4K45A

Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
QAESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
total genus 26
structure length 102
sequence length 102
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2013-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4k45A00
1FYRA 2BBUA 4JEGA 1BF5A 1RPYA 5DC0B 4XZ0A 4H1OA 1BHHB 2EOBA 2MC1A 2LNXA 1MW4A 4L1BB 2DLZA 3CD3A 1BFJA 2MRJA 1JYQA 4A4CA 2EKXA 1O4HA 1O4IA 2RSYA 3T04A 1B47A 5BO4A 3IMDA 2EU0A 1QG1E 2LQWA 3S8NA 1OPKA 4EIHA 3N8MA 1K9AA 1O4RA 1O4LA 1P13A 3BUMB 3PSJA 4EY0A 3VRRA 1O4PA 2CI8A 4TZIA 1FU5A 2K7AB 1KSWA 2SRCA 1KA7A 1M27A 1UUSA 2YSXA 1O4GA 1O4JA 4OHIA 2DX0A 3TKZA 5GJHA 5GJIA 5IBSA 1A1EA 3EAZA 4H34A 3BUOB 3QWXX 4JGHA 3VS3A 1A08A 3VS0A 4X6SA 3VS2A 5IBMA 2AUGA 4K44A 1CSZA 2EYYA 2PLDA 3BUXB 2RMXA 1LKLA 3OVEA 1O47A 1H9OA 1LUKA 1UURA 3N7YA 1O4FA 2IUIA 2PNAA 3PLFB 4FL2A 3VRZA 1WQUA 1LUNA 4NWGA 2CIAA 1O49A 5HKWA 4FL3A 1FBVA 5DC4A 4DGXA 1O4MA 4F5BA 3VRPA 3QWYA 3GXXA 3N84A 3US4A 1QADA 5DC9A 4NWFA 1CWEA 5KAZA 4FBNA 1AYCA 1FMKA 1SPRA 2ECDA 1OO3A 2LCTA 4K45A 4F59A 1A1AA 1XA6A 1SHAA 2IZVA 1AOTF 3OP0A 5AXIA 2CRHA 1IJRA 4ROJA 1BFIA 1NRVA 3UYOA 1GHUA 1A09A 4OHDA 3MXYA 1BKMA 1JYRA 2GE9A 1PICA 2PTKA 3VS4A 1SHBA 3C7IA 1F1WA 3PS5A 2EO3A 1YVLA 2GSBA 2L3TA 4GPLB 2DVJA 1O4AA 3IN7A 1D1ZA 1AYDA 1AOUF 2L6KA 3S8LA 3IMJA 5EEQA 1IS0A 1BHFA 3VS6A 4WWQA 1KC2A 2IUGA 2FO0A 2PNBA 2L4KA 2C0OA 1O4CA 3OB1B 1AD5A 1BLJA 2EO6A 2CR4A 3VRQA 2QMSA 1X27A 1ZFPE 2DLYA 1LCKA 1Z3KA 1I3ZA 1CSYA 1D4TA 1A07A 3MAZA 1O45A 1GRIA 2EYZA 3VS7A 1O4NA 2IUHA 1YVHA 3VS5A 1BG1A 2DM0A 4U17A 3WA4A 3PJPA 3GQIB 3MXCA 2H8HA 2AOBA 4DGPA 1O4DA 1OPLA 2ABLA 2VIFA 5D0JA 4LUDA 1O4EA 2B3OA 1SPSA 1X0NA 2DCRA 2MK2A 3TL0A 2PLEA 3BUWB 2K79B 1O4BA 2AOAA 4GL9E 1Y1UA 1A1BA 2C0IA 4E93A 2H46E 4P9ZA 1R1SA 2MRKA 2H5KA 1SHDA 1O43A 1O46A 3NHNA 4M4ZA 1O41A 2HUWA 1RQQC 4A4BA 5EELA 4OHLA 1D4WA 1G83A 4K11A 1R1PA 1NZLA 5I6VA 3S8OA 1M61A 5HKZA 1JYUA 4F5AA 2C0TA 3VROA 1SKJA 3M7FA 2LNWA 3HCKA 1LUMA 2FCIA 2JYQA 5EHPA 1LKKA 1CWDL 2HDVA 3VRYA 3IN8A 3OV1A 3PQZA 2YU7A 1O48A 4U1PA 2Y3AB 1O4QA 1JU5A 3HHMB 1BKLA 2CS0A 1TZEE 1HCTB 1O4OA 1LUIA 2OQ1A 1KA6A 1O4KA 3GXWA 2HCKA 4OHHA 4GWFA 4K2RA 1HCSB 1BLKA 4E68A 3BKBA 4XZ1A 3OB2B 2CBLA 3CBLA 1Y57A 3PFVA 3VRNA 1AYBA 2Y1NA 1BM2A 2ETZA 3CWGA 2RORA 4LUEA 1AYAA 1FHSA 5EG3B 3VS1A 