3MXYA

Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications.
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
101
structure length
101
Chain Sequence
GSHMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 22
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2010-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3mxyA00
2ECDA 5KAZA 1G83A 1LUKA 1SPRA 2ABLA 1OPKA 1O4RA 4E68A 3S9KA 1AOUF 5DC9A 5DC0B 3GXXA 2EO6A 2IZVA 2H5KA 4L1BB 5CDWA 1O4GA 3HCKA 4OHLA 1AB2A 2PLEA 3N7YA 2DX0A 1KC2A 3VGOA 3CWGA 2YU7A 1O49A 2DVJA 1O4BA 2XP1A 3TL0A 1LCJA 2H8HA 1IS0A 3S8LA 5HKZA 4A4BA 1O4JA 2GE9A 1O41A 2MRKA 4FL2A 2BBUA 5HKYA 2EYVA 1R1PA 3HIZB 3K2MA 1A07A 1FMKA 1FHSA 4F5AA 1BHHA 1M61A 1PICA 5IBSA 1LKKA 1O42A 2B3OA 1K9AA 4H1OA 1BG1A 3IN7A 1RJAA 2KK6A 3OB1B 4K45A 3OB2B 3US4A 3CXLA 3VS1A 3KFJA 1HCSB 1AYCA 3BUMB 1UUSA 2HUWA 2C9WA 2OQ1A 1O4MA 1MILA 2CBLA 1P13A 2KNOA 2L4KA 5GJIA 2VIFA 3MXYA 3MAZA 3PJPA 4OHIA 1SKJA 1D1ZA 2DLZA 1O43A 1BFIA 1OO4A 3TKZA 2IUIA 4M4ZA 2CIAA 3IMJA 5DC4A 4TZIA 1R1SA 3UF4A 2AOAA 2OZOA 1OPLA 1O4OA 1QADA 4WWQA 1NZLA 1O48A 2PTKA 1TZEE 1JYUA 4H34A 1NZVA 1O4PA 3OV1A 1A1BA 1A81A 2EOBA 1O45A 3VS5A 2HCKA 1I3ZA 2IUGA 4OHDA 1WQUA 1AD5A 1FBVA 1YVHA 4OHEA 1RQQC 1JU5A 4E93A 4EY0A 1A1CA 2GSBA 2DLYA 1O4IA 3N84A 4FL3A 4XZ0A 2IUHA 1AYDA 1CWDL 2HMHA 2MQIA 1YVLA 4D8KA 2Y3AB 1TCEA 1SHDA 3CBLA 3VS6A 2SRCA 1OO3A 4U1PA 1O4NA 1RPYA 1ZFPE 1A08A 4F59A 2EYYA 1D4TA 4K2RA 1KSWA 3BUNB 1O4AA 2MC1A 1FYRA 1M27A 4F5BA 2LCTA 5J3XA 3BKBA 2FO0A 1SHAA 1O4KA 1F1WA 3OP0A 3ZNIA 1UURA 2LNXA 2Y1NA 3BUOB 3PFVA 4LUEA 3VS7A 2L3TA 3EAZA 1LKLA 3VRNA 1SHBA 3VRRA 1X0NA 1B47A 2EL8A 2CS0A 5EEQA 2Y1MA 5EG3B 4NWFA 1QCFA 3IN8A 5DF6A 2EU0A 4P9VA 2HDVA 4A4CA 4K11A 5HKWA 1FBZA 1LUNA 4GPLB 1X27A 1O4HA 3PS5A 2EYZA 2LQNA 1SPSA 3PQZA 3VS0A 2PNAA 1D4WA 3PSJA 1Y1UA 1LCKA 4JE4A 3VROA 3S8NA 1GHUA 4K44A 2QMSA 3VRPA 4XZ1A 5EHRA 1BM2A 1MW4A 1QG1E 1A1AA 4DGPA 1BHHB 3QWYA 5I6VA 1BFJA 1BHFA 2C0TA 4ROJA 1F2FA 2AOBA 3NHNA 3IMDA 1A09A 2CI9A 1KA7A 1Z3KA 3M7FA 2CRHA 3QWXX 5GJHA 4FBNA 4LUDA 1NRVA 3S8OA 4GWFA 5EELA 3VS2A 1HCTB 3VS3A 2K79B 2HDXA 3GQIB 5IBMA 4X6SA 2RVFA 1FU6A 1BF5A 2DCRA 4QSYA 3VRZA 2H46E 3HHMB 1JWOA 2MRJA 2SHPA 2PNBA 1FU5A 3N8MA 1O4DA 1IJRA 5EHPA 1AOTF 2C0IA 1X6CA 1CSYA 1O44A 1JYRA 2ETZA 4U17A 4OHHA 1O4QA 5AXIA 5AULA 3MXCA 1A1EA 4JEGA 2RMXA 1XA6A 