3S8NA

Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
101
structure length
101
Chain Sequence
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
pubmed doi rcsb
molecule tags Signaling protein/antagonist
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 23
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2011-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3s8nA00
4OHDA 1O4MA 2MRJA 4F5AA 1O42A 2OQ1A 2C0OA 1JWOA 3BUXB 2IUGA 3EAZA 3BUWB 4LUDA 3VRPA 2KK6A 2CIAA 3UYOA 2AOAA 1D4WA 1KSWA 1BLJA 1O4CA 4H34A 3MAZA 2ABLA 1O43A 2LNWA 3VROA 2L6KA 1O4GA 4K45A 1ZFPE 2LNXA 4JGHA 2L3TA 2RMXA 3KFJA 2ETZA 4QSYA 2EYVA 2L4KA 2DVJA 2OZOA 3VS7A 3K2MA 4X6SA 2YSXA 4K44A 1AD5A 1D4TA 4ROJA 3GXWA 1FBVA 1BKMA 3OV1A 4JEGA 1A1BA 2CBLA 3PQZA 3S9KA 4K11A 4F5BA 2AUGA 1BM2A 1R1QA 5IBSA 2IZVA 3UF4A 3PFVA 1CSYA 3PLFB 1JU5A 1H9OA 1QCFA 3EACA 2MC1A 1BLKA 2SHPA 1UUSA 4GWFA 1QADA 4JE4A 1R1PA 5AXIA 1K9AA 2MRKA 4OHEA 4WWQA 1YVLA 5AULA 3VGOA 5IBMA 1GHUA 1O4IA 3IN8A 2BBUA 1OPKA 4XZ1A 3VRQA 4L1BB 4A4BA 5EG3B 3CXLA 1A09A 1QG1E 2HCKA 3CBLA 1MW4A 1A1AA 3CD3A 1NRVA 2DX0A 2H46E 3OP0A 3OB2B 5HKWA 2PLDA 3PSJA 4FBNA 1SPSA 1R1SA 3S8NA 1O47A 2XP1A 3IMJA 4XZ0A 1SHBA 4FL3A 3VS2A 3US4A 1LUMA 1Y57A 3ZNIA 1SKJA 1O41A 3PS5A 2KNOA 2SRCA 1JYQA 2VIFA 1HCTB 3HCKA 1I3ZA 1Y1UA 2H5KA 1P13A 2CR4A 2LQNA 1TZEE 1O48A 3OB1B 1KA6A 1A1EA 1FMKA 4DGPA 1O4RA 4TZIA 2HDXA 2EO6A 2DLYA 2FO0A 3VS5A 4E68A 1BFJA 2LCTA 1X0NA 2EU0A 1AB2A 1JYUA 1RPYA 4NWFA 4FL2A 3VRNA 4OHLA 3BUOB 3BUNB 5BO4A 3N84A 3N7YA 1OO4A 1O49A 2DCRA 5EEQA 1UURA 1FHSA 2EO3A 3VRRA 3BUMB 3CWGA 1O4KA 2PNAA 1SHDA 1AOTF 3PSKA 2EKXA 1BG1A 2CI8A 4EY0A 2C0IA 2CI9A 1KC2A 5EHRA 1O4HA 1BMBA 3MXCA 1F1WA 1AYDA 1A08A 1IS0A 1BFIA 2PNBA 2GE9A 2RORA 1WQUA 1LCJA 3TL0A 1CJ1A 2MK2A 2RVFA 1FU5A 2JYQA 1O46A 3IN7A 2ECDA 1A1CA 4U17A 3QWYA 1BHFA 1MILA 1X6CA 1AYAA 5D0JA 1GRIA 2AOBA 1O4BA 3VS4A 2QMSA 1A07A 1NZLA 1LUNA 1LUKA 3NHNA 1LUIA 2Y1NA 5HKZA 2DM0A 3C7IA 3HHMB 1BHHA 2EYZA 2HDVA 3OVEA 3T04A 3VS3A 1NZVA 1CWEA 4GPLB 1YVHA 1O4AA 1O4EA 2CRHA 1FYRA 2K7AB 1CSZA 3GXXA 4D8KA 2C9WA 3IMDA 2B3OA 1A81A 1SHAA 4P9VA 1G83A 5EHPA 3S8OA 1B47A 1RQQC 3TKZA 1AOUF 2PTKA 3BKBA 5DF6A 3VS1A 3QWXX 5GJHA 1BKLA 4OHHA 2Y1MA 4OHIA 1FBZA 4H1OA 1TCEA 4F59A 1O4OA 1O4DA 4U1PA 2FCIA 3VRZA 1O44A 3PJPA 4P9ZA 1O4JA 5EELA 1IJRA 5CDWA 2IUIA 5I6VA 1OPLA 2GSBA 