4K45A

Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
QAESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
total genus 26
structure length 102
sequence length 102
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2013-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4k45A00
1KA7A 1F1WA 1NZVA 3HHMB 1CWEA 4U17A 2KK6A 5D0JA 3WA4A 3C7IA 4K2RA 3PSKA 3GXWA 1A1CA 4OHEA 1LUKA 2SHPA 3BUXB 1AYBA 1CSZA 2EO6A 2GE9A 2MRJA 2CR4A 5EG3B 1O4KA 2EKXA 1O41A 1FU6A 1QG1E 1OPLA 4F59A 4JE4A 3VROA 4LUEA 2HUWA 2HDXA 2EU0A 1OO4A 1LUIA 3BUOB 2QMSA 5DC4A 3MXCA 1R1PA 1SHAA 5I6VA 3VS5A 5IBSA 1SPRA 5DC9A 4FL2A 1BG1A 3UYOA 3VS6A 1PICA 3VRNA 2MK2A 2DCRA 4P9VA 3GXXA 1B47A 3QWXX 1KSWA 4F5AA 1D4WA 1NZLA 2SRCA 2L3TA 4OHLA 3HCKA 3VS3A 1BLKA 2L4KA 4FBNA 1HCTB 3TL0A 3OV1A 1JYQA 1MILA 1A09A 1HCSB 1TCEA 1O4RA 1LKLA 1K9AA 1MW4A 4K44A 2EL8A 2AUGA 1A08A 5GJHA 2HCKA 2RMXA 3VGOA 3VRQA 4K45A 1UURA 3BUWB 2Y1MA 1Y1UA 1WQUA 5KAZA 3OB1B 5GJIA 2MQIA 1A07A 1O4OA 1LKKA 3PJPA 4K11A 1AB2A 1LCKA 5HKYA 2PNBA 1AD5A 1BHFA 3BUNB 2CIAA 1BFJA 2LNWA 1AOTF 1KC2A 2VIFA 5IBMA 2XP1A 2EYVA 3OVEA 4LUDA 2AOBA 2IUHA 5DC0B 4U1PA 1JYRA 2PNAA 1CJ1A 4H1OA 4JEGA 5HKZA 2H46E 1FBZA 1SHBA 4F5BA 1BFIA 1O4FA 4WWQA 3VS0A 2EO3A 2CI8A 1KA6A 4E68A 4A4BA 3BKBA 1O4HA 1OPKA 1LUNA 1IJRA 1CWDL 3EACA 1A1AA 2FO0A 1I3ZA 2PLDA 3K2MA 1O4PA 2H5KA 3NHNA 2BBUA 4D8KA 1IS0A 1O44A 3EAZA 2B3OA 4DGXA 5HKWA 3US4A 4ROJA 1H9OA 1A81A 5CDWA 1LUMA 3PSJA 3N7YA 1RQQC 4TZIA 1O47A 2L6KA 2ABLA 2OZOA 2CBLA 5J3XA 2LQNA 3OP0A 1NRVA 1SHDA 2LCTA 1BKLA 2RVFA 2EYZA 4E93A 4QSYA 1O4MA 2FCIA 2K79B 3CD3A 5EHPA 4NWGA 2HDVA 2HMHA 1YVHA 2ETZA 2EOBA 2IZVA 2YSXA 4A4CA 1ZFPE 3PQZA 4JGHA 3CBLA 3IN7A 3VRYA 3S9KA 1O4DA 2YU7A 4NWFA 1AYCA 1SKJA 2IUIA 3S8NA 1GRIA 5DF6A 4L1BB 4OHDA 2CS0A 2RORA 5BO4A 1XA6A 4DGPA 4OHHA 2C0TA 1BM2A 1D1ZA 4GL9E 2RSYA 3S8LA 1R1SA 2EYYA 2C9WA 4FL3A 1FYRA 3S8OA 