3TKZA

Structure of the shp-2 n-sh2 domain in a 1:2 complex with rvipyfvplnr peptide
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
100
structure length
100
Chain Sequence
RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
pubmed doi rcsb
molecule tags Hydrolase/peptide
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 23
structure length 100
sequence length 100
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3tkzA00
1O49A 2PLDA 1ZFPE 1RQQC 3T04A 3UYOA 1O4CA 4OHIA 2RMXA 1AYDA 2K79B 1IS0A 1IJRA 4M4ZA 3HCKA 1O44A 4ROJA 2CS0A 1NRVA 1LUMA 4JEGA 3S9KA 2HMHA 2AOAA 1FU6A 3VS4A 3OB1B 3N7YA 5CDWA 1BHFA 3EAZA 2GE9A 1O4IA 2B3OA 2HDVA 1LKLA 2MRKA 1F1WA 1FMKA 4F59A 4FBNA 3GXXA 1CJ1A 5IBMA 1SHAA 2PNBA 4H1OA 2FCIA 3PQZA 4A4CA 3VGOA 2H5KA 2MK2A 1R1SA 1A1CA 2MQIA 4NWFA 4FL2A 1BMBA 2DM0A 4F5AA 2KK6A 3PSJA 2EU0A 2PTKA 1O4NA 4U1PA 3CWGA 1LKKA 2EO3A 3GQIB 1AOTF 1FBVA 2YU7A 3S8NA 1O42A 5DC9A 2Y1MA 2EYZA 2Y1NA 1PICA 1LCJA 1O45A 2EL8A 1OO3A 1P13A 2HDXA 3KFJA 2AUGA 1O4EA 3PJPA 2LNWA 3BUXB 3WA4A 1D4WA 2CR4A 1QADA 4FL3A 1O4LA 1O4AA 3VS7A 1CSZA 4OHHA 2AOBA 4K44A 4WWQA 1QG1E 2K7AB 1BF5A 3EACA 1LCKA 1A07A 2GSBA 1GRIA 2YSXA 1JYQA 2C0TA 4LUDA 1NZLA 1A81A 1O4OA 2CRHA 1SPSA 4K2RA 3VROA 1CWDL 2CI8A 2LQNA 2IUIA 1CWEA 1BFIA 1A1BA 1BKMA 3PSKA 3K2MA 2C9WA 1AYBA 4F5BA 1H9OA 1JU5A 2L4KA 4JGHA 3VS6A 4OHLA 5EELA 3CBLA 2PNAA 3MXYA 3VS2A 1JYRA 4EY0A 3VRRA 4A4BA 3OB2B 5HKYA 2CIAA 5EEQA 3IMDA 1FBZA 3OVEA 1TCEA 4DGPA 3BUOB 3VS0A 2ETZA 1WQUA 1RPYA 3IMJA 1X6CA 1BFJA 4QSYA 5DF6A 4L1BB 1JWOA 2IUHA 1HCSB 2DLYA 1UUSA 3US4A 1YVLA 1O4HA 2XP1A 3N8MA 2DLZA 2HUWA 2PLEA 1UURA 2QMSA 1OPKA 4OHDA 4XZ0A 1O4FA 1A1EA 1BG1A 1XA6A 1CSYA 1FYRA 1AYAA 1O4QA 3PS5A 2SHPA 1LUKA 1Y1UA 4U17A 5EHRA 4OHEA 3BUMB 1O48A 4XZ1A 2VIFA 2RVFA 2ECDA 4GWFA 3VRQA 1TZEE 2MC1A 4LUEA 3IN7A 4P9VA 2H8HA 2ABLA 4E68A 3ZNIA 5I6VA 1MW4A 1X27A 1A1AA 5HKWA 2KNOA 5AXIA 3PLFB 3OP0A 2C0IA 1G83A 3CD3A 2L6KA 5IBSA 3VRYA 1BHHB 2DCRA 1O47A 2LCTA 1D1ZA 3OV1A 1X0NA 3HIZB 1D4TA 2L3TA 4E93A 3CXLA 2OZOA 5KAZA 3QWXX 1O4GA 4GL9E 3VRNA 1R1QA 3PFVA 3QWYA 3S8OA 1O4PA 2LNXA 5BO4A 3IN8A 1O41A 1A09A 3MAZA 2LQWA 1BLKA 3VRPA 1BM2A 5GJIA 2IUGA 1K9AA 1M27A 1KSWA 5EG3B 1FU5A 1SPRA 1LUNA 2CI9A 1FHSA 5HKZA 2EO6A 3TL0A 1GHUA 1O4RA 5DC0B 1SHBA 1OPLA 1O4KA 2OQ1A 1O4BA 2HCKA 2RORA 3VRZA 4JE4A 2Y3AB 1LUIA 4P9ZA 3GXWA 1NZVA 