3MXCA

Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications.
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2010-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3mxcA00
3PLFB 4OHEA 4P9VA 2H46E 2KNOA 1LCKA 2MRKA 1QG1E 1RPYA 1SPRA 3BUNB 1O4RA 3HIZB 1O4OA 1O4PA 5EHPA 4EIHA 2IUIA 2CI8A 1F2FA 3VRQA 3N84A 3GXXA 4P9ZA 2YSXA 3OP0A 1SKJA 4XZ0A 2B3OA 2DX0A 1M27A 3OVEA 2OQ1A 2GSBA 2LQWA 2HDVA 1CWEA 3MXCA 1LUMA 2CIAA 1AD5A 2PNAA 3PS5A 2FCIA 5BO4A 2PTKA 1X27A 2AOAA 4X6SA 1O4FA 4H1OA 4DGXA 2ABLA 2RMXA 1FHSA 4K45A 3VRZA 3QWYA 3N8MA 5GJHA 1OPLA 1X6CA 4EY0A 2Y3AB 2L4KA 1O43A 2CRHA 2DLYA 4JGHA 1O44A 2K7AB 1JYQA 2FO0A 2LCTA 1WQUA 1HCSB 1LUKA 2PNBA 1NZLA 1AYCA 1D4TA 4F59A 1O4IA 1Y57A 3VS4A 3ZNIA 1BHHA 3HHMB 4U17A 3S8NA 4NWGA 1JYRA 1LKKA 1YVHA 3MXYA 1H9OA 3MAZA 3T04A 2MRJA 2C0IA 1AOTF 1O4MA 1BLKA 1LUIA 2AOBA 1O4NA 1ZFPE 3BUWB 4L1BB 1BKLA 3IN7A 3BUOB 2DVJA 1BKMA 5IBMA 4GL9E 2DLZA 2AUGA 1BHHB 2EKXA 2MK2A 3IMJA 2OZOA 3VS5A 1SHBA 2H5KA 4F5BA 1TCEA 2MQIA 3BUXB 1BFIA 1O4QA 2IZVA 1AYDA 1CWDL 3UF4A 3US4A 1R1SA 5HKYA 3OV1A 2GE9A 1AYAA 1QADA 1O4JA 1BFJA 1O4HA 3EACA 5GJIA 2EYVA 2CR4A 4GWFA 4FBNA 3VROA 1OO4A 4OHLA 1O4LA 1K9AA 2RVFA 1CSYA 5EEQA 3GXWA 2PLDA 4E68A 1GRIA 1KC2A 2HDXA 3CWGA 1O4CA 2LQNA 2DM0A 3VRPA 1BF5A 1TZEE 3C7IA 1D1ZA 2ETZA 4H34A 1A81A 5I6VA 3BUMB 5J3XA 2K79B 1AYBA 1FU5A 1BMBA 2QMSA 2HUWA 4ROJA 2EO6A 5DC4A 1Y1UA 2KK6A 1OPKA 4M4ZA 3S8OA 1A1BA 3VS7A 4FL2A 3UYOA 4GPLB 2BBUA 3VS3A 3PFVA 3CXLA 1XA6A 1O4BA 3VS1A 3KFJA 1I3ZA 2MC1A 2JYQA 1SPSA 2H8HA 1O48A 2EYZA 1JU5A 4K44A 1FU6A 2HMHA 1O4KA 1O4AA 1QCFA 4FL3A 2CBLA 2EU0A 4OHHA 5HKWA 3VS6A 5CDWA 1FYRA 1P13A 1AOUF 1CSZA 2C9WA 1A1EA 2EL8A 1A1CA 3VRRA 4XZ1A 1M61A 2L3TA 2LNWA 5EELA 3IMDA 2Y1NA 3PQZA 3PSJA 3GQIB 1RJAA 4A4CA 4LUEA 3VRNA 4OHDA 1FMKA 1KA7A 5DC9A 1NRVA 1RQQC 1O4EA 2CS0A 3VS2A 4A4BA 1BLJA 1A1AA 3TL0A 1NZVA 1D4WA 5AXIA 2XP1A 1KSWA 3TKZA 2EOBA 4TZIA 2EYYA 5HKZA 3N7YA 1UURA 1O47A 1R1QA 2RORA 4E93A 2CI9A 5KAZA 3OB1B 1A07A 3EAZA 5IBSA 2HCKA 3BKBA 1R1PA 4U1PA 4LUDA 2RSYA 2IUHA 1FBZA 1X0NA 1BM2A 1KA6A 2PLEA 2L6KA 2C0TA 3PSKA 1OO3A 1JYUA 1IS0A 1SHDA 1Z3KA 4F5AA 1HCTB 3HCKA 1AB2A 3S8LA 1A08A 3QWXX 3WA4A 1GHUA 1FBVA 1F1WA 1SHAA 1IJRA 2LNXA 5DC0B 4K2RA 3VGOA 4OHIA 5EHRA 4WWQA 1O4GA 2SHPA 1O4DA 1PICA 3VS0A 3S9KA 1BHFA 4JEGA 2Y1MA 3M7FA 4D8KA 1LUNA 2C0OA 5AULA 1O49A 1JWOA 5EG3B 5D0JA 1G83A 1O42A 2YU7A 3K2MA 1CJ1A 2SRCA 1MW4A 1YVLA 4QSYA 2EO3A 1LCJA 3OB2B 3CD3A 1O45A 3IN8A 1O41A 4JE4A 4NWFA 4DGPA 2ECDA 3VRYA 1LKLA 2DCRA 4K11A 3PJPA 5DF6A 1BG1A 1O46A 1UUSA 2VIFA 2IUGA 3CBLA 3NHNA 1MILA 1B47A 1A09A
