3IMJA

Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-ptyr-ile-asn-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
101
structure length
101
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 101
sequence length 101
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3imjA00
4ROJA 3S8NA 4K45A 2EKXA 3MXCA 3VGOA 1SKJA 1BHHB 2RMXA 3QWYA 2DVJA 3VRNA 3S8LA 1JWOA 2HUWA 2OZOA 4JEGA 2PLEA 1O4BA 1O4GA 5EELA 4OHEA 2RVFA 4F5AA 2CI9A 1FU6A 1BM2A 1LUMA 3CD3A 4X6SA 3PSJA 1CSZA 2BBUA 4NWGA 1BHHA 2HDXA 1OPKA 1OO4A 3IMJA 1M27A 5HKZA 2LNWA 2LNXA 3VS7A 3S8OA 4LUEA 1MILA 3VROA 2RSYA 3T04A 3CWGA 1QG1E 2RORA 2AUGA 4TZIA 1RJAA 5BO4A 2HDVA 2EYYA 1UURA 1LKLA 1BHFA 2C0IA 1FBZA 2L4KA 1NRVA 5DC9A 1O4CA 2EYZA 1O4DA 1SPSA 1XA6A 1SPRA 2EYVA 1A1BA 1BMBA 1CJ1A 5HKWA 3GQIB 3C7IA 4EY0A 1QADA 2MRJA 3VRQA 1TCEA 4OHLA 1QCFA 1LKKA 2QMSA 1O4FA 2EL8A 1A07A 3OVEA 3QWXX 1BKLA 3IN8A 1O49A 1KSWA 4DGPA 3K2MA 1IJRA 3ZNIA 2C0TA 4P9ZA 1K9AA 3BUWB 1O4NA 3N84A 1O46A 3GXXA 1KA6A 4NWFA 1AYBA 5DC0B 1NZLA 4L1BB 3OP0A 3IMDA 2PNAA 4F59A 1O4IA 1JYRA 4LUDA 1O44A 1O42A 1RPYA 5GJHA 1H9OA 2LQNA 4A4CA 1BLJA 1LCJA 4P9VA 3TKZA 1X27A 1O4MA 3OV1A 4XZ1A 1GHUA 2H8HA 1A09A 1LUNA 1FBVA 1SHBA 1X6CA 2H5KA 2CS0A 4FL2A 3KFJA 4JE4A 4DGXA 4OHHA 2K7AB 4M4ZA 1MW4A 5IBMA 2IZVA 4E68A 1A1CA 2MRKA 1O4RA 2CR4A 5EHPA 1HCTB 1AD5A 3BUNB 3NHNA 2IUHA 2KNOA 1D4TA 2B3OA 2L6KA 1R1SA 2FCIA 1AB2A 1BLKA 4K11A 2SHPA 2EO6A 2ETZA 3N8MA 1O4QA 1AYCA 1O43A 3BUXB 2CBLA 4EIHA 3BUOB 1F2FA 1LUKA 3BUMB 5HKYA 1AYAA 3N7YA 1FYRA 4FBNA 1Y1UA 4GPLB 5I6VA 3BKBA 2SRCA 1A1AA 2ABLA 4GWFA 3VRZA 1O4KA 4OHDA 2DM0A 5DC4A 1A81A 2YU7A 2Y1NA 1YVHA 4U17A 1UUSA 3M7FA 1BG1A 1P13A 4FL3A 2KK6A 1KA7A 1ZFPE 2GSBA 1WQUA 4A4BA 3VS6A 4U1PA 3VS3A 3WA4A 3VRPA 1CWEA 2DX0A 2LQWA 1O4OA 4H1OA 5DF6A 1SHDA 5EEQA 1O45A 2AOBA 5J3XA 4WWQA 4K2RA 1PICA 1JYQA 1OO3A 1O4EA 3PSKA 4H34A 1O48A 1B47A 2CI8A 1LUIA 3S9KA 1AOTF 2H46E 5CDWA 3PLFB 1A1EA 3HIZB 2EO3A 4GL9E 1X0NA 2EOBA 4E93A 1LCKA 2HCKA 4QSYA 1AOUF 3CBLA 2CIAA 2ECDA 1O4AA 1OPLA 4JGHA 2Y3AB 5GJIA 1JU5A 5IBSA 5EG3B 1BKMA 1O4PA 1BFJA 2MQIA 1FU5A 1O4LA 2IUGA 3GXWA 3VS5A 3VS1A 2HMHA 1TZEE 3HHMB 3US4A 4OHIA 1F1WA 3PFVA 2FO0A 3UF4A 3EACA 2PLDA 2PTKA 2C9WA 2DLYA 1O4JA 1AYDA 3PQZA 1A08A 2AOAA 2EU0A 3VS2A 1HCSB 1D4WA 5AXIA 3VS0A 1O4HA 1FHSA 1RQQC 4D8KA 2DCRA 1CSYA 1R1PA 1O47A 3OB1B 