3IMDA

Crystal structure of the grb2 sh2 domain in complex with a flexible ac-py-q-n-nh2 tripeptide mimic
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
101
structure length
101
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 23
structure length 101
sequence length 101
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3imdA00
2MQIA 4A4BA 4OHDA 3C7IA 1O4BA 1BHHA 2RMXA 1SPSA 2ECDA 1TCEA 1FU6A 3BUXB 3VS1A 3IN7A 1BLKA 3GXWA 1SHBA 3GQIB 3VRZA 3N84A 2EKXA 1O4LA 3VRQA 1A07A 2EU0A 3PQZA 3VS6A 3VS5A 1AOTF 2IUGA 1CWEA 4EY0A 1KA7A 1PICA 5HKYA 1LUKA 4P9VA 2CS0A 2CBLA 1AOUF 1O42A 1O4FA 1K9AA 5EHPA 4P9ZA 1O4IA 1O4PA 1BKMA 2CR4A 1F1WA 2YSXA 1MW4A 4JE4A 4F5AA 1YVHA 4JEGA 2PTKA 3TKZA 2OQ1A 1O4HA 3GXXA 1NRVA 2L4KA 5IBSA 4NWFA 4OHHA 1NZLA 2PNAA 1AYCA 1JYQA 1O4OA 1O4RA 2OZOA 1BFIA 4LUEA 2SRCA 2C0TA 1Y1UA 2MRKA 2C0OA 3T04A 1GRIA 2FO0A 1BMBA 5HKWA 1GHUA 4GL9E 4ROJA 2YU7A 3PJPA 1BHHB 2CI9A 4XZ1A 1IS0A 1BG1A 3QWYA 5IBMA 1RQQC 1RJAA 1O43A 2IZVA 5DC4A 5GJHA 2AOAA 3VS0A 1G83A 2XP1A 1O4EA 1SHAA 2Y1MA 1JWOA 3CD3A 1O4NA 5EEQA 1KA6A 1HCSB 2H8HA 3BUNB 5BO4A 3BKBA 3S8NA 1FU5A 1O41A 5D0JA 1FMKA 1XA6A 1O49A 4K44A 2Y3AB 1JU5A 3PFVA 1O48A 1AB2A 1X0NA 2KNOA 1IJRA 3MXCA 1D4WA 2PNBA 1QG1E 1X27A 1O44A 1Y57A 2RSYA 3VRYA 2LQNA 5KAZA 1A09A 2PLEA 1NZVA 2EYVA 2C0IA 4E93A 1LKLA 2PLDA 4DGPA 2MC1A 3WA4A 1UURA 3S9KA 2IUHA 3US4A 1BLJA 1ZFPE 1M61A 3UYOA 3IN8A 3VRNA 1O4KA 3N8MA 3CWGA 3EACA 3VRPA 5EG3B 3PSJA 3BUOB 4EIHA 2DVJA 2HCKA 4K45A 4XZ0A 1AYBA 1CSYA 2QMSA 1M27A 4DGXA 3M7FA 1AYDA 4H1OA 3HHMB 1A1BA 3OB2B 1OO4A 4F5BA 3OP0A 1OPKA 1RPYA 2L3TA 2C9WA 1LCKA 3VS7A 2DLYA 4FL2A 2MK2A 1QCFA 2L6KA 2EYZA 4FL3A 2MRJA 3N7YA 5AULA 4U1PA 4D8KA 4A4CA 1R1PA 2ABLA 1OPLA 2JYQA 2SHPA 1Z3KA 1I3ZA 3VRRA 4FBNA 1LKKA 3S8LA 1LUMA 2EL8A 1AYAA 1FBVA 2AOBA 2K79B 4X6SA 4OHEA 2DCRA 3BUWB 3HCKA 1O4CA 4JGHA 5CDWA 2ETZA 3OVEA 2H46E 3IMDA 1QADA 1A81A 1O46A 2GSBA 1BF5A 5GJIA 2LNWA 1A1EA 3MAZA 1LUIA 1KC2A 2K7AB 2HMHA 4LUDA 2EYYA 5I6VA 1FHSA 4OHLA 1TZEE 1BM2A 1SKJA 5HKZA 5J3XA 2HDVA 1BFJA 3CBLA 1CWDL 1LUNA 3VS2A 4M4ZA 2GE9A 5EHRA 4L1BB 1CJ1A 4K2RA 4GWFA 2RVFA 3PLFB 1D4TA 1HCTB 3QWXX 4WWQA 1O4DA 1CSZA 1WQUA 1LCJA 4F59A 1H9OA 3UF4A 3VS3A 3S8OA 1O45A 2RORA 2FCIA 2BBUA 1B47A 2HUWA 1SHDA 1A1CA 4QSYA 2EOBA 2LQWA 1OO3A 1SPRA 2CRHA 3VGOA 2DLZA 4K11A 4E68A 5DC0B 3EAZA 3VROA 2Y1NA 