3T04A 1KA6A 1BLJA 4JGHA 2PLDA 2K7AB 1O47A 3WA4A 2LNWA 2DM0A 3BUXB 1O4CA 1BKMA 4GL9E 1CJ1A 1LUMA 1O46A 2L6KA 5D0JA 1O4FA 2RSYA 2MK2A 2FCIA 2JYQA 1O4LA 4P9ZA 4NWGA 1LUIA 1Y57A 3VRYA 2CI8A 4EIHA 1H9OA 3PLFB 1CWEA 4DGXA 2C0OA 1O4EA 1AYAA 3EACA 2AUGA 3CD3A 2LQWA 1BMBA 2EKXA 1BLKA 3C7IA 5BO4A 3OVEA 3PSKA 1JYQA 2EO3A 3GXWA 3BUWB 1R1QA 1AYBA 2CR4A 2RORA 3VRQA 3UYOA 1GRIA 2YSXA 1CSZA 1BKLA 3VS4A
chains in the Genus database with same CATH superfamily
2ECDA 5KAZA 1G83A 1LUKA 1SPRA 2ABLA 1OPKA 1O4RA 4E68A 3S9KA 1AOUF 5DC9A 5DC0B 3GXXA 2EO6A 2IZVA 2H5KA 4L1BB 5CDWA 1O4GA 3HCKA 4OHLA 1AB2A 2PLEA 3N7YA 2DX0A 1KC2A 3VGOA 3CWGA 2YU7A 1O49A 2DVJA 1O4BA 2XP1A 3TL0A 1LCJA 2H8HA 1IS0A 3S8LA 5HKZA 4A4BA 1O4JA 2GE9A 1O41A 2MRKA 4FL2A 2BBUA 5HKYA 2EYVA 1R1PA 3HIZB 3K2MA 1A07A 1FMKA 1FHSA 4F5AA 1BHHA 1M61A 1PICA 5IBSA 1LKKA 1O42A 2B3OA 1K9AA 4H1OA 1BG1A 3IN7A 1RJAA 2KK6A 3OB1B 4K45A 3OB2B 3US4A 3CXLA 3VS1A 3KFJA 1HCSB 1AYCA 3BUMB 1UUSA 2HUWA 2C9WA 2OQ1A 1O4MA 1MILA 2CBLA 1P13A 2KNOA 2L4KA 5GJIA 2VIFA 3MXYA 3MAZA 3PJPA 4OHIA 1SKJA 1D1ZA 2DLZA 1O43A 1BFIA 1OO4A 3TKZA 2IUIA 4M4ZA 2CIAA 3IMJA 5DC4A 4TZIA 1R1SA 3UF4A 2AOAA 2OZOA 1OPLA 1O4OA 1QADA 4WWQA 1NZLA 1O48A 2PTKA 1TZEE 1JYUA 4H34A 1NZVA 1O4PA 3OV1A 1A1BA 1A81A 2EOBA 1O45A 3VS5A 2HCKA 1I3ZA 2IUGA 4OHDA 1WQUA 1AD5A 3K2TA 1FBVA 1YVHA 4OHEA 1RQQC 1JU5A 4E93A 4EY0A 1A1CA 2GSBA 2DLYA 1O4IA 3N84A 2LRAA 4FL3A 4XZ0A 2IUHA 1AYDA 1CWDL 2HMHA 2MQIA 1YVLA 4D8KA 2Y3AB 1TCEA 1SHDA 3CBLA 3VS6A 2SRCA 1OO3A 4U1PA 1O4NA 1RPYA 1ZFPE 1A08A 4F59A 2EYYA 1D4TA 4K2RA 1KSWA 3BUNB 1O4AA 2MC1A 1FYRA 1M27A 4F5BA 2LCTA 5J3XA 3BKBA 2FO0A 1SHAA 1O4KA 1F1WA 3OP0A 3ZNIA 1UURA 2LNXA 2Y1NA 3BUOB 3PFVA 4LUEA 3VS7A 2L3TA 3EAZA 1LKLA 3VRNA 1SHBA 3VRRA 1X0NA 1B47A 2EL8A 2CS0A 5EEQA 2Y1MA 5EG3B 4NWFA 1QCFA 3IN8A 5DF6A 2EU0A 4P9VA 2HDVA 4A4CA 4K11A 5HKWA 1FBZA 1LUNA 4GPLB 1X27A 1O4HA 3PS5A 2EYZA 2LQNA 1SPSA 3PQZA 3VS0A 2PNAA 1D4WA 3PSJA 1Y1UA 1LCKA 2KGYA 4JE4A 3VROA 3S8NA 1GHUA 4K44A 2QMSA 3VRPA 4XZ1A 5EHRA 1BM2A 1MW4A 1QG1E 1A1AA 4DGPA 1BHHB 3QWYA 5I6VA 1BFJA 1BHFA 2C0TA 4ROJA 1F2FA 2AOBA 3NHNA 3IMDA 1A09A 2CI9A 1KA7A 1Z3KA 3M7FA 2CRHA 3QWXX 5GJHA 4FBNA 4LUDA 1NRVA 3S8OA 4GWFA 5EELA 3VS2A 1HCTB 3VS3A 2K79B 2HDXA 3GQIB 5IBMA 4X6SA 2RVFA 1FU6A 1BF5A 2DCRA 4QSYA 3VRZA 2H46E 3HHMB 1JWOA 2MRJA 2SHPA 2PNBA 1FU5A 3N8MA 