1FMKA 1FU5A 2Y3AB 2C0IA 1O4QA 4X6SA 3MXYA 2KNOA 1G83A 1BF5A 3M7FA 1Y57A 2CI9A 3PLFB 1RJAA 1BHHA 1RPYA 1QADA 1GHUA 3TKZA 1M27A 2OQ1A 1O4GA 3BUMB 2K7AB 3VRPA 4EY0A 5EELA 2PTKA 3VS4A 1BLJA 2IUGA 3N84A 4GPLB 1JU5A 3VS7A 2C0OA 2GSBA 1O46A 4XZ1A 4H34A 1YVLA 2AOAA 4M4ZA 1O48A 2MRKA 5EEQA 3OB2B 1O4BA 1O4IA 1O45A 4XZ0A 1OO3A 3VRRA 1SPSA 1TZEE 1X27A 1O49A 3CXLA 1FHSA 1BHHB 1R1QA 3N8MA 1JWOA 2DLZA 3GQIB 1CSYA 3QWYA 2DLYA 1O4EA 4GWFA 3ZNIA 3PS5A 3KFJA 1F2FA 1LCJA 1P13A 1O42A 1A1EA 1QCFA 1AYDA 1UUSA 3IMJA 1AYAA 4EIHA 2JYQA 2LQWA 2DVJA 3VRZA 2Y1NA 1O4LA 1A1BA 1FBVA 5EHRA 5AULA 1Z3KA 3PFVA 1X0NA 1BMBA 2PLEA 1O4AA 4OHIA 3VS2A 2ECDA 1D4TA 1O4NA 2CRHA 1X6CA 3UF4A 4P9ZA 2H8HA 2MC1A 3IN8A 1AOUF 3MAZA 5AXIA 2DM0A 1O43A 3VS1A 1JYUA 1O4JA 1M61A 3HIZB 3CWGA 1BKMA 2DX0A 3IMDA 2LNXA 3T04A 1O4CA
chains in the Genus database with same CATH superfamily
1KA7A 1F1WA 1NZVA 3HHMB 1CWEA 4U17A 2KK6A 5D0JA 3WA4A 3C7IA 4K2RA 3PSKA 3GXWA 1A1CA 4OHEA 1LUKA 2SHPA 3BUXB 1AYBA 1CSZA 2EO6A 2GE9A 2MRJA 2CR4A 5EG3B 1O4KA 2EKXA 1O41A 1FU6A 1QG1E 1OPLA 4F59A 4JE4A 3VROA 4LUEA 2HUWA 2HDXA 2EU0A 1OO4A 1LUIA 3BUOB 2QMSA 5DC4A 3MXCA 1R1PA 1SHAA 5I6VA 3VS5A 5IBSA 1SPRA 5DC9A 4FL2A 1BG1A 3UYOA 3VS6A 1PICA 3VRNA 2MK2A 2DCRA 4P9VA 3GXXA 1B47A 3QWXX 1KSWA 4F5AA 1D4WA 1NZLA 2SRCA 2L3TA 4OHLA 3HCKA 3VS3A 1BLKA 2L4KA 4FBNA 1HCTB 3TL0A 3OV1A 1JYQA 1MILA 1A09A 1HCSB 1TCEA 1O4RA 1LKLA 1K9AA 1MW4A 4K44A 2EL8A 2AUGA 1A08A 5GJHA 2HCKA 2RMXA 3VGOA 3VRQA 4K45A 1UURA 3BUWB 2Y1MA 1Y1UA 1WQUA 5KAZA 3OB1B 3K2TA 5GJIA 2MQIA 1A07A 1O4OA 1LKKA 3PJPA 4K11A 1AB2A 1LCKA 5HKYA 2PNBA 1AD5A 1BHFA 3BUNB 2CIAA 1BFJA 2LNWA 1AOTF 1KC2A 2VIFA 5IBMA 2XP1A 2EYVA 3OVEA 4LUDA 2AOBA 2IUHA 5DC0B 4U1PA 1JYRA 2PNAA 1CJ1A 4H1OA 4JEGA 5HKZA 2H46E 1FBZA 1SHBA 4F5BA 1BFIA 1O4FA 4WWQA 3VS0A 2EO3A 2CI8A 1KA6A 4E68A 4A4BA 3BKBA 1O4HA 1OPKA 1LUNA 1IJRA 1CWDL 3EACA 1A1AA 