3US4A

Crystal structure of a sh2 domain of a megakaryocyte-associated tyrosine kinase (matk) from homo sapiens at 1.50 a resolution
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
97
structure length
97
Chain Sequence
LSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a SH2 domain of a megakaryocyte-associated tyrosine kinase (MATK) from Homo sapiens at 1.50 A resolution
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Megakaryocyte-associated tyrosine-protein kinase
total genus 21
structure length 97
sequence length 97
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3us4A00
1HCTB 2Y3AB 4XZ1A 3KFJA 5HKWA 4D8KA 1SPSA 1IS0A 4FBNA 4P9VA 5D0JA 4DGXA 1BMBA 3HIZB 2OQ1A 5BO4A 1O49A 2CR4A 1YVLA 4X6SA 1JYRA 2IUHA 1FYRA 5EEQA 1O43A 4H1OA 2LQWA 2C0IA 1Y1UA 2C9WA 5IBMA 1FMKA 1R1PA 1SHDA 2GE9A 2KNOA 1OO4A 1A09A 1SPRA 2HMHA 1O4NA 3WA4A 1AYCA 4OHDA 1FHSA 2EU0A 3VRNA 1F1WA 3CD3A 3IMJA 3VS6A 2OZOA 1X27A 4GL9E 2IUIA 4OHHA 1M61A 3OB1B 2PNAA 1QCFA 1O4BA 5GJIA 1X6CA 5EHPA 1O4MA 4NWFA 1O47A 2CRHA 1RQQC 1YVHA 1BHHA 2EYYA 2AOBA 1O4AA 1AD5A 3VS5A 3PQZA 3VRQA 2IUGA 3BUMB 1WQUA 1UURA 2HDVA 3BUXB 1LUNA 1JYQA 1OPLA 4EY0A 1HCSB 2CBLA 2L3TA 3VRRA 1F2FA 3S8OA 3PLFB 4U1PA 5KAZA 1O46A 3VRZA 2EYVA 2PLDA 1OPKA 2SRCA 3BUOB 5GJHA 5DC9A 1FU6A 3PSKA 1O4OA 1O4IA 1JU5A 4XZ0A 4GPLB 2ECDA 3BUWB 1D4TA 1O4FA 1FU5A 2C0TA 2MQIA 1BKMA 2K79B 1O4GA 3N8MA 3S8NA 1O4CA 1LUIA 1A1EA 4OHIA 4L1BB 2PLEA 1JWOA 3VRYA 4QSYA 5CDWA 2RSYA 1IJRA 3GXXA 1GHUA 1BLJA 1O4JA 4A4CA 5AULA 1MW4A 3S8LA 2HDXA 3OB2B 1SHBA 4GWFA 4F5AA 1H9OA 1A1CA 1LUKA 4TZIA 1TCEA 1G83A 3PSJA 2KK6A 3GXWA 1SHAA 4A4BA 5J3XA 2YU7A 2FCIA 1GRIA 2EKXA 3OVEA 1NZVA 3VGOA 1JYUA 3BKBA 1CWDL 1O41A 2CI8A 2GSBA 1AYDA 1BM2A 2SHPA 2VIFA 1R1QA 4OHLA 4H34A 1CSYA 2EYZA 4ROJA 1O4RA 4JE4A 2LNWA 1TZEE 3CWGA 5HKZA 1O4LA 3IN7A 1A81A 4K44A 1A1AA 1A1BA 3VROA 3VRPA 2CIAA 3PS5A 3VS2A 1A07A 1BFJA 1LKKA 1BKLA 3TKZA 1O4EA 4JEGA 3M7FA 2LQNA 4FL3A 3UF4A 1LCKA 2H46E 3QWXX 2RORA 2DVJA 3MXYA 3VS7A 1BFIA 1M27A 5DC0B 1BHHB 3VS1A 1QADA 1ZFPE 3ZNIA 2EOBA 4LUDA 3GQIB 2FO0A 2CS0A 2HUWA 2HCKA 2PNBA 4EIHA 3IN8A 3OP0A 1Z3KA 3PJPA 2DCRA 2RMXA 3K2MA 2EO3A 1CWEA 1KA7A 1O4QA 3MAZA 1RJAA 2DX0A 5AXIA 1BG1A 2MC1A 2MRJA 3CBLA 1KA6A 5EHRA 4K11A 3OV1A 4NWGA 2AOAA 1OO3A 4LUEA 3N7YA 3S9KA 2MK2A 1P13A 5DF6A 5IBSA 3QWYA 2YSXA 1CJ1A 3VS0A 1AOTF 3UYOA 1A08A 1CSZA 