3IN8A

Crystal structure of the grb2 sh2 domain in complex with a flexible ac-ptyr-ile-asn-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
101
structure length
101
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2009-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3in8A00
2CRHA 1WQUA 3VS4A 5KAZA 1TZEE 1A08A 2K79B 3OV1A 5HKZA 2DM0A 3OP0A 3N84A 1H9OA 4A4CA 3HIZB 2KNOA 5EEQA 3PFVA 2ECDA 3UF4A 2DLZA 5D0JA 2C0IA 1JYRA 4EIHA 1PICA 3UYOA 1ZFPE 1NZLA 1NRVA 2H8HA 2IUHA 2PNBA 4P9VA 1AB2A 1BKLA 2RSYA 1D1ZA 2LNWA 3VRZA 2CI9A 2AOBA 5BO4A 3T04A 1BKMA 3IMDA 2IUIA 1R1SA 1I3ZA 2GE9A 1IS0A 1GHUA 5J3XA 2SRCA 2Y1MA 2HCKA 1RQQC 1O4CA 3US4A 1O4PA 3OB2B 2L4KA 1RJAA 2YU7A 1KA6A 3PSJA 1TCEA 4JE4A 2ETZA 4OHHA 3PS5A 1CJ1A 2LCTA 5IBMA 4X6SA 1QG1E 2MQIA 1OPLA 4U1PA 1RPYA 1YVHA 3VRQA 3CBLA 5IBSA 1JYUA 4K2RA 1AYDA 1F1WA 3TKZA 4XZ1A 5DC0B 2MRKA 1JU5A 1D4WA 1K9AA 1LUIA 2CI8A 3BUMB 1O4LA 3VS2A 5HKWA 2C9WA 4FL2A 1M27A 3BUOB 1R1PA 1X0NA 1CWEA 5DC4A 2IZVA 2YSXA 1HCTB 1O4HA 1QADA 2BBUA 4A4BA 3VS7A 3WA4A 2RMXA 2RORA 1A09A 1P13A 1X27A 3VS5A 1UUSA 2EYZA 4E93A 4U17A 1XA6A 1KSWA 1A07A 3BKBA 1O4OA 1MILA 1BG1A 2HDXA 3MAZA 1O4AA 2EO6A 2LQWA 1O46A 4DGPA 3NHNA 1FMKA 2DX0A 1G83A 2L6KA 1SHAA 1IJRA 4L1BB 2EU0A 3BUWB 3IN8A 1LUMA 1Z3KA 3PQZA 1AYBA 5AXIA 1KA7A 1MW4A 1O4KA 3HCKA 1FU5A 1O4DA 2PNAA 3VRRA 1R1QA 4LUEA 1SPSA 1OPKA 2EKXA 5HKYA 1FU6A 5DC9A 1D4TA 4FL3A 2C0OA 3KFJA 3K2MA 4OHLA 1CWDL 4QSYA 3VGOA 2EYVA 1AYCA 1FHSA 1SPRA 1BHHB 1UURA 4EY0A 3VS6A 1O49A 1O47A 4GPLB 4OHEA 3MXYA 1KC2A 1BMBA 4GWFA 3S8NA 3VS0A 1JYQA 1BF5A 2EL8A 1Y1UA 2CS0A 1O4IA 1BLKA 1BHFA 3VRNA 4XZ0A 3GXWA 3IN7A 1B47A 2HDVA 1BM2A 3ZNIA 2K7AB 1NZVA 4H1OA 2CR4A 3M7FA 5EHPA 1O4EA 1AD5A 2CBLA 3BUXB 1O4GA 5EHRA 5EELA 1O42A 2C0TA 1SKJA 4F5BA 1O48A 2DCRA 1LUNA 3VRPA 2KK6A 3C7IA 5GJHA 1LKLA 3S8LA 2B3OA 4ROJA 1LKKA 2PLEA 4DGXA 5GJIA 1O41A 2MK2A 3CD3A 2AOAA 3EAZA 4TZIA 3CWGA 2EYYA 3GXXA 2PLDA 2Y3AB 2OQ1A 1LCKA 1BLJA 3MXCA 2VIFA 1A81A 1JWOA 1HCSB 1CSYA 2DVJA 2HUWA 1CSZA 3N7YA 1Y57A 4LUDA 1O4FA 3PSKA 3BUNB 3N8MA 1O43A 4H34A 1OO4A 3OB1B 5AULA 2DLYA 1FYRA 2OZOA 1AYAA 2XP1A 5EG3B 2FO0A 1AOTF 2HMHA 3OVEA 3VS3A 1F2FA 2H46E 2IUGA 4OHIA 1O44A 2SHPA 1A1CA 4JEGA 5I6VA 1O4MA 4D8KA 1AOUF 5CDWA 1QCFA 1BFIA 1LUKA 3S8OA 3PLFB 3VRYA 2FCIA 3HHMB 2L3TA 2QMSA 1LCJA 2MC1A 4K11A 2GSBA 2RVFA 2LNXA 