4GL9E 3VS0A 1KA7A 1LKLA 1HCSB 2DLZA 3M7FA 2MQIA 1LKKA 3VRYA 4A4CA 4M4ZA 2LQWA 3GQIB 1BHHB 3N8MA 1O4NA 1O4QA 2Y3AB 1X27A 3VS6A 2PLEA 1RJAA 1AYCA 1SPRA 1JYRA 4K2RA 1CWDL 1XA6A 4NWGA 1O4PA 1Z3KA 1O4FA 2RSYA 5DC9A 1OO3A 1D1ZA 1PICA 4LUEA 4DGXA 4E93A 2C0TA 5J3XA 1O4LA 2YU7A 2HMHA 1F2FA 1M61A 1AYBA 3S8LA 5KAZA 5HKYA 1O45A 1FU6A 5DC4A 3WA4A 1LCKA 5GJIA 2HUWA 2EYYA 2EOBA 1M27A 2K79B 1BF5A 2EL8A 3HIZB 4EIHA 5DC0B 2CS0A 2H8HA 2IUHA 3MXYA
chains in the Genus database with same CATH superfamily
4OHDA 1O4MA 2MRJA 4F5AA 1O42A 2OQ1A 2C0OA 1JWOA 3BUXB 2IUGA 3EAZA 3BUWB 4LUDA 3VRPA 2KK6A 2CIAA 3UYOA 2AOAA 1D4WA 1KSWA 1BLJA 1O4CA 4H34A 3MAZA 2ABLA 1O43A 2LNWA 3VROA 2L6KA 1O4GA 4K45A 1ZFPE 2LNXA 4JGHA 2L3TA 2RMXA 3KFJA 2ETZA 4QSYA 2EYVA 2L4KA 2DVJA 2OZOA 3VS7A 3K2MA 4X6SA 2YSXA 4K44A 1AD5A 1D4TA 4ROJA 3GXWA 1FBVA 1BKMA 3OV1A 4JEGA 1A1BA 2CBLA 3PQZA 3S9KA 4K11A 4F5BA 2AUGA 1BM2A 1R1QA 5IBSA 2IZVA 3UF4A 3PFVA 1CSYA 3PLFB 1JU5A 1H9OA 1QCFA 3EACA 2MC1A 1BLKA 3K2TA 2SHPA 1UUSA 4GWFA 1QADA 4JE4A 1R1PA 5AXIA 1K9AA 2MRKA 4OHEA 4WWQA 1YVLA 5AULA 3VGOA 5IBMA 1GHUA 1O4IA 3IN8A 2BBUA 1OPKA 4XZ1A 3VRQA 4L1BB 4A4BA 5EG3B 3CXLA 1A09A 1QG1E 2HCKA 3CBLA 1MW4A 1A1AA 3CD3A 1NRVA 2DX0A 2LRAA 2H46E 3OP0A 3OB2B 5HKWA 2PLDA 3PSJA 4FBNA 1SPSA 1R1SA 3S8NA 1O47A 2XP1A 3IMJA 4XZ0A 1SHBA 4FL3A 3VS2A 3US4A 1LUMA 1Y57A 3ZNIA 1SKJA 1O41A 3PS5A 2KNOA 2SRCA 1JYQA 2VIFA 1HCTB 3HCKA 1I3ZA 1Y1UA 2H5KA 1P13A 2CR4A 2LQNA 1TZEE 1O48A 3OB1B 1KA6A 1A1EA 1FMKA 4DGPA 1O4RA 4TZIA 2HDXA 2EO6A 2DLYA 2FO0A 3VS5A 4E68A 1BFJA 2LCTA 1X0NA 2EU0A 1AB2A 1JYUA 1RPYA 4NWFA 4FL2A 3VRNA 4OHLA 3BUOB 3BUNB 5BO4A 3N84A 3N7YA 1OO4A 1O49A 2DCRA 5EEQA 1UURA 1FHSA 2EO3A 3VRRA 3BUMB 3CWGA 1O4KA 2PNAA 1SHDA 1AOTF 3PSKA 2EKXA 1BG1A 2CI8A 4EY0A 2C0IA 2CI9A 1KC2A 5EHRA 1O4HA 1BMBA 3MXCA 1F1WA 1AYDA 1A08A 1IS0A 1BFIA 2PNBA 2GE9A 2RORA 1WQUA 1LCJA 3TL0A 1CJ1A 2MK2A 2RVFA 1FU5A 2JYQA 1O46A 3IN7A 2ECDA 1A1CA 4U17A 3QWYA 1BHFA 1MILA 1X6CA 1AYAA 5D0JA 1GRIA 2AOBA 1O4BA 3VS4A 2QMSA 1A07A 1NZLA 1LUNA 1LUKA 3NHNA 1LUIA 2Y1NA 5HKZA 2DM0A 3C7IA 3HHMB 1BHHA 2EYZA 2HDVA 3OVEA 3T04A 3VS3A 1NZVA 1CWEA 4GPLB 1YVHA 1O4AA 1O4EA 2CRHA 1FYRA 2K7AB 1CSZA 3GXXA 4D8KA 2C9WA 3IMDA 2B3OA 1A81A 1SHAA 4P9VA 1G83A 5EHPA 3S8OA 1B47A 1RQQC 3TKZA 1AOUF 2PTKA 3BKBA 5DF6A 3VS1A 3QWXX 5GJHA 1BKLA 4OHHA 2Y1MA 4OHIA 1FBZA 4H1OA 