3S8LA

Protein-ligand interactions: thermodynamic effects associated with increasing hydrophobic surface area
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
101
structure length
101
Chain Sequence
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
pubmed doi rcsb
molecule tags Signaling protein/antagonist
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 22
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2011-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3s8lA00
1CJ1A 1O4CA 2LQNA 2EYZA 1YVHA 3NHNA 2H5KA 3OB2B 1HCSB 1O4NA 1SPSA 1YVLA 5HKZA 1AYCA 4LUEA 1O46A 2FCIA 1JYQA 2HCKA 3VRPA 3IN7A 1LKKA 2YSXA 4GPLB 4EY0A 3UYOA 1FU5A 1GRIA 1TZEE 3N8MA 1OPKA 3US4A 1CWEA 3TL0A 1O47A 1RPYA 5IBSA 4F5BA 1O4OA 2VIFA 1LUKA 1O4BA 3VS3A 1O45A 2LCTA 2EYVA 2DVJA 2IUIA 4OHIA 1BM2A 2EYYA 3VRRA 3OP0A 1O48A 1QADA 4K44A 4XZ0A 1JYUA 4P9ZA 4JGHA 2PNBA 2C0OA 1A1CA 1R1QA 1A07A 5DC9A 3VS6A 1UURA 1M27A 2RORA 2IZVA 2RMXA 1M61A 2DCRA 3VS2A 3OV1A 1O4IA 2HDVA 3OB1B 5EELA 1AOUF 1A09A 2KNOA 2QMSA 5GJIA 1I3ZA 1BHFA 1A1EA 1MW4A 3S8NA 3VRZA 2CBLA 2EKXA 1BFJA 1QG1E 5EHPA 2L6KA 1BHHB 1FBVA 5J3XA 1LKLA 2EU0A 1AYBA 3PFVA 3GQIB 2MQIA 3VS0A 5DF6A 2SRCA 3VRNA 1FMKA 5CDWA 3EAZA 3BUMB 2GSBA 3BUNB 2HUWA 1A08A 1B47A 1O4RA 4EIHA 3S9KA 3GXWA 1F1WA 2OQ1A 1F2FA 1O4AA 1IS0A 1UUSA 1D1ZA 4OHLA 4U17A 5BO4A 2PTKA 3MAZA 3MXCA 4QSYA 1BKLA 1GHUA 5AULA 2RSYA 4GWFA 1CWDL 1NZLA 1A81A 5EG3B 1AB2A 1O4KA 1BMBA 2CR4A 5KAZA 3CWGA 1O4FA 4M4ZA 1SHBA 3QWXX 3M7FA 4NWFA 1BF5A 1X6CA 4JEGA 2K79B 4XZ1A 3BKBA 3VS4A 4D8KA 4JE4A 1O4PA 2CI9A 1JYRA 1FYRA 1BG1A 2DM0A 2PNAA 1Z3KA 1H9OA 2H8HA 2HMHA 2PLDA 3BUWB 4K11A 1FHSA 3CXLA 2ABLA 1SHDA 2PLEA 2C9WA 4DGXA 1IJRA 4K45A 3MXYA 3S8LA 1BHHA 3PSKA 1TCEA 1ZFPE 2SHPA 2EOBA 1AD5A 1X0NA 2AOAA 3QWYA 3HCKA 2JYQA 4H34A 2C0IA 1O4JA 1O41A 1BLKA 4OHHA 5I6VA 1NZVA 3IMJA 4A4BA 3N84A 2KK6A 1O4GA 2MRKA 2AOBA 3HHMB 2Y1NA 4FBNA 2CIAA 4OHEA 2LNXA 3S8OA 2CS0A 2CRHA 2GE9A 1XA6A 2MK2A 3IMDA 1LUIA 1LCJA 3VS5A 1RJAA 2ETZA 1A1AA 4ROJA 2B3OA 1BLJA 1O4QA 5EEQA 1O42A 1KC2A 1Y1UA 3BUOB 1FU6A 3VRQA 5HKWA 1KA7A 3VROA 1NRVA 3TKZA 4WWQA 1AYDA 1LCKA 3KFJA 1O4EA 2LNWA 3GXXA 1OO3A 2CI8A 4L1BB 4DGPA 1RQQC 1D4WA 2ECDA 3CBLA 2K7AB 1O49A 1LUNA 3PJPA 1JWOA 1OO4A 3PS5A 3IN8A 2RVFA 3PLFB 1R1SA 1SPRA 2MRJA 4F5AA 3EACA 3HIZB 1P13A 2DLYA 3PSJA 1HCTB 5D0JA 1PICA 1KA6A 2EO6A 4K2RA 