2FO0A 1I3ZA 2PLDA 3K2MA 1O4PA 2H5KA 3NHNA 2BBUA 4D8KA 1IS0A 1O44A 3EAZA 2B3OA 4DGXA 5HKWA 3US4A 4ROJA 1H9OA 1A81A 5CDWA 1LUMA 3PSJA 3N7YA 1RQQC 4TZIA 1O47A 2L6KA 2ABLA 2OZOA 2CBLA 5J3XA 2LQNA 3OP0A 1NRVA 1SHDA 2LCTA 1BKLA 2KGYA 2RVFA 2EYZA 4E93A 4QSYA 1O4MA 2FCIA 2K79B 3CD3A 5EHPA 4NWGA 2HDVA 2HMHA 1YVHA 2ETZA 2EOBA 2IZVA 2YSXA 4A4CA 1ZFPE 3PQZA 4JGHA 3CBLA 3IN7A 3VRYA 3S9KA 1O4DA 2YU7A 4NWFA 1AYCA 1SKJA 2IUIA 3S8NA 1GRIA 5DF6A 4L1BB 4OHDA 2CS0A 2RORA 5BO4A 1XA6A 4DGPA 4OHHA 2C0TA 1BM2A 1D1ZA 4GL9E 2RSYA 3S8LA 1R1SA 2EYYA 2C9WA 4FL3A 1FYRA 3S8OA 1FMKA 1FU5A 2Y3AB 2C0IA 1O4QA 4X6SA 3MXYA 2KNOA 1G83A 1BF5A 3M7FA 1Y57A 2CI9A 3PLFB 1RJAA 1BHHA 1RPYA 1QADA 1GHUA 3TKZA 1M27A 2OQ1A 1O4GA 3BUMB 2K7AB 3VRPA 4EY0A 5EELA 2PTKA 3VS4A 1BLJA 2IUGA 3N84A 4GPLB 1JU5A 3VS7A 2C0OA 2GSBA 1O46A 4XZ1A 4H34A 1YVLA 2AOAA 2LRAA 4M4ZA 1O48A 2MRKA 5EEQA 3OB2B 1O4BA 1O4IA 1O45A 4XZ0A 1OO3A 3VRRA 1SPSA 1TZEE 1X27A 1O49A 3CXLA 1FHSA 1BHHB 1R1QA 3N8MA 1JWOA 2DLZA 3GQIB 1CSYA 3QWYA 2DLYA 1O4EA 4GWFA 3ZNIA 3PS5A 3KFJA 1F2FA 1LCJA 1P13A 1O42A 1A1EA 1QCFA 1AYDA 1UUSA 3IMJA 1AYAA 4EIHA 2JYQA 2LQWA 2DVJA 3VRZA 2Y1NA 1O4LA 1A1BA 1FBVA 5EHRA 5AULA 1Z3KA 3PFVA 1X0NA 1BMBA 2PLEA 1O4AA 4OHIA 3VS2A 2ECDA 1D4TA 1O4NA 2CRHA 1X6CA 3UF4A 4P9ZA 2H8HA 2MC1A 3IN8A 1AOUF 3MAZA 5AXIA 2DM0A 1O43A 3LYVA 3VS1A 1JYUA 1O4JA 1M61A 3HIZB 3CWGA 1BKMA 2DX0A 3IMDA 2LNXA 3T04A 1O4CA
chains in the Genus database with same CATH topology
1KA7A 1F1WA 1NZVA 3HHMB 1CWEA 4U17A 2KK6A 5D0JA 3WA4A 3C7IA 4K2RA 3PSKA 3GXWA 1A1CA 4OHEA 1LUKA 2SHPA 3BUXB 1AYBA 1CSZA 2EO6A 2GE9A 2MRJA 2CR4A 5EG3B 1O4KA 2EKXA 1O41A 1FU6A 1QG1E 1OPLA 4F59A 4JE4A 3VROA 4LUEA 2HUWA 2HDXA 2EU0A 1OO4A 1LUIA 3BUOB 2QMSA 5DC4A 3MXCA 1R1PA 1SHAA 5I6VA 3VS5A 5IBSA 1SPRA 5DC9A 4FL2A 1BG1A 3UYOA 3VS6A 1PICA 3VRNA 2MK2A 2DCRA 4P9VA 3GXXA 1B47A 3QWXX 1KSWA 4F5AA 1D4WA 1NZLA 