1IS0A 1R1QA 4K44A 1FMKA 4F5BA 1G83A 1BFIA 3VRYA 1GRIA 2OQ1A 2LCTA 2YSXA 3IN7A 1D1ZA 2Y1MA 5KAZA 2CRHA 2C0OA 3EAZA 3UYOA 3VS4A 3CXLA 3TL0A 2DLZA 1KC2A 2GE9A 3PS5A 1I3ZA 3PJPA 1CWDL 1BF5A 5D0JA 2VIFA 5AULA 1JYUA 2PNBA 2MC1A 5EHRA 2K79B 1YVLA 3VRRA 1O41A 2L3TA 3OB2B 1Y57A 1NZVA 2IUIA 2XP1A 3HCKA 1Z3KA 1M61A 1SHAA 2JYQA 4XZ0A 3MXYA 2MK2A 3MAZA
chains in the Genus database with same CATH superfamily
4ROJA 3S8NA 4K45A 2EKXA 3MXCA 3VGOA 1SKJA 1BHHB 2RMXA 3QWYA 2DVJA 3VRNA 3S8LA 1JWOA 2HUWA 2OZOA 4JEGA 2PLEA 1O4BA 1O4GA 5EELA 4OHEA 2RVFA 4F5AA 2CI9A 1FU6A 1BM2A 1LUMA 3CD3A 4X6SA 3PSJA 1CSZA 2BBUA 4NWGA 1BHHA 2HDXA 1OPKA 1OO4A 3IMJA 1M27A 5HKZA 2LNWA 2LNXA 3VS7A 3S8OA 4LUEA 1MILA 3VROA 2RSYA 3T04A 3CWGA 1QG1E 2RORA 2AUGA 4TZIA 1RJAA 5BO4A 2HDVA 2EYYA 1UURA 1LKLA 1BHFA 2C0IA 1FBZA 2L4KA 1NRVA 5DC9A 1O4CA 2EYZA 1O4DA 1SPSA 1XA6A 1SPRA 2EYVA 1A1BA 1BMBA 1CJ1A 5HKWA 3GQIB 3C7IA 4EY0A 1QADA 2MRJA 3VRQA 1TCEA 4OHLA 1QCFA 1LKKA 2QMSA 1O4FA 2EL8A 1A07A 3OVEA 3QWXX 1BKLA 3IN8A 1O49A 1KSWA 4DGPA 3K2MA 3K2TA 1IJRA 3ZNIA 2C0TA 4P9ZA 1K9AA 3BUWB 1O4NA 3N84A 1O46A 3GXXA 1KA6A 4NWFA 1AYBA 5DC0B 1NZLA 4L1BB 3OP0A 3IMDA 2PNAA 4F59A 1O4IA 1JYRA 4LUDA 1O44A 1O42A 1RPYA 5GJHA 1H9OA 2LQNA 4A4CA 1BLJA 1LCJA 4P9VA 3TKZA 1X27A 1O4MA 3OV1A 4XZ1A 1GHUA 2H8HA 1A09A 1LUNA 1FBVA 1SHBA 1X6CA 2H5KA 2CS0A 4FL2A 3KFJA 4JE4A 4DGXA 4OHHA 2K7AB 4M4ZA 1MW4A 5IBMA 2IZVA 4E68A 1A1CA 2MRKA 1O4RA 2CR4A 5EHPA 1HCTB 1AD5A 3BUNB 3NHNA 2IUHA 2KNOA 1D4TA 2B3OA 2L6KA 1R1SA 2FCIA 1AB2A 1BLKA 4K11A 2SHPA 2EO6A 2ETZA 3N8MA 1O4QA 1AYCA 1O43A 3BUXB 2CBLA 4EIHA 3BUOB 1F2FA 1LUKA 3BUMB 5HKYA 1AYAA 3N7YA 1FYRA 4FBNA 1Y1UA 4GPLB 5I6VA 3BKBA 2SRCA 1A1AA 2ABLA 4GWFA 3VRZA 1O4KA 4OHDA 2DM0A 5DC4A 1A81A 2YU7A 2Y1NA 1YVHA 4U17A 1UUSA 3M7FA 1BG1A 1P13A 4FL3A 2KK6A 1KA7A 1ZFPE 2GSBA 1WQUA 4A4BA 3VS6A 4U1PA 3VS3A 3WA4A 2KGYA 3VRPA 1CWEA 2DX0A 2LQWA 1O4OA 4H1OA 5DF6A 1SHDA 5EEQA 1O45A 2AOBA 2LRAA 5J3XA 4WWQA 4K2RA 1PICA 1JYQA 1OO3A 1O4EA 3PSKA 4H34A 1O48A 1B47A 2CI8A 1LUIA 3S9KA 1AOTF 2H46E 5CDWA 3PLFB 1A1EA 3HIZB 2EO3A 4GL9E 1X0NA 2EOBA 4E93A 1LCKA 2HCKA 4QSYA 1AOUF 3CBLA 2CIAA 2ECDA 3LYVA 1O4AA 1OPLA 4JGHA 2Y3AB 5GJIA 1JU5A 5IBSA 5EG3B 1BKMA 1O4PA 1BFJA 2MQIA 1FU5A 1O4LA 2IUGA 3GXWA 3VS5A 3VS1A 2HMHA 1TZEE 3HHMB 3US4A 4OHIA 1F1WA 3PFVA 2FO0A 3UF4A 3EACA 2PLDA 