1X27A 4E68A 2DX0A 4GL9E 5HKYA 2L4KA 2OZOA 3CD3A 2XP1A 2BBUA 1CSZA 3ZNIA 3C7IA 4OHDA 3VS7A 1BKMA 2L3TA 1SHAA 2IUGA 3N7YA 5IBMA 2YU7A 2EO3A 3T04A 1O4DA 4FL2A 2Y1MA 1O43A 5EHRA 1LUMA 1O44A 1O4LA 1WQUA 4X6SA 3K2MA 3VS1A 1JU5A 1O4MA 2MC1A 4A4CA 5DC4A 4TZIA 1BFIA 2AUGA 4H1OA 2DLZA 1OPLA 1FBZA 2HDXA 2C0TA 3BUXB 5DC0B 1A1BA 2IUHA 4NWGA 3VGOA 2EL8A 3WA4A 3VRYA 1D4TA 1SKJA 1AOTF 4E93A 5GJHA 1KSWA 4FL3A 5AXIA 4U1PA 2FO0A 1Y57A 1QCFA 2H46E 1K9AA 1CSYA 1R1PA 3OVEA 3UF4A 3PQZA 1AYAA 4LUDA 2Y3AB 4F59A 2LQWA 1O4HA 1MILA 4P9VA 1G83A
chains in the Genus database with same CATH superfamily
1CJ1A 1O4CA 2LQNA 2EYZA 1YVHA 3NHNA 2H5KA 3OB2B 1HCSB 1O4NA 1SPSA 1YVLA 5HKZA 1AYCA 4LUEA 1O46A 2FCIA 1JYQA 2HCKA 3VRPA 3IN7A 1LKKA 2YSXA 4GPLB 4EY0A 3UYOA 1FU5A 1GRIA 1TZEE 3N8MA 1OPKA 3US4A 1CWEA 3TL0A 1O47A 1RPYA 5IBSA 4F5BA 1O4OA 2VIFA 1LUKA 1O4BA 3VS3A 1O45A 2LCTA 2EYVA 2DVJA 2IUIA 4OHIA 1BM2A 2EYYA 3VRRA 3OP0A 1O48A 1QADA 4K44A 2LRAA 4XZ0A 1JYUA 4P9ZA 4JGHA 2PNBA 2C0OA 1A1CA 1R1QA 1A07A 5DC9A 3VS6A 1UURA 1M27A 2RORA 2IZVA 2RMXA 1M61A 2DCRA 3VS2A 3OV1A 1O4IA 2HDVA 3OB1B 5EELA 1AOUF 1A09A 2KNOA 2QMSA 5GJIA 1I3ZA 1BHFA 1A1EA 1MW4A 3S8NA 3VRZA 2CBLA 2EKXA 1BFJA 1QG1E 5EHPA 2L6KA 1BHHB 1FBVA 5J3XA 1LKLA 2EU0A 2KGYA 1AYBA 3PFVA 3GQIB 2MQIA 3VS0A 5DF6A 2SRCA 3VRNA 1FMKA 5CDWA 3EAZA 3BUMB 2GSBA 3BUNB 2HUWA 1A08A 1B47A 1O4RA 4EIHA 3S9KA 3GXWA 1F1WA 2OQ1A 1F2FA 1O4AA 1IS0A 1UUSA 1D1ZA 4OHLA 4U17A 5BO4A 2PTKA 3MAZA 3MXCA 4QSYA 1BKLA 1GHUA 5AULA 2RSYA 4GWFA 1CWDL 1NZLA 1A81A 5EG3B 1AB2A 1O4KA 1BMBA 2CR4A 5KAZA 3CWGA 1O4FA 4M4ZA 1SHBA 3QWXX 3M7FA 4NWFA 1BF5A 1X6CA 4JEGA 2K79B 4XZ1A 3BKBA 3VS4A 4D8KA 4JE4A 1O4PA 2CI9A 1JYRA 1FYRA 1BG1A 2DM0A 2PNAA 1Z3KA 1H9OA 2H8HA 2HMHA 2PLDA 3BUWB 4K11A 1FHSA 3CXLA 2ABLA 1SHDA 2PLEA 2C9WA 4DGXA 1IJRA 4K45A 3MXYA 3S8LA 1BHHA 3LYVA 3PSKA 1TCEA 1ZFPE 2SHPA 2EOBA 1AD5A 1X0NA 2AOAA 3QWYA 3HCKA 2JYQA 4H34A 2C0IA 1O4JA 1O41A 1BLKA 4OHHA 5I6VA 1NZVA 3IMJA 4A4BA 3N84A 2KK6A 1O4GA 2MRKA 2AOBA 3HHMB 2Y1NA 4FBNA 2CIAA 4OHEA 2LNXA 3S8OA 2CS0A 2CRHA 2GE9A 1XA6A 2MK2A 3IMDA 1LUIA 1LCJA 3VS5A 1RJAA 2ETZA 1A1AA 4ROJA 2B3OA 1BLJA 1O4QA 5EEQA 1O42A 1KC2A 1Y1UA 3BUOB 1FU6A 3VRQA 5HKWA 1KA7A 3VROA 1NRVA 3TKZA 4WWQA 1AYDA 1LCKA 3KFJA 1O4EA 2LNWA 3GXXA 1OO3A 2CI8A 4L1BB 4DGPA 1RQQC 1D4WA 2ECDA 3CBLA 2K7AB 1O49A 1LUNA 3PJPA 1JWOA 1OO4A 3PS5A 3IN8A 