1OO4A 5HKYA 3BUNB 2RVFA 2HMHA 3K2MA 2EYVA 2EL8A 3EACA 1BHHA 3PSKA 5DF6A 4QSYA 2XP1A 1F2FA 3S9KA 2OZOA 1CJ1A 1BMBA 1MILA 1FU6A 4JE4A 5EHRA 4D8KA 1QCFA 2HDXA 1A1CA 2KNOA 2KK6A 1AB2A 2C9WA 1FBZA 4OHEA 3HIZB 3KFJA 5J3XA 3UF4A 1R1QA 1O42A 3VGOA 1JWOA 1O44A 1LCJA 5AULA 2Y1MA 1A81A 3CXLA 1X6CA 2LQNA 1RJAA 1NZVA 3ZNIA 2SHPA 2MQIA 2CI9A 4P9VA 1TCEA 5CDWA
chains in the Genus database with same CATH superfamily
1FYRA 2BBUA 4JEGA 1BF5A 1RPYA 5DC0B 4XZ0A 4H1OA 1BHHB 2EOBA 2MC1A 2LNXA 1MW4A 4L1BB 2DLZA 3CD3A 1BFJA 2MRJA 1JYQA 4A4CA 2EKXA 1O4HA 1O4IA 2RSYA 3T04A 1B47A 2LRAA 5BO4A 3IMDA 2EU0A 1QG1E 2LQWA 3S8NA 1OPKA 4EIHA 3N8MA 1K9AA 1O4RA 3K2TA 1O4LA 1P13A 3BUMB 3PSJA 4EY0A 3VRRA 1O4PA 2CI8A 4TZIA 1FU5A 2K7AB 1KSWA 2SRCA 1KA7A 1M27A 1UUSA 2YSXA 1O4GA 1O4JA 4OHIA 2DX0A 3TKZA 5GJHA 5GJIA 5IBSA 1A1EA 3EAZA 4H34A 3BUOB 3QWXX 4JGHA 3VS3A 1A08A 3VS0A 4X6SA 3VS2A 5IBMA 2AUGA 4K44A 1CSZA 2EYYA 2PLDA 3BUXB 2RMXA 1LKLA 3OVEA 1O47A 1H9OA 1LUKA 1UURA 3N7YA 1O4FA 2IUIA 2PNAA 3PLFB 4FL2A 3VRZA 1WQUA 3LYVA 1LUNA 4NWGA 2CIAA 1O49A 5HKWA 4FL3A 1FBVA 5DC4A 4DGXA 1O4MA 4F5BA 3VRPA 3QWYA 3GXXA 3N84A 3US4A 2KGYA 1QADA 5DC9A 4NWFA 1CWEA 5KAZA 4FBNA 1AYCA 1FMKA 1SPRA 2ECDA 1OO3A 2LCTA 4K45A 4F59A 1A1AA 1XA6A 1SHAA 2IZVA 1AOTF 3OP0A 5AXIA 2CRHA 1IJRA 4ROJA 1BFIA 1NRVA 3UYOA 1GHUA 1A09A 4OHDA 3MXYA 1BKMA 1JYRA 2GE9A 1PICA 2PTKA 3VS4A 1SHBA 3C7IA 1F1WA 3PS5A 2EO3A 1YVLA 2GSBA 2L3TA 4GPLB 2DVJA 1O4AA 3IN7A 1D1ZA 1AYDA 1AOUF 2L6KA 3S8LA 3IMJA 5EEQA 1IS0A 1BHFA 3VS6A 4WWQA 1KC2A 2IUGA 2FO0A 2PNBA 2L4KA 2C0OA 1O4CA 3OB1B 1AD5A 1BLJA 2EO6A 2CR4A 3VRQA 2QMSA 1X27A 1ZFPE 2DLYA 1LCKA 1Z3KA 1I3ZA 1CSYA 1D4TA 1A07A 3MAZA 1O45A 1GRIA 2EYZA 3VS7A 1O4NA 2IUHA 1YVHA 3VS5A 1BG1A 2DM0A 4U17A 3WA4A 3PJPA 3GQIB 3MXCA 2H8HA 2AOBA 4DGPA 1O4DA 1OPLA 2ABLA 2VIFA 5D0JA 4LUDA 1O4EA 2B3OA 1SPSA 1X0NA 2DCRA 2MK2A 3TL0A 2PLEA 3BUWB 2K79B 1O4BA 2AOAA 4GL9E 1Y1UA 1A1BA 2C0IA 4E93A 2H46E 4P9ZA 1R1SA 2MRKA 2H5KA 1SHDA 1O43A 1O46A 3NHNA 4M4ZA 1O41A 2HUWA 1RQQC 4A4BA 5EELA 4OHLA 1D4WA 1G83A 4K11A 1R1PA 1NZLA 5I6VA 3S8OA 1M61A 5HKZA 1JYUA 4F5AA 2C0TA 3VROA 1SKJA 3M7FA 2LNWA 3HCKA 1LUMA 2FCIA 2JYQA 5EHPA 1LKKA 1CWDL 2HDVA 3VRYA 3IN8A 3OV1A 3PQZA 2YU7A 1O48A 4U1PA 2Y3AB 1O4QA 1JU5A 3HHMB 1BKLA 2CS0A 1TZEE 1HCTB 1O4OA 1LUIA 2OQ1A 1KA6A 1O4KA 3GXWA 2HCKA 4OHHA 4GWFA 4K2RA 