3IN7A

Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-py-q-n-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
99
structure length
99
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 99
sequence length 99
chains with identical sequence C
ec nomenclature
pdb deposition date 2009-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3in7A00
1JU5A 1LUKA 3VRNA 1AD5A 3MXCA 2AUGA 4H34A 1K9AA 3NHNA 1QADA 3C7IA 3PSJA 2AOBA 4JE4A 4OHHA 1O4IA 2EYYA 1O44A 3BUMB 2SHPA 5IBMA 1FMKA 1BHHA 1D1ZA 1A07A 2CR4A 3GQIB 4NWFA 4GL9E 4A4BA 3BUWB 2EU0A 1BHFA 1Y57A 2EO6A 3PFVA 2GSBA 3EACA 4DGXA 3VGOA 1F1WA 4M4ZA 4X6SA 1O4CA 3TKZA 2JYQA 1SPSA 5I6VA 3MXYA 1I3ZA 2LQNA 5CDWA 3OVEA 2KNOA 3TL0A 1QG1E 1BLJA 1KC2A 1CWEA 2HMHA 3CD3A 1BG1A 1M61A 3VS2A 1SKJA 4OHLA 1FBZA 2LQWA 1A08A 2LCTA 2DCRA 2MK2A 2L3TA 1O4BA 1RQQC 1KA6A 1WQUA 1AOTF 4OHEA 1P13A 4ROJA 4XZ1A 5DC0B 4JGHA 3VS7A 2RMXA 2K7AB 1O4MA 1AB2A 3K2MA 1KSWA 2GE9A 2OQ1A 1AYCA 4NWGA 4GPLB 3M7FA 1X0NA 2FCIA 2EKXA 1JYQA 2EL8A 4A4CA 3N7YA 1O48A 2CRHA 2OZOA 1O45A 3OP0A 2EOBA 3N84A 3VS1A 1AYDA 2ETZA 2KK6A 2XP1A 2CS0A 3IN8A 1KA7A 2MRJA 4D8KA 1NZVA 1M27A 3QWXX 5EG3B 4F5AA 1BKMA 1A1BA 3HCKA 1OPLA 3T04A 1Z3KA 1F2FA 1UURA 3N8MA 1GRIA 1BHHB 4K44A 2Y1MA 2CBLA 3QWYA 1FHSA 1O4AA 2QMSA 3OB2B 2EYVA 2EYZA 5EELA 3PLFB 3VS4A 5GJIA 4E68A 3VRQA 1CWDL 1FYRA 2RVFA 5EEQA 3BKBA 4OHDA 4JEGA 1BFJA 1SHBA 1UUSA 2L4KA 3IMDA 1MILA 3HHMB 1R1PA 1BM2A 3HIZB 1O42A 2DLZA 1D4WA 1O4QA 2Y1NA 1TCEA 1LCJA 1IJRA 1R1SA 1A1CA 2PNAA 2HUWA 2LNWA 4E93A 1GHUA 5EHPA 2H46E 3PSKA 3VRZA 4H1OA 3GXWA 1O4GA 2RSYA 2L6KA 3VROA 1JYUA 1O4KA 4FL3A 3VS3A 2CIAA 1CJ1A 2B3OA 3ZNIA 1G83A 4U1PA 1O4PA 2FO0A 2C0IA 2C0OA 1FU6A 1H9OA 1O4FA 2H8HA 5IBSA 4GWFA 1HCTB 4P9ZA 3KFJA 1OPKA 1LKKA 5D0JA 1A09A 1BFIA 2H5KA 1JWOA 3PJPA 3VS0A 2Y3AB 4F59A 3PQZA 1LCKA 3S8NA 2ECDA 1O49A 1CSYA 1RJAA 1A1EA 5HKYA 1TZEE 4K2RA 4F5BA 4DGPA 3OV1A 1LUIA 4FL2A 4TZIA 1A81A 4EIHA 2CI9A 3IN7A 2PTKA 3S8LA 2PLDA 1OO4A 2LNXA 2RORA 1X6CA 5DF6A 1NRVA 3CBLA 4K11A 3UYOA 2K79B 1PICA 1HCSB 3VS6A 1YVHA 1BF5A 1Y1UA 1YVLA 2CI8A 1O41A 3VRYA 1O47A 4U17A 1IS0A 2IUIA 1AYAA 2YU7A 2VIFA 2ABLA 3CWGA 4LUDA 5DC4A 2YSXA 3EAZA 1O4LA 1O4RA 3VS5A 4L1BB 1RPYA 1QCFA 3VRPA 1SHDA 1BLKA 5HKZA 1AOUF 3BUNB 1R1QA 2BBUA 1BMBA 5AULA 2MC1A 2HDXA 1O4OA 1LUMA 4FBNA 1CSZA 1O4EA 1JYRA 2IUHA 3GXXA 3S8OA 1FBVA 