3S8LA

Protein-ligand interactions: thermodynamic effects associated with increasing hydrophobic surface area
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
101
structure length
101
Chain Sequence
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
pubmed doi rcsb
molecule tags Signaling protein/antagonist
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 22
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2011-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3s8lA00
3S8NA 2IUIA 4X6SA 1O46A 1Y1UA 3VRNA 2AOAA 1K9AA 2Y1MA 1M61A 3N8MA 2IUGA 3BUWB 3WA4A 1MW4A 5AXIA 2MQIA 3OB2B 2DX0A 3M7FA 1BHHA 4WWQA 1BMBA 1BG1A 3HIZB 1BHFA 2L6KA 1O4LA 3S9KA 3N7YA 3CXLA 3VGOA 1A1AA 2FCIA 2RMXA 1LUKA 1NZLA 5EEQA 1O4JA 1SHDA 2EOBA 3K2MA 4K45A 2DM0A 4ROJA 5DF6A 2EU0A 3IN8A 1H9OA 3BKBA 1O4IA 1KSWA 1A09A 2FO0A 3VRYA 2H8HA 3IMDA 1O47A 2GSBA 2RORA 1O4GA 4XZ0A 2ABLA 3TL0A 4NWGA 3VRZA 3HHMB 1O4PA 1O4FA 1AYAA 4JE4A 3ZNIA 2K7AB 1Z3KA 2EKXA 3PFVA 2IUHA 3S8LA 4DGXA 4F5BA 2CR4A 1O41A 1O4KA 2YU7A 1JYRA 1F2FA 2Y1NA 1FYRA 2HDVA 3IMJA 1QADA 4TZIA 1RPYA 4LUEA 1SKJA 3GXWA 2JYQA 1O4HA 1R1SA 4P9ZA 1BLKA 1X27A 1O4CA 1JWOA 1SHBA 3UF4A 1RJAA 1WQUA 1O43A 1A07A 1M27A 4JGHA 1KC2A 1NRVA 2VIFA 2DVJA 4F5AA 3OP0A 5DC0B 3CBLA 1CSZA 1KA7A 4NWFA 1BLJA 4OHIA 1O42A 2BBUA 3VROA 2DCRA 2CRHA 2OQ1A 1QCFA 1O4BA 2L3TA 2HMHA 2LCTA 1UURA 2B3OA 4OHDA 5D0JA 1O4OA 2GE9A 2HUWA 1O4MA 1AYDA 2EYZA 1HCTB 4FBNA 3PJPA 3NHNA 2DLZA 4OHHA 4GL9E 2SHPA 3PS5A 1IS0A 1FBZA 1NZVA 3BUMB 2PNAA 4JEGA 5EG3B 1X6CA 1BFJA 1TZEE 1LUNA 1BKMA 1AD5A 1CJ1A 1D4WA 1JYUA 4P9VA 1O4RA 3TKZA 1HCSB 1OO4A 1LUMA 3PSJA 2MRJA 1O4QA 2SRCA 3VRRA 2EYVA 2LNXA 1B47A 4L1BB 2LNWA 3EAZA 1FBVA 3US4A 3VS1A 2KK6A 2HDXA 2QMSA 2IZVA 1SPRA 3VRPA 2PLDA 2H46E 3QWYA 1MILA 1OPLA 3PLFB 4D8KA 2C0IA 1BKLA 1BM2A 3EACA 4LUDA 4EIHA 3MAZA 1BHHB 2H5KA 2ECDA 3MXYA 1UUSA 5I6VA 1CWDL 1JU5A 1O49A 1LCJA 2AOBA 1IJRA 4EY0A 1G83A 1A81A 4OHEA 2C0OA 3VS5A 4A4CA 3IN7A 1AYBA 1FMKA 2KNOA 3VS0A 1F1WA 2AUGA 1O4EA 2EO3A 1AYCA 3VS6A 3VS4A 1OO3A 1X0NA 4DGPA 5GJIA 1R1QA 2MK2A 2HCKA 2C0TA 3BUXB 1A1CA 1D1ZA 3C7IA 1D4TA 1Y57A 3OV1A 2ETZA 4M4ZA 3CWGA 1QG1E 1FU6A 4XZ1A 2L4KA 2C9WA 1YVHA 3S8OA 3GQIB 3VS7A 2PTKA 3PSKA 5IBMA 2DLYA 2OZOA 4F59A 1LUIA 1JYQA 1O4AA 5AULA 1FU5A 1A1BA 2CIAA 5EHRA 2CI9A 1O44A 1LCKA 1BFIA 2LQWA 1XA6A 5DC9A 1TCEA 1GHUA 1GRIA 4K44A 