3KFJA

Crystal structure of the grb2 sh2 domain in complex with a flexible ac-py-e-n-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
100
structure length
100
Chain Sequence
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2009-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3kfjA00
4LUEA 1KSWA 3QWXX 3OVEA 5BO4A 2Y3AB 1A1EA 3VS6A 4D8KA 2C0IA 1JWOA 2RSYA 2C0TA 1RQQC 1FU5A 2YU7A 3MAZA 2OQ1A 4E93A 3PS5A 3OB2B 2DCRA 3GXXA 4K2RA 1H9OA 1BMBA 2L6KA 1O4EA 4XZ0A 1F2FA 1KA7A 3VS1A 2MRJA 3HHMB 1A08A 5EEQA 3M7FA 1JYUA 3MXCA 2PNAA 1K9AA 4P9ZA 3N7YA 4OHEA 1OO3A 3VRNA 4JGHA 3VRYA 4H1OA 1FBVA 1Y57A 1YVLA 2YSXA 3VROA 2EYZA 5HKWA 1O4PA 5HKZA 5GJHA 1O41A 1JYQA 1O47A 1NRVA 4F59A 1BFIA 1CWEA 3PJPA 1LUNA 4K11A 2K79B 3CWGA 4OHLA 1LKLA 3VGOA 1O43A 4H34A 1A1CA 5GJIA 1PICA 1D1ZA 2MC1A 2QMSA 3PSJA 1R1SA 1X27A 3VRRA 5EHPA 2Y1MA 3BUWB 1A07A 3HIZB 3GXWA 2C0OA 1AYAA 1I3ZA 1OPKA 2MRKA 1MW4A 2GSBA 3PSKA 2CI8A 3GQIB 4K45A 2FCIA 1OPLA 1JU5A 3S8OA 2ECDA 1SHBA 1NZVA 4OHDA 4FL2A 5D0JA 2EU0A 1O48A 1R1QA 2PLEA 4FBNA 2MQIA 2LCTA 2ETZA 2EYYA 3IMDA 5KAZA 1O4NA 5DF6A 2EKXA 1WQUA 1MILA 4GWFA 2CI9A 1F1WA 2OZOA 3IMJA 1BLKA 4EY0A 3BKBA 1O4FA 4TZIA 4FL3A 4XZ1A 2C9WA 2BBUA 2EOBA 5IBMA 5DC9A 1UUSA 2PTKA 1X6CA 5J3XA 1BLJA 3PFVA 1CWDL 3CD3A 4F5AA 1GRIA 3OV1A 1QG1E 3S8NA 2KK6A 3VS4A 2DX0A 1AYCA 1SPRA 1G83A 1A1AA 4OHHA 1O4BA 1KA6A 3S8LA 1BHHB 1JYRA 4K44A 2SRCA 3IN7A 5EHRA 2CR4A 2AUGA 2ABLA 3S9KA 1CSYA 3IN8A 2HDXA 3BUXB 1RPYA 5I6VA 4NWFA 4A4BA 2CIAA 3PLFB 1R1PA 1O4JA 1O4OA 1TCEA 2LQWA 2IZVA 1O4IA 2L3TA 1SHAA 2XP1A 4ROJA 2CBLA 1X0NA 1AB2A 4WWQA 1ZFPE 3VS2A 4A4CA 4L1BB 2K7AB 2RORA 2EO3A 1SKJA 2L4KA 1FYRA 1FU6A 1O42A 2KNOA 1HCSB 2H46E 2VIFA 1AOTF 3C7IA 2DLYA 1O4HA 2EL8A 3VS5A 3N8MA 3BUMB 4DGPA 1IJRA 2FO0A 4M4ZA 3PQZA 1AD5A 1KC2A 1O4AA 3VS3A 1O45A 5EG3B 1O49A 4QSYA 1CJ1A 2PLDA 1OO4A 1IS0A 5HKYA 4OHIA 2CS0A 4U17A 2B3OA 5CDWA 3MXYA 2Y1NA 2HUWA 4JE4A 1D4WA 1LUMA 3KFJA 4NWGA 1SHDA 4P9VA 3QWYA 2CRHA 4X6SA 3VRQA 3VRPA 1B47A 1RJAA 4DGXA 1BKLA 1AYDA 3K2MA 2HCKA 1LCKA 1FMKA 3ZNIA 1UURA 1TZEE 1AYBA 1D4TA 3OP0A 1LUKA 1QADA 2IUIA 2EYVA 1O4MA 2EO6A 3CXLA 4GPLB 3WA4A 5AXIA 1Z3KA 2AOAA 3CBLA 3VS0A 1O4QA 3VRZA 1O4GA 2H5KA 1O4DA 1XA6A 5DC0B 1FHSA 1LUIA 3BUNB 1BHFA 1O4CA 3UYOA 2MK2A 1A09A 4JEGA 2RMXA 4EIHA 1YVHA 1SPSA 1BHHA 2IUGA 3N84A 1NZLA 1LKKA 3TKZA 1O4LA 