2AOAA 1O4HA 4QSYA 4OHIA 3CXLA 3S9KA 1XA6A 5J3XA 3BUOB 1FU5A 1A1AA 1AYBA 1BKLA 1B47A 3IMJA 5DC9A 2IZVA 3WA4A 1D4TA 3VRRA 5BO4A 2DM0A 1O4DA 3UF4A 1O4JA 4WWQA 1MW4A 2DLYA 1ZFPE 1X27A 3US4A 1LKLA 4XZ0A 2MQIA 5KAZA 4P9VA 5HKWA 2HDVA 5AXIA 1O4NA 4K45A 2SRCA 1O43A 5GJHA 2MRKA 2C0TA 3MAZA 1SPRA 1LUNA 1OO3A 5EHRA 2PNBA 3OB1B 4LUEA 2C9WA 2DX0A 1O46A 4EY0A 2PLEA 2EO3A 2DVJA 1NZLA 1SHAA 3BUXB 3PS5A 2HCKA 2IUGA
chains in the Genus database with same CATH superfamily
1JU5A 1LUKA 3VRNA 1AD5A 3MXCA 2AUGA 4H34A 1K9AA 3NHNA 1QADA 3C7IA 3PSJA 2AOBA 4JE4A 4OHHA 1O4IA 2EYYA 1O44A 3BUMB 2SHPA 5IBMA 1FMKA 1BHHA 3K2TA 1D1ZA 1A07A 2CR4A 3GQIB 4NWFA 4GL9E 4A4BA 3BUWB 2EU0A 1BHFA 1Y57A 2EO6A 3PFVA 2GSBA 3EACA 4DGXA 3VGOA 1F1WA 4M4ZA 4X6SA 1O4CA 3TKZA 2JYQA 1SPSA 5I6VA 3MXYA 1I3ZA 2LQNA 5CDWA 3OVEA 2KNOA 3TL0A 1QG1E 1BLJA 1KC2A 1CWEA 2HMHA 3CD3A 1BG1A 1M61A 3VS2A 1SKJA 4OHLA 1FBZA 2LQWA 1A08A 2LCTA 2DCRA 2MK2A 2L3TA 1O4BA 1RQQC 1KA6A 1WQUA 1AOTF 4OHEA 1P13A 4ROJA 4XZ1A 5DC0B 4JGHA 3VS7A 2RMXA 2K7AB 1O4MA 1AB2A 3K2MA 1KSWA 2GE9A 2OQ1A 1AYCA 4NWGA 4GPLB 3M7FA 1X0NA 2FCIA 2EKXA 1JYQA 2EL8A 4A4CA 3N7YA 1O48A 2CRHA 2OZOA 1O45A 3OP0A 2EOBA 3N84A 3VS1A 1AYDA 2ETZA 3LYVA 2KK6A 2XP1A 2CS0A 3IN8A 1KA7A 2MRJA 4D8KA 1NZVA 1M27A 3QWXX 5EG3B 4F5AA 1BKMA 1A1BA 3HCKA 1OPLA 3T04A 1Z3KA 1F2FA 1UURA 3N8MA 1GRIA 1BHHB 4K44A 2Y1MA 2CBLA 3QWYA 1FHSA 1O4AA 2QMSA 3OB2B 2EYVA 2EYZA 5EELA 3PLFB 3VS4A 5GJIA 4E68A 3VRQA 1CWDL 1FYRA 2RVFA 5EEQA 3BKBA 4OHDA 4JEGA 1BFJA 1SHBA 1UUSA 2L4KA 3IMDA 1MILA 3HHMB 1R1PA 1BM2A 3HIZB 1O42A 2DLZA 1D4WA 1O4QA 2Y1NA 1TCEA 1LCJA 1IJRA 1R1SA 1A1CA 2PNAA 2HUWA 2LNWA 4E93A 1GHUA 5EHPA 2H46E 3PSKA 3VRZA 4H1OA 3GXWA 1O4GA 2RSYA 2L6KA 3VROA 1JYUA 1O4KA 4FL3A 3VS3A 2CIAA 1CJ1A 2B3OA 3ZNIA 1G83A 4U1PA 1O4PA 2FO0A 2C0IA 2C0OA 1FU6A 1H9OA 1O4FA 2H8HA 5IBSA 4GWFA 1HCTB 4P9ZA 3KFJA 1OPKA 1LKKA 5D0JA 1A09A 1BFIA 2H5KA 1JWOA 3PJPA 3VS0A 2Y3AB 4F59A 3PQZA 1LCKA 2KGYA 3S8NA 2ECDA 1O49A 1CSYA 1RJAA 1A1EA 5HKYA 1TZEE 4K2RA 4F5BA 4DGPA 3OV1A 1LUIA 4FL2A 4TZIA 1A81A 4EIHA 2CI9A 3IN7A 2PTKA 3S8LA 2PLDA 1OO4A 2LNXA 2RORA 1X6CA 5DF6A 1NRVA 3CBLA 4K11A 3UYOA 2K79B 1PICA 1HCSB 3VS6A 1YVHA 1BF5A 1Y1UA 1YVLA 2CI8A 1O41A 3VRYA 1O47A 4U17A 1IS0A 2IUIA 1AYAA 2YU7A 2VIFA 2ABLA 3CWGA 4LUDA 5DC4A 2YSXA 3EAZA 1O4LA 1O4RA 3VS5A 4L1BB 1RPYA 1QCFA 3VRPA 1SHDA 