2SRCA 2L3TA 4OHLA 3HCKA 3VS3A 1BLKA 2L4KA 4FBNA 1HCTB 3TL0A 3OV1A 1JYQA 1MILA 1A09A 1HCSB 1TCEA 1O4RA 1LKLA 1K9AA 1MW4A 4K44A 2EL8A 2AUGA 1A08A 5GJHA 2HCKA 2RMXA 3VGOA 3VRQA 4K45A 1UURA 3BUWB 2Y1MA 1Y1UA 1WQUA 5KAZA 3OB1B 5GJIA 2MQIA 1A07A 1O4OA 1LKKA 3PJPA 4K11A 1AB2A 1LCKA 5HKYA 2PNBA 1AD5A 1BHFA 3BUNB 2CIAA 1BFJA 2LNWA 1AOTF 1KC2A 2VIFA 5IBMA 2XP1A 2EYVA 3OVEA 4LUDA 2AOBA 2IUHA 5DC0B 4U1PA 1JYRA 2PNAA 1CJ1A 4H1OA 4JEGA 5HKZA 2H46E 1FBZA 1SHBA 4F5BA 1BFIA 1O4FA 4WWQA 3VS0A 2EO3A 2CI8A 1KA6A 4E68A 4A4BA 3BKBA 1O4HA 1OPKA 1LUNA 1IJRA 1CWDL 3EACA 1A1AA 2FO0A 1I3ZA 2PLDA 3K2MA 1O4PA 2H5KA 3NHNA 2BBUA 4D8KA 1IS0A 1O44A 3EAZA 2B3OA 4DGXA 5HKWA 3US4A 4ROJA 1H9OA 1A81A 5CDWA 1LUMA 3PSJA 3N7YA 1RQQC 4TZIA 1O47A 2L6KA 2ABLA 2OZOA 2CBLA 5J3XA 2LQNA 3OP0A 1NRVA 1SHDA 2LCTA 1BKLA 2RVFA 2EYZA 4E93A 4QSYA 1O4MA 2FCIA 2K79B 3CD3A 5EHPA 4NWGA 2HDVA 2HMHA 1YVHA 2ETZA 2EOBA 2IZVA 2YSXA 4A4CA 1ZFPE 3PQZA 4JGHA 3CBLA 3IN7A 3VRYA 3S9KA 1O4DA 2YU7A 4NWFA 1AYCA 1SKJA 2IUIA 3S8NA 1GRIA 5DF6A 4L1BB 4OHDA 2CS0A 2RORA 5BO4A 1XA6A 4DGPA 4OHHA 2C0TA 1BM2A 1D1ZA 4GL9E 2RSYA 3S8LA 1R1SA 2EYYA 2C9WA 4FL3A 1FYRA 3S8OA 1FMKA 1FU5A 2Y3AB 2C0IA 1O4QA 4X6SA 3MXYA 2KNOA 1G83A 1BF5A 3M7FA 1Y57A 2CI9A 3PLFB 1RJAA 1BHHA 1RPYA 1QADA 1GHUA 3TKZA 1M27A 2OQ1A 1O4GA 3BUMB 2K7AB 3VRPA 4EY0A 5EELA 2PTKA 3VS4A 1BLJA 2IUGA 3N84A 4GPLB 1JU5A 3VS7A 2C0OA 2GSBA 1O46A 4XZ1A 4H34A 1YVLA 2AOAA 4M4ZA 1O48A 2MRKA 5EEQA 3OB2B 1O4BA 1O4IA 1O45A 4XZ0A 1OO3A 3VRRA 1SPSA 1TZEE 1X27A 1O49A 3CXLA 1FHSA 1BHHB 1R1QA 3N8MA 1JWOA 2DLZA 3GQIB 1CSYA 3QWYA 2DLYA 1O4EA 4GWFA 3ZNIA 3PS5A 3KFJA 1F2FA 1LCJA 1P13A 1O42A 1A1EA 1QCFA 1AYDA 1UUSA 3IMJA 1AYAA 4EIHA 2JYQA 2LQWA 2DVJA 3VRZA 2Y1NA 1O4LA 1A1BA 1FBVA 5EHRA 5AULA 1Z3KA 3PFVA 1X0NA 1BMBA 2PLEA 1O4AA 4OHIA 3VS2A 2ECDA 1D4TA 1O4NA 2CRHA 1X6CA 3UF4A 4P9ZA 2H8HA 2MC1A 3IN8A 1AOUF 3MAZA 5AXIA 