1O4DA 1IJRA 5EHPA 1AOTF 2C0IA 1X6CA 1CSYA 1O44A 1JYRA 2ETZA 4U17A 4OHHA 1O4QA 5AXIA 5AULA 3MXCA 1A1EA 4JEGA 2RMXA 1XA6A 3T04A 1KA6A 1BLJA 4JGHA 2PLDA 2K7AB 1O47A 3WA4A 2LNWA 2DM0A 3BUXB 1O4CA 1BKMA 4GL9E 1CJ1A 1LUMA 1O46A 2L6KA 5D0JA 1O4FA 2RSYA 2MK2A 2FCIA 2JYQA 1O4LA 4P9ZA 4NWGA 1LUIA 1Y57A 3VRYA 2CI8A 4EIHA 1H9OA 3PLFB 1CWEA 4DGXA 2C0OA 1O4EA 1AYAA 3EACA 2AUGA 3CD3A 2LQWA 1BMBA 2EKXA 1BLKA 3C7IA 5BO4A 3OVEA 3LYVA 3PSKA 1JYQA 2EO3A 3GXWA 3BUWB 1R1QA 1AYBA 2CR4A 2RORA 3VRQA 3UYOA 1GRIA 2YSXA 1CSZA 1BKLA 3VS4A
chains in the Genus database with same CATH topology
2ECDA 5KAZA 1G83A 1LUKA 1SPRA 2ABLA 1OPKA 1O4RA 4E68A 3S9KA 1AOUF 5DC9A 5DC0B 3GXXA 2EO6A 2IZVA 2H5KA 4L1BB 5CDWA 1O4GA 3HCKA 4OHLA 1AB2A 2PLEA 3N7YA 2DX0A 1KC2A 3VGOA 3CWGA 2YU7A 1O49A 2DVJA 1O4BA 2XP1A 3TL0A 1LCJA 2H8HA 1IS0A 3S8LA 5HKZA 4A4BA 1O4JA 2GE9A 1O41A 2MRKA 4FL2A 2BBUA 5HKYA 2EYVA 1R1PA 3HIZB 3K2MA 1A07A 1FMKA 1FHSA 4F5AA 1BHHA 1M61A 1PICA 5IBSA 1LKKA 1O42A 2B3OA 1K9AA 4H1OA 1BG1A 3IN7A 1RJAA 2KK6A 3OB1B 4K45A 3OB2B 3US4A 3CXLA 3VS1A 3KFJA 1HCSB 1AYCA 3BUMB 1UUSA 2HUWA 2C9WA 2OQ1A 1O4MA 1MILA 2CBLA 1P13A 2KNOA 2L4KA 5GJIA 2VIFA 3MXYA 3MAZA 3PJPA 4OHIA 1SKJA 1D1ZA 2DLZA 1O43A 1BFIA 1OO4A 3TKZA 2IUIA 4M4ZA 2CIAA 3IMJA 5DC4A 4TZIA 1R1SA 3UF4A 2AOAA 2OZOA 1OPLA 1O4OA 1QADA 4WWQA 1NZLA 1O48A 2PTKA 1TZEE 1JYUA 4H34A 1NZVA 1O4PA 3OV1A 1A1BA 1A81A 2EOBA 1O45A 3VS5A 2HCKA 1I3ZA 2IUGA 4OHDA 1WQUA 1AD5A 1FBVA 1YVHA 4OHEA 1RQQC 1JU5A 4E93A 4EY0A 1A1CA 2GSBA 2DLYA 1O4IA 3N84A 4FL3A 4XZ0A 2IUHA 1AYDA 1CWDL 2HMHA 2MQIA 1YVLA 4D8KA 2Y3AB 1TCEA 1SHDA 3CBLA 3VS6A 2SRCA 1OO3A 4U1PA 1O4NA 1RPYA 1ZFPE 1A08A 4F59A 2EYYA 1D4TA 4K2RA 1KSWA 3BUNB 1O4AA 2MC1A 1FYRA 1M27A 4F5BA 2LCTA 5J3XA 3BKBA 2FO0A 1SHAA 1O4KA 1F1WA 3OP0A 3ZNIA 1UURA 2LNXA 2Y1NA 3BUOB 3PFVA 4LUEA 3VS7A 2L3TA 3EAZA 1LKLA 3VRNA 1SHBA 3VRRA 1X0NA 1B47A 2EL8A 2CS0A 5EEQA 2Y1MA 5EG3B 4NWFA 1QCFA 3IN8A 5DF6A 2EU0A 4P9VA 2HDVA 4A4CA 4K11A 5HKWA 1FBZA 1LUNA 4GPLB 1X27A 1O4HA 3PS5A 2EYZA 2LQNA 1SPSA 3PQZA 3VS0A 2PNAA 1D4WA 3PSJA 1Y1UA 1LCKA 4JE4A 3VROA 3S8NA 1GHUA 4K44A 2QMSA 3VRPA 4XZ1A 5EHRA 1BM2A 1MW4A 1QG1E 1A1AA 4DGPA 1BHHB 3QWYA 5I6VA 1BFJA 1BHFA 2C0TA 4ROJA 1F2FA 2AOBA 3NHNA 3IMDA 1A09A 2CI9A 1KA7A 1Z3KA 3M7FA 2CRHA 3QWXX 5GJHA 4FBNA 4LUDA 1NRVA 3S8OA 4GWFA 5EELA 3VS2A 1HCTB 3VS3A 2K79B 