1BLKA 5HKZA 1AOUF 3BUNB 1R1QA 2BBUA 1BMBA 5AULA 2MC1A 2HDXA 1O4OA 1LUMA 4FBNA 1CSZA 1O4EA 1JYRA 2IUHA 3GXXA 3S8OA 1FBVA 2AOAA 1O4HA 4QSYA 4OHIA 3CXLA 3S9KA 1XA6A 5J3XA 3BUOB 1FU5A 1A1AA 1AYBA 1BKLA 1B47A 3IMJA 5DC9A 2IZVA 3WA4A 1D4TA 3VRRA 5BO4A 2DM0A 1O4DA 3UF4A 1O4JA 4WWQA 1MW4A 2LRAA 2DLYA 1ZFPE 1X27A 3US4A 1LKLA 4XZ0A 2MQIA 5KAZA 4P9VA 5HKWA 2HDVA 5AXIA 1O4NA 4K45A 2SRCA 1O43A 5GJHA 2MRKA 2C0TA 3MAZA 1SPRA 1LUNA 1OO3A 5EHRA 2PNBA 3OB1B 4LUEA 2C9WA 2DX0A 1O46A 4EY0A 2PLEA 2EO3A 2DVJA 1NZLA 1SHAA 3BUXB 3PS5A 2HCKA 2IUGA
chains in the Genus database with same CATH topology
1JU5A 1LUKA 3VRNA 1AD5A 3MXCA 2AUGA 4H34A 1K9AA 3NHNA 1QADA 3C7IA 3PSJA 2AOBA 4JE4A 4OHHA 1O4IA 2EYYA 1O44A 3BUMB 2SHPA 5IBMA 1FMKA 1BHHA 1D1ZA 1A07A 2CR4A 3GQIB 4NWFA 4GL9E 4A4BA 3BUWB 2EU0A 1BHFA 1Y57A 2EO6A 3PFVA 2GSBA 3EACA 4DGXA 3VGOA 1F1WA 4M4ZA 4X6SA 1O4CA 3TKZA 2JYQA 1SPSA 5I6VA 3MXYA 1I3ZA 2LQNA 5CDWA 3OVEA 2KNOA 3TL0A 1QG1E 1BLJA 1KC2A 1CWEA 2HMHA 3CD3A 1BG1A 1M61A 3VS2A 1SKJA 4OHLA 1FBZA 2LQWA 1A08A 2LCTA 2DCRA 2MK2A 2L3TA 1O4BA 1RQQC 1KA6A 1WQUA 1AOTF 4OHEA 1P13A 4ROJA 4XZ1A 5DC0B 4JGHA 3VS7A 2RMXA 2K7AB 1O4MA 1AB2A 3K2MA 1KSWA 2GE9A 2OQ1A 1AYCA 4NWGA 4GPLB 3M7FA 1X0NA 2FCIA 2EKXA 1JYQA 2EL8A 4A4CA 3N7YA 1O48A 2CRHA 2OZOA 1O45A 3OP0A 2EOBA 3N84A 3VS1A 1AYDA 2ETZA 2KK6A 2XP1A 2CS0A 3IN8A 1KA7A 2MRJA 4D8KA 1NZVA 1M27A 3QWXX 5EG3B 4F5AA 1BKMA 1A1BA 3HCKA 1OPLA 3T04A 1Z3KA 1F2FA 1UURA 3N8MA 1GRIA 1BHHB 4K44A 2Y1MA 2CBLA 3QWYA 1FHSA 1O4AA 2QMSA 3OB2B 2EYVA 2EYZA 5EELA 3PLFB 3VS4A 5GJIA 4E68A 3VRQA 1CWDL 1FYRA 2RVFA 5EEQA 3BKBA 4OHDA 4JEGA 1BFJA 1SHBA 1UUSA 2L4KA 3IMDA 1MILA 3HHMB 1R1PA 1BM2A 3HIZB 1O42A 2DLZA 1D4WA 1O4QA 2Y1NA 1TCEA 1LCJA 1IJRA 1R1SA 1A1CA 2PNAA 2HUWA 2LNWA 4E93A 1GHUA 5EHPA 2H46E 3PSKA 3VRZA 4H1OA 3GXWA 1O4GA 2RSYA 2L6KA 3VROA 1JYUA 1O4KA 4FL3A 3VS3A 2CIAA 1CJ1A 2B3OA 3ZNIA 1G83A 4U1PA 1O4PA 2FO0A 2C0IA 2C0OA 1FU6A 1H9OA 1O4FA 2H8HA 5IBSA 4GWFA 1HCTB 4P9ZA 3KFJA 1OPKA 1LKKA 5D0JA 1A09A 1BFIA 2H5KA 1JWOA 3PJPA 3VS0A 2Y3AB 4F59A 3PQZA 1LCKA 3S8NA 2ECDA 1O49A 1CSYA 1RJAA 1A1EA 5HKYA 1TZEE 4K2RA 4F5BA 4DGPA 3OV1A 1LUIA 4FL2A 4TZIA 1A81A 4EIHA 2CI9A 3IN7A 2PTKA 3S8LA 2PLDA 1OO4A 2LNXA 2RORA 1X6CA 5DF6A 1NRVA 3CBLA 4K11A 3UYOA 2K79B 1PICA 1HCSB 3VS6A 1YVHA 1BF5A 1Y1UA 1YVLA 2CI8A 1O41A 3VRYA 1O47A 4U17A 1IS0A 2IUIA 