4D8KA 1KC2A 2EYYA 2IZVA 1O4JA 4K11A 4TZIA 1SHDA 1O43A 3BUWB 2H46E 3BUNB 3MXCA 1MILA 1SKJA 1BLJA 1I3ZA 5D0JA 4EIHA 5GJHA 1Y57A 3C7IA 3NHNA 1AOUF 3HHMB 2JYQA 1BKLA 2FO0A 2EKXA 3M7FA 3VS5A 1JYUA 4K45A 4NWGA 1AB2A 3N84A 5J3XA 3VS1A 2DVJA 3UF4A 1B47A 4X6SA 4H34A 1OO4A 1F2FA 2BBUA 2CBLA 3VS3A 1AYCA 1O4MA 1M61A 3TKZA 4GPLB 1AD5A 2MRJA 2EOBA 5AULA 1O46A 1KA6A 3S8LA 5DC4A 1R1PA 5EHPA 2EYVA 1RJAA 4DGXA 2SRCA 1HCTB 1KA7A 2RSYA 1QCFA 1A08A 1BHHA 1YVHA 1Z3KA 3BKBA 1O4DA 2C0OA 2DX0A
chains in the Genus database with same CATH superfamily
1O49A 2PLDA 1ZFPE 1RQQC 3T04A 3UYOA 1O4CA 4OHIA 2RMXA 1AYDA 2K79B 1IS0A 1IJRA 4M4ZA 3HCKA 1O44A 4ROJA 2CS0A 1NRVA 1LUMA 4JEGA 3S9KA 2HMHA 2AOAA 1FU6A 3VS4A 3OB1B 3N7YA 5CDWA 1BHFA 3EAZA 2GE9A 1O4IA 2B3OA 2HDVA 1LKLA 2MRKA 1F1WA 1FMKA 4F59A 4FBNA 3GXXA 1CJ1A 5IBMA 3LYVA 1SHAA 2PNBA 4H1OA 2FCIA 3PQZA 4A4CA 3VGOA 2H5KA 2MK2A 1R1SA 1A1CA 2MQIA 4NWFA 4FL2A 1BMBA 2DM0A 4F5AA 2KK6A 3PSJA 2EU0A 2PTKA 2LRAA 1O4NA 4U1PA 3CWGA 1LKKA 2EO3A 3GQIB 1AOTF 1FBVA 2YU7A 3S8NA 1O42A 5DC9A 2Y1MA 2EYZA 2Y1NA 1PICA 1LCJA 1O45A 2EL8A 1OO3A 1P13A 2HDXA 3KFJA 2AUGA 1O4EA 3PJPA 2LNWA 3BUXB 3WA4A 1D4WA 2CR4A 1QADA 4FL3A 1O4LA 1O4AA 3VS7A 1CSZA 4OHHA 2AOBA 4K44A 4WWQA 1QG1E 2K7AB 1BF5A 3EACA 1LCKA 1A07A 2GSBA 1GRIA 2YSXA 1JYQA 2C0TA 4LUDA 1NZLA 1A81A 1O4OA 2CRHA 1SPSA 4K2RA 3VROA 1CWDL 2CI8A 2LQNA 2IUIA 1CWEA 1BFIA 1A1BA 1BKMA 3PSKA 3K2MA 2C9WA 1AYBA 4F5BA 1H9OA 1JU5A 2L4KA 4JGHA 3VS6A 4OHLA 5EELA 3CBLA 2PNAA 3MXYA 3VS2A 1JYRA 4EY0A 3VRRA 4A4BA 3OB2B 5HKYA 2CIAA 5EEQA 3IMDA 1FBZA 3OVEA 1TCEA 4DGPA 3BUOB 3VS0A 2ETZA 1WQUA 1RPYA 3IMJA 1X6CA 1BFJA 4QSYA 5DF6A 4L1BB 1JWOA 2IUHA 1HCSB 2DLYA 1UUSA 3US4A 1YVLA 1O4HA 2XP1A 3N8MA 2DLZA 2HUWA 2PLEA 1UURA 2QMSA 1OPKA 4OHDA 4XZ0A 1O4FA 1A1EA 1BG1A 1XA6A 1CSYA 1FYRA 1AYAA 1O4QA 3PS5A 2SHPA 1LUKA 1Y1UA 4U17A 5EHRA 4OHEA 3BUMB 1O48A 4XZ1A 2VIFA 2RVFA 2ECDA 4GWFA 3VRQA 1TZEE 2MC1A 4LUEA 3IN7A 4P9VA 2H8HA 2ABLA 4E68A 3ZNIA 5I6VA 1MW4A 1X27A 1A1AA 5HKWA 2KNOA 5AXIA 3PLFB 3OP0A 2C0IA 1G83A 3CD3A 2L6KA 5IBSA 3VRYA 1BHHB 2DCRA 1O47A 2LCTA 1D1ZA 3OV1A 1X0NA 3HIZB 1D4TA 2L3TA 4E93A 3CXLA 2OZOA 5KAZA 3QWXX 1O4GA 4GL9E 3VRNA 1R1QA 3PFVA 3QWYA 3S8OA 1O4PA 2LNXA 5BO4A 3IN8A 1O41A 1A09A 3MAZA 2LQWA 1BLKA 3K2TA 3VRPA 1BM2A 5GJIA 2KGYA 2IUGA 1K9AA 1M27A 1KSWA 5EG3B 1FU5A 1SPRA 1LUNA 2CI9A 1FHSA 5HKZA 