1LKKA 3KFJA 1O48A 1AOTF 1A08A 2CBLA 3PQZA 2EYYA 1I3ZA 3OVEA 1YVLA 3CD3A 4H1OA 4GWFA 5J3XA 1ZFPE 1OPKA 2MC1A 3N84A 5DC4A 3BUNB 3T04A 1SHAA 3QWXX 1SPSA 2RSYA 5KAZA 4H34A 2YSXA 4K2RA 2MRKA 1LKLA 2XP1A 4E93A 1P13A 2K79B 5GJHA 1RQQC 4U17A 1BF5A 3OB1B 1O4DA 4U1PA 3VS3A 2LQNA 3VS2A 4A4BA 5HKWA 1A1EA 1CWEA 2EL8A 2CI8A 3GXXA 5EELA 2RVFA 5HKYA 1PICA 5IBSA 3VRQA 4FL2A 3UYOA 4GPLB 3MXCA 1R1PA 2PLEA 4E68A 5HKZA 2Y3AB 4K11A 1AOUF 2PNBA 1FHSA 1O45A 5CDWA 5EHPA 3HCKA 1AB2A 1KA6A 1CSYA 2EO6A 3BUOB 2CS0A 4OHLA 4QSYA 4FL3A 5BO4A 1O4NA
chains in the Genus database with same CATH superfamily
3S8NA 2IUIA 4X6SA 1O46A 1Y1UA 3VRNA 2AOAA 1K9AA 2Y1MA 1M61A 3N8MA 2IUGA 3BUWB 3WA4A 1MW4A 5AXIA 2MQIA 3OB2B 2DX0A 3M7FA 1BHHA 4WWQA 1BMBA 1BG1A 3HIZB 1BHFA 2L6KA 1O4LA 3S9KA 3N7YA 3CXLA 3VGOA 1A1AA 2FCIA 2RMXA 1LUKA 1NZLA 5EEQA 1O4JA 1SHDA 2EOBA 3K2MA 4K45A 2DM0A 4ROJA 5DF6A 2EU0A 3IN8A 1H9OA 3BKBA 1O4IA 1KSWA 1A09A 2FO0A 3VRYA 2H8HA 3IMDA 1O47A 2GSBA 2RORA 1O4GA 4XZ0A 2ABLA 3TL0A 4NWGA 3VRZA 3HHMB 1O4PA 1O4FA 1AYAA 4JE4A 3ZNIA 2K7AB 1Z3KA 2EKXA 3PFVA 2IUHA 3S8LA 4DGXA 4F5BA 2CR4A 1O41A 1O4KA 2YU7A 1JYRA 1F2FA 2Y1NA 1FYRA 2HDVA 3IMJA 1QADA 4TZIA 1RPYA 4LUEA 1SKJA 3GXWA 2JYQA 1O4HA 1R1SA 4P9ZA 1BLKA 1X27A 1O4CA 1JWOA 1SHBA 3UF4A 1RJAA 1WQUA 1O43A 1A07A 1M27A 4JGHA 1KC2A 1NRVA 2VIFA 2DVJA 4F5AA 3OP0A 5DC0B 3CBLA 1CSZA 1KA7A 4NWFA 1BLJA 4OHIA 1O42A 2BBUA 3VROA 2DCRA 2CRHA 2OQ1A 1QCFA 1O4BA 2L3TA 2HMHA 2LCTA 1UURA 2B3OA 4OHDA 5D0JA 1O4OA 2GE9A 2HUWA 1O4MA 1AYDA 2EYZA 1HCTB 4FBNA 3PJPA 2KGYA 3NHNA 2DLZA 4OHHA 4GL9E 2SHPA 3PS5A 1IS0A 1FBZA 1NZVA 3BUMB 2PNAA 4JEGA 5EG3B 1X6CA 1BFJA 1TZEE 1LUNA 1BKMA 1AD5A 1CJ1A 1D4WA 1JYUA 4P9VA 1O4RA 3TKZA 1HCSB 1OO4A 1LUMA 3PSJA 2MRJA 1O4QA 2SRCA 3VRRA 2EYVA 2LNXA 1B47A 4L1BB 2LNWA 3EAZA 1FBVA 3US4A 3VS1A 2KK6A 2HDXA 2QMSA 2IZVA 1SPRA 3VRPA 2PLDA 2H46E 3QWYA 1MILA 1OPLA 3PLFB 4D8KA 2C0IA 1BKLA 1BM2A 3EACA 4LUDA 4EIHA 3MAZA 1BHHB 2H5KA 2ECDA 3MXYA 1UUSA 5I6VA 1CWDL 1JU5A 1O49A 1LCJA 2AOBA 1IJRA 4EY0A 1G83A 1A81A 4OHEA 2C0OA 3VS5A 4A4CA 3IN7A 1AYBA 1FMKA 2KNOA 3VS0A 1F1WA 2AUGA 1O4EA 2EO3A 1AYCA 3VS6A 3VS4A 1OO3A 1X0NA 4DGPA 5GJIA 1R1QA 2MK2A 2HCKA 2C0TA 3BUXB 1A1CA 1D1ZA 3C7IA 1D4TA 1Y57A 3OV1A 2ETZA 4M4ZA 3CWGA 1QG1E 1FU6A 4XZ1A 2L4KA 2C9WA 1YVHA 3S8OA 3GQIB 3VS7A 2PTKA 3PSKA 5IBMA 2DLYA 2OZOA 4F59A 1LUIA 1JYQA 1O4AA 5AULA 