1UUSA 4H34A 2AUGA 1O4GA 1F2FA 2CIAA 1FYRA 3PS5A 1O4MA 3MXYA 1R1QA 3BUMB 3NHNA 3IMJA 4NWGA 1YVLA 3HIZB 1FBZA 1O4JA 3KFJA 2HDXA 1KSWA 1O4AA 1A08A 4GPLB 4U17A 3TL0A 3K2MA 2KK6A 4OHIA 3VS4A 2DX0A 2LNXA 1AD5A 2IUIA 4TZIA 1BKLA 5DC9A 2VIFA 1X6CA 3ZNIA 2CI8A 3OB1B 1D1ZA 1JYUA 2B3OA 1O47A 1A1AA 1JYRA 2DM0A 3OV1A 3CXLA 5DF6A 3PSKA 2LCTA 2H5KA 5EELA 5AXIA 1BHFA 1MILA 1R1SA 2EO3A 1P13A 2EO6A 1O4QA
chains in the Genus database with same CATH superfamily
2MQIA 4A4BA 4OHDA 3C7IA 1O4BA 1BHHA 2RMXA 1SPSA 2ECDA 1TCEA 1FU6A 3BUXB 3VS1A 3IN7A 1BLKA 3GXWA 1SHBA 3GQIB 3VRZA 3N84A 2EKXA 1O4LA 3VRQA 1A07A 2EU0A 3PQZA 3VS6A 3VS5A 1AOTF 2IUGA 1CWEA 4EY0A 1KA7A 1PICA 5HKYA 1LUKA 4P9VA 2CS0A 2CBLA 1AOUF 1O42A 1O4FA 1K9AA 5EHPA 4P9ZA 1O4IA 1O4PA 1BKMA 2CR4A 1F1WA 2YSXA 1MW4A 4JE4A 4F5AA 1YVHA 4JEGA 2PTKA 3TKZA 2OQ1A 1O4HA 3GXXA 1NRVA 2L4KA 5IBSA 4NWFA 4OHHA 1NZLA 2PNAA 1AYCA 1JYQA 1O4OA 1O4RA 2OZOA 1BFIA 4LUEA 2SRCA 2C0TA 1Y1UA 2MRKA 2C0OA 3T04A 1GRIA 2FO0A 1BMBA 5HKWA 1GHUA 4GL9E 4ROJA 2YU7A 3PJPA 1BHHB 2CI9A 4XZ1A 1IS0A 1BG1A 3QWYA 5IBMA 1RQQC 1RJAA 1O43A 2IZVA 5DC4A 5GJHA 2AOAA 3VS0A 1G83A 2XP1A 1O4EA 1SHAA 2Y1MA 1JWOA 3CD3A 1O4NA 5EEQA 1KA6A 1HCSB 2H8HA 3BUNB 5BO4A 3BKBA 3S8NA 1FU5A 1O41A 5D0JA 1FMKA 1XA6A 1O49A 4K44A 2Y3AB 1JU5A 3PFVA 1O48A 1AB2A 1X0NA 2KNOA 1IJRA 3MXCA 1D4WA 2PNBA 1QG1E 1X27A 1O44A 1Y57A 2RSYA 3VRYA 2LQNA 5KAZA 1A09A 2PLEA 1NZVA 2EYVA 2C0IA 4E93A 1LKLA 2PLDA 4DGPA 2MC1A 3WA4A 1UURA 3S9KA 2IUHA 3US4A 1BLJA 1ZFPE 1M61A 3UYOA 3IN8A 3VRNA 1O4KA 3N8MA 3CWGA 3EACA 3VRPA 5EG3B 3PSJA 3BUOB 4EIHA 2DVJA 2HCKA 4K45A 4XZ0A 1AYBA 1CSYA 2QMSA 1M27A 4DGXA 3M7FA 1AYDA 4H1OA 3HHMB 1A1BA 3OB2B 1OO4A 4F5BA 3OP0A 1OPKA 1RPYA 2L3TA 2C9WA 1LCKA 3VS7A 2DLYA 4FL2A 2MK2A 1QCFA 2L6KA 2EYZA 4FL3A 2MRJA 3N7YA 5AULA 4U1PA 4D8KA 4A4CA 1R1PA 2ABLA 1OPLA 2JYQA 2SHPA 1Z3KA 1I3ZA 3VRRA 4FBNA 1LKKA 3S8LA 1LUMA 2EL8A 1AYAA 1FBVA 2AOBA 2K79B 4X6SA 4OHEA 2DCRA 3BUWB 3HCKA 1O4CA 4JGHA 5CDWA 2ETZA 3OVEA 2H46E 3IMDA 1QADA 1A81A 1O46A 2GSBA 1BF5A 5GJIA 2LNWA 1A1EA 3MAZA 1LUIA 1KC2A 2K7AB 2HMHA 4LUDA 2EYYA 5I6VA 1FHSA 4OHLA 1TZEE 1BM2A 1SKJA 5HKZA 5J3XA 2HDVA 1BFJA 3CBLA 1CWDL 1LUNA 3VS2A 4M4ZA 2GE9A 5EHRA 4L1BB 1CJ1A 4K2RA 4GWFA 2RVFA 3PLFB 1D4TA 1HCTB 3QWXX 4WWQA 1O4DA 1CSZA 1WQUA 1LCJA 4F59A 1H9OA 3UF4A 3VS3A 3S8OA 3K2TA 1O45A 2RORA 2FCIA 2BBUA 