1AYAA 2YU7A 2VIFA 2ABLA 3CWGA 4LUDA 5DC4A 2YSXA 3EAZA 1O4LA 1O4RA 3VS5A 4L1BB 1RPYA 1QCFA 3VRPA 1SHDA 1BLKA 5HKZA 1AOUF 3BUNB 1R1QA 2BBUA 1BMBA 5AULA 2MC1A 2HDXA 1O4OA 1LUMA 4FBNA 1CSZA 1O4EA 1JYRA 2IUHA 3GXXA 3S8OA 1FBVA 2AOAA 1O4HA 4QSYA 4OHIA 3CXLA 3S9KA 1XA6A 5J3XA 3BUOB 1FU5A 1A1AA 1AYBA 1BKLA 1B47A 3IMJA 5DC9A 2IZVA 3WA4A 1D4TA 3VRRA 5BO4A 2DM0A 1O4DA 3UF4A 1O4JA 4WWQA 1MW4A 2DLYA 1ZFPE 1X27A 3US4A 1LKLA 4XZ0A 2MQIA 5KAZA 4P9VA 5HKWA 2HDVA 5AXIA 1O4NA 4K45A 2SRCA 1O43A 5GJHA 2MRKA 2C0TA 3MAZA 1SPRA 1LUNA 1OO3A 5EHRA 2PNBA 3OB1B 4LUEA 2C9WA 2DX0A 1O46A 4EY0A 2PLEA 2EO3A 2DVJA 1NZLA 1SHAA 3BUXB 3PS5A 2HCKA 2IUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JU5 A;  1LUK A;  3VRN A;  1AD5 A;  3MXC A;  2AUG A;  4H34 A;  1K9A A;  3NHN A;  1QAD A;  3C7I A;  3PSJ A;  2AOB A;  4JE4 A;  4OHH A;  1O4I A;  2EYY A;  1O44 A;  3BUM B;  2SHP A;  5IBM A;  1FMK A;  1BHH A;  1D1Z A;  1A07 A;  2CR4 A;  3GQI B;  4NWF A;  4GL9 E;  4A4B A;  3BUW B;  2EU0 A;  1BHF A;  1Y57 A;  2EO6 A;  3PFV A;  2GSB A;  3EAC A;  4DGX A;  3VGO A;  1F1W A;  4M4Z A;  4X6S A;  1O4C A;  3TKZ A;  2JYQ A;  1SPS A;  5I6V A;  3MXY A;  1I3Z A;  2LQN A;  5CDW A;  3OVE A;  2KNO A;  3TL0 A;  1QG1 E;  1BLJ A;  1KC2 A;  1CWE A;  2HMH A;  3CD3 A;  1BG1 A;  1M61 A;  3VS2 A;  1SKJ A;  4OHL A;  1FBZ A;  2LQW A;  1A08 A;  2LCT A;  2DCR A;  2MK2 A;  2L3T A;  1O4B A;  1RQQ C;  1KA6 A;  1WQU A;  1AOT F;  4OHE A;  1P13 A;  4ROJ A;  4XZ1 A;  5DC0 B;  4JGH A;  3VS7 A;  2RMX A;  2K7A B;  1O4M A;  1AB2 A;  3K2M A;  1KSW A;  2GE9 A;  2OQ1 A;  1AYC A;  4NWG A;  4GPL B;  3M7F A;  1X0N A;  2FCI A;  2EKX A;  1JYQ A;  2EL8 A;  4A4C A;  3N7Y A;  1O48 A;  2CRH A;  2OZO A;  1O45 A;  3OP0 A;  2EOB A;  3N84 A;  3VS1 A;  1AYD A;  2ETZ A;  2KK6 A;  2XP1 A;  2CS0 A;  3IN8 A;  1KA7 A;  2MRJ A;  4D8K A;  1NZV A;  1M27 A;  3QWX X;  5EG3 B;  4F5A A;  1BKM A;  1A1B A;  3HCK A;  1OPL A;  3T04 A;  1Z3K A;  1F2F A;  1UUR A;  3N8M A;  1GRI A;  1BHH B;  4K44 A;  2Y1M A;  2CBL A;  3QWY A;  1FHS A;  1O4A A;  2QMS A;  3OB2 B;  2EYV A;  2EYZ A;  5EEL A;  3PLF B;  3VS4 A;  5GJI A;  4E68 A;  3VRQ A;  1CWD L;  1FYR A;  2RVF A;  5EEQ A;  3BKB A;  4OHD A;  4JEG A;  1BFJ A;  1SHB A;  1UUS A;  2L4K A;  3IMD A;  1MIL A;  3HHM B;  1R1P A;  1BM2 A;  3HIZ B;  1O42 A;  2DLZ A;  1D4W A;  1O4Q A;  2Y1N