1FU5A 1A1BA 2CIAA 5EHRA 2CI9A 1O44A 1LCKA 1BFIA 2LQWA 1XA6A 5DC9A 1TCEA 1GHUA 1GRIA 4K44A 1LKKA 3KFJA 1O48A 1AOTF 1A08A 2CBLA 3PQZA 2EYYA 1I3ZA 3OVEA 1YVLA 3CD3A 4H1OA 4GWFA 5J3XA 1ZFPE 1OPKA 2MC1A 3N84A 5DC4A 3BUNB 3T04A 1SHAA 3QWXX 1SPSA 2RSYA 5KAZA 4H34A 2YSXA 4K2RA 2LRAA 1LKLA 2MRKA 2XP1A 4E93A 1P13A 2K79B 5GJHA 1RQQC 4U17A 1BF5A 3OB1B 1O4DA 4U1PA 3VS3A 2LQNA 3VS2A 4A4BA 5HKWA 3K2TA 1A1EA 1CWEA 2EL8A 2CI8A 3GXXA 5EELA 2RVFA 5HKYA 1PICA 5IBSA 3LYVA 3VRQA 4FL2A 3UYOA 4GPLB 3MXCA 1R1PA 2PLEA 4E68A 5HKZA 2Y3AB 4K11A 1AOUF 2PNBA 1FHSA 1O45A 5CDWA 5EHPA 3HCKA 1AB2A 1KA6A 1CSYA 2EO6A 3BUOB 2CS0A 4OHLA 4QSYA 4FL3A 5BO4A 1O4NA
chains in the Genus database with same CATH topology
3S8NA 2IUIA 4X6SA 1O46A 1Y1UA 3VRNA 2AOAA 1K9AA 2Y1MA 1M61A 3N8MA 2IUGA 3BUWB 3WA4A 1MW4A 5AXIA 2MQIA 3OB2B 2DX0A 3M7FA 1BHHA 4WWQA 1BMBA 1BG1A 3HIZB 1BHFA 2L6KA 1O4LA 3S9KA 3N7YA 3CXLA 3VGOA 1A1AA 2FCIA 2RMXA 1LUKA 1NZLA 5EEQA 1O4JA 1SHDA 2EOBA 3K2MA 4K45A 2DM0A 4ROJA 5DF6A 2EU0A 3IN8A 1H9OA 3BKBA 1O4IA 1KSWA 1A09A 2FO0A 3VRYA 2H8HA 3IMDA 1O47A 2GSBA 2RORA 1O4GA 4XZ0A 2ABLA 3TL0A 4NWGA 3VRZA 3HHMB 1O4PA 1O4FA 1AYAA 4JE4A 3ZNIA 2K7AB 1Z3KA 2EKXA 3PFVA 2IUHA 3S8LA 4DGXA 4F5BA 2CR4A 1O41A 1O4KA 2YU7A 1JYRA 1F2FA 2Y1NA 1FYRA 2HDVA 3IMJA 1QADA 4TZIA 1RPYA 4LUEA 1SKJA 3GXWA 2JYQA 1O4HA 1R1SA 4P9ZA 1BLKA 1X27A 1O4CA 1JWOA 1SHBA 3UF4A 1RJAA 1WQUA 1O43A 1A07A 1M27A 4JGHA 1KC2A 1NRVA 2VIFA 2DVJA 4F5AA 3OP0A 5DC0B 3CBLA 1CSZA 1KA7A 4NWFA 1BLJA 4OHIA 1O42A 2BBUA 3VROA 2DCRA 2CRHA 2OQ1A 1QCFA 1O4BA 2L3TA 2HMHA 2LCTA 1UURA 2B3OA 4OHDA 5D0JA 1O4OA 2GE9A 2HUWA 1O4MA 1AYDA 2EYZA 1HCTB 4FBNA 3PJPA 3NHNA 2DLZA 4OHHA 4GL9E 2SHPA 3PS5A 1IS0A 1FBZA 1NZVA 3BUMB 2PNAA 4JEGA 5EG3B 1X6CA 1BFJA 1TZEE 1LUNA 1BKMA 1AD5A 1CJ1A 1D4WA 1JYUA 4P9VA 1O4RA 3TKZA 1HCSB 1OO4A 1LUMA 3PSJA 2MRJA 1O4QA 2SRCA 3VRRA 2EYVA 2LNXA 1B47A 4L1BB 2LNWA 3EAZA 1FBVA 3US4A 3VS1A 2KK6A 2HDXA 2QMSA 2IZVA 1SPRA 3VRPA 2PLDA 2H46E 3QWYA 1MILA 1OPLA 3PLFB 4D8KA 2C0IA 1BKLA 1BM2A 3EACA 4LUDA 4EIHA 3MAZA 1BHHB 2H5KA 2ECDA 3MXYA 1UUSA 5I6VA 1CWDL 1JU5A 1O49A 1LCJA 2AOBA 1IJRA 4EY0A 1G83A 1A81A 4OHEA 2C0OA 3VS5A 4A4CA 3IN7A 1AYBA 1FMKA 2KNOA 3VS0A 1F1WA 2AUGA 1O4EA 2EO3A 1AYCA 3VS6A 3VS4A 1OO3A 1X0NA 4DGPA 5GJIA 1R1QA 2MK2A 2HCKA 2C0TA 3BUXB 1A1CA 1D1ZA 3C7IA 1D4TA 1Y57A 3OV1A 2ETZA 4M4ZA 3CWGA 1QG1E 1FU6A 4XZ1A 