2HDXA 3GQIB 5IBMA 4X6SA 2RVFA 1FU6A 1BF5A 2DCRA 4QSYA 3VRZA 2H46E 3HHMB 1JWOA 2MRJA 2SHPA 2PNBA 1FU5A 3N8MA 1O4DA 1IJRA 5EHPA 1AOTF 2C0IA 1X6CA 1CSYA 1O44A 1JYRA 2ETZA 4U17A 4OHHA 1O4QA 5AXIA 5AULA 3MXCA 1A1EA 4JEGA 2RMXA 1XA6A 3T04A 1KA6A 1BLJA 4JGHA 2PLDA 2K7AB 1O47A 3WA4A 2LNWA 2DM0A 3BUXB 1O4CA 1BKMA 4GL9E 1CJ1A 1LUMA 1O46A 2L6KA 5D0JA 1O4FA 2RSYA 2MK2A 2FCIA 2JYQA 1O4LA 4P9ZA 4NWGA 1LUIA 1Y57A 3VRYA 2CI8A 4EIHA 1H9OA 3PLFB 1CWEA 4DGXA 2C0OA 1O4EA 1AYAA 3EACA 2AUGA 3CD3A 2LQWA 1BMBA 2EKXA 1BLKA 3C7IA 5BO4A 3OVEA 3PSKA 1JYQA 2EO3A 3GXWA 3BUWB 1R1QA 1AYBA 2CR4A 2RORA 3VRQA 3UYOA 1GRIA 2YSXA 1CSZA 1BKLA 3VS4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ECD A;  5KAZ A;  1G83 A;  1LUK A;  1SPR A;  2ABL A;  1OPK A;  1O4R A;  4E68 A;  3S9K A;  1AOU F;  5DC9 A;  5DC0 B;  3GXX A;  2EO6 A;  2IZV A;  2H5K A;  4L1B B;  5CDW A;  1O4G A;  3HCK A;  4OHL A;  1AB2 A;  2PLE A;  3N7Y A;  2DX0 A;  1KC2 A;  3VGO A;  3CWG A;  2YU7 A;  1O49 A;  2DVJ A;  1O4B A;  2XP1 A;  3TL0 A;  1LCJ A;  2H8H A;  1IS0 A;  3S8L A;  5HKZ A;  4A4B A;  1O4J A;  2GE9 A;  1O41 A;  2MRK A;  4FL2 A;  2BBU A;  5HKY A;  2EYV A;  1R1P A;  3HIZ B;  3K2M A;  1A07 A;  1FMK A;  1FHS A;  4F5A A;  1BHH A;  1M61 A;  1PIC A;  5IBS A;  1LKK A;  1O42 A;  2B3O A;  1K9A A;  4H1O A;  1BG1 A;  3IN7 A;  1RJA A;  2KK6 A;  3OB1 B;  4K45 A;  3OB2 B;  3US4 A;  3CXL A;  3VS1 A;  3KFJ A;  1HCS B;  1AYC A;  3BUM B;  1UUS A;  2HUW A;  2C9W A;  2OQ1 A;  1O4M A;  1MIL A;  2CBL A;  1P13 A;  2KNO A;  2L4K A;  5GJI A;  2VIF A;  3MXY A;  3MAZ A;  3PJP A;  4OHI A;  1SKJ A;  1D1Z A;  2DLZ A;  1O43 A;  1BFI A;  1OO4 A;  3TKZ A;  2IUI A;  4M4Z A;  2CIA A;  3IMJ A;  5DC4 A;  4TZI A;  1R1S A;  3UF4 A;  2AOA A;  2OZO A;  1OPL A;  1O4O A;  1QAD A;  4WWQ A;  1NZL A;  1O48 A;  2PTK A;  1TZE E;  1JYU A;  4H34 A;  1NZV A;  1O4P A;  3OV1 A;  1A1B A;  1A81 A;  2EOB A;  1O45 A;  3VS5 A;  2HCK A;  1I3Z A;  2IUG A;  4OHD A;  1WQU A;  1AD5 A;  1FBV A;  1YVH A;  4OHE A;  1RQQ C;  1JU5 A;  4E93 A;  4EY0 A;  1A1C A;  2GSB A;  2DLY A;  1O4I A;  3N84 A;  4FL3 A;  4XZ0 A;  2IUH A;  1AYD A;  1CWD L;  2HMH A;  2MQI A;  1YVL A;  4D8K A;  2Y3A B;  1TCE A;  1SHD A;  3CBL A;  3VS6 A;  2SRC A;  1OO3 A;  4U1P A;  1O4N A;  1RPY A;  1ZFP E;  1A08 A;  4F59 A;  2EYY A;  1D4T A;  4K2R A;  1KSW A;  3BUN B;  