1B47A 2HUWA 1SHDA 1A1CA 4QSYA 2EOBA 2LQWA 1OO3A 1SPRA 2CRHA 3VGOA 2DLZA 4K11A 4E68A 5DC0B 3EAZA 3VROA 2Y1NA 1UUSA 4H34A 3LYVA 2KGYA 2AUGA 1O4GA 1F2FA 2CIAA 1FYRA 3PS5A 1O4MA 3MXYA 1R1QA 3BUMB 3NHNA 3IMJA 4NWGA 1YVLA 3HIZB 1FBZA 1O4JA 3KFJA 2HDXA 1KSWA 1O4AA 1A08A 4GPLB 4U17A 3TL0A 3K2MA 2KK6A 4OHIA 3VS4A 2DX0A 2LNXA 1AD5A 2IUIA 4TZIA 1BKLA 5DC9A 2VIFA 1X6CA 3ZNIA 2CI8A 3OB1B 1D1ZA 1JYUA 2B3OA 1O47A 1A1AA 1JYRA 2DM0A 3OV1A 3CXLA 5DF6A 3PSKA 2LCTA 2LRAA 2H5KA 5EELA 5AXIA 1BHFA 1MILA 1R1SA 2EO3A 1P13A 2EO6A 1O4QA
chains in the Genus database with same CATH topology
2MQIA 4A4BA 4OHDA 3C7IA 1O4BA 1BHHA 2RMXA 1SPSA 2ECDA 1TCEA 1FU6A 3BUXB 3VS1A 3IN7A 1BLKA 3GXWA 1SHBA 3GQIB 3VRZA 3N84A 2EKXA 1O4LA 3VRQA 1A07A 2EU0A 3PQZA 3VS6A 3VS5A 1AOTF 2IUGA 1CWEA 4EY0A 1KA7A 1PICA 5HKYA 1LUKA 4P9VA 2CS0A 2CBLA 1AOUF 1O42A 1O4FA 1K9AA 5EHPA 4P9ZA 1O4IA 1O4PA 1BKMA 2CR4A 1F1WA 2YSXA 1MW4A 4JE4A 4F5AA 1YVHA 4JEGA 2PTKA 3TKZA 2OQ1A 1O4HA 3GXXA 1NRVA 2L4KA 5IBSA 4NWFA 4OHHA 1NZLA 2PNAA 1AYCA 1JYQA 1O4OA 1O4RA 2OZOA 1BFIA 4LUEA 2SRCA 2C0TA 1Y1UA 2MRKA 2C0OA 3T04A 1GRIA 2FO0A 1BMBA 5HKWA 1GHUA 4GL9E 4ROJA 2YU7A 3PJPA 1BHHB 2CI9A 4XZ1A 1IS0A 1BG1A 3QWYA 5IBMA 1RQQC 1RJAA 1O43A 2IZVA 5DC4A 5GJHA 2AOAA 3VS0A 1G83A 2XP1A 1O4EA 1SHAA 2Y1MA 1JWOA 3CD3A 1O4NA 5EEQA 1KA6A 1HCSB 2H8HA 3BUNB 5BO4A 3BKBA 3S8NA 1FU5A 1O41A 5D0JA 1FMKA 1XA6A 1O49A 4K44A 2Y3AB 1JU5A 3PFVA 1O48A 1AB2A 1X0NA 2KNOA 1IJRA 3MXCA 1D4WA 2PNBA 1QG1E 1X27A 1O44A 1Y57A 2RSYA 3VRYA 2LQNA 5KAZA 1A09A 2PLEA 1NZVA 2EYVA 2C0IA 4E93A 1LKLA 2PLDA 4DGPA 2MC1A 3WA4A 1UURA 3S9KA 2IUHA 3US4A 1BLJA 1ZFPE 1M61A 3UYOA 3IN8A 3VRNA 1O4KA 3N8MA 3CWGA 3EACA 3VRPA 5EG3B 3PSJA 3BUOB 4EIHA 2DVJA 2HCKA 4K45A 4XZ0A 1AYBA 1CSYA 2QMSA 1M27A 4DGXA 3M7FA 1AYDA 4H1OA 3HHMB 1A1BA 3OB2B 1OO4A 4F5BA 3OP0A 1OPKA 1RPYA 2L3TA 2C9WA 1LCKA 3VS7A 2DLYA 4FL2A 2MK2A 1QCFA 2L6KA 2EYZA 4FL3A 2MRJA 3N7YA 5AULA 4U1PA 4D8KA 4A4CA 1R1PA 2ABLA 1OPLA 2JYQA 2SHPA 1Z3KA 1I3ZA 3VRRA 4FBNA 1LKKA 3S8LA 1LUMA 2EL8A 1AYAA 1FBVA 2AOBA 2K79B 4X6SA 4OHEA 2DCRA 3BUWB 3HCKA 1O4CA 4JGHA 5CDWA 2ETZA 3OVEA 2H46E 3IMDA 1QADA 1A81A 1O46A 2GSBA 1BF5A 5GJIA 2LNWA 1A1EA 3MAZA 1LUIA 1KC2A 2K7AB 2HMHA 4LUDA 2EYYA 5I6VA 1FHSA 4OHLA 1TZEE 1BM2A 1SKJA 5HKZA 5J3XA 2HDVA 1BFJA 3CBLA 1CWDL 1LUNA 3VS2A 4M4ZA 2GE9A 5EHRA 4L1BB 1CJ1A 4K2RA 