2RVFA 3PLFB 1R1SA 1SPRA 2MRJA 4F5AA 3EACA 3HIZB 1P13A 2DLYA 3PSJA 1HCTB 5D0JA 1PICA 1KA6A 2EO6A 4K2RA 1X27A 4E68A 2DX0A 4GL9E 5HKYA 2L4KA 2OZOA 3CD3A 2XP1A 2BBUA 1CSZA 3ZNIA 3C7IA 4OHDA 3VS7A 1BKMA 2L3TA 1SHAA 3K2TA 2IUGA 3N7YA 5IBMA 2YU7A 2EO3A 3T04A 1O4DA 4FL2A 2Y1MA 1O43A 5EHRA 1LUMA 1O44A 1O4LA 1WQUA 4X6SA 3K2MA 3VS1A 1JU5A 1O4MA 2MC1A 4A4CA 5DC4A 4TZIA 1BFIA 2AUGA 4H1OA 2DLZA 1OPLA 1FBZA 2HDXA 2C0TA 3BUXB 5DC0B 1A1BA 2IUHA 4NWGA 3VGOA 2EL8A 3WA4A 3VRYA 1D4TA 1SKJA 1AOTF 4E93A 5GJHA 1KSWA 4FL3A 5AXIA 4U1PA 2FO0A 1Y57A 1QCFA 2H46E 1K9AA 1CSYA 1R1PA 3OVEA 3UF4A 3PQZA 1AYAA 4LUDA 2Y3AB 4F59A 2LQWA 1O4HA 1MILA 4P9VA 1G83A
chains in the Genus database with same CATH topology
1CJ1A 1O4CA 2LQNA 2EYZA 1YVHA 3NHNA 2H5KA 3OB2B 1HCSB 1O4NA 1SPSA 1YVLA 5HKZA 1AYCA 4LUEA 1O46A 2FCIA 1JYQA 2HCKA 3VRPA 3IN7A 1LKKA 2YSXA 4GPLB 4EY0A 3UYOA 1FU5A 1GRIA 1TZEE 3N8MA 1OPKA 3US4A 1CWEA 3TL0A 1O47A 1RPYA 5IBSA 4F5BA 1O4OA 2VIFA 1LUKA 1O4BA 3VS3A 1O45A 2LCTA 2EYVA 2DVJA 2IUIA 4OHIA 1BM2A 2EYYA 3VRRA 3OP0A 1O48A 1QADA 4K44A 4XZ0A 1JYUA 4P9ZA 4JGHA 2PNBA 2C0OA 1A1CA 1R1QA 1A07A 5DC9A 3VS6A 1UURA 1M27A 2RORA 2IZVA 2RMXA 1M61A 2DCRA 3VS2A 3OV1A 1O4IA 2HDVA 3OB1B 5EELA 1AOUF 1A09A 2KNOA 2QMSA 5GJIA 1I3ZA 1BHFA 1A1EA 1MW4A 3S8NA 3VRZA 2CBLA 2EKXA 1BFJA 1QG1E 5EHPA 2L6KA 1BHHB 1FBVA 5J3XA 1LKLA 2EU0A 1AYBA 3PFVA 3GQIB 2MQIA 3VS0A 5DF6A 2SRCA 3VRNA 1FMKA 5CDWA 3EAZA 3BUMB 2GSBA 3BUNB 2HUWA 1A08A 1B47A 1O4RA 4EIHA 3S9KA 3GXWA 1F1WA 2OQ1A 1F2FA 1O4AA 1IS0A 1UUSA 1D1ZA 4OHLA 4U17A 5BO4A 2PTKA 3MAZA 3MXCA 4QSYA 1BKLA 1GHUA 5AULA 2RSYA 4GWFA 1CWDL 1NZLA 1A81A 5EG3B 1AB2A 1O4KA 1BMBA 2CR4A 5KAZA 3CWGA 1O4FA 4M4ZA 1SHBA 3QWXX 3M7FA 4NWFA 1BF5A 1X6CA 4JEGA 2K79B 4XZ1A 3BKBA 3VS4A 4D8KA 4JE4A 1O4PA 2CI9A 1JYRA 1FYRA 1BG1A 2DM0A 2PNAA 1Z3KA 1H9OA 2H8HA 2HMHA 2PLDA 3BUWB 4K11A 1FHSA 3CXLA 2ABLA 1SHDA 2PLEA 2C9WA 4DGXA 1IJRA 4K45A 3MXYA 3S8LA 1BHHA 3PSKA 1TCEA 1ZFPE 2SHPA 2EOBA 1AD5A 1X0NA 2AOAA 3QWYA 3HCKA 2JYQA 4H34A 2C0IA 1O4JA 1O41A 1BLKA 4OHHA 5I6VA 1NZVA 3IMJA 4A4BA 3N84A 2KK6A 1O4GA 2MRKA 2AOBA 3HHMB 2Y1NA 4FBNA 2CIAA 4OHEA 2LNXA 3S8OA 2CS0A 2CRHA 2GE9A 1XA6A 2MK2A 3IMDA 1LUIA 1LCJA 3VS5A 1RJAA 2ETZA 1A1AA 4ROJA 2B3OA 1BLJA 1O4QA 5EEQA 1O42A 1KC2A 1Y1UA 3BUOB 1FU6A 3VRQA 5HKWA 1KA7A 3VROA 1NRVA 3TKZA 4WWQA 1AYDA 1LCKA 3KFJA 1O4EA 2LNWA 3GXXA 1OO3A 2CI8A 