2PTKA 2C9WA 2DLYA 1O4JA 1AYDA 3PQZA 1A08A 2AOAA 2EU0A 3VS2A 1HCSB 1D4WA 5AXIA 3VS0A 1O4HA 1FHSA 1RQQC 4D8KA 2DCRA 1CSYA 1R1PA 1O47A 3OB1B 1IS0A 1R1QA 4K44A 1FMKA 4F5BA 1G83A 1BFIA 3VRYA 1GRIA 2OQ1A 2LCTA 2YSXA 3IN7A 1D1ZA 2Y1MA 5KAZA 2CRHA 2C0OA 3EAZA 3UYOA 3VS4A 3CXLA 3TL0A 2DLZA 1KC2A 2GE9A 3PS5A 1I3ZA 3PJPA 1CWDL 1BF5A 5D0JA 2VIFA 5AULA 1JYUA 2PNBA 2MC1A 5EHRA 2K79B 1YVLA 3VRRA 1O41A 2L3TA 3OB2B 1Y57A 1NZVA 2IUIA 2XP1A 3HCKA 1Z3KA 1M61A 1SHAA 2JYQA 4XZ0A 3MXYA 2MK2A 3MAZA
chains in the Genus database with same CATH topology
4ROJA 3S8NA 4K45A 2EKXA 3MXCA 3VGOA 1SKJA 1BHHB 2RMXA 3QWYA 2DVJA 3VRNA 3S8LA 1JWOA 2HUWA 2OZOA 4JEGA 2PLEA 1O4BA 1O4GA 5EELA 4OHEA 2RVFA 4F5AA 2CI9A 1FU6A 1BM2A 1LUMA 3CD3A 4X6SA 3PSJA 1CSZA 2BBUA 4NWGA 1BHHA 2HDXA 1OPKA 1OO4A 3IMJA 1M27A 5HKZA 2LNWA 2LNXA 3VS7A 3S8OA 4LUEA 1MILA 3VROA 2RSYA 3T04A 3CWGA 1QG1E 2RORA 2AUGA 4TZIA 1RJAA 5BO4A 2HDVA 2EYYA 1UURA 1LKLA 1BHFA 2C0IA 1FBZA 2L4KA 1NRVA 5DC9A 1O4CA 2EYZA 1O4DA 1SPSA 1XA6A 1SPRA 2EYVA 1A1BA 1BMBA 1CJ1A 5HKWA 3GQIB 3C7IA 4EY0A 1QADA 2MRJA 3VRQA 1TCEA 4OHLA 1QCFA 1LKKA 2QMSA 1O4FA 2EL8A 1A07A 3OVEA 3QWXX 1BKLA 3IN8A 1O49A 1KSWA 4DGPA 3K2MA 1IJRA 3ZNIA 2C0TA 4P9ZA 1K9AA 3BUWB 1O4NA 3N84A 1O46A 3GXXA 1KA6A 4NWFA 1AYBA 5DC0B 1NZLA 4L1BB 3OP0A 3IMDA 2PNAA 4F59A 1O4IA 1JYRA 4LUDA 1O44A 1O42A 1RPYA 5GJHA 1H9OA 2LQNA 4A4CA 1BLJA 1LCJA 4P9VA 3TKZA 1X27A 1O4MA 3OV1A 4XZ1A 1GHUA 2H8HA 1A09A 1LUNA 1FBVA 1SHBA 1X6CA 2H5KA 2CS0A 4FL2A 3KFJA 4JE4A 4DGXA 4OHHA 2K7AB 4M4ZA 1MW4A 5IBMA 2IZVA 4E68A 1A1CA 2MRKA 1O4RA 2CR4A 5EHPA 1HCTB 1AD5A 3BUNB 3NHNA 2IUHA 2KNOA 1D4TA 2B3OA 2L6KA 1R1SA 2FCIA 1AB2A 1BLKA 4K11A 2SHPA 2EO6A 2ETZA 3N8MA 1O4QA 1AYCA 1O43A 3BUXB 2CBLA 4EIHA 3BUOB 1F2FA 1LUKA 3BUMB 5HKYA 1AYAA 3N7YA 1FYRA 4FBNA 1Y1UA 4GPLB 5I6VA 3BKBA 2SRCA 1A1AA 2ABLA 4GWFA 3VRZA 1O4KA 4OHDA 2DM0A 5DC4A 1A81A 2YU7A 2Y1NA 1YVHA 4U17A 1UUSA 3M7FA 1BG1A 1P13A 4FL3A 2KK6A 1KA7A 1ZFPE 2GSBA 1WQUA 4A4BA 3VS6A 4U1PA 3VS3A 3WA4A 3VRPA 1CWEA 2DX0A 2LQWA 1O4OA 4H1OA 5DF6A 1SHDA 5EEQA 1O45A 2AOBA 5J3XA 4WWQA 4K2RA 1PICA 1JYQA 1OO3A 1O4EA 3PSKA 4H34A 1O48A 1B47A 2CI8A 1LUIA 3S9KA 1AOTF 2H46E 5CDWA 3PLFB 1A1EA 3HIZB 2EO3A 4GL9E 1X0NA 2EOBA 4E93A 1LCKA 2HCKA 4QSYA 1AOUF 3CBLA 2CIAA 2ECDA 1O4AA 1OPLA 4JGHA 2Y3AB 5GJIA 1JU5A 5IBSA 5EG3B 1BKMA 1O4PA 1BFJA 2MQIA 