3OV1A

Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
101
structure length
101
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
pubmed doi rcsb
molecule tags Signaling protein/antagonist
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 25
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2010-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3ov1A00
3CXLA 3IN7A 1AYCA 4F59A 2EKXA 4NWFA 1P13A 1BKLA 3T04A 3VS5A 1I3ZA 1JU5A 4P9VA 4ROJA 2C9WA 1QG1E 3N8MA 2RSYA 5J3XA 4LUDA 3BUOB 1BFIA 1BLKA 3IMDA 1SPSA 2L3TA 1QADA 3UYOA 2MQIA 2DX0A 1BHHB 1G83A 2KK6A 4X6SA 5D0JA 5AXIA 1X27A 1O4IA 1RQQC 2CS0A 3EAZA 3VS3A 1FBZA 5BO4A 1XA6A 1YVHA 3OVEA 3QWXX 4K44A 4A4CA 1FBVA 4F5AA 3VS0A 2MRJA 4K11A 3N7YA 5EG3B 2Y1NA 2ABLA 2FO0A 2EO3A 2IZVA 1O49A 3N84A 4DGXA 5HKWA 2DLZA 2JYQA 1TZEE 1AYDA 1K9AA 1CWEA 1CWDL 4E68A 1JYQA 1OO4A 1IJRA 1O43A 3PLFB 4OHLA 1O4CA 1BFJA 2CBLA 1NZLA 4XZ1A 5HKYA 3IMJA 3EACA 4JEGA 1A08A 3VS6A 1BG1A 3GXWA 2L4KA 2HUWA 1AYBA 1O4NA 3IN8A 5DC0B 1O4EA 2LNWA 1RJAA 2KNOA 2SHPA 3PJPA 4OHIA 1LUIA 1AOUF 2C0IA 2IUHA 1F1WA 1YVLA 1O4BA 3MAZA 1O4FA 2DLYA 1M61A 3VRQA 1PICA 2IUGA 2VIFA 1D4WA 1MILA 3BKBA 4QSYA 4NWGA 1O41A 3S8LA 4EIHA 2FCIA 3WA4A 1O44A 3S8OA 5AULA 1QCFA 1GRIA 1A81A 1D1ZA 1BHFA 1O46A 2DVJA 2H46E 2OQ1A 3TKZA 2LCTA 1O4HA 1F2FA 2K79B 4A4BA 1KA7A 4EY0A 3UF4A 3HIZB 1Y57A 1H9OA 3MXYA 3S8NA 1AOTF 1O4DA 1LKLA 3VS4A 3BUMB 3GQIB 4H34A 5EHRA 4E93A 1O4QA 3C7IA 4FBNA 3VRZA 3VROA 1A09A 1WQUA 4U17A 5GJIA 2AOAA 1SPRA 2EL8A 2HDXA 1UUSA 2PLDA 1O42A 4GPLB 1SHDA 1JYUA 2RMXA 3BUWB 4LUEA 1O4JA 2PNBA 1SHBA 1O4MA 1LCKA 2QMSA 3S9KA 1O4LA 2GE9A 1FYRA 1UURA 1O4OA 1SHAA 5DC4A 2OZOA 2XP1A 2MC1A 3CBLA 2Y3AB 1A07A 2LNXA 3OB1B 2LQWA 3PSKA 1CSZA 1OPLA 5HKZA 4GWFA 2MRKA 1JYRA 3NHNA 2IUIA 1A1EA 1FU5A 3VRPA 1LUKA 4OHHA 2CRHA 3M7FA 1FMKA 1FHSA 2CI8A 2LQNA 2YU7A 1O4RA 2PTKA 1B47A 2B3OA 3HHMB 4JGHA 2PLEA 1BF5A 2EOBA 1A1BA 2C0OA 5EEQA 2EYYA 3ZNIA 1KSWA 2RVFA 3MXCA 1A1AA 4M4ZA 3CD3A 1FU6A 3PFVA 3VRNA 4OHDA 1BLJA 1R1QA 4WWQA 3VS7A 4F5BA 1CSYA 3PSJA 3HCKA 3VRRA 1O48A 3VGOA 4FL2A 1SKJA 3VS2A 5CDWA 5IBSA 1LUMA 4FL3A 1BKMA 1O47A 2BBUA 2H8HA 5EELA 1X0NA 1HCSB 4OHEA 1X6CA 2Y1MA 5DC9A 1GHUA 1M27A 1NZVA 2HDVA 1Y1UA 2CR4A 1R1PA 2MK2A 2HCKA 2EYZA 3PQZA 3PS5A 1LKKA 4H1OA 2CIAA 3US4A 2AOBA 5GJHA 4GL9E 1JWOA 5DF6A 1O4GA 2ETZA 1LCJA 2YSXA 3KFJA 