4L1BB 4DGPA 1RQQC 1D4WA 2ECDA 3CBLA 2K7AB 1O49A 1LUNA 3PJPA 1JWOA 1OO4A 3PS5A 3IN8A 2RVFA 3PLFB 1R1SA 1SPRA 2MRJA 4F5AA 3EACA 3HIZB 1P13A 2DLYA 3PSJA 1HCTB 5D0JA 1PICA 1KA6A 2EO6A 4K2RA 1X27A 4E68A 2DX0A 4GL9E 5HKYA 2L4KA 2OZOA 3CD3A 2XP1A 2BBUA 1CSZA 3ZNIA 3C7IA 4OHDA 3VS7A 1BKMA 2L3TA 1SHAA 2IUGA 3N7YA 5IBMA 2YU7A 2EO3A 3T04A 1O4DA 4FL2A 2Y1MA 1O43A 5EHRA 1LUMA 1O44A 1O4LA 1WQUA 4X6SA 3K2MA 3VS1A 1JU5A 1O4MA 2MC1A 4A4CA 5DC4A 4TZIA 1BFIA 2AUGA 4H1OA 2DLZA 1OPLA 1FBZA 2HDXA 2C0TA 3BUXB 5DC0B 1A1BA 2IUHA 4NWGA 3VGOA 2EL8A 3WA4A 3VRYA 1D4TA 1SKJA 1AOTF 4E93A 5GJHA 1KSWA 4FL3A 5AXIA 4U1PA 2FO0A 1Y57A 1QCFA 2H46E 1K9AA 1CSYA 1R1PA 3OVEA 3UF4A 3PQZA 1AYAA 4LUDA 2Y3AB 4F59A 2LQWA 1O4HA 1MILA 4P9VA 1G83A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CJ1 A;  1O4C A;  2LQN A;  2EYZ A;  1YVH A;  3NHN A;  2H5K A;  3OB2 B;  1HCS B;  1O4N A;  1SPS A;  1YVL A;  5HKZ A;  1AYC A;  4LUE A;  1O46 A;  2FCI A;  1JYQ A;  2HCK A;  3VRP A;  3IN7 A;  1LKK A;  2YSX A;  4GPL B;  4EY0 A;  3UYO A;  1FU5 A;  1GRI A;  1TZE E;  3N8M A;  1OPK A;  3US4 A;  1CWE A;  3TL0 A;  1O47 A;  1RPY A;  5IBS A;  4F5B A;  1O4O A;  2VIF A;  1LUK A;  1O4B A;  3VS3 A;  1O45 A;  2LCT A;  2EYV A;  2DVJ A;  2IUI A;  4OHI A;  1BM2 A;  2EYY A;  3VRR A;  3OP0 A;  1O48 A;  1QAD A;  4K44 A;  4XZ0 A;  1JYU A;  4P9Z A;  4JGH A;  2PNB A;  2C0O A;  1A1C A;  1R1Q A;  1A07 A;  5DC9 A;  3VS6 A;  1UUR A;  1M27 A;  2ROR A;  2IZV A;  2RMX A;  1M61 A;  2DCR A;  3VS2 A;  3OV1 A;  1O4I A;  2HDV A;  3OB1 B;  5EEL A;  1AOU F;  1A09 A;  2KNO A;  2QMS A;  5GJI A;  1I3Z A;  1BHF A;  1A1E A;  1MW4 A;  3S8N A;  3VRZ A;  2CBL A;  2EKX A;  1BFJ A;  1QG1 E;  5EHP A;  2L6K A;  1BHH B;  1FBV A;  5J3X A;  1LKL A;  2EU0 A;  1AYB A;  3PFV A;  3GQI B;  2MQI A;  3VS0 A;  5DF6 A;  2SRC A;  3VRN A;  1FMK A;  5CDW A;  3EAZ A;  3BUM B;  2GSB A;  3BUN B;  2HUW A;  1A08 A;  1B47 A;  1O4R A;  4EIH A;  3S9K A;  3GXW A;  1F1W A;  2OQ1 A;  1F2F A;  1O4A A;  1IS0 A;  1UUS A;  1D1Z A;  4OHL A;  4U17 A;  5BO4 A;  2PTK A;  3MAZ A;  3MXC A;  4QSY A;  1BKL A;  1GHU A;  5AUL A;  2RSY A;  4GWF A;  1CWD L;  1NZL A;  1A81 A;  5EG3 B;  1AB2 A;  1O4K A;  1BMB A;  2CR4 A;  5KAZ A;  3CWG A;  1O4F A;  4M4Z A;  1SHB A;  3QWX X;  3M7F A;  4NWF A;  1BF5 A;  1X6C A;  4JEG A;  2K79 B;  4XZ1 A;  3BKB A;  3VS4 A;  4D8K A;  4JE4 