4GL9E 1A1BA 3S9KA 2ABLA 4NWFA 3CXLA 3EACA 1O4BA 1O4JA 4JGHA 4K45A 3VROA 1FBZA 4NWGA 5DF6A 1O4QA 1SHBA 2LQNA 3GQIB 4F5AA 4M4ZA 1BFJA 3QWYA 4WWQA 4OHDA 3QWXX 4E68A 1O4NA 3TL0A 1YVLA 4P9ZA 1OO3A 1FBVA 2Y1NA 2PTKA 2AUGA 1BHHA 3IMJA 2MRJA 1GRIA 1X6CA 1O45A 1M61A 4FBNA 3PJPA 2H5KA 1A1EA 2CIAA 2JYQA 4F59A 1SHDA 3VS1A 1A1AA 2EOBA 1O4RA 2EO3A 4K44A
chains in the Genus database with same CATH superfamily
2CRHA 1WQUA 3VS4A 5KAZA 1TZEE 1A08A 2K79B 3OV1A 5HKZA 2DM0A 3OP0A 3N84A 1H9OA 4A4CA 3HIZB 2KNOA 5EEQA 3PFVA 2ECDA 3UF4A 2DLZA 5D0JA 2C0IA 1JYRA 4EIHA 1PICA 3UYOA 1ZFPE 1NZLA 1NRVA 2H8HA 2IUHA 2PNBA 4P9VA 1AB2A 1BKLA 2RSYA 1D1ZA 2LNWA 3VRZA 2CI9A 2AOBA 5BO4A 3T04A 1BKMA 3IMDA 2IUIA 1R1SA 1I3ZA 2GE9A 1IS0A 1GHUA 5J3XA 2SRCA 2Y1MA 2HCKA 1RQQC 1O4CA 3US4A 1O4PA 3OB2B 2L4KA 1RJAA 2YU7A 1KA6A 3PSJA 1TCEA 4JE4A 2ETZA 4OHHA 3PS5A 1CJ1A 2LCTA 5IBMA 4X6SA 1QG1E 2MQIA 1OPLA 4U1PA 1RPYA 1YVHA 3VRQA 3CBLA 5IBSA 1JYUA 4K2RA 1AYDA 1F1WA 3TKZA 4XZ1A 5DC0B 2MRKA 1JU5A 1D4WA 1K9AA 1LUIA 3LYVA 2CI8A 3BUMB 1O4LA 3VS2A 5HKWA 2C9WA 4FL2A 1M27A 3BUOB 1R1PA 1X0NA 1CWEA 5DC4A 2IZVA 2YSXA 1HCTB 1O4HA 1QADA 2BBUA 4A4BA 3VS7A 3WA4A 2RMXA 2RORA 1A09A 1P13A 1X27A 3VS5A 1UUSA 2EYZA 4E93A 4U17A 1XA6A 1KSWA 1A07A 3BKBA 1O4OA 1MILA 1BG1A 2HDXA 3MAZA 1O4AA 2EO6A 2LQWA 2KGYA 1O46A 4DGPA 3NHNA 1FMKA 2DX0A 1G83A 2L6KA 1SHAA 1IJRA 4L1BB 2EU0A 3BUWB 3IN8A 1LUMA 1Z3KA 3PQZA 1AYBA 5AXIA 1KA7A 1MW4A 1O4KA 3HCKA 1FU5A 1O4DA 2PNAA 3VRRA 1R1QA 4LUEA 1SPSA 1OPKA 2EKXA 5HKYA 1FU6A 1D4TA 5DC9A 4FL3A 2C0OA 3KFJA 3K2MA 4OHLA 1CWDL 4QSYA 3VGOA 2EYVA 1AYCA 1FHSA 1SPRA 1BHHB 1UURA 4EY0A 3VS6A 1O49A 1O47A 4GPLB 4OHEA 3MXYA 1KC2A 1BMBA 4GWFA 3S8NA 3VS0A 1JYQA 1BF5A 2EL8A 1Y1UA 2CS0A 1O4IA 1BLKA 1BHFA 3VRNA 4XZ0A 3GXWA 3IN7A 1B47A 2HDVA 1BM2A 3ZNIA 2K7AB 1NZVA 4H1OA 2CR4A 3M7FA 5EHPA 1O4EA 1AD5A 2CBLA 3BUXB 1O4GA 5EHRA 5EELA 1O42A 2C0TA 1SKJA 4F5BA 1O48A 2DCRA 1LUNA 3VRPA 2KK6A 3C7IA 5GJHA 1LKLA 3S8LA 2B3OA 4ROJA 1LKKA 2PLEA 4DGXA 5GJIA 1O41A 2MK2A 3CD3A 2AOAA 3EAZA 4TZIA 3CWGA 2EYYA 3GXXA 2PLDA 2Y3AB 2OQ1A 1LCKA 1BLJA 3MXCA 2VIFA 1A81A 1JWOA 1HCSB 1CSYA 2DVJA 2HUWA 1CSZA 3N7YA 1Y57A 4LUDA 1O4FA 3PSKA 3BUNB 3N8MA 1O43A 4H34A 1OO4A 3OB1B 5AULA 2DLYA 1FYRA 2OZOA 1AYAA 2XP1A 5EG3B 2FO0A 1AOTF 2HMHA 3OVEA 3VS3A 1F2FA 2H46E 2IUGA 4OHIA 1O44A 2SHPA 1A1CA 4JEGA 5I6VA 