4F5BA 1HCTB 1BKMA 1FBZA 1QCFA 2IUHA 2DVJA 4U1PA 5EELA 1O44A 1O46A 2AOBA 1O4RA 1BFJA 2LQNA 3TL0A 1BG1A 2H8HA 5DC4A 4LUDA 1LCJA 3HCKA 3EAZA 3NHNA 3T04A 2LNXA 5IBSA 1AOUF 2PNBA 2GE9A 2HDVA 2HMHA 2JYQA 1BF5A 2SHPA 1M61A 4GL9E 2DLZA 4E68A 2DM0A 1O4KA 1CSZA 1M27A 1BM2A 2RVFA 1P13A 2LNWA 3UF4A 3BUOB 1A1BA 5AULA 3VS7A 3EACA 1Y1UA 1A81A 1GHUA 3OB1B 3US4A
chains in the Genus database with same CATH superfamily
4LUEA 1KSWA 3QWXX 3OVEA 5BO4A 2Y3AB 1A1EA 3VS6A 4D8KA 2C0IA 1JWOA 2RSYA 2C0TA 1RQQC 1FU5A 2YU7A 3MAZA 2OQ1A 4E93A 3PS5A 3OB2B 2DCRA 3GXXA 4K2RA 1H9OA 1BMBA 2L6KA 1O4EA 4XZ0A 1F2FA 1KA7A 3VS1A 2MRJA 3HHMB 1A08A 5EEQA 3M7FA 1JYUA 3MXCA 2PNAA 1K9AA 4P9ZA 2LRAA 3N7YA 4OHEA 1OO3A 3VRNA 4JGHA 3K2TA 3VRYA 4H1OA 1FBVA 1Y57A 1YVLA 2YSXA 3VROA 2EYZA 5HKWA 1O4PA 5HKZA 3LYVA 1O41A 1JYQA 5GJHA 1O47A 1NRVA 4F59A 1BFIA 1CWEA 3PJPA 1LUNA 4K11A 2K79B 3CWGA 4OHLA 1LKLA 3VGOA 1O43A 4H34A 1A1CA 5GJIA 1PICA 1D1ZA 2MC1A 2QMSA 3PSJA 1R1SA 1X27A 3VRRA 5EHPA 2Y1MA 3BUWB 1A07A 3HIZB 3GXWA 2C0OA 1AYAA 1I3ZA 1OPKA 2MRKA 1MW4A 2GSBA 3PSKA 2CI8A 3GQIB 4K45A 2FCIA 1OPLA 1JU5A 3S8OA 2ECDA 1SHBA 1NZVA 4OHDA 4FL2A 5D0JA 2EU0A 1O48A 1R1QA 2PLEA 4FBNA 2MQIA 2LCTA 2ETZA 2EYYA 3IMDA 5KAZA 1O4NA 5DF6A 2EKXA 1WQUA 1MILA 4GWFA 2CI9A 1F1WA 2OZOA 3IMJA 1BLKA 4EY0A 3BKBA 1O4FA 4TZIA 4FL3A 4XZ1A 2C9WA 2BBUA 2EOBA 5IBMA 5DC9A 1UUSA 2PTKA 1X6CA 5J3XA 1BLJA 3PFVA 1CWDL 3CD3A 4F5AA 1GRIA 3OV1A 1QG1E 3S8NA 2KK6A 3VS4A 2DX0A 1AYCA 1SPRA 1G83A 1A1AA 4OHHA 1O4BA 1KA6A 3S8LA 1BHHB 1JYRA 4K44A 2SRCA 3IN7A 5EHRA 2CR4A 2AUGA 2ABLA 3S9KA 1CSYA 3IN8A 2HDXA 3BUXB 1RPYA 5I6VA 4NWFA 4A4BA 2CIAA 3PLFB 1R1PA 1O4JA 1O4OA 1TCEA 2LQWA 2IZVA 1O4IA 2L3TA 1SHAA 2XP1A 4ROJA 2CBLA 1X0NA 1AB2A 4WWQA 1ZFPE 3VS2A 4A4CA 4L1BB 2K7AB 2RORA 2EO3A 1SKJA 2L4KA 1FYRA 1FU6A 1O42A 2KNOA 1HCSB 2H46E 2VIFA 1AOTF 3C7IA 2DLYA 1O4HA 2EL8A 3VS5A 3N8MA 3BUMB 4DGPA 1IJRA 2FO0A 4M4ZA 3PQZA 1AD5A 1KC2A 1O4AA 3VS3A 1O45A 5EG3B 1O49A 4QSYA 1CJ1A 2PLDA 1OO4A 1IS0A 5HKYA 4OHIA 2CS0A 4U17A 2B3OA 5CDWA 3MXYA 2Y1NA 2HUWA 4JE4A 1D4WA 1LUMA 3KFJA 4NWGA 2KGYA 1SHDA 4P9VA 3QWYA 2CRHA 4X6SA 3VRQA 3VRPA 1B47A 1RJAA 4DGXA 1BKLA 1AYDA 3K2MA 2HCKA 1LCKA 1FMKA 3ZNIA 1UURA 1TZEE 1AYBA 1D4TA 3OP0A 1LUKA 1QADA 2IUIA 2EYVA 1O4MA 2EO6A 3CXLA 4GPLB 3WA4A 5AXIA 1Z3KA 2AOAA 3CBLA 3VS0A 1O4QA 3VRZA 1O4GA 2H5KA 1O4DA 