2DM0A 1O43A 3VS1A 1JYUA 1O4JA 1M61A 3HIZB 3CWGA 1BKMA 2DX0A 3IMDA 2LNXA 3T04A 1O4CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KA7 A;  1F1W A;  1NZV A;  3HHM B;  1CWE A;  4U17 A;  2KK6 A;  5D0J A;  3WA4 A;  3C7I A;  4K2R A;  3PSK A;  3GXW A;  1A1C A;  4OHE A;  1LUK A;  2SHP A;  3BUX B;  1AYB A;  1CSZ A;  2EO6 A;  2GE9 A;  2MRJ A;  2CR4 A;  5EG3 B;  1O4K A;  2EKX A;  1O41 A;  1FU6 A;  1QG1 E;  1OPL A;  4F59 A;  4JE4 A;  3VRO A;  4LUE A;  2HUW A;  2HDX A;  2EU0 A;  1OO4 A;  1LUI A;  3BUO B;  2QMS A;  5DC4 A;  3MXC A;  1R1P A;  1SHA A;  5I6V A;  3VS5 A;  5IBS A;  1SPR A;  5DC9 A;  4FL2 A;  1BG1 A;  3UYO A;  3VS6 A;  1PIC A;  3VRN A;  2MK2 A;  2DCR A;  4P9V A;  3GXX A;  1B47 A;  3QWX X;  1KSW A;  4F5A A;  1D4W A;  1NZL A;  2SRC A;  2L3T A;  4OHL A;  3HCK A;  3VS3 A;  1BLK A;  2L4K A;  4FBN A;  1HCT B;  3TL0 A;  3OV1 A;  1JYQ A;  1MIL A;  1A09 A;  1HCS B;  1TCE A;  1O4R A;  1LKL A;  1K9A A;  1MW4 A;  4K44 A;  2EL8 A;  2AUG A;  1A08 A;  5GJH A;  2HCK A;  2RMX A;  3VGO A;  3VRQ A;  4K45 A;  1UUR A;  3BUW B;  2Y1M A;  1Y1U A;  1WQU A;  5KAZ A;  3OB1 B;  5GJI A;  2MQI A;  1A07 A;  1O4O A;  1LKK A;  3PJP A;  4K11 A;  1AB2 A;  1LCK A;  5HKY A;  2PNB A;  1AD5 A;  1BHF A;  3BUN B;  2CIA A;  1BFJ A;  2LNW A;  1AOT F;  1KC2 A;  2VIF A;  5IBM A;  2XP1 A;  2EYV A;  3OVE A;  4LUD A;  2AOB A;  2IUH A;  5DC0 B;  4U1P A;  1JYR A;  2PNA A;  1CJ1 A;  4H1O A;  4JEG A;  5HKZ A;  2H46 E;  1FBZ A;  1SHB A;  4F5B A;  1BFI A;  1O4F A;  4WWQ A;  3VS0 A;  2EO3 A;  2CI8 A;  1KA6 A;  4E68 A;  4A4B A;  3BKB A;  1O4H A;  1OPK A;  1LUN A;  1IJR A;  1CWD L;  3EAC A;  1A1A A;  2FO0 A;  1I3Z A;  2PLD A;  3K2M A;  1O4P A;  2H5K A;  3NHN A;  2BBU A;  4D8K A;  1IS0 A;  1O44 A;  3EAZ A;  2B3O A;  4DGX A;  5HKW A;  3US4 A;  4ROJ A;  1H9O A;  1A81 A;  5CDW A;  1LUM A;  3PSJ A;  3N7Y A;  1RQQ C;  4TZI A;  