2EO6A 3TL0A 1GHUA 1O4RA 5DC0B 1SHBA 1OPLA 1O4KA 2OQ1A 1O4BA 2HCKA 2RORA 3VRZA 4JE4A 2Y3AB 1LUIA 4P9ZA 3GXWA 1NZVA 4D8KA 1KC2A 2EYYA 2IZVA 1O4JA 4K11A 4TZIA 1SHDA 1O43A 3BUWB 2H46E 3BUNB 3MXCA 1MILA 1SKJA 1BLJA 1I3ZA 5D0JA 4EIHA 5GJHA 1Y57A 3C7IA 3NHNA 1AOUF 3HHMB 2JYQA 1BKLA 2FO0A 2EKXA 3M7FA 3VS5A 1JYUA 4K45A 4NWGA 1AB2A 3N84A 5J3XA 3VS1A 2DVJA 3UF4A 1B47A 4X6SA 4H34A 1OO4A 1F2FA 2BBUA 2CBLA 3VS3A 1AYCA 1O4MA 1M61A 3TKZA 4GPLB 1AD5A 2MRJA 2EOBA 5AULA 1O46A 1KA6A 3S8LA 5DC4A 1R1PA 5EHPA 2EYVA 1RJAA 4DGXA 2SRCA 1HCTB 1KA7A 2RSYA 1QCFA 1A08A 1BHHA 1YVHA 1Z3KA 3BKBA 1O4DA 2C0OA 2DX0A
chains in the Genus database with same CATH topology
1O49A 2PLDA 1ZFPE 1RQQC 3T04A 3UYOA 1O4CA 4OHIA 2RMXA 1AYDA 2K79B 1IS0A 1IJRA 4M4ZA 3HCKA 1O44A 4ROJA 2CS0A 1NRVA 1LUMA 4JEGA 3S9KA 2HMHA 2AOAA 1FU6A 3VS4A 3OB1B 3N7YA 5CDWA 1BHFA 3EAZA 2GE9A 1O4IA 2B3OA 2HDVA 1LKLA 2MRKA 1F1WA 1FMKA 4F59A 4FBNA 3GXXA 1CJ1A 5IBMA 1SHAA 2PNBA 4H1OA 2FCIA 3PQZA 4A4CA 3VGOA 2H5KA 2MK2A 1R1SA 1A1CA 2MQIA 4NWFA 4FL2A 1BMBA 2DM0A 4F5AA 2KK6A 3PSJA 2EU0A 2PTKA 1O4NA 4U1PA 3CWGA 1LKKA 2EO3A 3GQIB 1AOTF 1FBVA 2YU7A 3S8NA 1O42A 5DC9A 2Y1MA 2EYZA 2Y1NA 1PICA 1LCJA 1O45A 2EL8A 1OO3A 1P13A 2HDXA 3KFJA 2AUGA 1O4EA 3PJPA 2LNWA 3BUXB 3WA4A 1D4WA 2CR4A 1QADA 4FL3A 1O4LA 1O4AA 3VS7A 1CSZA 4OHHA 2AOBA 4K44A 4WWQA 1QG1E 2K7AB 1BF5A 3EACA 1LCKA 1A07A 2GSBA 1GRIA 2YSXA 1JYQA 2C0TA 4LUDA 1NZLA 1A81A 1O4OA 2CRHA 1SPSA 4K2RA 3VROA 1CWDL 2CI8A 2LQNA 2IUIA 1CWEA 1BFIA 1A1BA 1BKMA 3PSKA 3K2MA 2C9WA 1AYBA 4F5BA 1H9OA 1JU5A 2L4KA 4JGHA 3VS6A 4OHLA 5EELA 3CBLA 2PNAA 3MXYA 3VS2A 1JYRA 4EY0A 3VRRA 4A4BA 3OB2B 5HKYA 2CIAA 5EEQA 3IMDA 1FBZA 3OVEA 1TCEA 4DGPA 3BUOB 3VS0A 2ETZA 1WQUA 1RPYA 3IMJA 1X6CA 1BFJA 4QSYA 5DF6A 4L1BB 1JWOA 2IUHA 1HCSB 2DLYA 1UUSA 3US4A 1YVLA 1O4HA 2XP1A 3N8MA 2DLZA 2HUWA 2PLEA 1UURA 2QMSA 1OPKA 4OHDA 4XZ0A 1O4FA 1A1EA 1BG1A 1XA6A 1CSYA 1FYRA 1AYAA 1O4QA 3PS5A 2SHPA 1LUKA 1Y1UA 4U17A 5EHRA 4OHEA 3BUMB 1O48A 4XZ1A 2VIFA 2RVFA 2ECDA 4GWFA 3VRQA 1TZEE 2MC1A 4LUEA 3IN7A 4P9VA 2H8HA 2ABLA 4E68A 3ZNIA 5I6VA 1MW4A 1X27A 1A1AA 5HKWA 2KNOA 5AXIA 3PLFB 3OP0A 2C0IA 1G83A 3CD3A 2L6KA 5IBSA 3VRYA 1BHHB 2DCRA 1O47A 2LCTA 1D1ZA 3OV1A 1X0NA 3HIZB 1D4TA 2L3TA 4E93A 3CXLA 2OZOA 5KAZA 3QWXX 1O4GA 4GL9E 3VRNA 1R1QA 3PFVA 3QWYA 3S8OA 1O4PA 2LNXA 5BO4A 3IN8A 1O41A 1A09A 3MAZA 2LQWA 