4GWFA 2RVFA 3PLFB 1D4TA 1HCTB 3QWXX 4WWQA 1O4DA 1CSZA 1WQUA 1LCJA 4F59A 1H9OA 3UF4A 3VS3A 3S8OA 1O45A 2RORA 2FCIA 2BBUA 1B47A 2HUWA 1SHDA 1A1CA 4QSYA 2EOBA 2LQWA 1OO3A 1SPRA 2CRHA 3VGOA 2DLZA 4K11A 4E68A 5DC0B 3EAZA 3VROA 2Y1NA 1UUSA 4H34A 2AUGA 1O4GA 1F2FA 2CIAA 1FYRA 3PS5A 1O4MA 3MXYA 1R1QA 3BUMB 3NHNA 3IMJA 4NWGA 1YVLA 3HIZB 1FBZA 1O4JA 3KFJA 2HDXA 1KSWA 1O4AA 1A08A 4GPLB 4U17A 3TL0A 3K2MA 2KK6A 4OHIA 3VS4A 2DX0A 2LNXA 1AD5A 2IUIA 4TZIA 1BKLA 5DC9A 2VIFA 1X6CA 3ZNIA 2CI8A 3OB1B 1D1ZA 1JYUA 2B3OA 1O47A 1A1AA 1JYRA 2DM0A 3OV1A 3CXLA 5DF6A 3PSKA 2LCTA 2H5KA 5EELA 5AXIA 1BHFA 1MILA 1R1SA 2EO3A 1P13A 2EO6A 1O4QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MQI A;  4A4B A;  4OHD A;  3C7I A;  1O4B A;  1BHH A;  2RMX A;  1SPS A;  2ECD A;  1TCE A;  1FU6 A;  3BUX B;  3VS1 A;  3IN7 A;  1BLK A;  3GXW A;  1SHB A;  3GQI B;  3VRZ A;  3N84 A;  2EKX A;  1O4L A;  3VRQ A;  1A07 A;  2EU0 A;  3PQZ A;  3VS6 A;  3VS5 A;  1AOT F;  2IUG A;  1CWE A;  4EY0 A;  1KA7 A;  1PIC A;  5HKY A;  1LUK A;  4P9V A;  2CS0 A;  2CBL A;  1AOU F;  1O42 A;  1O4F A;  1K9A A;  5EHP A;  4P9Z A;  1O4I A;  1O4P A;  1BKM A;  2CR4 A;  1F1W A;  2YSX A;  1MW4 A;  4JE4 A;  4F5A A;  1YVH A;  4JEG A;  2PTK A;  3TKZ A;  2OQ1 A;  1O4H A;  3GXX A;  1NRV A;  2L4K A;  5IBS A;  4NWF A;  4OHH A;  1NZL A;  2PNA A;  1AYC A;  1JYQ A;  1O4O A;  1O4R A;  2OZO A;  1BFI A;  4LUE A;  2SRC A;  2C0T A;  1Y1U A;  2MRK A;  2C0O A;  3T04 A;  1GRI A;  2FO0 A;  1BMB A;  5HKW A;  1GHU A;  4GL9 E;  4ROJ A;  2YU7 A;  3PJP A;  1BHH B;  2CI9 A;  4XZ1 A;  1IS0 A;  1BG1 A;  3QWY A;  5IBM A;  1RQQ C;  1RJA A;  1O43 A;  2IZV A;  5DC4 A;  5GJH A;  2AOA A;  3VS0 A;  1G83 A;  2XP1 A;  1O4E A;  1SHA A;  2Y1M A;  1JWO A;  3CD3 A;  1O4N A;  5EEQ A;  1KA6 A;  1HCS B;  2H8H A;  3BUN B;  5BO4 A;  3BKB A;  3S8N A;  1FU5 A;  1O41 A;  5D0J A;  1FMK A;  1XA6 A;  1O49 A;  4K44 A;  2Y3A B;  1JU5 A;  3PFV A;  1O48 A;  1AB2 A;  1X0N A;  2KNO A;  1IJR A;  3MXC A;  1D4W A;  2PNB A;  1QG1 E;  1X27 A;  1O44 A;  1Y57 A;  2RSY A;  3VRY A;  2LQN A;  5KAZ A;  1A09 A;  2PLE A;  1NZV A;  2EYV A;  2C0I A;  4E93 A;  1LKL A;  2PLD A;  4DGP A;  2MC1 A;  3WA4 A;  1UUR A;  3S9K A;  2IUH A;  3US4 A;  1BLJ A;  1ZFP E;  1M61 A;  3UYO A;  3IN8 A;  3VRN A;  1O4K A;  3N8M A;  3CWG A;  3EAC A;  3VRP A;  5EG3 B;  3PSJ A;  