1O4MA 4D8KA 2LRAA 1AOUF 5CDWA 1QCFA 1BFIA 1LUKA 3S8OA 3PLFB 3VRYA 2FCIA 3HHMB 2L3TA 2QMSA 1LCJA 2MC1A 4K11A 2GSBA 2RVFA 2LNXA 4GL9E 1A1BA 3S9KA 2ABLA 4NWFA 3CXLA 3EACA 1O4BA 1O4JA 4JGHA 4K45A 3VROA 1FBZA 4NWGA 5DF6A 1O4QA 1SHBA 2LQNA 3GQIB 4F5AA 4M4ZA 1BFJA 3QWYA 4WWQA 4OHDA 3QWXX 4E68A 1O4NA 3TL0A 1YVLA 4P9ZA 1OO3A 1FBVA 2Y1NA 2PTKA 2AUGA 1BHHA 3IMJA 2MRJA 1GRIA 1X6CA 1O45A 1M61A 4FBNA 3PJPA 2H5KA 1A1EA 2CIAA 2JYQA 3K2TA 4F59A 1SHDA 3VS1A 1A1AA 2EOBA 1O4RA 2EO3A 4K44A
chains in the Genus database with same CATH topology
2CRHA 1WQUA 3VS4A 5KAZA 1TZEE 1A08A 2K79B 3OV1A 5HKZA 2DM0A 3OP0A 3N84A 1H9OA 4A4CA 3HIZB 2KNOA 5EEQA 3PFVA 2ECDA 3UF4A 2DLZA 5D0JA 2C0IA 1JYRA 4EIHA 1PICA 3UYOA 1ZFPE 1NZLA 1NRVA 2H8HA 2IUHA 2PNBA 4P9VA 1AB2A 1BKLA 2RSYA 1D1ZA 2LNWA 3VRZA 2CI9A 2AOBA 5BO4A 3T04A 1BKMA 3IMDA 2IUIA 1R1SA 1I3ZA 2GE9A 1IS0A 1GHUA 5J3XA 2SRCA 2Y1MA 2HCKA 1RQQC 1O4CA 3US4A 1O4PA 3OB2B 2L4KA 1RJAA 2YU7A 1KA6A 3PSJA 1TCEA 4JE4A 2ETZA 4OHHA 3PS5A 1CJ1A 2LCTA 5IBMA 4X6SA 1QG1E 2MQIA 1OPLA 4U1PA 1RPYA 1YVHA 3VRQA 3CBLA 5IBSA 1JYUA 4K2RA 1AYDA 1F1WA 3TKZA 4XZ1A 5DC0B 2MRKA 1JU5A 1D4WA 1K9AA 1LUIA 2CI8A 3BUMB 1O4LA 3VS2A 5HKWA 2C9WA 4FL2A 1M27A 3BUOB 1R1PA 1X0NA 1CWEA 5DC4A 2IZVA 2YSXA 1HCTB 1O4HA 1QADA 2BBUA 4A4BA 3VS7A 3WA4A 2RMXA 2RORA 1A09A 1P13A 1X27A 3VS5A 1UUSA 2EYZA 4E93A 4U17A 1XA6A 1KSWA 1A07A 3BKBA 1O4OA 1MILA 1BG1A 2HDXA 3MAZA 1O4AA 2EO6A 2LQWA 1O46A 4DGPA 3NHNA 1FMKA 2DX0A 1G83A 2L6KA 1SHAA 1IJRA 4L1BB 2EU0A 3BUWB 3IN8A 1LUMA 1Z3KA 3PQZA 1AYBA 5AXIA 1KA7A 1MW4A 1O4KA 3HCKA 1FU5A 1O4DA 2PNAA 3VRRA 1R1QA 4LUEA 1SPSA 1OPKA 2EKXA 5HKYA 1FU6A 5DC9A 1D4TA 4FL3A 2C0OA 3KFJA 3K2MA 4OHLA 1CWDL 4QSYA 3VGOA 2EYVA 1AYCA 1FHSA 1SPRA 1BHHB 1UURA 4EY0A 3VS6A 1O49A 1O47A 4GPLB 4OHEA 3MXYA 1KC2A 1BMBA 4GWFA 3S8NA 3VS0A 1JYQA 1BF5A 2EL8A 1Y1UA 2CS0A 1O4IA 1BLKA 1BHFA 3VRNA 4XZ0A 3GXWA 3IN7A 1B47A 2HDVA 1BM2A 3ZNIA 2K7AB 1NZVA 4H1OA 2CR4A 3M7FA 5EHPA 1O4EA 1AD5A 2CBLA 3BUXB 1O4GA 5EHRA 5EELA 1O42A 2C0TA 1SKJA 4F5BA 1O48A 2DCRA 1LUNA 3VRPA 2KK6A 3C7IA 5GJHA 1LKLA 3S8LA 2B3OA 4ROJA 1LKKA 2PLEA 4DGXA 5GJIA 1O41A 2MK2A 3CD3A 2AOAA 3EAZA 4TZIA 3CWGA 2EYYA 3GXXA 2PLDA 2Y3AB 2OQ1A 1LCKA 1BLJA 3MXCA 2VIFA 1A81A 1JWOA 1HCSB 1CSYA 2DVJA 2HUWA 1CSZA 3N7YA 1Y57A 4LUDA 1O4FA 3PSKA 3BUNB 3N8MA 1O43A 4H34A 1OO4A 3OB1B 5AULA 