1A1CA 3VRYA 4U1PA 5I6VA 3BUXB 3TL0A 1D4TA 1BMBA 4K45A 3K2MA 1AD5A 4D8KA 1OPKA 1MW4A 2CI9A 1AB2A 3OP0A 3VS1A 4K2RA 3OV1A 2L6KA 1R1SA 5IBMA 2EYVA 1O4KA 1KA6A 1O4PA 2HMHA 1O45A 2ECDA 2PNAA 2C0TA 2SRCA 1HCTB 1IS0A 5KAZA 1AYAA 4TZIA 5EHPA 1TCEA 2DM0A 4XZ0A 3QWYA 1LUNA 1O4AA 2H5KA 1KC2A 1BHHA 3OB2B 2GSBA 3BUNB 1Z3KA 1RPYA 2DCRA 2EU0A 3GXXA 4JE4A 2K7AB 2RORA 1ZFPE 3CWGA 4P9ZA 1NRVA 2EO6A 1BM2A 2AUGA 1CJ1A 1OO3A 4L1BB 4DGPA
chains in the Genus database with same CATH superfamily
3CXLA 3IN7A 1AYCA 4F59A 2EKXA 4NWFA 1P13A 1BKLA 3T04A 3VS5A 1I3ZA 1JU5A 4P9VA 4ROJA 2C9WA 1QG1E 3N8MA 2RSYA 5J3XA 4LUDA 3BUOB 1BFIA 1BLKA 3IMDA 1SPSA 2L3TA 1QADA 3UYOA 2MQIA 2DX0A 1BHHB 1G83A 2KK6A 4X6SA 5D0JA 5AXIA 1X27A 1O4IA 1RQQC 2CS0A 3EAZA 3VS3A 1FBZA 5BO4A 1XA6A 1YVHA 3OVEA 3QWXX 4K44A 4A4CA 1FBVA 4F5AA 3VS0A 2MRJA 4K11A 3N7YA 5EG3B 2Y1NA 2ABLA 2FO0A 2EO3A 2IZVA 1O49A 3N84A 4DGXA 5HKWA 2DLZA 2JYQA 1TZEE 1AYDA 1K9AA 1CWEA 1CWDL 4E68A 1JYQA 1OO4A 1IJRA 1O43A 3PLFB 4OHLA 1O4CA 1BFJA 2CBLA 1NZLA 4XZ1A 5HKYA 3IMJA 3EACA 4JEGA 1A08A 3VS6A 1BG1A 3GXWA 2L4KA 2HUWA 1AYBA 1O4NA 3IN8A 5DC0B 1O4EA 2LNWA 1RJAA 2KNOA 2SHPA 3PJPA 4OHIA 1LUIA 1AOUF 2C0IA 2IUHA 1F1WA 1YVLA 3LYVA 1O4BA 3MAZA 1O4FA 2DLYA 1M61A 3VRQA 1PICA 2IUGA 2VIFA 1D4WA 1MILA 3BKBA 4QSYA 4NWGA 1O41A 3S8LA 4EIHA 2FCIA 3WA4A 1O44A 3S8OA 5AULA 1QCFA 1GRIA 1A81A 1D1ZA 1BHFA 1O46A 2DVJA 2H46E 2OQ1A 3TKZA 2LCTA 1O4HA 1F2FA 2K79B 4A4BA 1KA7A 4EY0A 3UF4A 3HIZB 1Y57A 1H9OA 3MXYA 3S8NA 1AOTF 1O4DA 1LKLA 3VS4A 3BUMB 3GQIB 4H34A 5EHRA 4E93A 1O4QA 3C7IA 4FBNA 3VRZA 3VROA 1A09A 1WQUA 4U17A 5GJIA 2AOAA 1SPRA 2EL8A 2HDXA 1UUSA 2PLDA 1O42A 4GPLB 1SHDA 1JYUA 2RMXA 3BUWB 4LUEA 1O4JA 2PNBA 1SHBA 1O4MA 1LCKA 2QMSA 3S9KA 1O4LA 2GE9A 1FYRA 1UURA 1O4OA 1SHAA 5DC4A 2OZOA 2XP1A 2MC1A 3CBLA 2Y3AB 1A07A 2LNXA 3OB1B 2LQWA 3PSKA 1CSZA 1OPLA 5HKZA 4GWFA 2MRKA 1JYRA 3NHNA 2IUIA 1A1EA 1FU5A 3VRPA 1LUKA 4OHHA 2CRHA 2LRAA 3M7FA 1FMKA 1FHSA 2CI8A 2LQNA 2YU7A 1O4RA 2PTKA 1B47A 2B3OA 3HHMB 4JGHA 2PLEA 1BF5A 2EOBA 1A1BA 2C0OA 5EEQA 2EYYA 3ZNIA 1KSWA 2RVFA 3MXCA 1A1AA 4M4ZA 3CD3A 1FU6A 3PFVA 3VRNA 4OHDA 1BLJA 1R1QA 4WWQA 3VS7A 4F5BA 1CSYA 3PSJA 3HCKA 3VRRA 1O48A 3VGOA 4FL2A 1SKJA 3VS2A 5CDWA 5IBSA 1LUMA 4FL3A 1BKMA 1O47A 2BBUA 2H8HA 5EELA 1X0NA 1HCSB 4OHEA 1X6CA 2Y1MA 5DC9A 1GHUA 1M27A 1NZVA 2HDVA 1Y1UA 2CR4A 1R1PA 2MK2A 