A;  1O4P A;  2CI9 A;  1JYR A;  1FYR A;  1BG1 A;  2DM0 A;  2PNA A;  1Z3K A;  1H9O A;  2H8H A;  2HMH A;  2PLD A;  3BUW B;  4K11 A;  1FHS A;  3CXL A;  2ABL A;  1SHD A;  2PLE A;  2C9W A;  4DGX A;  1IJR A;  4K45 A;  3MXY A;  3S8L A;  1BHH A;  3PSK A;  1TCE A;  1ZFP E;  2SHP A;  2EOB A;  1AD5 A;  1X0N A;  2AOA A;  3QWY A;  3HCK A;  2JYQ A;  4H34 A;  2C0I A;  1O4J A;  1O41 A;  1BLK A;  4OHH A;  5I6V A;  1NZV A;  3IMJ A;  4A4B A;  3N84 A;  2KK6 A;  1O4G A;  2MRK A;  2AOB A;  3HHM B;  2Y1N A;  4FBN A;  2CIA A;  4OHE A;  2LNX A;  3S8O A;  2CS0 A;  2CRH A;  2GE9 A;  1XA6 A;  2MK2 A;  3IMD A;  1LUI A;  1LCJ A;  3VS5 A;  1RJA A;  2ETZ A;  1A1A A;  4ROJ A;  2B3O A;  1BLJ A;  1O4Q A;  5EEQ A;  1O42 A;  1KC2 A;  1Y1U A;  3BUO B;  1FU6 A;  3VRQ A;  5HKW A;  1KA7 A;  3VRO A;  1NRV A;  3TKZ A;  4WWQ A;  1AYD A;  1LCK A;  3KFJ A;  1O4E A;  2LNW A;  3GXX A;  1OO3 A;  2CI8 A;  4L1B B;  4DGP A;  1RQQ C;  1D4W A;  2ECD A;  3CBL A;  2K7A B;  1O49 A;  1LUN A;  3PJP A;  1JWO A;  1OO4 A;  3PS5 A;  3IN8 A;  2RVF A;  3PLF B;  1R1S A;  1SPR A;  2MRJ A;  4F5A A;  3EAC A;  3HIZ B;  1P13 A;  2DLY A;  3PSJ A;  1HCT B;  5D0J A;  1PIC A;  1KA6 A;  2EO6 A;  4K2R A;  1X27 A;  4E68 A;  2DX0 A;  4GL9 E;  5HKY A;  2L4K A;  2OZO A;  3CD3 A;  2XP1 A;  2BBU A;  1CSZ A;  3ZNI A;  3C7I A;  4OHD A;  3VS7 A;  1BKM A;  2L3T A;  1SHA A;  2IUG A;  3N7Y A;  5IBM A;  2YU7 A;  2EO3 A;  3T04 A;  1O4D A;  4FL2 A;  2Y1M A;  1O43 A;  5EHR A;  1LUM A;  1O44 A;  1O4L A;  1WQU A;  4X6S A;  3K2M A;  3VS1 A;  1JU5 A;  1O4M A;  2MC1 A;  4A4C A;  5DC4 A;  4TZI A;  1BFI A;  2AUG A;  4H1O A;  2DLZ A;  1OPL A;  1FBZ A;  2HDX A;  2C0T A;  3BUX B;  5DC0 B;  1A1B A;  2IUH A;  4NWG A;  3VGO A;  2EL8 A;  3WA4 A;  3VRY A;  1D4T A;  1SKJ A;  1AOT F;  4E93 A;  5GJH A;  1KSW A;  4FL3 A;  5AXI A;  4U1P A;  2FO0 A;  1Y57 A;  1QCF A;  2H46 E;  1K9A A;  1CSY A;  1R1P A;  3OVE A;  3UF4 A;  3PQZ A;  1AYA A;  4LUD A;  2Y3A B;  4F59 A;  2LQW A;  1O4H A;  1MIL A;  4P9V A;  1G83 A; 
#chains in the Genus database with same CATH topology