1HCSB 1BLKA 4E68A 3BKBA 4XZ1A 3OB2B 2CBLA 3CBLA 1Y57A 3PFVA 3VRNA 1AYBA 2Y1NA 1BM2A 2ETZA 3CWGA 2RORA 4LUEA 1AYAA 1FHSA 5EG3B 3VS1A 1OO4A 5HKYA 3BUNB 2RVFA 2HMHA 3K2MA 2EYVA 2EL8A 3EACA 1BHHA 3PSKA 5DF6A 4QSYA 2XP1A 1F2FA 3S9KA 2OZOA 1CJ1A 1BMBA 1MILA 1FU6A 4JE4A 5EHRA 4D8KA 1QCFA 2HDXA 1A1CA 2KNOA 2KK6A 1AB2A 2C9WA 1FBZA 4OHEA 3HIZB 3KFJA 5J3XA 3UF4A 1R1QA 1O42A 3VGOA 1JWOA 1O44A 1LCJA 5AULA 2Y1MA 1A81A 3CXLA 1X6CA 2LQNA 1RJAA 1NZVA 3ZNIA 2SHPA 2MQIA 2CI9A 4P9VA 1TCEA 5CDWA
chains in the Genus database with same CATH topology
1FYRA 2BBUA 4JEGA 1BF5A 1RPYA 5DC0B 4XZ0A 4H1OA 1BHHB 2EOBA 2MC1A 2LNXA 1MW4A 4L1BB 2DLZA 3CD3A 1BFJA 2MRJA 1JYQA 4A4CA 2EKXA 1O4HA 1O4IA 2RSYA 3T04A 1B47A 5BO4A 3IMDA 2EU0A 1QG1E 2LQWA 3S8NA 1OPKA 4EIHA 3N8MA 1K9AA 1O4RA 1O4LA 1P13A 3BUMB 3PSJA 4EY0A 3VRRA 1O4PA 2CI8A 4TZIA 1FU5A 2K7AB 1KSWA 2SRCA 1KA7A 1M27A 1UUSA 2YSXA 1O4GA 1O4JA 4OHIA 2DX0A 3TKZA 5GJHA 5GJIA 5IBSA 1A1EA 3EAZA 4H34A 3BUOB 3QWXX 4JGHA 3VS3A 1A08A 3VS0A 4X6SA 3VS2A 5IBMA 2AUGA 4K44A 1CSZA 2EYYA 2PLDA 3BUXB 2RMXA 1LKLA 3OVEA 1O47A 1H9OA 1LUKA 1UURA 3N7YA 1O4FA 2IUIA 2PNAA 3PLFB 4FL2A 3VRZA 1WQUA 1LUNA 4NWGA 2CIAA 1O49A 5HKWA 4FL3A 1FBVA 5DC4A 4DGXA 1O4MA 4F5BA 3VRPA 3QWYA 3GXXA 3N84A 3US4A 1QADA 5DC9A 4NWFA 1CWEA 5KAZA 4FBNA 1AYCA 1FMKA 1SPRA 2ECDA 1OO3A 2LCTA 4K45A 4F59A 1A1AA 1XA6A 1SHAA 2IZVA 1AOTF 3OP0A 5AXIA 2CRHA 1IJRA 4ROJA 1BFIA 1NRVA 3UYOA 1GHUA 1A09A 4OHDA 3MXYA 1BKMA 1JYRA 2GE9A 1PICA 2PTKA 3VS4A 1SHBA 3C7IA 1F1WA 3PS5A 2EO3A 1YVLA 2GSBA 2L3TA 4GPLB 2DVJA 1O4AA 3IN7A 1D1ZA 1AYDA 1AOUF 2L6KA 3S8LA 3IMJA 5EEQA 1IS0A 1BHFA 3VS6A 4WWQA 1KC2A 2IUGA 2FO0A 2PNBA 2L4KA 2C0OA 1O4CA 3OB1B 1AD5A 1BLJA 2EO6A 2CR4A 3VRQA 2QMSA 1X27A 1ZFPE 2DLYA 1LCKA 1Z3KA 1I3ZA 1CSYA 1D4TA 1A07A 3MAZA 1O45A 1GRIA 2EYZA 3VS7A 1O4NA 2IUHA 1YVHA 3VS5A 1BG1A 2DM0A 4U17A 3WA4A 3PJPA 3GQIB 3MXCA 2H8HA 2AOBA 4DGPA 1O4DA 1OPLA 2ABLA 2VIFA 5D0JA 4LUDA 1O4EA 2B3OA 1SPSA 1X0NA 2DCRA 2MK2A 3TL0A 2PLEA 3BUWB 2K79B 1O4BA 2AOAA 4GL9E 1Y1UA 1A1BA 2C0IA 4E93A 2H46E 4P9ZA 1R1SA 2MRKA 2H5KA 1SHDA 1O43A 1O46A 3NHNA 4M4ZA 1O41A 2HUWA 1RQQC 4A4BA 5EELA 4OHLA 1D4WA 1G83A 4K11A 1R1PA 1NZLA 5I6VA 3S8OA 1M61A 5HKZA 1JYUA 4F5AA 2C0TA 3VROA 1SKJA 3M7FA 2LNWA 3HCKA 1LUMA 2FCIA 2JYQA 5EHPA 1LKKA 1CWDL 2HDVA 3VRYA 3IN8A 3OV1A 3PQZA 2YU7A 1O48A 4U1PA 2Y3AB 