3S8OA

Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
101
structure length
101
Chain Sequence
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
pubmed doi rcsb
molecule tags Signaling protein/antagonist
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2011-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3s8oA00
1WQUA 1AB2A 1D1ZA 2CIAA 1RPYA 2LQNA 4OHIA 4K11A 4A4BA 4LUEA 3HIZB 2FCIA 1JYUA 3US4A 2KNOA 3S9KA 1A07A 3VS0A 1RQQC 1RJAA 2DLYA 3BUOB 1GHUA 4FL2A 2AOAA 5D0JA 1CWEA 2PNBA 2DLZA 1M61A 5HKZA 1KA7A 1O44A 3GXXA 2L4KA 1HCSB 1BFIA 2AUGA 3VRZA 2PNAA 3PSJA 1FU5A 1A1EA 2PLEA 5EG3B 4E68A 3CXLA 1NRVA 4K2RA 5EEQA 1TCEA 4EIHA 2EYZA 1AYAA 1OO3A 2AOBA 5IBSA 4F59A 3VRYA 4U17A 4P9ZA 3VRPA 2GE9A 2MRKA 3S8NA 5GJHA 2IUIA 3EAZA 2LQWA 2DM0A 2C0OA 3N8MA 4H34A 1G83A 1OPLA 1O4CA 1NZVA 1OPKA 2GSBA 2DVJA 3PS5A 4K45A 1P13A 1O4BA 1O4IA 3GQIB 5HKYA 1K9AA 3QWXX 1MILA 3CWGA 3UF4A 4D8KA 1BG1A 1YVHA 2Y3AB 1BMBA 1O42A 1Y57A 1A81A 3OP0A 1A09A 3GXWA 3VS3A 4FL3A 4OHDA 2RVFA 3BKBA 2C9WA 2JYQA 3OV1A 4NWGA 1SHBA 4GL9E 1BFJA 1O45A 3BUNB 1JYQA 2HDXA 3TL0A 4F5AA 1O49A 1XA6A 2CBLA 2DCRA 1O4GA 2FO0A 2MK2A 2CS0A 4GWFA 3VGOA 1KSWA 1D4WA 3VS1A 1MW4A 3C7IA 2CI8A 1BHHB 1JWOA 2H8HA 2EYVA 1B47A 3VRNA 5IBMA 3M7FA 1M27A 2VIFA 1AOUF 1BKMA 2SHPA 5DC9A 3CD3A 1PICA 1R1PA 1O4JA 3MXYA 2EKXA 4H1OA 1BHFA 2ECDA 1R1QA 4FBNA 3VS4A 4OHHA 1QCFA 5I6VA 2CR4A 2Y1NA 5J3XA 3IN7A 1QADA 5GJIA 4DGPA 1O48A 2MQIA 3KFJA 1H9OA 2K7AB 2EO6A 3VRRA 3IN8A 3UYOA 2RSYA 2HMHA 1O4HA 2SRCA 2PLDA 3OB1B 1FMKA 3T04A 1CSZA 1FBVA 2EYYA 1O4DA 2L6KA 1A1BA 1SPSA 1GRIA 3IMJA 3HCKA 2XP1A 2HUWA 1O4RA 3NHNA 3VS2A 2YU7A 2RORA 2EU0A 1O4MA 1BLKA 2OZOA 1KC2A 1JU5A 1FBZA 3PQZA 2DX0A 4NWFA 2EOBA 4JGHA 1R1SA 2L3TA 1AOTF 1A08A 1BM2A 2BBUA 2KK6A 3VROA 4TZIA 3OB2B 3VS5A 3PFVA 5EHPA 1BHHA 2HDVA 3PJPA 3MXCA 1OO4A 1IJRA 1O4FA 3S8OA 1D4TA 4P9VA 4OHEA 3OVEA 5KAZA 1LUNA 2HCKA 4E93A 1O41A 4L1BB 1QG1E 5EHRA 1SKJA 2C0IA 4OHLA 1O4QA 1F2FA 5EELA 5BO4A 3PLFB 4XZ1A 5DC0B 4EY0A 2H46E 4X6SA 1O4AA 1O46A 1O4OA 3EACA 2PTKA 3QWYA 3VS6A 1O4PA 2OQ1A 1X6CA 4QSYA 1O4NA 1SPRA 1KA6A 4JE4A 4GPLB 1FHSA 1FYRA 1LUIA 1AYDA 5DF6A 1JYRA 1UUSA 1SHDA 3HHMB 3VS7A 2LNXA 1O47A 1CJ1A 1AYCA 1LCJA 1O4KA 2RMXA 2CRHA 4U1PA 5AXIA 5DC4A 1CSYA 1AD5A 3K2MA 1I3ZA 3IMDA 2LNWA 1LUMA 2IZVA 1X0NA 2EL8A 1A1CA 2YSXA 1TZEE 2IUGA 2K79B 1O4LA 