2HCKA 2EYZA 3PQZA 3PS5A 1LKKA 4H1OA 2CIAA 3K2TA 3US4A 2AOBA 5GJHA 4GL9E 1JWOA 5DF6A 1O4GA 2ETZA 1LCJA 2YSXA 3KFJA 1A1CA 3VRYA 4U1PA 5I6VA 3BUXB 3TL0A 1D4TA 1BMBA 4K45A 3K2MA 1AD5A 4D8KA 1OPKA 1MW4A 2CI9A 1AB2A 3OP0A 3VS1A 4K2RA 3OV1A 2L6KA 1R1SA 5IBMA 2EYVA 1O4KA 1KA6A 1O4PA 2HMHA 1O45A 2ECDA 2PNAA 2C0TA 2SRCA 1HCTB 1IS0A 5KAZA 1AYAA 4TZIA 5EHPA 1TCEA 2DM0A 4XZ0A 3QWYA 1LUNA 1O4AA 2H5KA 1KC2A 1BHHA 3OB2B 2GSBA 3BUNB 1Z3KA 1RPYA 2DCRA 2EU0A 3GXXA 4JE4A 2K7AB 2RORA 1ZFPE 2KGYA 3CWGA 4P9ZA 1NRVA 2EO6A 1BM2A 2AUGA 1CJ1A 1OO3A 4L1BB 4DGPA
chains in the Genus database with same CATH topology
3CXLA 3IN7A 1AYCA 4F59A 2EKXA 4NWFA 1P13A 1BKLA 3T04A 3VS5A 1I3ZA 1JU5A 4P9VA 4ROJA 2C9WA 1QG1E 3N8MA 2RSYA 5J3XA 4LUDA 3BUOB 1BFIA 1BLKA 3IMDA 1SPSA 2L3TA 1QADA 3UYOA 2MQIA 2DX0A 1BHHB 1G83A 2KK6A 4X6SA 5D0JA 5AXIA 1X27A 1O4IA 1RQQC 2CS0A 3EAZA 3VS3A 1FBZA 5BO4A 1XA6A 1YVHA 3OVEA 3QWXX 4K44A 4A4CA 1FBVA 4F5AA 3VS0A 2MRJA 4K11A 3N7YA 5EG3B 2Y1NA 2ABLA 2FO0A 2EO3A 2IZVA 1O49A 3N84A 4DGXA 5HKWA 2DLZA 2JYQA 1TZEE 1AYDA 1K9AA 1CWEA 1CWDL 4E68A 1JYQA 1OO4A 1IJRA 1O43A 3PLFB 4OHLA 1O4CA 1BFJA 2CBLA 1NZLA 4XZ1A 5HKYA 3IMJA 3EACA 4JEGA 1A08A 3VS6A 1BG1A 3GXWA 2L4KA 2HUWA 1AYBA 1O4NA 3IN8A 5DC0B 1O4EA 2LNWA 1RJAA 2KNOA 2SHPA 3PJPA 4OHIA 1LUIA 1AOUF 2C0IA 2IUHA 1F1WA 1YVLA 1O4BA 3MAZA 1O4FA 2DLYA 1M61A 3VRQA 1PICA 2IUGA 2VIFA 1D4WA 1MILA 3BKBA 4QSYA 4NWGA 1O41A 3S8LA 4EIHA 2FCIA 3WA4A 1O44A 3S8OA 5AULA 1QCFA 1GRIA 1A81A 1D1ZA 1BHFA 1O46A 2DVJA 2H46E 2OQ1A 3TKZA 2LCTA 1O4HA 1F2FA 2K79B 4A4BA 1KA7A 4EY0A 3UF4A 3HIZB 1Y57A 1H9OA 3MXYA 3S8NA 1AOTF 1O4DA 1LKLA 3VS4A 3BUMB 3GQIB 4H34A 5EHRA 4E93A 1O4QA 3C7IA 4FBNA 3VRZA 3VROA 1A09A 1WQUA 4U17A 5GJIA 2AOAA 1SPRA 2EL8A 2HDXA 1UUSA 2PLDA 1O42A 4GPLB 1SHDA 1JYUA 2RMXA 3BUWB 4LUEA 1O4JA 2PNBA 1SHBA 1O4MA 1LCKA 2QMSA 3S9KA 1O4LA 2GE9A 1FYRA 1UURA 1O4OA 1SHAA 5DC4A 2OZOA 2XP1A 2MC1A 3CBLA 2Y3AB 1A07A 2LNXA 3OB1B 2LQWA 3PSKA 1CSZA 1OPLA 5HKZA 4GWFA 2MRKA 1JYRA 3NHNA 2IUIA 1A1EA 1FU5A 3VRPA 1LUKA 4OHHA 2CRHA 3M7FA 1FMKA 1FHSA 2CI8A 2LQNA 2YU7A 1O4RA 2PTKA 1B47A 2B3OA 3HHMB 4JGHA 2PLEA 1BF5A 2EOBA 1A1BA 2C0OA 5EEQA 2EYYA 3ZNIA 1KSWA 2RVFA 3MXCA 1A1AA 4M4ZA 3CD3A 1FU6A 3PFVA 3VRNA 4OHDA 1BLJA 1R1QA 4WWQA 3VS7A 4F5BA 1CSYA 3PSJA 3HCKA 3VRRA 1O48A 3VGOA 4FL2A 1SKJA 3VS2A 5CDWA 5IBSA 1LUMA 4FL3A 1BKMA 