chains in the Genus database with same CATH superfamily
3PLFB 4OHEA 4P9VA 2H46E 2KNOA 1LCKA 2MRKA 1QG1E 1RPYA 1SPRA 3BUNB 1O4RA 3HIZB 1O4OA 1O4PA 5EHPA 4EIHA 2IUIA 2CI8A 1F2FA 3VRQA 3N84A 3GXXA 4P9ZA 2YSXA 3OP0A 1SKJA 4XZ0A 2B3OA 2DX0A 1M27A 3OVEA 2OQ1A 2GSBA 2LQWA 2HDVA 1CWEA 3MXCA 1LUMA 2CIAA 1AD5A 2PNAA 3PS5A 2FCIA 5BO4A 2PTKA 1X27A 2AOAA 4X6SA 1O4FA 4H1OA 4DGXA 2ABLA 2RMXA 1FHSA 4K45A 3VRZA 3QWYA 3N8MA 5GJHA 1OPLA 1X6CA 4EY0A 2Y3AB 2L4KA 1O43A 2CRHA 2DLYA 4JGHA 1O44A 2K7AB 1JYQA 2FO0A 2LCTA 1WQUA 1HCSB 1LUKA 2PNBA 1NZLA 1AYCA 1D4TA 4F59A 1O4IA 1Y57A 3VS4A 3ZNIA 1BHHA 3HHMB 4U17A 3S8NA 4NWGA 1JYRA 3LYVA 1LKKA 1YVHA 3MXYA 1H9OA 3MAZA 3T04A 2MRJA 2C0IA 1AOTF 1O4MA 1BLKA 1LUIA 2AOBA 1O4NA 1ZFPE 3BUWB 4L1BB 1BKLA 3IN7A 3BUOB 2DVJA 1BKMA 5IBMA 4GL9E 2DLZA 2AUGA 1BHHB 2EKXA 2MK2A 3IMJA 2OZOA 3VS5A 1SHBA 2H5KA 4F5BA 1TCEA 2MQIA 3BUXB 1BFIA 1O4QA 2IZVA 1AYDA 1CWDL 3UF4A 3US4A 1R1SA 5HKYA 3OV1A 2GE9A 1AYAA 1QADA 1O4JA 1BFJA 1O4HA 3EACA 5GJIA 2EYVA 2CR4A 4GWFA 4FBNA 3VROA 1OO4A 4OHLA 1O4LA 1K9AA 2RVFA 1CSYA 5EEQA 3GXWA 2PLDA 4E68A 1GRIA 1KC2A 2HDXA 3CWGA 1O4CA 2LQNA 2DM0A 3VRPA 1BF5A 1TZEE 3C7IA 1D1ZA 2ETZA 4H34A 1A81A 5I6VA 3BUMB 5J3XA 2K79B 1AYBA 1FU5A 1BMBA 2QMSA 2HUWA 4ROJA 2EO6A 5DC4A 1Y1UA 2KK6A 1OPKA 4M4ZA 3S8OA 1A1BA 3VS7A 4FL2A 3UYOA 4GPLB 2BBUA 3VS3A 3PFVA 3CXLA 1XA6A 1O4BA 3VS1A 3KFJA 1I3ZA 2MC1A 2JYQA 3K2TA 1SPSA 2H8HA 1O48A 2EYZA 1JU5A 4K44A 1FU6A 2KGYA 2HMHA 1O4KA 1O4AA 1QCFA 2LRAA 4FL3A 2CBLA 2EU0A 4OHHA 5HKWA 3VS6A 5CDWA 1FYRA 1P13A 1AOUF 1CSZA 2C9WA 1A1EA 2EL8A 1A1CA 3VRRA 4XZ1A 1M61A 2L3TA 2LNWA 5EELA 3IMDA 2Y1NA 3PQZA 3PSJA 3GQIB 1RJAA 4A4CA 4LUEA 3VRNA 4OHDA 1FMKA 1KA7A 5DC9A 1NRVA 1RQQC 1O4EA 2CS0A 3VS2A 4A4BA 1BLJA 1A1AA 3TL0A 1NZVA 1D4WA 5AXIA 2XP1A 1KSWA 3TKZA 2EOBA 4TZIA 2EYYA 5HKZA 3N7YA 1UURA 1O47A 1R1QA 2RORA 4E93A 2CI9A 5KAZA 3OB1B 1A07A 3EAZA 5IBSA 2HCKA 3BKBA 1R1PA 4U1PA 4LUDA 2RSYA 2IUHA 1FBZA 1X0NA 1BM2A 1KA6A 2PLEA 2L6KA 2C0TA 3PSKA 1OO3A 1JYUA 1IS0A 1SHDA 1Z3KA 4F5AA 1HCTB 3HCKA 1AB2A 3S8LA 1A08A 3QWXX 