4K44A

Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
104
structure length
104
Chain Sequence
SQAESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Rattus norvegicus
publication title Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
pubmed doi rcsb
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
total genus 24
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2013-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4k44A00
5DC0B 2EKXA 3TKZA 3WA4A 1SPSA 1BF5A 1M27A 1R1PA 1MW4A 1R1SA 1Y57A 2SHPA 1O48A 4FL3A 3S8NA 2Y1MA 2PTKA 1KA6A 2L3TA 2K7AB 3VROA 3UYOA 2ECDA 3K2MA 2FCIA 2LQWA 3VS1A 2XP1A 1JWOA 1O41A 1M61A 4K44A 3OP0A 1BKMA 3CXLA 1LUIA 2MC1A 5EHRA 3CWGA 2L4KA 3M7FA 2H5KA 3VS0A 2OQ1A 2CIAA 2HCKA 1FU5A 2ETZA 3VRQA 2HDVA 1Y1UA 2B3OA 3VRZA 1O47A 4E68A 5DF6A 2CI9A 1OPKA 2HDXA 1O49A 5BO4A 2EYVA 1NRVA 2AUGA 3S8OA 5IBSA 4P9ZA 2EL8A 3PFVA 2YSXA 1BM2A 3T04A 1AYDA 2KK6A 1FYRA 3VS2A 5D0JA 1X0NA 1O4JA 3VRPA 1RJAA 1IS0A 1HCSB 2JYQA 1Z3KA 1AYAA 3VRYA 1O4RA 3IN8A 1BLKA 2L6KA 1AYBA 2DM0A 2LNWA 1FHSA 1BG1A 2MQIA 5I6VA 3KFJA 3BUXB 1LUKA 3IN7A 5EG3B 2HMHA 3EACA 5DC9A 2H46E 1JU5A 5AULA 3VS6A 1P13A 3VS3A 4WWQA 3HIZB 1LUMA 4OHEA 5J3XA 1TZEE 1GHUA 2EOBA 2LQNA 2OZOA 4L1BB 2EYYA 3OB1B 1O4LA 3VGOA 3MAZA 2C0TA 1X6CA 2IUGA 1I3ZA 3GXXA 4NWGA 1D4TA 4H34A 2ABLA 1A1EA 1O4AA 3IMJA 1O4OA 4JEGA 4XZ0A 1O4KA 2KNOA 4K2RA 1O45A 2EU0A 1RQQC 1R1QA 1SPRA 1WQUA 1AB2A 1CSZA 3VS5A 2AOAA 1FMKA 2H8HA 1O46A 1A07A 2RORA 3MXYA 4TZIA 1XA6A 1MILA 4FBNA 3PS5A 4EIHA 5EHPA 1BFJA 1O4GA 1JYQA 1KA7A 1LKLA 2K79B 2C9WA 1BHHA 2YU7A 4F5AA 1UURA 2FO0A 2Y3AB 3OV1A 2DLYA 1F1WA 4OHHA 1A81A 3GQIB 3N84A 2DX0A 1A1AA 1OPLA 3BUWB 3N7YA 1SHAA 1A1BA 4X6SA 5GJHA 3BUMB 1TCEA 2AOBA 3TL0A 2IUIA 4GPLB 2EYZA 2DLZA 1AOUF 3VS4A 2RVFA 3PSKA 5CDWA 1KC2A 4JE4A 3NHNA 3BKBA 1SHDA 3QWXX 1O4DA 3S8LA 1K9AA 2DCRA 1O4FA 4GL9E 1IJRA 1LKKA 3UF4A 4F5BA 1O4MA 4M4ZA 3IMDA 3PJPA 2LNXA 1SHBA 2PLEA 4OHIA 1D4WA 2VIFA 2QMSA 5DC4A 2C0IA 3US4A 3VS7A 2CS0A 1BHFA 1AD5A 1X27A 1KSWA 1RPYA 4GWFA 5AXIA 3HHMB 1SKJA 4H1OA 1YVLA 2DVJA 1LCJA 1BKLA 4E93A 1O42A 3CD3A 2CBLA 1A09A 1O4EA 5EEQA 1CWEA 4DGXA 4EY0A 1O4NA 5EELA 5HKYA 1FBVA 4ROJA 2PNBA 4OHLA 2MRJA 1OO4A 1B47A 2SRCA 4DGPA 5HKWA 4A4BA 2HUWA 4K11A 3HCKA 1QCFA 4P9VA 1AYCA 1O4HA 1FBZA 1G83A 5HKZA 3EAZA 2GSBA 2BBUA 1YVHA 1QADA 1CSYA 2LCTA 1UUSA 3CBLA 