1O47A 2BBUA 2H8HA 5EELA 1X0NA 1HCSB 4OHEA 1X6CA 2Y1MA 5DC9A 1GHUA 1M27A 1NZVA 2HDVA 1Y1UA 2CR4A 1R1PA 2MK2A 2HCKA 2EYZA 3PQZA 3PS5A 1LKKA 4H1OA 2CIAA 3US4A 2AOBA 5GJHA 4GL9E 1JWOA 5DF6A 1O4GA 2ETZA 1LCJA 2YSXA 3KFJA 1A1CA 3VRYA 4U1PA 5I6VA 3BUXB 3TL0A 1D4TA 1BMBA 4K45A 3K2MA 1AD5A 4D8KA 1OPKA 1MW4A 2CI9A 1AB2A 3OP0A 3VS1A 4K2RA 3OV1A 2L6KA 1R1SA 5IBMA 2EYVA 1O4KA 1KA6A 1O4PA 2HMHA 1O45A 2ECDA 2PNAA 2C0TA 2SRCA 1HCTB 1IS0A 5KAZA 1AYAA 4TZIA 5EHPA 1TCEA 2DM0A 4XZ0A 3QWYA 1LUNA 1O4AA 2H5KA 1KC2A 1BHHA 3OB2B 2GSBA 3BUNB 1Z3KA 1RPYA 2DCRA 2EU0A 3GXXA 4JE4A 2K7AB 2RORA 1ZFPE 3CWGA 4P9ZA 1NRVA 2EO6A 1BM2A 2AUGA 1CJ1A 1OO3A 4L1BB 4DGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXL A;  3IN7 A;  1AYC A;  4F59 A;  2EKX A;  4NWF A;  1P13 A;  1BKL A;  3T04 A;  3VS5 A;  1I3Z A;  1JU5 A;  4P9V A;  4ROJ A;  2C9W A;  1QG1 E;  3N8M A;  2RSY A;  5J3X A;  4LUD A;  3BUO B;  1BFI A;  1BLK A;  3IMD A;  1SPS A;  2L3T A;  1QAD A;  3UYO A;  2MQI A;  2DX0 A;  1BHH B;  1G83 A;  2KK6 A;  4X6S A;  5D0J A;  5AXI A;  1X27 A;  1O4I A;  1RQQ C;  2CS0 A;  3EAZ A;  3VS3 A;  1FBZ A;  5BO4 A;  1XA6 A;  1YVH A;  3OVE A;  3QWX X;  4K44 A;  4A4C A;  1FBV A;  4F5A A;  3VS0 A;  2MRJ A;  4K11 A;  3N7Y A;  5EG3 B;  2Y1N A;  2ABL A;  2FO0 A;  2EO3 A;  2IZV A;  1O49 A;  3N84 A;  4DGX A;  5HKW A;  2DLZ A;  2JYQ A;  1TZE E;  1AYD A;  1K9A A;  1CWE A;  1CWD L;  4E68 A;  1JYQ A;  1OO4 A;  1IJR A;  1O43 A;  3PLF B;  4OHL A;  1O4C A;  1BFJ A;  2CBL A;  1NZL A;  4XZ1 A;  5HKY A;  3IMJ A;  3EAC A;  4JEG A;  1A08 A;  3VS6 A;  1BG1 A;  3GXW A;  2L4K A;  2HUW A;  1AYB A;  1O4N A;  3IN8 A;  5DC0 B;  1O4E A;  2LNW A;  1RJA A;  2KNO A;  2SHP A;  3PJP A;  4OHI A;  1LUI A;  1AOU F;  2C0I A;  2IUH A;  1F1W A;  1YVL A;  1O4B A;  3MAZ A;  1O4F A;  2DLY A;  1M61 A;  3VRQ A;  1PIC A;  2IUG A;  2VIF A;  1D4W A;  1MIL A;  3BKB A;  4QSY A;  4NWG A;  1O41 A;  3S8L A;  4EIH A;  2FCI A;  3WA4 A;  1O44 A;  3S8O A;  5AUL A;  1QCF A;  1GRI A;  1A81 A;  1D1Z A;  1BHF A;  1O46 A;  2DVJ A;  2H46 E;  2OQ1 A;  3TKZ A;  2LCT A;  1O4H A;  1F2F A;  2K79 B;  4A4B A;  1KA7 A;  4EY0 A;  3UF4 A;  3HIZ B;  1Y57 A;  1H9O A;  3MXY A;  3S8N A;  1AOT F;  1O4D A;  1LKL A;  3VS4 A;  3BUM B;  3GQI B;  4H34 A;  5EHR A;  4E93 A;  1O4Q A;  3C7I A;  4FBN A;  3VRZ A;  3VRO A;  1A09 A;  1WQU A;  