4FBNA

Insights into structural integration of the plcgamma regulatory region and mechanism of autoinhibition and activation based on key roles of sh2 domains
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
243
structure length
232
Chain Sequence
NEKWFHGKLGAGDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGYVEANPM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Homo sapiens
publication title Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation.
pubmed doi rcsb
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
total genus 58
structure length 232
sequence length 243
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2012-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4fbnA02
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4fbnA01
1O4AA 1GRIA 1A1BA 1D1ZA 4E93A 2L3TA 1KA7A 1HCSB 2DCRA 2OZOA 1QCFA 4P9ZA 5EHPA 3VS2A 4JEGA 1A1AA 2LNWA 2EL8A 2DLYA 5HKWA 5DF6A 2H5KA 1M61A 2LCTA 1Y1UA 1UURA 2EO6A 5AULA 4FBNA 1BHHB 1JWOA 2EU0A 1FBZA 1A81A 3S8OA 5DC9A 5EHRA 1KC2A 2XP1A 4GWFA 2H8HA 3VS4A 4D8KA 2CS0A 2LQNA 5EG3B 1A08A 1SKJA 1CWEA 2BBUA 1AYCA 1CJ1A 2VIFA 1SPRA 2DM0A 4QSYA 3PLFB 2PNBA 2FCIA 5EEQA 5HKZA 3KFJA 5AXIA 1AYBA 3EACA 2EYVA 1BFIA 4EIHA 3QWXX 1A1EA 2CRHA 2CR4A 5I6VA 1O4FA 1RPYA 1O4LA 2MK2A 3M7FA 2HDVA 1BM2A 2MRJA 1O48A 1KSWA 3IMJA 1YVLA 1K9AA 1F1WA 1TZEE 2HMHA 3MAZA 1LUMA 1KA6A 2DVJA 1O43A 2C0TA 3VS1A 3S8LA 4P9VA 1FBVA 4NWGA 3S8NA 1Y57A 1UUSA 1X27A 3VS5A 1AYAA 1JYQA 3OV1A 4OHDA 2LQWA 3QWYA 3CBLA 1NZLA 1RQQC 5HKYA 1O4BA 1OO3A 2SRCA 2HCKA 1TCEA 4NWFA 4X6SA 1R1SA 1X6CA 3VS7A 1OO4A 4F5BA 2C0IA 2CI8A 1PICA 1LUIA 1XA6A 1LKLA 1LCJA 3N84A 1CSZA 3VRPA 2JYQA 3HIZB 4A4CA 1O4HA 3PS5A 1D4TA 1AOUF 3C7IA 1SHDA 3VRQA 1IJRA 3BUNB 3UYOA 2RORA 2LNXA 3TL0A 4JGHA 3VS0A 3ZNIA 2PLDA 1I3ZA 1R1PA 1O4DA 1BMBA 4ROJA 1HCTB 3N7YA 4L1BB 5GJHA 2C0OA 2DX0A 1O45A 5BO4A 1BFJA 1D4WA 3BUOB 1LUNA 1FU5A 3PQZA 1F2FA 4K11A 1AD5A 2K7AB 4FL3A 2AOBA 1YVHA 3OP0A 1NZVA 4JE4A 2CIAA 2CBLA 2IZVA 5KAZA 3HHMB 3N8MA 3BUXB 1O4GA 2EYYA 1AB2A 2Y1MA 1OPLA 3HCKA 2Y3AB 3VROA 2PLEA 1BLJA 1P13A 1ZFPE 2C9WA 2ECDA 3OB1B 3WA4A 2OQ1A 4GPLB 2RVFA 4FL2A 1BKMA 3VRNA 1B47A 1G83A 3IMDA 4GL9E 3MXYA 1O4QA 3GXWA 1O4CA 3OVEA 2KNOA 1O4RA 2RMXA 3PFVA 5CDWA 2PNAA 4U1PA 5EELA 3IN7A 1JU5A 4H34A 3VS6A 5GJIA 1O44A 2EKXA 1SHAA 1O4NA 2PTKA 3EAZA 2GSBA 4F5AA 1H9OA 2YU7A 1O4KA 3TKZA 1JYUA 1O4EA 2FO0A 4K2RA 