3WA4A 1GHUA 1FBVA 1F1WA 1SHAA 1IJRA 2LNXA 5DC0B 4K2RA 3VGOA 4OHIA 5EHRA 4WWQA 1O4GA 2SHPA 1O4DA 1PICA 3VS0A 3S9KA 1BHFA 4JEGA 2Y1MA 3M7FA 4D8KA 1LUNA 2C0OA 5AULA 1O49A 1JWOA 5EG3B 5D0JA 1G83A 1O42A 2YU7A 3K2MA 1CJ1A 2SRCA 1MW4A 1YVLA 4QSYA 2EO3A 1LCJA 3OB2B 3CD3A 1O45A 3IN8A 1O41A 4JE4A 4NWFA 4DGPA 2ECDA 3VRYA 1LKLA 2DCRA 4K11A 3PJPA 5DF6A 1BG1A 1O46A 1UUSA 2VIFA 2IUGA 3CBLA 3NHNA 1MILA 1B47A 1A09A
chains in the Genus database with same CATH topology
3PLFB 4OHEA 4P9VA 2H46E 2KNOA 1LCKA 2MRKA 1QG1E 1RPYA 1SPRA 3BUNB 1O4RA 3HIZB 1O4OA 1O4PA 5EHPA 4EIHA 2IUIA 2CI8A 1F2FA 3VRQA 3N84A 3GXXA 4P9ZA 2YSXA 3OP0A 1SKJA 4XZ0A 2B3OA 2DX0A 1M27A 3OVEA 2OQ1A 2GSBA 2LQWA 2HDVA 1CWEA 3MXCA 1LUMA 2CIAA 1AD5A 2PNAA 3PS5A 2FCIA 5BO4A 2PTKA 1X27A 2AOAA 4X6SA 1O4FA 4H1OA 4DGXA 2ABLA 2RMXA 1FHSA 4K45A 3VRZA 3QWYA 3N8MA 5GJHA 1OPLA 1X6CA 4EY0A 2Y3AB 2L4KA 1O43A 2CRHA 2DLYA 4JGHA 1O44A 2K7AB 1JYQA 2FO0A 2LCTA 1WQUA 1HCSB 1LUKA 2PNBA 1NZLA 1AYCA 1D4TA 4F59A 1O4IA 1Y57A 3VS4A 3ZNIA 1BHHA 3HHMB 4U17A 3S8NA 4NWGA 1JYRA 1LKKA 1YVHA 3MXYA 1H9OA 3MAZA 3T04A 2MRJA 2C0IA 1AOTF 1O4MA 1BLKA 1LUIA 2AOBA 1O4NA 1ZFPE 3BUWB 4L1BB 1BKLA 3IN7A 3BUOB 2DVJA 1BKMA 5IBMA 4GL9E 2DLZA 2AUGA 1BHHB 2EKXA 2MK2A 3IMJA 2OZOA 3VS5A 1SHBA 2H5KA 4F5BA 1TCEA 2MQIA 3BUXB 1BFIA 1O4QA 2IZVA 1AYDA 1CWDL 3UF4A 3US4A 1R1SA 5HKYA 3OV1A 2GE9A 1AYAA 1QADA 1O4JA 1BFJA 1O4HA 3EACA 5GJIA 2EYVA 2CR4A 4GWFA 4FBNA 3VROA 1OO4A 4OHLA 1O4LA 1K9AA 2RVFA 1CSYA 5EEQA 3GXWA 2PLDA 4E68A 1GRIA 1KC2A 2HDXA 3CWGA 1O4CA 2LQNA 2DM0A 3VRPA 1BF5A 1TZEE 3C7IA 1D1ZA 2ETZA 4H34A 1A81A 5I6VA 3BUMB 5J3XA 2K79B 1AYBA 1FU5A 1BMBA 2QMSA 2HUWA 4ROJA 2EO6A 5DC4A 1Y1UA 2KK6A 1OPKA 4M4ZA 3S8OA 1A1BA 3VS7A 4FL2A 3UYOA 4GPLB 2BBUA 3VS3A 3PFVA 3CXLA 1XA6A 1O4BA 3VS1A 3KFJA 1I3ZA 2MC1A 2JYQA 1SPSA 2H8HA 1O48A 2EYZA 1JU5A 4K44A 1FU6A 2HMHA 1O4KA 1O4AA 1QCFA 4FL3A 2CBLA 2EU0A 4OHHA 5HKWA 3VS6A 5CDWA 1FYRA 1P13A 1AOUF 1CSZA 2C9WA 1A1EA 2EL8A 1A1CA 3VRRA 4XZ1A 1M61A 2L3TA 2LNWA 5EELA 3IMDA 2Y1NA 3PQZA 3PSJA 3GQIB 1RJAA 4A4CA 4LUEA 3VRNA 4OHDA 1FMKA 1KA7A 5DC9A 1NRVA 1RQQC 1O4EA 2CS0A 3VS2A 4A4BA 1BLJA 1A1AA 3TL0A 1NZVA 1D4WA 5AXIA 2XP1A 1KSWA 3TKZA 2EOBA 4TZIA 2EYYA 5HKZA 3N7YA 1UURA 1O47A 1R1QA 2RORA 4E93A 2CI9A 5KAZA 3OB1B 1A07A 3EAZA 5IBSA 2HCKA 3BKBA 1R1PA 4U1PA 4LUDA 2RSYA 2IUHA 1FBZA 