2L4KA 2C9WA 1YVHA 3S8OA 3GQIB 3VS7A 2PTKA 3PSKA 5IBMA 2DLYA 2OZOA 4F59A 1LUIA 1JYQA 1O4AA 5AULA 1FU5A 1A1BA 2CIAA 5EHRA 2CI9A 1O44A 1LCKA 1BFIA 2LQWA 1XA6A 5DC9A 1TCEA 1GHUA 1GRIA 4K44A 1LKKA 3KFJA 1O48A 1AOTF 1A08A 2CBLA 3PQZA 2EYYA 1I3ZA 3OVEA 1YVLA 3CD3A 4H1OA 4GWFA 5J3XA 1ZFPE 1OPKA 2MC1A 3N84A 5DC4A 3BUNB 3T04A 1SHAA 3QWXX 1SPSA 2RSYA 5KAZA 4H34A 2YSXA 4K2RA 2MRKA 1LKLA 2XP1A 4E93A 1P13A 2K79B 5GJHA 1RQQC 4U17A 1BF5A 3OB1B 1O4DA 4U1PA 3VS3A 2LQNA 3VS2A 4A4BA 5HKWA 1A1EA 1CWEA 2EL8A 2CI8A 3GXXA 5EELA 2RVFA 5HKYA 1PICA 5IBSA 3VRQA 4FL2A 3UYOA 4GPLB 3MXCA 1R1PA 2PLEA 4E68A 5HKZA 2Y3AB 4K11A 1AOUF 2PNBA 1FHSA 1O45A 5CDWA 5EHPA 3HCKA 1AB2A 1KA6A 1CSYA 2EO6A 3BUOB 2CS0A 4OHLA 4QSYA 4FL3A 5BO4A 1O4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S8N A;  2IUI A;  4X6S A;  1O46 A;  1Y1U A;  3VRN A;  2AOA A;  1K9A A;  2Y1M A;  1M61 A;  3N8M A;  2IUG A;  3BUW B;  3WA4 A;  1MW4 A;  5AXI A;  2MQI A;  3OB2 B;  2DX0 A;  3M7F A;  1BHH A;  4WWQ A;  1BMB A;  1BG1 A;  3HIZ B;  1BHF A;  2L6K A;  1O4L A;  3S9K A;  3N7Y A;  3CXL A;  3VGO A;  1A1A A;  2FCI A;  2RMX A;  1LUK A;  1NZL A;  5EEQ A;  1O4J A;  1SHD A;  2EOB A;  3K2M A;  4K45 A;  2DM0 A;  4ROJ A;  5DF6 A;  2EU0 A;  3IN8 A;  1H9O A;  3BKB A;  1O4I A;  1KSW A;  1A09 A;  2FO0 A;  3VRY A;  2H8H A;  3IMD A;  1O47 A;  2GSB A;  2ROR A;  1O4G A;  4XZ0 A;  2ABL A;  3TL0 A;  4NWG A;  3VRZ A;  3HHM B;  1O4P A;  1O4F A;  1AYA A;  4JE4 A;  3ZNI A;  2K7A B;  1Z3K A;  2EKX A;  3PFV A;  2IUH A;  3S8L A;  4DGX A;  4F5B A;  2CR4 A;  1O41 A;  1O4K A;  2YU7 A;  1JYR A;  1F2F A;  2Y1N A;  1FYR A;  2HDV A;  3IMJ A;  1QAD A;  4TZI A;  1RPY A;  4LUE A;  1SKJ A;  3GXW A;  2JYQ A;  1O4H A;  1R1S A;  4P9Z A;  1BLK A;  1X27 A;  1O4C A;  1JWO A;  1SHB A;  3UF4 A;  1RJA A;  1WQU A;  1O43 A;  1A07 A;  1M27 A;  4JGH A;  1KC2 A;  1NRV A;  2VIF A;  2DVJ A;  4F5A A;  3OP0 A;  5DC0 B;  3CBL A;  1CSZ A;  1KA7 A;  4NWF A;  1BLJ A;  4OHI A;  1O42 A;  2BBU A;  3VRO A;  2DCR A;  2CRH A;  2OQ1 A;  1QCF A;  1O4B A;  2L3T A;  2HMH A;  2LCT A;  1UUR A;  2B3O A;  4OHD A;  5D0J A;  1O4O A;  2GE9 A;  2HUW A;  1O4M A;  1AYD A;  2EYZ A;  1HCT B;  4FBN A;  3PJP A;  3NHN A;  2DLZ A;  4OHH A;  4GL9 E;  2SHP A;  3PS5 A;  1IS0 A;  1FBZ A;  1NZV A;  3BUM B;  2PNA A;  4JEG A;  5EG3 B;  1X6C A;  1BFJ A;  1TZE E;  1LUN A;  1BKM