4U17A 4LUDA 3PSKA 4EY0A 1NRVA 1BG1A 2RSYA 2SHPA 1O49A 3UF4A 3VRZA 2ETZA 1JYRA 5D0JA 1FHSA 1IS0A 2L4KA 3T04A 1LCKA 1BF5A 5DC0B 2HDXA 4OHIA 1QG1E 3GXXA 1M27A 4OHHA 4XZ0A 3VS3A 2EO3A 3VRRA 2QMSA 1WQUA 3PSJA 4K45A 1X0NA 1MW4A 1O4PA 4XZ1A 1RJAA 1Z3KA 4OHEA 1BLKA 1LKKA 4WWQA 3IN8A 2MC1A 4OHLA 1O47A 1SHBA 4DGXA 4A4BA 1AYDA 2DLZA 3OB2B 5DC4A 4F59A 2K79B 3K2MA 2GE9A 1BHFA 3NHNA 1A1CA 2L6KA 3CD3A 2B3OA 2IUHA 1GHUA 1O4JA 2AOAA 1CSYA 1FMKA 1O42A 1FU6A 5IBSA 2MQIA 1O46A 2H46E 1AOTF 2Y1NA 1O4MA 4TZIA 3BUMB 3BKBA 4LUEA 1O4IA 3GQIB 2EOBA 2ABLA 2IUIA 4H1OA 3PJPA 3VGOA 3US4A 1A09A 1QADA 2MRKA 2YSXA 3CXLA 1BHHA 1O4OA 1O41A 1A07A 4K44A 2KK6A 1SPSA 3BUWB 4DGPA 3S9KA 2HUWA 1FYRA 5J3XA 3CWGA 3VRYA 1OPKA 1MILA 1R1QA 2EYZA 1BKLA 1LUKA 4M4ZA 2AUGA 1CWDL 2CI9A 2IUGA 4E68A 5IBMA 3MXCA
chains in the Genus database with same CATH superfamily
1O4AA 1GRIA 1A1BA 1D1ZA 4E93A 2L3TA 1KA7A 1HCSB 2DCRA 2OZOA 1QCFA 4P9ZA 5EHPA 3VS2A 4JEGA 1A1AA 2LNWA 2EL8A 2DLYA 5HKWA 5DF6A 2H5KA 1M61A 2LCTA 1Y1UA 1UURA 2EO6A 5AULA 4FBNA 1BHHB 1JWOA 2EU0A 1FBZA 1A81A 3S8OA 5DC9A 5EHRA 1KC2A 2XP1A 4GWFA 2H8HA 3VS4A 2LRAA 4D8KA 2CS0A 2LQNA 5EG3B 1A08A 1SKJA 1CWEA 2BBUA 1AYCA 1CJ1A 2VIFA 1SPRA 2DM0A 4QSYA 3PLFB 2PNBA 2FCIA 5EEQA 5HKZA 3KFJA 5AXIA 1AYBA 3EACA 2EYVA 1BFIA 4EIHA 3QWXX 1A1EA 2CRHA 2CR4A 5I6VA 1O4FA 1RPYA 1O4LA 2MK2A 3M7FA 2HDVA 1BM2A 2MRJA 1O48A 1KSWA 3IMJA 1YVLA 1K9AA 1F1WA 1TZEE 2HMHA 3MAZA 1LUMA 1KA6A 2DVJA 1O43A 2C0TA 3VS1A 3S8LA 4P9VA 1FBVA 4NWGA 3S8NA 1Y57A 1UUSA 1X27A 3VS5A 1AYAA 1JYQA 3OV1A 4OHDA 2LQWA 3QWYA 3CBLA 1NZLA 1RQQC 5HKYA 1O4BA 1OO3A 2SRCA 2HCKA 1TCEA 4NWFA 4X6SA 1R1SA 1X6CA 3VS7A 1OO4A 4F5BA 2C0IA 2CI8A 1PICA 1LUIA 1XA6A 1LKLA 1LCJA 3N84A 1CSZA 3VRPA 2JYQA 3HIZB 4A4CA 1O4HA 3PS5A 1D4TA 1AOUF 3C7IA 1SHDA 3VRQA 1IJRA 3BUNB 3UYOA 2RORA 2LNXA 3TL0A 4JGHA 3VS0A 3ZNIA 2PLDA 1I3ZA 1R1PA 1O4DA 1BMBA 4ROJA 1HCTB 3N7YA 4L1BB 5GJHA 2C0OA 2DX0A 1O45A 5BO4A 1BFJA 1D4WA 3BUOB 1LUNA 1FU5A 3PQZA 1F2FA 4K11A 1AD5A 2K7AB 4FL3A 2AOBA 1YVHA 3OP0A 1NZVA 4JE4A 2CIAA 2CBLA 2IZVA 2KGYA 5KAZA 3HHMB 3N8MA 3BUXB 1O4GA 2EYYA 1AB2A 2Y1MA 1OPLA 3HCKA 2Y3AB 3VROA 2PLEA 1BLJA 1P13A 1ZFPE 2C9WA 2ECDA 3OB1B 3WA4A 2OQ1A 4GPLB 2RVFA 4FL2A 1BKMA 3VRNA 1B47A 1G83A 3IMDA 4GL9E 3MXYA 1O4QA 3GXWA 1O4CA 3OVEA 2KNOA 1O4RA 2RMXA 3PFVA 5CDWA 2PNAA 4U1PA 5EELA 3IN7A 1JU5A 4H34A 3VS6A 5GJIA 1O44A 2EKXA 1SHAA 1O4NA 2PTKA 3EAZA 