1O4QA 1JU5A 3HHMB 1BKLA 2CS0A 1TZEE 1HCTB 1O4OA 1LUIA 2OQ1A 1KA6A 1O4KA 3GXWA 2HCKA 4OHHA 4GWFA 4K2RA 1HCSB 1BLKA 4E68A 3BKBA 4XZ1A 3OB2B 2CBLA 3CBLA 1Y57A 3PFVA 3VRNA 1AYBA 2Y1NA 1BM2A 2ETZA 3CWGA 2RORA 4LUEA 1AYAA 1FHSA 5EG3B 3VS1A 1OO4A 5HKYA 3BUNB 2RVFA 2HMHA 3K2MA 2EYVA 2EL8A 3EACA 1BHHA 3PSKA 5DF6A 4QSYA 2XP1A 1F2FA 3S9KA 2OZOA 1CJ1A 1BMBA 1MILA 1FU6A 4JE4A 5EHRA 4D8KA 1QCFA 2HDXA 1A1CA 2KNOA 2KK6A 1AB2A 2C9WA 1FBZA 4OHEA 3HIZB 3KFJA 5J3XA 3UF4A 1R1QA 1O42A 3VGOA 1JWOA 1O44A 1LCJA 5AULA 2Y1MA 1A81A 3CXLA 1X6CA 2LQNA 1RJAA 1NZVA 3ZNIA 2SHPA 2MQIA 2CI9A 4P9VA 1TCEA 5CDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FYR A;  2BBU A;  4JEG A;  1BF5 A;  1RPY A;  5DC0 B;  4XZ0 A;  4H1O A;  1BHH B;  2EOB A;  2MC1 A;  2LNX A;  1MW4 A;  4L1B B;  2DLZ A;  3CD3 A;  1BFJ A;  2MRJ A;  1JYQ A;  4A4C A;  2EKX A;  1O4H A;  1O4I A;  2RSY A;  3T04 A;  1B47 A;  5BO4 A;  3IMD A;  2EU0 A;  1QG1 E;  2LQW A;  3S8N A;  1OPK A;  4EIH A;  3N8M A;  1K9A A;  1O4R A;  1O4L A;  1P13 A;  3BUM B;  3PSJ A;  4EY0 A;  3VRR A;  1O4P A;  2CI8 A;  4TZI A;  1FU5 A;  2K7A B;  1KSW A;  2SRC A;  1KA7 A;  1M27 A;  1UUS A;  2YSX A;  1O4G A;  1O4J A;  4OHI A;  2DX0 A;  3TKZ A;  5GJH A;  5GJI A;  5IBS A;  1A1E A;  3EAZ A;  4H34 A;  3BUO B;  3QWX X;  4JGH A;  3VS3 A;  1A08 A;  3VS0 A;  4X6S A;  3VS2 A;  5IBM A;  2AUG A;  4K44 A;  1CSZ A;  2EYY A;  2PLD A;  3BUX B;  2RMX A;  1LKL A;  3OVE A;  1O47 A;  1H9O A;  1LUK A;  1UUR A;  3N7Y A;  1O4F A;  2IUI A;  2PNA A;  3PLF B;  4FL2 A;  3VRZ A;  1WQU A;  1LUN A;  4NWG A;  2CIA A;  1O49 A;  5HKW A;  4FL3 A;  1FBV A;  5DC4 A;  4DGX A;  1O4M A;  4F5B A;  3VRP A;  3QWY A;  3GXX A;  3N84 A;  3US4 A;  1QAD A;  5DC9 A;  4NWF A;  1CWE A;  5KAZ A;  4FBN A;  1AYC A;  1FMK A;  1SPR A;  2ECD A;  1OO3 A;  2LCT A;  4K45 A;  4F59 A;  1A1A A;  1XA6 A;  1SHA A;  2IZV A;  1AOT F;  3OP0 A;  5AXI A;  2CRH A;  1IJR A;  4ROJ A;  1BFI A;  1NRV A;  3UYO A;  1GHU A;  1A09 A;  4OHD A;  3MXY A;  1BKM A;  1JYR A;  2GE9 A;  1PIC A;  2PTK A;  3VS4 A;  1SHB A;  3C7I A;  1F1W A;  3PS5 A;  2EO3 A;  1YVL A;  2GSB A;  2L3T A;  4GPL B;  2DVJ A;  1O4A A;  3IN7 A;  1D1Z A;  1AYD A;  1AOU F;  2L6K A;  3S8L A;  3IMJ A;  5EEQ A;  1IS0 A;  1BHF A;  3VS6 A;  4WWQ A;  1KC2 A;  2IUG A;  2FO0 A;  2PNB A;  2L4K A;  2C0O A;  1O4C