4U17 A;  5GJI A;  2AOA A;  1SPR A;  2EL8 A;  2HDX A;  1UUS A;  2PLD A;  1O42 A;  4GPL B;  1SHD A;  1JYU A;  2RMX A;  3BUW B;  4LUE A;  1O4J A;  2PNB A;  1SHB A;  1O4M A;  1LCK A;  2QMS A;  3S9K A;  1O4L A;  2GE9 A;  1FYR A;  1UUR A;  1O4O A;  1SHA A;  5DC4 A;  2OZO A;  2XP1 A;  2MC1 A;  3CBL A;  2Y3A B;  1A07 A;  2LNX A;  3OB1 B;  2LQW A;  3PSK A;  1CSZ A;  1OPL A;  5HKZ A;  4GWF A;  2MRK A;  1JYR A;  3NHN A;  2IUI A;  1A1E A;  1FU5 A;  3VRP A;  1LUK A;  4OHH A;  2CRH A;  3M7F A;  1FMK A;  1FHS A;  2CI8 A;  2LQN A;  2YU7 A;  1O4R A;  2PTK A;  1B47 A;  2B3O A;  3HHM B;  4JGH A;  2PLE A;  1BF5 A;  2EOB A;  1A1B A;  2C0O A;  5EEQ A;  2EYY A;  3ZNI A;  1KSW A;  2RVF A;  3MXC A;  1A1A A;  4M4Z A;  3CD3 A;  1FU6 A;  3PFV A;  3VRN A;  4OHD A;  1BLJ A;  1R1Q A;  4WWQ A;  3VS7 A;  4F5B A;  1CSY A;  3PSJ A;  3HCK A;  3VRR A;  1O48 A;  3VGO A;  4FL2 A;  1SKJ A;  3VS2 A;  5CDW A;  5IBS A;  1LUM A;  4FL3 A;  1BKM A;  1O47 A;  2BBU A;  2H8H A;  5EEL A;  1X0N A;  1HCS B;  4OHE A;  1X6C A;  2Y1M A;  5DC9 A;  1GHU A;  1M27 A;  1NZV A;  2HDV A;  1Y1U A;  2CR4 A;  1R1P A;  2MK2 A;  2HCK A;  2EYZ A;  3PQZ A;  3PS5 A;  1LKK A;  4H1O A;  2CIA A;  3US4 A;  2AOB A;  5GJH A;  4GL9 E;  1JWO A;  5DF6 A;  1O4G A;  2ETZ A;  1LCJ A;  2YSX A;  3KFJ A;  1A1C A;  3VRY A;  4U1P A;  5I6V A;  3BUX B;  3TL0 A;  1D4T A;  1BMB A;  4K45 A;  3K2M A;  1AD5 A;  4D8K A;  1OPK A;  1MW4 A;  2CI9 A;  1AB2 A;  3OP0 A;  3VS1 A;  4K2R A;  3OV1 A;  2L6K A;  1R1S A;  5IBM A;  2EYV A;  1O4K A;  1KA6 A;  1O4P A;  2HMH A;  1O45 A;  2ECD A;  2PNA A;  2C0T A;  2SRC A;  1HCT B;  1IS0 A;  5KAZ A;  1AYA A;  4TZI A;  5EHP A;  1TCE A;  2DM0 A;  4XZ0 A;  3QWY A;  1LUN A;  1O4A A;  2H5K A;  1KC2 A;  1BHH A;  3OB2 B;  2GSB A;  3BUN B;  1Z3K A;  1RPY A;  2DCR A;  2EU0 A;  3GXX A;  4JE4 A;  2K7A B;  2ROR A;  1ZFP E;  3CWG A;  4P9Z A;  1NRV A;  2EO6 A;  1BM2 A;  2AUG A;  1CJ1 A;  1OO3 A;  4L1B B;  4DGP A; 
#chains in the Genus database with same CATH topology