A;  1AD5 A;  1CJ1 A;  1D4W A;  1JYU A;  4P9V A;  1O4R A;  3TKZ A;  1HCS B;  1OO4 A;  1LUM A;  3PSJ A;  2MRJ A;  1O4Q A;  2SRC A;  3VRR A;  2EYV A;  2LNX A;  1B47 A;  4L1B B;  2LNW A;  3EAZ A;  1FBV A;  3US4 A;  3VS1 A;  2KK6 A;  2HDX A;  2QMS A;  2IZV A;  1SPR A;  3VRP A;  2PLD A;  2H46 E;  3QWY A;  1MIL A;  1OPL A;  3PLF B;  4D8K A;  2C0I A;  1BKL A;  1BM2 A;  3EAC A;  4LUD A;  4EIH A;  3MAZ A;  1BHH B;  2H5K A;  2ECD A;  3MXY A;  1UUS A;  5I6V A;  1CWD L;  1JU5 A;  1O49 A;  1LCJ A;  2AOB A;  1IJR A;  4EY0 A;  1G83 A;  1A81 A;  4OHE A;  2C0O A;  3VS5 A;  4A4C A;  3IN7 A;  1AYB A;  1FMK A;  2KNO A;  3VS0 A;  1F1W A;  2AUG A;  1O4E A;  2EO3 A;  1AYC A;  3VS6 A;  3VS4 A;  1OO3 A;  1X0N A;  4DGP A;  5GJI A;  1R1Q A;  2MK2 A;  2HCK A;  2C0T A;  3BUX B;  1A1C A;  1D1Z A;  3C7I A;  1D4T A;  1Y57 A;  3OV1 A;  2ETZ A;  4M4Z A;  3CWG A;  1QG1 E;  1FU6 A;  4XZ1 A;  2L4K A;  2C9W A;  1YVH A;  3S8O A;  3GQI B;  3VS7 A;  2PTK A;  3PSK A;  5IBM A;  2DLY A;  2OZO A;  4F59 A;  1LUI A;  1JYQ A;  1O4A A;  5AUL A;  1FU5 A;  1A1B A;  2CIA A;  5EHR A;  2CI9 A;  1O44 A;  1LCK A;  1BFI A;  2LQW A;  1XA6 A;  5DC9 A;  1TCE A;  1GHU A;  1GRI A;  4K44 A;  1LKK A;  3KFJ A;  1O48 A;  1AOT F;  1A08 A;  2CBL A;  3PQZ A;  2EYY A;  1I3Z A;  3OVE A;  1YVL A;  3CD3 A;  4H1O A;  4GWF A;  5J3X A;  1ZFP E;  1OPK A;  2MC1 A;  3N84 A;  5DC4 A;  3BUN B;  3T04 A;  1SHA A;  3QWX X;  1SPS A;  2RSY A;  5KAZ A;  4H34 A;  2YSX A;  4K2R A;  2MRK A;  1LKL A;  2XP1 A;  4E93 A;  1P13 A;  2K79 B;  5GJH A;  1RQQ C;  4U17 A;  1BF5 A;  3OB1 B;  1O4D A;  4U1P A;  3VS3 A;  2LQN A;  3VS2 A;  4A4B A;  5HKW A;  1A1E A;  1CWE A;  2EL8 A;  2CI8 A;  3GXX A;  5EEL A;  2RVF A;  5HKY A;  1PIC A;  5IBS A;  3VRQ A;  4FL2 A;  3UYO A;  4GPL B;  3MXC A;  1R1P A;  2PLE A;  4E68 A;  5HKZ A;  2Y3A B;  4K11 A;  1AOU F;  2PNB A;  1FHS A;  1O45 A;  5CDW A;  5EHP A;  3HCK A;  1AB2 A;  1KA6 A;  1CSY A;  2EO6 A;  3BUO B;  2CS0 A;  4OHL A;  4QSY A;  4FL3 A;  5BO4 A;  1O4N A; 
#chains in the Genus database with same CATH topology