A;  3OB1 B;  1AD5 A;  1BLJ A;  2EO6 A;  2CR4 A;  3VRQ A;  2QMS A;  1X27 A;  1ZFP E;  2DLY A;  1LCK A;  1Z3K A;  1I3Z A;  1CSY A;  1D4T A;  1A07 A;  3MAZ A;  1O45 A;  1GRI A;  2EYZ A;  3VS7 A;  1O4N A;  2IUH A;  1YVH A;  3VS5 A;  1BG1 A;  2DM0 A;  4U17 A;  3WA4 A;  3PJP A;  3GQI B;  3MXC A;  2H8H A;  2AOB A;  4DGP A;  1O4D A;  1OPL A;  2ABL A;  2VIF A;  5D0J A;  4LUD A;  1O4E A;  2B3O A;  1SPS A;  1X0N A;  2DCR A;  2MK2 A;  3TL0 A;  2PLE A;  3BUW B;  2K79 B;  1O4B A;  2AOA A;  4GL9 E;  1Y1U A;  1A1B A;  2C0I A;  4E93 A;  2H46 E;  4P9Z A;  1R1S A;  2MRK A;  2H5K A;  1SHD A;  1O43 A;  1O46 A;  3NHN A;  4M4Z A;  1O41 A;  2HUW A;  1RQQ C;  4A4B A;  5EEL A;  4OHL A;  1D4W A;  1G83 A;  4K11 A;  1R1P A;  1NZL A;  5I6V A;  3S8O A;  1M61 A;  5HKZ A;  1JYU A;  4F5A A;  2C0T A;  3VRO A;  1SKJ A;  3M7F A;  2LNW A;  3HCK A;  1LUM A;  2FCI A;  2JYQ A;  5EHP A;  1LKK A;  1CWD L;  2HDV A;  3VRY A;  3IN8 A;  3OV1 A;  3PQZ A;  2YU7 A;  1O48 A;  4U1P A;  2Y3A B;  1O4Q A;  1JU5 A;  3HHM B;  1BKL A;  2CS0 A;  1TZE E;  1HCT B;  1O4O A;  1LUI A;  2OQ1 A;  1KA6 A;  1O4K A;  3GXW A;  2HCK A;  4OHH A;  4GWF A;  4K2R A;  1HCS B;  1BLK A;  4E68 A;  3BKB A;  4XZ1 A;  3OB2 B;  2CBL A;  3CBL A;  1Y57 A;  3PFV A;  3VRN A;  1AYB A;  2Y1N A;  1BM2 A;  2ETZ A;  3CWG A;  2ROR A;  4LUE A;  1AYA A;  1FHS A;  5EG3 B;  3VS1 A;  1OO4 A;  5HKY A;  3BUN B;  2RVF A;  2HMH A;  3K2M A;  2EYV A;  2EL8 A;  3EAC A;  1BHH A;  3PSK A;  5DF6 A;  4QSY A;  2XP1 A;  1F2F A;  3S9K A;  2OZO A;  1CJ1 A;  1BMB A;  1MIL A;  1FU6 A;  4JE4 A;  5EHR A;  4D8K A;  1QCF A;  2HDX A;  1A1C A;  2KNO A;  2KK6 A;  1AB2 A;  2C9W A;  1FBZ A;  4OHE A;  3HIZ B;  3KFJ A;  5J3X A;  3UF4 A;  1R1Q A;  1O42 A;  3VGO A;  1JWO A;  1O44 A;  1LCJ A;  5AUL A;  2Y1M A;  1A81 A;  3CXL A;  1X6C A;  2LQN A;  1RJA A;  1NZV A;  3ZNI A;  2SHP A;  2MQI A;  2CI9 A;  4P9V A;  1TCE A;  5CDW A; 
#chains in the Genus database with same CATH topology
 1FYR A;  2BBU A;  4JEG A;  1BF5 A;  1RPY A;  5DC0 B;  4XZ0 A;  4H1O A;  1BHH B;  2EOB A;  2MC1 A;  2LNX A;  1MW4 A;  4L1B B;  2DLZ A;  3CD3 A;  1BFJ A;  2MRJ A;  1JYQ A;  4A4C A;  2EKX A;  1O4H A;  1O4I A;  2RSY A;  3T04 A;  1B47 A;  2LRA A;  5BO4 A;  3IMD A;  2EU0 A;  1QG1 E;  2LQW A;  3S8N A;  1OPK A;  4EIH A;  3N8M A;  1K9A A;  1O4R A;  3K2T