1BLKA 3VRPA 1BM2A 5GJIA 2IUGA 1K9AA 1M27A 1KSWA 5EG3B 1FU5A 1SPRA 1LUNA 2CI9A 1FHSA 5HKZA 2EO6A 3TL0A 1GHUA 1O4RA 5DC0B 1SHBA 1OPLA 1O4KA 2OQ1A 1O4BA 2HCKA 2RORA 3VRZA 4JE4A 2Y3AB 1LUIA 4P9ZA 3GXWA 1NZVA 4D8KA 1KC2A 2EYYA 2IZVA 1O4JA 4K11A 4TZIA 1SHDA 1O43A 3BUWB 2H46E 3BUNB 3MXCA 1MILA 1SKJA 1BLJA 1I3ZA 5D0JA 4EIHA 5GJHA 1Y57A 3C7IA 3NHNA 1AOUF 3HHMB 2JYQA 1BKLA 2FO0A 2EKXA 3M7FA 3VS5A 1JYUA 4K45A 4NWGA 1AB2A 3N84A 5J3XA 3VS1A 2DVJA 3UF4A 1B47A 4X6SA 4H34A 1OO4A 1F2FA 2BBUA 2CBLA 3VS3A 1AYCA 1O4MA 1M61A 3TKZA 4GPLB 1AD5A 2MRJA 2EOBA 5AULA 1O46A 1KA6A 3S8LA 5DC4A 1R1PA 5EHPA 2EYVA 1RJAA 4DGXA 2SRCA 1HCTB 1KA7A 2RSYA 1QCFA 1A08A 1BHHA 1YVHA 1Z3KA 3BKBA 1O4DA 2C0OA 2DX0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O49 A;  2PLD A;  1ZFP E;  1RQQ C;  3T04 A;  3UYO A;  1O4C A;  4OHI A;  2RMX A;  1AYD A;  2K79 B;  1IS0 A;  1IJR A;  4M4Z A;  3HCK A;  1O44 A;  4ROJ A;  2CS0 A;  1NRV A;  1LUM A;  4JEG A;  3S9K A;  2HMH A;  2AOA A;  1FU6 A;  3VS4 A;  3OB1 B;  3N7Y A;  5CDW A;  1BHF A;  3EAZ A;  2GE9 A;  1O4I A;  2B3O A;  2HDV A;  1LKL A;  2MRK A;  1F1W A;  1FMK A;  4F59 A;  4FBN A;  3GXX A;  1CJ1 A;  5IBM A;  1SHA A;  2PNB A;  4H1O A;  2FCI A;  3PQZ A;  4A4C A;  3VGO A;  2H5K A;  2MK2 A;  1R1S A;  1A1C A;  2MQI A;  4NWF A;  4FL2 A;  1BMB A;  2DM0 A;  4F5A A;  2KK6 A;  3PSJ A;  2EU0 A;  2PTK A;  1O4N A;  4U1P A;  3CWG A;  1LKK A;  2EO3 A;  3GQI B;  1AOT F;  1FBV A;  2YU7 A;  3S8N A;  1O42 A;  5DC9 A;  2Y1M A;  2EYZ A;  2Y1N A;  1PIC A;  1LCJ A;  1O45 A;  2EL8 A;  1OO3 A;  1P13 A;  2HDX A;  3KFJ A;  2AUG A;  1O4E A;  3PJP A;  2LNW A;  3BUX B;  3WA4 A;  1D4W A;  2CR4 A;  1QAD A;  4FL3 A;  1O4L A;  1O4A A;  3VS7 A;  1CSZ A;  4OHH A;  2AOB A;  4K44 A;  4WWQ A;  1QG1 E;  2K7A B;  1BF5 A;  3EAC A;  1LCK A;  1A07 A;  2GSB A;  1GRI A;  2YSX A;  1JYQ A;  2C0T A;  4LUD A;  1NZL A;  1A81 A;  1O4O A;  2CRH A;  1SPS A;  4K2R A;  3VRO A;  1CWD L;  2CI8 A;  2LQN A;  2IUI A;  1CWE A;  1BFI A;  1A1B A;  1BKM A;  3PSK A;  3K2M A;  2C9W A;  1AYB A;  4F5B A;  1H9O A;  1JU5 A;  2L4K A;  4JGH A;  3VS6 A;  4OHL A;  5EEL A;  3CBL A;  2PNA A;  3MXY A;  3VS2 A;  1JYR A;  4EY0 A;  3VRR A;  4A4B A;  3OB2 B;  5HKY A;  2CIA A;  5EEQ A;  3IMD A;  1FBZ A;  3OVE A;  1TCE A;  4DGP A;  3BUO B;  3VS0 A;  2ETZ A;  1WQU A;  1RPY A;  3IMJ A;  1X6C A;  1BFJ A;  4QSY A;  5DF6 A;  4L1B B;  1JWO A;  2IUH A;  1HCS B;  2DLY A;  1UUS A;  3US4 A;  1YVL A;  1O4H A;  2XP1 A;  3N8M A;  2DLZ A;  2HUW A;  2PLE A;  1UUR A;  2QMS A;  1OPK A;  4OHD A;  4XZ0 A;  1O4F A;  1A1E A;  1BG1 A;  1XA6 A;  1CSY A;  1FYR A;  1AYA A;  1O4Q A;  3PS5 A;  2SHP A;  1LUK A;  1Y1U A;  4U17 A;  5EHR A;  4OHE A;  3BUM B;  1O48 A;  4XZ1 A;  2VIF A;  2RVF A;  2ECD A;  4GWF A;  3VRQ A;  1TZE E;  2MC1 A;  4LUE A;  3IN7 A;  4P9V A;  2H8H A;  2ABL A;  4E68 A;  3ZNI A;  5I6V A;  1MW4 A;  1X27 A;  1A1A A;  5HKW A;  2KNO A;  5AXI A;  3PLF B;  3OP0 A;  2C0I A;  1G83 A;  3CD3 A;  2L6K A;  5IBS A;  3VRY A;  1BHH B;  2DCR A;  1O47 A;  2LCT A;  1D1Z A;  3OV1 A;  1X0N A;  3HIZ B;  1D4T A;  2L3T A;  4E93 A;  3CXL A;  2OZO A;  5KAZ A;  3QWX X;  1O4G A;  4GL9 E;  3VRN A;  1R1Q A;  3PFV A;  3QWY A;  3S8O A;  1O4P A;  2LNX A;  5BO4 A;  3IN8 A;  1O41 A;  1A09 A;  3MAZ A;  2LQW A;  1BLK A;  3VRP A;  1BM2 A;  5GJI A;  2IUG A;  1K9A A;  1M27 A;  1KSW A;  5EG3 B;  1FU5 A;  1SPR A;  1LUN A;  2CI9 A;  1FHS A;  5HKZ A;  2EO6 A;  3TL0 A;  1GHU A;  1O4R A;  5DC0 B;  1SHB A;  1OPL A;  1O4K A;  2OQ1 A;  1O4B A;  2HCK A;  2ROR A;  3VRZ A;  4JE4 A;  2Y3A B;  1LUI A;  4P9Z A;  3GXW A;  1NZV A;  4D8K A;  1KC2 A;  2EYY A;  2IZV A;  1O4J A;  4K11 A;  4TZI A;  1SHD A;  1O43 A;  3BUW B;  2H46 E;  3BUN B;  3MXC A;  1MIL A;  1SKJ A;  1BLJ A;  1I3Z A;  5D0J A;  4EIH A;  5GJH A;  1Y57 A;  3C7I A;  3NHN A;  1AOU F;  3HHM B;  2JYQ A;  1BKL A;  2FO0 A;  2EKX A;  3M7F A;  3VS5 A;  1JYU A;  4K45 A;  4NWG A;  1AB2 A;  3N84 A;  5J3X A;  3VS1 A;  2DVJ A;  3UF4 A;  1B47 A;  4X6S A;  4H34 A;  1OO4 A;  1F2F A;  2BBU A;  2CBL A;  3VS3 A;  1AYC A;  1O4M A;  1M61 A;  3TKZ A;  4GPL B;  1AD5 A;  2MRJ A;  2EOB A;  5AUL A;  1O46 A;  1KA6 A;  3S8L A;  5DC4 A;  1R1P A;  5EHP A;  2EYV A;  1RJA A;  4DGX A;  2SRC A;  1HCT B;  1KA7 A;  2RSY A;  1QCF A;  1A08 A;  1BHH A;  1YVH A;  1Z3K A;  3BKB A;  1O4D A;  2C0O A;  2DX0 A; 
#chains in the Genus database with same CATH topology