1O4A A;  2MC1 A;  1FYR A;  1M27 A;  4F5B A;  2LCT A;  5J3X A;  3BKB A;  2FO0 A;  1SHA A;  1O4K A;  1F1W A;  3OP0 A;  3ZNI A;  1UUR A;  2LNX A;  2Y1N A;  3BUO B;  3PFV A;  4LUE A;  3VS7 A;  2L3T A;  3EAZ A;  1LKL A;  3VRN A;  1SHB A;  3VRR A;  1X0N A;  1B47 A;  2EL8 A;  2CS0 A;  5EEQ A;  2Y1M A;  5EG3 B;  4NWF A;  1QCF A;  3IN8 A;  5DF6 A;  2EU0 A;  4P9V A;  2HDV A;  4A4C A;  4K11 A;  5HKW A;  1FBZ A;  1LUN A;  4GPL B;  1X27 A;  1O4H A;  3PS5 A;  2EYZ A;  2LQN A;  1SPS A;  3PQZ A;  3VS0 A;  2PNA A;  1D4W A;  3PSJ A;  1Y1U A;  1LCK A;  4JE4 A;  3VRO A;  3S8N A;  1GHU A;  4K44 A;  2QMS A;  3VRP A;  4XZ1 A;  5EHR A;  1BM2 A;  1MW4 A;  1QG1 E;  1A1A A;  4DGP A;  1BHH B;  3QWY A;  5I6V A;  1BFJ A;  1BHF A;  2C0T A;  4ROJ A;  1F2F A;  2AOB A;  3NHN A;  3IMD A;  1A09 A;  2CI9 A;  1KA7 A;  1Z3K A;  3M7F A;  2CRH A;  3QWX X;  5GJH A;  4FBN A;  4LUD A;  1NRV A;  3S8O A;  4GWF A;  5EEL A;  3VS2 A;  1HCT B;  3VS3 A;  2K79 B;  2HDX A;  3GQI B;  5IBM A;  4X6S A;  2RVF A;  1FU6 A;  1BF5 A;  2DCR A;  4QSY A;  3VRZ A;  2H46 E;  3HHM B;  1JWO A;  2MRJ A;  2SHP A;  2PNB A;  1FU5 A;  3N8M A;  1O4D A;  1IJR A;  5EHP A;  1AOT F;  2C0I A;  1X6C A;  1CSY A;  1O44 A;  1JYR A;  2ETZ A;  4U17 A;  4OHH A;  1O4Q A;  5AXI A;  5AUL A;  3MXC A;  1A1E A;  4JEG A;  2RMX A;  1XA6 A;  3T04 A;  1KA6 A;  1BLJ A;  4JGH A;  2PLD A;  2K7A B;  1O47 A;  3WA4 A;  2LNW A;  2DM0 A;  3BUX B;  1O4C A;  1BKM A;  4GL9 E;  1CJ1 A;  1LUM A;  1O46 A;  2L6K A;  5D0J A;  1O4F A;  2RSY A;  2MK2 A;  2FCI A;  2JYQ A;  1O4L A;  4P9Z A;  4NWG A;  1LUI A;  1Y57 A;  3VRY A;  2CI8 A;  4EIH A;  1H9O A;  3PLF B;  1CWE A;  4DGX A;  2C0O A;  1O4E A;  1AYA A;  3EAC A;  2AUG A;  3CD3 A;  2LQW A;  1BMB A;  2EKX A;  1BLK A;  3C7I A;  5BO4 A;  3OVE A;  3PSK A;  1JYQ A;  2EO3 A;  3GXW A;  3BUW B;  1R1Q A;  1AYB A;  2CR4 A;  2ROR A;  3VRQ A;  3UYO A;  1GRI A;  2YSX A;  1CSZ A;  1BKL A;  3VS4 A; 
#chains in the Genus database with same CATH topology