3EAZA 1R1SA 3US4A 4F59A 1FBVA 2Y1NA 3BUNB 1LUMA 1B47A 1AB2A 2BBUA 4E68A 4JGHA 2K7AB 1O4KA 2L6KA 2ETZA 2MRKA 1AOUF 4M4ZA 2LCTA 1LCJA 1K9AA 4P9ZA 3IMDA 3HHMB 3N84A 1O48A 1O4PA 2DLYA 4E93A 1RPYA 1O4HA 4K45A 4FL2A 5EELA 1MILA 1I3ZA 3T04A 2C0OA 2EO6A 2DM0A 3EACA 1BF5A 2B3OA 3NHNA 2H8HA 1O45A 4U17A 3MXCA 4DGPA 1XA6A 2AUGA 5DC4A 2RVFA 1SKJA 4F5BA 1BHFA 1AYBA 1O42A 2PTKA 4WWQA 3TL0A 1KC2A 1UUSA 1X0NA 2H5KA 1NZLA 5EG3B 4OHEA 5HKYA 3PFVA 1O44A 2JYQA 2XP1A 2LNXA 2ABLA 5I6VA 1Y57A 4K2RA 2IZVA 2Y1MA 3CXLA 1KSWA 2CI9A 1D4WA 2EL8A 1D1ZA 3VS3A 1AYAA 1PICA 3HCKA 1O4DA 3C7IA 1BLKA 1NRVA 1QG1E 1LKLA 3VS4A 2QMSA 1FBZA 2L4KA 2DLZA
chains in the Genus database with same CATH superfamily
1HCTB 2Y3AB 4XZ1A 3KFJA 5HKWA 4D8KA 1SPSA 1IS0A 4FBNA 4P9VA 5D0JA 4DGXA 1BMBA 3HIZB 2OQ1A 5BO4A 1O49A 2CR4A 1YVLA 4X6SA 1JYRA 2IUHA 1FYRA 5EEQA 1O43A 4H1OA 2LQWA 2C0IA 1Y1UA 2C9WA 5IBMA 1FMKA 1R1PA 1SHDA 2GE9A 2KNOA 1OO4A 1A09A 1SPRA 2HMHA 1O4NA 3WA4A 1AYCA 4OHDA 1FHSA 2EU0A 3VRNA 1F1WA 3CD3A 3IMJA 3VS6A 2OZOA 1X27A 4GL9E 2IUIA 4OHHA 1M61A 3OB1B 2PNAA 1QCFA 1O4BA 5GJIA 1X6CA 5EHPA 3LYVA 1O4MA 4NWFA 1O47A 2CRHA 1RQQC 1YVHA 1BHHA 2EYYA 2LRAA 2AOBA 1O4AA 1AD5A 3VS5A 3PQZA 3VRQA 2IUGA 3BUMB 1WQUA 1UURA 2HDVA 3BUXB 1LUNA 1JYQA 1OPLA 4EY0A 1HCSB 2CBLA 2L3TA 3VRRA 1F2FA 3S8OA 3PLFB 4U1PA 5KAZA 1O46A 3VRZA 2EYVA 2PLDA 1OPKA 2SRCA 3BUOB 5GJHA 5DC9A 1FU6A 3PSKA 1O4OA 1O4IA 1JU5A 4XZ0A 4GPLB 2ECDA 3BUWB 1D4TA 1O4FA 1FU5A 2C0TA 2MQIA 1BKMA 2K79B 1O4GA 3N8MA 3S8NA 1O4CA 1LUIA 1A1EA 4OHIA 4L1BB 2PLEA 1JWOA 3VRYA 4QSYA 5CDWA 2RSYA 1IJRA 3GXXA 1GHUA 1BLJA 1O4JA 4A4CA 5AULA 1MW4A 3S8LA 2HDXA 3OB2B 1SHBA 4GWFA 4F5AA 1H9OA 1A1CA 1LUKA 4TZIA 1TCEA 1G83A 3PSJA 2KK6A 3GXWA 1SHAA 4A4BA 5J3XA 2YU7A 2FCIA 1GRIA 2EKXA 3OVEA 1NZVA 3VGOA 1JYUA 3K2TA 3BKBA 1CWDL 1O41A 2CI8A 2GSBA 1AYDA 1BM2A 2SHPA 2VIFA 1R1QA 4OHLA 4H34A 1CSYA 2EYZA 4ROJA 1O4RA 4JE4A 2LNWA 1TZEE 3CWGA 5HKZA 1O4LA 3IN7A 1A81A 4K44A 1A1AA 1A1BA 3VROA 3VRPA 2CIAA 3PS5A 3VS2A 1A07A 1BFJA 1LKKA 1BKLA 3TKZA 1O4EA 4JEGA 3M7FA 2LQNA 4FL3A 3UF4A 1LCKA 2H46E 3QWXX 2RORA 2DVJA 3MXYA 3VS7A 1BFIA 1M27A 5DC0B 1BHHB 3VS1A 1QADA 1ZFPE 3ZNIA 2EOBA 4LUDA 3GQIB 2FO0A 2CS0A 2HUWA 2HCKA 2PNBA 4EIHA 3IN8A 3OP0A 1Z3KA 3PJPA 2DCRA 2RMXA 3K2MA 2EO3A 1CWEA 1KA7A 1O4QA 3MAZA 1RJAA 2DX0A 5AXIA 1BG1A 2MC1A 2MRJA 3CBLA 1KA6A 2KGYA 5EHRA 4K11A 3OV1A 4NWGA 2AOAA 1OO3A 