1XA6A 5DC0B 1FHSA 1LUIA 3BUNB 1BHFA 1O4CA 3UYOA 2MK2A 1A09A 4JEGA 2RMXA 4EIHA 1YVHA 1SPSA 1BHHA 2IUGA 3N84A 1NZLA 1LKKA 3TKZA 1O4LA 4F5BA 1HCTB 1BKMA 1FBZA 1QCFA 2IUHA 2DVJA 4U1PA 5EELA 1O44A 1O46A 2AOBA 1O4RA 1BFJA 2LQNA 3TL0A 1BG1A 2H8HA 5DC4A 4LUDA 1LCJA 3HCKA 3EAZA 3NHNA 3T04A 2LNXA 5IBSA 1AOUF 2PNBA 2GE9A 2HDVA 2HMHA 2JYQA 1BF5A 2SHPA 1M61A 4GL9E 2DLZA 4E68A 2DM0A 1O4KA 1CSZA 1M27A 1BM2A 2RVFA 1P13A 2LNWA 3UF4A 3BUOB 1A1BA 5AULA 3VS7A 3EACA 1Y1UA 1A81A 1GHUA 3OB1B 3US4A
chains in the Genus database with same CATH topology
4LUEA 1KSWA 3QWXX 3OVEA 5BO4A 2Y3AB 1A1EA 3VS6A 4D8KA 2C0IA 1JWOA 2RSYA 2C0TA 1RQQC 1FU5A 2YU7A 3MAZA 2OQ1A 4E93A 3PS5A 3OB2B 2DCRA 3GXXA 4K2RA 1H9OA 1BMBA 2L6KA 1O4EA 4XZ0A 1F2FA 1KA7A 3VS1A 2MRJA 3HHMB 1A08A 5EEQA 3M7FA 1JYUA 3MXCA 2PNAA 1K9AA 4P9ZA 3N7YA 4OHEA 1OO3A 3VRNA 4JGHA 3VRYA 4H1OA 1FBVA 1Y57A 1YVLA 2YSXA 3VROA 2EYZA 5HKWA 1O4PA 5HKZA 5GJHA 1O41A 1JYQA 1O47A 1NRVA 4F59A 1BFIA 1CWEA 3PJPA 1LUNA 4K11A 2K79B 3CWGA 4OHLA 1LKLA 3VGOA 1O43A 4H34A 1A1CA 5GJIA 1PICA 1D1ZA 2MC1A 2QMSA 3PSJA 1R1SA 1X27A 3VRRA 5EHPA 2Y1MA 3BUWB 1A07A 3HIZB 3GXWA 2C0OA 1AYAA 1I3ZA 1OPKA 2MRKA 1MW4A 2GSBA 3PSKA 2CI8A 3GQIB 4K45A 2FCIA 1OPLA 1JU5A 3S8OA 2ECDA 1SHBA 1NZVA 4OHDA 4FL2A 5D0JA 2EU0A 1O48A 1R1QA 2PLEA 4FBNA 2MQIA 2LCTA 2ETZA 2EYYA 3IMDA 5KAZA 1O4NA 5DF6A 2EKXA 1WQUA 1MILA 4GWFA 2CI9A 1F1WA 2OZOA 3IMJA 1BLKA 4EY0A 3BKBA 1O4FA 4TZIA 4FL3A 4XZ1A 2C9WA 2BBUA 2EOBA 5IBMA 5DC9A 1UUSA 2PTKA 1X6CA 5J3XA 1BLJA 3PFVA 1CWDL 3CD3A 4F5AA 1GRIA 3OV1A 1QG1E 3S8NA 2KK6A 3VS4A 2DX0A 1AYCA 1SPRA 1G83A 1A1AA 4OHHA 1O4BA 1KA6A 3S8LA 1BHHB 1JYRA 4K44A 2SRCA 3IN7A 5EHRA 2CR4A 2AUGA 2ABLA 3S9KA 1CSYA 3IN8A 2HDXA 3BUXB 1RPYA 5I6VA 4NWFA 4A4BA 2CIAA 3PLFB 1R1PA 1O4JA 1O4OA 1TCEA 2LQWA 2IZVA 1O4IA 2L3TA 1SHAA 2XP1A 4ROJA 2CBLA 1X0NA 1AB2A 4WWQA 1ZFPE 3VS2A 4A4CA 4L1BB 2K7AB 2RORA 2EO3A 1SKJA 2L4KA 1FYRA 1FU6A 1O42A 2KNOA 1HCSB 2H46E 2VIFA 1AOTF 3C7IA 2DLYA 1O4HA 2EL8A 3VS5A 3N8MA 3BUMB 4DGPA 1IJRA 2FO0A 4M4ZA 3PQZA 1AD5A 1KC2A 1O4AA 3VS3A 1O45A 5EG3B 1O49A 4QSYA 1CJ1A 2PLDA 1OO4A 1IS0A 5HKYA 4OHIA 2CS0A 4U17A 2B3OA 5CDWA 3MXYA 2Y1NA 2HUWA 4JE4A 1D4WA 1LUMA 3KFJA 4NWGA 1SHDA 4P9VA 3QWYA 2CRHA 4X6SA 3VRQA 3VRPA 1B47A 1RJAA 4DGXA 1BKLA 1AYDA 3K2MA 2HCKA 1LCKA 1FMKA 3ZNIA 1UURA 1TZEE 1AYBA 1D4TA 3OP0A 1LUKA 