1FU5A 1O4LA 2IUGA 3GXWA 3VS5A 3VS1A 2HMHA 1TZEE 3HHMB 3US4A 4OHIA 1F1WA 3PFVA 2FO0A 3UF4A 3EACA 2PLDA 2PTKA 2C9WA 2DLYA 1O4JA 1AYDA 3PQZA 1A08A 2AOAA 2EU0A 3VS2A 1HCSB 1D4WA 5AXIA 3VS0A 1O4HA 1FHSA 1RQQC 4D8KA 2DCRA 1CSYA 1R1PA 1O47A 3OB1B 1IS0A 1R1QA 4K44A 1FMKA 4F5BA 1G83A 1BFIA 3VRYA 1GRIA 2OQ1A 2LCTA 2YSXA 3IN7A 1D1ZA 2Y1MA 5KAZA 2CRHA 2C0OA 3EAZA 3UYOA 3VS4A 3CXLA 3TL0A 2DLZA 1KC2A 2GE9A 3PS5A 1I3ZA 3PJPA 1CWDL 1BF5A 5D0JA 2VIFA 5AULA 1JYUA 2PNBA 2MC1A 5EHRA 2K79B 1YVLA 3VRRA 1O41A 2L3TA 3OB2B 1Y57A 1NZVA 2IUIA 2XP1A 3HCKA 1Z3KA 1M61A 1SHAA 2JYQA 4XZ0A 3MXYA 2MK2A 3MAZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ROJ A;  3S8N A;  4K45 A;  2EKX A;  3MXC A;  3VGO A;  1SKJ A;  1BHH B;  2RMX A;  3QWY A;  2DVJ A;  3VRN A;  3S8L A;  1JWO A;  2HUW A;  2OZO A;  4JEG A;  2PLE A;  1O4B A;  1O4G A;  5EEL A;  4OHE A;  2RVF A;  4F5A A;  2CI9 A;  1FU6 A;  1BM2 A;  1LUM A;  3CD3 A;  4X6S A;  3PSJ A;  1CSZ A;  2BBU A;  4NWG A;  1BHH A;  2HDX A;  1OPK A;  1OO4 A;  3IMJ A;  1M27 A;  5HKZ A;  2LNW A;  2LNX A;  3VS7 A;  3S8O A;  4LUE A;  1MIL A;  3VRO A;  2RSY A;  3T04 A;  3CWG A;  1QG1 E;  2ROR A;  2AUG A;  4TZI A;  1RJA A;  5BO4 A;  2HDV A;  2EYY A;  1UUR A;  1LKL A;  1BHF A;  2C0I A;  1FBZ A;  2L4K A;  1NRV A;  5DC9 A;  1O4C A;  2EYZ A;  1O4D A;  1SPS A;  1XA6 A;  1SPR A;  2EYV A;  1A1B A;  1BMB A;  1CJ1 A;  5HKW A;  3GQI B;  3C7I A;  4EY0 A;  1QAD A;  2MRJ A;  3VRQ A;  1TCE A;  4OHL A;  1QCF A;  1LKK A;  2QMS A;  1O4F A;  2EL8 A;  1A07 A;  3OVE A;  3QWX X;  1BKL A;  3IN8 A;  1O49 A;  1KSW A;  4DGP A;  3K2M A;  1IJR A;  3ZNI A;  2C0T A;  4P9Z A;  1K9A A;  3BUW B;  1O4N A;  3N84 A;  1O46 A;  3GXX A;  1KA6 A;  4NWF A;  1AYB A;  5DC0 B;  1NZL A;  4L1B B;  3OP0 A;  3IMD A;  2PNA A;  4F59 A;  1O4I A;  1JYR A;  4LUD A;  1O44 A;  1O42 A;  1RPY A;  5GJH A;  1H9O A;  2LQN A;  4A4C A;  1BLJ A;  1LCJ A;  4P9V A;  3TKZ A;  1X27 A;  1O4M A;  3OV1 A;  4XZ1 A;  1GHU A;  2H8H A;  1A09 A;  1LUN A;  1FBV A;  1SHB A;  1X6C A;  2H5K A;  2CS0 A;  4FL2 A;  3KFJ A;  4JE4 A;  4DGX A;  4OHH A;  2K7A B;  4M4Z A;  1MW4 A;  5IBM A;  2IZV A;  4E68 A;  1A1C A;  2MRK A;  1O4R A;  2CR4 A;  5EHP A;  1HCT B;  1AD5 A;  3BUN B;  3NHN A;  2IUH A;  2KNO A;  1D4T A;  2B3O A;  2L6K A;  1R1S A;  2FCI A;  1AB2 A;  1BLK A;  4K11 A;  2SHP A;  