 2ECD A;  5KAZ A;  1G83 A;  1LUK A;  1SPR A;  2ABL A;  1OPK A;  1O4R A;  4E68 A;  3S9K A;  1AOU F;  5DC9 A;  5DC0 B;  3GXX A;  2EO6 A;  2IZV A;  2H5K A;  4L1B B;  5CDW A;  1O4G A;  3HCK A;  4OHL A;  1AB2 A;  2PLE A;  3N7Y A;  2DX0 A;  1KC2 A;  3VGO A;  3CWG A;  2YU7 A;  1O49 A;  2DVJ A;  1O4B A;  2XP1 A;  3TL0 A;  1LCJ A;  2H8H A;  1IS0 A;  3S8L A;  5HKZ A;  4A4B A;  1O4J A;  2GE9 A;  1O41 A;  2MRK A;  4FL2 A;  2BBU A;  5HKY A;  2EYV A;  1R1P A;  3HIZ B;  3K2M A;  1A07 A;  1FMK A;  1FHS A;  4F5A A;  1BHH A;  1M61 A;  1PIC A;  5IBS A;  1LKK A;  1O42 A;  2B3O A;  1K9A A;  4H1O A;  1BG1 A;  3IN7 A;  1RJA A;  2KK6 A;  3OB1 B;  4K45 A;  3OB2 B;  3US4 A;  3CXL A;  3VS1 A;  3KFJ A;  1HCS B;  1AYC A;  3BUM B;  1UUS A;  2HUW A;  2C9W A;  2OQ1 A;  1O4M A;  1MIL A;  2CBL A;  1P13 A;  2KNO A;  2L4K A;  5GJI A;  2VIF A;  3MXY A;  3MAZ A;  3PJP A;  4OHI A;  1SKJ A;  1D1Z A;  2DLZ A;  1O43 A;  1BFI A;  1OO4 A;  3TKZ A;  2IUI A;  4M4Z A;  2CIA A;  3IMJ A;  5DC4 A;  4TZI A;  1R1S A;  3UF4 A;  2AOA A;  2OZO A;  1OPL A;  1O4O A;  1QAD A;  4WWQ A;  1NZL A;  1O48 A;  2PTK A;  1TZE E;  1JYU A;  4H34 A;  1NZV A;  1O4P A;  3OV1 A;  1A1B A;  1A81 A;  2EOB A;  1O45 A;  3VS5 A;  2HCK A;  1I3Z A;  2IUG A;  4OHD A;  1WQU A;  1AD5 A;  3K2T A;  1FBV A;  1YVH A;  4OHE A;  1RQQ C;  1JU5 A;  4E93 A;  4EY0 A;  1A1C A;  2GSB A;  2DLY A;  1O4I A;  3N84 A;  2LRA A;  4FL3 A;  4XZ0 A;  2IUH A;  1AYD A;  1CWD L;  2HMH A;  2MQI A;  1YVL A;  4D8K A;  2Y3A B;  1TCE A;  1SHD A;  3CBL A;  3VS6 A;  2SRC A;  1OO3 A;  4U1P A;  1O4N A;  1RPY A;  1ZFP E;  1A08 A;  4F59 A;  2EYY A;  1D4T A;  4K2R A;  1KSW A;  3BUN B;  1O4A A;  2MC1 A;  1FYR A;  1M27 A;  4F5B A;  2LCT A;  5J3X A;  3BKB A;  2FO0 A;  1SHA A;  1O4K A;  1F1W A;  3OP0 A;  3ZNI A;  1UUR A;  2LNX A;  2Y1N A;  3BUO B;  3PFV A;  4LUE A;  3VS7 A;  2L3T A;  3EAZ A;  1LKL A;  3VRN A;  1SHB A;  3VRR A;  1X0N A;  1B47 A;  2EL8 A;  2CS0 A;  5EEQ A;  2Y1M A;  5EG3 B;  4NWF A;  1QCF A;  3IN8 A;  5DF6 A;  2EU0 A;  4P9V A;  2HDV A;  4A4C A;  4K11 A;  5HKW A;  1FBZ A;  1LUN A;  4GPL B;  1X27 A;  1O4H A;  3PS5 A;  2EYZ A;  2LQN A;  1SPS A;  3PQZ A;  3VS0 A;  2PNA A;  1D4W A;  3PSJ A;  1Y1U A;  1LCK A;  2KGY A;  4JE4 A;  3VRO A;  3S8N A;  1GHU A;  4K44 A;  2QMS A;  3VRP A;  4XZ1 A;  5EHR A;  1BM2 A;  1MW4 A;  1QG1 E;  1A1A A;  4DGP A;  1BHH B;  3QWY A;  5I6V A;  1BFJ A;  1BHF A;  2C0T A;  4ROJ A;  1F2F A;  2AOB A;  3NHN A;  3IMD A;  1A09 A;  2CI9 A;  1KA7 A;  1Z3K A;  3M7F A;  2CRH A;  3QWX X;  5GJH A;  4FBN A;  4LUD A;  1NRV A;  3S8O A;  4GWF A;  5EEL A;  3VS2 A;  1HCT B;  3VS3 A;  2K79 B;  2HDX A;  3GQI B;  5IBM A;  4X6S A;  2RVF