1TCEA 4F59A 1O4OA 1O4DA 4U1PA 2FCIA 3VRZA 1O44A 3PJPA 4P9ZA 1O4JA 5EELA 1IJRA 5CDWA 2IUIA 5I6VA 1OPLA 2GSBA 4GL9E 3VS0A 1KA7A 1LKLA 1HCSB 2DLZA 3M7FA 2MQIA 1LKKA 3VRYA 4A4CA 4M4ZA 2LQWA 3GQIB 1BHHB 3N8MA 1O4NA 1O4QA 2Y3AB 1X27A 3VS6A 2PLEA 1RJAA 2KGYA 1AYCA 1SPRA 1JYRA 4K2RA 1CWDL 1XA6A 4NWGA 1O4PA 1Z3KA 1O4FA 2RSYA 5DC9A 1OO3A 1D1ZA 1PICA 4LUEA 4DGXA 4E93A 2C0TA 5J3XA 1O4LA 2YU7A 2HMHA 1F2FA 1M61A 1AYBA 3S8LA 3LYVA 5KAZA 5HKYA 1O45A 1FU6A 5DC4A 3WA4A 1LCKA 5GJIA 2HUWA 2EYYA 2EOBA 1M27A 2K79B 1BF5A 2EL8A 3HIZB 4EIHA 5DC0B 2CS0A 2H8HA 2IUHA 3MXYA
chains in the Genus database with same CATH topology
4OHDA 1O4MA 2MRJA 4F5AA 1O42A 2OQ1A 2C0OA 1JWOA 3BUXB 2IUGA 3EAZA 3BUWB 4LUDA 3VRPA 2KK6A 2CIAA 3UYOA 2AOAA 1D4WA 1KSWA 1BLJA 1O4CA 4H34A 3MAZA 2ABLA 1O43A 2LNWA 3VROA 2L6KA 1O4GA 4K45A 1ZFPE 2LNXA 4JGHA 2L3TA 2RMXA 3KFJA 2ETZA 4QSYA 2EYVA 2L4KA 2DVJA 2OZOA 3VS7A 3K2MA 4X6SA 2YSXA 4K44A 1AD5A 1D4TA 4ROJA 3GXWA 1FBVA 1BKMA 3OV1A 4JEGA 1A1BA 2CBLA 3PQZA 3S9KA 4K11A 4F5BA 2AUGA 1BM2A 1R1QA 5IBSA 2IZVA 3UF4A 3PFVA 1CSYA 3PLFB 1JU5A 1H9OA 1QCFA 3EACA 2MC1A 1BLKA 2SHPA 1UUSA 4GWFA 1QADA 4JE4A 1R1PA 5AXIA 1K9AA 2MRKA 4OHEA 4WWQA 1YVLA 5AULA 3VGOA 5IBMA 1GHUA 1O4IA 3IN8A 2BBUA 1OPKA 4XZ1A 3VRQA 4L1BB 4A4BA 5EG3B 3CXLA 1A09A 1QG1E 2HCKA 3CBLA 1MW4A 1A1AA 3CD3A 1NRVA 2DX0A 2H46E 3OP0A 3OB2B 5HKWA 2PLDA 3PSJA 4FBNA 1SPSA 1R1SA 3S8NA 1O47A 2XP1A 3IMJA 4XZ0A 1SHBA 4FL3A 3VS2A 3US4A 1LUMA 1Y57A 3ZNIA 1SKJA 1O41A 3PS5A 2KNOA 2SRCA 1JYQA 2VIFA 1HCTB 3HCKA 1I3ZA 1Y1UA 2H5KA 1P13A 2CR4A 2LQNA 1TZEE 1O48A 3OB1B 1KA6A 1A1EA 1FMKA 4DGPA 1O4RA 4TZIA 2HDXA 2EO6A 2DLYA 2FO0A 3VS5A 4E68A 1BFJA 2LCTA 1X0NA 2EU0A 1AB2A 1JYUA 1RPYA 4NWFA 4FL2A 3VRNA 4OHLA 3BUOB 3BUNB 5BO4A 3N84A 3N7YA 1OO4A 1O49A 2DCRA 5EEQA 1UURA 1FHSA 2EO3A 3VRRA 3BUMB 3CWGA 1O4KA 2PNAA 1SHDA 1AOTF 3PSKA 2EKXA 1BG1A 2CI8A 4EY0A 2C0IA 2CI9A 1KC2A 5EHRA 1O4HA 1BMBA 3MXCA 1F1WA 1AYDA 1A08A 1IS0A 1BFIA 2PNBA 2GE9A 2RORA 1WQUA 1LCJA 3TL0A 1CJ1A 2MK2A 2RVFA 1FU5A 2JYQA 1O46A 3IN7A 2ECDA 1A1CA 4U17A 3QWYA 1BHFA 1MILA 1X6CA 1AYAA 5D0JA 1GRIA 2AOBA 1O4BA 3VS4A 2QMSA 1A07A 1NZLA 1LUNA 1LUKA 3NHNA 1LUIA 2Y1NA 5HKZA 2DM0A 3C7IA 3HHMB 1BHHA 2EYZA 2HDVA 3OVEA 3T04A 3VS3A 1NZVA 1CWEA 4GPLB 1YVHA 1O4AA 1O4EA 2CRHA 1FYRA 2K7AB 1CSZA 3GXXA 4D8KA 2C9WA 3IMDA 2B3OA 1A81A 1SHAA 4P9VA 1G83A 5EHPA 