 3S8N A;  2IUI A;  4X6S A;  1O46 A;  1Y1U A;  3VRN A;  2AOA A;  1K9A A;  2Y1M A;  1M61 A;  3N8M A;  2IUG A;  3BUW B;  3WA4 A;  1MW4 A;  5AXI A;  2MQI A;  3OB2 B;  2DX0 A;  3M7F A;  1BHH A;  4WWQ A;  1BMB A;  1BG1 A;  3HIZ B;  1BHF A;  2L6K A;  1O4L A;  3S9K A;  3N7Y A;  3CXL A;  3VGO A;  1A1A A;  2FCI A;  2RMX A;  1LUK A;  1NZL A;  5EEQ A;  1O4J A;  1SHD A;  2EOB A;  3K2M A;  4K45 A;  2DM0 A;  4ROJ A;  5DF6 A;  2EU0 A;  3IN8 A;  1H9O A;  3BKB A;  1O4I A;  1KSW A;  1A09 A;  2FO0 A;  3VRY A;  2H8H A;  3IMD A;  1O47 A;  2GSB A;  2ROR A;  1O4G A;  4XZ0 A;  2ABL A;  3TL0 A;  4NWG A;  3VRZ A;  3HHM B;  1O4P A;  1O4F A;  1AYA A;  4JE4 A;  3ZNI A;  2K7A B;  1Z3K A;  2EKX A;  3PFV A;  2IUH A;  3S8L A;  4DGX A;  4F5B A;  2CR4 A;  1O41 A;  1O4K A;  2YU7 A;  1JYR A;  1F2F A;  2Y1N A;  1FYR A;  2HDV A;  3IMJ A;  1QAD A;  4TZI A;  1RPY A;  4LUE A;  1SKJ A;  3GXW A;  2JYQ A;  1O4H A;  1R1S A;  4P9Z A;  1BLK A;  1X27 A;  1O4C A;  1JWO A;  1SHB A;  3UF4 A;  1RJA A;  1WQU A;  1O43 A;  1A07 A;  1M27 A;  4JGH A;  1KC2 A;  1NRV A;  2VIF A;  2DVJ A;  4F5A A;  3OP0 A;  5DC0 B;  3CBL A;  1CSZ A;  1KA7 A;  4NWF A;  1BLJ A;  4OHI A;  1O42 A;  2BBU A;  3VRO A;  2DCR A;  2CRH A;  2OQ1 A;  1QCF A;  1O4B A;  2L3T A;  2HMH A;  2LCT A;  1UUR A;  2B3O A;  4OHD A;  5D0J A;  1O4O A;  2GE9 A;  2HUW A;  1O4M A;  1AYD A;  2EYZ A;  1HCT B;  4FBN A;  3PJP A;  2KGY A;  3NHN A;  2DLZ A;  4OHH A;  4GL9 E;  2SHP A;  3PS5 A;  1IS0 A;  1FBZ A;  1NZV A;  3BUM B;  2PNA A;  4JEG A;  5EG3 B;  1X6C A;  1BFJ A;  1TZE E;  1LUN A;  1BKM A;  1AD5 A;  1CJ1 A;  1D4W A;  1JYU A;  4P9V A;  1O4R A;  3TKZ A;  1HCS B;  1OO4 A;  1LUM A;  3PSJ A;  2MRJ A;  1O4Q A;  2SRC A;  3VRR A;  2EYV A;  2LNX A;  1B47 A;  4L1B B;  2LNW A;  3EAZ A;  1FBV A;  3US4 A;  3VS1 A;  2KK6 A;  2HDX A;  2QMS A;  2IZV A;  1SPR A;  3VRP A;  2PLD A;  2H46 E;  3QWY A;  1MIL A;  1OPL A;  3PLF B;  4D8K A;  2C0I A;  1BKL A;  1BM2 A;  3EAC A;  4LUD A;  4EIH A;  3MAZ A;  1BHH B;  2H5K A;  2ECD A;  3MXY A;  1UUS A;  5I6V A;  1CWD L;  1JU5 A;  1O49 A;  1LCJ A;  2AOB A;  1IJR A;  4EY0 A;  1G83 A;  1A81 A;  4OHE A;  2C0O A;  3VS5 A;  4A4C A;  3IN7 A;  1AYB A;  1FMK A;  2KNO A;  3VS0 A;  1F1W A;  2AUG A;  1O4E A;  2EO3 A;  1AYC A;  3VS6 A;  3VS4 A;  1OO3 A;  1X0N A;  4DGP A;  5GJI A;  1R1Q A;  2MK2 A;  2HCK A;  2C0T A;  3BUX B;  1A1C A;  1D1Z A;  3C7I A;  1D4T A;  1Y57 A;  3OV1 A;  2ETZ A;  4M4Z A;  3CWG A;  1QG1 E;  1FU6 A;  4XZ1 A;  2L4K A;  2C9W A;  1YVH A;  3S8O A;  3GQI B;  3VS7 A;  2PTK A;  3PSK A;  5IBM A;  2DLY A;  2OZO A;  4F59 A;  1LUI A;  1JYQ A;  1O4A A;  5AUL A;  1FU5 A;  1A1B