1X0NA 1BM2A 1KA6A 2PLEA 2L6KA 2C0TA 3PSKA 1OO3A 1JYUA 1IS0A 1SHDA 1Z3KA 4F5AA 1HCTB 3HCKA 1AB2A 3S8LA 1A08A 3QWXX 3WA4A 1GHUA 1FBVA 1F1WA 1SHAA 1IJRA 2LNXA 5DC0B 4K2RA 3VGOA 4OHIA 5EHRA 4WWQA 1O4GA 2SHPA 1O4DA 1PICA 3VS0A 3S9KA 1BHFA 4JEGA 2Y1MA 3M7FA 4D8KA 1LUNA 2C0OA 5AULA 1O49A 1JWOA 5EG3B 5D0JA 1G83A 1O42A 2YU7A 3K2MA 1CJ1A 2SRCA 1MW4A 1YVLA 4QSYA 2EO3A 1LCJA 3OB2B 3CD3A 1O45A 3IN8A 1O41A 4JE4A 4NWFA 4DGPA 2ECDA 3VRYA 1LKLA 2DCRA 4K11A 3PJPA 5DF6A 1BG1A 1O46A 1UUSA 2VIFA 2IUGA 3CBLA 3NHNA 1MILA 1B47A 1A09A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PLF B;  4OHE A;  4P9V A;  2H46 E;  2KNO A;  1LCK A;  2MRK A;  1QG1 E;  1RPY A;  1SPR A;  3BUN B;  1O4R A;  3HIZ B;  1O4O A;  1O4P A;  5EHP A;  4EIH A;  2IUI A;  2CI8 A;  1F2F A;  3VRQ A;  3N84 A;  3GXX A;  4P9Z A;  2YSX A;  3OP0 A;  1SKJ A;  4XZ0 A;  2B3O A;  2DX0 A;  1M27 A;  3OVE A;  2OQ1 A;  2GSB A;  2LQW A;  2HDV A;  1CWE A;  3MXC A;  1LUM A;  2CIA A;  1AD5 A;  2PNA A;  3PS5 A;  2FCI A;  5BO4 A;  2PTK A;  1X27 A;  2AOA A;  4X6S A;  1O4F A;  4H1O A;  4DGX A;  2ABL A;  2RMX A;  1FHS A;  4K45 A;  3VRZ A;  3QWY A;  3N8M A;  5GJH A;  1OPL A;  1X6C A;  4EY0 A;  2Y3A B;  2L4K A;  1O43 A;  2CRH A;  2DLY A;  4JGH A;  1O44 A;  2K7A B;  1JYQ A;  2FO0 A;  2LCT A;  1WQU A;  1HCS B;  1LUK A;  2PNB A;  1NZL A;  1AYC A;  1D4T A;  4F59 A;  1O4I A;  1Y57 A;  3VS4 A;  3ZNI A;  1BHH A;  3HHM B;  4U17 A;  3S8N A;  4NWG A;  1JYR A;  1LKK A;  1YVH A;  3MXY A;  1H9O A;  3MAZ A;  3T04 A;  2MRJ A;  2C0I A;  1AOT F;  1O4M A;  1BLK A;  1LUI A;  2AOB A;  1O4N A;  1ZFP E;  3BUW B;  4L1B B;  1BKL A;  3IN7 A;  3BUO B;  2DVJ A;  1BKM A;  5IBM A;  4GL9 E;  2DLZ A;  2AUG A;  1BHH B;  2EKX A;  2MK2 A;  3IMJ A;  2OZO A;  3VS5 A;  1SHB A;  2H5K A;  4F5B A;  1TCE A;  2MQI A;  3BUX B;  1BFI A;  1O4Q A;  2IZV A;  1AYD A;  1CWD L;  3UF4 A;  3US4 A;  1R1S A;  5HKY A;  3OV1 A;  2GE9 A;  1AYA A;  1QAD A;  1O4J A;  1BFJ A;  1O4H A;  3EAC A;  5GJI A;  2EYV A;  2CR4 A;  4GWF A;  4FBN A;  3VRO A;  1OO4 A;  4OHL A;  1O4L A;  1K9A A;  2RVF A;  1CSY A;  5EEQ A;  3GXW A;  2PLD A;  4E68 A;  1GRI A;  1KC2 A;  2HDX A;  3CWG A;  1O4C A;  2LQN A;  2DM0 A;  3VRP A;  1BF5 A;  1TZE E;  3C7I A;  1D1Z A;  2ETZ A;  4H34 A;  1A81 A;  5I6V A;  3BUM B;  5J3X A;  2K79 B;  1AYB A;  1FU5 