1O47 A;  2L6K A;  2ABL A;  2OZO A;  2CBL A;  5J3X A;  2LQN A;  3OP0 A;  1NRV A;  1SHD A;  2LCT A;  1BKL A;  2RVF A;  2EYZ A;  4E93 A;  4QSY A;  1O4M A;  2FCI A;  2K79 B;  3CD3 A;  5EHP A;  4NWG A;  2HDV A;  2HMH A;  1YVH A;  2ETZ A;  2EOB A;  2IZV A;  2YSX A;  4A4C A;  1ZFP E;  3PQZ A;  4JGH A;  3CBL A;  3IN7 A;  3VRY A;  3S9K A;  1O4D A;  2YU7 A;  4NWF A;  1AYC A;  1SKJ A;  2IUI A;  3S8N A;  1GRI A;  5DF6 A;  4L1B B;  4OHD A;  2CS0 A;  2ROR A;  5BO4 A;  1XA6 A;  4DGP A;  4OHH A;  2C0T A;  1BM2 A;  1D1Z A;  4GL9 E;  2RSY A;  3S8L A;  1R1S A;  2EYY A;  2C9W A;  4FL3 A;  1FYR A;  3S8O A;  1FMK A;  1FU5 A;  2Y3A B;  2C0I A;  1O4Q A;  4X6S A;  3MXY A;  2KNO A;  1G83 A;  1BF5 A;  3M7F A;  1Y57 A;  2CI9 A;  3PLF B;  1RJA A;  1BHH A;  1RPY A;  1QAD A;  1GHU A;  3TKZ A;  1M27 A;  2OQ1 A;  1O4G A;  3BUM B;  2K7A B;  3VRP A;  4EY0 A;  5EEL A;  2PTK A;  3VS4 A;  1BLJ A;  2IUG A;  3N84 A;  4GPL B;  1JU5 A;  3VS7 A;  2C0O A;  2GSB A;  1O46 A;  4XZ1 A;  4H34 A;  1YVL A;  2AOA A;  4M4Z A;  1O48 A;  2MRK A;  5EEQ A;  3OB2 B;  1O4B A;  1O4I A;  1O45 A;  4XZ0 A;  1OO3 A;  3VRR A;  1SPS A;  1TZE E;  1X27 A;  1O49 A;  3CXL A;  1FHS A;  1BHH B;  1R1Q A;  3N8M A;  1JWO A;  2DLZ A;  3GQI B;  1CSY A;  3QWY A;  2DLY A;  1O4E A;  4GWF A;  3ZNI A;  3PS5 A;  3KFJ A;  1F2F A;  1LCJ A;  1P13 A;  1O42 A;  1A1E A;  1QCF A;  1AYD A;  1UUS A;  3IMJ A;  1AYA A;  4EIH A;  2JYQ A;  2LQW A;  2DVJ A;  3VRZ A;  2Y1N A;  1O4L A;  1A1B A;  1FBV A;  5EHR A;  5AUL A;  1Z3K A;  3PFV A;  1X0N A;  1BMB A;  2PLE A;  1O4A A;  4OHI A;  3VS2 A;  2ECD A;  1D4T A;  1O4N A;  2CRH A;  1X6C A;  3UF4 A;  4P9Z A;  2H8H A;  2MC1 A;  3IN8 A;  1AOU F;  3MAZ A;  5AXI A;  2DM0 A;  1O43 A;  3VS1 A;  1JYU A;  1O4J A;  1M61 A;  3HIZ B;  3CWG A;  1BKM A;  2DX0 A;  3IMD A;  2LNX A;  3T04 A;  1O4C A; 
#chains in the Genus database with same CATH topology