A;  2CIA A;  5EHR A;  2CI9 A;  1O44 A;  1LCK A;  1BFI A;  2LQW A;  1XA6 A;  5DC9 A;  1TCE A;  1GHU A;  1GRI A;  4K44 A;  1LKK A;  3KFJ A;  1O48 A;  1AOT F;  1A08 A;  2CBL A;  3PQZ A;  2EYY A;  1I3Z A;  3OVE A;  1YVL A;  3CD3 A;  4H1O A;  4GWF A;  5J3X A;  1ZFP E;  1OPK A;  2MC1 A;  3N84 A;  5DC4 A;  3BUN B;  3T04 A;  1SHA A;  3QWX X;  1SPS A;  2RSY A;  5KAZ A;  4H34 A;  2YSX A;  4K2R A;  2LRA A;  1LKL A;  2MRK A;  2XP1 A;  4E93 A;  1P13 A;  2K79 B;  5GJH A;  1RQQ C;  4U17 A;  1BF5 A;  3OB1 B;  1O4D A;  4U1P A;  3VS3 A;  2LQN A;  3VS2 A;  4A4B A;  5HKW A;  3K2T A;  1A1E A;  1CWE A;  2EL8 A;  2CI8 A;  3GXX A;  5EEL A;  2RVF A;  5HKY A;  1PIC A;  5IBS A;  3LYV A;  3VRQ A;  4FL2 A;  3UYO A;  4GPL B;  3MXC A;  1R1P A;  2PLE A;  4E68 A;  5HKZ A;  2Y3A B;  4K11 A;  1AOU F;  2PNB A;  1FHS A;  1O45 A;  5CDW A;  5EHP A;  3HCK A;  1AB2 A;  1KA6 A;  1CSY A;  2EO6 A;  3BUO B;  2CS0 A;  4OHL A;  4QSY A;  4FL3 A;  5BO4 A;  1O4N A; 
#chains in the Genus database with same CATH homology
 3S8N A;  2IUI A;  4X6S A;  1O46 A;  1Y1U A;  3VRN A;  2AOA A;  1K9A A;  2Y1M A;  1M61 A;  3N8M A;  2IUG A;  3BUW B;  3WA4 A;  1MW4 A;  5AXI A;  2MQI A;  3OB2 B;  2DX0 A;  3M7F A;  1BHH A;  4WWQ A;  1BMB A;  1BG1 A;  3HIZ B;  1BHF A;  2L6K A;  1O4L A;  3S9K A;  3N7Y A;  3CXL A;  3VGO A;  1A1A A;  2FCI A;  2RMX A;  1LUK A;  1NZL A;  5EEQ A;  1O4J A;  1SHD A;  2EOB A;  3K2M A;  4K45 A;  2DM0 A;  4ROJ A;  5DF6 A;  2EU0 A;  3IN8 A;  1H9O A;  3BKB A;  1O4I A;  1KSW A;  1A09 A;  2FO0 A;  3VRY A;  2H8H A;  3IMD A;  1O47 A;  2GSB A;  2ROR A;  1O4G A;  4XZ0 A;  2ABL A;  3TL0 A;  4NWG A;  3VRZ A;  3HHM B;  1O4P A;  1O4F A;  1AYA A;  4JE4 A;  3ZNI A;  2K7A B;  1Z3K A;  2EKX A;  3PFV A;  2IUH A;  3S8L A;  4DGX A;  4F5B A;  2CR4 A;  1O41 A;  1O4K A;  2YU7 A;  1JYR A;  1F2F A;  2Y1N A;  1FYR A;  2HDV A;  3IMJ A;  1QAD A;  4TZI A;  1RPY A;  4LUE A;  1SKJ A;  3GXW A;  2JYQ A;  1O4H A;  1R1S A;  4P9Z A;  1BLK A;  1X27 A;  1O4C A;  1JWO A;  1SHB A;  3UF4 A;  1RJA A;  1WQU A;  1O43 A;  1A07 A;  1M27 A;  4JGH A;  1KC2 A;  1NRV A;  2VIF A;  2DVJ A;  4F5A A;  3OP0 A;  5DC0 B;  3CBL A;  1CSZ A;  1KA7 A;  4NWF A;  1BLJ A;  4OHI A;  1O42 A;  2BBU A;  3VRO A;  2DCR A;  2CRH A;  2OQ1 A;  1QCF A;  1O4B A;  2L3T A;  2HMH A;  2LCT A;  1UUR A;  2B3O A;  4OHD A;  5D0J A;  1O4O A;  2GE9 