4LUEA 3N7YA 3S9KA 2MK2A 1P13A 5DF6A 5IBSA 3QWYA 2YSXA 1CJ1A 3VS0A 1AOTF 3UYOA 1A08A 1CSZA 3EAZA 1R1SA 3US4A 4F59A 1FBVA 2Y1NA 3BUNB 1LUMA 1B47A 1AB2A 2BBUA 4E68A 4JGHA 2K7AB 1O4KA 2L6KA 2ETZA 2MRKA 1AOUF 4M4ZA 2LCTA 1LCJA 1K9AA 4P9ZA 3IMDA 3HHMB 3N84A 1O48A 1O4PA 2DLYA 4E93A 1RPYA 1O4HA 4K45A 4FL2A 5EELA 1MILA 1I3ZA 3T04A 2C0OA 2EO6A 2DM0A 3EACA 1BF5A 2B3OA 3NHNA 2H8HA 1O45A 4U17A 3MXCA 4DGPA 1XA6A 2AUGA 5DC4A 2RVFA 1SKJA 4F5BA 1BHFA 1AYBA 1O42A 2PTKA 4WWQA 3TL0A 1KC2A 1UUSA 1X0NA 2H5KA 1NZLA 5EG3B 4OHEA 5HKYA 3PFVA 1O44A 2JYQA 2XP1A 2LNXA 2ABLA 5I6VA 1Y57A 4K2RA 2IZVA 2Y1MA 3CXLA 1KSWA 2CI9A 1D4WA 2EL8A 1D1ZA 3VS3A 1AYAA 1PICA 3HCKA 1O4DA 3C7IA 1BLKA 1NRVA 1QG1E 1LKLA 3VS4A 2QMSA 1FBZA 2L4KA 2DLZA
chains in the Genus database with same CATH topology
1HCTB 2Y3AB 4XZ1A 3KFJA 5HKWA 4D8KA 1SPSA 1IS0A 4FBNA 4P9VA 5D0JA 4DGXA 1BMBA 3HIZB 2OQ1A 5BO4A 1O49A 2CR4A 1YVLA 4X6SA 1JYRA 2IUHA 1FYRA 5EEQA 1O43A 4H1OA 2LQWA 2C0IA 1Y1UA 2C9WA 5IBMA 1FMKA 1R1PA 1SHDA 2GE9A 2KNOA 1OO4A 1A09A 1SPRA 2HMHA 1O4NA 3WA4A 1AYCA 4OHDA 1FHSA 2EU0A 3VRNA 1F1WA 3CD3A 3IMJA 3VS6A 2OZOA 1X27A 4GL9E 2IUIA 4OHHA 1M61A 3OB1B 2PNAA 1QCFA 1O4BA 5GJIA 1X6CA 5EHPA 1O4MA 4NWFA 1O47A 2CRHA 1RQQC 1YVHA 1BHHA 2EYYA 2AOBA 1O4AA 1AD5A 3VS5A 3PQZA 3VRQA 2IUGA 3BUMB 1WQUA 1UURA 2HDVA 3BUXB 1LUNA 1JYQA 1OPLA 4EY0A 1HCSB 2CBLA 2L3TA 3VRRA 1F2FA 3S8OA 3PLFB 4U1PA 5KAZA 1O46A 3VRZA 2EYVA 2PLDA 1OPKA 2SRCA 3BUOB 5GJHA 5DC9A 1FU6A 3PSKA 1O4OA 1O4IA 1JU5A 4XZ0A 4GPLB 2ECDA 3BUWB 1D4TA 1O4FA 1FU5A 2C0TA 2MQIA 1BKMA 2K79B 1O4GA 3N8MA 3S8NA 1O4CA 1LUIA 1A1EA 4OHIA 4L1BB 2PLEA 1JWOA 3VRYA 4QSYA 5CDWA 2RSYA 1IJRA 3GXXA 1GHUA 1BLJA 1O4JA 4A4CA 5AULA 1MW4A 3S8LA 2HDXA 3OB2B 1SHBA 4GWFA 4F5AA 1H9OA 1A1CA 1LUKA 4TZIA 1TCEA 1G83A 3PSJA 2KK6A 3GXWA 1SHAA 4A4BA 5J3XA 2YU7A 2FCIA 1GRIA 2EKXA 3OVEA 1NZVA 3VGOA 1JYUA 3BKBA 1CWDL 1O41A 2CI8A 2GSBA 1AYDA 1BM2A 2SHPA 2VIFA 1R1QA 4OHLA 4H34A 1CSYA 2EYZA 4ROJA 1O4RA 4JE4A 2LNWA 1TZEE 3CWGA 5HKZA 1O4LA 3IN7A 1A81A 4K44A 1A1AA 1A1BA 3VROA 3VRPA 2CIAA 3PS5A 3VS2A 1A07A 1BFJA 1LKKA 1BKLA 3TKZA 1O4EA 4JEGA 3M7FA 2LQNA 4FL3A 3UF4A 1LCKA 2H46E 3QWXX 2RORA 2DVJA 3MXYA 3VS7A 1BFIA 1M27A 5DC0B 1BHHB 3VS1A 1QADA 1ZFPE 3ZNIA 2EOBA 4LUDA 3GQIB 2FO0A 2CS0A 2HUWA 2HCKA 2PNBA 4EIHA 3IN8A 3OP0A 1Z3KA 3PJPA 2DCRA 2RMXA 3K2MA 2EO3A 1CWEA 1KA7A 1O4QA 3MAZA 1RJAA 2DX0A 5AXIA 