 3CXL A;  3IN7 A;  1AYC A;  4F59 A;  2EKX A;  4NWF A;  1P13 A;  1BKL A;  3T04 A;  3VS5 A;  1I3Z A;  1JU5 A;  4P9V A;  4ROJ A;  2C9W A;  1QG1 E;  3N8M A;  2RSY A;  5J3X A;  4LUD A;  3BUO B;  1BFI A;  1BLK A;  3IMD A;  1SPS A;  2L3T A;  1QAD A;  3UYO A;  2MQI A;  2DX0 A;  1BHH B;  1G83 A;  2KK6 A;  4X6S A;  5D0J A;  5AXI A;  1X27 A;  1O4I A;  1RQQ C;  2CS0 A;  3EAZ A;  3VS3 A;  1FBZ A;  5BO4 A;  1XA6 A;  1YVH A;  3OVE A;  3QWX X;  4K44 A;  4A4C A;  1FBV A;  4F5A A;  3VS0 A;  2MRJ A;  4K11 A;  3N7Y A;  5EG3 B;  2Y1N A;  2ABL A;  2FO0 A;  2EO3 A;  2IZV A;  1O49 A;  3N84 A;  4DGX A;  5HKW A;  2DLZ A;  2JYQ A;  1TZE E;  1AYD A;  1K9A A;  1CWE A;  1CWD L;  4E68 A;  1JYQ A;  1OO4 A;  1IJR A;  1O43 A;  3PLF B;  4OHL A;  1O4C A;  1BFJ A;  2CBL A;  1NZL A;  4XZ1 A;  5HKY A;  3IMJ A;  3EAC A;  4JEG A;  1A08 A;  3VS6 A;  1BG1 A;  3GXW A;  2L4K A;  2HUW A;  1AYB A;  1O4N A;  3IN8 A;  5DC0 B;  1O4E A;  2LNW A;  1RJA A;  2KNO A;  2SHP A;  3PJP A;  4OHI A;  1LUI A;  1AOU F;  2C0I A;  2IUH A;  1F1W A;  1YVL A;  3LYV A;  1O4B A;  3MAZ A;  1O4F A;  2DLY A;  1M61 A;  3VRQ A;  1PIC A;  2IUG A;  2VIF A;  1D4W A;  1MIL A;  3BKB A;  4QSY A;  4NWG A;  1O41 A;  3S8L A;  4EIH A;  2FCI A;  3WA4 A;  1O44 A;  3S8O A;  5AUL A;  1QCF A;  1GRI A;  1A81 A;  1D1Z A;  1BHF A;  1O46 A;  2DVJ A;  2H46 E;  2OQ1 A;  3TKZ A;  2LCT A;  1O4H A;  1F2F A;  2K79 B;  4A4B A;  1KA7 A;  4EY0 A;  3UF4 A;  3HIZ B;  1Y57 A;  1H9O A;  3MXY A;  3S8N A;  1AOT F;  1O4D A;  1LKL A;  3VS4 A;  3BUM B;  3GQI B;  4H34 A;  5EHR A;  4E93 A;  1O4Q A;  3C7I A;  4FBN A;  3VRZ A;  3VRO A;  1A09 A;  1WQU A;  4U17 A;  5GJI A;  2AOA A;  1SPR A;  2EL8 A;  2HDX A;  1UUS A;  2PLD A;  1O42 A;  4GPL B;  1SHD A;  1JYU A;  2RMX A;  3BUW B;  4LUE A;  1O4J A;  2PNB A;  1SHB A;  1O4M A;  1LCK A;  2QMS A;  3S9K A;  1O4L A;  2GE9 A;  1FYR A;  1UUR A;  1O4O A;  1SHA A;  5DC4 A;  2OZO A;  2XP1 A;  2MC1 A;  3CBL A;  2Y3A B;  1A07 A;  2LNX A;  3OB1 B;  2LQW A;  3PSK A;  1CSZ A;  1OPL A;  5HKZ A;  4GWF A;  2MRK A;  1JYR A;  3NHN A;  2IUI A;  1A1E A;  1FU5 A;  3VRP A;  1LUK A;  4OHH A;  2CRH A;  2LRA A;  3M7F A;  1FMK A;  1FHS A;  2CI8 A;  2LQN A;  2YU7 A;  1O4R A;  2PTK A;  1B47 A;  2B3O A;  3HHM B;  4JGH A;  2PLE A;  1BF5 A;  2EOB A;  1A1B A;  2C0O A;  5EEQ A;  2EYY A;  3ZNI A;  1KSW A;  2RVF A;  3MXC A;  1A1A A;  4M4Z A;  3CD3 A;  1FU6 A;  3PFV A;  3VRN A;  4OHD A;  1BLJ A;  1R1Q A;  4WWQ A;  3VS7 A;  4F5B A;  1CSY A;  3PSJ A;  3HCK A;  3VRR A;  1O48 A;  3VGO A;  4FL2 A;  1SKJ A;  3VS2 A;  5CDW A;  5IBS A;  1LUM A;  4FL3 A;  1BKM A;  1O47 A;  2BBU A;  2H8H A;  5EEL A;  1X0N A;  1HCS B;  4OHE A;  1X6C A;  2Y1M A;  5DC9 A;  1GHU A;  1M27 A;  1NZV A;  2HDV A;  1Y1U A;  2CR4 A;  1R1P A;  2MK2 A;  2HCK A;  2EYZ A;  3PQZ A;  3PS5 A;  1LKK A;  4H1O A;  2CIA A;  3K2T A;  3US4 A;  2AOB A;  5GJH A;  4GL9 E;  1JWO A;  5DF6 A;  1O4G A;  2ETZ A;  1LCJ A;  2YSX A;  3KFJ A;  1A1C A;  3VRY A;  4U1P A;  5I6V A;  3BUX B;  3TL0 A;  1D4T A;  1BMB A;  4K45 A;  3K2M A;  1AD5 A;  4D8K A;  1OPK A;  1MW4 A;  2CI9 A;  1AB2 A;  3OP0 A;  3VS1 A;  4K2R A;  3OV1 A;  2L6K A;  1R1S A;  5IBM A;  2EYV A;  1O4K A;  1KA6 A;  1O4P A;  2HMH A;  1O45 A;  2ECD A;  2PNA A;  2C0T A;  2SRC A;  1HCT B;  1IS0 A;  5KAZ A;  1AYA A;  4TZI A;  5EHP A;  1TCE A;  2DM0 A;  4XZ0 A;  3QWY A;  1LUN A;  1O4A A;  2H5K A;  1KC2 A;  1BHH A;  3OB2 B;  2GSB A;  3BUN B;  1Z3K A;  1RPY A;  2DCR A;  2EU0 A;  3GXX A;  4JE4 A;  2K7A B;  2ROR A;  1ZFP E;  2KGY A;  3CWG A;  4P9Z A;  1NRV A;  2EO6 A;  1BM2 A;  2AUG A;  1CJ1 A;  1OO3 A;  4L1B B;  4DGP A; 
#chains in the Genus database with same CATH homology
 3CXL A;  3IN7 A;  1AYC A;  4F59 A;  2EKX A;  4NWF A;  1P13 A;  1BKL A;  3T04 A;  3VS5 A;  1I3Z A;  1JU5 A;  4P9V A;  4ROJ A;  2C9W A;  1QG1 E;  3N8M A;  2RSY A;  5J3X A;  4LUD A;  3BUO B;  1BFI A;  1BLK A;  3IMD A;  1SPS A;  2L3T A;  1QAD A;  3UYO A;  2MQI A;  2DX0 A;  1BHH B;  1G83 A;  2KK6 A;  4X6S A;  5D0J A;  5AXI A;  1X27 A;  1O4I A;  1RQQ C;  2CS0 A;  3EAZ A;  3VS3 A;  1FBZ A;  5BO4 A;  1XA6 A;  1YVH A;  3OVE A;  3QWX X;  4K44 A;  4A4C A;  1FBV A;  4F5A A;  3VS0 A;  2MRJ A;  4K11 A;  3N7Y A;  5EG3 B;  2Y1N A;  2ABL A;  2FO0 A;  2EO3 A;  2IZV A;  1O49 A;  3N84 A;  4DGX A;  5HKW A;  2DLZ A;  2JYQ A;  1TZE E;  1AYD A;  1K9A A;  1CWE A;  1CWD L;  4E68 A;  1JYQ A;  1OO4 A;  1IJR A;  1O43 A;  3PLF B;  4OHL A;  1O4C A;  1BFJ A;  2CBL A;  1NZL A;  4XZ1 A;  5HKY A;  3IMJ A;  3EAC A;  4JEG A;  1A08 A;  3VS6 A;  1BG1 A;  3GXW A;  2L4K A;  2HUW A;  1AYB A;  1O4N A;  3IN8 A;  5DC0 B;  1O4E A;  2LNW A;  1RJA A;  2KNO A;  2SHP A;  3PJP A;  4OHI A;  1LUI A;  1AOU F;  2C0I A;  2IUH A;  1F1W A;  1YVL A;  1O4B A;  3MAZ A;  1O4F A;  2DLY A;  1M61 A;  3VRQ A;  1PIC A;  2IUG A;  2VIF A;  1D4W A;  1MIL A;  3BKB A;  4QSY A;  4NWG A;  1O41 A;  3S8L A;  4EIH A;  2FCI A;  3WA4 A;  1O44 A;  3S8O A;  5AUL A;  1QCF A;  1GRI A;  1A81 A;  1D1Z A;  1BHF A;  1O46 A;  2DVJ A;  2H46 E;  2OQ1 A;  