2GSBA 4F5AA 1H9OA 2YU7A 1O4KA 3TKZA 1JYUA 1O4EA 2FO0A 4K2RA 4U17A 4LUDA 3PSKA 4EY0A 3K2TA 1NRVA 1BG1A 2RSYA 2SHPA 1O49A 3UF4A 3VRZA 2ETZA 1JYRA 5D0JA 1FHSA 1IS0A 2L4KA 3T04A 1LCKA 1BF5A 5DC0B 2HDXA 4OHIA 1QG1E 3GXXA 1M27A 4OHHA 4XZ0A 3VS3A 2EO3A 3VRRA 2QMSA 1WQUA 3PSJA 4K45A 1X0NA 1MW4A 1O4PA 4XZ1A 1RJAA 1Z3KA 4OHEA 1BLKA 1LKKA 4WWQA 3IN8A 2MC1A 4OHLA 1O47A 1SHBA 4DGXA 4A4BA 1AYDA 2DLZA 3OB2B 5DC4A 4F59A 2K79B 3K2MA 2GE9A 1BHFA 3NHNA 1A1CA 2L6KA 3CD3A 2B3OA 2IUHA 1GHUA 1O4JA 2AOAA 1CSYA 1FMKA 1O42A 1FU6A 5IBSA 2MQIA 1O46A 2H46E 1AOTF 2Y1NA 1O4MA 4TZIA 3BUMB 3BKBA 4LUEA 1O4IA 3GQIB 2EOBA 2ABLA 2IUIA 4H1OA 3PJPA 3VGOA 3US4A 1A09A 1QADA 2MRKA 2YSXA 3CXLA 1BHHA 1O4OA 1O41A 1A07A 4K44A 2KK6A 1SPSA 3BUWB 4DGPA 3S9KA 2HUWA 1FYRA 5J3XA 3CWGA 3VRYA 1OPKA 3LYVA 1MILA 1R1QA 2EYZA 1BKLA 1LUKA 4M4ZA 2AUGA 1CWDL 2CI9A 2IUGA 4E68A 5IBMA 3MXCA
chains in the Genus database with same CATH topology
1O4AA 1GRIA 1A1BA 1D1ZA 4E93A 2L3TA 1KA7A 1HCSB 2DCRA 2OZOA 1QCFA 4P9ZA 5EHPA 3VS2A 4JEGA 1A1AA 2LNWA 2EL8A 2DLYA 5HKWA 5DF6A 2H5KA 1M61A 2LCTA 1Y1UA 1UURA 2EO6A 5AULA 4FBNA 1BHHB 1JWOA 2EU0A 1FBZA 1A81A 3S8OA 5DC9A 5EHRA 1KC2A 2XP1A 4GWFA 2H8HA 3VS4A 4D8KA 2CS0A 2LQNA 5EG3B 1A08A 1SKJA 1CWEA 2BBUA 1AYCA 1CJ1A 2VIFA 1SPRA 2DM0A 4QSYA 3PLFB 2PNBA 2FCIA 5EEQA 5HKZA 3KFJA 5AXIA 1AYBA 3EACA 2EYVA 1BFIA 4EIHA 3QWXX 1A1EA 2CRHA 2CR4A 5I6VA 1O4FA 1RPYA 1O4LA 2MK2A 3M7FA 2HDVA 1BM2A 2MRJA 1O48A 1KSWA 3IMJA 1YVLA 1K9AA 1F1WA 1TZEE 2HMHA 3MAZA 1LUMA 1KA6A 2DVJA 1O43A 2C0TA 3VS1A 3S8LA 4P9VA 1FBVA 4NWGA 3S8NA 1Y57A 1UUSA 1X27A 3VS5A 1AYAA 1JYQA 3OV1A 4OHDA 2LQWA 3QWYA 3CBLA 1NZLA 1RQQC 5HKYA 1O4BA 1OO3A 2SRCA 2HCKA 1TCEA 4NWFA 4X6SA 1R1SA 1X6CA 3VS7A 1OO4A 4F5BA 2C0IA 2CI8A 1PICA 1LUIA 1XA6A 1LKLA 1LCJA 3N84A 1CSZA 3VRPA 2JYQA 3HIZB 4A4CA 1O4HA 3PS5A 1D4TA 1AOUF 3C7IA 1SHDA 3VRQA 1IJRA 3BUNB 3UYOA 2RORA 2LNXA 3TL0A 4JGHA 3VS0A 3ZNIA 2PLDA 1I3ZA 1R1PA 1O4DA 1BMBA 4ROJA 1HCTB 3N7YA 4L1BB 5GJHA 2C0OA 2DX0A 1O45A 5BO4A 1BFJA 1D4WA 3BUOB 1LUNA 1FU5A 3PQZA 1F2FA 4K11A 1AD5A 2K7AB 4FL3A 2AOBA 1YVHA 3OP0A 1NZVA 4JE4A 2CIAA 2CBLA 2IZVA 5KAZA 3HHMB 3N8MA 3BUXB 1O4GA 2EYYA 1AB2A 2Y1MA 1OPLA 3HCKA 2Y3AB 3VROA 2PLEA 1BLJA 1P13A 1ZFPE 2C9WA 2ECDA 3OB1B 3WA4A 2OQ1A 4GPLB 2RVFA 4FL2A 1BKMA 3VRNA 1B47A 1G83A 3IMDA 4GL9E 3MXYA 1O4QA 3GXWA 1O4CA 3OVEA 2KNOA 1O4RA 2RMXA 3PFVA 5CDWA 2PNAA 4U1PA 5EELA 3IN7A 