1BLJA 4K44A 1CWDL 3N7YA 5HKWA 1ZFPE 2C0TA 5AULA 1LKLA 1BKLA 2QMSA 4DGXA 1LKKA 3BUWB 4ROJA 1AYBA 1SHAA 3BUMB 1UURA 2MRJA 1O43A 1YVLA 2ETZA 3TKZA 1F1WA 1LUKA 1IS0A 2Y1MA 3N84A 3PSKA 1BF5A 2H5KA 5CDWA 3CBLA 1HCTB 1Z3KA 1A1AA 1LCKA 1FU6A 1NZLA 3BUXB 3ZNIA 4LUDA 2CI9A 2IUHA 1X27A 2LCTA 2EO3A 4F5BA 1Y1UA 4M4ZA 4XZ0A 2ABLA 3WA4A 3MAZA 3S8LA 2B3OA 1O4EA 4WWQA 4A4CA 4JEGA 2MC1A 3VRQA
chains in the Genus database with same CATH superfamily
1WQUA 1AB2A 1D1ZA 2CIAA 1RPYA 2LQNA 4OHIA 4K11A 4A4BA 4LUEA 3HIZB 2FCIA 1JYUA 3US4A 2KNOA 3S9KA 1A07A 3VS0A 1RQQC 1RJAA 2DLYA 3BUOB 1GHUA 4FL2A 2AOAA 5D0JA 1CWEA 2PNBA 2DLZA 1M61A 5HKZA 1KA7A 1O44A 3GXXA 2L4KA 1HCSB 1BFIA 2AUGA 3VRZA 2PNAA 3PSJA 1FU5A 1A1EA 2PLEA 5EG3B 4E68A 3CXLA 1NRVA 4K2RA 5EEQA 1TCEA 4EIHA 2EYZA 1AYAA 1OO3A 2AOBA 5IBSA 4F59A 3VRYA 4U17A 4P9ZA 3VRPA 2GE9A 2MRKA 3LYVA 3S8NA 5GJHA 2IUIA 3EAZA 2LQWA 3VRQA 2DM0A 2C0OA 3N8MA 2KGYA 4H34A 1G83A 1OPLA 1O4CA 1NZVA 1OPKA 2GSBA 2DVJA 3PS5A 4K45A 1P13A 1O4BA 1O4IA 3GQIB 5HKYA 1K9AA 3QWXX 1MILA 3K2TA 3CWGA 3UF4A 4D8KA 1BG1A 1YVHA 2Y3AB 1BMBA 1O42A 1Y57A 1A81A 3OP0A 1A09A 3GXWA 3VS3A 4FL3A 4OHDA 2RVFA 3BKBA 2C9WA 2JYQA 3OV1A 4NWGA 1SHBA 4GL9E 1BFJA 1O45A 3BUNB 1JYQA 2HDXA 3TL0A 4F5AA 1O49A 1XA6A 2CBLA 2DCRA 1O4GA 2FO0A 2MK2A 2CS0A 4GWFA 3VGOA 1KSWA 1D4WA 3VS1A 1MW4A 3C7IA 2CI8A 1BHHB 1JWOA 2H8HA 2EYVA 1B47A 3VRNA 5IBMA 3M7FA 1M27A 2VIFA 1AOUF 1BKMA 2SHPA 5DC9A 3CD3A 1PICA 1R1PA 1O4JA 3MXYA 2EKXA 4H1OA 1BHFA 2ECDA 1R1QA 4FBNA 3VS4A 4OHHA 1QCFA 5I6VA 2CR4A 2Y1NA 5J3XA 3IN7A 1QADA 5GJIA 4DGPA 1O48A 2MQIA 3KFJA 1H9OA 2K7AB 2EO6A 3VRRA 3IN8A 3UYOA 2RSYA 2HMHA 1O4HA 2SRCA 2PLDA 3OB1B 1FMKA 3T04A 1CSZA 1FBVA 2EYYA 1O4DA 2L6KA 1A1BA 1SPSA 1GRIA 3IMJA 3HCKA 2XP1A 2HUWA 1O4RA 3NHNA 3VS2A 2YU7A 2RORA 2EU0A 1O4MA 1BLKA 2OZOA 1KC2A 1JU5A 1FBZA 3PQZA 2DX0A 4NWFA 2EOBA 4JGHA 1R1SA 2L3TA 1AOTF 1A08A 1BM2A 2BBUA 2KK6A 3VROA 4TZIA 3OB2B 3VS5A 3PFVA 5EHPA 1BHHA 2HDVA 3PJPA 3MXCA 1OO4A 1IJRA 1O4FA 3S8OA 1D4TA 4P9VA 4OHEA 3OVEA 5KAZA 1LUNA 2HCKA 4E93A 1O41A 4L1BB 1QG1E 5EHRA 1SKJA 2C0IA 4OHLA 1O4QA 1F2FA 5EELA 5BO4A 3PLFB 4XZ1A 5DC0B 4EY0A 2H46E 4X6SA 1O4AA 1O46A 1O4OA 3EACA 2PTKA 3QWYA 3VS6A 1O4PA 2OQ1A 1X6CA 4QSYA 1O4NA 1SPRA 1KA6A 4JE4A 4GPLB 1FHSA 1FYRA 1LUIA 1AYDA 5DF6A 1JYRA 1UUSA 1SHDA 3HHMB 3VS7A 2LNXA 1O47A 1CJ1A 1AYCA 1LCJA 