A;  1FU6 A;  1BF5 A;  2DCR A;  4QSY A;  3VRZ A;  2H46 E;  3HHM B;  1JWO A;  2MRJ A;  2SHP A;  2PNB A;  1FU5 A;  3N8M A;  1O4D A;  1IJR A;  5EHP A;  1AOT F;  2C0I A;  1X6C A;  1CSY A;  1O44 A;  1JYR A;  2ETZ A;  4U17 A;  4OHH A;  1O4Q A;  5AXI A;  5AUL A;  3MXC A;  1A1E A;  4JEG A;  2RMX A;  1XA6 A;  3T04 A;  1KA6 A;  1BLJ A;  4JGH A;  2PLD A;  2K7A B;  1O47 A;  3WA4 A;  2LNW A;  2DM0 A;  3BUX B;  1O4C A;  1BKM A;  4GL9 E;  1CJ1 A;  1LUM A;  1O46 A;  2L6K A;  5D0J A;  1O4F A;  2RSY A;  2MK2 A;  2FCI A;  2JYQ A;  1O4L A;  4P9Z A;  4NWG A;  1LUI A;  1Y57 A;  3VRY A;  2CI8 A;  4EIH A;  1H9O A;  3PLF B;  1CWE A;  4DGX A;  2C0O A;  1O4E A;  1AYA A;  3EAC A;  2AUG A;  3CD3 A;  2LQW A;  1BMB A;  2EKX A;  1BLK A;  3C7I A;  5BO4 A;  3OVE A;  3LYV A;  3PSK A;  1JYQ A;  2EO3 A;  3GXW A;  3BUW B;  1R1Q A;  1AYB A;  2CR4 A;  2ROR A;  3VRQ A;  3UYO A;  1GRI A;  2YSX A;  1CSZ A;  1BKL A;  3VS4 A; 
#chains in the Genus database with same CATH homology
 2ECD A;  5KAZ A;  1G83 A;  1LUK A;  1SPR A;  2ABL A;  1OPK A;  1O4R A;  4E68 A;  3S9K A;  1AOU F;  5DC9 A;  5DC0 B;  3GXX A;  2EO6 A;  2IZV A;  2H5K A;  4L1B B;  5CDW A;  1O4G A;  3HCK A;  4OHL A;  1AB2 A;  2PLE A;  3N7Y A;  2DX0 A;  1KC2 A;  3VGO A;  3CWG A;  2YU7 A;  1O49 A;  2DVJ A;  1O4B A;  2XP1 A;  3TL0 A;  1LCJ A;  2H8H A;  1IS0 A;  3S8L A;  5HKZ A;  4A4B A;  1O4J A;  2GE9 A;  1O41 A;  2MRK A;  4FL2 A;  2BBU A;  5HKY A;  2EYV A;  1R1P A;  3HIZ B;  3K2M A;  1A07 A;  1FMK A;  1FHS A;  4F5A A;  1BHH A;  1M61 A;  1PIC A;  5IBS A;  1LKK A;  1O42 A;  2B3O A;  1K9A A;  4H1O A;  1BG1 A;  3IN7 A;  1RJA A;  2KK6 A;  3OB1 B;  4K45 A;  3OB2 B;  3US4 A;  3CXL A;  3VS1 A;  3KFJ A;  1HCS B;  1AYC A;  3BUM B;  1UUS A;  2HUW A;  2C9W A;  2OQ1 A;  1O4M A;  1MIL A;  2CBL A;  1P13 A;  2KNO A;  2L4K A;  5GJI A;  2VIF A;  3MXY A;  3MAZ A;  3PJP A;  4OHI A;  1SKJ A;  1D1Z A;  2DLZ A;  1O43 A;  1BFI A;  1OO4 A;  3TKZ A;  2IUI A;  4M4Z A;  2CIA A;  3IMJ A;  5DC4 A;  4TZI A;  1R1S A;  3UF4 A;  2AOA A;  2OZO A;  1OPL A;  1O4O A;  1QAD A;  4WWQ A;  1NZL A;  1O48 A;  2PTK A;  1TZE E;  1JYU A;  4H34 A;  1NZV A;  1O4P A;  3OV1 A;  1A1B A;  1A81 A;  2EOB A;  1O45 A;  3VS5 A;  2HCK A;  1I3Z A;  2IUG A;  4OHD A;  1WQU A;  1AD5 A;  1FBV A;  1YVH A;  4OHE A;  1RQQ C;  1JU5 A;  4E93 A;  4EY0 A;  1A1C