1JU5A 4H34A 3VS6A 5GJIA 1O44A 2EKXA 1SHAA 1O4NA 2PTKA 3EAZA 2GSBA 4F5AA 1H9OA 2YU7A 1O4KA 3TKZA 1JYUA 1O4EA 2FO0A 4K2RA 4U17A 4LUDA 3PSKA 4EY0A 1NRVA 1BG1A 2RSYA 2SHPA 1O49A 3UF4A 3VRZA 2ETZA 1JYRA 5D0JA 1FHSA 1IS0A 2L4KA 3T04A 1LCKA 1BF5A 5DC0B 2HDXA 4OHIA 1QG1E 3GXXA 1M27A 4OHHA 4XZ0A 3VS3A 2EO3A 3VRRA 2QMSA 1WQUA 3PSJA 4K45A 1X0NA 1MW4A 1O4PA 4XZ1A 1RJAA 1Z3KA 4OHEA 1BLKA 1LKKA 4WWQA 3IN8A 2MC1A 4OHLA 1O47A 1SHBA 4DGXA 4A4BA 1AYDA 2DLZA 3OB2B 5DC4A 4F59A 2K79B 3K2MA 2GE9A 1BHFA 3NHNA 1A1CA 2L6KA 3CD3A 2B3OA 2IUHA 1GHUA 1O4JA 2AOAA 1CSYA 1FMKA 1O42A 1FU6A 5IBSA 2MQIA 1O46A 2H46E 1AOTF 2Y1NA 1O4MA 4TZIA 3BUMB 3BKBA 4LUEA 1O4IA 3GQIB 2EOBA 2ABLA 2IUIA 4H1OA 3PJPA 3VGOA 3US4A 1A09A 1QADA 2MRKA 2YSXA 3CXLA 1BHHA 1O4OA 1O41A 1A07A 4K44A 2KK6A 1SPSA 3BUWB 4DGPA 3S9KA 2HUWA 1FYRA 5J3XA 3CWGA 3VRYA 1OPKA 1MILA 1R1QA 2EYZA 1BKLA 1LUKA 4M4ZA 2AUGA 1CWDL 2CI9A 2IUGA 4E68A 5IBMA 3MXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O4A A;  1GRI A;  1A1B A;  1D1Z A;  4E93 A;  2L3T A;  1KA7 A;  1HCS B;  2DCR A;  2OZO A;  1QCF A;  4P9Z A;  5EHP A;  3VS2 A;  4JEG A;  1A1A A;  2LNW A;  2EL8 A;  2DLY A;  5HKW A;  5DF6 A;  2H5K A;  1M61 A;  2LCT A;  1Y1U A;  1UUR A;  2EO6 A;  5AUL A;  4FBN A;  1BHH B;  1JWO A;  2EU0 A;  1FBZ A;  1A81 A;  3S8O A;  5DC9 A;  5EHR A;  1KC2 A;  2XP1 A;  4GWF A;  2H8H A;  3VS4 A;  4D8K A;  2CS0 A;  2LQN A;  5EG3 B;  1A08 A;  1SKJ A;  1CWE A;  2BBU A;  1AYC A;  1CJ1 A;  2VIF A;  1SPR A;  2DM0 A;  4QSY A;  3PLF B;  2PNB A;  2FCI A;  5EEQ A;  5HKZ A;  3KFJ A;  5AXI A;  1AYB A;  3EAC A;  2EYV A;  1BFI A;  4EIH A;  3QWX X;  1A1E A;  2CRH A;  2CR4 A;  5I6V A;  1O4F A;  1RPY A;  1O4L A;  2MK2 A;  3M7F A;  2HDV A;  1BM2 A;  2MRJ A;  1O48 A;  1KSW A;  3IMJ A;  1YVL A;  1K9A A;  1F1W A;  1TZE E;  2HMH A;  3MAZ A;  1LUM A;  1KA6 A;  2DVJ A;  1O43 A;  2C0T A;  3VS1 A;  3S8L A;  4P9V A;  1FBV A;  4NWG A;  3S8N A;  1Y57 A;  1UUS A;  1X27 A;  3VS5 A;  1AYA A;  1JYQ A;  3OV1 A;  4OHD A;  2LQW A;  3QWY A;  3CBL A;  1NZL A;  1RQQ C;  5HKY A;  1O4B A;  1OO3 A;  2SRC A;  2HCK A;  1TCE A;  4NWF A;  4X6S A;  1R1S A;  1X6C A;  3VS7 A;  1OO4 A;  4F5B A;  2C0I A;  2CI8 A;  1PIC A;  1LUI A;  1XA6 A;  1LKL A;  1LCJ A;  3N84 A;  1CSZ A;  3VRP A;  2JYQ A;  3HIZ B;  4A4C A;  1O4H A;  3PS5 A;  1D4T A;  1AOU F;  3C7I A;  1SHD A;  3VRQ A;  1IJR A;  3BUN B;  3UYO A;  2ROR A;  