A;  2HUW A;  1O4M A;  1AYD A;  2EYZ A;  1HCT B;  4FBN A;  3PJP A;  3NHN A;  2DLZ A;  4OHH A;  4GL9 E;  2SHP A;  3PS5 A;  1IS0 A;  1FBZ A;  1NZV A;  3BUM B;  2PNA A;  4JEG A;  5EG3 B;  1X6C A;  1BFJ A;  1TZE E;  1LUN A;  1BKM A;  1AD5 A;  1CJ1 A;  1D4W A;  1JYU A;  4P9V A;  1O4R A;  3TKZ A;  1HCS B;  1OO4 A;  1LUM A;  3PSJ A;  2MRJ A;  1O4Q A;  2SRC A;  3VRR A;  2EYV A;  2LNX A;  1B47 A;  4L1B B;  2LNW A;  3EAZ A;  1FBV A;  3US4 A;  3VS1 A;  2KK6 A;  2HDX A;  2QMS A;  2IZV A;  1SPR A;  3VRP A;  2PLD A;  2H46 E;  3QWY A;  1MIL A;  1OPL A;  3PLF B;  4D8K A;  2C0I A;  1BKL A;  1BM2 A;  3EAC A;  4LUD A;  4EIH A;  3MAZ A;  1BHH B;  2H5K A;  2ECD A;  3MXY A;  1UUS A;  5I6V A;  1CWD L;  1JU5 A;  1O49 A;  1LCJ A;  2AOB A;  1IJR A;  4EY0 A;  1G83 A;  1A81 A;  4OHE A;  2C0O A;  3VS5 A;  4A4C A;  3IN7 A;  1AYB A;  1FMK A;  2KNO A;  3VS0 A;  1F1W A;  2AUG A;  1O4E A;  2EO3 A;  1AYC A;  3VS6 A;  3VS4 A;  1OO3 A;  1X0N A;  4DGP A;  5GJI A;  1R1Q A;  2MK2 A;  2HCK A;  2C0T A;  3BUX B;  1A1C A;  1D1Z A;  3C7I A;  1D4T A;  1Y57 A;  3OV1 A;  2ETZ A;  4M4Z A;  3CWG A;  1QG1 E;  1FU6 A;  4XZ1 A;  2L4K A;  2C9W A;  1YVH A;  3S8O A;  3GQI B;  3VS7 A;  2PTK A;  3PSK A;  5IBM A;  2DLY A;  2OZO A;  4F59 A;  1LUI A;  1JYQ A;  1O4A A;  5AUL A;  1FU5 A;  1A1B A;  2CIA A;  5EHR A;  2CI9 A;  1O44 A;  1LCK A;  1BFI A;  2LQW A;  1XA6 A;  5DC9 A;  1TCE A;  1GHU A;  1GRI A;  4K44 A;  1LKK A;  3KFJ A;  1O48 A;  1AOT F;  1A08 A;  2CBL A;  3PQZ A;  2EYY A;  1I3Z A;  3OVE A;  1YVL A;  3CD3 A;  4H1O A;  4GWF A;  5J3X A;  1ZFP E;  1OPK A;  2MC1 A;  3N84 A;  5DC4 A;  3BUN B;  3T04 A;  1SHA A;  3QWX X;  1SPS A;  2RSY A;  5KAZ A;  4H34 A;  2YSX A;  4K2R A;  2MRK A;  1LKL A;  2XP1 A;  4E93 A;  1P13 A;  2K79 B;  5GJH A;  1RQQ C;  4U17 A;  1BF5 A;  3OB1 B;  1O4D A;  4U1P A;  3VS3 A;  2LQN A;  3VS2 A;  4A4B A;  5HKW A;  1A1E A;  1CWE A;  2EL8 A;  2CI8 A;  3GXX A;  5EEL A;  2RVF A;  5HKY A;  1PIC A;  5IBS A;  3VRQ A;  4FL2 A;  3UYO A;  4GPL B;  3MXC A;  1R1P A;  2PLE A;  4E68 A;  5HKZ A;  2Y3A B;  4K11 A;  1AOU F;  2PNB A;  1FHS A;  1O45 A;  5CDW A;  5EHP A;  3HCK A;  1AB2 A;  1KA6 A;  1CSY A;  2EO6 A;  3BUO B;  2CS0 A;  4OHL A;  4QSY A;  4FL3 A;  5BO4 A;  1O4N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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