2DLYA 1FYRA 2OZOA 1AYAA 2XP1A 5EG3B 2FO0A 1AOTF 2HMHA 3OVEA 3VS3A 1F2FA 2H46E 2IUGA 4OHIA 1O44A 2SHPA 1A1CA 4JEGA 5I6VA 1O4MA 4D8KA 1AOUF 5CDWA 1QCFA 1BFIA 1LUKA 3S8OA 3PLFB 3VRYA 2FCIA 3HHMB 2L3TA 2QMSA 1LCJA 2MC1A 4K11A 2GSBA 2RVFA 2LNXA 4GL9E 1A1BA 3S9KA 2ABLA 4NWFA 3CXLA 3EACA 1O4BA 1O4JA 4JGHA 4K45A 3VROA 1FBZA 4NWGA 5DF6A 1O4QA 1SHBA 2LQNA 3GQIB 4F5AA 4M4ZA 1BFJA 3QWYA 4WWQA 4OHDA 3QWXX 4E68A 1O4NA 3TL0A 1YVLA 4P9ZA 1OO3A 1FBVA 2Y1NA 2PTKA 2AUGA 1BHHA 3IMJA 2MRJA 1GRIA 1X6CA 1O45A 1M61A 4FBNA 3PJPA 2H5KA 1A1EA 2CIAA 2JYQA 4F59A 1SHDA 3VS1A 1A1AA 2EOBA 1O4RA 2EO3A 4K44A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CRH A;  1WQU A;  3VS4 A;  5KAZ A;  1TZE E;  1A08 A;  2K79 B;  3OV1 A;  5HKZ A;  2DM0 A;  3OP0 A;  3N84 A;  1H9O A;  4A4C A;  3HIZ B;  2KNO A;  5EEQ A;  3PFV A;  2ECD A;  3UF4 A;  2DLZ A;  5D0J A;  2C0I A;  1JYR A;  4EIH A;  1PIC A;  3UYO A;  1ZFP E;  1NZL A;  1NRV A;  2H8H A;  2IUH A;  2PNB A;  4P9V A;  1AB2 A;  1BKL A;  2RSY A;  1D1Z A;  2LNW A;  3VRZ A;  2CI9 A;  2AOB A;  5BO4 A;  3T04 A;  1BKM A;  3IMD A;  2IUI A;  1R1S A;  1I3Z A;  2GE9 A;  1IS0 A;  1GHU A;  5J3X A;  2SRC A;  2Y1M A;  2HCK A;  1RQQ C;  1O4C A;  3US4 A;  1O4P A;  3OB2 B;  2L4K A;  1RJA A;  2YU7 A;  1KA6 A;  3PSJ A;  1TCE A;  4JE4 A;  2ETZ A;  4OHH A;  3PS5 A;  1CJ1 A;  2LCT A;  5IBM A;  4X6S A;  1QG1 E;  2MQI A;  1OPL A;  4U1P A;  1RPY A;  1YVH A;  3VRQ A;  3CBL A;  5IBS A;  1JYU A;  4K2R A;  1AYD A;  1F1W A;  3TKZ A;  4XZ1 A;  5DC0 B;  2MRK A;  1JU5 A;  1D4W A;  1K9A A;  1LUI A;  2CI8 A;  3BUM B;  1O4L A;  3VS2 A;  5HKW A;  2C9W A;  4FL2 A;  1M27 A;  3BUO B;  1R1P A;  1X0N A;  1CWE A;  5DC4 A;  2IZV A;  2YSX A;  1HCT B;  1O4H A;  1QAD A;  2BBU A;  4A4B A;  3VS7 A;  3WA4 A;  2RMX A;  2ROR A;  1A09 A;  1P13 A;  1X27 A;  3VS5 A;  1UUS A;  2EYZ A;  4E93 A;  4U17 A;  1XA6 A;  1KSW A;  1A07 A;  3BKB A;  1O4O A;  1MIL A;  1BG1 A;  2HDX A;  3MAZ A;  1O4A A;  2EO6 A;  2LQW A;  1O46 A;  4DGP A;  3NHN A;  1FMK A;  2DX0 A;  1G83 A;  2L6K A;  1SHA A;  1IJR A;  4L1B B;  2EU0 A;  3BUW B;  3IN8 A;  1LUM A;  1Z3K A;  3PQZ A;  1AYB A;  5AXI A;  1KA7 A;  1MW4 A;  1O4K A;  3HCK A;  1FU5 A;  1O4D A;  2PNA A;  3VRR A;  1R1Q A;  4LUE A;  1SPS A;  1OPK A;  2EKX A;  5HKY A;  1FU6 A;  5DC9 A;  1D4T A;  4FL3 A;  2C0O A;  3KFJ A;  