2LNX A;  3TL0 A;  4JGH A;  3VS0 A;  3ZNI A;  2PLD A;  1I3Z A;  1R1P A;  1O4D A;  1BMB A;  4ROJ A;  1HCT B;  3N7Y A;  4L1B B;  5GJH A;  2C0O A;  2DX0 A;  1O45 A;  5BO4 A;  1BFJ A;  1D4W A;  3BUO B;  1LUN A;  1FU5 A;  3PQZ A;  1F2F A;  4K11 A;  1AD5 A;  2K7A B;  4FL3 A;  2AOB A;  1YVH A;  3OP0 A;  1NZV A;  4JE4 A;  2CIA A;  2CBL A;  2IZV A;  5KAZ A;  3HHM B;  3N8M A;  3BUX B;  1O4G A;  2EYY A;  1AB2 A;  2Y1M A;  1OPL A;  3HCK A;  2Y3A B;  3VRO A;  2PLE A;  1BLJ A;  1P13 A;  1ZFP E;  2C9W A;  2ECD A;  3OB1 B;  3WA4 A;  2OQ1 A;  4GPL B;  2RVF A;  4FL2 A;  1BKM A;  3VRN A;  1B47 A;  1G83 A;  3IMD A;  4GL9 E;  3MXY A;  1O4Q A;  3GXW A;  1O4C A;  3OVE A;  2KNO A;  1O4R A;  2RMX A;  3PFV A;  5CDW A;  2PNA A;  4U1P A;  5EEL A;  3IN7 A;  1JU5 A;  4H34 A;  3VS6 A;  5GJI A;  1O44 A;  2EKX A;  1SHA A;  1O4N A;  2PTK A;  3EAZ A;  2GSB A;  4F5A A;  1H9O A;  2YU7 A;  1O4K A;  3TKZ A;  1JYU A;  1O4E A;  2FO0 A;  4K2R A;  4U17 A;  4LUD A;  3PSK A;  4EY0 A;  1NRV A;  1BG1 A;  2RSY A;  2SHP A;  1O49 A;  3UF4 A;  3VRZ A;  2ETZ A;  1JYR A;  5D0J A;  1FHS A;  1IS0 A;  2L4K A;  3T04 A;  1LCK A;  1BF5 A;  5DC0 B;  2HDX A;  4OHI A;  1QG1 E;  3GXX A;  1M27 A;  4OHH A;  4XZ0 A;  3VS3 A;  2EO3 A;  3VRR A;  2QMS A;  1WQU A;  3PSJ A;  4K45 A;  1X0N A;  1MW4 A;  1O4P A;  4XZ1 A;  1RJA A;  1Z3K A;  4OHE A;  1BLK A;  1LKK A;  4WWQ A;  3IN8 A;  2MC1 A;  4OHL A;  1O47 A;  1SHB A;  4DGX A;  4A4B A;  1AYD A;  2DLZ A;  3OB2 B;  5DC4 A;  4F59 A;  2K79 B;  3K2M A;  2GE9 A;  1BHF A;  3NHN A;  1A1C A;  2L6K A;  3CD3 A;  2B3O A;  2IUH A;  1GHU A;  1O4J A;  2AOA A;  1CSY A;  1FMK A;  1O42 A;  1FU6 A;  5IBS A;  2MQI A;  1O46 A;  2H46 E;  1AOT F;  2Y1N A;  1O4M A;  4TZI A;  3BUM B;  3BKB A;  4LUE A;  1O4I A;  3GQI B;  2EOB A;  2ABL A;  2IUI A;  4H1O A;  3PJP A;  3VGO A;  3US4 A;  1A09 A;  1QAD A;  2MRK A;  2YSX A;  3CXL A;  1BHH A;  1O4O A;  1O41 A;  1A07 A;  4K44 A;  2KK6 A;  1SPS A;  3BUW B;  4DGP A;  3S9K A;  2HUW A;  1FYR A;  5J3X A;  3CWG A;  3VRY A;  1OPK A;  1MIL A;  1R1Q A;  2EYZ A;  1BKL A;  1LUK A;  4M4Z A;  2AUG A;  1CWD L;  2CI9 A;  2IUG A;  4E68 A;  5IBM A;  3MXC A; 
#chains in the Genus database with same CATH topology