3BUO B;  4EIH A;  2DVJ A;  2HCK A;  4K45 A;  4XZ0 A;  1AYB A;  1CSY A;  2QMS A;  1M27 A;  4DGX A;  3M7F A;  1AYD A;  4H1O A;  3HHM B;  1A1B A;  3OB2 B;  1OO4 A;  4F5B A;  3OP0 A;  1OPK A;  1RPY A;  2L3T A;  2C9W A;  1LCK A;  3VS7 A;  2DLY A;  4FL2 A;  2MK2 A;  1QCF A;  2L6K A;  2EYZ A;  4FL3 A;  2MRJ A;  3N7Y A;  5AUL A;  4U1P A;  4D8K A;  4A4C A;  1R1P A;  2ABL A;  1OPL A;  2JYQ A;  2SHP A;  1Z3K A;  1I3Z A;  3VRR A;  4FBN A;  1LKK A;  3S8L A;  1LUM A;  2EL8 A;  1AYA A;  1FBV A;  2AOB A;  2K79 B;  4X6S A;  4OHE A;  2DCR A;  3BUW B;  3HCK A;  1O4C A;  4JGH A;  5CDW A;  2ETZ A;  3OVE A;  2H46 E;  3IMD A;  1QAD A;  1A81 A;  1O46 A;  2GSB A;  1BF5 A;  5GJI A;  2LNW A;  1A1E A;  3MAZ A;  1LUI A;  1KC2 A;  2K7A B;  2HMH A;  4LUD A;  2EYY A;  5I6V A;  1FHS A;  4OHL A;  1TZE E;  1BM2 A;  1SKJ A;  5HKZ A;  5J3X A;  2HDV A;  1BFJ A;  3CBL A;  1CWD L;  1LUN A;  3VS2 A;  4M4Z A;  2GE9 A;  5EHR A;  4L1B B;  1CJ1 A;  4K2R A;  4GWF A;  2RVF A;  3PLF B;  1D4T A;  1HCT B;  3QWX X;  4WWQ A;  1O4D A;  1CSZ A;  1WQU A;  1LCJ A;  4F59 A;  1H9O A;  3UF4 A;  3VS3 A;  3S8O A;  1O45 A;  2ROR A;  2FCI A;  2BBU A;  1B47 A;  2HUW A;  1SHD A;  1A1C A;  4QSY A;  2EOB A;  2LQW A;  1OO3 A;  1SPR A;  2CRH A;  3VGO A;  2DLZ A;  4K11 A;  4E68 A;  5DC0 B;  3EAZ A;  3VRO A;  2Y1N A;  1UUS A;  4H34 A;  2AUG A;  1O4G A;  1F2F A;  2CIA A;  1FYR A;  3PS5 A;  1O4M A;  3MXY A;  1R1Q A;  3BUM B;  3NHN A;  3IMJ A;  4NWG A;  1YVL A;  3HIZ B;  1FBZ A;  1O4J A;  3KFJ A;  2HDX A;  1KSW A;  1O4A A;  1A08 A;  4GPL B;  4U17 A;  3TL0 A;  3K2M A;  2KK6 A;  4OHI A;  3VS4 A;  2DX0 A;  2LNX A;  1AD5 A;  2IUI A;  4TZI A;  1BKL A;  5DC9 A;  2VIF A;  1X6C A;  3ZNI A;  2CI8 A;  3OB1 B;  1D1Z A;  1JYU A;  2B3O A;  1O47 A;  1A1A A;  1JYR A;  2DM0 A;  3OV1 A;  3CXL A;  5DF6 A;  3PSK A;  2LCT A;  2H5K A;  5EEL A;  5AXI A;  1BHF A;  1MIL A;  1R1S A;  2EO3 A;  1P13 A;  2EO6 A;  1O4Q A; 
#chains in the Genus database with same CATH topology