1O4KA 2RMXA 2CRHA 4U1PA 5AXIA 5DC4A 1CSYA 1AD5A 3K2MA 1I3ZA 3IMDA 2LNWA 1LUMA 2IZVA 1X0NA 2EL8A 1A1CA 2YSXA 1TZEE 2IUGA 2K79B 1O4LA 1BLJA 4K44A 1CWDL 3N7YA 5HKWA 1ZFPE 2C0TA 5AULA 1LKLA 1BKLA 2QMSA 4DGXA 1LKKA 3BUWB 4ROJA 1AYBA 1SHAA 3BUMB 1UURA 2MRJA 1O43A 1YVLA 2ETZA 3TKZA 1F1WA 1LUKA 1IS0A 2Y1MA 3N84A 3PSKA 1BF5A 2H5KA 5CDWA 3CBLA 1HCTB 1Z3KA 1A1AA 1LCKA 1FU6A 1NZLA 3BUXB 3ZNIA 4LUDA 2CI9A 2IUHA 1X27A 2LCTA 2EO3A 4F5BA 1Y1UA 4M4ZA 4XZ0A 2ABLA 3WA4A 3MAZA 3S8LA 2B3OA 1O4EA 4WWQA 4A4CA 4JEGA 2MC1A 2LRAA
chains in the Genus database with same CATH topology
1WQUA 1AB2A 1D1ZA 2CIAA 1RPYA 2LQNA 4OHIA 4K11A 4A4BA 4LUEA 3HIZB 2FCIA 1JYUA 3US4A 2KNOA 3S9KA 1A07A 3VS0A 1RQQC 1RJAA 2DLYA 3BUOB 1GHUA 4FL2A 2AOAA 5D0JA 1CWEA 2PNBA 2DLZA 1M61A 5HKZA 1KA7A 1O44A 3GXXA 2L4KA 1HCSB 1BFIA 2AUGA 3VRZA 2PNAA 3PSJA 1FU5A 1A1EA 2PLEA 5EG3B 4E68A 3CXLA 1NRVA 4K2RA 5EEQA 1TCEA 4EIHA 2EYZA 1AYAA 1OO3A 2AOBA 5IBSA 4F59A 3VRYA 4U17A 4P9ZA 3VRPA 2GE9A 2MRKA 3S8NA 5GJHA 2IUIA 3EAZA 2LQWA 2DM0A 2C0OA 3N8MA 4H34A 1G83A 1OPLA 1O4CA 1NZVA 1OPKA 2GSBA 2DVJA 3PS5A 4K45A 1P13A 1O4BA 1O4IA 3GQIB 5HKYA 1K9AA 3QWXX 1MILA 3CWGA 3UF4A 4D8KA 1BG1A 1YVHA 2Y3AB 1BMBA 1O42A 1Y57A 1A81A 3OP0A 1A09A 3GXWA 3VS3A 4FL3A 4OHDA 2RVFA 3BKBA 2C9WA 2JYQA 3OV1A 4NWGA 1SHBA 4GL9E 1BFJA 1O45A 3BUNB 1JYQA 2HDXA 3TL0A 4F5AA 1O49A 1XA6A 2CBLA 2DCRA 1O4GA 2FO0A 2MK2A 2CS0A 4GWFA 3VGOA 1KSWA 1D4WA 3VS1A 1MW4A 3C7IA 2CI8A 1BHHB 1JWOA 2H8HA 2EYVA 1B47A 3VRNA 5IBMA 3M7FA 1M27A 2VIFA 1AOUF 1BKMA 2SHPA 5DC9A 3CD3A 1PICA 1R1PA 1O4JA 3MXYA 2EKXA 4H1OA 1BHFA 2ECDA 1R1QA 4FBNA 3VS4A 4OHHA 1QCFA 5I6VA 2CR4A 2Y1NA 5J3XA 3IN7A 1QADA 5GJIA 4DGPA 1O48A 2MQIA 3KFJA 1H9OA 2K7AB 2EO6A 3VRRA 3IN8A 3UYOA 2RSYA 2HMHA 1O4HA 2SRCA 2PLDA 3OB1B 1FMKA 3T04A 1CSZA 1FBVA 2EYYA 1O4DA 2L6KA 1A1BA 1SPSA 1GRIA 3IMJA 3HCKA 2XP1A 2HUWA 1O4RA 3NHNA 3VS2A 2YU7A 2RORA 2EU0A 1O4MA 1BLKA 2OZOA 1KC2A 1JU5A 1FBZA 3PQZA 2DX0A 4NWFA 2EOBA 4JGHA 1R1SA 2L3TA 1AOTF 1A08A 1BM2A 2BBUA 2KK6A 3VROA 4TZIA 3OB2B 3VS5A 3PFVA 5EHPA 1BHHA 2HDVA 3PJPA 3MXCA 1OO4A 1IJRA 1O4FA 3S8OA 1D4TA 4P9VA 4OHEA 3OVEA 5KAZA 1LUNA 2HCKA 4E93A 1O41A 4L1BB 1QG1E 5EHRA 1SKJA 2C0IA 4OHLA 1O4QA 1F2FA 5EELA 5BO4A 3PLFB 4XZ1A 5DC0B 4EY0A 2H46E 4X6SA 1O4AA 1O46A 1O4OA 3EACA 2PTKA 3QWYA 3VS6A 1O4PA 2OQ1A 1X6CA 4QSYA 1O4NA 1SPRA 1KA6A 4JE4A 