 1O4A A;  1GRI A;  1A1B A;  1D1Z A;  4E93 A;  2L3T A;  1KA7 A;  1HCS B;  2DCR A;  2OZO A;  1QCF A;  4P9Z A;  5EHP A;  3VS2 A;  4JEG A;  1A1A A;  2LNW A;  2EL8 A;  2DLY A;  5HKW A;  5DF6 A;  2H5K A;  1M61 A;  2LCT A;  1Y1U A;  1UUR A;  2EO6 A;  5AUL A;  4FBN A;  1BHH B;  1JWO A;  2EU0 A;  1FBZ A;  1A81 A;  3S8O A;  5DC9 A;  5EHR A;  1KC2 A;  2XP1 A;  4GWF A;  2H8H A;  3VS4 A;  2LRA A;  4D8K A;  2CS0 A;  2LQN A;  5EG3 B;  1A08 A;  1SKJ A;  1CWE A;  2BBU A;  1AYC A;  1CJ1 A;  2VIF A;  1SPR A;  2DM0 A;  4QSY A;  3PLF B;  2PNB A;  2FCI A;  5EEQ A;  5HKZ A;  3KFJ A;  5AXI A;  1AYB A;  3EAC A;  2EYV A;  1BFI A;  4EIH A;  3QWX X;  1A1E A;  2CRH A;  2CR4 A;  5I6V A;  1O4F A;  1RPY A;  1O4L A;  2MK2 A;  3M7F A;  2HDV A;  1BM2 A;  2MRJ A;  1O48 A;  1KSW A;  3IMJ A;  1YVL A;  1K9A A;  1F1W A;  1TZE E;  2HMH A;  3MAZ A;  1LUM A;  1KA6 A;  2DVJ A;  1O43 A;  2C0T A;  3VS1 A;  3S8L A;  4P9V A;  1FBV A;  4NWG A;  3S8N A;  1Y57 A;  1UUS A;  1X27 A;  3VS5 A;  1AYA A;  1JYQ A;  3OV1 A;  4OHD A;  2LQW A;  3QWY A;  3CBL A;  1NZL A;  1RQQ C;  5HKY A;  1O4B A;  1OO3 A;  2SRC A;  2HCK A;  1TCE A;  4NWF A;  4X6S A;  1R1S A;  1X6C A;  3VS7 A;  1OO4 A;  4F5B A;  2C0I A;  2CI8 A;  1PIC A;  1LUI A;  1XA6 A;  1LKL A;  1LCJ A;  3N84 A;  1CSZ A;  3VRP A;  2JYQ A;  3HIZ B;  4A4C A;  1O4H A;  3PS5 A;  1D4T A;  1AOU F;  3C7I A;  1SHD A;  3VRQ A;  1IJR A;  3BUN B;  3UYO A;  2ROR A;  2LNX A;  3TL0 A;  4JGH A;  3VS0 A;  3ZNI A;  2PLD A;  1I3Z A;  1R1P A;  1O4D A;  1BMB A;  4ROJ A;  1HCT B;  3N7Y A;  4L1B B;  5GJH A;  2C0O A;  2DX0 A;  1O45 A;  5BO4 A;  1BFJ A;  1D4W A;  3BUO B;  1LUN A;  1FU5 A;  3PQZ A;  1F2F A;  4K11 A;  1AD5 A;  2K7A B;  4FL3 A;  2AOB A;  1YVH A;  3OP0 A;  1NZV A;  4JE4 A;  2CIA A;  2CBL A;  2IZV A;  2KGY A;  5KAZ A;  3HHM B;  3N8M A;  3BUX B;  1O4G A;  2EYY A;  1AB2 A;  2Y1M A;  1OPL A;  3HCK A;  2Y3A B;  3VRO A;  2PLE A;  1BLJ A;  1P13 A;  1ZFP E;  2C9W A;  2ECD A;  3OB1 B;  3WA4 A;  2OQ1 A;  4GPL B;  2RVF A;  4FL2 A;  1BKM A;  3VRN A;  1B47 A;  1G83 A;  3IMD A;  4GL9 E;  3MXY A;  1O4Q A;  3GXW A;  1O4C A;  3OVE A;  2KNO A;  1O4R A;  2RMX A;  3PFV A;  5CDW A;  2PNA A;  4U1P A;  5EEL A;  3IN7 A;  1JU5 A;  4H34 A;  3VS6 A;  5GJI A;  1O44 A;  2EKX A;  1SHA A;  1O4N A;  2PTK A;  3EAZ A;  2GSB A;  4F5A A;  1H9O A;  2YU7 A;  1O4K A;  3TKZ A;  1JYU A;  1O4E A;  2FO0 A;  4K2R A;  4U17 A;  4LUD A;  3PSK A;  4EY0 A;  3K2T A;  1NRV A;  1BG1 A;  2RSY A;  2SHP A;  1O49 A;  3UF4 A;  3VRZ A;  2ETZ A;  1JYR A;  5D0J A;  1FHS A;  1IS0 A;  2L4K A;  3T04 