4LUEA 1BFIA 4U17A 2IUHA 4OHDA 3S9KA 4NWFA 3VRRA 3C7IA 5IBMA 1CWDL 3OB2B 1BLJA 1A1CA 1GRIA 1O4CA 3BUOB 2EO6A 1O4QA 4K45A 1PICA 2CI8A 2Y1NA 2IZVA 4D8KA 1NZLA 1BMBA 3GXWA 3ZNIA 2PNAA 1O4BA 1F2FA 2RMXA 3QWYA 5KAZA 3BUNB 2CRHA 4JGHA 1HCTB 1D1ZA 1AOTF 2CR4A 1A08A 4QSYA 1OO3A 5GJIA 1NZVA 4U1PA 1LCKA 2PLDA 3N8MA 3OVEA 4F59A 1O44A 1O4PA 1CJ1A 1JYRA 1BHHB 2GE9A 1H9OA 2MRKA 3MXCA 2EO3A 1LUNA 1ZFPE 4LUDA 3VRNA 3PSJA 1O4IA 4A4CA 2RSYA 1O43A 1QG1E 2C0OA 2MK2A 3PQZA 1FU6A 3PLFB 4XZ1A 1JYUA 4FL2A
chains in the Genus database with same CATH superfamily
5DC0B 2EKXA 3TKZA 3WA4A 1SPSA 1BF5A 1M27A 1R1PA 1MW4A 1R1SA 1Y57A 2SHPA 1O48A 4FL3A 3S8NA 2Y1MA 2PTKA 1KA6A 2L3TA 2K7AB 3VROA 3UYOA 2ECDA 3K2MA 2FCIA 2LQWA 2LRAA 3VS1A 2XP1A 1JWOA 1O41A 1M61A 4K44A 3K2TA 3OP0A 1BKMA 3CXLA 1LUIA 2MC1A 5EHRA 3CWGA 2L4KA 3M7FA 2H5KA 3VS0A 2OQ1A 2CIAA 2HCKA 1FU5A 2ETZA 3VRQA 2HDVA 1Y1UA 2B3OA 3LYVA 3VRZA 1O47A 4E68A 5DF6A 2CI9A 1OPKA 2HDXA 1O49A 5BO4A 2EYVA 1NRVA 2AUGA 3S8OA 5IBSA 4P9ZA 2EL8A 3PFVA 2YSXA 1BM2A 3T04A 1AYDA 2KK6A 1FYRA 3VS2A 5D0JA 1X0NA 1O4JA 3VRPA 1RJAA 1IS0A 1HCSB 2JYQA 1Z3KA 1AYAA 3VRYA 1O4RA 3IN8A 1BLKA 2L6KA 1AYBA 2DM0A 2LNWA 1FHSA 1BG1A 2MQIA 5I6VA 3KFJA 2KGYA 3BUXB 1LUKA 3IN7A 5EG3B 2HMHA 3EACA 5DC9A 2H46E 1JU5A 5AULA 3VS6A 1P13A 3VS3A 4WWQA 3HIZB 1LUMA 4OHEA 5J3XA 1TZEE 1GHUA 2EOBA 2LQNA 2OZOA 4L1BB 2EYYA 3OB1B 1O4LA 3VGOA 3MAZA 2C0TA 1X6CA 2IUGA 1I3ZA 3GXXA 4NWGA 1D4TA 4H34A 2ABLA 1A1EA 1O4AA 3IMJA 1O4OA 4JEGA 4XZ0A 1O4KA 2KNOA 4K2RA 1O45A 2EU0A 1RQQC 1R1QA 1SPRA 1WQUA 1AB2A 1CSZA 3VS5A 2AOAA 1FMKA 2H8HA 1O46A 1A07A 2RORA 3MXYA 4TZIA 1XA6A 1MILA 4FBNA 3PS5A 4EIHA 5EHPA 1BFJA 1O4GA 1JYQA 1KA7A 1LKLA 2K79B 2C9WA 1BHHA 2YU7A 4F5AA 1UURA 2FO0A 2Y3AB 3OV1A 2DLYA 1F1WA 4OHHA 1A81A 3GQIB 3N84A 2DX0A 1A1AA 1OPLA 3BUWB 3N7YA 1SHAA 1A1BA 4X6SA 5GJHA 3BUMB 1TCEA 2AOBA 3TL0A 2IUIA 4GPLB 2EYZA 2DLZA 1AOUF 3VS4A 2RVFA 3PSKA 5CDWA 1KC2A 4JE4A 3NHNA 3BKBA 1SHDA 3QWXX 1O4DA 3S8LA 1K9AA 2DCRA 1O4FA 4GL9E 1IJRA 1LKKA 3UF4A 4F5BA 1O4MA 4M4ZA 3IMDA 3PJPA 2LNXA 1SHBA 2PLEA 4OHIA 1D4WA 2VIFA 2QMSA 5DC4A 2C0IA 3US4A 3VS7A 2CS0A 1BHFA 1AD5A 1X27A 1KSWA 1RPYA 4GWFA 5AXIA 3HHMB 1SKJA 4H1OA 1YVLA 2DVJA 1LCJA 1BKLA 4E93A 1O42A 3CD3A 2CBLA 1A09A 1O4EA 5EEQA 1CWEA 4DGXA 4EY0A 1O4NA 5EELA 5HKYA 1FBVA 4ROJA 2PNBA 4OHLA 2MRJA 1OO4A 1B47A 2SRCA 4DGPA 5HKWA 4A4BA 