 2MQI A;  4A4B A;  4OHD A;  3C7I A;  1O4B A;  1BHH A;  2RMX A;  1SPS A;  2ECD A;  1TCE A;  1FU6 A;  3BUX B;  3VS1 A;  3IN7 A;  1BLK A;  3GXW A;  1SHB A;  3GQI B;  3VRZ A;  3N84 A;  2EKX A;  1O4L A;  3VRQ A;  1A07 A;  2EU0 A;  3PQZ A;  3VS6 A;  3VS5 A;  1AOT F;  2IUG A;  1CWE A;  4EY0 A;  1KA7 A;  1PIC A;  5HKY A;  1LUK A;  4P9V A;  2CS0 A;  2CBL A;  1AOU F;  1O42 A;  1O4F A;  1K9A A;  5EHP A;  4P9Z A;  1O4I A;  1O4P A;  1BKM A;  2CR4 A;  1F1W A;  2YSX A;  1MW4 A;  4JE4 A;  4F5A A;  1YVH A;  4JEG A;  2PTK A;  3TKZ A;  2OQ1 A;  1O4H A;  3GXX A;  1NRV A;  2L4K A;  5IBS A;  4NWF A;  4OHH A;  1NZL A;  2PNA A;  1AYC A;  1JYQ A;  1O4O A;  1O4R A;  2OZO A;  1BFI A;  4LUE A;  2SRC A;  2C0T A;  1Y1U A;  2MRK A;  2C0O A;  3T04 A;  1GRI A;  2FO0 A;  1BMB A;  5HKW A;  1GHU A;  4GL9 E;  4ROJ A;  2YU7 A;  3PJP A;  1BHH B;  2CI9 A;  4XZ1 A;  1IS0 A;  1BG1 A;  3QWY A;  5IBM A;  1RQQ C;  1RJA A;  1O43 A;  2IZV A;  5DC4 A;  5GJH A;  2AOA A;  3VS0 A;  1G83 A;  2XP1 A;  1O4E A;  1SHA A;  2Y1M A;  1JWO A;  3CD3 A;  1O4N A;  5EEQ A;  1KA6 A;  1HCS B;  2H8H A;  3BUN B;  5BO4 A;  3BKB A;  3S8N A;  1FU5 A;  1O41 A;  5D0J A;  1FMK A;  1XA6 A;  1O49 A;  4K44 A;  2Y3A B;  1JU5 A;  3PFV A;  1O48 A;  1AB2 A;  1X0N A;  2KNO A;  1IJR A;  3MXC A;  1D4W A;  2PNB A;  1QG1 E;  1X27 A;  1O44 A;  1Y57 A;  2RSY A;  3VRY A;  2LQN A;  5KAZ A;  1A09 A;  2PLE A;  1NZV A;  2EYV A;  2C0I A;  4E93 A;  1LKL A;  2PLD A;  4DGP A;  2MC1 A;  3WA4 A;  1UUR A;  3S9K A;  2IUH A;  3US4 A;  1BLJ A;  1ZFP E;  1M61 A;  3UYO A;  3IN8 A;  3VRN A;  1O4K A;  3N8M A;  3CWG A;  3EAC A;  3VRP A;  5EG3 B;  3PSJ A;  3BUO B;  4EIH A;  2DVJ A;  2HCK A;  4K45 A;  4XZ0 A;  1AYB A;  1CSY A;  2QMS A;  1M27 A;  4DGX A;  3M7F A;  1AYD A;  4H1O A;  3HHM B;  1A1B A;  3OB2 B;  1OO4 A;  4F5B A;  3OP0 A;  1OPK A;  1RPY A;  2L3T A;  2C9W A;  1LCK A;  3VS7 A;  2DLY A;  4FL2 A;  2MK2 A;  1QCF A;  2L6K A;  2EYZ A;  4FL3 A;  2MRJ A;  3N7Y A;  5AUL A;  4U1P A;  4D8K A;  4A4C A;  1R1P A;  2ABL A;  1OPL A;  2JYQ A;  2SHP A;  1Z3K A;  1I3Z A;  3VRR A;  4FBN A;  1LKK A;  3S8L A;  1LUM A;  2EL8 A;  1AYA A;  1FBV A;  2AOB A;  2K79 B;  4X6S A;  4OHE A;  2DCR A;  3BUW B;  3HCK A;  1O4C A;  4JGH A;  5CDW A;  2ETZ A;  3OVE A;  2H46 E;  3IMD A;  1QAD A;  1A81 A;  1O46 A;  2GSB A;  1BF5 A;  5GJI A;  2LNW A;  1A1E A;  3MAZ A;  1LUI A;  1KC2 A;  2K7A B;  2HMH A;  4LUD A;  2EYY A;  5I6V A;  1FHS A;  4OHL A;  1TZE E;  1BM2 A;  1SKJ A;  5HKZ A;  5J3X A;  2HDV A;  1BFJ A;  3CBL A;  1CWD L;  1LUN A;  3VS2 A;  4M4Z A;  2GE9 A;  5EHR A;  4L1B B;  1CJ1 A;  4K2R A;  4GWF A;  2RVF A;  3PLF B;  1D4T A;  1HCT B;  3QWX X;  4WWQ A;  1O4D