4GPLB 1FHSA 1FYRA 1LUIA 1AYDA 5DF6A 1JYRA 1UUSA 1SHDA 3HHMB 3VS7A 2LNXA 1O47A 1CJ1A 1AYCA 1LCJA 1O4KA 2RMXA 2CRHA 4U1PA 5AXIA 5DC4A 1CSYA 1AD5A 3K2MA 1I3ZA 3IMDA 2LNWA 1LUMA 2IZVA 1X0NA 2EL8A 1A1CA 2YSXA 1TZEE 2IUGA 2K79B 1O4LA 1BLJA 4K44A 1CWDL 3N7YA 5HKWA 1ZFPE 2C0TA 5AULA 1LKLA 1BKLA 2QMSA 4DGXA 1LKKA 3BUWB 4ROJA 1AYBA 1SHAA 3BUMB 1UURA 2MRJA 1O43A 1YVLA 2ETZA 3TKZA 1F1WA 1LUKA 1IS0A 2Y1MA 3N84A 3PSKA 1BF5A 2H5KA 5CDWA 3CBLA 1HCTB 1Z3KA 1A1AA 1LCKA 1FU6A 1NZLA 3BUXB 3ZNIA 4LUDA 2CI9A 2IUHA 1X27A 2LCTA 2EO3A 4F5BA 1Y1UA 4M4ZA 4XZ0A 2ABLA 3WA4A 3MAZA 3S8LA 2B3OA 1O4EA 4WWQA 4A4CA 4JEGA 2MC1A 3VRQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQU A;  1AB2 A;  1D1Z A;  2CIA A;  1RPY A;  2LQN A;  4OHI A;  4K11 A;  4A4B A;  4LUE A;  3HIZ B;  2FCI A;  1JYU A;  3US4 A;  2KNO A;  3S9K A;  1A07 A;  3VS0 A;  1RQQ C;  1RJA A;  2DLY A;  3BUO B;  1GHU A;  4FL2 A;  2AOA A;  5D0J A;  1CWE A;  2PNB A;  2DLZ A;  1M61 A;  5HKZ A;  1KA7 A;  1O44 A;  3GXX A;  2L4K A;  1HCS B;  1BFI A;  2AUG A;  3VRZ A;  2PNA A;  3PSJ A;  1FU5 A;  1A1E A;  2PLE A;  5EG3 B;  4E68 A;  3CXL A;  1NRV A;  4K2R A;  5EEQ A;  1TCE A;  4EIH A;  2EYZ A;  1AYA A;  1OO3 A;  2AOB A;  5IBS A;  4F59 A;  3VRY A;  4U17 A;  4P9Z A;  3VRP A;  2GE9 A;  2MRK A;  3S8N A;  5GJH A;  2IUI A;  3EAZ A;  2LQW A;  2DM0 A;  2C0O A;  3N8M A;  4H34 A;  1G83 A;  1OPL A;  1O4C A;  1NZV A;  1OPK A;  2GSB A;  2DVJ A;  3PS5 A;  4K45 A;  1P13 A;  1O4B A;  1O4I A;  3GQI B;  5HKY A;  1K9A A;  3QWX X;  1MIL A;  3CWG A;  3UF4 A;  4D8K A;  1BG1 A;  1YVH A;  2Y3A B;  1BMB A;  1O42 A;  1Y57 A;  1A81 A;  3OP0 A;  1A09 A;  3GXW A;  3VS3 A;  4FL3 A;  4OHD A;  2RVF A;  3BKB A;  2C9W A;  2JYQ A;  3OV1 A;  4NWG A;  1SHB A;  4GL9 E;  1BFJ A;  1O45 A;  3BUN B;  1JYQ A;  2HDX A;  3TL0 A;  4F5A A;  1O49 A;  1XA6 A;  2CBL A;  2DCR A;  1O4G A;  2FO0 A;  2MK2 A;  2CS0 A;  4GWF A;  3VGO A;  1KSW A;  1D4W A;  3VS1 A;  1MW4 A;  3C7I A;  2CI8 A;  1BHH B;  1JWO A;  2H8H A;  2EYV A;  1B47 A;  3VRN A;  5IBM A;  3M7F A;  1M27 A;  2VIF A;  1AOU F;  1BKM A;  2SHP A;  5DC9 A;  3CD3 A;  1PIC A;  1R1P A;  1O4J A;  3MXY A;  2EKX A;  4H1O A;  1BHF A;  2ECD A;  1R1Q A;  4FBN A;  3VS4 A;  4OHH A;  1QCF A;  5I6V A;  2CR4 A;  2Y1N A;  5J3X A;  3IN7 A;  1QAD A;  5GJI A;  4DGP A;  1O48 A;  2MQI A;  3KFJ A;  1H9O A;  2K7A B;  2EO6 A;  3VRR A;  3IN8 A;  3UYO A;  2RSY A;  2HMH A;  1O4H A;  2SRC A;  2PLD A;  3OB1 B;  1FMK A;  3T04 A;  1CSZ A;  1FBV A;  2EYY A;  1O4D A;  2L6K A;  1A1B A;  1SPS A;  1GRI A;  3IMJ A;  3HCK A;  2XP1 A;  2HUW A;  1O4R A;  3NHN A;  3VS2 A;  2YU7 A;  2ROR A;  2EU0 A;  1O4M A;  1BLK A;  2OZO A;  1KC2 A;  1JU5 A;  1FBZ A;  3PQZ A;  2DX0 A;  4NWF A;  2EOB A;  4JGH A;  1R1S A;  2L3T A;  1AOT F;  1A08 A;  1BM2 A;  2BBU A;  2KK6 A;  3VRO A;  4TZI A;  3OB2 B;  3VS5 A;  3PFV A;  5EHP A;  1BHH A;  2HDV A;  3PJP A;  3MXC A;  1OO4 A;  1IJR A;  1O4F A;  3S8O A;  1D4T A;  4P9V A;  4OHE A;  3OVE A;  5KAZ A;  1LUN A;  2HCK A;  4E93 A;  1O41 A;  4L1B B;  1QG1 E;  5EHR A;  1SKJ A;  2C0I A;  4OHL A;  1O4Q A;  1F2F A;  5EEL A;  5BO4 A;  3PLF B;  4XZ1 A;  5DC0 B;  4EY0 A;  2H46 E;  4X6S A;  1O4A A;  1O46 A;  1O4O A;  3EAC A;  2PTK A;  3QWY A;  3VS6 A;  1O4P A;  2OQ1 A;  1X6C A;  4QSY A;  1O4N A;  1SPR A;  1KA6 A;  4JE4 A;  4GPL B;  1FHS A;  1FYR A;  1LUI A;  1AYD A;  5DF6 A;  1JYR A;  1UUS A;  1SHD A;  3HHM B;  3VS7 A;  2LNX A;  1O47 A;  1CJ1 A;  1AYC A;  1LCJ A;  1O4K A;  2RMX A;  2CRH A;  4U1P A;  5AXI A;  5DC4 A;  1CSY A;  1AD5 A;  3K2M A;  1I3Z A;  3IMD A;  2LNW A;  1LUM A;  2IZV A;  1X0N A;  2EL8 A;  1A1C A;  2YSX A;  1TZE E;  2IUG A;  2K79 B;  1O4L A;  1BLJ A;  4K44 A;  1CWD L;  3N7Y A;  5HKW A;  1ZFP E;  2C0T A;  5AUL A;  1LKL A;  1BKL A;  2QMS A;  4DGX A;  1LKK A;  3BUW B;  4ROJ A;  1AYB A;  1SHA A;  3BUM B;  1UUR A;  2MRJ A;  1O43 A;  1YVL A;  2ETZ A;  3TKZ A;  1F1W A;  1LUK A;  1IS0 A;  2Y1M A;  3N84 A;  3PSK A;  1BF5 A;  2H5K A;  5CDW A;  3CBL A;  1HCT B;  1Z3K A;  1A1A A;  1LCK A;  1FU6 A;  1NZL A;  3BUX B;  3ZNI A;  4LUD A;  2CI9 A;  2IUH A;  1X27 A;  2LCT A;  2EO3 A;  4F5B A;  1Y1U A;  4M4Z A;  4XZ0 A;  2ABL A;  3WA4 A;  3MAZ A;  3S8L A;  2B3O A;  1O4E A;  4WWQ A;  4A4C A;  4JEG A;  2MC1 A;  3VRQ A; 
#chains in the Genus database with same CATH topology
 1WQU A;  1AB2 A;  1D1Z A;  2CIA A;  1RPY A;  2LQN A;  4OHI A;  4K11 A;  4A4B A;  4LUE A;  3HIZ B;  2FCI A;  1JYU A;  3US4 A;  2KNO A;  3S9K A;  1A07 A;  3VS0 A;  1RQQ C;  1RJA A;  2DLY A;  3BUO B;  1GHU A;  4FL2 A;  2AOA A;  5D0J A;  1CWE A;  2PNB A;  2DLZ A;  1M61 A;  5HKZ A;  1KA7 A;  1O44 A;  3GXX A;  2L4K A;  1HCS B;  1BFI A;  