3S8OA 1B47A 1RQQC 3TKZA 1AOUF 2PTKA 3BKBA 5DF6A 3VS1A 3QWXX 5GJHA 1BKLA 4OHHA 2Y1MA 4OHIA 1FBZA 4H1OA 1TCEA 4F59A 1O4OA 1O4DA 4U1PA 2FCIA 3VRZA 1O44A 3PJPA 4P9ZA 1O4JA 5EELA 1IJRA 5CDWA 2IUIA 5I6VA 1OPLA 2GSBA 4GL9E 3VS0A 1KA7A 1LKLA 1HCSB 2DLZA 3M7FA 2MQIA 1LKKA 3VRYA 4A4CA 4M4ZA 2LQWA 3GQIB 1BHHB 3N8MA 1O4NA 1O4QA 2Y3AB 1X27A 3VS6A 2PLEA 1RJAA 1AYCA 1SPRA 1JYRA 4K2RA 1CWDL 1XA6A 4NWGA 1O4PA 1Z3KA 1O4FA 2RSYA 5DC9A 1OO3A 1D1ZA 1PICA 4LUEA 4DGXA 4E93A 2C0TA 5J3XA 1O4LA 2YU7A 2HMHA 1F2FA 1M61A 1AYBA 3S8LA 5KAZA 5HKYA 1O45A 1FU6A 5DC4A 3WA4A 1LCKA 5GJIA 2HUWA 2EYYA 2EOBA 1M27A 2K79B 1BF5A 2EL8A 3HIZB 4EIHA 5DC0B 2CS0A 2H8HA 2IUHA 3MXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OHD A;  1O4M A;  2MRJ A;  4F5A A;  1O42 A;  2OQ1 A;  2C0O A;  1JWO A;  3BUX B;  2IUG A;  3EAZ A;  3BUW B;  4LUD A;  3VRP A;  2KK6 A;  2CIA A;  3UYO A;  2AOA A;  1D4W A;  1KSW A;  1BLJ A;  1O4C A;  4H34 A;  3MAZ A;  2ABL A;  1O43 A;  2LNW A;  3VRO A;  2L6K A;  1O4G A;  4K45 A;  1ZFP E;  2LNX A;  4JGH A;  2L3T A;  2RMX A;  3KFJ A;  2ETZ A;  4QSY A;  2EYV A;  2L4K A;  2DVJ A;  2OZO A;  3VS7 A;  3K2M A;  4X6S A;  2YSX A;  4K44 A;  1AD5 A;  1D4T A;  4ROJ A;  3GXW A;  1FBV A;  1BKM A;  3OV1 A;  4JEG A;  1A1B A;  2CBL A;  3PQZ A;  3S9K A;  4K11 A;  4F5B A;  2AUG A;  1BM2 A;  1R1Q A;  5IBS A;  2IZV A;  3UF4 A;  3PFV A;  1CSY A;  3PLF B;  1JU5 A;  1H9O A;  1QCF A;  3EAC A;  2MC1 A;  1BLK A;  2SHP A;  1UUS A;  4GWF A;  1QAD A;  4JE4 A;  1R1P A;  5AXI A;  1K9A A;  2MRK A;  4OHE A;  4WWQ A;  1YVL A;  5AUL A;  3VGO A;  5IBM A;  1GHU A;  1O4I A;  3IN8 A;  2BBU A;  1OPK A;  4XZ1 A;  3VRQ A;  4L1B B;  4A4B A;  5EG3 B;  3CXL A;  1A09 A;  1QG1 E;  2HCK A;  3CBL A;  1MW4 A;  1A1A A;  3CD3 A;  1NRV A;  2DX0 A;  2H46 E;  3OP0 A;  3OB2 B;  5HKW A;  2PLD A;  3PSJ A;  4FBN A;  1SPS A;  1R1S A;  3S8N A;  1O47 A;  2XP1 A;  3IMJ A;  4XZ0 A;  1SHB A;  4FL3 A;  3VS2 A;  3US4 A;  1LUM A;  1Y57 A;  3ZNI A;  1SKJ A;  1O41 A;  3PS5 A;  2KNO A;  2SRC A;  1JYQ A;  2VIF A;  1HCT B;  3HCK A;  1I3Z A;  1Y1U A;  2H5K A;  1P13 A;  2CR4 A;  2LQN A;  1TZE E;  1O48 A;  3OB1 B;  1KA6 A;  1A1E A;  1FMK A;  4DGP A;  1O4R A;  4TZI A;  2HDX A;  2EO6 A;  2DLY A;  2FO0 A;  3VS5 A;  4E68 A;  1BFJ A;  2LCT A;  1X0N A;  2EU0 A;  1AB2 A;  1JYU A;  1RPY A;  4NWF A;  4FL2 A;  3VRN