1QADA 2IUIA 2EYVA 1O4MA 2EO6A 3CXLA 4GPLB 3WA4A 5AXIA 1Z3KA 2AOAA 3CBLA 3VS0A 1O4QA 3VRZA 1O4GA 2H5KA 1O4DA 1XA6A 5DC0B 1FHSA 1LUIA 3BUNB 1BHFA 1O4CA 3UYOA 2MK2A 1A09A 4JEGA 2RMXA 4EIHA 1YVHA 1SPSA 1BHHA 2IUGA 3N84A 1NZLA 1LKKA 3TKZA 1O4LA 4F5BA 1HCTB 1BKMA 1FBZA 1QCFA 2IUHA 2DVJA 4U1PA 5EELA 1O44A 1O46A 2AOBA 1O4RA 1BFJA 2LQNA 3TL0A 1BG1A 2H8HA 5DC4A 4LUDA 1LCJA 3HCKA 3EAZA 3NHNA 3T04A 2LNXA 5IBSA 1AOUF 2PNBA 2GE9A 2HDVA 2HMHA 2JYQA 1BF5A 2SHPA 1M61A 4GL9E 2DLZA 4E68A 2DM0A 1O4KA 1CSZA 1M27A 1BM2A 2RVFA 1P13A 2LNWA 3UF4A 3BUOB 1A1BA 5AULA 3VS7A 3EACA 1Y1UA 1A81A 1GHUA 3OB1B 3US4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LUE A;  1KSW A;  3QWX X;  3OVE A;  5BO4 A;  2Y3A B;  1A1E A;  3VS6 A;  4D8K A;  2C0I A;  1JWO A;  2RSY A;  2C0T A;  1RQQ C;  1FU5 A;  2YU7 A;  3MAZ A;  2OQ1 A;  4E93 A;  3PS5 A;  3OB2 B;  2DCR A;  3GXX A;  4K2R A;  1H9O A;  1BMB A;  2L6K A;  1O4E A;  4XZ0 A;  1F2F A;  1KA7 A;  3VS1 A;  2MRJ A;  3HHM B;  1A08 A;  5EEQ A;  3M7F A;  1JYU A;  3MXC A;  2PNA A;  1K9A A;  4P9Z A;  3N7Y A;  4OHE A;  1OO3 A;  3VRN A;  4JGH A;  3VRY A;  4H1O A;  1FBV A;  1Y57 A;  1YVL A;  2YSX A;  3VRO A;  2EYZ A;  5HKW A;  1O4P A;  5HKZ A;  5GJH A;  1O41 A;  1JYQ A;  1O47 A;  1NRV A;  4F59 A;  1BFI A;  1CWE A;  3PJP A;  1LUN A;  4K11 A;  2K79 B;  3CWG A;  4OHL A;  1LKL A;  3VGO A;  1O43 A;  4H34 A;  1A1C A;  5GJI A;  1PIC A;  1D1Z A;  2MC1 A;  2QMS A;  3PSJ A;  1R1S A;  1X27 A;  3VRR A;  5EHP A;  2Y1M A;  3BUW B;  1A07 A;  3HIZ B;  3GXW A;  2C0O A;  1AYA A;  1I3Z A;  1OPK A;  2MRK A;  1MW4 A;  2GSB A;  3PSK A;  2CI8 A;  3GQI B;  4K45 A;  2FCI A;  1OPL A;  1JU5 A;  3S8O A;  2ECD A;  1SHB A;  1NZV A;  4OHD A;  4FL2 A;  5D0J A;  2EU0 A;  1O48 A;  1R1Q A;  2PLE A;  4FBN A;  2MQI A;  2LCT A;  2ETZ A;  2EYY A;  3IMD A;  5KAZ A;  1O4N A;  5DF6 A;  2EKX A;  1WQU A;  1MIL A;  4GWF A;  2CI9 A;  1F1W A;  2OZO A;  3IMJ A;  1BLK A;  4EY0 A;  3BKB A;  1O4F A;  4TZI A;  4FL3 A;  4XZ1 A;  2C9W A;  2BBU A;  2EOB A;  5IBM A;  5DC9 A;  1UUS A;  2PTK A;  1X6C A;  5J3X A;  1BLJ A;  3PFV A;  1CWD L;  3CD3 A;  4F5A A;  1GRI A;  3OV1 A;  1QG1 E;  3S8N A;  2KK6 A;  3VS4 A;  2DX0 A;  1AYC A;  1SPR A;  1G83 A;  1A1A A;  4OHH A;  1O4B A;  1KA6 A;  3S8L A;  1BHH B;  1JYR A;  4K44 A;  2SRC A;  3IN7 A;  5EHR A;  2CR4 A;  2AUG