2HUWA 4K11A 3HCKA 1QCFA 4P9VA 1AYCA 1O4HA 1FBZA 1G83A 5HKZA 3EAZA 2GSBA 2BBUA 1YVHA 1QADA 1CSYA 2LCTA 1UUSA 3CBLA 4LUEA 1BFIA 4U17A 2IUHA 4OHDA 3S9KA 4NWFA 3VRRA 3C7IA 5IBMA 1CWDL 3OB2B 1BLJA 1A1CA 1GRIA 1O4CA 3BUOB 2EO6A 1O4QA 4K45A 1PICA 2CI8A 2Y1NA 2IZVA 4D8KA 1NZLA 1BMBA 3GXWA 3ZNIA 2PNAA 1O4BA 1F2FA 2RMXA 3QWYA 5KAZA 3BUNB 2CRHA 4JGHA 1HCTB 1D1ZA 1AOTF 2CR4A 1A08A 4QSYA 1OO3A 5GJIA 1NZVA 4U1PA 1LCKA 2PLDA 3N8MA 3OVEA 4F59A 1O44A 1O4PA 1CJ1A 1JYRA 1BHHB 2GE9A 1H9OA 2MRKA 3MXCA 2EO3A 1LUNA 1ZFPE 4LUDA 3VRNA 3PSJA 1O4IA 4A4CA 2RSYA 1O43A 1QG1E 2C0OA 2MK2A 3PQZA 1FU6A 3PLFB 4XZ1A 1JYUA 4FL2A
chains in the Genus database with same CATH topology
5DC0B 2EKXA 3TKZA 3WA4A 1SPSA 1BF5A 1M27A 1R1PA 1MW4A 1R1SA 1Y57A 2SHPA 1O48A 4FL3A 3S8NA 2Y1MA 2PTKA 1KA6A 2L3TA 2K7AB 3VROA 3UYOA 2ECDA 3K2MA 2FCIA 2LQWA 3VS1A 2XP1A 1JWOA 1O41A 1M61A 4K44A 3OP0A 1BKMA 3CXLA 1LUIA 2MC1A 5EHRA 3CWGA 2L4KA 3M7FA 2H5KA 3VS0A 2OQ1A 2CIAA 2HCKA 1FU5A 2ETZA 3VRQA 2HDVA 1Y1UA 2B3OA 3VRZA 1O47A 4E68A 5DF6A 2CI9A 1OPKA 2HDXA 1O49A 5BO4A 2EYVA 1NRVA 2AUGA 3S8OA 5IBSA 4P9ZA 2EL8A 3PFVA 2YSXA 1BM2A 3T04A 1AYDA 2KK6A 1FYRA 3VS2A 5D0JA 1X0NA 1O4JA 3VRPA 1RJAA 1IS0A 1HCSB 2JYQA 1Z3KA 1AYAA 3VRYA 1O4RA 3IN8A 1BLKA 2L6KA 1AYBA 2DM0A 2LNWA 1FHSA 1BG1A 2MQIA 5I6VA 3KFJA 3BUXB 1LUKA 3IN7A 5EG3B 2HMHA 3EACA 5DC9A 2H46E 1JU5A 5AULA 3VS6A 1P13A 3VS3A 4WWQA 3HIZB 1LUMA 4OHEA 5J3XA 1TZEE 1GHUA 2EOBA 2LQNA 2OZOA 4L1BB 2EYYA 3OB1B 1O4LA 3VGOA 3MAZA 2C0TA 1X6CA 2IUGA 1I3ZA 3GXXA 4NWGA 1D4TA 4H34A 2ABLA 1A1EA 1O4AA 3IMJA 1O4OA 4JEGA 4XZ0A 1O4KA 2KNOA 4K2RA 1O45A 2EU0A 1RQQC 1R1QA 1SPRA 1WQUA 1AB2A 1CSZA 3VS5A 2AOAA 1FMKA 2H8HA 1O46A 1A07A 2RORA 3MXYA 4TZIA 1XA6A 1MILA 4FBNA 3PS5A 4EIHA 5EHPA 1BFJA 1O4GA 1JYQA 1KA7A 1LKLA 2K79B 2C9WA 1BHHA 2YU7A 4F5AA 1UURA 2FO0A 2Y3AB 3OV1A 2DLYA 1F1WA 4OHHA 1A81A 3GQIB 3N84A 2DX0A 1A1AA 1OPLA 3BUWB 3N7YA 1SHAA 1A1BA 4X6SA 5GJHA 3BUMB 1TCEA 2AOBA 3TL0A 2IUIA 4GPLB 2EYZA 2DLZA 1AOUF 3VS4A 2RVFA 3PSKA 5CDWA 1KC2A 4JE4A 3NHNA 3BKBA 1SHDA 3QWXX 1O4DA 3S8LA 1K9AA 2DCRA 1O4FA 4GL9E 1IJRA 1LKKA 3UF4A 4F5BA 1O4MA 4M4ZA 3IMDA 3PJPA 2LNXA 1SHBA 2PLEA 4OHIA 1D4WA 2VIFA 2QMSA 5DC4A 2C0IA 3US4A 3VS7A 2CS0A 1BHFA 1AD5A 1X27A 1KSWA 1RPYA 4GWFA 5AXIA 3HHMB 1SKJA 4H1OA 1YVLA 2DVJA 1LCJA 1BKLA 4E93A 1O42A 3CD3A 2CBLA 1A09A 1O4EA 5EEQA 1CWEA 4DGXA 4EY0A 