3TKZ A;  2LCT A;  1O4H A;  1F2F A;  2K79 B;  4A4B A;  1KA7 A;  4EY0 A;  3UF4 A;  3HIZ B;  1Y57 A;  1H9O A;  3MXY A;  3S8N A;  1AOT F;  1O4D A;  1LKL A;  3VS4 A;  3BUM B;  3GQI B;  4H34 A;  5EHR A;  4E93 A;  1O4Q A;  3C7I A;  4FBN A;  3VRZ A;  3VRO A;  1A09 A;  1WQU A;  4U17 A;  5GJI A;  2AOA A;  1SPR A;  2EL8 A;  2HDX A;  1UUS A;  2PLD A;  1O42 A;  4GPL B;  1SHD A;  1JYU A;  2RMX A;  3BUW B;  4LUE A;  1O4J A;  2PNB A;  1SHB A;  1O4M A;  1LCK A;  2QMS A;  3S9K A;  1O4L A;  2GE9 A;  1FYR A;  1UUR A;  1O4O A;  1SHA A;  5DC4 A;  2OZO A;  2XP1 A;  2MC1 A;  3CBL A;  2Y3A B;  1A07 A;  2LNX A;  3OB1 B;  2LQW A;  3PSK A;  1CSZ A;  1OPL A;  5HKZ A;  4GWF A;  2MRK A;  1JYR A;  3NHN A;  2IUI A;  1A1E A;  1FU5 A;  3VRP A;  1LUK A;  4OHH A;  2CRH A;  3M7F A;  1FMK A;  1FHS A;  2CI8 A;  2LQN A;  2YU7 A;  1O4R A;  2PTK A;  1B47 A;  2B3O A;  3HHM B;  4JGH A;  2PLE A;  1BF5 A;  2EOB A;  1A1B A;  2C0O A;  5EEQ A;  2EYY A;  3ZNI A;  1KSW A;  2RVF A;  3MXC A;  1A1A A;  4M4Z A;  3CD3 A;  1FU6 A;  3PFV A;  3VRN A;  4OHD A;  1BLJ A;  1R1Q A;  4WWQ A;  3VS7 A;  4F5B A;  1CSY A;  3PSJ A;  3HCK A;  3VRR A;  1O48 A;  3VGO A;  4FL2 A;  1SKJ A;  3VS2 A;  5CDW A;  5IBS A;  1LUM A;  4FL3 A;  1BKM A;  1O47 A;  2BBU A;  2H8H A;  5EEL A;  1X0N A;  1HCS B;  4OHE A;  1X6C A;  2Y1M A;  5DC9 A;  1GHU A;  1M27 A;  1NZV A;  2HDV A;  1Y1U A;  2CR4 A;  1R1P A;  2MK2 A;  2HCK A;  2EYZ A;  3PQZ A;  3PS5 A;  1LKK A;  4H1O A;  2CIA A;  3US4 A;  2AOB A;  5GJH A;  4GL9 E;  1JWO A;  5DF6 A;  1O4G A;  2ETZ A;  1LCJ A;  2YSX A;  3KFJ A;  1A1C A;  3VRY A;  4U1P A;  5I6V A;  3BUX B;  3TL0 A;  1D4T A;  1BMB A;  4K45 A;  3K2M A;  1AD5 A;  4D8K A;  1OPK A;  1MW4 A;  2CI9 A;  1AB2 A;  3OP0 A;  3VS1 A;  4K2R A;  3OV1 A;  2L6K A;  1R1S A;  5IBM A;  2EYV A;  1O4K A;  1KA6 A;  1O4P A;  2HMH A;  1O45 A;  2ECD A;  2PNA A;  2C0T A;  2SRC A;  1HCT B;  1IS0 A;  5KAZ A;  1AYA A;  4TZI A;  5EHP A;  1TCE A;  2DM0 A;  4XZ0 A;  3QWY A;  1LUN A;  1O4A A;  2H5K A;  1KC2 A;  1BHH A;  3OB2 B;  2GSB A;  3BUN B;  1Z3K A;  1RPY A;  2DCR A;  2EU0 A;  3GXX A;  4JE4 A;  2K7A B;  2ROR A;  1ZFP E;  3CWG A;  4P9Z A;  1NRV A;  2EO6 A;  1BM2 A;  2AUG A;  1CJ1 A;  1OO3 A;  4L1B B;  4DGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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