A;  1TCE A;  1LCJ A;  1IJR A;  1R1S A;  1A1C A;  2PNA A;  2HUW A;  2LNW A;  4E93 A;  1GHU A;  5EHP A;  2H46 E;  3PSK A;  3VRZ A;  4H1O A;  3GXW A;  1O4G A;  2RSY A;  2L6K A;  3VRO A;  1JYU A;  1O4K A;  4FL3 A;  3VS3 A;  2CIA A;  1CJ1 A;  2B3O A;  3ZNI A;  1G83 A;  4U1P A;  1O4P A;  2FO0 A;  2C0I A;  2C0O A;  1FU6 A;  1H9O A;  1O4F A;  2H8H A;  5IBS A;  4GWF A;  1HCT B;  4P9Z A;  3KFJ A;  1OPK A;  1LKK A;  5D0J A;  1A09 A;  1BFI A;  2H5K A;  1JWO A;  3PJP A;  3VS0 A;  2Y3A B;  4F59 A;  3PQZ A;  1LCK A;  3S8N A;  2ECD A;  1O49 A;  1CSY A;  1RJA A;  1A1E A;  5HKY A;  1TZE E;  4K2R A;  4F5B A;  4DGP A;  3OV1 A;  1LUI A;  4FL2 A;  4TZI A;  1A81 A;  4EIH A;  2CI9 A;  3IN7 A;  2PTK A;  3S8L A;  2PLD A;  1OO4 A;  2LNX A;  2ROR A;  1X6C A;  5DF6 A;  1NRV A;  3CBL A;  4K11 A;  3UYO A;  2K79 B;  1PIC A;  1HCS B;  3VS6 A;  1YVH A;  1BF5 A;  1Y1U A;  1YVL A;  2CI8 A;  1O41 A;  3VRY A;  1O47 A;  4U17 A;  1IS0 A;  2IUI A;  1AYA A;  2YU7 A;  2VIF A;  2ABL A;  3CWG A;  4LUD A;  5DC4 A;  2YSX A;  3EAZ A;  1O4L A;  1O4R A;  3VS5 A;  4L1B B;  1RPY A;  1QCF A;  3VRP A;  1SHD A;  1BLK A;  5HKZ A;  1AOU F;  3BUN B;  1R1Q A;  2BBU A;  1BMB A;  5AUL A;  2MC1 A;  2HDX A;  1O4O A;  1LUM A;  4FBN A;  1CSZ A;  1O4E A;  1JYR A;  2IUH A;  3GXX A;  3S8O A;  1FBV A;  2AOA A;  1O4H A;  4QSY A;  4OHI A;  3CXL A;  3S9K A;  1XA6 A;  5J3X A;  3BUO B;  1FU5 A;  1A1A A;  1AYB A;  1BKL A;  1B47 A;  3IMJ A;  5DC9 A;  2IZV A;  3WA4 A;  1D4T A;  3VRR A;  5BO4 A;  2DM0 A;  1O4D A;  3UF4 A;  1O4J A;  4WWQ A;  1MW4 A;  2DLY A;  1ZFP E;  1X27 A;  3US4 A;  1LKL A;  4XZ0 A;  2MQI A;  5KAZ A;  4P9V A;  5HKW A;  2HDV A;  5AXI A;  1O4N A;  4K45 A;  2SRC A;  1O43 A;  5GJH A;  2MRK A;  2C0T A;  3MAZ A;  1SPR A;  1LUN A;  1OO3 A;  5EHR A;  2PNB A;  3OB1 B;  4LUE A;  2C9W A;  2DX0 A;  1O46 A;  4EY0 A;  2PLE A;  2EO3 A;  2DVJ A;  1NZL A;  1SHA A;  3BUX B;  3PS5 A;  2HCK A;  2IUG A; 
#chains in the Genus database with same CATH topology