1O4NA 5EELA 5HKYA 1FBVA 4ROJA 2PNBA 4OHLA 2MRJA 1OO4A 1B47A 2SRCA 4DGPA 5HKWA 4A4BA 2HUWA 4K11A 3HCKA 1QCFA 4P9VA 1AYCA 1O4HA 1FBZA 1G83A 5HKZA 3EAZA 2GSBA 2BBUA 1YVHA 1QADA 1CSYA 2LCTA 1UUSA 3CBLA 4LUEA 1BFIA 4U17A 2IUHA 4OHDA 3S9KA 4NWFA 3VRRA 3C7IA 5IBMA 1CWDL 3OB2B 1BLJA 1A1CA 1GRIA 1O4CA 3BUOB 2EO6A 1O4QA 4K45A 1PICA 2CI8A 2Y1NA 2IZVA 4D8KA 1NZLA 1BMBA 3GXWA 3ZNIA 2PNAA 1O4BA 1F2FA 2RMXA 3QWYA 5KAZA 3BUNB 2CRHA 4JGHA 1HCTB 1D1ZA 1AOTF 2CR4A 1A08A 4QSYA 1OO3A 5GJIA 1NZVA 4U1PA 1LCKA 2PLDA 3N8MA 3OVEA 4F59A 1O44A 1O4PA 1CJ1A 1JYRA 1BHHB 2GE9A 1H9OA 2MRKA 3MXCA 2EO3A 1LUNA 1ZFPE 4LUDA 3VRNA 3PSJA 1O4IA 4A4CA 2RSYA 1O43A 1QG1E 2C0OA 2MK2A 3PQZA 1FU6A 3PLFB 4XZ1A 1JYUA 4FL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DC0 B;  2EKX A;  3TKZ A;  3WA4 A;  1SPS A;  1BF5 A;  1M27 A;  1R1P A;  1MW4 A;  1R1S A;  1Y57 A;  2SHP A;  1O48 A;  4FL3 A;  3S8N A;  2Y1M A;  2PTK A;  1KA6 A;  2L3T A;  2K7A B;  3VRO A;  3UYO A;  2ECD A;  3K2M A;  2FCI A;  2LQW A;  3VS1 A;  2XP1 A;  1JWO A;  1O41 A;  1M61 A;  4K44 A;  3OP0 A;  1BKM A;  3CXL A;  1LUI A;  2MC1 A;  5EHR A;  3CWG A;  2L4K A;  3M7F A;  2H5K A;  3VS0 A;  2OQ1 A;  2CIA A;  2HCK A;  1FU5 A;  2ETZ A;  3VRQ A;  2HDV A;  1Y1U A;  2B3O A;  3VRZ A;  1O47 A;  4E68 A;  5DF6 A;  2CI9 A;  1OPK A;  2HDX A;  1O49 A;  5BO4 A;  2EYV A;  1NRV A;  2AUG A;  3S8O A;  5IBS A;  4P9Z A;  2EL8 A;  3PFV A;  2YSX A;  1BM2 A;  3T04 A;  1AYD A;  2KK6 A;  1FYR A;  3VS2 A;  5D0J A;  1X0N A;  1O4J A;  3VRP A;  1RJA A;  1IS0 A;  1HCS B;  2JYQ A;  1Z3K A;  1AYA A;  3VRY A;  1O4R A;  3IN8 A;  1BLK A;  2L6K A;  1AYB A;  2DM0 A;  2LNW A;  1FHS A;  1BG1 A;  2MQI A;  5I6V A;  3KFJ A;  3BUX B;  1LUK A;  3IN7 A;  5EG3 B;  2HMH A;  3EAC A;  5DC9 A;  2H46 E;  1JU5 A;  5AUL A;  3VS6 A;  1P13 A;  3VS3 A;  4WWQ A;  3HIZ B;  1LUM A;  4OHE A;  5J3X A;  1TZE E;  1GHU A;  2EOB A;  2LQN A;  2OZO A;  4L1B B;  2EYY A;  3OB1 B;  1O4L A;  3VGO A;  3MAZ A;  2C0T A;  1X6C A;  2IUG A;  1I3Z A;  3GXX A;  4NWG A;  1D4T A;  4H34 A;  2ABL A;  1A1E A;  1O4A A;  3IMJ A;  1O4O A;  4JEG A;  4XZ0 A;  1O4K A;  2KNO A;  4K2R A;  1O45 A;  2EU0 A;  1RQQ C;  1R1Q A;  1SPR A;  1WQU A;  1AB2 A;  1CSZ A;  3VS5 A;  2AOA A;  1FMK A;  2H8H A;  1O46 A;  1A07 A;  2ROR A;  3MXY A;  4TZI A;  1XA6 A;  1MIL A;  4FBN A;  3PS5 A;  4EIH A;  5EHP A;  