A;  1BMB A;  2QMS A;  2HUW A;  4ROJ A;  2EO6 A;  5DC4 A;  1Y1U A;  2KK6 A;  1OPK A;  4M4Z A;  3S8O A;  1A1B A;  3VS7 A;  4FL2 A;  3UYO A;  4GPL B;  2BBU A;  3VS3 A;  3PFV A;  3CXL A;  1XA6 A;  1O4B A;  3VS1 A;  3KFJ A;  1I3Z A;  2MC1 A;  2JYQ A;  1SPS A;  2H8H A;  1O48 A;  2EYZ A;  1JU5 A;  4K44 A;  1FU6 A;  2HMH A;  1O4K A;  1O4A A;  1QCF A;  4FL3 A;  2CBL A;  2EU0 A;  4OHH A;  5HKW A;  3VS6 A;  5CDW A;  1FYR A;  1P13 A;  1AOU F;  1CSZ A;  2C9W A;  1A1E A;  2EL8 A;  1A1C A;  3VRR A;  4XZ1 A;  1M61 A;  2L3T A;  2LNW A;  5EEL A;  3IMD A;  2Y1N A;  3PQZ A;  3PSJ A;  3GQI B;  1RJA A;  4A4C A;  4LUE A;  3VRN A;  4OHD A;  1FMK A;  1KA7 A;  5DC9 A;  1NRV A;  1RQQ C;  1O4E A;  2CS0 A;  3VS2 A;  4A4B A;  1BLJ A;  1A1A A;  3TL0 A;  1NZV A;  1D4W A;  5AXI A;  2XP1 A;  1KSW A;  3TKZ A;  2EOB A;  4TZI A;  2EYY A;  5HKZ A;  3N7Y A;  1UUR A;  1O47 A;  1R1Q A;  2ROR A;  4E93 A;  2CI9 A;  5KAZ A;  3OB1 B;  1A07 A;  3EAZ A;  5IBS A;  2HCK A;  3BKB A;  1R1P A;  4U1P A;  4LUD A;  2RSY A;  2IUH A;  1FBZ A;  1X0N A;  1BM2 A;  1KA6 A;  2PLE A;  2L6K A;  2C0T A;  3PSK A;  1OO3 A;  1JYU A;  1IS0 A;  1SHD A;  1Z3K A;  4F5A A;  1HCT B;  3HCK A;  1AB2 A;  3S8L A;  1A08 A;  3QWX X;  3WA4 A;  1GHU A;  1FBV A;  1F1W A;  1SHA A;  1IJR A;  2LNX A;  5DC0 B;  4K2R A;  3VGO A;  4OHI A;  5EHR A;  4WWQ A;  1O4G A;  2SHP A;  1O4D A;  1PIC A;  3VS0 A;  3S9K A;  1BHF A;  4JEG A;  2Y1M A;  3M7F A;  4D8K A;  1LUN A;  2C0O A;  5AUL A;  1O49 A;  1JWO A;  5EG3 B;  5D0J A;  1G83 A;  1O42 A;  2YU7 A;  3K2M A;  1CJ1 A;  2SRC A;  1MW4 A;  1YVL A;  4QSY A;  2EO3 A;  1LCJ A;  3OB2 B;  3CD3 A;  1O45 A;  3IN8 A;  1O41 A;  4JE4 A;  4NWF A;  4DGP A;  2ECD A;  3VRY A;  1LKL A;  2DCR A;  4K11 A;  3PJP A;  5DF6 A;  1BG1 A;  1O46 A;  1UUS A;  2VIF A;  2IUG A;  3CBL A;  3NHN A;  1MIL A;  1B47 A;  1A09 A; 
#chains in the Genus database with same CATH topology
 3PLF B;  4OHE A;  4P9V A;  2H46 E;  2KNO A;  1LCK A;  2MRK A;  1QG1 E;  1RPY A;  1SPR A;  3BUN B;  1O4R A;  3HIZ B;  1O4O A;  1O4P A;  5EHP A;  4EIH A;  2IUI A;  2CI8 A;  1F2F A;  3VRQ A;  3N84 A;  3GXX A;  4P9Z A;  2YSX A;  3OP0 A;  1SKJ A;  4XZ0 A;  2B3O A;  2DX0 A;  1M27 A;  3OVE A;  2OQ1 A;  2GSB A;  2LQW A;  2HDV A;  1CWE A;  3MXC A;  1LUM A;  2CIA A;  1AD5 A;  2PNA A;  3PS5 A;  