A;  2ABL A;  3S9K A;  1CSY A;  3IN8 A;  2HDX A;  3BUX B;  1RPY A;  5I6V A;  4NWF A;  4A4B A;  2CIA A;  3PLF B;  1R1P A;  1O4J A;  1O4O A;  1TCE A;  2LQW A;  2IZV A;  1O4I A;  2L3T A;  1SHA A;  2XP1 A;  4ROJ A;  2CBL A;  1X0N A;  1AB2 A;  4WWQ A;  1ZFP E;  3VS2 A;  4A4C A;  4L1B B;  2K7A B;  2ROR A;  2EO3 A;  1SKJ A;  2L4K A;  1FYR A;  1FU6 A;  1O42 A;  2KNO A;  1HCS B;  2H46 E;  2VIF A;  1AOT F;  3C7I A;  2DLY A;  1O4H A;  2EL8 A;  3VS5 A;  3N8M A;  3BUM B;  4DGP A;  1IJR A;  2FO0 A;  4M4Z A;  3PQZ A;  1AD5 A;  1KC2 A;  1O4A A;  3VS3 A;  1O45 A;  5EG3 B;  1O49 A;  4QSY A;  1CJ1 A;  2PLD A;  1OO4 A;  1IS0 A;  5HKY A;  4OHI A;  2CS0 A;  4U17 A;  2B3O A;  5CDW A;  3MXY A;  2Y1N A;  2HUW A;  4JE4 A;  1D4W A;  1LUM A;  3KFJ A;  4NWG A;  1SHD A;  4P9V A;  3QWY A;  2CRH A;  4X6S A;  3VRQ A;  3VRP A;  1B47 A;  1RJA A;  4DGX A;  1BKL A;  1AYD A;  3K2M A;  2HCK A;  1LCK A;  1FMK A;  3ZNI A;  1UUR A;  1TZE E;  1AYB A;  1D4T A;  3OP0 A;  1LUK A;  1QAD A;  2IUI A;  2EYV A;  1O4M A;  2EO6 A;  3CXL A;  4GPL B;  3WA4 A;  5AXI A;  1Z3K A;  2AOA A;  3CBL A;  3VS0 A;  1O4Q A;  3VRZ A;  1O4G A;  2H5K A;  1O4D A;  1XA6 A;  5DC0 B;  1FHS A;  1LUI A;  3BUN B;  1BHF A;  1O4C A;  3UYO A;  2MK2 A;  1A09 A;  4JEG A;  2RMX A;  4EIH A;  1YVH A;  1SPS A;  1BHH A;  2IUG A;  3N84 A;  1NZL A;  1LKK A;  3TKZ A;  1O4L A;  4F5B A;  1HCT B;  1BKM A;  1FBZ A;  1QCF A;  2IUH A;  2DVJ A;  4U1P A;  5EEL A;  1O44 A;  1O46 A;  2AOB A;  1O4R A;  1BFJ A;  2LQN A;  3TL0 A;  1BG1 A;  2H8H A;  5DC4 A;  4LUD A;  1LCJ A;  3HCK A;  3EAZ A;  3NHN A;  3T04 A;  2LNX A;  5IBS A;  1AOU F;  2PNB A;  2GE9 A;  2HDV A;  2HMH A;  2JYQ A;  1BF5 A;  2SHP A;  1M61 A;  4GL9 E;  2DLZ A;  4E68 A;  2DM0 A;  1O4K A;  1CSZ A;  1M27 A;  1BM2 A;  2RVF A;  1P13 A;  2LNW A;  3UF4 A;  3BUO B;  1A1B A;  5AUL A;  3VS7 A;  3EAC A;  1Y1U A;  1A81 A;  1GHU A;  3OB1 B;  3US4 A; 
#chains in the Genus database with same CATH topology
 4LUE A;  1KSW A;  3QWX X;  3OVE A;  5BO4 A;  2Y3A B;  1A1E A;  3VS6 A;  4D8K A;  2C0I A;  1JWO A;  2RSY A;  2C0T A;  1RQQ C;  1FU5 A;  2YU7 A;  3MAZ A;  2OQ1 A;  4E93 A;  3PS5 A;  3OB2 B;  2DCR A;  3GXX A;  4K2R A;  1H9O A;  1BMB A;  2L6K A;  1O4E A;  4XZ0 A;  1F2F A;  1KA7 A;  3VS1 A;  2MRJ A;  3HHM B;  1A08 A;  5EEQ A;  3M7F A;  1JYU A;  3MXC