1BFJ A;  1O4G A;  1JYQ A;  1KA7 A;  1LKL A;  2K79 B;  2C9W A;  1BHH A;  2YU7 A;  4F5A A;  1UUR A;  2FO0 A;  2Y3A B;  3OV1 A;  2DLY A;  1F1W A;  4OHH A;  1A81 A;  3GQI B;  3N84 A;  2DX0 A;  1A1A A;  1OPL A;  3BUW B;  3N7Y A;  1SHA A;  1A1B A;  4X6S A;  5GJH A;  3BUM B;  1TCE A;  2AOB A;  3TL0 A;  2IUI A;  4GPL B;  2EYZ A;  2DLZ A;  1AOU F;  3VS4 A;  2RVF A;  3PSK A;  5CDW A;  1KC2 A;  4JE4 A;  3NHN A;  3BKB A;  1SHD A;  3QWX X;  1O4D A;  3S8L A;  1K9A A;  2DCR A;  1O4F A;  4GL9 E;  1IJR A;  1LKK A;  3UF4 A;  4F5B A;  1O4M A;  4M4Z A;  3IMD A;  3PJP A;  2LNX A;  1SHB A;  2PLE A;  4OHI A;  1D4W A;  2VIF A;  2QMS A;  5DC4 A;  2C0I A;  3US4 A;  3VS7 A;  2CS0 A;  1BHF A;  1AD5 A;  1X27 A;  1KSW A;  1RPY A;  4GWF A;  5AXI A;  3HHM B;  1SKJ A;  4H1O A;  1YVL A;  2DVJ A;  1LCJ A;  1BKL A;  4E93 A;  1O42 A;  3CD3 A;  2CBL A;  1A09 A;  1O4E A;  5EEQ A;  1CWE A;  4DGX A;  4EY0 A;  1O4N A;  5EEL A;  5HKY A;  1FBV A;  4ROJ A;  2PNB A;  4OHL A;  2MRJ A;  1OO4 A;  1B47 A;  2SRC A;  4DGP A;  5HKW A;  4A4B A;  2HUW A;  4K11 A;  3HCK A;  1QCF A;  4P9V A;  1AYC A;  1O4H A;  1FBZ A;  1G83 A;  5HKZ A;  3EAZ A;  2GSB A;  2BBU A;  1YVH A;  1QAD A;  1CSY A;  2LCT A;  1UUS A;  3CBL A;  4LUE A;  1BFI A;  4U17 A;  2IUH A;  4OHD A;  3S9K A;  4NWF A;  3VRR A;  3C7I A;  5IBM A;  1CWD L;  3OB2 B;  1BLJ A;  1A1C A;  1GRI A;  1O4C A;  3BUO B;  2EO6 A;  1O4Q A;  4K45 A;  1PIC A;  2CI8 A;  2Y1N A;  2IZV A;  4D8K A;  1NZL A;  1BMB A;  3GXW A;  3ZNI A;  2PNA A;  1O4B A;  1F2F A;  2RMX A;  3QWY A;  5KAZ A;  3BUN B;  2CRH A;  4JGH A;  1HCT B;  1D1Z A;  1AOT F;  2CR4 A;  1A08 A;  4QSY A;  1OO3 A;  5GJI A;  1NZV A;  4U1P A;  1LCK A;  2PLD A;  3N8M A;  3OVE A;  4F59 A;  1O44 A;  1O4P A;  1CJ1 A;  1JYR A;  1BHH B;  2GE9 A;  1H9O A;  2MRK A;  3MXC A;  2EO3 A;  1LUN A;  1ZFP E;  4LUD A;  3VRN A;  3PSJ A;  1O4I A;  4A4C A;  2RSY A;  1O43 A;  1QG1 E;  2C0O A;  2MK2 A;  3PQZ A;  1FU6 A;  3PLF B;  4XZ1 A;  1JYU A;  4FL2 A; 
#chains in the Genus database with same CATH topology