 1O49 A;  2PLD A;  1ZFP E;  1RQQ C;  3T04 A;  3UYO A;  1O4C A;  4OHI A;  2RMX A;  1AYD A;  2K79 B;  1IS0 A;  1IJR A;  4M4Z A;  3HCK A;  1O44 A;  4ROJ A;  2CS0 A;  1NRV A;  1LUM A;  4JEG A;  3S9K A;  2HMH A;  2AOA A;  1FU6 A;  3VS4 A;  3OB1 B;  3N7Y A;  5CDW A;  1BHF A;  3EAZ A;  2GE9 A;  1O4I A;  2B3O A;  2HDV A;  1LKL A;  2MRK A;  1F1W A;  1FMK A;  4F59 A;  4FBN A;  3GXX A;  1CJ1 A;  5IBM A;  3LYV A;  1SHA A;  2PNB A;  4H1O A;  2FCI A;  3PQZ A;  4A4C A;  3VGO A;  2H5K A;  2MK2 A;  1R1S A;  1A1C A;  2MQI A;  4NWF A;  4FL2 A;  1BMB A;  2DM0 A;  4F5A A;  2KK6 A;  3PSJ A;  2EU0 A;  2PTK A;  2LRA A;  1O4N A;  4U1P A;  3CWG A;  1LKK A;  2EO3 A;  3GQI B;  1AOT F;  1FBV A;  2YU7 A;  3S8N A;  1O42 A;  5DC9 A;  2Y1M A;  2EYZ A;  2Y1N A;  1PIC A;  1LCJ A;  1O45 A;  2EL8 A;  1OO3 A;  1P13 A;  2HDX A;  3KFJ A;  2AUG A;  1O4E A;  3PJP A;  2LNW A;  3BUX B;  3WA4 A;  1D4W A;  2CR4 A;  1QAD A;  4FL3 A;  1O4L A;  1O4A A;  3VS7 A;  1CSZ A;  4OHH A;  2AOB A;  4K44 A;  4WWQ A;  1QG1 E;  2K7A B;  1BF5 A;  3EAC A;  1LCK A;  1A07 A;  2GSB A;  1GRI A;  2YSX A;  1JYQ A;  2C0T A;  4LUD A;  1NZL A;  1A81 A;  1O4O A;  2CRH A;  1SPS A;  4K2R A;  3VRO A;  1CWD L;  2CI8 A;  2LQN A;  2IUI A;  1CWE A;  1BFI A;  1A1B A;  1BKM A;  3PSK A;  3K2M A;  2C9W A;  1AYB A;  4F5B A;  1H9O A;  1JU5 A;  2L4K A;  4JGH A;  3VS6 A;  4OHL A;  5EEL A;  3CBL A;  2PNA A;  3MXY A;  3VS2 A;  1JYR A;  4EY0 A;  3VRR A;  4A4B A;  3OB2 B;  5HKY A;  2CIA A;  5EEQ A;  3IMD A;  1FBZ A;  3OVE A;  1TCE A;  4DGP A;  3BUO B;  3VS0 A;  2ETZ A;  1WQU A;  1RPY A;  3IMJ A;  1X6C A;  1BFJ A;  4QSY A;  5DF6 A;  4L1B B;  1JWO A;  2IUH A;  1HCS B;  2DLY A;  1UUS A;  3US4 A;  1YVL A;  1O4H A;  2XP1 A;  3N8M A;  2DLZ A;  2HUW A;  2PLE A;  1UUR A;  2QMS A;  1OPK A;  4OHD A;  4XZ0 A;  1O4F A;  1A1E A;  1BG1 A;  1XA6 A;  1CSY A;  1FYR A;  1AYA A;  1O4Q A;  3PS5 A;  2SHP A;  1LUK A;  1Y1U A;  4U17 A;  5EHR A;  4OHE A;  3BUM B;  1O48 A;  4XZ1 A;  2VIF A;  2RVF A;  2ECD A;  4GWF A;  3VRQ A;  1TZE E;  2MC1 A;  4LUE A;  3IN7 A;  4P9V A;  2H8H A;  2ABL A;  4E68 A;  3ZNI A;  5I6V A;  1MW4 A;  1X27 A;  1A1A A;  5HKW A;  2KNO A;  5AXI A;  3PLF B;  3OP0 A;  2C0I A;  1G83 A;  3CD3 A;  2L6K A;  5IBS A;  3VRY A;  1BHH B;  2DCR A;  1O47 A;  2LCT A;  1D1Z A;  3OV1 A;  1X0N A;  3HIZ B;  1D4T A;  2L3T A;  4E93 A;  3CXL A;  2OZO A;  5KAZ A;  3QWX X;  1O4G A;  4GL9 E;  3VRN A;  1R1Q A;  3PFV A;  3QWY A;  3S8O A;  1O4P A;  2LNX A;  5BO4 A;  3IN8 A;  1O41 A;  1A09 A;  3MAZ A;  2LQW A;  1BLK A;  3K2T A;  3VRP A;  1BM2 A;  5GJI A;  2KGY A;  2IUG A;  1K9A A;  1M27 A;  1KSW A;  5EG3 B;  1FU5 A;  1SPR A;  