2AUG A;  3VRZ A;  2PNA A;  3PSJ A;  1FU5 A;  1A1E A;  2PLE A;  5EG3 B;  4E68 A;  3CXL A;  1NRV A;  4K2R A;  5EEQ A;  1TCE A;  4EIH A;  2EYZ A;  1AYA A;  1OO3 A;  2AOB A;  5IBS A;  4F59 A;  3VRY A;  4U17 A;  4P9Z A;  3VRP A;  2GE9 A;  2MRK A;  3LYV A;  3S8N A;  5GJH A;  2IUI A;  3EAZ A;  2LQW A;  3VRQ A;  2DM0 A;  2C0O A;  3N8M A;  2KGY A;  4H34 A;  1G83 A;  1OPL A;  1O4C A;  1NZV A;  1OPK A;  2GSB A;  2DVJ A;  3PS5 A;  4K45 A;  1P13 A;  1O4B A;  1O4I A;  3GQI B;  5HKY A;  1K9A A;  3QWX X;  1MIL A;  3K2T A;  3CWG A;  3UF4 A;  4D8K A;  1BG1 A;  1YVH A;  2Y3A B;  1BMB A;  1O42 A;  1Y57 A;  1A81 A;  3OP0 A;  1A09 A;  3GXW A;  3VS3 A;  4FL3 A;  4OHD A;  2RVF A;  3BKB A;  2C9W A;  2JYQ A;  3OV1 A;  4NWG A;  1SHB A;  4GL9 E;  1BFJ A;  1O45 A;  3BUN B;  1JYQ A;  2HDX A;  3TL0 A;  4F5A A;  1O49 A;  1XA6 A;  2CBL A;  2DCR A;  1O4G A;  2FO0 A;  2MK2 A;  2CS0 A;  4GWF A;  3VGO A;  1KSW A;  1D4W A;  3VS1 A;  1MW4 A;  3C7I A;  2CI8 A;  1BHH B;  1JWO A;  2H8H A;  2EYV A;  1B47 A;  3VRN A;  5IBM A;  3M7F A;  1M27 A;  2VIF A;  1AOU F;  1BKM A;  2SHP A;  5DC9 A;  3CD3 A;  1PIC A;  1R1P A;  1O4J A;  3MXY A;  2EKX A;  4H1O A;  1BHF A;  2ECD A;  1R1Q A;  4FBN A;  3VS4 A;  4OHH A;  1QCF A;  5I6V A;  2CR4 A;  2Y1N A;  5J3X A;  3IN7 A;  1QAD A;  5GJI A;  4DGP A;  1O48 A;  2MQI A;  3KFJ A;  1H9O A;  2K7A B;  2EO6 A;  3VRR A;  3IN8 A;  3UYO A;  2RSY A;  2HMH A;  1O4H A;  2SRC A;  2PLD A;  3OB1 B;  1FMK A;  3T04 A;  1CSZ A;  1FBV A;  2EYY A;  1O4D A;  2L6K A;  1A1B A;  1SPS A;  1GRI A;  3IMJ A;  3HCK A;  2XP1 A;  2HUW A;  1O4R A;  3NHN A;  3VS2 A;  2YU7 A;  2ROR A;  2EU0 A;  1O4M A;  1BLK A;  2OZO A;  1KC2 A;  1JU5 A;  1FBZ A;  3PQZ A;  2DX0 A;  4NWF A;  2EOB A;  4JGH A;  1R1S A;  2L3T A;  1AOT F;  1A08 A;  1BM2 A;  2BBU A;  2KK6 A;  3VRO A;  4TZI A;  3OB2 B;  3VS5 A;  3PFV A;  5EHP A;  1BHH A;  2HDV A;  3PJP A;  3MXC A;  1OO4 A;  1IJR A;  1O4F A;  3S8O A;  1D4T A;  4P9V A;  4OHE A;  3OVE A;  5KAZ A;  1LUN A;  2HCK A;  4E93 A;  1O41 A;  4L1B B;  1QG1 E;  5EHR A;  1SKJ A;  2C0I A;  4OHL A;  1O4Q A;  1F2F A;  5EEL A;  5BO4 A;  3PLF B;  4XZ1 A;  5DC0 B;  4EY0 A;  2H46 E;  4X6S A;  1O4A A;  1O46 A;  1O4O A;  3EAC A;  2PTK A;  3QWY A;  3VS6 A;  1O4P A;  2OQ1 A;  1X6C A;  4QSY A;  1O4N A;  1SPR A;  1KA6 A;  4JE4 A;  4GPL B;  1FHS A;  