2EO6 A;  2ETZ A;  3N8M A;  1O4Q A;  1AYC A;  1O43 A;  3BUX B;  2CBL A;  4EIH A;  3BUO B;  1F2F A;  1LUK A;  3BUM B;  5HKY A;  1AYA A;  3N7Y A;  1FYR A;  4FBN A;  1Y1U A;  4GPL B;  5I6V A;  3BKB A;  2SRC A;  1A1A A;  2ABL A;  4GWF A;  3VRZ A;  1O4K A;  4OHD A;  2DM0 A;  5DC4 A;  1A81 A;  2YU7 A;  2Y1N A;  1YVH A;  4U17 A;  1UUS A;  3M7F A;  1BG1 A;  1P13 A;  4FL3 A;  2KK6 A;  1KA7 A;  1ZFP E;  2GSB A;  1WQU A;  4A4B A;  3VS6 A;  4U1P A;  3VS3 A;  3WA4 A;  3VRP A;  1CWE A;  2DX0 A;  2LQW A;  1O4O A;  4H1O A;  5DF6 A;  1SHD A;  5EEQ A;  1O45 A;  2AOB A;  5J3X A;  4WWQ A;  4K2R A;  1PIC A;  1JYQ A;  1OO3 A;  1O4E A;  3PSK A;  4H34 A;  1O48 A;  1B47 A;  2CI8 A;  1LUI A;  3S9K A;  1AOT F;  2H46 E;  5CDW A;  3PLF B;  1A1E A;  3HIZ B;  2EO3 A;  4GL9 E;  1X0N A;  2EOB A;  4E93 A;  1LCK A;  2HCK A;  4QSY A;  1AOU F;  3CBL A;  2CIA A;  2ECD A;  1O4A A;  1OPL A;  4JGH A;  2Y3A B;  5GJI A;  1JU5 A;  5IBS A;  5EG3 B;  1BKM A;  1O4P A;  1BFJ A;  2MQI A;  1FU5 A;  1O4L A;  2IUG A;  3GXW A;  3VS5 A;  3VS1 A;  2HMH A;  1TZE E;  3HHM B;  3US4 A;  4OHI A;  1F1W A;  3PFV A;  2FO0 A;  3UF4 A;  3EAC A;  2PLD A;  2PTK A;  2C9W A;  2DLY A;  1O4J A;  1AYD A;  3PQZ A;  1A08 A;  2AOA A;  2EU0 A;  3VS2 A;  1HCS B;  1D4W A;  5AXI A;  3VS0 A;  1O4H A;  1FHS A;  1RQQ C;  4D8K A;  2DCR A;  1CSY A;  1R1P A;  1O47 A;  3OB1 B;  1IS0 A;  1R1Q A;  4K44 A;  1FMK A;  4F5B A;  1G83 A;  1BFI A;  3VRY A;  1GRI A;  2OQ1 A;  2LCT A;  2YSX A;  3IN7 A;  1D1Z A;  2Y1M A;  5KAZ A;  2CRH A;  2C0O A;  3EAZ A;  3UYO A;  3VS4 A;  3CXL A;  3TL0 A;  2DLZ A;  1KC2 A;  2GE9 A;  3PS5 A;  1I3Z A;  3PJP A;  1CWD L;  1BF5 A;  5D0J A;  2VIF A;  5AUL A;  1JYU A;  2PNB A;  2MC1 A;  5EHR A;  2K79 B;  1YVL A;  3VRR A;  1O41 A;  2L3T A;  3OB2 B;  1Y57 A;  1NZV A;  2IUI A;  2XP1 A;  3HCK A;  1Z3K A;  1M61 A;  1SHA A;  2JYQ A;  4XZ0 A;  3MXY A;  2MK2 A;  3MAZ A; 
#chains in the Genus database with same CATH topology
 4ROJ A;  3S8N A;  4K45 A;  2EKX A;  3MXC A;  3VGO A;  1SKJ A;  1BHH B;  2RMX A;  3QWY A;  2DVJ A;  3VRN A;  3S8L A;  1JWO A;  2HUW A;  2OZO A;  4JEG A;  2PLE A;  1O4B A;  1O4G A;  5EEL A;  4OHE A;  2RVF A;  4F5A A;  2CI9 A;  1FU6 A;  1BM2 A;  1LUM A;  3CD3 A;  4X6S A;  3PSJ A;  1CSZ A;  2BBU A;  4NWG A;  1BHH A;  2HDX A;  1OPK A;  1OO4 A;  3IMJ A;  