A;  1O4L A;  1P13 A;  3BUM B;  3PSJ A;  4EY0 A;  3VRR A;  1O4P A;  2CI8 A;  4TZI A;  1FU5 A;  2K7A B;  1KSW A;  2SRC A;  1KA7 A;  1M27 A;  1UUS A;  2YSX A;  1O4G A;  1O4J A;  4OHI A;  2DX0 A;  3TKZ A;  5GJH A;  5GJI A;  5IBS A;  1A1E A;  3EAZ A;  4H34 A;  3BUO B;  3QWX X;  4JGH A;  3VS3 A;  1A08 A;  3VS0 A;  4X6S A;  3VS2 A;  5IBM A;  2AUG A;  4K44 A;  1CSZ A;  2EYY A;  2PLD A;  3BUX B;  2RMX A;  1LKL A;  3OVE A;  1O47 A;  1H9O A;  1LUK A;  1UUR A;  3N7Y A;  1O4F A;  2IUI A;  2PNA A;  3PLF B;  4FL2 A;  3VRZ A;  1WQU A;  3LYV A;  1LUN A;  4NWG A;  2CIA A;  1O49 A;  5HKW A;  4FL3 A;  1FBV A;  5DC4 A;  4DGX A;  1O4M A;  4F5B A;  3VRP A;  3QWY A;  3GXX A;  3N84 A;  3US4 A;  2KGY A;  1QAD A;  5DC9 A;  4NWF A;  1CWE A;  5KAZ A;  4FBN A;  1AYC A;  1FMK A;  1SPR A;  2ECD A;  1OO3 A;  2LCT A;  4K45 A;  4F59 A;  1A1A A;  1XA6 A;  1SHA A;  2IZV A;  1AOT F;  3OP0 A;  5AXI A;  2CRH A;  1IJR A;  4ROJ A;  1BFI A;  1NRV A;  3UYO A;  1GHU A;  1A09 A;  4OHD A;  3MXY A;  1BKM A;  1JYR A;  2GE9 A;  1PIC A;  2PTK A;  3VS4 A;  1SHB A;  3C7I A;  1F1W A;  3PS5 A;  2EO3 A;  1YVL A;  2GSB A;  2L3T A;  4GPL B;  2DVJ A;  1O4A A;  3IN7 A;  1D1Z A;  1AYD A;  1AOU F;  2L6K A;  3S8L A;  3IMJ A;  5EEQ A;  1IS0 A;  1BHF A;  3VS6 A;  4WWQ A;  1KC2 A;  2IUG A;  2FO0 A;  2PNB A;  2L4K A;  2C0O A;  1O4C A;  3OB1 B;  1AD5 A;  1BLJ A;  2EO6 A;  2CR4 A;  3VRQ A;  2QMS A;  1X27 A;  1ZFP E;  2DLY A;  1LCK A;  1Z3K A;  1I3Z A;  1CSY A;  1D4T A;  1A07 A;  3MAZ A;  1O45 A;  1GRI A;  2EYZ A;  3VS7 A;  1O4N A;  2IUH A;  1YVH A;  3VS5 A;  1BG1 A;  2DM0 A;  4U17 A;  3WA4 A;  3PJP A;  3GQI B;  3MXC A;  2H8H A;  2AOB A;  4DGP A;  1O4D A;  1OPL A;  2ABL A;  2VIF A;  5D0J A;  4LUD A;  1O4E A;  2B3O A;  1SPS A;  1X0N A;  2DCR A;  2MK2 A;  3TL0 A;  2PLE A;  3BUW B;  2K79 B;  1O4B A;  2AOA A;  4GL9 E;  1Y1U A;  1A1B A;  2C0I A;  4E93 A;  2H46 E;  4P9Z A;  1R1S A;  2MRK A;  2H5K A;  1SHD A;  1O43 A;  1O46 A;  3NHN A;  4M4Z A;  1O41 A;  2HUW A;  1RQQ C;  4A4B A;  5EEL A;  4OHL A;  1D4W A;  1G83 A;  4K11 A;  1R1P A;  1NZL A;  5I6V A;  3S8O A;  1M61 A;  5HKZ A;  1JYU A;  4F5A A;  2C0T A;  3VRO A;  1SKJ A;  3M7F A;  2LNW A;  3HCK A;  1LUM A;  2FCI A;  2JYQ A;  5EHP A;  1LKK A;  1CWD L;  2HDV A;  3VRY A;  3IN8 A;  3OV1 A;  3PQZ A;  2YU7 A;  1O48 A;  4U1P A;  