1LUN A;  2CI9 A;  1FHS A;  5HKZ A;  2EO6 A;  3TL0 A;  1GHU A;  1O4R A;  5DC0 B;  1SHB A;  1OPL A;  1O4K A;  2OQ1 A;  1O4B A;  2HCK A;  2ROR A;  3VRZ A;  4JE4 A;  2Y3A B;  1LUI A;  4P9Z A;  3GXW A;  1NZV A;  4D8K A;  1KC2 A;  2EYY A;  2IZV A;  1O4J A;  4K11 A;  4TZI A;  1SHD A;  1O43 A;  3BUW B;  2H46 E;  3BUN B;  3MXC A;  1MIL A;  1SKJ A;  1BLJ A;  1I3Z A;  5D0J A;  4EIH A;  5GJH A;  1Y57 A;  3C7I A;  3NHN A;  1AOU F;  3HHM B;  2JYQ A;  1BKL A;  2FO0 A;  2EKX A;  3M7F A;  3VS5 A;  1JYU A;  4K45 A;  4NWG A;  1AB2 A;  3N84 A;  5J3X A;  3VS1 A;  2DVJ A;  3UF4 A;  1B47 A;  4X6S A;  4H34 A;  1OO4 A;  1F2F A;  2BBU A;  2CBL A;  3VS3 A;  1AYC A;  1O4M A;  1M61 A;  3TKZ A;  4GPL B;  1AD5 A;  2MRJ A;  2EOB A;  5AUL A;  1O46 A;  1KA6 A;  3S8L A;  5DC4 A;  1R1P A;  5EHP A;  2EYV A;  1RJA A;  4DGX A;  2SRC A;  1HCT B;  1KA7 A;  2RSY A;  1QCF A;  1A08 A;  1BHH A;  1YVH A;  1Z3K A;  3BKB A;  1O4D A;  2C0O A;  2DX0 A; 
#chains in the Genus database with same CATH homology
 1O49 A;  2PLD A;  1ZFP E;  1RQQ C;  3T04 A;  3UYO A;  1O4C A;  4OHI A;  2RMX A;  1AYD A;  2K79 B;  1IS0 A;  1IJR A;  4M4Z A;  3HCK A;  1O44 A;  4ROJ A;  2CS0 A;  1NRV A;  1LUM A;  4JEG A;  3S9K A;  2HMH A;  2AOA A;  1FU6 A;  3VS4 A;  3OB1 B;  3N7Y A;  5CDW A;  1BHF A;  3EAZ A;  2GE9 A;  1O4I A;  2B3O A;  2HDV A;  1LKL A;  2MRK A;  1F1W A;  1FMK A;  4F59 A;  4FBN A;  3GXX A;  1CJ1 A;  5IBM A;  1SHA A;  2PNB A;  4H1O A;  2FCI A;  3PQZ A;  4A4C A;  3VGO A;  2H5K A;  2MK2 A;  1R1S A;  1A1C A;  2MQI A;  4NWF A;  4FL2 A;  1BMB A;  2DM0 A;  4F5A A;  2KK6 A;  3PSJ A;  2EU0 A;  2PTK A;  1O4N A;  4U1P A;  3CWG A;  1LKK A;  2EO3 A;  3GQI B;  1AOT F;  1FBV A;  2YU7 A;  3S8N A;  1O42 A;  5DC9 A;  2Y1M A;  2EYZ A;  2Y1N A;  1PIC A;  1LCJ A;  1O45 A;  2EL8 A;  1OO3 A;  1P13 A;  2HDX A;  3KFJ A;  2AUG A;  1O4E A;  3PJP A;  2LNW A;  3BUX B;  3WA4 A;  1D4W A;  2CR4 A;  1QAD A;  4FL3 A;  1O4L A;  1O4A A;  3VS7 A;  1CSZ A;  4OHH A;  2AOB A;  4K44 A;  4WWQ A;  1QG1 E;  2K7A B;  1BF5 A;  3EAC A;  1LCK A;  1A07 A;  2GSB A;  1GRI A;  2YSX A;  1JYQ A;  2C0T A;  4LUD A;  1NZL A;  1A81 A;  1O4O A;  2CRH A;  1SPS A;  4K2R A;  3VRO A;  1CWD L;  2CI8 A;  2LQN A;  2IUI A;  1CWE A;  1BFI A;  1A1B A;  1BKM A;  3PSK A;  3K2M A;  2C9W A;  1AYB A;  4F5B A;  1H9O A;  1JU5 A;  2L4K A;  4JGH A;  