3K2M A;  4OHL A;  1CWD L;  4QSY A;  3VGO A;  2EYV A;  1AYC A;  1FHS A;  1SPR A;  1BHH B;  1UUR A;  4EY0 A;  3VS6 A;  1O49 A;  1O47 A;  4GPL B;  4OHE A;  3MXY A;  1KC2 A;  1BMB A;  4GWF A;  3S8N A;  3VS0 A;  1JYQ A;  1BF5 A;  2EL8 A;  1Y1U A;  2CS0 A;  1O4I A;  1BLK A;  1BHF A;  3VRN A;  4XZ0 A;  3GXW A;  3IN7 A;  1B47 A;  2HDV A;  1BM2 A;  3ZNI A;  2K7A B;  1NZV A;  4H1O A;  2CR4 A;  3M7F A;  5EHP A;  1O4E A;  1AD5 A;  2CBL A;  3BUX B;  1O4G A;  5EHR A;  5EEL A;  1O42 A;  2C0T A;  1SKJ A;  4F5B A;  1O48 A;  2DCR A;  1LUN A;  3VRP A;  2KK6 A;  3C7I A;  5GJH A;  1LKL A;  3S8L A;  2B3O A;  4ROJ A;  1LKK A;  2PLE A;  4DGX A;  5GJI A;  1O41 A;  2MK2 A;  3CD3 A;  2AOA A;  3EAZ A;  4TZI A;  3CWG A;  2EYY A;  3GXX A;  2PLD A;  2Y3A B;  2OQ1 A;  1LCK A;  1BLJ A;  3MXC A;  2VIF A;  1A81 A;  1JWO A;  1HCS B;  1CSY A;  2DVJ A;  2HUW A;  1CSZ A;  3N7Y A;  1Y57 A;  4LUD A;  1O4F A;  3PSK A;  3BUN B;  3N8M A;  1O43 A;  4H34 A;  1OO4 A;  3OB1 B;  5AUL A;  2DLY A;  1FYR A;  2OZO A;  1AYA A;  2XP1 A;  5EG3 B;  2FO0 A;  1AOT F;  2HMH A;  3OVE A;  3VS3 A;  1F2F A;  2H46 E;  2IUG A;  4OHI A;  1O44 A;  2SHP A;  1A1C A;  4JEG A;  5I6V A;  1O4M A;  4D8K A;  1AOU F;  5CDW A;  1QCF A;  1BFI A;  1LUK A;  3S8O A;  3PLF B;  3VRY A;  2FCI A;  3HHM B;  2L3T A;  2QMS A;  1LCJ A;  2MC1 A;  4K11 A;  2GSB A;  2RVF A;  2LNX A;  4GL9 E;  1A1B A;  3S9K A;  2ABL A;  4NWF A;  3CXL A;  3EAC A;  1O4B A;  1O4J A;  4JGH A;  4K45 A;  3VRO A;  1FBZ A;  4NWG A;  5DF6 A;  1O4Q A;  1SHB A;  2LQN A;  3GQI B;  4F5A A;  4M4Z A;  1BFJ A;  3QWY A;  4WWQ A;  4OHD A;  3QWX X;  4E68 A;  1O4N A;  3TL0 A;  1YVL A;  4P9Z A;  1OO3 A;  1FBV A;  2Y1N A;  2PTK A;  2AUG A;  1BHH A;  3IMJ A;  2MRJ A;  1GRI A;  1X6C A;  1O45 A;  1M61 A;  4FBN A;  3PJP A;  2H5K A;  1A1E A;  2CIA A;  2JYQ A;  4F59 A;  1SHD A;  3VS1 A;  1A1A A;  2EOB A;  1O4R A;  2EO3 A;  4K44 A; 
#chains in the Genus database with same CATH topology
 2CRH A;  1WQU A;  3VS4 A;  5KAZ A;  1TZE E;  1A08 A;  2K79 B;  3OV1 A;  5HKZ A;  2DM0 A;  3OP0 A;  3N84 A;  1H9O A;  4A4C A;  3HIZ B;  2KNO A;  5EEQ A;  3PFV A;  2ECD A;  3UF4 A;  2DLZ A;  5D0J A;  2C0I A;  1JYR A;  4EIH A;  1PIC A;  3UYO A;  1ZFP E;  1NZL A;  1NRV A;  2H8H A;  2IUH A;  2PNB A;  4P9V A;  1AB2 A;  1BKL A;  2RSY A;  1D1Z A;  2LNW A;  