A;  4OHL A;  3BUO B;  3BUN B;  5BO4 A;  3N84 A;  3N7Y A;  1OO4 A;  1O49 A;  2DCR A;  5EEQ A;  1UUR A;  1FHS A;  2EO3 A;  3VRR A;  3BUM B;  3CWG A;  1O4K A;  2PNA A;  1SHD A;  1AOT F;  3PSK A;  2EKX A;  1BG1 A;  2CI8 A;  4EY0 A;  2C0I A;  2CI9 A;  1KC2 A;  5EHR A;  1O4H A;  1BMB A;  3MXC A;  1F1W A;  1AYD A;  1A08 A;  1IS0 A;  1BFI A;  2PNB A;  2GE9 A;  2ROR A;  1WQU A;  1LCJ A;  3TL0 A;  1CJ1 A;  2MK2 A;  2RVF A;  1FU5 A;  2JYQ A;  1O46 A;  3IN7 A;  2ECD A;  1A1C A;  4U17 A;  3QWY A;  1BHF A;  1MIL A;  1X6C A;  1AYA A;  5D0J A;  1GRI A;  2AOB A;  1O4B A;  3VS4 A;  2QMS A;  1A07 A;  1NZL A;  1LUN A;  1LUK A;  3NHN A;  1LUI A;  2Y1N A;  5HKZ A;  2DM0 A;  3C7I A;  3HHM B;  1BHH A;  2EYZ A;  2HDV A;  3OVE A;  3T04 A;  3VS3 A;  1NZV A;  1CWE A;  4GPL B;  1YVH A;  1O4A A;  1O4E A;  2CRH A;  1FYR A;  2K7A B;  1CSZ A;  3GXX A;  4D8K A;  2C9W A;  3IMD A;  2B3O A;  1A81 A;  1SHA A;  4P9V A;  1G83 A;  5EHP A;  3S8O A;  1B47 A;  1RQQ C;  3TKZ A;  1AOU F;  2PTK A;  3BKB A;  5DF6 A;  3VS1 A;  3QWX X;  5GJH A;  1BKL A;  4OHH A;  2Y1M A;  4OHI A;  1FBZ A;  4H1O A;  1TCE A;  4F59 A;  1O4O A;  1O4D A;  4U1P A;  2FCI A;  3VRZ A;  1O44 A;  3PJP A;  4P9Z A;  1O4J A;  5EEL A;  1IJR A;  5CDW A;  2IUI A;  5I6V A;  1OPL A;  2GSB A;  4GL9 E;  3VS0 A;  1KA7 A;  1LKL A;  1HCS B;  2DLZ A;  3M7F A;  2MQI A;  1LKK A;  3VRY A;  4A4C A;  4M4Z A;  2LQW A;  3GQI B;  1BHH B;  3N8M A;  1O4N A;  1O4Q A;  2Y3A B;  1X27 A;  3VS6 A;  2PLE A;  1RJA A;  1AYC A;  1SPR A;  1JYR A;  4K2R A;  1CWD L;  1XA6 A;  4NWG A;  1O4P A;  1Z3K A;  1O4F A;  2RSY A;  5DC9 A;  1OO3 A;  1D1Z A;  1PIC A;  4LUE A;  4DGX A;  4E93 A;  2C0T A;  5J3X A;  1O4L A;  2YU7 A;  2HMH A;  1F2F A;  1M61 A;  1AYB A;  3S8L A;  5KAZ A;  5HKY A;  1O45 A;  1FU6 A;  5DC4 A;  3WA4 A;  1LCK A;  5GJI A;  2HUW A;  2EYY A;  2EOB A;  1M27 A;  2K79 B;  1BF5 A;  2EL8 A;  3HIZ B;  4EIH A;  5DC0 B;  2CS0 A;  2H8H A;  2IUH A;  3MXY A; 
#chains in the Genus database with same CATH topology