 1JU5 A;  1LUK A;  3VRN A;  1AD5 A;  3MXC A;  2AUG A;  4H34 A;  1K9A A;  3NHN A;  1QAD A;  3C7I A;  3PSJ A;  2AOB A;  4JE4 A;  4OHH A;  1O4I A;  2EYY A;  1O44 A;  3BUM B;  2SHP A;  5IBM A;  1FMK A;  1BHH A;  3K2T A;  1D1Z A;  1A07 A;  2CR4 A;  3GQI B;  4NWF A;  4GL9 E;  4A4B A;  3BUW B;  2EU0 A;  1BHF A;  1Y57 A;  2EO6 A;  3PFV A;  2GSB A;  3EAC A;  4DGX A;  3VGO A;  1F1W A;  4M4Z A;  4X6S A;  1O4C A;  3TKZ A;  2JYQ A;  1SPS A;  5I6V A;  3MXY A;  1I3Z A;  2LQN A;  5CDW A;  3OVE A;  2KNO A;  3TL0 A;  1QG1 E;  1BLJ A;  1KC2 A;  1CWE A;  2HMH A;  3CD3 A;  1BG1 A;  1M61 A;  3VS2 A;  1SKJ A;  4OHL A;  1FBZ A;  2LQW A;  1A08 A;  2LCT A;  2DCR A;  2MK2 A;  2L3T A;  1O4B A;  1RQQ C;  1KA6 A;  1WQU A;  1AOT F;  4OHE A;  1P13 A;  4ROJ A;  4XZ1 A;  5DC0 B;  4JGH A;  3VS7 A;  2RMX A;  2K7A B;  1O4M A;  1AB2 A;  3K2M A;  1KSW A;  2GE9 A;  2OQ1 A;  1AYC A;  4NWG A;  4GPL B;  3M7F A;  1X0N A;  2FCI A;  2EKX A;  1JYQ A;  2EL8 A;  4A4C A;  3N7Y A;  1O48 A;  2CRH A;  2OZO A;  1O45 A;  3OP0 A;  2EOB A;  3N84 A;  3VS1 A;  1AYD A;  2ETZ A;  3LYV A;  2KK6 A;  2XP1 A;  2CS0 A;  3IN8 A;  1KA7 A;  2MRJ A;  4D8K A;  1NZV A;  1M27 A;  3QWX X;  5EG3 B;  4F5A A;  1BKM A;  1A1B A;  3HCK A;  1OPL A;  3T04 A;  1Z3K A;  1F2F A;  1UUR A;  3N8M A;  1GRI A;  1BHH B;  4K44 A;  2Y1M A;  2CBL A;  3QWY A;  1FHS A;  1O4A A;  2QMS A;  3OB2 B;  2EYV A;  2EYZ A;  5EEL A;  3PLF B;  3VS4 A;  5GJI A;  4E68 A;  3VRQ A;  1CWD L;  1FYR A;  2RVF A;  5EEQ A;  3BKB A;  4OHD A;  4JEG A;  1BFJ A;  1SHB A;  1UUS A;  2L4K A;  3IMD A;  1MIL A;  3HHM B;  1R1P A;  1BM2 A;  3HIZ B;  1O42 A;  2DLZ A;  1D4W A;  1O4Q A;  2Y1N A;  1TCE A;  1LCJ A;  1IJR A;  1R1S A;  1A1C A;  2PNA A;  2HUW A;  2LNW A;  4E93 A;  1GHU A;  5EHP A;  2H46 E;  3PSK A;  3VRZ A;  4H1O A;  3GXW A;  1O4G A;  2RSY A;  2L6K A;  3VRO A;  1JYU A;  1O4K A;  4FL3 A;  3VS3 A;  2CIA A;  1CJ1 A;  2B3O A;  3ZNI A;  1G83 A;  4U1P A;  1O4P A;  2FO0 A;  2C0I A;  2C0O A;  1FU6 A;  1H9O A;  1O4F A;  2H8H A;  5IBS A;  4GWF A;  1HCT B;  4P9Z A;  3KFJ A;  1OPK A;  1LKK A;  5D0J A;  1A09 A;  1BFI A;  2H5K A;  1JWO A;  3PJP A;  3VS0 A;  2Y3A B;  4F59 A;  3PQZ A;  1LCK A;  2KGY A;  3S8N A;  2ECD A;  1O49 A;  1CSY A;  1RJA A;  1A1E A;  5HKY A;  1TZE E;  4K2R A;  4F5B A;  4DGP A;  3OV1 A;  1LUI A;  4FL2 A;  4TZI A;  1A81 A;  4EIH A;  2CI9 A;  3IN7 A;  2PTK A;  3S8L A;  2PLD A;  1OO4 A;  2LNX A;  2ROR A;  1X6C A;  5DF6 A;  1NRV A;  3CBL A;  4K11 A;  3UYO A;  2K79 B;  1PIC A;  1HCS B;  3VS6 A;  1YVH A;  1BF5 A;  1Y1U A;  1YVL A;  2CI8 A;  1O41 A;  3VRY A;  1O47 A;  4U17 A;  1IS0 A;  2IUI A;  1AYA A;  2YU7 A;  2VIF A;  2ABL A;  3CWG A;  