A;  2GSB A;  2DLY A;  1O4I A;  3N84 A;  4FL3 A;  4XZ0 A;  2IUH A;  1AYD A;  1CWD L;  2HMH A;  2MQI A;  1YVL A;  4D8K A;  2Y3A B;  1TCE A;  1SHD A;  3CBL A;  3VS6 A;  2SRC A;  1OO3 A;  4U1P A;  1O4N A;  1RPY A;  1ZFP E;  1A08 A;  4F59 A;  2EYY A;  1D4T A;  4K2R A;  1KSW A;  3BUN B;  1O4A A;  2MC1 A;  1FYR A;  1M27 A;  4F5B A;  2LCT A;  5J3X A;  3BKB A;  2FO0 A;  1SHA A;  1O4K A;  1F1W A;  3OP0 A;  3ZNI A;  1UUR A;  2LNX A;  2Y1N A;  3BUO B;  3PFV A;  4LUE A;  3VS7 A;  2L3T A;  3EAZ A;  1LKL A;  3VRN A;  1SHB A;  3VRR A;  1X0N A;  1B47 A;  2EL8 A;  2CS0 A;  5EEQ A;  2Y1M A;  5EG3 B;  4NWF A;  1QCF A;  3IN8 A;  5DF6 A;  2EU0 A;  4P9V A;  2HDV A;  4A4C A;  4K11 A;  5HKW A;  1FBZ A;  1LUN A;  4GPL B;  1X27 A;  1O4H A;  3PS5 A;  2EYZ A;  2LQN A;  1SPS A;  3PQZ A;  3VS0 A;  2PNA A;  1D4W A;  3PSJ A;  1Y1U A;  1LCK A;  4JE4 A;  3VRO A;  3S8N A;  1GHU A;  4K44 A;  2QMS A;  3VRP A;  4XZ1 A;  5EHR A;  1BM2 A;  1MW4 A;  1QG1 E;  1A1A A;  4DGP A;  1BHH B;  3QWY A;  5I6V A;  1BFJ A;  1BHF A;  2C0T A;  4ROJ A;  1F2F A;  2AOB A;  3NHN A;  3IMD A;  1A09 A;  2CI9 A;  1KA7 A;  1Z3K A;  3M7F A;  2CRH A;  3QWX X;  5GJH A;  4FBN A;  4LUD A;  1NRV A;  3S8O A;  4GWF A;  5EEL A;  3VS2 A;  1HCT B;  3VS3 A;  2K79 B;  2HDX A;  3GQI B;  5IBM A;  4X6S A;  2RVF A;  1FU6 A;  1BF5 A;  2DCR A;  4QSY A;  3VRZ A;  2H46 E;  3HHM B;  1JWO A;  2MRJ A;  2SHP A;  2PNB A;  1FU5 A;  3N8M A;  1O4D A;  1IJR A;  5EHP A;  1AOT F;  2C0I A;  1X6C A;  1CSY A;  1O44 A;  1JYR A;  2ETZ A;  4U17 A;  4OHH A;  1O4Q A;  5AXI A;  5AUL A;  3MXC A;  1A1E A;  4JEG A;  2RMX A;  1XA6 A;  3T04 A;  1KA6 A;  1BLJ A;  4JGH A;  2PLD A;  2K7A B;  1O47 A;  3WA4 A;  2LNW A;  2DM0 A;  3BUX B;  1O4C A;  1BKM A;  4GL9 E;  1CJ1 A;  1LUM A;  1O46 A;  2L6K A;  5D0J A;  1O4F A;  2RSY A;  2MK2 A;  2FCI A;  2JYQ A;  1O4L A;  4P9Z A;  4NWG A;  1LUI A;  1Y57 A;  3VRY A;  2CI8 A;  4EIH A;  1H9O A;  3PLF B;  1CWE A;  4DGX A;  2C0O A;  1O4E A;  1AYA A;  3EAC A;  2AUG A;  3CD3 A;  2LQW A;  1BMB A;  2EKX A;  1BLK A;  3C7I A;  5BO4 A;  3OVE A;  3PSK A;  1JYQ A;  2EO3 A;  3GXW A;  3BUW B;  1R1Q A;  1AYB A;  2CR4 A;  2ROR A;  3VRQ A;  3UYO A;  1GRI A;  2YSX A;  1CSZ A;  1BKL A;  3VS4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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