2Y3A B;  1O4Q A;  1JU5 A;  3HHM B;  1BKL A;  2CS0 A;  1TZE E;  1HCT B;  1O4O A;  1LUI A;  2OQ1 A;  1KA6 A;  1O4K A;  3GXW A;  2HCK A;  4OHH A;  4GWF A;  4K2R A;  1HCS B;  1BLK A;  4E68 A;  3BKB A;  4XZ1 A;  3OB2 B;  2CBL A;  3CBL A;  1Y57 A;  3PFV A;  3VRN A;  1AYB A;  2Y1N A;  1BM2 A;  2ETZ A;  3CWG A;  2ROR A;  4LUE A;  1AYA A;  1FHS A;  5EG3 B;  3VS1 A;  1OO4 A;  5HKY A;  3BUN B;  2RVF A;  2HMH A;  3K2M A;  2EYV A;  2EL8 A;  3EAC A;  1BHH A;  3PSK A;  5DF6 A;  4QSY A;  2XP1 A;  1F2F A;  3S9K A;  2OZO A;  1CJ1 A;  1BMB A;  1MIL A;  1FU6 A;  4JE4 A;  5EHR A;  4D8K A;  1QCF A;  2HDX A;  1A1C A;  2KNO A;  2KK6 A;  1AB2 A;  2C9W A;  1FBZ A;  4OHE A;  3HIZ B;  3KFJ A;  5J3X A;  3UF4 A;  1R1Q A;  1O42 A;  3VGO A;  1JWO A;  1O44 A;  1LCJ A;  5AUL A;  2Y1M A;  1A81 A;  3CXL A;  1X6C A;  2LQN A;  1RJA A;  1NZV A;  3ZNI A;  2SHP A;  2MQI A;  2CI9 A;  4P9V A;  1TCE A;  5CDW A; 
#chains in the Genus database with same CATH homology
 1FYR A;  2BBU A;  4JEG A;  1BF5 A;  1RPY A;  5DC0 B;  4XZ0 A;  4H1O A;  1BHH B;  2EOB A;  2MC1 A;  2LNX A;  1MW4 A;  4L1B B;  2DLZ A;  3CD3 A;  1BFJ A;  2MRJ A;  1JYQ A;  4A4C A;  2EKX A;  1O4H A;  1O4I A;  2RSY A;  3T04 A;  1B47 A;  5BO4 A;  3IMD A;  2EU0 A;  1QG1 E;  2LQW A;  3S8N A;  1OPK A;  4EIH A;  3N8M A;  1K9A A;  1O4R A;  1O4L A;  1P13 A;  3BUM B;  3PSJ A;  4EY0 A;  3VRR A;  1O4P A;  2CI8 A;  4TZI A;  1FU5 A;  2K7A B;  1KSW A;  2SRC A;  1KA7 A;  1M27 A;  1UUS A;  2YSX A;  1O4G A;  1O4J A;  4OHI A;  2DX0 A;  3TKZ A;  5GJH A;  5GJI A;  5IBS A;  1A1E A;  3EAZ A;  4H34 A;  3BUO B;  3QWX X;  4JGH A;  3VS3 A;  1A08 A;  3VS0 A;  4X6S A;  3VS2 A;  5IBM A;  2AUG A;  4K44 A;  1CSZ A;  2EYY A;  2PLD A;  3BUX B;  2RMX A;  1LKL A;  3OVE A;  1O47 A;  1H9O A;  1LUK A;  1UUR A;  3N7Y A;  1O4F A;  2IUI A;  2PNA A;  3PLF B;  4FL2 A;  3VRZ A;  1WQU A;  1LUN A;  4NWG A;  2CIA A;  1O49 A;  5HKW A;  4FL3 A;  1FBV A;  5DC4 A;  4DGX A;  1O4M A;  4F5B A;  3VRP A;  3QWY A;  3GXX A;  3N84 A;  3US4 A;  1QAD A;  5DC9 A;  4NWF A;  1CWE A;  5KAZ A;  4FBN A;  1AYC A;  1FMK A;  1SPR A;  2ECD A;  1OO3 A;  2LCT A;  4K45 A;  4F59 A;  1A1A A;  1XA6 A;  1SHA A;  2IZV A;  1AOT F;  3OP0 A;  5AXI A;  2CRH A;  1IJR A;  4ROJ A;  1BFI A;  1NRV A;  3UYO A;  1GHU A;  1A09 A;  4OHD A;  3MXY A;  1BKM A;  1JYR A;  