1BG1A 2MC1A 2MRJA 3CBLA 1KA6A 5EHRA 4K11A 3OV1A 4NWGA 2AOAA 1OO3A 4LUEA 3N7YA 3S9KA 2MK2A 1P13A 5DF6A 5IBSA 3QWYA 2YSXA 1CJ1A 3VS0A 1AOTF 3UYOA 1A08A 1CSZA 3EAZA 1R1SA 3US4A 4F59A 1FBVA 2Y1NA 3BUNB 1LUMA 1B47A 1AB2A 2BBUA 4E68A 4JGHA 2K7AB 1O4KA 2L6KA 2ETZA 2MRKA 1AOUF 4M4ZA 2LCTA 1LCJA 1K9AA 4P9ZA 3IMDA 3HHMB 3N84A 1O48A 1O4PA 2DLYA 4E93A 1RPYA 1O4HA 4K45A 4FL2A 5EELA 1MILA 1I3ZA 3T04A 2C0OA 2EO6A 2DM0A 3EACA 1BF5A 2B3OA 3NHNA 2H8HA 1O45A 4U17A 3MXCA 4DGPA 1XA6A 2AUGA 5DC4A 2RVFA 1SKJA 4F5BA 1BHFA 1AYBA 1O42A 2PTKA 4WWQA 3TL0A 1KC2A 1UUSA 1X0NA 2H5KA 1NZLA 5EG3B 4OHEA 5HKYA 3PFVA 1O44A 2JYQA 2XP1A 2LNXA 2ABLA 5I6VA 1Y57A 4K2RA 2IZVA 2Y1MA 3CXLA 1KSWA 2CI9A 1D4WA 2EL8A 1D1ZA 3VS3A 1AYAA 1PICA 3HCKA 1O4DA 3C7IA 1BLKA 1NRVA 1QG1E 1LKLA 3VS4A 2QMSA 1FBZA 2L4KA 2DLZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HCT B;  2Y3A B;  4XZ1 A;  3KFJ A;  5HKW A;  4D8K A;  1SPS A;  1IS0 A;  4FBN A;  4P9V A;  5D0J A;  4DGX A;  1BMB A;  3HIZ B;  2OQ1 A;  5BO4 A;  1O49 A;  2CR4 A;  1YVL A;  4X6S A;  1JYR A;  2IUH A;  1FYR A;  5EEQ A;  1O43 A;  4H1O A;  2LQW A;  2C0I A;  1Y1U A;  2C9W A;  5IBM A;  1FMK A;  1R1P A;  1SHD A;  2GE9 A;  2KNO A;  1OO4 A;  1A09 A;  1SPR A;  2HMH A;  1O4N A;  3WA4 A;  1AYC A;  4OHD A;  1FHS A;  2EU0 A;  3VRN A;  1F1W A;  3CD3 A;  3IMJ A;  3VS6 A;  2OZO A;  1X27 A;  4GL9 E;  2IUI A;  4OHH A;  1M61 A;  3OB1 B;  2PNA A;  1QCF A;  1O4B A;  5GJI A;  1X6C A;  5EHP A;  1O4M A;  4NWF A;  1O47 A;  2CRH A;  1RQQ C;  1YVH A;  1BHH A;  2EYY A;  2AOB A;  1O4A A;  1AD5 A;  3VS5 A;  3PQZ A;  3VRQ A;  2IUG A;  3BUM B;  1WQU A;  1UUR A;  2HDV A;  3BUX B;  1LUN A;  1JYQ A;  1OPL A;  4EY0 A;  1HCS B;  2CBL A;  2L3T A;  3VRR A;  1F2F A;  3S8O A;  3PLF B;  4U1P A;  5KAZ A;  1O46 A;  3VRZ A;  2EYV A;  2PLD A;  1OPK A;  2SRC A;  3BUO B;  5GJH A;  5DC9 A;  1FU6 A;  3PSK A;  1O4O A;  1O4I A;  1JU5 A;  4XZ0 A;  4GPL B;  2ECD A;  3BUW B;  1D4T A;  1O4F A;  1FU5 A;  2C0T A;  2MQI A;  1BKM A;  2K79 B;  1O4G A;  3N8M A;  3S8N A;  1O4C A;  1LUI A;  1A1E A;  4OHI A;  4L1B B;  2PLE A;  1JWO A;  3VRY A;  4QSY A;  5CDW A;  2RSY A;  1IJR A;  3GXX A;  1GHU A;  1BLJ A;  1O4J A;  4A4C A;  5AUL A;  1MW4 A;  3S8L A;  2HDX A;  3OB2 B;  1SHB A;  4GWF A;  4F5A A;  1H9O A;  1A1C A;  1LUK A;  4TZI A;  1TCE A;  1G83 A;  3PSJ A;  2KK6 A;  3GXW A;  1SHA A;  4A4B A;  5J3X A;  2YU7 A;  2FCI A;  1GRI A;  2EKX A;  3OVE A;  1NZV A;  3VGO A;  1JYU A;  3BKB A;  1CWD L;  1O41 A;  2CI8 A;  2GSB A;  1AYD A;  1BM2 A;  2SHP A;  2VIF A;  1R1Q A;  4OHL A;  4H34 A;  1CSY A;  2EYZ A;  4ROJ A;  1O4R A;  4JE4 A;  2LNW A;  1TZE E;  3CWG A;  5HKZ A;  1O4L A;  3IN7 A;  1A81 A;  4K44 A;  1A1A A;  1A1B A;  3VRO A;  3VRP A;  2CIA A;  3PS5 A;  3VS2 A;  1A07 A;  1BFJ A;  1LKK A;  1BKL A;  3TKZ A;  1O4E A;  4JEG A;  3M7F A;  2LQN A;  4FL3 A;  3UF4 A;  1LCK A;  2H46 E;  3QWX X;  2ROR A;  2DVJ A;  3MXY A;  3VS7 A;  1BFI A;  1M27 A;  5DC0 B;  1BHH B;  3VS1 A;  1QAD A;  1ZFP E;  3ZNI A;  2EOB A;  4LUD A;  3GQI B;  2FO0 A;  2CS0 A;  2HUW A;  2HCK A;  2PNB A;  4EIH A;  3IN8 A;  3OP0 A;  1Z3K A;  3PJP A;  2DCR A;  2RMX A;  3K2M A;  2EO3 A;  1CWE A;  1KA7 A;  1O4Q A;  3MAZ A;  1RJA A;  2DX0 A;  5AXI A;  1BG1 A;  2MC1 A;  2MRJ A;  3CBL A;  1KA6 A;  5EHR A;  4K11 A;  3OV1 A;  4NWG A;  2AOA A;  1OO3 A;  4LUE A;  3N7Y A;  3S9K A;  2MK2 A;  1P13 A;  5DF6 A;  5IBS A;  3QWY A;  2YSX A;  1CJ1 A;  3VS0 A;  1AOT F;  3UYO A;  1A08 A;  1CSZ A;  3EAZ A;  1R1S A;  3US4 A;  4F59 A;  1FBV A;  2Y1N A;  3BUN B;  1LUM A;  1B47 A;  1AB2 A;  2BBU A;  4E68 A;  4JGH A;  2K7A B;  1O4K A;  2L6K A;  2ETZ A;  2MRK A;  1AOU F;  4M4Z A;  2LCT A;  1LCJ A;  1K9A A;  4P9Z A;  3IMD A;  3HHM B;  3N84 A;  1O48 A;  1O4P A;  2DLY A;  4E93 A;  1RPY A;  1O4H A;  4K45 A;  4FL2 A;  5EEL A;  1MIL A;  1I3Z A;  3T04 A;  2C0O A;  2EO6 A;  2DM0 A;  3EAC A;  1BF5 A;  2B3O A;  3NHN A;  2H8H A;  1O45 A;  4U17 A;  3MXC A;  4DGP A;  1XA6 A;  2AUG A;  5DC4 A;  2RVF A;  1SKJ A;  4F5B A;  1BHF A;  1AYB A;  1O42 A;  2PTK A;  4WWQ A;  3TL0 A;  1KC2 A;  1UUS A;  1X0N A;  2H5K A;  1NZL A;  5EG3 B;  4OHE A;  5HKY A;  3PFV A;  1O44 A;  2JYQ A;  2XP1 A;  2LNX A;  2ABL A;  5I6V A;  1Y57 A;  4K2R A;  2IZV A;  2Y1M A;  3CXL A;  1KSW A;  2CI9 A;  1D4W A;  2EL8 A;  1D1Z A;  3VS3 A;  1AYA A;  1PIC A;  3HCK A;  1O4D A;  3C7I A;  1BLK A;  1NRV A;  1QG1 E;  1LKL A;  3VS4 A;  2QMS A;  1FBZ A;  2L4K A;  2DLZ A; 
#chains in the Genus database with same CATH topology