 4OHD A;  1O4M A;  2MRJ A;  4F5A A;  1O42 A;  2OQ1 A;  2C0O A;  1JWO A;  3BUX B;  2IUG A;  3EAZ A;  3BUW B;  4LUD A;  3VRP A;  2KK6 A;  2CIA A;  3UYO A;  2AOA A;  1D4W A;  1KSW A;  1BLJ A;  1O4C A;  4H34 A;  3MAZ A;  2ABL A;  1O43 A;  2LNW A;  3VRO A;  2L6K A;  1O4G A;  4K45 A;  1ZFP E;  2LNX A;  4JGH A;  2L3T A;  2RMX A;  3KFJ A;  2ETZ A;  4QSY A;  2EYV A;  2L4K A;  2DVJ A;  2OZO A;  3VS7 A;  3K2M A;  4X6S A;  2YSX A;  4K44 A;  1AD5 A;  1D4T A;  4ROJ A;  3GXW A;  1FBV A;  1BKM A;  3OV1 A;  4JEG A;  1A1B A;  2CBL A;  3PQZ A;  3S9K A;  4K11 A;  4F5B A;  2AUG A;  1BM2 A;  1R1Q A;  5IBS A;  2IZV A;  3UF4 A;  3PFV A;  1CSY A;  3PLF B;  1JU5 A;  1H9O A;  1QCF A;  3EAC A;  2MC1 A;  1BLK A;  3K2T A;  2SHP A;  1UUS A;  4GWF A;  1QAD A;  4JE4 A;  1R1P A;  5AXI A;  1K9A A;  2MRK A;  4OHE A;  4WWQ A;  1YVL A;  5AUL A;  3VGO A;  5IBM A;  1GHU A;  1O4I A;  3IN8 A;  2BBU A;  1OPK A;  4XZ1 A;  3VRQ A;  4L1B B;  4A4B A;  5EG3 B;  3CXL A;  1A09 A;  1QG1 E;  2HCK A;  3CBL A;  1MW4 A;  1A1A A;  3CD3 A;  1NRV A;  2DX0 A;  2LRA A;  2H46 E;  3OP0 A;  3OB2 B;  5HKW A;  2PLD A;  3PSJ A;  4FBN A;  1SPS A;  1R1S A;  3S8N A;  1O47 A;  2XP1 A;  3IMJ A;  4XZ0 A;  1SHB A;  4FL3 A;  3VS2 A;  3US4 A;  1LUM A;  1Y57 A;  3ZNI A;  1SKJ A;  1O41 A;  3PS5 A;  2KNO A;  2SRC A;  1JYQ A;  2VIF A;  1HCT B;  3HCK A;  1I3Z A;  1Y1U A;  2H5K A;  1P13 A;  2CR4 A;  2LQN A;  1TZE E;  1O48 A;  3OB1 B;  1KA6 A;  1A1E A;  1FMK A;  4DGP A;  1O4R A;  4TZI A;  2HDX A;  2EO6 A;  2DLY A;  2FO0 A;  3VS5 A;  4E68 A;  1BFJ A;  2LCT A;  1X0N A;  2EU0 A;  1AB2 A;  1JYU A;  1RPY A;  4NWF A;  4FL2 A;  3VRN A;  4OHL A;  3BUO B;  3BUN B;  5BO4 A;  3N84 A;  3N7Y A;  1OO4 A;  1O49 A;  2DCR A;  5EEQ A;  1UUR A;  1FHS A;  2EO3 A;  3VRR A;  3BUM B;  3CWG A;  1O4K A;  2PNA A;  1SHD A;  1AOT F;  3PSK A;  2EKX A;  1BG1 A;  2CI8 A;  4EY0 A;  2C0I A;  2CI9 A;  1KC2 A;  5EHR A;  1O4H A;  1BMB A;  3MXC A;  1F1W A;  1AYD A;  1A08 A;  1IS0 A;  1BFI A;  2PNB A;  2GE9 A;  2ROR A;  1WQU A;  1LCJ A;  3TL0 A;  1CJ1 A;  2MK2 A;  2RVF A;  1FU5 A;  2JYQ A;  1O46 A;  3IN7 A;  2ECD A;  1A1C A;  4U17 A;  3QWY A;  1BHF A;  1MIL A;  1X6C A;  1AYA A;  5D0J A;  1GRI A;  2AOB A;  1O4B A;  3VS4 A;  2QMS A;  1A07 A;  1NZL A;  1LUN A;  1LUK A;  3NHN A;  1LUI A;  2Y1N A;  5HKZ A;  2DM0 A;  3C7I A;  3HHM B;  1BHH A;  2EYZ A;  2HDV A;  3OVE A;  3T04 A;  3VS3 A;  1NZV A;  1CWE A;  4GPL B;  1YVH A;  1O4A A;  1O4E A;  2CRH A;  1FYR A;  2K7A B;  1CSZ A;  3GXX A;  4D8K A;  2C9W A;  3IMD A;  2B3O A;  1A81 A;  1SHA A;  4P9V A;  1G83 A;  5EHP A;  3S8O A;  1B47 A;  1RQQ C;  3TKZ A;  1AOU F;  2PTK A;  3BKB A;  5DF6 A;  3VS1 