 5DC0 B;  2EKX A;  3TKZ A;  3WA4 A;  1SPS A;  1BF5 A;  1M27 A;  1R1P A;  1MW4 A;  1R1S A;  1Y57 A;  2SHP A;  1O48 A;  4FL3 A;  3S8N A;  2Y1M A;  2PTK A;  1KA6 A;  2L3T A;  2K7A B;  3VRO A;  3UYO A;  2ECD A;  3K2M A;  2FCI A;  2LQW A;  2LRA A;  3VS1 A;  2XP1 A;  1JWO A;  1O41 A;  1M61 A;  4K44 A;  3K2T A;  3OP0 A;  1BKM A;  3CXL A;  1LUI A;  2MC1 A;  5EHR A;  3CWG A;  2L4K A;  3M7F A;  2H5K A;  3VS0 A;  2OQ1 A;  2CIA A;  2HCK A;  1FU5 A;  2ETZ A;  3VRQ A;  2HDV A;  1Y1U A;  2B3O A;  3LYV A;  3VRZ A;  1O47 A;  4E68 A;  5DF6 A;  2CI9 A;  1OPK A;  2HDX A;  1O49 A;  5BO4 A;  2EYV A;  1NRV A;  2AUG A;  3S8O A;  5IBS A;  4P9Z A;  2EL8 A;  3PFV A;  2YSX A;  1BM2 A;  3T04 A;  1AYD A;  2KK6 A;  1FYR A;  3VS2 A;  5D0J A;  1X0N A;  1O4J A;  3VRP A;  1RJA A;  1IS0 A;  1HCS B;  2JYQ A;  1Z3K A;  1AYA A;  3VRY A;  1O4R A;  3IN8 A;  1BLK A;  2L6K A;  1AYB A;  2DM0 A;  2LNW A;  1FHS A;  1BG1 A;  2MQI A;  5I6V A;  3KFJ A;  2KGY A;  3BUX B;  1LUK A;  3IN7 A;  5EG3 B;  2HMH A;  3EAC A;  5DC9 A;  2H46 E;  1JU5 A;  5AUL A;  3VS6 A;  1P13 A;  3VS3 A;  4WWQ A;  3HIZ B;  1LUM A;  4OHE A;  5J3X A;  1TZE E;  1GHU A;  2EOB A;  2LQN A;  2OZO A;  4L1B B;  2EYY A;  3OB1 B;  1O4L A;  3VGO A;  3MAZ A;  2C0T A;  1X6C A;  2IUG A;  1I3Z A;  3GXX A;  4NWG A;  1D4T A;  4H34 A;  2ABL A;  1A1E A;  1O4A A;  3IMJ A;  1O4O A;  4JEG A;  4XZ0 A;  1O4K A;  2KNO A;  4K2R A;  1O45 A;  2EU0 A;  1RQQ C;  1R1Q A;  1SPR A;  1WQU A;  1AB2 A;  1CSZ A;  3VS5 A;  2AOA A;  1FMK A;  2H8H A;  1O46 A;  1A07 A;  2ROR A;  3MXY A;  4TZI A;  1XA6 A;  1MIL A;  4FBN A;  3PS5 A;  4EIH A;  5EHP A;  1BFJ A;  1O4G A;  1JYQ A;  1KA7 A;  1LKL A;  2K79 B;  2C9W A;  1BHH A;  2YU7 A;  4F5A A;  1UUR A;  2FO0 A;  2Y3A B;  3OV1 A;  2DLY A;  1F1W A;  4OHH A;  1A81 A;  3GQI B;  3N84 A;  2DX0 A;  1A1A A;  1OPL A;  3BUW B;  3N7Y A;  1SHA A;  1A1B A;  4X6S A;  5GJH A;  3BUM B;  1TCE A;  2AOB A;  3TL0 A;  2IUI A;  4GPL B;  2EYZ A;  2DLZ A;  1AOU F;  3VS4 A;  2RVF A;  3PSK A;  5CDW A;  1KC2 A;  4JE4 A;  3NHN A;  3BKB A;  1SHD A;  3QWX X;  1O4D A;  3S8L A;  1K9A A;  2DCR A;  1O4F A;  4GL9 E;  1IJR A;  1LKK A;  3UF4 A;  4F5B A;  1O4M A;  4M4Z A;  3IMD A;  3PJP A;  2LNX A;  1SHB A;  2PLE A;  4OHI A;  1D4W A;  2VIF A;  2QMS A;  5DC4 A;  2C0I A;  3US4 A;  3VS7 A;  2CS0 A;  1BHF A;  1AD5 A;  1X27 A;  1KSW A;  1RPY A;  4GWF A;  5AXI A;  3HHM B;  1SKJ A;  4H1O A;  1YVL A;  2DVJ A;  1LCJ A;  1BKL A;  4E93 A;  1O42 A;  3CD3 A;  2CBL A;  1A09 A;  1O4E A;  5EEQ A;  1CWE A;  4DGX A;  4EY0 A;  1O4N A;  5EEL A;  5HKY A;  1FBV A;  4ROJ A;  2PNB A;  4OHL A;  2MRJ A;  1OO4 A;  1B47 A;  2SRC A;  4DGP