1M27 A;  5HKZ A;  2LNW A;  2LNX A;  3VS7 A;  3S8O A;  4LUE A;  1MIL A;  3VRO A;  2RSY A;  3T04 A;  3CWG A;  1QG1 E;  2ROR A;  2AUG A;  4TZI A;  1RJA A;  5BO4 A;  2HDV A;  2EYY A;  1UUR A;  1LKL A;  1BHF A;  2C0I A;  1FBZ A;  2L4K A;  1NRV A;  5DC9 A;  1O4C A;  2EYZ A;  1O4D A;  1SPS A;  1XA6 A;  1SPR A;  2EYV A;  1A1B A;  1BMB A;  1CJ1 A;  5HKW A;  3GQI B;  3C7I A;  4EY0 A;  1QAD A;  2MRJ A;  3VRQ A;  1TCE A;  4OHL A;  1QCF A;  1LKK A;  2QMS A;  1O4F A;  2EL8 A;  1A07 A;  3OVE A;  3QWX X;  1BKL A;  3IN8 A;  1O49 A;  1KSW A;  4DGP A;  3K2M A;  3K2T A;  1IJR A;  3ZNI A;  2C0T A;  4P9Z A;  1K9A A;  3BUW B;  1O4N A;  3N84 A;  1O46 A;  3GXX A;  1KA6 A;  4NWF A;  1AYB A;  5DC0 B;  1NZL A;  4L1B B;  3OP0 A;  3IMD A;  2PNA A;  4F59 A;  1O4I A;  1JYR A;  4LUD A;  1O44 A;  1O42 A;  1RPY A;  5GJH A;  1H9O A;  2LQN A;  4A4C A;  1BLJ A;  1LCJ A;  4P9V A;  3TKZ A;  1X27 A;  1O4M A;  3OV1 A;  4XZ1 A;  1GHU A;  2H8H A;  1A09 A;  1LUN A;  1FBV A;  1SHB A;  1X6C A;  2H5K A;  2CS0 A;  4FL2 A;  3KFJ A;  4JE4 A;  4DGX A;  4OHH A;  2K7A B;  4M4Z A;  1MW4 A;  5IBM A;  2IZV A;  4E68 A;  1A1C A;  2MRK A;  1O4R A;  2CR4 A;  5EHP A;  1HCT B;  1AD5 A;  3BUN B;  3NHN A;  2IUH A;  2KNO A;  1D4T A;  2B3O A;  2L6K A;  1R1S A;  2FCI A;  1AB2 A;  1BLK A;  4K11 A;  2SHP A;  2EO6 A;  2ETZ A;  3N8M A;  1O4Q A;  1AYC A;  1O43 A;  3BUX B;  2CBL A;  4EIH A;  3BUO B;  1F2F A;  1LUK A;  3BUM B;  5HKY A;  1AYA A;  3N7Y A;  1FYR A;  4FBN A;  1Y1U A;  4GPL B;  5I6V A;  3BKB A;  2SRC A;  1A1A A;  2ABL A;  4GWF A;  3VRZ A;  1O4K A;  4OHD A;  2DM0 A;  5DC4 A;  1A81 A;  2YU7 A;  2Y1N A;  1YVH A;  4U17 A;  1UUS A;  3M7F A;  1BG1 A;  1P13 A;  4FL3 A;  2KK6 A;  1KA7 A;  1ZFP E;  2GSB A;  1WQU A;  4A4B A;  3VS6 A;  4U1P A;  3VS3 A;  3WA4 A;  2KGY A;  3VRP A;  1CWE A;  2DX0 A;  2LQW A;  1O4O A;  4H1O A;  5DF6 A;  1SHD A;  5EEQ A;  1O45 A;  2AOB A;  2LRA A;  5J3X A;  4WWQ A;  4K2R A;  1PIC A;  1JYQ A;  1OO3 A;  1O4E A;  3PSK A;  4H34 A;  1O48 A;  1B47 A;  2CI8 A;  1LUI A;  3S9K A;  1AOT F;  2H46 E;  5CDW A;  3PLF B;  1A1E A;  3HIZ B;  2EO3 A;  4GL9 E;  1X0N A;  2EOB A;  4E93 A;  1LCK A;  2HCK A;  4QSY A;  1AOU F;  3CBL A;  2CIA A;  2ECD A;  3LYV A;  1O4A A;  1OPL A;  4JGH A;  2Y3A B;  5GJI A;  1JU5 A;  5IBS A;  5EG3 B;  1BKM A;  1O4P A;  1BFJ A;  