A;  2PNA A;  1K9A A;  4P9Z A;  2LRA A;  3N7Y A;  4OHE A;  1OO3 A;  3VRN A;  4JGH A;  3K2T A;  3VRY A;  4H1O A;  1FBV A;  1Y57 A;  1YVL A;  2YSX A;  3VRO A;  2EYZ A;  5HKW A;  1O4P A;  5HKZ A;  3LYV A;  1O41 A;  1JYQ A;  5GJH A;  1O47 A;  1NRV A;  4F59 A;  1BFI A;  1CWE A;  3PJP A;  1LUN A;  4K11 A;  2K79 B;  3CWG A;  4OHL A;  1LKL A;  3VGO A;  1O43 A;  4H34 A;  1A1C A;  5GJI A;  1PIC A;  1D1Z A;  2MC1 A;  2QMS A;  3PSJ A;  1R1S A;  1X27 A;  3VRR A;  5EHP A;  2Y1M A;  3BUW B;  1A07 A;  3HIZ B;  3GXW A;  2C0O A;  1AYA A;  1I3Z A;  1OPK A;  2MRK A;  1MW4 A;  2GSB A;  3PSK A;  2CI8 A;  3GQI B;  4K45 A;  2FCI A;  1OPL A;  1JU5 A;  3S8O A;  2ECD A;  1SHB A;  1NZV A;  4OHD A;  4FL2 A;  5D0J A;  2EU0 A;  1O48 A;  1R1Q A;  2PLE A;  4FBN A;  2MQI A;  2LCT A;  2ETZ A;  2EYY A;  3IMD A;  5KAZ A;  1O4N A;  5DF6 A;  2EKX A;  1WQU A;  1MIL A;  4GWF A;  2CI9 A;  1F1W A;  2OZO A;  3IMJ A;  1BLK A;  4EY0 A;  3BKB A;  1O4F A;  4TZI A;  4FL3 A;  4XZ1 A;  2C9W A;  2BBU A;  2EOB A;  5IBM A;  5DC9 A;  1UUS A;  2PTK A;  1X6C A;  5J3X A;  1BLJ A;  3PFV A;  1CWD L;  3CD3 A;  4F5A A;  1GRI A;  3OV1 A;  1QG1 E;  3S8N A;  2KK6 A;  3VS4 A;  2DX0 A;  1AYC A;  1SPR A;  1G83 A;  1A1A A;  4OHH A;  1O4B A;  1KA6 A;  3S8L A;  1BHH B;  1JYR A;  4K44 A;  2SRC A;  3IN7 A;  5EHR A;  2CR4 A;  2AUG A;  2ABL A;  3S9K A;  1CSY A;  3IN8 A;  2HDX A;  3BUX B;  1RPY A;  5I6V A;  4NWF A;  4A4B A;  2CIA A;  3PLF B;  1R1P A;  1O4J A;  1O4O A;  1TCE A;  2LQW A;  2IZV A;  1O4I A;  2L3T A;  1SHA A;  2XP1 A;  4ROJ A;  2CBL A;  1X0N A;  1AB2 A;  4WWQ A;  1ZFP E;  3VS2 A;  4A4C A;  4L1B B;  2K7A B;  2ROR A;  2EO3 A;  1SKJ A;  2L4K A;  1FYR A;  1FU6 A;  1O42 A;  2KNO A;  1HCS B;  2H46 E;  2VIF A;  1AOT F;  3C7I A;  2DLY A;  1O4H A;  2EL8 A;  3VS5 A;  3N8M A;  3BUM B;  4DGP A;  1IJR A;  2FO0 A;  4M4Z A;  3PQZ A;  1AD5 A;  1KC2 A;  1O4A A;  3VS3 A;  1O45 A;  5EG3 B;  1O49 A;  4QSY A;  1CJ1 A;  2PLD A;  1OO4 A;  1IS0 A;  5HKY A;  4OHI A;  2CS0 A;  4U17 A;  2B3O A;  5CDW A;  3MXY A;  2Y1N A;  2HUW A;  4JE4 A;  1D4W A;  1LUM A;  3KFJ A;  4NWG A;  2KGY A;  1SHD A;  4P9V A;  3QWY A;  2CRH A;  4X6S A;  3VRQ A;  3VRP A;  1B47 A;  1RJA A;  4DGX A;  1BKL A;  1AYD A;  3K2M A;  2HCK A;  1LCK A;  1FMK A;  3ZNI A;  1UUR A;  1TZE E;  1AYB A;  1D4T A;  3OP0 A;  1LUK A;  