4LUD A;  5DC4 A;  2YSX A;  3EAZ A;  1O4L A;  1O4R A;  3VS5 A;  4L1B B;  1RPY A;  1QCF A;  3VRP A;  1SHD A;  1BLK A;  5HKZ A;  1AOU F;  3BUN B;  1R1Q A;  2BBU A;  1BMB A;  5AUL A;  2MC1 A;  2HDX A;  1O4O A;  1LUM A;  4FBN A;  1CSZ A;  1O4E A;  1JYR A;  2IUH A;  3GXX A;  3S8O A;  1FBV A;  2AOA A;  1O4H A;  4QSY A;  4OHI A;  3CXL A;  3S9K A;  1XA6 A;  5J3X A;  3BUO B;  1FU5 A;  1A1A A;  1AYB A;  1BKL A;  1B47 A;  3IMJ A;  5DC9 A;  2IZV A;  3WA4 A;  1D4T A;  3VRR A;  5BO4 A;  2DM0 A;  1O4D A;  3UF4 A;  1O4J A;  4WWQ A;  1MW4 A;  2LRA A;  2DLY A;  1ZFP E;  1X27 A;  3US4 A;  1LKL A;  4XZ0 A;  2MQI A;  5KAZ A;  4P9V A;  5HKW A;  2HDV A;  5AXI A;  1O4N A;  4K45 A;  2SRC A;  1O43 A;  5GJH A;  2MRK A;  2C0T A;  3MAZ A;  1SPR A;  1LUN A;  1OO3 A;  5EHR A;  2PNB A;  3OB1 B;  4LUE A;  2C9W A;  2DX0 A;  1O46 A;  4EY0 A;  2PLE A;  2EO3 A;  2DVJ A;  1NZL A;  1SHA A;  3BUX B;  3PS5 A;  2HCK A;  2IUG A; 
#chains in the Genus database with same CATH homology
 1JU5 A;  1LUK A;  3VRN A;  1AD5 A;  3MXC A;  2AUG A;  4H34 A;  1K9A A;  3NHN A;  1QAD A;  3C7I A;  3PSJ A;  2AOB A;  4JE4 A;  4OHH A;  1O4I A;  2EYY A;  1O44 A;  3BUM B;  2SHP A;  5IBM A;  1FMK A;  1BHH A;  1D1Z A;  1A07 A;  2CR4 A;  3GQI B;  4NWF A;  4GL9 E;  4A4B A;  3BUW B;  2EU0 A;  1BHF A;  1Y57 A;  2EO6 A;  3PFV A;  2GSB A;  3EAC A;  4DGX A;  3VGO A;  1F1W A;  4M4Z A;  4X6S A;  1O4C A;  3TKZ A;  2JYQ A;  1SPS A;  5I6V A;  3MXY A;  1I3Z A;  2LQN A;  5CDW A;  3OVE A;  2KNO A;  3TL0 A;  1QG1 E;  1BLJ A;  1KC2 A;  1CWE A;  2HMH A;  3CD3 A;  1BG1 A;  1M61 A;  3VS2 A;  1SKJ A;  4OHL A;  1FBZ A;  2LQW A;  1A08 A;  2LCT A;  2DCR A;  2MK2 A;  2L3T A;  1O4B A;  1RQQ C;  1KA6 A;  1WQU A;  1AOT F;  4OHE A;  1P13 A;  4ROJ A;  4XZ1 A;  5DC0 B;  4JGH A;  3VS7 A;  2RMX A;  2K7A B;  1O4M A;  1AB2 A;  3K2M A;  1KSW A;  2GE9 A;  2OQ1 A;  1AYC A;  4NWG A;  4GPL B;  3M7F A;  1X0N A;  2FCI A;  2EKX A;  1JYQ A;  2EL8 A;  4A4C A;  3N7Y A;  1O48 A;  2CRH A;  2OZO A;  1O45 A;  3OP0 A;  2EOB A;  3N84 A;  3VS1 A;  1AYD A;  2ETZ A;  2KK6 A;  2XP1 A;  2CS0 A;  3IN8 A;  1KA7 A;  2MRJ A;  4D8K A;  1NZV A;  1M27 A;  3QWX X;  5EG3 B;  4F5A A;  1BKM A;  1A1B A;  3HCK A;  1OPL A;  3T04 A;  1Z3K A;  1F2F A;  1UUR A;  3N8M A;  1GRI A;  1BHH B;  4K44 A;  2Y1M A;  2CBL A;  3QWY A;  1FHS A;  1O4A A;  