1NZL A;  1O4J A;  2GSB A;  2RSY A;  2DLY A;  1O4C A;  1GRI A;  4DGP A;  4U17 A;  3BUM B;  2MC1 A;  1R1Q A;  2PLD A;  3VS4 A;  1GHU A;  3VS1 A;  2PLE A;  1JYU A;  3MAZ A;  4A4B A;  5J3X A;  1LCJ A;  1MIL A;  3VRY A;  2GE9 A;  1O44 A;  3K2M A;  2RVF A;  1LKK A;  1LKL A;  1O45 A;  1O42 A;  4P9V A;  1UUR A;  1M61 A;  1CJ1 A;  1CWD L;  2PTK A;  3VS6 A;  3PJP A;  3CBL A;  1LUM A;  2YU7 A;  2H8H A;  1O4A A;  4P9Z A;  2Y3A B;  1O4L A;  4X6S A;  2AOA A;  1Y57 A;  2L3T A;  1A09 A;  1A1A A;  3N8M A;  1CWE A;  4OHI A;  3VRR A;  2IUG A;  1X6C A;  2EOB A;  2EO3 A;  1BLK A;  5HKW A;  2DM0 A;  2LNW A;  4F5A A;  5EEQ A;  1BHF A;  2FCI A;  2VIF A;  1SHD A;  2Y1M A;  2CI8 A;  2Y1N A;  4EIH A;  1A08 A;  1O4G A;  5HKY A;  3CWG A;  2OQ1 A;  2DVJ A;  1IS0 A;  3S8N A;  3BUN B;  3IMD A;  3PS5 A;  1AYC A;  2EU0 A;  3T04 A;  2ABL A;  3UYO A;  2PNB A;  5BO4 A;  1M27 A;  1OPL A;  2BBU A;  3VRP A;  4F59 A;  1H9O A;  1KC2 A;  2EYV A;  3VS3 A;  1AYD A;  1CSZ A;  1O4D A;  3VRZ A;  1FBZ A;  1BFI A;  3S8O A;  2CI9 A;  2CIA A;  4OHH A;  1O48 A;  2MRK A;  2HDV A;  2ECD A;  2C0T A;  3GQI B;  1BHH A;  1SKJ A;  4K44 A;  1O4F A;  2CBL A;  3VRN A;  1LUI A;  2EYY A;  2C0I A;  1TZE E;  1O41 A;  1XA6 A;  1A1B A;  2PNA A;  4NWG A;  4FL3 A;  1G83 A;  1AYA A;  4GL9 E;  4K2R A;  1A07 A;  4JEG A;  2MRJ A;  3VS0 A;  1CSY A;  2C0O A;  3PFV A;  4U1P A;  1SPS A;  1BHH B;  2IZV A;  1OO4 A;  1O4M A;  3NHN A;  2KNO A;  4E68 A;  1R1P A;  2HDX A;  5DC9 A;  2XP1 A;  1AOT F;  1O4O A;  1UUS A;  3IMJ A;  3OVE A;  1LUN A;  3IN7 A;  3CD3 A;  4TZI A;  2DLZ A;  2H5K A;  4M4Z A;  3KFJ A;  5CDW A;  1O4P A;  2RMX A;  4LUE A;  1HCT B;  1FBV A;  3HIZ B;  1BLJ A;  1BKM A;  1A1E A;  3GXW A;  1P13 A;  4A4C A;  1X27 A;  5DC4 A;  2HUW A;  2DX0 A;  1SPR A;  3BUX B;  3EAC A;  5AUL A;  3QWX X;  3C7I A;  1F1W A;  1O4K A;  2K79 B;  1NRV A;  3US4 A;  3OV1 A;  3VRO A;  1O43 A;  4OHD A;  1O4R A;  1RPY A;  1JWO A;  4GPL B;  3M7F A;  2MK2 A;  2MQI A;  2IUI A;  2B3O A;  1AOU F;  2ROR A;  2CR4 A;  1SHB A;  1A1C A;  1D4T A;  1FMK A;  1YVH A;  1JYQ A;  3WA4 A;  3ZNI A;  1D4W A;  2EL8 A;  2JYQ A;  3N84 A;  2IUH A;  4JE4 A;  1O49 A;  2KK6 A;  1FHS A;  1O4Q A;  2AUG A;  1BFJ A;  1KSW A;  2H46 E;  2L6K A;  3S9K A;  4FL2 A;  2EO6 A;  3N7Y A;  5D0J A;  4L1B B;  1LCK A;  1F2F A;  4QSY A;  1BMB A;  1MW4 A;  2DCR A;  2ETZ A;  1BM2 A;  1RQQ C;  5GJI A;  1RJA A;  5EG3 B;  5IBS A;  1HCS B; 
#chains in the Genus database with same CATH topology