A;  1LCK A;  1BF5 A;  5DC0 B;  2HDX A;  4OHI A;  1QG1 E;  3GXX A;  1M27 A;  4OHH A;  4XZ0 A;  3VS3 A;  2EO3 A;  3VRR A;  2QMS A;  1WQU A;  3PSJ A;  4K45 A;  1X0N A;  1MW4 A;  1O4P A;  4XZ1 A;  1RJA A;  1Z3K A;  4OHE A;  1BLK A;  1LKK A;  4WWQ A;  3IN8 A;  2MC1 A;  4OHL A;  1O47 A;  1SHB A;  4DGX A;  4A4B A;  1AYD A;  2DLZ A;  3OB2 B;  5DC4 A;  4F59 A;  2K79 B;  3K2M A;  2GE9 A;  1BHF A;  3NHN A;  1A1C A;  2L6K A;  3CD3 A;  2B3O A;  2IUH A;  1GHU A;  1O4J A;  2AOA A;  1CSY A;  1FMK A;  1O42 A;  1FU6 A;  5IBS A;  2MQI A;  1O46 A;  2H46 E;  1AOT F;  2Y1N A;  1O4M A;  4TZI A;  3BUM B;  3BKB A;  4LUE A;  1O4I A;  3GQI B;  2EOB A;  2ABL A;  2IUI A;  4H1O A;  3PJP A;  3VGO A;  3US4 A;  1A09 A;  1QAD A;  2MRK A;  2YSX A;  3CXL A;  1BHH A;  1O4O A;  1O41 A;  1A07 A;  4K44 A;  2KK6 A;  1SPS A;  3BUW B;  4DGP A;  3S9K A;  2HUW A;  1FYR A;  5J3X A;  3CWG A;  3VRY A;  1OPK A;  3LYV A;  1MIL A;  1R1Q A;  2EYZ A;  1BKL A;  1LUK A;  4M4Z A;  2AUG A;  1CWD L;  2CI9 A;  2IUG A;  4E68 A;  5IBM A;  3MXC A; 
#chains in the Genus database with same CATH homology
 1O4A A;  1GRI A;  1A1B A;  1D1Z A;  4E93 A;  2L3T A;  1KA7 A;  1HCS B;  2DCR A;  2OZO A;  1QCF A;  4P9Z A;  5EHP A;  3VS2 A;  4JEG A;  1A1A A;  2LNW A;  2EL8 A;  2DLY A;  5HKW A;  5DF6 A;  2H5K A;  1M61 A;  2LCT A;  1Y1U A;  1UUR A;  2EO6 A;  5AUL A;  4FBN A;  1BHH B;  1JWO A;  2EU0 A;  1FBZ A;  1A81 A;  3S8O A;  5DC9 A;  5EHR A;  1KC2 A;  2XP1 A;  4GWF A;  2H8H A;  3VS4 A;  4D8K A;  2CS0 A;  2LQN A;  5EG3 B;  1A08 A;  1SKJ A;  1CWE A;  2BBU A;  1AYC A;  1CJ1 A;  2VIF A;  1SPR A;  2DM0 A;  4QSY A;  3PLF B;  2PNB A;  2FCI A;  5EEQ A;  5HKZ A;  3KFJ A;  5AXI A;  1AYB A;  3EAC A;  2EYV A;  1BFI A;  4EIH A;  3QWX X;  1A1E A;  2CRH A;  2CR4 A;  5I6V A;  1O4F A;  1RPY A;  1O4L A;  2MK2 A;  3M7F A;  2HDV A;  1BM2 A;  2MRJ A;  1O48 A;  1KSW A;  3IMJ A;  1YVL A;  1K9A A;  1F1W A;  1TZE E;  2HMH A;  3MAZ A;  1LUM A;  1KA6 A;  2DVJ A;  1O43 A;  2C0T A;  3VS1 A;  3S8L A;  4P9V A;  1FBV A;  4NWG A;  3S8N A;  1Y57 A;  1UUS A;  1X27 A;  3VS5 A;  1AYA A;  1JYQ A;  3OV1 A;  4OHD A;  2LQW A;  3QWY A;  3CBL A;  1NZL A;  1RQQ C;  5HKY A;  1O4B A;  1OO3 A;  2SRC A;  2HCK A;  1TCE A;  4NWF A;  4X6S A;  1R1S A;  1X6C A;  3VS7 A;  1OO4 A;  4F5B A;  2C0I A;  2CI8 A;  1PIC A;  1LUI A;  1XA6 A;  1LKL A;  1LCJ A;  3N84 A;  1CSZ A;  3VRP A;  