1QAD A;  2IUI A;  2EYV A;  1O4M A;  2EO6 A;  3CXL A;  4GPL B;  3WA4 A;  5AXI A;  1Z3K A;  2AOA A;  3CBL A;  3VS0 A;  1O4Q A;  3VRZ A;  1O4G A;  2H5K A;  1O4D A;  1XA6 A;  5DC0 B;  1FHS A;  1LUI A;  3BUN B;  1BHF A;  1O4C A;  3UYO A;  2MK2 A;  1A09 A;  4JEG A;  2RMX A;  4EIH A;  1YVH A;  1SPS A;  1BHH A;  2IUG A;  3N84 A;  1NZL A;  1LKK A;  3TKZ A;  1O4L A;  4F5B A;  1HCT B;  1BKM A;  1FBZ A;  1QCF A;  2IUH A;  2DVJ A;  4U1P A;  5EEL A;  1O44 A;  1O46 A;  2AOB A;  1O4R A;  1BFJ A;  2LQN A;  3TL0 A;  1BG1 A;  2H8H A;  5DC4 A;  4LUD A;  1LCJ A;  3HCK A;  3EAZ A;  3NHN A;  3T04 A;  2LNX A;  5IBS A;  1AOU F;  2PNB A;  2GE9 A;  2HDV A;  2HMH A;  2JYQ A;  1BF5 A;  2SHP A;  1M61 A;  4GL9 E;  2DLZ A;  4E68 A;  2DM0 A;  1O4K A;  1CSZ A;  1M27 A;  1BM2 A;  2RVF A;  1P13 A;  2LNW A;  3UF4 A;  3BUO B;  1A1B A;  5AUL A;  3VS7 A;  3EAC A;  1Y1U A;  1A81 A;  1GHU A;  3OB1 B;  3US4 A; 
#chains in the Genus database with same CATH homology
 4LUE A;  1KSW A;  3QWX X;  3OVE A;  5BO4 A;  2Y3A B;  1A1E A;  3VS6 A;  4D8K A;  2C0I A;  1JWO A;  2RSY A;  2C0T A;  1RQQ C;  1FU5 A;  2YU7 A;  3MAZ A;  2OQ1 A;  4E93 A;  3PS5 A;  3OB2 B;  2DCR A;  3GXX A;  4K2R A;  1H9O A;  1BMB A;  2L6K A;  1O4E A;  4XZ0 A;  1F2F A;  1KA7 A;  3VS1 A;  2MRJ A;  3HHM B;  1A08 A;  5EEQ A;  3M7F A;  1JYU A;  3MXC A;  2PNA A;  1K9A A;  4P9Z A;  3N7Y A;  4OHE A;  1OO3 A;  3VRN A;  4JGH A;  3VRY A;  4H1O A;  1FBV A;  1Y57 A;  1YVL A;  2YSX A;  3VRO A;  2EYZ A;  5HKW A;  1O4P A;  5HKZ A;  5GJH A;  1O41 A;  1JYQ A;  1O47 A;  1NRV A;  4F59 A;  1BFI A;  1CWE A;  3PJP A;  1LUN A;  4K11 A;  2K79 B;  3CWG A;  4OHL A;  1LKL A;  3VGO A;  1O43 A;  4H34 A;  1A1C A;  5GJI A;  1PIC A;  1D1Z A;  2MC1 A;  2QMS A;  3PSJ A;  1R1S A;  1X27 A;  3VRR A;  5EHP A;  2Y1M A;  3BUW B;  1A07 A;  3HIZ B;  3GXW A;  2C0O A;  1AYA A;  1I3Z A;  1OPK A;  2MRK A;  1MW4 A;  2GSB A;  3PSK A;  2CI8 A;  3GQI B;  4K45 A;  2FCI A;  1OPL A;  1JU5 A;  3S8O A;  2ECD A;  1SHB A;  1NZV A;  4OHD A;  4FL2 A;  5D0J A;  2EU0 A;  1O48 A;  1R1Q A;  2PLE A;  4FBN A;  2MQI A;  2LCT A;  2ETZ A;  2EYY A;  3IMD A;  5KAZ A;  1O4N A;  5DF6 A;  2EKX A;  1WQU A;  1MIL A;  4GWF A;  2CI9 A;  1F1W A;  2OZO A;  3IMJ A;  1BLK A;  4EY0 A;  3BKB A;  1O4F A;  4TZI A;  4FL3 A;  4XZ1 A;  2C9W A;  2BBU A;  2EOB A;  5IBM A;  5DC9 A;  1UUS A;  2PTK A;  1X6C A;  5J3X A;  1BLJ A;  3PFV A;  1CWD L;  3CD3 A;  4F5A A;  1GRI A;  3OV1 A;  1QG1 E;  3S8N A;  2KK6 A;  3VS4 A;  2DX0 A;  1AYC A;  1SPR A;  1G83 A;  1A1A A;  4OHH A;  1O4B A;  1KA6 A;  3S8L A;  1BHH B;  1JYR A;  4K44 A;  2SRC A;  3IN7 A;  5EHR A;  2CR4 A;  2AUG A;  2ABL A;  3S9K A;  1CSY A;  3IN8 A;  2HDX A;  3BUX B;  1RPY A;  5I6V A;  4NWF A;  4A4B A;  2CIA A;  3PLF B;  1R1P A;  1O4J A;  1O4O A;  1TCE A;  2LQW A;  2IZV A;  1O4I A;  2L3T A;  1SHA A;  2XP1 A;  4ROJ A;  2CBL A;  1X0N A;  1AB2 A;  4WWQ A;  1ZFP E;  3VS2 A;  4A4C A;  4L1B B;  2K7A B;  2ROR A;  2EO3 A;  1SKJ A;  2L4K A;  1FYR A;  1FU6 A;  1O42 A;  2KNO A;  1HCS B;  2H46 E;  2VIF A;  1AOT F;  3C7I A;  2DLY A;  1O4H A;  2EL8 A;  3VS5 A;  3N8M A;  3BUM B;  4DGP A;  1IJR A;  2FO0 A;  4M4Z A;  3PQZ A;  1AD5 A;  1KC2 A;  1O4A A;  3VS3 A;  1O45 A;  5EG3 B;  1O49 A;  4QSY A;  1CJ1 A;  2PLD A;  1OO4 A;  1IS0 A;  5HKY A;  4OHI A;  2CS0 A;  4U17 A;  2B3O A;  5CDW A;  3MXY A;  2Y1N A;  2HUW A;  4JE4 A;  1D4W A;  1LUM A;  3KFJ A;  4NWG A;  1SHD A;  4P9V A;  3QWY A;  2CRH A;  4X6S A;  3VRQ A;  3VRP A;  1B47 A;  1RJA A;  4DGX A;  1BKL A;  1AYD A;  3K2M A;  2HCK A;  1LCK A;  1FMK A;  3ZNI A;  1UUR A;  1TZE E;  1AYB A;  1D4T A;  3OP0 A;  1LUK A;  1QAD A;  2IUI A;  2EYV A;  1O4M A;  2EO6 A;  3CXL A;  4GPL B;  3WA4 A;  5AXI A;  1Z3K A;  2AOA A;  3CBL A;  3VS0 A;  1O4Q A;  3VRZ A;  1O4G A;  2H5K A;  1O4D A;  1XA6 A;  5DC0 B;  1FHS A;  1LUI A;  3BUN B;  1BHF A;  1O4C A;  3UYO A;  2MK2 A;  1A09 A;  4JEG A;  2RMX A;  4EIH A;  1YVH A;  1SPS A;  1BHH A;  2IUG A;  3N84 A;  1NZL A;  1LKK A;  3TKZ A;  1O4L A;  4F5B A;  1HCT B;  1BKM A;  1FBZ A;  1QCF A;  2IUH A;  2DVJ A;  4U1P A;  5EEL A;  1O44 A;  1O46 A;  2AOB A;  1O4R A;  1BFJ A;  2LQN A;  3TL0 A;  1BG1 A;  2H8H A;  5DC4 A;  4LUD A;  1LCJ A;  3HCK A;  3EAZ A;  3NHN A;  3T04 A;  2LNX A;  5IBS A;  1AOU F;  2PNB A;  2GE9 A;  2HDV A;  2HMH A;  2JYQ A;  1BF5 A;  2SHP A;  1M61 A;  4GL9 E;  2DLZ A;  4E68 A;  2DM0 A;  1O4K A;  1CSZ A;  1M27 A;  1BM2 A;  2RVF A;  1P13 A;  2LNW A;  3UF4 A;  3BUO B;  1A1B A;  5AUL A;  3VS7 A;  3EAC A;  1Y1U A;  1A81 A;  1GHU A;  3OB1 B;  3US4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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