 1O4H A;  5DC0 B;  1O4I A;  3UF4 A;  1BKL A;  3QWY A;  1IJR A;  1O47 A;  1R1S A;  4GWF A;  2K7A B;  2CRH A;  1X0N A;  4WWQ A;  2C9W A;  1BG1 A;  3PLF B;  1O46 A;  3BKB A;  3TKZ A;  1WQU A;  4D8K A;  1SHA A;  3GXX A;  1AB2 A;  5DF6 A;  4EY0 A;  1BF5 A;  2HMH A;  2SHP A;  3HHM B;  2QMS A;  3VGO A;  1LUK A;  4ROJ A;  5AXI A;  3HCK A;  3PSJ A;  4XZ0 A;  1B47 A;  3PSK A;  3S8L A;  1PIC A;  1A81 A;  1K9A A;  1Z3K A;  3PQZ A;  5EEL A;  5EHR A;  1FYR A;  2LCT A;  5KAZ A;  1NZV A;  1ZFP E;  4NWF A;  1FU5 A;  1YVL A;  3BUO B;  1QCF A;  1KA6 A;  3CXL A;  3MXY A;  4FBN A;  2CS0 A;  1OPK A;  1OO3 A;  1O4E A;  4DGX A;  1TCE A;  2AOB A;  4F5B A;  4OHL A;  1QAD A;  1JYR A;  1QG1 E;  2LNX A;  2OZO A;  3EAZ A;  4JGH A;  2LQW A;  3K2T A;  1FU6 A;  5EHP A;  1D1Z A;  1JU5 A;  3BUW B;  2L4K A;  2SRC A;  4E93 A;  2LQN A;  5HKZ A;  5I6V A;  4K45 A;  3OP0 A;  3TL0 A;  1KA7 A;  1Y1U A;  3VS5 A;  3VS2 A;  2FO0 A;  3MXC A;  4XZ1 A;  4H1O A;  1AYB A;  4OHE A;  2EYZ A;  3VS7 A;  4H34 A;  3VRQ A;  3OB2 B;  4LUD A;  2YSX A;  1O4N A;  3IN8 A;  5GJH A;  1AD5 A;  4K11 A;  1O4B A;  2EKX A;  2HCK A;  5IBM A;  3OB1 B;  1I3Z A;  1NZL A;  1O4J A;  2GSB A;  2RSY A;  2DLY A;  1O4C A;  1GRI A;  4DGP A;  4U17 A;  3BUM B;  2MC1 A;  1R1Q A;  2PLD A;  3VS4 A;  1GHU A;  3VS1 A;  2PLE A;  1JYU A;  3MAZ A;  4A4B A;  5J3X A;  1LCJ A;  2KGY A;  1MIL A;  3VRY A;  3LYV A;  2GE9 A;  1O44 A;  3K2M A;  2RVF A;  1LKK A;  1LKL A;  1O45 A;  1O42 A;  4P9V A;  1UUR A;  1M61 A;  1CJ1 A;  1CWD L;  2PTK A;  3VS6 A;  3PJP A;  3CBL A;  1LUM A;  2YU7 A;  2H8H A;  1O4A A;  4P9Z A;  2Y3A B;  1O4L A;  4X6S A;  2AOA A;  1Y57 A;  2L3T A;  1A09 A;  1A1A A;  3N8M A;  1CWE A;  4OHI A;  3VRR A;  2IUG A;  1X6C A;  2EOB A;  2EO3 A;  1BLK A;  5HKW A;  2DM0 A;  2LNW A;  4F5A A;  5EEQ A;  1BHF A;  2FCI A;  2VIF A;  1SHD A;  2Y1M A;  2CI8 A;  2Y1N A;  4EIH A;  1A08 A;  1O4G A;  5HKY A;  3CWG A;  2OQ1 A;  2DVJ A;  1IS0 A;  3S8N A;  3BUN B;  3IMD A;  3PS5 A;  1AYC A;  2EU0 A;  3T04 A;  2ABL A;  3UYO A;  2PNB A;  5BO4 A;  1M27 A;  1OPL A;  2BBU A;  3VRP A;  4F59 A;  1H9O A;  1KC2 A;  2EYV A;  3VS3 A;  1AYD A;  1CSZ A;  1O4D A;  3VRZ A;  1FBZ A;  1BFI A;  3S8O A;  2CI9 A;  2CIA A;  4OHH A;  1O48 A;  2MRK A;  2HDV A;  2ECD A;  2C0T A;  3GQI B;  1BHH A;  1SKJ A;  4K44 A;  1O4F A;  2CBL A;  3VRN A;  1LUI A;  2EYY A;  2C0I A;  1TZE E;  1O41 A;  1XA6 A;  1A1B A;  2PNA A;  4NWG A;  