3VRZ A;  2CI9 A;  2AOB A;  5BO4 A;  3T04 A;  1BKM A;  3IMD A;  2IUI A;  1R1S A;  1I3Z A;  2GE9 A;  1IS0 A;  1GHU A;  5J3X A;  2SRC A;  2Y1M A;  2HCK A;  1RQQ C;  1O4C A;  3US4 A;  1O4P A;  3OB2 B;  2L4K A;  1RJA A;  2YU7 A;  1KA6 A;  3PSJ A;  1TCE A;  4JE4 A;  2ETZ A;  4OHH A;  3PS5 A;  1CJ1 A;  2LCT A;  5IBM A;  4X6S A;  1QG1 E;  2MQI A;  1OPL A;  4U1P A;  1RPY A;  1YVH A;  3VRQ A;  3CBL A;  5IBS A;  1JYU A;  4K2R A;  1AYD A;  1F1W A;  3TKZ A;  4XZ1 A;  5DC0 B;  2MRK A;  1JU5 A;  1D4W A;  1K9A A;  1LUI A;  3LYV A;  2CI8 A;  3BUM B;  1O4L A;  3VS2 A;  5HKW A;  2C9W A;  4FL2 A;  1M27 A;  3BUO B;  1R1P A;  1X0N A;  1CWE A;  5DC4 A;  2IZV A;  2YSX A;  1HCT B;  1O4H A;  1QAD A;  2BBU A;  4A4B A;  3VS7 A;  3WA4 A;  2RMX A;  2ROR A;  1A09 A;  1P13 A;  1X27 A;  3VS5 A;  1UUS A;  2EYZ A;  4E93 A;  4U17 A;  1XA6 A;  1KSW A;  1A07 A;  3BKB A;  1O4O A;  1MIL A;  1BG1 A;  2HDX A;  3MAZ A;  1O4A A;  2EO6 A;  2LQW A;  2KGY A;  1O46 A;  4DGP A;  3NHN A;  1FMK A;  2DX0 A;  1G83 A;  2L6K A;  1SHA A;  1IJR A;  4L1B B;  2EU0 A;  3BUW B;  3IN8 A;  1LUM A;  1Z3K A;  3PQZ A;  1AYB A;  5AXI A;  1KA7 A;  1MW4 A;  1O4K A;  3HCK A;  1FU5 A;  1O4D A;  2PNA A;  3VRR A;  1R1Q A;  4LUE A;  1SPS A;  1OPK A;  2EKX A;  5HKY A;  1FU6 A;  1D4T A;  5DC9 A;  4FL3 A;  2C0O A;  3KFJ A;  3K2M A;  4OHL A;  1CWD L;  4QSY A;  3VGO A;  2EYV A;  1AYC A;  1FHS A;  1SPR A;  1BHH B;  1UUR A;  4EY0 A;  3VS6 A;  1O49 A;  1O47 A;  4GPL B;  4OHE A;  3MXY A;  1KC2 A;  1BMB A;  4GWF A;  3S8N A;  3VS0 A;  1JYQ A;  1BF5 A;  2EL8 A;  1Y1U A;  2CS0 A;  1O4I A;  1BLK A;  1BHF A;  3VRN A;  4XZ0 A;  3GXW A;  3IN7 A;  1B47 A;  2HDV A;  1BM2 A;  3ZNI A;  2K7A B;  1NZV A;  4H1O A;  2CR4 A;  3M7F A;  5EHP A;  1O4E A;  1AD5 A;  2CBL A;  3BUX B;  1O4G A;  5EHR A;  5EEL A;  1O42 A;  2C0T A;  1SKJ A;  4F5B A;  1O48 A;  2DCR A;  1LUN A;  3VRP A;  2KK6 A;  3C7I A;  5GJH A;  1LKL A;  3S8L A;  2B3O A;  4ROJ A;  1LKK A;  2PLE A;  4DGX A;  5GJI A;  1O41 A;  2MK2 A;  3CD3 A;  2AOA A;  3EAZ A;  4TZI A;  3CWG A;  2EYY A;  3GXX A;  2PLD A;  2Y3A B;  2OQ1 A;  1LCK A;  1BLJ A;  3MXC A;  2VIF A;  1A81 A;  1JWO A;  1HCS B;  1CSY A;  2DVJ A;  2HUW A;  1CSZ A;  3N7Y A;  1Y57 A;  4LUD A;  1O4F A;  3PSK A;  3BUN B;  3N8M A;  1O43 A;  4H34 A;  1OO4 A;  3OB1 B;  5AUL A;  2DLY A;  