A;  5HKW A;  4A4B A;  2HUW A;  4K11 A;  3HCK A;  1QCF A;  4P9V A;  1AYC A;  1O4H A;  1FBZ A;  1G83 A;  5HKZ A;  3EAZ A;  2GSB A;  2BBU A;  1YVH A;  1QAD A;  1CSY A;  2LCT A;  1UUS A;  3CBL A;  4LUE A;  1BFI A;  4U17 A;  2IUH A;  4OHD A;  3S9K A;  4NWF A;  3VRR A;  3C7I A;  5IBM A;  1CWD L;  3OB2 B;  1BLJ A;  1A1C A;  1GRI A;  1O4C A;  3BUO B;  2EO6 A;  1O4Q A;  4K45 A;  1PIC A;  2CI8 A;  2Y1N A;  2IZV A;  4D8K A;  1NZL A;  1BMB A;  3GXW A;  3ZNI A;  2PNA A;  1O4B A;  1F2F A;  2RMX A;  3QWY A;  5KAZ A;  3BUN B;  2CRH A;  4JGH A;  1HCT B;  1D1Z A;  1AOT F;  2CR4 A;  1A08 A;  4QSY A;  1OO3 A;  5GJI A;  1NZV A;  4U1P A;  1LCK A;  2PLD A;  3N8M A;  3OVE A;  4F59 A;  1O44 A;  1O4P A;  1CJ1 A;  1JYR A;  1BHH B;  2GE9 A;  1H9O A;  2MRK A;  3MXC A;  2EO3 A;  1LUN A;  1ZFP E;  4LUD A;  3VRN A;  3PSJ A;  1O4I A;  4A4C A;  2RSY A;  1O43 A;  1QG1 E;  2C0O A;  2MK2 A;  3PQZ A;  1FU6 A;  3PLF B;  4XZ1 A;  1JYU A;  4FL2 A; 
#chains in the Genus database with same CATH homology
 5DC0 B;  2EKX A;  3TKZ A;  3WA4 A;  1SPS A;  1BF5 A;  1M27 A;  1R1P A;  1MW4 A;  1R1S A;  1Y57 A;  2SHP A;  1O48 A;  4FL3 A;  3S8N A;  2Y1M A;  2PTK A;  1KA6 A;  2L3T A;  2K7A B;  3VRO A;  3UYO A;  2ECD A;  3K2M A;  2FCI A;  2LQW A;  3VS1 A;  2XP1 A;  1JWO A;  1O41 A;  1M61 A;  4K44 A;  3OP0 A;  1BKM A;  3CXL A;  1LUI A;  2MC1 A;  5EHR A;  3CWG A;  2L4K A;  3M7F A;  2H5K A;  3VS0 A;  2OQ1 A;  2CIA A;  2HCK A;  1FU5 A;  2ETZ A;  3VRQ A;  2HDV A;  1Y1U A;  2B3O A;  3VRZ A;  1O47 A;  4E68 A;  5DF6 A;  2CI9 A;  1OPK A;  2HDX A;  1O49 A;  5BO4 A;  2EYV A;  1NRV A;  2AUG A;  3S8O A;  5IBS A;  4P9Z A;  2EL8 A;  3PFV A;  2YSX A;  1BM2 A;  3T04 A;  1AYD A;  2KK6 A;  1FYR A;  3VS2 A;  5D0J A;  1X0N A;  1O4J A;  3VRP A;  1RJA A;  1IS0 A;  1HCS B;  2JYQ A;  1Z3K A;  1AYA A;  3VRY A;  1O4R A;  3IN8 A;  1BLK A;  2L6K A;  1AYB A;  2DM0 A;  2LNW A;  1FHS A;  1BG1 A;  2MQI A;  5I6V A;  3KFJ A;  3BUX B;  1LUK A;  3IN7 A;  5EG3 B;  2HMH A;  3EAC A;  5DC9 A;  2H46 E;  1JU5 A;  5AUL A;  3VS6 A;  1P13 A;  3VS3 A;  4WWQ A;  3HIZ B;  1LUM A;  4OHE A;  5J3X A;  1TZE E;  1GHU A;  2EOB A;  2LQN A;  2OZO A;  4L1B B;  2EYY A;  3OB1 B;  1O4L A;  3VGO A;  3MAZ A;  2C0T A;  1X6C A;  2IUG A;  1I3Z A;  3GXX A;  4NWG A;  1D4T A;  4H34 A;  2ABL A;  1A1E A;  1O4A A;  3IMJ A;  1O4O A;  4JEG