4FL3 A;  1G83 A;  1AYA A;  4GL9 E;  4K2R A;  1A07 A;  4JEG A;  2MRJ A;  3VS0 A;  1CSY A;  2C0O A;  3PFV A;  4U1P A;  1SPS A;  1BHH B;  2IZV A;  1OO4 A;  1O4M A;  3NHN A;  2KNO A;  4E68 A;  1R1P A;  2HDX A;  5DC9 A;  2XP1 A;  1AOT F;  1O4O A;  1UUS A;  3IMJ A;  3OVE A;  1LUN A;  3IN7 A;  3CD3 A;  4TZI A;  2DLZ A;  2H5K A;  4M4Z A;  3KFJ A;  5CDW A;  1O4P A;  2RMX A;  4LUE A;  1HCT B;  1FBV A;  3HIZ B;  1BLJ A;  1BKM A;  1A1E A;  3GXW A;  1P13 A;  4A4C A;  1X27 A;  5DC4 A;  2HUW A;  2DX0 A;  1SPR A;  3BUX B;  3EAC A;  5AUL A;  3QWX X;  3C7I A;  1F1W A;  1O4K A;  2K79 B;  1NRV A;  3US4 A;  3OV1 A;  3VRO A;  1O43 A;  4OHD A;  1O4R A;  1RPY A;  1JWO A;  4GPL B;  3M7F A;  2MK2 A;  2MQI A;  2IUI A;  2B3O A;  1AOU F;  2ROR A;  2CR4 A;  1SHB A;  1A1C A;  1D4T A;  1FMK A;  1YVH A;  1JYQ A;  3WA4 A;  3ZNI A;  1D4W A;  2EL8 A;  2JYQ A;  3N84 A;  2IUH A;  4JE4 A;  1O49 A;  2KK6 A;  1FHS A;  1O4Q A;  2AUG A;  1BFJ A;  1KSW A;  2H46 E;  2L6K A;  3S9K A;  4FL2 A;  2EO6 A;  3N7Y A;  5D0J A;  4L1B B;  1LCK A;  1F2F A;  4QSY A;  1BMB A;  1MW4 A;  2DCR A;  2ETZ A;  1BM2 A;  1RQQ C;  5GJI A;  1RJA A;  2LRA A;  5EG3 B;  5IBS A;  1HCS B; 
#chains in the Genus database with same CATH homology
 1O4H A;  5DC0 B;  1O4I A;  3UF4 A;  1BKL A;  3QWY A;  1IJR A;  1O47 A;  1R1S A;  4GWF A;  2K7A B;  2CRH A;  1X0N A;  4WWQ A;  2C9W A;  1BG1 A;  3PLF B;  1O46 A;  3BKB A;  3TKZ A;  1WQU A;  4D8K A;  1SHA A;  3GXX A;  1AB2 A;  5DF6 A;  4EY0 A;  1BF5 A;  2HMH A;  2SHP A;  3HHM B;  2QMS A;  3VGO A;  1LUK A;  4ROJ A;  5AXI A;  3HCK A;  3PSJ A;  4XZ0 A;  1B47 A;  3PSK A;  3S8L A;  1PIC A;  1A81 A;  1K9A A;  1Z3K A;  3PQZ A;  5EEL A;  5EHR A;  1FYR A;  2LCT A;  5KAZ A;  1NZV A;  1ZFP E;  4NWF A;  1FU5 A;  1YVL A;  3BUO B;  1QCF A;  1KA6 A;  3CXL A;  3MXY A;  4FBN A;  2CS0 A;  1OPK A;  1OO3 A;  1O4E A;  4DGX A;  1TCE A;  2AOB A;  4F5B A;  4OHL A;  1QAD A;  1JYR A;  1QG1 E;  2LNX A;  2OZO A;  3EAZ A;  4JGH A;  2LQW A;  1FU6 A;  5EHP A;  1D1Z A;  1JU5 A;  3BUW B;  2L4K A;  2SRC A;  4E93 A;  2LQN A;  5HKZ A;  5I6V A;  4K45 A;  3OP0 A;  3TL0 A;  1KA7 A;  1Y1U A;  3VS5 A;  3VS2 A;  2FO0 A;  3MXC A;  4XZ1 A;  4H1O A;  1AYB A;  4OHE A;  2EYZ A;  3VS7 A;  4H34 A;  3VRQ A;  3OB2 B;  4LUD A;  2YSX A;  1O4N A;  3IN8 A;  5GJH A;  1AD5 A;  4K11 A;  1O4B A;  2EKX A;  2HCK A;  5IBM A;  3OB1 B;  1I3Z A;  1NZL A;  1O4J A;  2GSB A;  2RSY A;  2DLY A;  1O4C A;  1GRI A;  4DGP A;  