2JYQ A;  3HIZ B;  4A4C A;  1O4H A;  3PS5 A;  1D4T A;  1AOU F;  3C7I A;  1SHD A;  3VRQ A;  1IJR A;  3BUN B;  3UYO A;  2ROR A;  2LNX A;  3TL0 A;  4JGH A;  3VS0 A;  3ZNI A;  2PLD A;  1I3Z A;  1R1P A;  1O4D A;  1BMB A;  4ROJ A;  1HCT B;  3N7Y A;  4L1B B;  5GJH A;  2C0O A;  2DX0 A;  1O45 A;  5BO4 A;  1BFJ A;  1D4W A;  3BUO B;  1LUN A;  1FU5 A;  3PQZ A;  1F2F A;  4K11 A;  1AD5 A;  2K7A B;  4FL3 A;  2AOB A;  1YVH A;  3OP0 A;  1NZV A;  4JE4 A;  2CIA A;  2CBL A;  2IZV A;  5KAZ A;  3HHM B;  3N8M A;  3BUX B;  1O4G A;  2EYY A;  1AB2 A;  2Y1M A;  1OPL A;  3HCK A;  2Y3A B;  3VRO A;  2PLE A;  1BLJ A;  1P13 A;  1ZFP E;  2C9W A;  2ECD A;  3OB1 B;  3WA4 A;  2OQ1 A;  4GPL B;  2RVF A;  4FL2 A;  1BKM A;  3VRN A;  1B47 A;  1G83 A;  3IMD A;  4GL9 E;  3MXY A;  1O4Q A;  3GXW A;  1O4C A;  3OVE A;  2KNO A;  1O4R A;  2RMX A;  3PFV A;  5CDW A;  2PNA A;  4U1P A;  5EEL A;  3IN7 A;  1JU5 A;  4H34 A;  3VS6 A;  5GJI A;  1O44 A;  2EKX A;  1SHA A;  1O4N A;  2PTK A;  3EAZ A;  2GSB A;  4F5A A;  1H9O A;  2YU7 A;  1O4K A;  3TKZ A;  1JYU A;  1O4E A;  2FO0 A;  4K2R A;  4U17 A;  4LUD A;  3PSK A;  4EY0 A;  1NRV A;  1BG1 A;  2RSY A;  2SHP A;  1O49 A;  3UF4 A;  3VRZ A;  2ETZ A;  1JYR A;  5D0J A;  1FHS A;  1IS0 A;  2L4K A;  3T04 A;  1LCK A;  1BF5 A;  5DC0 B;  2HDX A;  4OHI A;  1QG1 E;  3GXX A;  1M27 A;  4OHH A;  4XZ0 A;  3VS3 A;  2EO3 A;  3VRR A;  2QMS A;  1WQU A;  3PSJ A;  4K45 A;  1X0N A;  1MW4 A;  1O4P A;  4XZ1 A;  1RJA A;  1Z3K A;  4OHE A;  1BLK A;  1LKK A;  4WWQ A;  3IN8 A;  2MC1 A;  4OHL A;  1O47 A;  1SHB A;  4DGX A;  4A4B A;  1AYD A;  2DLZ A;  3OB2 B;  5DC4 A;  4F59 A;  2K79 B;  3K2M A;  2GE9 A;  1BHF A;  3NHN A;  1A1C A;  2L6K A;  3CD3 A;  2B3O A;  2IUH A;  1GHU A;  1O4J A;  2AOA A;  1CSY A;  1FMK A;  1O42 A;  1FU6 A;  5IBS A;  2MQI A;  1O46 A;  2H46 E;  1AOT F;  2Y1N A;  1O4M A;  4TZI A;  3BUM B;  3BKB A;  4LUE A;  1O4I A;  3GQI B;  2EOB A;  2ABL A;  2IUI A;  4H1O A;  3PJP A;  3VGO A;  3US4 A;  1A09 A;  1QAD A;  2MRK A;  2YSX A;  3CXL A;  1BHH A;  1O4O A;  1O41 A;  1A07 A;  4K44 A;  2KK6 A;  1SPS A;  3BUW B;  4DGP A;  3S9K A;  2HUW A;  1FYR A;  5J3X A;  3CWG A;  3VRY A;  1OPK A;  1MIL A;  1R1Q A;  2EYZ A;  1BKL A;  1LUK A;  4M4Z A;  2AUG A;  1CWD L;  2CI9 A;  2IUG A;  4E68 A;  5IBM A;  3MXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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