A;  4XZ0 A;  1O4K A;  2KNO A;  4K2R A;  1O45 A;  2EU0 A;  1RQQ C;  1R1Q A;  1SPR A;  1WQU A;  1AB2 A;  1CSZ A;  3VS5 A;  2AOA A;  1FMK A;  2H8H A;  1O46 A;  1A07 A;  2ROR A;  3MXY A;  4TZI A;  1XA6 A;  1MIL A;  4FBN A;  3PS5 A;  4EIH A;  5EHP A;  1BFJ A;  1O4G A;  1JYQ A;  1KA7 A;  1LKL A;  2K79 B;  2C9W A;  1BHH A;  2YU7 A;  4F5A A;  1UUR A;  2FO0 A;  2Y3A B;  3OV1 A;  2DLY A;  1F1W A;  4OHH A;  1A81 A;  3GQI B;  3N84 A;  2DX0 A;  1A1A A;  1OPL A;  3BUW B;  3N7Y A;  1SHA A;  1A1B A;  4X6S A;  5GJH A;  3BUM B;  1TCE A;  2AOB A;  3TL0 A;  2IUI A;  4GPL B;  2EYZ A;  2DLZ A;  1AOU F;  3VS4 A;  2RVF A;  3PSK A;  5CDW A;  1KC2 A;  4JE4 A;  3NHN A;  3BKB A;  1SHD A;  3QWX X;  1O4D A;  3S8L A;  1K9A A;  2DCR A;  1O4F A;  4GL9 E;  1IJR A;  1LKK A;  3UF4 A;  4F5B A;  1O4M A;  4M4Z A;  3IMD A;  3PJP A;  2LNX A;  1SHB A;  2PLE A;  4OHI A;  1D4W A;  2VIF A;  2QMS A;  5DC4 A;  2C0I A;  3US4 A;  3VS7 A;  2CS0 A;  1BHF A;  1AD5 A;  1X27 A;  1KSW A;  1RPY A;  4GWF A;  5AXI A;  3HHM B;  1SKJ A;  4H1O A;  1YVL A;  2DVJ A;  1LCJ A;  1BKL A;  4E93 A;  1O42 A;  3CD3 A;  2CBL A;  1A09 A;  1O4E A;  5EEQ A;  1CWE A;  4DGX A;  4EY0 A;  1O4N A;  5EEL A;  5HKY A;  1FBV A;  4ROJ A;  2PNB A;  4OHL A;  2MRJ A;  1OO4 A;  1B47 A;  2SRC A;  4DGP A;  5HKW A;  4A4B A;  2HUW A;  4K11 A;  3HCK A;  1QCF A;  4P9V A;  1AYC A;  1O4H A;  1FBZ A;  1G83 A;  5HKZ A;  3EAZ A;  2GSB A;  2BBU A;  1YVH A;  1QAD A;  1CSY A;  2LCT A;  1UUS A;  3CBL A;  4LUE A;  1BFI A;  4U17 A;  2IUH A;  4OHD A;  3S9K A;  4NWF A;  3VRR A;  3C7I A;  5IBM A;  1CWD L;  3OB2 B;  1BLJ A;  1A1C A;  1GRI A;  1O4C A;  3BUO B;  2EO6 A;  1O4Q A;  4K45 A;  1PIC A;  2CI8 A;  2Y1N A;  2IZV A;  4D8K A;  1NZL A;  1BMB A;  3GXW A;  3ZNI A;  2PNA A;  1O4B A;  1F2F A;  2RMX A;  3QWY A;  5KAZ A;  3BUN B;  2CRH A;  4JGH A;  1HCT B;  1D1Z A;  1AOT F;  2CR4 A;  1A08 A;  4QSY A;  1OO3 A;  5GJI A;  1NZV A;  4U1P A;  1LCK A;  2PLD A;  3N8M A;  3OVE A;  4F59 A;  1O44 A;  1O4P A;  1CJ1 A;  1JYR A;  1BHH B;  2GE9 A;  1H9O A;  2MRK A;  3MXC A;  2EO3 A;  1LUN A;  1ZFP E;  4LUD A;  3VRN A;  3PSJ A;  1O4I A;  4A4C A;  2RSY A;  1O43 A;  1QG1 E;  2C0O A;  2MK2 A;  3PQZ A;  1FU6 A;  3PLF B;  4XZ1 A;  1JYU A;  4FL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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