1FYR A;  2OZO A;  1AYA A;  2XP1 A;  5EG3 B;  2FO0 A;  1AOT F;  2HMH A;  3OVE A;  3VS3 A;  1F2F A;  2H46 E;  2IUG A;  4OHI A;  1O44 A;  2SHP A;  1A1C A;  4JEG A;  5I6V A;  1O4M A;  4D8K A;  2LRA A;  1AOU F;  5CDW A;  1QCF A;  1BFI A;  1LUK A;  3S8O A;  3PLF B;  3VRY A;  2FCI A;  3HHM B;  2L3T A;  2QMS A;  1LCJ A;  2MC1 A;  4K11 A;  2GSB A;  2RVF A;  2LNX A;  4GL9 E;  1A1B A;  3S9K A;  2ABL A;  4NWF A;  3CXL A;  3EAC A;  1O4B A;  1O4J A;  4JGH A;  4K45 A;  3VRO A;  1FBZ A;  4NWG A;  5DF6 A;  1O4Q A;  1SHB A;  2LQN A;  3GQI B;  4F5A A;  4M4Z A;  1BFJ A;  3QWY A;  4WWQ A;  4OHD A;  3QWX X;  4E68 A;  1O4N A;  3TL0 A;  1YVL A;  4P9Z A;  1OO3 A;  1FBV A;  2Y1N A;  2PTK A;  2AUG A;  1BHH A;  3IMJ A;  2MRJ A;  1GRI A;  1X6C A;  1O45 A;  1M61 A;  4FBN A;  3PJP A;  2H5K A;  1A1E A;  2CIA A;  2JYQ A;  3K2T A;  4F59 A;  1SHD A;  3VS1 A;  1A1A A;  2EOB A;  1O4R A;  2EO3 A;  4K44 A; 
#chains in the Genus database with same CATH homology
 2CRH A;  1WQU A;  3VS4 A;  5KAZ A;  1TZE E;  1A08 A;  2K79 B;  3OV1 A;  5HKZ A;  2DM0 A;  3OP0 A;  3N84 A;  1H9O A;  4A4C A;  3HIZ B;  2KNO A;  5EEQ A;  3PFV A;  2ECD A;  3UF4 A;  2DLZ A;  5D0J A;  2C0I A;  1JYR A;  4EIH A;  1PIC A;  3UYO A;  1ZFP E;  1NZL A;  1NRV A;  2H8H A;  2IUH A;  2PNB A;  4P9V A;  1AB2 A;  1BKL A;  2RSY A;  1D1Z A;  2LNW A;  3VRZ A;  2CI9 A;  2AOB A;  5BO4 A;  3T04 A;  1BKM A;  3IMD A;  2IUI A;  1R1S A;  1I3Z A;  2GE9 A;  1IS0 A;  1GHU A;  5J3X A;  2SRC A;  2Y1M A;  2HCK A;  1RQQ C;  1O4C A;  3US4 A;  1O4P A;  3OB2 B;  2L4K A;  1RJA A;  2YU7 A;  1KA6 A;  3PSJ A;  1TCE A;  4JE4 A;  2ETZ A;  4OHH A;  3PS5 A;  1CJ1 A;  2LCT A;  5IBM A;  4X6S A;  1QG1 E;  2MQI A;  1OPL A;  4U1P A;  1RPY A;  1YVH A;  3VRQ A;  3CBL A;  5IBS A;  1JYU A;  4K2R A;  1AYD A;  1F1W A;  3TKZ A;  4XZ1 A;  5DC0 B;  2MRK A;  1JU5 A;  1D4W A;  1K9A A;  1LUI A;  2CI8 A;  3BUM B;  1O4L A;  3VS2 A;  5HKW A;  2C9W A;  4FL2 A;  1M27 A;  3BUO B;  1R1P A;  1X0N A;  1CWE A;  5DC4 A;  2IZV A;  2YSX A;  1HCT B;  1O4H A;  1QAD A;  2BBU A;  4A4B A;  3VS7 A;  3WA4 A;  2RMX A;  2ROR A;  1A09 A;  1P13 A;  1X27 A;  3VS5 A;  1UUS A;  2EYZ A;  4E93 A;  4U17 A;  1XA6 A;  1KSW A;  1A07 A;  3BKB A;  1O4O A;  1MIL A;  1BG1 A;  2HDX A;  3MAZ A;  1O4A A;  2EO6 A;  2LQW A;  1O46 A;  4DGP A;  3NHN A;  1FMK A;  