A;  3QWX X;  5GJH A;  1BKL A;  4OHH A;  2Y1M A;  4OHI A;  1FBZ A;  4H1O A;  1TCE A;  4F59 A;  1O4O A;  1O4D A;  4U1P A;  2FCI A;  3VRZ A;  1O44 A;  3PJP A;  4P9Z A;  1O4J A;  5EEL A;  1IJR A;  5CDW A;  2IUI A;  5I6V A;  1OPL A;  2GSB A;  4GL9 E;  3VS0 A;  1KA7 A;  1LKL A;  1HCS B;  2DLZ A;  3M7F A;  2MQI A;  1LKK A;  3VRY A;  4A4C A;  4M4Z A;  2LQW A;  3GQI B;  1BHH B;  3N8M A;  1O4N A;  1O4Q A;  2Y3A B;  1X27 A;  3VS6 A;  2PLE A;  1RJA A;  2KGY A;  1AYC A;  1SPR A;  1JYR A;  4K2R A;  1CWD L;  1XA6 A;  4NWG A;  1O4P A;  1Z3K A;  1O4F A;  2RSY A;  5DC9 A;  1OO3 A;  1D1Z A;  1PIC A;  4LUE A;  4DGX A;  4E93 A;  2C0T A;  5J3X A;  1O4L A;  2YU7 A;  2HMH A;  1F2F A;  1M61 A;  1AYB A;  3S8L A;  3LYV A;  5KAZ A;  5HKY A;  1O45 A;  1FU6 A;  5DC4 A;  3WA4 A;  1LCK A;  5GJI A;  2HUW A;  2EYY A;  2EOB A;  1M27 A;  2K79 B;  1BF5 A;  2EL8 A;  3HIZ B;  4EIH A;  5DC0 B;  2CS0 A;  2H8H A;  2IUH A;  3MXY A; 
#chains in the Genus database with same CATH homology
 4OHD A;  1O4M A;  2MRJ A;  4F5A A;  1O42 A;  2OQ1 A;  2C0O A;  1JWO A;  3BUX B;  2IUG A;  3EAZ A;  3BUW B;  4LUD A;  3VRP A;  2KK6 A;  2CIA A;  3UYO A;  2AOA A;  1D4W A;  1KSW A;  1BLJ A;  1O4C A;  4H34 A;  3MAZ A;  2ABL A;  1O43 A;  2LNW A;  3VRO A;  2L6K A;  1O4G A;  4K45 A;  1ZFP E;  2LNX A;  4JGH A;  2L3T A;  2RMX A;  3KFJ A;  2ETZ A;  4QSY A;  2EYV A;  2L4K A;  2DVJ A;  2OZO A;  3VS7 A;  3K2M A;  4X6S A;  2YSX A;  4K44 A;  1AD5 A;  1D4T A;  4ROJ A;  3GXW A;  1FBV A;  1BKM A;  3OV1 A;  4JEG A;  1A1B A;  2CBL A;  3PQZ A;  3S9K A;  4K11 A;  4F5B A;  2AUG A;  1BM2 A;  1R1Q A;  5IBS A;  2IZV A;  3UF4 A;  3PFV A;  1CSY A;  3PLF B;  1JU5 A;  1H9O A;  1QCF A;  3EAC A;  2MC1 A;  1BLK A;  2SHP A;  1UUS A;  4GWF A;  1QAD A;  4JE4 A;  1R1P A;  5AXI A;  1K9A A;  2MRK A;  4OHE A;  4WWQ A;  1YVL A;  5AUL A;  3VGO A;  5IBM A;  1GHU A;  1O4I A;  3IN8 A;  2BBU A;  1OPK A;  4XZ1 A;  3VRQ A;  4L1B B;  4A4B A;  5EG3 B;  3CXL A;  1A09 A;  1QG1 E;  2HCK A;  3CBL A;  1MW4 A;  1A1A A;  3CD3 A;  1NRV A;  2DX0 A;  2H46 E;  3OP0 A;  3OB2 B;  5HKW A;  2PLD A;  3PSJ A;  4FBN A;  1SPS A;  1R1S A;  3S8N A;  1O47 A;  2XP1 A;  3IMJ A;  4XZ0 A;  1SHB A;  4FL3 A;  3VS2 A;  3US4 A;  1LUM A;  1Y57 A;  3ZNI A;  1SKJ A;  1O41 A;  3PS5 A;  2KNO A;  2SRC A;  1JYQ A;  2VIF A;  1HCT B;  3HCK A;  1I3Z