2GE9 A;  1PIC A;  2PTK A;  3VS4 A;  1SHB A;  3C7I A;  1F1W A;  3PS5 A;  2EO3 A;  1YVL A;  2GSB A;  2L3T A;  4GPL B;  2DVJ A;  1O4A A;  3IN7 A;  1D1Z A;  1AYD A;  1AOU F;  2L6K A;  3S8L A;  3IMJ A;  5EEQ A;  1IS0 A;  1BHF A;  3VS6 A;  4WWQ A;  1KC2 A;  2IUG A;  2FO0 A;  2PNB A;  2L4K A;  2C0O A;  1O4C A;  3OB1 B;  1AD5 A;  1BLJ A;  2EO6 A;  2CR4 A;  3VRQ A;  2QMS A;  1X27 A;  1ZFP E;  2DLY A;  1LCK A;  1Z3K A;  1I3Z A;  1CSY A;  1D4T A;  1A07 A;  3MAZ A;  1O45 A;  1GRI A;  2EYZ A;  3VS7 A;  1O4N A;  2IUH A;  1YVH A;  3VS5 A;  1BG1 A;  2DM0 A;  4U17 A;  3WA4 A;  3PJP A;  3GQI B;  3MXC A;  2H8H A;  2AOB A;  4DGP A;  1O4D A;  1OPL A;  2ABL A;  2VIF A;  5D0J A;  4LUD A;  1O4E A;  2B3O A;  1SPS A;  1X0N A;  2DCR A;  2MK2 A;  3TL0 A;  2PLE A;  3BUW B;  2K79 B;  1O4B A;  2AOA A;  4GL9 E;  1Y1U A;  1A1B A;  2C0I A;  4E93 A;  2H46 E;  4P9Z A;  1R1S A;  2MRK A;  2H5K A;  1SHD A;  1O43 A;  1O46 A;  3NHN A;  4M4Z A;  1O41 A;  2HUW A;  1RQQ C;  4A4B A;  5EEL A;  4OHL A;  1D4W A;  1G83 A;  4K11 A;  1R1P A;  1NZL A;  5I6V A;  3S8O A;  1M61 A;  5HKZ A;  1JYU A;  4F5A A;  2C0T A;  3VRO A;  1SKJ A;  3M7F A;  2LNW A;  3HCK A;  1LUM A;  2FCI A;  2JYQ A;  5EHP A;  1LKK A;  1CWD L;  2HDV A;  3VRY A;  3IN8 A;  3OV1 A;  3PQZ A;  2YU7 A;  1O48 A;  4U1P A;  2Y3A B;  1O4Q A;  1JU5 A;  3HHM B;  1BKL A;  2CS0 A;  1TZE E;  1HCT B;  1O4O A;  1LUI A;  2OQ1 A;  1KA6 A;  1O4K A;  3GXW A;  2HCK A;  4OHH A;  4GWF A;  4K2R A;  1HCS B;  1BLK A;  4E68 A;  3BKB A;  4XZ1 A;  3OB2 B;  2CBL A;  3CBL A;  1Y57 A;  3PFV A;  3VRN A;  1AYB A;  2Y1N A;  1BM2 A;  2ETZ A;  3CWG A;  2ROR A;  4LUE A;  1AYA A;  1FHS A;  5EG3 B;  3VS1 A;  1OO4 A;  5HKY A;  3BUN B;  2RVF A;  2HMH A;  3K2M A;  2EYV A;  2EL8 A;  3EAC A;  1BHH A;  3PSK A;  5DF6 A;  4QSY A;  2XP1 A;  1F2F A;  3S9K A;  2OZO A;  1CJ1 A;  1BMB A;  1MIL A;  1FU6 A;  4JE4 A;  5EHR A;  4D8K A;  1QCF A;  2HDX A;  1A1C A;  2KNO A;  2KK6 A;  1AB2 A;  2C9W A;  1FBZ A;  4OHE A;  3HIZ B;  3KFJ A;  5J3X A;  3UF4 A;  1R1Q A;  1O42 A;  3VGO A;  1JWO A;  1O44 A;  1LCJ A;  5AUL A;  2Y1M A;  1A81 A;  3CXL A;  1X6C A;  2LQN A;  1RJA A;  1NZV A;  3ZNI A;  2SHP A;  2MQI A;  2CI9 A;  4P9V A;  1TCE A;  5CDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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