2FCI A;  5BO4 A;  2PTK A;  1X27 A;  2AOA A;  4X6S A;  1O4F A;  4H1O A;  4DGX A;  2ABL A;  2RMX A;  1FHS A;  4K45 A;  3VRZ A;  3QWY A;  3N8M A;  5GJH A;  1OPL A;  1X6C A;  4EY0 A;  2Y3A B;  2L4K A;  1O43 A;  2CRH A;  2DLY A;  4JGH A;  1O44 A;  2K7A B;  1JYQ A;  2FO0 A;  2LCT A;  1WQU A;  1HCS B;  1LUK A;  2PNB A;  1NZL A;  1AYC A;  1D4T A;  4F59 A;  1O4I A;  1Y57 A;  3VS4 A;  3ZNI A;  1BHH A;  3HHM B;  4U17 A;  3S8N A;  4NWG A;  1JYR A;  3LYV A;  1LKK A;  1YVH A;  3MXY A;  1H9O A;  3MAZ A;  3T04 A;  2MRJ A;  2C0I A;  1AOT F;  1O4M A;  1BLK A;  1LUI A;  2AOB A;  1O4N A;  1ZFP E;  3BUW B;  4L1B B;  1BKL A;  3IN7 A;  3BUO B;  2DVJ A;  1BKM A;  5IBM A;  4GL9 E;  2DLZ A;  2AUG A;  1BHH B;  2EKX A;  2MK2 A;  3IMJ A;  2OZO A;  3VS5 A;  1SHB A;  2H5K A;  4F5B A;  1TCE A;  2MQI A;  3BUX B;  1BFI A;  1O4Q A;  2IZV A;  1AYD A;  1CWD L;  3UF4 A;  3US4 A;  1R1S A;  5HKY A;  3OV1 A;  2GE9 A;  1AYA A;  1QAD A;  1O4J A;  1BFJ A;  1O4H A;  3EAC A;  5GJI A;  2EYV A;  2CR4 A;  4GWF A;  4FBN A;  3VRO A;  1OO4 A;  4OHL A;  1O4L A;  1K9A A;  2RVF A;  1CSY A;  5EEQ A;  3GXW A;  2PLD A;  4E68 A;  1GRI A;  1KC2 A;  2HDX A;  3CWG A;  1O4C A;  2LQN A;  2DM0 A;  3VRP A;  1BF5 A;  1TZE E;  3C7I A;  1D1Z A;  2ETZ A;  4H34 A;  1A81 A;  5I6V A;  3BUM B;  5J3X A;  2K79 B;  1AYB A;  1FU5 A;  1BMB A;  2QMS A;  2HUW A;  4ROJ A;  2EO6 A;  5DC4 A;  1Y1U A;  2KK6 A;  1OPK A;  4M4Z A;  3S8O A;  1A1B A;  3VS7 A;  4FL2 A;  3UYO A;  4GPL B;  2BBU A;  3VS3 A;  3PFV A;  3CXL A;  1XA6 A;  1O4B A;  3VS1 A;  3KFJ A;  1I3Z A;  2MC1 A;  2JYQ A;  3K2T A;  1SPS A;  2H8H A;  1O48 A;  2EYZ A;  1JU5 A;  4K44 A;  1FU6 A;  2KGY A;  2HMH A;  1O4K A;  1O4A A;  1QCF A;  2LRA A;  4FL3 A;  2CBL A;  2EU0 A;  4OHH A;  5HKW A;  3VS6 A;  5CDW A;  1FYR A;  1P13 A;  1AOU F;  1CSZ A;  2C9W A;  1A1E A;  2EL8 A;  1A1C A;  3VRR A;  4XZ1 A;  1M61 A;  2L3T A;  2LNW A;  5EEL A;  3IMD A;  2Y1N A;  3PQZ A;  3PSJ A;  3GQI B;  1RJA A;  4A4C A;  4LUE A;  3VRN A;  4OHD A;  1FMK A;  1KA7 A;  5DC9 A;  1NRV A;  1RQQ C;  1O4E A;  2CS0 A;  3VS2 A;  4A4B A;  1BLJ A;  1A1A A;  3TL0 A;  1NZV A;  1D4W A;  5AXI A;  2XP1 A;  1KSW A;  3TKZ A;  2EOB A;  4TZI A;  2EYY A;  5HKZ A;  3N7Y A;  1UUR A;  1O47 A;  1R1Q A;  2ROR A;  4E93 A;  2CI9 A;  5KAZ A;  3OB1 B;  1A07 A;  3EAZ A;  