 1KA7 A;  1F1W A;  1NZV A;  3HHM B;  1CWE A;  4U17 A;  2KK6 A;  5D0J A;  3WA4 A;  3C7I A;  4K2R A;  3PSK A;  3GXW A;  1A1C A;  4OHE A;  1LUK A;  2SHP A;  3BUX B;  1AYB A;  1CSZ A;  2EO6 A;  2GE9 A;  2MRJ A;  2CR4 A;  5EG3 B;  1O4K A;  2EKX A;  1O41 A;  1FU6 A;  1QG1 E;  1OPL A;  4F59 A;  4JE4 A;  3VRO A;  4LUE A;  2HUW A;  2HDX A;  2EU0 A;  1OO4 A;  1LUI A;  3BUO B;  2QMS A;  5DC4 A;  3MXC A;  1R1P A;  1SHA A;  5I6V A;  3VS5 A;  5IBS A;  1SPR A;  5DC9 A;  4FL2 A;  1BG1 A;  3UYO A;  3VS6 A;  1PIC A;  3VRN A;  2MK2 A;  2DCR A;  4P9V A;  3GXX A;  1B47 A;  3QWX X;  1KSW A;  4F5A A;  1D4W A;  1NZL A;  2SRC A;  2L3T A;  4OHL A;  3HCK A;  3VS3 A;  1BLK A;  2L4K A;  4FBN A;  1HCT B;  3TL0 A;  3OV1 A;  1JYQ A;  1MIL A;  1A09 A;  1HCS B;  1TCE A;  1O4R A;  1LKL A;  1K9A A;  1MW4 A;  4K44 A;  2EL8 A;  2AUG A;  1A08 A;  5GJH A;  2HCK A;  2RMX A;  3VGO A;  3VRQ A;  4K45 A;  1UUR A;  3BUW B;  2Y1M A;  1Y1U A;  1WQU A;  5KAZ A;  3OB1 B;  3K2T A;  5GJI A;  2MQI A;  1A07 A;  1O4O A;  1LKK A;  3PJP A;  4K11 A;  1AB2 A;  1LCK A;  5HKY A;  2PNB A;  1AD5 A;  1BHF A;  3BUN B;  2CIA A;  1BFJ A;  2LNW A;  1AOT F;  1KC2 A;  2VIF A;  5IBM A;  2XP1 A;  2EYV A;  3OVE A;  4LUD A;  2AOB A;  2IUH A;  5DC0 B;  4U1P A;  1JYR A;  2PNA A;  1CJ1 A;  4H1O A;  4JEG A;  5HKZ A;  2H46 E;  1FBZ A;  1SHB A;  4F5B A;  1BFI A;  1O4F A;  4WWQ A;  3VS0 A;  2EO3 A;  2CI8 A;  1KA6 A;  4E68 A;  4A4B A;  3BKB A;  1O4H A;  1OPK A;  1LUN A;  1IJR A;  1CWD L;  3EAC A;  1A1A A;  2FO0 A;  1I3Z A;  2PLD A;  3K2M A;  1O4P A;  2H5K A;  3NHN A;  2BBU A;  4D8K A;  1IS0 A;  1O44 A;  3EAZ A;  2B3O A;  4DGX A;  5HKW A;  3US4 A;  4ROJ A;  1H9O A;  1A81 A;  5CDW A;  1LUM A;  3PSJ A;  3N7Y A;  1RQQ C;  4TZI A;  1O47 A;  2L6K A;  2ABL A;  2OZO A;  2CBL A;  5J3X A;  2LQN A;  3OP0 A;  1NRV A;  1SHD A;  2LCT A;  1BKL