1FYR A;  1LUI A;  1AYD A;  5DF6 A;  1JYR A;  1UUS A;  1SHD A;  3HHM B;  3VS7 A;  2LNX A;  1O47 A;  1CJ1 A;  1AYC A;  1LCJ A;  1O4K A;  2RMX A;  2CRH A;  4U1P A;  5AXI A;  5DC4 A;  1CSY A;  1AD5 A;  3K2M A;  1I3Z A;  3IMD A;  2LNW A;  1LUM A;  2IZV A;  1X0N A;  2EL8 A;  1A1C A;  2YSX A;  1TZE E;  2IUG A;  2K79 B;  1O4L A;  1BLJ A;  4K44 A;  1CWD L;  3N7Y A;  5HKW A;  1ZFP E;  2C0T A;  5AUL A;  1LKL A;  1BKL A;  2QMS A;  4DGX A;  1LKK A;  3BUW B;  4ROJ A;  1AYB A;  1SHA A;  3BUM B;  1UUR A;  2MRJ A;  1O43 A;  1YVL A;  2ETZ A;  3TKZ A;  1F1W A;  1LUK A;  1IS0 A;  2Y1M A;  3N84 A;  3PSK A;  1BF5 A;  2H5K A;  5CDW A;  3CBL A;  1HCT B;  1Z3K A;  1A1A A;  1LCK A;  1FU6 A;  1NZL A;  3BUX B;  3ZNI A;  4LUD A;  2CI9 A;  2IUH A;  1X27 A;  2LCT A;  2EO3 A;  4F5B A;  1Y1U A;  4M4Z A;  4XZ0 A;  2ABL A;  3WA4 A;  3MAZ A;  3S8L A;  2B3O A;  1O4E A;  4WWQ A;  4A4C A;  4JEG A;  2MC1 A;  2LRA A; 
#chains in the Genus database with same CATH homology
 1WQU A;  1AB2 A;  1D1Z A;  2CIA A;  1RPY A;  2LQN A;  4OHI A;  4K11 A;  4A4B A;  4LUE A;  3HIZ B;  2FCI A;  1JYU A;  3US4 A;  2KNO A;  3S9K A;  1A07 A;  3VS0 A;  1RQQ C;  1RJA A;  2DLY A;  3BUO B;  1GHU A;  4FL2 A;  2AOA A;  5D0J A;  1CWE A;  2PNB A;  2DLZ A;  1M61 A;  5HKZ A;  1KA7 A;  1O44 A;  3GXX A;  2L4K A;  1HCS B;  1BFI A;  2AUG A;  3VRZ A;  2PNA A;  3PSJ A;  1FU5 A;  1A1E A;  2PLE A;  5EG3 B;  4E68 A;  3CXL A;  1NRV A;  4K2R A;  5EEQ A;  1TCE A;  4EIH A;  2EYZ A;  1AYA A;  1OO3 A;  2AOB A;  5IBS A;  4F59 A;  3VRY A;  4U17 A;  4P9Z A;  3VRP A;  2GE9 A;  2MRK A;  3S8N A;  5GJH A;  2IUI A;  3EAZ A;  2LQW A;  2DM0 A;  2C0O A;  3N8M A;  4H34 A;  1G83 A;  1OPL A;  1O4C A;  1NZV A;  1OPK A;  2GSB A;  2DVJ A;  3PS5 A;  4K45 A;  1P13 A;  1O4B A;  1O4I A;  3GQI B;  5HKY A;  1K9A A;  3QWX X;  1MIL A;  3CWG A;  3UF4 A;  4D8K A;  1BG1 A;  1YVH A;  2Y3A B;  1BMB A;  1O42 A;  1Y57 A;  1A81 A;  3OP0 A;  1A09 A;  3GXW A;  3VS3 A;  4FL3 A;  4OHD A;  2RVF A;  3BKB A;  2C9W A;  2JYQ A;  3OV1 A;  4NWG A;  1SHB A;  4GL9 E;  1BFJ A;  1O45 A;  3BUN B;  1JYQ A;  2HDX A;  3TL0 A;  4F5A A;  1O49 A;  1XA6 A;  2CBL A;  2DCR A;  1O4G A;  2FO0 A;  2MK2 A;  2CS0 A;  4GWF A;  3VGO A;  1KSW A;  1D4W A;  3VS1 A;  1MW4 A;  3C7I A;  2CI8 A;  1BHH B;  1JWO A;  2H8H A;  2EYV A;  1B47 A;  3VRN A;  5IBM