5IBS A;  2HCK A;  3BKB A;  1R1P A;  4U1P A;  4LUD A;  2RSY A;  2IUH A;  1FBZ A;  1X0N A;  1BM2 A;  1KA6 A;  2PLE A;  2L6K A;  2C0T A;  3PSK A;  1OO3 A;  1JYU A;  1IS0 A;  1SHD A;  1Z3K A;  4F5A A;  1HCT B;  3HCK A;  1AB2 A;  3S8L A;  1A08 A;  3QWX X;  3WA4 A;  1GHU A;  1FBV A;  1F1W A;  1SHA A;  1IJR A;  2LNX A;  5DC0 B;  4K2R A;  3VGO A;  4OHI A;  5EHR A;  4WWQ A;  1O4G A;  2SHP A;  1O4D A;  1PIC A;  3VS0 A;  3S9K A;  1BHF A;  4JEG A;  2Y1M A;  3M7F A;  4D8K A;  1LUN A;  2C0O A;  5AUL A;  1O49 A;  1JWO A;  5EG3 B;  5D0J A;  1G83 A;  1O42 A;  2YU7 A;  3K2M A;  1CJ1 A;  2SRC A;  1MW4 A;  1YVL A;  4QSY A;  2EO3 A;  1LCJ A;  3OB2 B;  3CD3 A;  1O45 A;  3IN8 A;  1O41 A;  4JE4 A;  4NWF A;  4DGP A;  2ECD A;  3VRY A;  1LKL A;  2DCR A;  4K11 A;  3PJP A;  5DF6 A;  1BG1 A;  1O46 A;  1UUS A;  2VIF A;  2IUG A;  3CBL A;  3NHN A;  1MIL A;  1B47 A;  1A09 A; 
#chains in the Genus database with same CATH homology
 3PLF B;  4OHE A;  4P9V A;  2H46 E;  2KNO A;  1LCK A;  2MRK A;  1QG1 E;  1RPY A;  1SPR A;  3BUN B;  1O4R A;  3HIZ B;  1O4O A;  1O4P A;  5EHP A;  4EIH A;  2IUI A;  2CI8 A;  1F2F A;  3VRQ A;  3N84 A;  3GXX A;  4P9Z A;  2YSX A;  3OP0 A;  1SKJ A;  4XZ0 A;  2B3O A;  2DX0 A;  1M27 A;  3OVE A;  2OQ1 A;  2GSB A;  2LQW A;  2HDV A;  1CWE A;  3MXC A;  1LUM A;  2CIA A;  1AD5 A;  2PNA A;  3PS5 A;  2FCI A;  5BO4 A;  2PTK A;  1X27 A;  2AOA A;  4X6S A;  1O4F A;  4H1O A;  4DGX A;  2ABL A;  2RMX A;  1FHS A;  4K45 A;  3VRZ A;  3QWY A;  3N8M A;  5GJH A;  1OPL A;  1X6C A;  4EY0 A;  2Y3A B;  2L4K A;  1O43 A;  2CRH A;  2DLY A;  4JGH A;  1O44 A;  2K7A B;  1JYQ A;  2FO0 A;  2LCT A;  1WQU A;  1HCS B;  1LUK A;  2PNB A;  1NZL A;  1AYC A;  1D4T A;  4F59 A;  1O4I A;  1Y57 A;  3VS4 A;  3ZNI A;  1BHH A;  3HHM B;  4U17 A;  3S8N A;  4NWG A;  1JYR A;  1LKK A;  1YVH A;  3MXY A;  1H9O A;  3MAZ A;  3T04 A;  2MRJ A;  2C0I A;  1AOT F;  1O4M A;  1BLK A;  1LUI A;  2AOB A;  1O4N A;  1ZFP E;  3BUW B;  4L1B B;  1BKL A;  3IN7 A;  3BUO B;  2DVJ A;  1BKM A;  5IBM A;  4GL9 E;  2DLZ A;  2AUG A;  1BHH B;  2EKX A;  2MK2 A;  3IMJ A;  2OZO A;  3VS5 A;  1SHB A;  2H5K A;  4F5B A;  1TCE A;  2MQI A;  3BUX B;  1BFI A;  1O4Q A;  2IZV A;  1AYD A;  1CWD L;  3UF4 A;  3US4 A;  1R1S A;  5HKY A;  3OV1 A;  2GE9 A;  1AYA A;  1QAD A;  1O4J A;  1BFJ A;  1O4H