 1HCT B;  2Y3A B;  4XZ1 A;  3KFJ A;  5HKW A;  4D8K A;  1SPS A;  1IS0 A;  4FBN A;  4P9V A;  5D0J A;  4DGX A;  1BMB A;  3HIZ B;  2OQ1 A;  5BO4 A;  1O49 A;  2CR4 A;  1YVL A;  4X6S A;  1JYR A;  2IUH A;  1FYR A;  5EEQ A;  1O43 A;  4H1O A;  2LQW A;  2C0I A;  1Y1U A;  2C9W A;  5IBM A;  1FMK A;  1R1P A;  1SHD A;  2GE9 A;  2KNO A;  1OO4 A;  1A09 A;  1SPR A;  2HMH A;  1O4N A;  3WA4 A;  1AYC A;  4OHD A;  1FHS A;  2EU0 A;  3VRN A;  1F1W A;  3CD3 A;  3IMJ A;  3VS6 A;  2OZO A;  1X27 A;  4GL9 E;  2IUI A;  4OHH A;  1M61 A;  3OB1 B;  2PNA A;  1QCF A;  1O4B A;  5GJI A;  1X6C A;  5EHP A;  3LYV A;  1O4M A;  4NWF A;  1O47 A;  2CRH A;  1RQQ C;  1YVH A;  1BHH A;  2EYY A;  2LRA A;  2AOB A;  1O4A A;  1AD5 A;  3VS5 A;  3PQZ A;  3VRQ A;  2IUG A;  3BUM B;  1WQU A;  1UUR A;  2HDV A;  3BUX B;  1LUN A;  1JYQ A;  1OPL A;  4EY0 A;  1HCS B;  2CBL A;  2L3T A;  3VRR A;  1F2F A;  3S8O A;  3PLF B;  4U1P A;  5KAZ A;  1O46 A;  3VRZ A;  2EYV A;  2PLD A;  1OPK A;  2SRC A;  3BUO B;  5GJH A;  5DC9 A;  1FU6 A;  3PSK A;  1O4O A;  1O4I A;  1JU5 A;  4XZ0 A;  4GPL B;  2ECD A;  3BUW B;  1D4T A;  1O4F A;  1FU5 A;  2C0T A;  2MQI A;  1BKM A;  2K79 B;  1O4G A;  3N8M A;  3S8N A;  1O4C A;  1LUI A;  1A1E A;  4OHI A;  4L1B B;  2PLE A;  1JWO A;  3VRY A;  4QSY A;  5CDW A;  2RSY A;  1IJR A;  3GXX A;  1GHU A;  1BLJ A;  1O4J A;  4A4C A;  5AUL A;  1MW4 A;  3S8L A;  2HDX A;  3OB2 B;  1SHB A;  4GWF A;  4F5A A;  1H9O A;  1A1C A;  1LUK A;  4TZI A;  1TCE A;  1G83 A;  3PSJ A;  2KK6 A;  3GXW A;  1SHA A;  4A4B A;  5J3X A;  2YU7 A;  2FCI A;  1GRI A;  2EKX A;  3OVE A;  1NZV A;  3VGO A;  1JYU A;  3K2T A;  3BKB A;  1CWD L;  1O41 A;  2CI8 A;  2GSB A;  1AYD A;  1BM2 A;  2SHP A;  2VIF A;  1R1Q A;  4OHL A;  4H34 A;  1CSY A;  2EYZ A;  4ROJ A;  1O4R A;  4JE4 A;  2LNW A;  1TZE E;  3CWG A;  5HKZ A;  1O4L A;  3IN7 A;  1A81 A;  4K44 A;  1A1A A;  1A1B A;  3VRO A;  3VRP A;  2CIA A;  3PS5 A;  3VS2 A;  1A07 A;  1BFJ A;  1LKK A;  1BKL A;  3TKZ A;  1O4E A;  4JEG A;  3M7F A;  2LQN A;  4FL3 A;  3UF4 A;  1LCK A;  2H46 E;  3QWX X;  2ROR A;  2DVJ A;  3MXY A;  3VS7 A;  1BFI A;  1M27 A;  5DC0 B;  1BHH B;  3VS1 A;  1QAD A;  1ZFP E;  3ZNI A;  2EOB A;  4LUD A;  3GQI B;  2FO0 A;  2CS0 A;  2HUW A;  2HCK A;  2PNB A;  4EIH A;  3IN8 A;  3OP0 A;  1Z3K A;  3PJP A;  2DCR A;  2RMX A;  3K2M A;  2EO3 A;  1CWE A;  1KA7 A;  1O4Q A;  3MAZ A;  1RJA A;  2DX0 A;  5AXI A;  1BG1 A;  2MC1 A;  2MRJ A;  3CBL A;  1KA6 A;  2KGY A;  5EHR A;  4K11 A;  3OV1 A;  4NWG A;  2AOA A;  1OO3 A;  4LUE A;  3N7Y A;  3S9K A;  2MK2 A;  1P13 A;  5DF6 A;  5IBS A;  3QWY A;  2YSX A;  1CJ1 A;  3VS0 A;  1AOT