4U17 A;  3BUM B;  2MC1 A;  1R1Q A;  2PLD A;  3VS4 A;  1GHU A;  3VS1 A;  2PLE A;  1JYU A;  3MAZ A;  4A4B A;  5J3X A;  1LCJ A;  1MIL A;  3VRY A;  2GE9 A;  1O44 A;  3K2M A;  2RVF A;  1LKK A;  1LKL A;  1O45 A;  1O42 A;  4P9V A;  1UUR A;  1M61 A;  1CJ1 A;  1CWD L;  2PTK A;  3VS6 A;  3PJP A;  3CBL A;  1LUM A;  2YU7 A;  2H8H A;  1O4A A;  4P9Z A;  2Y3A B;  1O4L A;  4X6S A;  2AOA A;  1Y57 A;  2L3T A;  1A09 A;  1A1A A;  3N8M A;  1CWE A;  4OHI A;  3VRR A;  2IUG A;  1X6C A;  2EOB A;  2EO3 A;  1BLK A;  5HKW A;  2DM0 A;  2LNW A;  4F5A A;  5EEQ A;  1BHF A;  2FCI A;  2VIF A;  1SHD A;  2Y1M A;  2CI8 A;  2Y1N A;  4EIH A;  1A08 A;  1O4G A;  5HKY A;  3CWG A;  2OQ1 A;  2DVJ A;  1IS0 A;  3S8N A;  3BUN B;  3IMD A;  3PS5 A;  1AYC A;  2EU0 A;  3T04 A;  2ABL A;  3UYO A;  2PNB A;  5BO4 A;  1M27 A;  1OPL A;  2BBU A;  3VRP A;  4F59 A;  1H9O A;  1KC2 A;  2EYV A;  3VS3 A;  1AYD A;  1CSZ A;  1O4D A;  3VRZ A;  1FBZ A;  1BFI A;  3S8O A;  2CI9 A;  2CIA A;  4OHH A;  1O48 A;  2MRK A;  2HDV A;  2ECD A;  2C0T A;  3GQI B;  1BHH A;  1SKJ A;  4K44 A;  1O4F A;  2CBL A;  3VRN A;  1LUI A;  2EYY A;  2C0I A;  1TZE E;  1O41 A;  1XA6 A;  1A1B A;  2PNA A;  4NWG A;  4FL3 A;  1G83 A;  1AYA A;  4GL9 E;  4K2R A;  1A07 A;  4JEG A;  2MRJ A;  3VS0 A;  1CSY A;  2C0O A;  3PFV A;  4U1P A;  1SPS A;  1BHH B;  2IZV A;  1OO4 A;  1O4M A;  3NHN A;  2KNO A;  4E68 A;  1R1P A;  2HDX A;  5DC9 A;  2XP1 A;  1AOT F;  1O4O A;  1UUS A;  3IMJ A;  3OVE A;  1LUN A;  3IN7 A;  3CD3 A;  4TZI A;  2DLZ A;  2H5K A;  4M4Z A;  3KFJ A;  5CDW A;  1O4P A;  2RMX A;  4LUE A;  1HCT B;  1FBV A;  3HIZ B;  1BLJ A;  1BKM A;  1A1E A;  3GXW A;  1P13 A;  4A4C A;  1X27 A;  5DC4 A;  2HUW A;  2DX0 A;  1SPR A;  3BUX B;  3EAC A;  5AUL A;  3QWX X;  3C7I A;  1F1W A;  1O4K A;  2K79 B;  1NRV A;  3US4 A;  3OV1 A;  3VRO A;  1O43 A;  4OHD A;  1O4R A;  1RPY A;  1JWO A;  4GPL B;  3M7F A;  2MK2 A;  2MQI A;  2IUI A;  2B3O A;  1AOU F;  2ROR A;  2CR4 A;  1SHB A;  1A1C A;  1D4T A;  1FMK A;  1YVH A;  1JYQ A;  3WA4 A;  3ZNI A;  1D4W A;  2EL8 A;  2JYQ A;  3N84 A;  2IUH A;  4JE4 A;  1O49 A;  2KK6 A;  1FHS A;  1O4Q A;  2AUG A;  1BFJ A;  1KSW A;  2H46 E;  2L6K A;  3S9K A;  4FL2 A;  2EO6 A;  3N7Y A;  5D0J A;  4L1B B;  1LCK A;  1F2F A;  4QSY A;  1BMB A;  1MW4 A;  2DCR A;  2ETZ A;  1BM2 A;  1RQQ C;  5GJI A;  1RJA A;  5EG3 B;  5IBS A;  1HCS B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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