2QMS A;  3OB2 B;  2EYV A;  2EYZ A;  5EEL A;  3PLF B;  3VS4 A;  5GJI A;  4E68 A;  3VRQ A;  1CWD L;  1FYR A;  2RVF A;  5EEQ A;  3BKB A;  4OHD A;  4JEG A;  1BFJ A;  1SHB A;  1UUS A;  2L4K A;  3IMD A;  1MIL A;  3HHM B;  1R1P A;  1BM2 A;  3HIZ B;  1O42 A;  2DLZ A;  1D4W A;  1O4Q A;  2Y1N A;  1TCE A;  1LCJ A;  1IJR A;  1R1S A;  1A1C A;  2PNA A;  2HUW A;  2LNW A;  4E93 A;  1GHU A;  5EHP A;  2H46 E;  3PSK A;  3VRZ A;  4H1O A;  3GXW A;  1O4G A;  2RSY A;  2L6K A;  3VRO A;  1JYU A;  1O4K A;  4FL3 A;  3VS3 A;  2CIA A;  1CJ1 A;  2B3O A;  3ZNI A;  1G83 A;  4U1P A;  1O4P A;  2FO0 A;  2C0I A;  2C0O A;  1FU6 A;  1H9O A;  1O4F A;  2H8H A;  5IBS A;  4GWF A;  1HCT B;  4P9Z A;  3KFJ A;  1OPK A;  1LKK A;  5D0J A;  1A09 A;  1BFI A;  2H5K A;  1JWO A;  3PJP A;  3VS0 A;  2Y3A B;  4F59 A;  3PQZ A;  1LCK A;  3S8N A;  2ECD A;  1O49 A;  1CSY A;  1RJA A;  1A1E A;  5HKY A;  1TZE E;  4K2R A;  4F5B A;  4DGP A;  3OV1 A;  1LUI A;  4FL2 A;  4TZI A;  1A81 A;  4EIH A;  2CI9 A;  3IN7 A;  2PTK A;  3S8L A;  2PLD A;  1OO4 A;  2LNX A;  2ROR A;  1X6C A;  5DF6 A;  1NRV A;  3CBL A;  4K11 A;  3UYO A;  2K79 B;  1PIC A;  1HCS B;  3VS6 A;  1YVH A;  1BF5 A;  1Y1U A;  1YVL A;  2CI8 A;  1O41 A;  3VRY A;  1O47 A;  4U17 A;  1IS0 A;  2IUI A;  1AYA A;  2YU7 A;  2VIF A;  2ABL A;  3CWG A;  4LUD A;  5DC4 A;  2YSX A;  3EAZ A;  1O4L A;  1O4R A;  3VS5 A;  4L1B B;  1RPY A;  1QCF A;  3VRP A;  1SHD A;  1BLK A;  5HKZ A;  1AOU F;  3BUN B;  1R1Q A;  2BBU A;  1BMB A;  5AUL A;  2MC1 A;  2HDX A;  1O4O A;  1LUM A;  4FBN A;  1CSZ A;  1O4E A;  1JYR A;  2IUH A;  3GXX A;  3S8O A;  1FBV A;  2AOA A;  1O4H A;  4QSY A;  4OHI A;  3CXL A;  3S9K A;  1XA6 A;  5J3X A;  3BUO B;  1FU5 A;  1A1A A;  1AYB A;  1BKL A;  1B47 A;  3IMJ A;  5DC9 A;  2IZV A;  3WA4 A;  1D4T A;  3VRR A;  5BO4 A;  2DM0 A;  1O4D A;  3UF4 A;  1O4J A;  4WWQ A;  1MW4 A;  2DLY A;  1ZFP E;  1X27 A;  3US4 A;  1LKL A;  4XZ0 A;  2MQI A;  5KAZ A;  4P9V A;  5HKW A;  2HDV A;  5AXI A;  1O4N A;  4K45 A;  2SRC A;  1O43 A;  5GJH A;  2MRK A;  2C0T A;  3MAZ A;  1SPR A;  1LUN A;  1OO3 A;  5EHR A;  2PNB A;  3OB1 B;  4LUE A;  2C9W A;  2DX0 A;  1O46 A;  4EY0 A;  2PLE A;  2EO3 A;  2DVJ A;  1NZL A;  1SHA A;  3BUX B;  3PS5 A;  2HCK A;  2IUG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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