F;  3UYO A;  1A08 A;  1CSZ A;  3EAZ A;  1R1S A;  3US4 A;  4F59 A;  1FBV A;  2Y1N A;  3BUN B;  1LUM A;  1B47 A;  1AB2 A;  2BBU A;  4E68 A;  4JGH A;  2K7A B;  1O4K A;  2L6K A;  2ETZ A;  2MRK A;  1AOU F;  4M4Z A;  2LCT A;  1LCJ A;  1K9A A;  4P9Z A;  3IMD A;  3HHM B;  3N84 A;  1O48 A;  1O4P A;  2DLY A;  4E93 A;  1RPY A;  1O4H A;  4K45 A;  4FL2 A;  5EEL A;  1MIL A;  1I3Z A;  3T04 A;  2C0O A;  2EO6 A;  2DM0 A;  3EAC A;  1BF5 A;  2B3O A;  3NHN A;  2H8H A;  1O45 A;  4U17 A;  3MXC A;  4DGP A;  1XA6 A;  2AUG A;  5DC4 A;  2RVF A;  1SKJ A;  4F5B A;  1BHF A;  1AYB A;  1O42 A;  2PTK A;  4WWQ A;  3TL0 A;  1KC2 A;  1UUS A;  1X0N A;  2H5K A;  1NZL A;  5EG3 B;  4OHE A;  5HKY A;  3PFV A;  1O44 A;  2JYQ A;  2XP1 A;  2LNX A;  2ABL A;  5I6V A;  1Y57 A;  4K2R A;  2IZV A;  2Y1M A;  3CXL A;  1KSW A;  2CI9 A;  1D4W A;  2EL8 A;  1D1Z A;  3VS3 A;  1AYA A;  1PIC A;  3HCK A;  1O4D A;  3C7I A;  1BLK A;  1NRV A;  1QG1 E;  1LKL A;  3VS4 A;  2QMS A;  1FBZ A;  2L4K A;  2DLZ A; 
#chains in the Genus database with same CATH homology
 1HCT B;  2Y3A B;  4XZ1 A;  3KFJ A;  5HKW A;  4D8K A;  1SPS A;  1IS0 A;  4FBN A;  4P9V A;  5D0J A;  4DGX A;  1BMB A;  3HIZ B;  2OQ1 A;  5BO4 A;  1O49 A;  2CR4 A;  1YVL A;  4X6S A;  1JYR A;  2IUH A;  1FYR A;  5EEQ A;  1O43 A;  4H1O A;  2LQW A;  2C0I A;  1Y1U A;  2C9W A;  5IBM A;  1FMK A;  1R1P A;  1SHD A;  2GE9 A;  2KNO A;  1OO4 A;  1A09 A;  1SPR A;  2HMH A;  1O4N A;  3WA4 A;  1AYC A;  4OHD A;  1FHS A;  2EU0 A;  3VRN A;  1F1W A;  3CD3 A;  3IMJ A;  3VS6 A;  2OZO A;  1X27 A;  4GL9 E;  2IUI A;  4OHH A;  1M61 A;  3OB1 B;  2PNA A;  1QCF A;  1O4B A;  5GJI A;  1X6C A;  5EHP A;  1O4M A;  4NWF A;  1O47 A;  2CRH A;  1RQQ C;  1YVH A;  1BHH A;  2EYY A;  2AOB A;  1O4A A;  1AD5 A;  3VS5 A;  3PQZ A;  3VRQ A;  2IUG A;  3BUM B;  1WQU A;  1UUR A;  2HDV A;  3BUX B;  1LUN A;  1JYQ A;  1OPL A;  4EY0 A;  1HCS B;  2CBL A;  2L3T A;  3VRR A;  1F2F A;  3S8O A;  3PLF B;  4U1P A;  5KAZ A;  1O46 A;  3VRZ A;  2EYV A;  2PLD A;  1OPK A;  2SRC A;  3BUO B;  5GJH A;  5DC9 A;  1FU6 A;  3PSK A;  1O4O A;  1O4I A;  1JU5 A;  4XZ0 A;  4GPL B;  2ECD A;  3BUW B;  1D4T A;  1O4F A;  1FU5 A;  2C0T A;  2MQI A;  1BKM A;  2K79 B;  1O4G A;  3N8M A;  3S8N A;  1O4C A;  1LUI A;  1A1E A;  4OHI A;  4L1B B;  2PLE A;  1JWO A;  3VRY A;  4QSY A;  5CDW A;  2RSY A;  1IJR A;  3GXX A;  1GHU A;  1BLJ A;  1O4J A;  4A4C A;  5AUL A;  1MW4 A;  3S8L A;  2HDX A;  3OB2 B;  1SHB A;  4GWF A;  4F5A A;  1H9O A;  1A1C A;  1LUK A;  4TZI A;  1TCE A;  1G83 A;  3PSJ A;  2KK6 A;  3GXW A;  1SHA A;  4A4B A;  5J3X A;  2YU7 A;  2FCI A;  1GRI A;  2EKX A;  3OVE A;  1NZV A;  3VGO A;  1JYU A;  3BKB A;  1CWD L;  1O41 A;  2CI8 A;  2GSB A;  1AYD A;  1BM2 A;  2SHP A;  2VIF A;  1R1Q A;  4OHL A;  4H34 A;  1CSY A;  2EYZ A;  4ROJ A;  1O4R A;  4JE4 A;  2LNW A;  1TZE E;  3CWG A;  5HKZ A;  1O4L A;  3IN7 A;  1A81 A;  4K44 A;  1A1A A;  1A1B A;  3VRO A;  3VRP A;  2CIA A;  3PS5 A;  3VS2 A;  1A07 A;  1BFJ A;  1LKK A;  1BKL A;  3TKZ A;  1O4E A;  4JEG A;  3M7F A;  2LQN A;  4FL3 A;  3UF4 A;  1LCK A;  2H46 E;  3QWX X;  2ROR A;  2DVJ A;  3MXY A;  3VS7 A;  1BFI A;  1M27 A;  5DC0 B;  1BHH B;  3VS1 A;  1QAD A;  1ZFP E;  3ZNI A;  2EOB A;  4LUD A;  3GQI B;  2FO0 A;  2CS0 A;  2HUW A;  2HCK A;  2PNB A;  4EIH A;  3IN8 A;  3OP0 A;  1Z3K A;  3PJP A;  2DCR A;  2RMX A;  3K2M A;  2EO3 A;  1CWE A;  1KA7 A;  1O4Q A;  3MAZ A;  1RJA A;  2DX0 A;  5AXI A;  1BG1 A;  2MC1 A;  2MRJ A;  3CBL A;  1KA6 A;  5EHR A;  4K11 A;  3OV1 A;  4NWG A;  2AOA A;  1OO3 A;  4LUE A;  3N7Y A;  3S9K A;  2MK2 A;  1P13 A;  5DF6 A;  5IBS A;  3QWY A;  2YSX A;  1CJ1 A;  3VS0 A;  1AOT F;  3UYO A;  1A08 A;  1CSZ A;  3EAZ A;  1R1S A;  3US4 A;  4F59 A;  1FBV A;  2Y1N A;  3BUN B;  1LUM A;  1B47 A;  1AB2 A;  2BBU A;  4E68 A;  4JGH A;  2K7A B;  1O4K A;  2L6K A;  2ETZ A;  2MRK A;  1AOU F;  4M4Z A;  2LCT A;  1LCJ A;  1K9A A;  4P9Z A;  3IMD A;  3HHM B;  3N84 A;  1O48 A;  1O4P A;  2DLY A;  4E93 A;  1RPY A;  1O4H A;  4K45 A;  4FL2 A;  5EEL A;  1MIL A;  1I3Z A;  3T04 A;  2C0O A;  2EO6 A;  2DM0 A;  3EAC A;  1BF5 A;  2B3O A;  3NHN A;  2H8H A;  1O45 A;  4U17 A;  3MXC A;  4DGP A;  1XA6 A;  2AUG A;  5DC4 A;  2RVF A;  1SKJ A;  4F5B A;  1BHF A;  1AYB A;  1O42 A;  2PTK A;  4WWQ A;  3TL0 A;  1KC2 A;  1UUS A;  1X0N A;  2H5K A;  1NZL A;  5EG3 B;  4OHE A;  5HKY A;  3PFV A;  1O44 A;  2JYQ A;  2XP1 A;  2LNX A;  2ABL A;  5I6V A;  1Y57 A;  4K2R A;  2IZV A;  2Y1M A;  3CXL A;  1KSW A;  2CI9 A;  1D4W A;  2EL8 A;  1D1Z A;  3VS3 A;  1AYA A;  1PIC A;  3HCK A;  1O4D A;  3C7I A;  1BLK A;  1NRV A;  1QG1 E;  1LKL A;  3VS4 A;  2QMS A;  1FBZ A;  2L4K A;  2DLZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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