A;  1CSZ A;  1WQU A;  1LCJ A;  4F59 A;  1H9O A;  3UF4 A;  3VS3 A;  3S8O A;  3K2T A;  1O45 A;  2ROR A;  2FCI A;  2BBU A;  1B47 A;  2HUW A;  1SHD A;  1A1C A;  4QSY A;  2EOB A;  2LQW A;  1OO3 A;  1SPR A;  2CRH A;  3VGO A;  2DLZ A;  4K11 A;  4E68 A;  5DC0 B;  3EAZ A;  3VRO A;  2Y1N A;  1UUS A;  4H34 A;  3LYV A;  2KGY A;  2AUG A;  1O4G A;  1F2F A;  2CIA A;  1FYR A;  3PS5 A;  1O4M A;  3MXY A;  1R1Q A;  3BUM B;  3NHN A;  3IMJ A;  4NWG A;  1YVL A;  3HIZ B;  1FBZ A;  1O4J A;  3KFJ A;  2HDX A;  1KSW A;  1O4A A;  1A08 A;  4GPL B;  4U17 A;  3TL0 A;  3K2M A;  2KK6 A;  4OHI A;  3VS4 A;  2DX0 A;  2LNX A;  1AD5 A;  2IUI A;  4TZI A;  1BKL A;  5DC9 A;  2VIF A;  1X6C A;  3ZNI A;  2CI8 A;  3OB1 B;  1D1Z A;  1JYU A;  2B3O A;  1O47 A;  1A1A A;  1JYR A;  2DM0 A;  3OV1 A;  3CXL A;  5DF6 A;  3PSK A;  2LCT A;  2LRA A;  2H5K A;  5EEL A;  5AXI A;  1BHF A;  1MIL A;  1R1S A;  2EO3 A;  1P13 A;  2EO6 A;  1O4Q A; 
#chains in the Genus database with same CATH homology
 2MQI A;  4A4B A;  4OHD A;  3C7I A;  1O4B A;  1BHH A;  2RMX A;  1SPS A;  2ECD A;  1TCE A;  1FU6 A;  3BUX B;  3VS1 A;  3IN7 A;  1BLK A;  3GXW A;  1SHB A;  3GQI B;  3VRZ A;  3N84 A;  2EKX A;  1O4L A;  3VRQ A;  1A07 A;  2EU0 A;  3PQZ A;  3VS6 A;  3VS5 A;  1AOT F;  2IUG A;  1CWE A;  4EY0 A;  1KA7 A;  1PIC A;  5HKY A;  1LUK A;  4P9V A;  2CS0 A;  2CBL A;  1AOU F;  1O42 A;  1O4F A;  1K9A A;  5EHP A;  4P9Z A;  1O4I A;  1O4P A;  1BKM A;  2CR4 A;  1F1W A;  2YSX A;  1MW4 A;  4JE4 A;  4F5A A;  1YVH A;  4JEG A;  2PTK A;  3TKZ A;  2OQ1 A;  1O4H A;  3GXX A;  1NRV A;  2L4K A;  5IBS A;  4NWF A;  4OHH A;  1NZL A;  2PNA A;  1AYC A;  1JYQ A;  1O4O A;  1O4R A;  2OZO A;  1BFI A;  4LUE A;  2SRC A;  2C0T A;  1Y1U A;  2MRK A;  2C0O A;  3T04 A;  1GRI A;  2FO0 A;  1BMB A;  5HKW A;  1GHU A;  4GL9 E;  4ROJ A;  2YU7 A;  3PJP A;  1BHH B;  2CI9 A;  4XZ1 A;  1IS0 A;  1BG1 A;  3QWY A;  5IBM A;  1RQQ C;  1RJA A;  1O43 A;  2IZV A;  5DC4 A;  5GJH A;  2AOA A;  3VS0 A;  1G83 A;  2XP1 A;  1O4E A;  1SHA A;  2Y1M A;  1JWO A;  3CD3 A;  1O4N A;  5EEQ A;  1KA6 A;  1HCS B;  2H8H A;  3BUN B;  5BO4 A;  3BKB A;  3S8N A;  1FU5 A;  1O41 A;  5D0J A;  1FMK A;  1XA6 A;  1O49 A;  4K44 A;  2Y3A B;  1JU5 A;  3PFV A;  1O48 A;  1AB2 A;  1X0N A;  2KNO A;  1IJR A;  3MXC A;  1D4W A;  2PNB A;  1QG1 E;  1X27 A;  1O44 A;  1Y57 A;  