 1CJ1 A;  1O4C A;  2LQN A;  2EYZ A;  1YVH A;  3NHN A;  2H5K A;  3OB2 B;  1HCS B;  1O4N A;  1SPS A;  1YVL A;  5HKZ A;  1AYC A;  4LUE A;  1O46 A;  2FCI A;  1JYQ A;  2HCK A;  3VRP A;  3IN7 A;  1LKK A;  2YSX A;  4GPL B;  4EY0 A;  3UYO A;  1FU5 A;  1GRI A;  1TZE E;  3N8M A;  1OPK A;  3US4 A;  1CWE A;  3TL0 A;  1O47 A;  1RPY A;  5IBS A;  4F5B A;  1O4O A;  2VIF A;  1LUK A;  1O4B A;  3VS3 A;  1O45 A;  2LCT A;  2EYV A;  2DVJ A;  2IUI A;  4OHI A;  1BM2 A;  2EYY A;  3VRR A;  3OP0 A;  1O48 A;  1QAD A;  4K44 A;  2LRA A;  4XZ0 A;  1JYU A;  4P9Z A;  4JGH A;  2PNB A;  2C0O A;  1A1C A;  1R1Q A;  1A07 A;  5DC9 A;  3VS6 A;  1UUR A;  1M27 A;  2ROR A;  2IZV A;  2RMX A;  1M61 A;  2DCR A;  3VS2 A;  3OV1 A;  1O4I A;  2HDV A;  3OB1 B;  5EEL A;  1AOU F;  1A09 A;  2KNO A;  2QMS A;  5GJI A;  1I3Z A;  1BHF A;  1A1E A;  1MW4 A;  3S8N A;  3VRZ A;  2CBL A;  2EKX A;  1BFJ A;  1QG1 E;  5EHP A;  2L6K A;  1BHH B;  1FBV A;  5J3X A;  1LKL A;  2EU0 A;  2KGY A;  1AYB A;  3PFV A;  3GQI B;  2MQI A;  3VS0 A;  5DF6 A;  2SRC A;  3VRN A;  1FMK A;  5CDW A;  3EAZ A;  3BUM B;  2GSB A;  3BUN B;  2HUW A;  1A08 A;  1B47 A;  1O4R A;  4EIH A;  3S9K A;  3GXW A;  1F1W A;  2OQ1 A;  1F2F A;  1O4A A;  1IS0 A;  1UUS A;  1D1Z A;  4OHL A;  4U17 A;  5BO4 A;  2PTK A;  3MAZ A;  3MXC A;  4QSY A;  1BKL A;  1GHU A;  5AUL A;  2RSY A;  4GWF A;  1CWD L;  1NZL A;  1A81 A;  5EG3 B;  1AB2 A;  1O4K A;  1BMB A;  2CR4 A;  5KAZ A;  3CWG A;  1O4F A;  4M4Z A;  1SHB A;  3QWX X;  3M7F A;  4NWF A;  1BF5 A;  1X6C A;  4JEG A;  2K79 B;  4XZ1 A;  3BKB A;  3VS4 A;  4D8K A;  4JE4 A;  1O4P A;  2CI9 A;  1JYR A;  1FYR A;  1BG1 A;  2DM0 A;  2PNA A;  1Z3K A;  1H9O A;  2H8H A;  2HMH A;  2PLD A;  3BUW B;  4K11 A;  1FHS A;  3CXL A;  2ABL A;  1SHD A;  2PLE A;  2C9W A;  4DGX A;  1IJR A;  4K45 A;  3MXY A;  3S8L A;  1BHH A;  3LYV A;  3PSK A;  1TCE A;  1ZFP E;  2SHP A;  2EOB A;  1AD5 A;  1X0N A;  2AOA A;  3QWY A;  3HCK A;  2JYQ A;  4H34 A;  2C0I A;  1O4J A;  1O41 A;  1BLK A;  4OHH A;  5I6V A;  1NZV A;  3IMJ A;  4A4B A;  3N84 A;  2KK6 A;  1O4G A;  2MRK A;  2AOB A;  3HHM B;  2Y1N A;  4FBN A;  2CIA A;  4OHE A;  2LNX A;  3S8O A;  2CS0 A;  2CRH A;  2GE9 A;  1XA6 A;  2MK2 A;  3IMD A;  1LUI A;  1LCJ A;  3VS5 A;  1RJA A;  2ETZ A;  1A1A A;  4ROJ A;  2B3O A;  1BLJ A;  1O4Q A;  5EEQ A;  1O42 A;  1KC2 A;  1Y1U A;  3BUO B;  1FU6 A;  3VRQ A;  5HKW A;  1KA7 A;  3VRO A;  1NRV A;  3TKZ A;  4WWQ A;  1AYD A;  1LCK A;  3KFJ A;  1O4E A;  2LNW A;  3GXX A;  1OO3 A;  2CI8 A;  4L1B B;  4DGP A;  1RQQ C;  1D4W A;  2ECD A;  3CBL A;  2K7A B;  1O49 A;  1LUN A;  3PJP A;  1JWO A;  1OO4 A;  3PS5 A;  3IN8 A;  2RVF A;  3PLF