A;  3EAC A;  5GJI A;  2EYV A;  2CR4 A;  4GWF A;  4FBN A;  3VRO A;  1OO4 A;  4OHL A;  1O4L A;  1K9A A;  2RVF A;  1CSY A;  5EEQ A;  3GXW A;  2PLD A;  4E68 A;  1GRI A;  1KC2 A;  2HDX A;  3CWG A;  1O4C A;  2LQN A;  2DM0 A;  3VRP A;  1BF5 A;  1TZE E;  3C7I A;  1D1Z A;  2ETZ A;  4H34 A;  1A81 A;  5I6V A;  3BUM B;  5J3X A;  2K79 B;  1AYB A;  1FU5 A;  1BMB A;  2QMS A;  2HUW A;  4ROJ A;  2EO6 A;  5DC4 A;  1Y1U A;  2KK6 A;  1OPK A;  4M4Z A;  3S8O A;  1A1B A;  3VS7 A;  4FL2 A;  3UYO A;  4GPL B;  2BBU A;  3VS3 A;  3PFV A;  3CXL A;  1XA6 A;  1O4B A;  3VS1 A;  3KFJ A;  1I3Z A;  2MC1 A;  2JYQ A;  1SPS A;  2H8H A;  1O48 A;  2EYZ A;  1JU5 A;  4K44 A;  1FU6 A;  2HMH A;  1O4K A;  1O4A A;  1QCF A;  4FL3 A;  2CBL A;  2EU0 A;  4OHH A;  5HKW A;  3VS6 A;  5CDW A;  1FYR A;  1P13 A;  1AOU F;  1CSZ A;  2C9W A;  1A1E A;  2EL8 A;  1A1C A;  3VRR A;  4XZ1 A;  1M61 A;  2L3T A;  2LNW A;  5EEL A;  3IMD A;  2Y1N A;  3PQZ A;  3PSJ A;  3GQI B;  1RJA A;  4A4C A;  4LUE A;  3VRN A;  4OHD A;  1FMK A;  1KA7 A;  5DC9 A;  1NRV A;  1RQQ C;  1O4E A;  2CS0 A;  3VS2 A;  4A4B A;  1BLJ A;  1A1A A;  3TL0 A;  1NZV A;  1D4W A;  5AXI A;  2XP1 A;  1KSW A;  3TKZ A;  2EOB A;  4TZI A;  2EYY A;  5HKZ A;  3N7Y A;  1UUR A;  1O47 A;  1R1Q A;  2ROR A;  4E93 A;  2CI9 A;  5KAZ A;  3OB1 B;  1A07 A;  3EAZ A;  5IBS A;  2HCK A;  3BKB A;  1R1P A;  4U1P A;  4LUD A;  2RSY A;  2IUH A;  1FBZ A;  1X0N A;  1BM2 A;  1KA6 A;  2PLE A;  2L6K A;  2C0T A;  3PSK A;  1OO3 A;  1JYU A;  1IS0 A;  1SHD A;  1Z3K A;  4F5A A;  1HCT B;  3HCK A;  1AB2 A;  3S8L A;  1A08 A;  3QWX X;  3WA4 A;  1GHU A;  1FBV A;  1F1W A;  1SHA A;  1IJR A;  2LNX A;  5DC0 B;  4K2R A;  3VGO A;  4OHI A;  5EHR A;  4WWQ A;  1O4G A;  2SHP A;  1O4D A;  1PIC A;  3VS0 A;  3S9K A;  1BHF A;  4JEG A;  2Y1M A;  3M7F A;  4D8K A;  1LUN A;  2C0O A;  5AUL A;  1O49 A;  1JWO A;  5EG3 B;  5D0J A;  1G83 A;  1O42 A;  2YU7 A;  3K2M A;  1CJ1 A;  2SRC A;  1MW4 A;  1YVL A;  4QSY A;  2EO3 A;  1LCJ A;  3OB2 B;  3CD3 A;  1O45 A;  3IN8 A;  1O41 A;  4JE4 A;  4NWF A;  4DGP A;  2ECD A;  3VRY A;  1LKL A;  2DCR A;  4K11 A;  3PJP A;  5DF6 A;  1BG1 A;  1O46 A;  1UUS A;  2VIF A;  2IUG A;  3CBL A;  3NHN A;  1MIL A;  1B47 A;  1A09 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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