A;  1Y1U A;  2H5K A;  1P13 A;  2CR4 A;  2LQN A;  1TZE E;  1O48 A;  3OB1 B;  1KA6 A;  1A1E A;  1FMK A;  4DGP A;  1O4R A;  4TZI A;  2HDX A;  2EO6 A;  2DLY A;  2FO0 A;  3VS5 A;  4E68 A;  1BFJ A;  2LCT A;  1X0N A;  2EU0 A;  1AB2 A;  1JYU A;  1RPY A;  4NWF A;  4FL2 A;  3VRN A;  4OHL A;  3BUO B;  3BUN B;  5BO4 A;  3N84 A;  3N7Y A;  1OO4 A;  1O49 A;  2DCR A;  5EEQ A;  1UUR A;  1FHS A;  2EO3 A;  3VRR A;  3BUM B;  3CWG A;  1O4K A;  2PNA A;  1SHD A;  1AOT F;  3PSK A;  2EKX A;  1BG1 A;  2CI8 A;  4EY0 A;  2C0I A;  2CI9 A;  1KC2 A;  5EHR A;  1O4H A;  1BMB A;  3MXC A;  1F1W A;  1AYD A;  1A08 A;  1IS0 A;  1BFI A;  2PNB A;  2GE9 A;  2ROR A;  1WQU A;  1LCJ A;  3TL0 A;  1CJ1 A;  2MK2 A;  2RVF A;  1FU5 A;  2JYQ A;  1O46 A;  3IN7 A;  2ECD A;  1A1C A;  4U17 A;  3QWY A;  1BHF A;  1MIL A;  1X6C A;  1AYA A;  5D0J A;  1GRI A;  2AOB A;  1O4B A;  3VS4 A;  2QMS A;  1A07 A;  1NZL A;  1LUN A;  1LUK A;  3NHN A;  1LUI A;  2Y1N A;  5HKZ A;  2DM0 A;  3C7I A;  3HHM B;  1BHH A;  2EYZ A;  2HDV A;  3OVE A;  3T04 A;  3VS3 A;  1NZV A;  1CWE A;  4GPL B;  1YVH A;  1O4A A;  1O4E A;  2CRH A;  1FYR A;  2K7A B;  1CSZ A;  3GXX A;  4D8K A;  2C9W A;  3IMD A;  2B3O A;  1A81 A;  1SHA A;  4P9V A;  1G83 A;  5EHP A;  3S8O A;  1B47 A;  1RQQ C;  3TKZ A;  1AOU F;  2PTK A;  3BKB A;  5DF6 A;  3VS1 A;  3QWX X;  5GJH A;  1BKL A;  4OHH A;  2Y1M A;  4OHI A;  1FBZ A;  4H1O A;  1TCE A;  4F59 A;  1O4O A;  1O4D A;  4U1P A;  2FCI A;  3VRZ A;  1O44 A;  3PJP A;  4P9Z A;  1O4J A;  5EEL A;  1IJR A;  5CDW A;  2IUI A;  5I6V A;  1OPL A;  2GSB A;  4GL9 E;  3VS0 A;  1KA7 A;  1LKL A;  1HCS B;  2DLZ A;  3M7F A;  2MQI A;  1LKK A;  3VRY A;  4A4C A;  4M4Z A;  2LQW A;  3GQI B;  1BHH B;  3N8M A;  1O4N A;  1O4Q A;  2Y3A B;  1X27 A;  3VS6 A;  2PLE A;  1RJA A;  1AYC A;  1SPR A;  1JYR A;  4K2R A;  1CWD L;  1XA6 A;  4NWG A;  1O4P A;  1Z3K A;  1O4F A;  2RSY A;  5DC9 A;  1OO3 A;  1D1Z A;  1PIC A;  4LUE A;  4DGX A;  4E93 A;  2C0T A;  5J3X A;  1O4L A;  2YU7 A;  2HMH A;  1F2F A;  1M61 A;  1AYB A;  3S8L A;  5KAZ A;  5HKY A;  1O45 A;  1FU6 A;  5DC4 A;  3WA4 A;  1LCK A;  5GJI A;  2HUW A;  2EYY A;  2EOB A;  1M27 A;  2K79 B;  1BF5 A;  2EL8 A;  3HIZ B;  4EIH A;  5DC0 B;  2CS0 A;  2H8H A;  2IUH A;  3MXY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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