B;  1R1S A;  1SPR A;  2MRJ A;  4F5A A;  3EAC A;  3HIZ B;  1P13 A;  2DLY A;  3PSJ A;  1HCT B;  5D0J A;  1PIC A;  1KA6 A;  2EO6 A;  4K2R A;  1X27 A;  4E68 A;  2DX0 A;  4GL9 E;  5HKY A;  2L4K A;  2OZO A;  3CD3 A;  2XP1 A;  2BBU A;  1CSZ A;  3ZNI A;  3C7I A;  4OHD A;  3VS7 A;  1BKM A;  2L3T A;  1SHA A;  3K2T A;  2IUG A;  3N7Y A;  5IBM A;  2YU7 A;  2EO3 A;  3T04 A;  1O4D A;  4FL2 A;  2Y1M A;  1O43 A;  5EHR A;  1LUM A;  1O44 A;  1O4L A;  1WQU A;  4X6S A;  3K2M A;  3VS1 A;  1JU5 A;  1O4M A;  2MC1 A;  4A4C A;  5DC4 A;  4TZI A;  1BFI A;  2AUG A;  4H1O A;  2DLZ A;  1OPL A;  1FBZ A;  2HDX A;  2C0T A;  3BUX B;  5DC0 B;  1A1B A;  2IUH A;  4NWG A;  3VGO A;  2EL8 A;  3WA4 A;  3VRY A;  1D4T A;  1SKJ A;  1AOT F;  4E93 A;  5GJH A;  1KSW A;  4FL3 A;  5AXI A;  4U1P A;  2FO0 A;  1Y57 A;  1QCF A;  2H46 E;  1K9A A;  1CSY A;  1R1P A;  3OVE A;  3UF4 A;  3PQZ A;  1AYA A;  4LUD A;  2Y3A B;  4F59 A;  2LQW A;  1O4H A;  1MIL A;  4P9V A;  1G83 A; 
#chains in the Genus database with same CATH homology
 1CJ1 A;  1O4C A;  2LQN A;  2EYZ A;  1YVH A;  3NHN A;  2H5K A;  3OB2 B;  1HCS B;  1O4N A;  1SPS A;  1YVL A;  5HKZ A;  1AYC A;  4LUE A;  1O46 A;  2FCI A;  1JYQ A;  2HCK A;  3VRP A;  3IN7 A;  1LKK A;  2YSX A;  4GPL B;  4EY0 A;  3UYO A;  1FU5 A;  1GRI A;  1TZE E;  3N8M A;  1OPK A;  3US4 A;  1CWE A;  3TL0 A;  1O47 A;  1RPY A;  5IBS A;  4F5B A;  1O4O A;  2VIF A;  1LUK A;  1O4B A;  3VS3 A;  1O45 A;  2LCT A;  2EYV A;  2DVJ A;  2IUI A;  4OHI A;  1BM2 A;  2EYY A;  3VRR A;  3OP0 A;  1O48 A;  1QAD A;  4K44 A;  4XZ0 A;  1JYU A;  4P9Z A;  4JGH A;  2PNB A;  2C0O A;  1A1C A;  1R1Q A;  1A07 A;  5DC9 A;  3VS6 A;  1UUR A;  1M27 A;  2ROR A;  2IZV A;  2RMX A;  1M61 A;  2DCR A;  3VS2 A;  3OV1 A;  1O4I A;  2HDV A;  3OB1 B;  5EEL A;  1AOU F;  1A09 A;  2KNO A;  2QMS A;  5GJI A;  1I3Z A;  1BHF A;  1A1E A;  1MW4 A;  3S8N A;  3VRZ A;  2CBL A;  2EKX A;  1BFJ A;  1QG1 E;  5EHP A;  2L6K A;  1BHH B;  1FBV A;  5J3X A;  1LKL A;  2EU0 A;  1AYB A;  3PFV A;  3GQI B;  2MQI A;  3VS0 A;  5DF6 A;  2SRC A;  3VRN A;  1FMK A;  5CDW A;  3EAZ A;  3BUM B;  2GSB A;  3BUN B;  2HUW A;  1A08 A;  1B47 A;  1O4R A;  4EIH A;  3S9K A;  3GXW A;  1F1W A;  2OQ1 A;  1F2F A;  1O4A A;  1IS0 A;  1UUS A;  1D1Z A;  4OHL A;  4U17 A;  5BO4 A;  2PTK A;  3MAZ A;  3MXC A;  4QSY A;  1BKL A;  1GHU A;  5AUL A;  2RSY A;  4GWF