2DX0 A;  1G83 A;  2L6K A;  1SHA A;  1IJR A;  4L1B B;  2EU0 A;  3BUW B;  3IN8 A;  1LUM A;  1Z3K A;  3PQZ A;  1AYB A;  5AXI A;  1KA7 A;  1MW4 A;  1O4K A;  3HCK A;  1FU5 A;  1O4D A;  2PNA A;  3VRR A;  1R1Q A;  4LUE A;  1SPS A;  1OPK A;  2EKX A;  5HKY A;  1FU6 A;  5DC9 A;  1D4T A;  4FL3 A;  2C0O A;  3KFJ A;  3K2M A;  4OHL A;  1CWD L;  4QSY A;  3VGO A;  2EYV A;  1AYC A;  1FHS A;  1SPR A;  1BHH B;  1UUR A;  4EY0 A;  3VS6 A;  1O49 A;  1O47 A;  4GPL B;  4OHE A;  3MXY A;  1KC2 A;  1BMB A;  4GWF A;  3S8N A;  3VS0 A;  1JYQ A;  1BF5 A;  2EL8 A;  1Y1U A;  2CS0 A;  1O4I A;  1BLK A;  1BHF A;  3VRN A;  4XZ0 A;  3GXW A;  3IN7 A;  1B47 A;  2HDV A;  1BM2 A;  3ZNI A;  2K7A B;  1NZV A;  4H1O A;  2CR4 A;  3M7F A;  5EHP A;  1O4E A;  1AD5 A;  2CBL A;  3BUX B;  1O4G A;  5EHR A;  5EEL A;  1O42 A;  2C0T A;  1SKJ A;  4F5B A;  1O48 A;  2DCR A;  1LUN A;  3VRP A;  2KK6 A;  3C7I A;  5GJH A;  1LKL A;  3S8L A;  2B3O A;  4ROJ A;  1LKK A;  2PLE A;  4DGX A;  5GJI A;  1O41 A;  2MK2 A;  3CD3 A;  2AOA A;  3EAZ A;  4TZI A;  3CWG A;  2EYY A;  3GXX A;  2PLD A;  2Y3A B;  2OQ1 A;  1LCK A;  1BLJ A;  3MXC A;  2VIF A;  1A81 A;  1JWO A;  1HCS B;  1CSY A;  2DVJ A;  2HUW A;  1CSZ A;  3N7Y A;  1Y57 A;  4LUD A;  1O4F A;  3PSK A;  3BUN B;  3N8M A;  1O43 A;  4H34 A;  1OO4 A;  3OB1 B;  5AUL A;  2DLY A;  1FYR A;  2OZO A;  1AYA A;  2XP1 A;  5EG3 B;  2FO0 A;  1AOT F;  2HMH A;  3OVE A;  3VS3 A;  1F2F A;  2H46 E;  2IUG A;  4OHI A;  1O44 A;  2SHP A;  1A1C A;  4JEG A;  5I6V A;  1O4M A;  4D8K A;  1AOU F;  5CDW A;  1QCF A;  1BFI A;  1LUK A;  3S8O A;  3PLF B;  3VRY A;  2FCI A;  3HHM B;  2L3T A;  2QMS A;  1LCJ A;  2MC1 A;  4K11 A;  2GSB A;  2RVF A;  2LNX A;  4GL9 E;  1A1B A;  3S9K A;  2ABL A;  4NWF A;  3CXL A;  3EAC A;  1O4B A;  1O4J A;  4JGH A;  4K45 A;  3VRO A;  1FBZ A;  4NWG A;  5DF6 A;  1O4Q A;  1SHB A;  2LQN A;  3GQI B;  4F5A A;  4M4Z A;  1BFJ A;  3QWY A;  4WWQ A;  4OHD A;  3QWX X;  4E68 A;  1O4N A;  3TL0 A;  1YVL A;  4P9Z A;  1OO3 A;  1FBV A;  2Y1N A;  2PTK A;  2AUG A;  1BHH A;  3IMJ A;  2MRJ A;  1GRI A;  1X6C A;  1O45 A;  1M61 A;  4FBN A;  3PJP A;  2H5K A;  1A1E A;  2CIA A;  2JYQ A;  4F59 A;  1SHD A;  3VS1 A;  1A1A A;  2EOB A;  1O4R A;  2EO3 A;  4K44 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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