2MQI A;  1FU5 A;  1O4L A;  2IUG A;  3GXW A;  3VS5 A;  3VS1 A;  2HMH A;  1TZE E;  3HHM B;  3US4 A;  4OHI A;  1F1W A;  3PFV A;  2FO0 A;  3UF4 A;  3EAC A;  2PLD A;  2PTK A;  2C9W A;  2DLY A;  1O4J A;  1AYD A;  3PQZ A;  1A08 A;  2AOA A;  2EU0 A;  3VS2 A;  1HCS B;  1D4W A;  5AXI A;  3VS0 A;  1O4H A;  1FHS A;  1RQQ C;  4D8K A;  2DCR A;  1CSY A;  1R1P A;  1O47 A;  3OB1 B;  1IS0 A;  1R1Q A;  4K44 A;  1FMK A;  4F5B A;  1G83 A;  1BFI A;  3VRY A;  1GRI A;  2OQ1 A;  2LCT A;  2YSX A;  3IN7 A;  1D1Z A;  2Y1M A;  5KAZ A;  2CRH A;  2C0O A;  3EAZ A;  3UYO A;  3VS4 A;  3CXL A;  3TL0 A;  2DLZ A;  1KC2 A;  2GE9 A;  3PS5 A;  1I3Z A;  3PJP A;  1CWD L;  1BF5 A;  5D0J A;  2VIF A;  5AUL A;  1JYU A;  2PNB A;  2MC1 A;  5EHR A;  2K79 B;  1YVL A;  3VRR A;  1O41 A;  2L3T A;  3OB2 B;  1Y57 A;  1NZV A;  2IUI A;  2XP1 A;  3HCK A;  1Z3K A;  1M61 A;  1SHA A;  2JYQ A;  4XZ0 A;  3MXY A;  2MK2 A;  3MAZ A; 
#chains in the Genus database with same CATH homology
 4ROJ A;  3S8N A;  4K45 A;  2EKX A;  3MXC A;  3VGO A;  1SKJ A;  1BHH B;  2RMX A;  3QWY A;  2DVJ A;  3VRN A;  3S8L A;  1JWO A;  2HUW A;  2OZO A;  4JEG A;  2PLE A;  1O4B A;  1O4G A;  5EEL A;  4OHE A;  2RVF A;  4F5A A;  2CI9 A;  1FU6 A;  1BM2 A;  1LUM A;  3CD3 A;  4X6S A;  3PSJ A;  1CSZ A;  2BBU A;  4NWG A;  1BHH A;  2HDX A;  1OPK A;  1OO4 A;  3IMJ A;  1M27 A;  5HKZ A;  2LNW A;  2LNX A;  3VS7 A;  3S8O A;  4LUE A;  1MIL A;  3VRO A;  2RSY A;  3T04 A;  3CWG A;  1QG1 E;  2ROR A;  2AUG A;  4TZI A;  1RJA A;  5BO4 A;  2HDV A;  2EYY A;  1UUR A;  1LKL A;  1BHF A;  2C0I A;  1FBZ A;  2L4K A;  1NRV A;  5DC9 A;  1O4C A;  2EYZ A;  1O4D A;  1SPS A;  1XA6 A;  1SPR A;  2EYV A;  1A1B A;  1BMB A;  1CJ1 A;  5HKW A;  3GQI B;  3C7I A;  4EY0 A;  1QAD A;  2MRJ A;  3VRQ A;  1TCE A;  4OHL A;  1QCF A;  1LKK A;  2QMS A;  1O4F A;  2EL8 A;  1A07 A;  3OVE A;  3QWX X;  1BKL A;  3IN8 A;  1O49 A;  1KSW A;  4DGP A;  3K2M A;  1IJR A;  3ZNI A;  2C0T A;  4P9Z A;  1K9A A;  3BUW B;  1O4N A;  3N84 A;  1O46 A;  3GXX A;  1KA6 A;  4NWF A;  1AYB A;  5DC0 B;  1NZL A;  4L1B B;  3OP0 A;  3IMD A;  2PNA A;  4F59 A;  1O4I A;  1JYR A;  4LUD A;  1O44 A;  1O42 A;  1RPY A;  5GJH A;  1H9O A;  2LQN A;  4A4C A;  1BLJ A;  1LCJ A;  4P9V A;  3TKZ A;  1X27 A;  1O4M A;  3OV1 A;  4XZ1 A;  1GHU A;  2H8H A;  1A09 A;  1LUN A;  1FBV A;  1SHB A;  