A;  1CWD L;  1NZL A;  1A81 A;  5EG3 B;  1AB2 A;  1O4K A;  1BMB A;  2CR4 A;  5KAZ A;  3CWG A;  1O4F A;  4M4Z A;  1SHB A;  3QWX X;  3M7F A;  4NWF A;  1BF5 A;  1X6C A;  4JEG A;  2K79 B;  4XZ1 A;  3BKB A;  3VS4 A;  4D8K A;  4JE4 A;  1O4P A;  2CI9 A;  1JYR A;  1FYR A;  1BG1 A;  2DM0 A;  2PNA A;  1Z3K A;  1H9O A;  2H8H A;  2HMH A;  2PLD A;  3BUW B;  4K11 A;  1FHS A;  3CXL A;  2ABL A;  1SHD A;  2PLE A;  2C9W A;  4DGX A;  1IJR A;  4K45 A;  3MXY A;  3S8L A;  1BHH A;  3PSK A;  1TCE A;  1ZFP E;  2SHP A;  2EOB A;  1AD5 A;  1X0N A;  2AOA A;  3QWY A;  3HCK A;  2JYQ A;  4H34 A;  2C0I A;  1O4J A;  1O41 A;  1BLK A;  4OHH A;  5I6V A;  1NZV A;  3IMJ A;  4A4B A;  3N84 A;  2KK6 A;  1O4G A;  2MRK A;  2AOB A;  3HHM B;  2Y1N A;  4FBN A;  2CIA A;  4OHE A;  2LNX A;  3S8O A;  2CS0 A;  2CRH A;  2GE9 A;  1XA6 A;  2MK2 A;  3IMD A;  1LUI A;  1LCJ A;  3VS5 A;  1RJA A;  2ETZ A;  1A1A A;  4ROJ A;  2B3O A;  1BLJ A;  1O4Q A;  5EEQ A;  1O42 A;  1KC2 A;  1Y1U A;  3BUO B;  1FU6 A;  3VRQ A;  5HKW A;  1KA7 A;  3VRO A;  1NRV A;  3TKZ A;  4WWQ A;  1AYD A;  1LCK A;  3KFJ A;  1O4E A;  2LNW A;  3GXX A;  1OO3 A;  2CI8 A;  4L1B B;  4DGP A;  1RQQ C;  1D4W A;  2ECD A;  3CBL A;  2K7A B;  1O49 A;  1LUN A;  3PJP A;  1JWO A;  1OO4 A;  3PS5 A;  3IN8 A;  2RVF A;  3PLF B;  1R1S A;  1SPR A;  2MRJ A;  4F5A A;  3EAC A;  3HIZ B;  1P13 A;  2DLY A;  3PSJ A;  1HCT B;  5D0J A;  1PIC A;  1KA6 A;  2EO6 A;  4K2R A;  1X27 A;  4E68 A;  2DX0 A;  4GL9 E;  5HKY A;  2L4K A;  2OZO A;  3CD3 A;  2XP1 A;  2BBU A;  1CSZ A;  3ZNI A;  3C7I A;  4OHD A;  3VS7 A;  1BKM A;  2L3T A;  1SHA A;  2IUG A;  3N7Y A;  5IBM A;  2YU7 A;  2EO3 A;  3T04 A;  1O4D A;  4FL2 A;  2Y1M A;  1O43 A;  5EHR A;  1LUM A;  1O44 A;  1O4L A;  1WQU A;  4X6S A;  3K2M A;  3VS1 A;  1JU5 A;  1O4M A;  2MC1 A;  4A4C A;  5DC4 A;  4TZI A;  1BFI A;  2AUG A;  4H1O A;  2DLZ A;  1OPL A;  1FBZ A;  2HDX A;  2C0T A;  3BUX B;  5DC0 B;  1A1B A;  2IUH A;  4NWG A;  3VGO A;  2EL8 A;  3WA4 A;  3VRY A;  1D4T A;  1SKJ A;  1AOT F;  4E93 A;  5GJH A;  1KSW A;  4FL3 A;  5AXI A;  4U1P A;  2FO0 A;  1Y57 A;  1QCF A;  2H46 E;  1K9A A;  1CSY A;  1R1P A;  3OVE A;  3UF4 A;  3PQZ A;  1AYA A;  4LUD A;  2Y3A B;  4F59 A;  2LQW A;  1O4H A;  1MIL A;  4P9V A;  1G83 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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