3VS6 A;  4OHL A;  5EEL A;  3CBL A;  2PNA A;  3MXY A;  3VS2 A;  1JYR A;  4EY0 A;  3VRR A;  4A4B A;  3OB2 B;  5HKY A;  2CIA A;  5EEQ A;  3IMD A;  1FBZ A;  3OVE A;  1TCE A;  4DGP A;  3BUO B;  3VS0 A;  2ETZ A;  1WQU A;  1RPY A;  3IMJ A;  1X6C A;  1BFJ A;  4QSY A;  5DF6 A;  4L1B B;  1JWO A;  2IUH A;  1HCS B;  2DLY A;  1UUS A;  3US4 A;  1YVL A;  1O4H A;  2XP1 A;  3N8M A;  2DLZ A;  2HUW A;  2PLE A;  1UUR A;  2QMS A;  1OPK A;  4OHD A;  4XZ0 A;  1O4F A;  1A1E A;  1BG1 A;  1XA6 A;  1CSY A;  1FYR A;  1AYA A;  1O4Q A;  3PS5 A;  2SHP A;  1LUK A;  1Y1U A;  4U17 A;  5EHR A;  4OHE A;  3BUM B;  1O48 A;  4XZ1 A;  2VIF A;  2RVF A;  2ECD A;  4GWF A;  3VRQ A;  1TZE E;  2MC1 A;  4LUE A;  3IN7 A;  4P9V A;  2H8H A;  2ABL A;  4E68 A;  3ZNI A;  5I6V A;  1MW4 A;  1X27 A;  1A1A A;  5HKW A;  2KNO A;  5AXI A;  3PLF B;  3OP0 A;  2C0I A;  1G83 A;  3CD3 A;  2L6K A;  5IBS A;  3VRY A;  1BHH B;  2DCR A;  1O47 A;  2LCT A;  1D1Z A;  3OV1 A;  1X0N A;  3HIZ B;  1D4T A;  2L3T A;  4E93 A;  3CXL A;  2OZO A;  5KAZ A;  3QWX X;  1O4G A;  4GL9 E;  3VRN A;  1R1Q A;  3PFV A;  3QWY A;  3S8O A;  1O4P A;  2LNX A;  5BO4 A;  3IN8 A;  1O41 A;  1A09 A;  3MAZ A;  2LQW A;  1BLK A;  3VRP A;  1BM2 A;  5GJI A;  2IUG A;  1K9A A;  1M27 A;  1KSW A;  5EG3 B;  1FU5 A;  1SPR A;  1LUN A;  2CI9 A;  1FHS A;  5HKZ A;  2EO6 A;  3TL0 A;  1GHU A;  1O4R A;  5DC0 B;  1SHB A;  1OPL A;  1O4K A;  2OQ1 A;  1O4B A;  2HCK A;  2ROR A;  3VRZ A;  4JE4 A;  2Y3A B;  1LUI A;  4P9Z A;  3GXW A;  1NZV A;  4D8K A;  1KC2 A;  2EYY A;  2IZV A;  1O4J A;  4K11 A;  4TZI A;  1SHD A;  1O43 A;  3BUW B;  2H46 E;  3BUN B;  3MXC A;  1MIL A;  1SKJ A;  1BLJ A;  1I3Z A;  5D0J A;  4EIH A;  5GJH A;  1Y57 A;  3C7I A;  3NHN A;  1AOU F;  3HHM B;  2JYQ A;  1BKL A;  2FO0 A;  2EKX A;  3M7F A;  3VS5 A;  1JYU A;  4K45 A;  4NWG A;  1AB2 A;  3N84 A;  5J3X A;  3VS1 A;  2DVJ A;  3UF4 A;  1B47 A;  4X6S A;  4H34 A;  1OO4 A;  1F2F A;  2BBU A;  2CBL A;  3VS3 A;  1AYC A;  1O4M A;  1M61 A;  3TKZ A;  4GPL B;  1AD5 A;  2MRJ A;  2EOB A;  5AUL A;  1O46 A;  1KA6 A;  3S8L A;  5DC4 A;  1R1P A;  5EHP A;  2EYV A;  1RJA A;  4DGX A;  2SRC A;  1HCT B;  1KA7 A;  2RSY A;  1QCF A;  1A08 A;  1BHH A;  1YVH A;  1Z3K A;  3BKB A;  1O4D A;  2C0O A;  2DX0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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