1X6C A;  2H5K A;  2CS0 A;  4FL2 A;  3KFJ A;  4JE4 A;  4DGX A;  4OHH A;  2K7A B;  4M4Z A;  1MW4 A;  5IBM A;  2IZV A;  4E68 A;  1A1C A;  2MRK A;  1O4R A;  2CR4 A;  5EHP A;  1HCT B;  1AD5 A;  3BUN B;  3NHN A;  2IUH A;  2KNO A;  1D4T A;  2B3O A;  2L6K A;  1R1S A;  2FCI A;  1AB2 A;  1BLK A;  4K11 A;  2SHP A;  2EO6 A;  2ETZ A;  3N8M A;  1O4Q A;  1AYC A;  1O43 A;  3BUX B;  2CBL A;  4EIH A;  3BUO B;  1F2F A;  1LUK A;  3BUM B;  5HKY A;  1AYA A;  3N7Y A;  1FYR A;  4FBN A;  1Y1U A;  4GPL B;  5I6V A;  3BKB A;  2SRC A;  1A1A A;  2ABL A;  4GWF A;  3VRZ A;  1O4K A;  4OHD A;  2DM0 A;  5DC4 A;  1A81 A;  2YU7 A;  2Y1N A;  1YVH A;  4U17 A;  1UUS A;  3M7F A;  1BG1 A;  1P13 A;  4FL3 A;  2KK6 A;  1KA7 A;  1ZFP E;  2GSB A;  1WQU A;  4A4B A;  3VS6 A;  4U1P A;  3VS3 A;  3WA4 A;  3VRP A;  1CWE A;  2DX0 A;  2LQW A;  1O4O A;  4H1O A;  5DF6 A;  1SHD A;  5EEQ A;  1O45 A;  2AOB A;  5J3X A;  4WWQ A;  4K2R A;  1PIC A;  1JYQ A;  1OO3 A;  1O4E A;  3PSK A;  4H34 A;  1O48 A;  1B47 A;  2CI8 A;  1LUI A;  3S9K A;  1AOT F;  2H46 E;  5CDW A;  3PLF B;  1A1E A;  3HIZ B;  2EO3 A;  4GL9 E;  1X0N A;  2EOB A;  4E93 A;  1LCK A;  2HCK A;  4QSY A;  1AOU F;  3CBL A;  2CIA A;  2ECD A;  1O4A A;  1OPL A;  4JGH A;  2Y3A B;  5GJI A;  1JU5 A;  5IBS A;  5EG3 B;  1BKM A;  1O4P A;  1BFJ A;  2MQI A;  1FU5 A;  1O4L A;  2IUG A;  3GXW A;  3VS5 A;  3VS1 A;  2HMH A;  1TZE E;  3HHM B;  3US4 A;  4OHI A;  1F1W A;  3PFV A;  2FO0 A;  3UF4 A;  3EAC A;  2PLD A;  2PTK A;  2C9W A;  2DLY A;  1O4J A;  1AYD A;  3PQZ A;  1A08 A;  2AOA A;  2EU0 A;  3VS2 A;  1HCS B;  1D4W A;  5AXI A;  3VS0 A;  1O4H A;  1FHS A;  1RQQ C;  4D8K A;  2DCR A;  1CSY A;  1R1P A;  1O47 A;  3OB1 B;  1IS0 A;  1R1Q A;  4K44 A;  1FMK A;  4F5B A;  1G83 A;  1BFI A;  3VRY A;  1GRI A;  2OQ1 A;  2LCT A;  2YSX A;  3IN7 A;  1D1Z A;  2Y1M A;  5KAZ A;  2CRH A;  2C0O A;  3EAZ A;  3UYO A;  3VS4 A;  3CXL A;  3TL0 A;  2DLZ A;  1KC2 A;  2GE9 A;  3PS5 A;  1I3Z A;  3PJP A;  1CWD L;  1BF5 A;  5D0J A;  2VIF A;  5AUL A;  1JYU A;  2PNB A;  2MC1 A;  5EHR A;  2K79 B;  1YVL A;  3VRR A;  1O41 A;  2L3T A;  3OB2 B;  1Y57 A;  1NZV A;  2IUI A;  2XP1 A;  3HCK A;  1Z3K A;  1M61 A;  1SHA A;  2JYQ A;  4XZ0 A;  3MXY A;  2MK2 A;  3MAZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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