A;  3M7F A;  1M27 A;  2VIF A;  1AOU F;  1BKM A;  2SHP A;  5DC9 A;  3CD3 A;  1PIC A;  1R1P A;  1O4J A;  3MXY A;  2EKX A;  4H1O A;  1BHF A;  2ECD A;  1R1Q A;  4FBN A;  3VS4 A;  4OHH A;  1QCF A;  5I6V A;  2CR4 A;  2Y1N A;  5J3X A;  3IN7 A;  1QAD A;  5GJI A;  4DGP A;  1O48 A;  2MQI A;  3KFJ A;  1H9O A;  2K7A B;  2EO6 A;  3VRR A;  3IN8 A;  3UYO A;  2RSY A;  2HMH A;  1O4H A;  2SRC A;  2PLD A;  3OB1 B;  1FMK A;  3T04 A;  1CSZ A;  1FBV A;  2EYY A;  1O4D A;  2L6K A;  1A1B A;  1SPS A;  1GRI A;  3IMJ A;  3HCK A;  2XP1 A;  2HUW A;  1O4R A;  3NHN A;  3VS2 A;  2YU7 A;  2ROR A;  2EU0 A;  1O4M A;  1BLK A;  2OZO A;  1KC2 A;  1JU5 A;  1FBZ A;  3PQZ A;  2DX0 A;  4NWF A;  2EOB A;  4JGH A;  1R1S A;  2L3T A;  1AOT F;  1A08 A;  1BM2 A;  2BBU A;  2KK6 A;  3VRO A;  4TZI A;  3OB2 B;  3VS5 A;  3PFV A;  5EHP A;  1BHH A;  2HDV A;  3PJP A;  3MXC A;  1OO4 A;  1IJR A;  1O4F A;  3S8O A;  1D4T A;  4P9V A;  4OHE A;  3OVE A;  5KAZ A;  1LUN A;  2HCK A;  4E93 A;  1O41 A;  4L1B B;  1QG1 E;  5EHR A;  1SKJ A;  2C0I A;  4OHL A;  1O4Q A;  1F2F A;  5EEL A;  5BO4 A;  3PLF B;  4XZ1 A;  5DC0 B;  4EY0 A;  2H46 E;  4X6S A;  1O4A A;  1O46 A;  1O4O A;  3EAC A;  2PTK A;  3QWY A;  3VS6 A;  1O4P A;  2OQ1 A;  1X6C A;  4QSY A;  1O4N A;  1SPR A;  1KA6 A;  4JE4 A;  4GPL B;  1FHS A;  1FYR A;  1LUI A;  1AYD A;  5DF6 A;  1JYR A;  1UUS A;  1SHD A;  3HHM B;  3VS7 A;  2LNX A;  1O47 A;  1CJ1 A;  1AYC A;  1LCJ A;  1O4K A;  2RMX A;  2CRH A;  4U1P A;  5AXI A;  5DC4 A;  1CSY A;  1AD5 A;  3K2M A;  1I3Z A;  3IMD A;  2LNW A;  1LUM A;  2IZV A;  1X0N A;  2EL8 A;  1A1C A;  2YSX A;  1TZE E;  2IUG A;  2K79 B;  1O4L A;  1BLJ A;  4K44 A;  1CWD L;  3N7Y A;  5HKW A;  1ZFP E;  2C0T A;  5AUL A;  1LKL A;  1BKL A;  2QMS A;  4DGX A;  1LKK A;  3BUW B;  4ROJ A;  1AYB A;  1SHA A;  3BUM B;  1UUR A;  2MRJ A;  1O43 A;  1YVL A;  2ETZ A;  3TKZ A;  1F1W A;  1LUK A;  1IS0 A;  2Y1M A;  3N84 A;  3PSK A;  1BF5 A;  2H5K A;  5CDW A;  3CBL A;  1HCT B;  1Z3K A;  1A1A A;  1LCK A;  1FU6 A;  1NZL A;  3BUX B;  3ZNI A;  4LUD A;  2CI9 A;  2IUH A;  1X27 A;  2LCT A;  2EO3 A;  4F5B A;  1Y1U A;  4M4Z A;  4XZ0 A;  2ABL A;  3WA4 A;  3MAZ A;  3S8L A;  2B3O A;  1O4E A;  4WWQ A;  4A4C A;  4JEG A;  2MC1 A;  3VRQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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