2RSY A;  3VRY A;  2LQN A;  5KAZ A;  1A09 A;  2PLE A;  1NZV A;  2EYV A;  2C0I A;  4E93 A;  1LKL A;  2PLD A;  4DGP A;  2MC1 A;  3WA4 A;  1UUR A;  3S9K A;  2IUH A;  3US4 A;  1BLJ A;  1ZFP E;  1M61 A;  3UYO A;  3IN8 A;  3VRN A;  1O4K A;  3N8M A;  3CWG A;  3EAC A;  3VRP A;  5EG3 B;  3PSJ A;  3BUO B;  4EIH A;  2DVJ A;  2HCK A;  4K45 A;  4XZ0 A;  1AYB A;  1CSY A;  2QMS A;  1M27 A;  4DGX A;  3M7F A;  1AYD A;  4H1O A;  3HHM B;  1A1B A;  3OB2 B;  1OO4 A;  4F5B A;  3OP0 A;  1OPK A;  1RPY A;  2L3T A;  2C9W A;  1LCK A;  3VS7 A;  2DLY A;  4FL2 A;  2MK2 A;  1QCF A;  2L6K A;  2EYZ A;  4FL3 A;  2MRJ A;  3N7Y A;  5AUL A;  4U1P A;  4D8K A;  4A4C A;  1R1P A;  2ABL A;  1OPL A;  2JYQ A;  2SHP A;  1Z3K A;  1I3Z A;  3VRR A;  4FBN A;  1LKK A;  3S8L A;  1LUM A;  2EL8 A;  1AYA A;  1FBV A;  2AOB A;  2K79 B;  4X6S A;  4OHE A;  2DCR A;  3BUW B;  3HCK A;  1O4C A;  4JGH A;  5CDW A;  2ETZ A;  3OVE A;  2H46 E;  3IMD A;  1QAD A;  1A81 A;  1O46 A;  2GSB A;  1BF5 A;  5GJI A;  2LNW A;  1A1E A;  3MAZ A;  1LUI A;  1KC2 A;  2K7A B;  2HMH A;  4LUD A;  2EYY A;  5I6V A;  1FHS A;  4OHL A;  1TZE E;  1BM2 A;  1SKJ A;  5HKZ A;  5J3X A;  2HDV A;  1BFJ A;  3CBL A;  1CWD L;  1LUN A;  3VS2 A;  4M4Z A;  2GE9 A;  5EHR A;  4L1B B;  1CJ1 A;  4K2R A;  4GWF A;  2RVF A;  3PLF B;  1D4T A;  1HCT B;  3QWX X;  4WWQ A;  1O4D A;  1CSZ A;  1WQU A;  1LCJ A;  4F59 A;  1H9O A;  3UF4 A;  3VS3 A;  3S8O A;  1O45 A;  2ROR A;  2FCI A;  2BBU A;  1B47 A;  2HUW A;  1SHD A;  1A1C A;  4QSY A;  2EOB A;  2LQW A;  1OO3 A;  1SPR A;  2CRH A;  3VGO A;  2DLZ A;  4K11 A;  4E68 A;  5DC0 B;  3EAZ A;  3VRO A;  2Y1N A;  1UUS A;  4H34 A;  2AUG A;  1O4G A;  1F2F A;  2CIA A;  1FYR A;  3PS5 A;  1O4M A;  3MXY A;  1R1Q A;  3BUM B;  3NHN A;  3IMJ A;  4NWG A;  1YVL A;  3HIZ B;  1FBZ A;  1O4J A;  3KFJ A;  2HDX A;  1KSW A;  1O4A A;  1A08 A;  4GPL B;  4U17 A;  3TL0 A;  3K2M A;  2KK6 A;  4OHI A;  3VS4 A;  2DX0 A;  2LNX A;  1AD5 A;  2IUI A;  4TZI A;  1BKL A;  5DC9 A;  2VIF A;  1X6C A;  3ZNI A;  2CI8 A;  3OB1 B;  1D1Z A;  1JYU A;  2B3O A;  1O47 A;  1A1A A;  1JYR A;  2DM0 A;  3OV1 A;  3CXL A;  5DF6 A;  3PSK A;  2LCT A;  2H5K A;  5EEL A;  5AXI A;  1BHF A;  1MIL A;  1R1S A;  2EO3 A;  1P13 A;  2EO6 A;  1O4Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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