A;  2KGY A;  2RVF A;  2EYZ A;  4E93 A;  4QSY A;  1O4M A;  2FCI A;  2K79 B;  3CD3 A;  5EHP A;  4NWG A;  2HDV A;  2HMH A;  1YVH A;  2ETZ A;  2EOB A;  2IZV A;  2YSX A;  4A4C A;  1ZFP E;  3PQZ A;  4JGH A;  3CBL A;  3IN7 A;  3VRY A;  3S9K A;  1O4D A;  2YU7 A;  4NWF A;  1AYC A;  1SKJ A;  2IUI A;  3S8N A;  1GRI A;  5DF6 A;  4L1B B;  4OHD A;  2CS0 A;  2ROR A;  5BO4 A;  1XA6 A;  4DGP A;  4OHH A;  2C0T A;  1BM2 A;  1D1Z A;  4GL9 E;  2RSY A;  3S8L A;  1R1S A;  2EYY A;  2C9W A;  4FL3 A;  1FYR A;  3S8O A;  1FMK A;  1FU5 A;  2Y3A B;  2C0I A;  1O4Q A;  4X6S A;  3MXY A;  2KNO A;  1G83 A;  1BF5 A;  3M7F A;  1Y57 A;  2CI9 A;  3PLF B;  1RJA A;  1BHH A;  1RPY A;  1QAD A;  1GHU A;  3TKZ A;  1M27 A;  2OQ1 A;  1O4G A;  3BUM B;  2K7A B;  3VRP A;  4EY0 A;  5EEL A;  2PTK A;  3VS4 A;  1BLJ A;  2IUG A;  3N84 A;  4GPL B;  1JU5 A;  3VS7 A;  2C0O A;  2GSB A;  1O46 A;  4XZ1 A;  4H34 A;  1YVL A;  2AOA A;  2LRA A;  4M4Z A;  1O48 A;  2MRK A;  5EEQ A;  3OB2 B;  1O4B A;  1O4I A;  1O45 A;  4XZ0 A;  1OO3 A;  3VRR A;  1SPS A;  1TZE E;  1X27 A;  1O49 A;  3CXL A;  1FHS A;  1BHH B;  1R1Q A;  3N8M A;  1JWO A;  2DLZ A;  3GQI B;  1CSY A;  3QWY A;  2DLY A;  1O4E A;  4GWF A;  3ZNI A;  3PS5 A;  3KFJ A;  1F2F A;  1LCJ A;  1P13 A;  1O42 A;  1A1E A;  1QCF A;  1AYD A;  1UUS A;  3IMJ A;  1AYA A;  4EIH A;  2JYQ A;  2LQW A;  2DVJ A;  3VRZ A;  2Y1N A;  1O4L A;  1A1B A;  1FBV A;  5EHR A;  5AUL A;  1Z3K A;  3PFV A;  1X0N A;  1BMB A;  2PLE A;  1O4A A;  4OHI A;  3VS2 A;  2ECD A;  1D4T A;  1O4N A;  2CRH A;  1X6C A;  3UF4 A;  4P9Z A;  2H8H A;  2MC1 A;  3IN8 A;  1AOU F;  3MAZ A;  5AXI A;  2DM0 A;  1O43 A;  3LYV A;  3VS1 A;  1JYU A;  1O4J A;  1M61 A;  3HIZ B;  3CWG A;  1BKM A;  2DX0 A;  3IMD A;  2LNX A;  3T04 A;  1O4C A; 
#chains in the Genus database with same CATH homology
 1KA7 A;  1F1W A;  1NZV A;  3HHM B;  1CWE A;  4U17 A;  2KK6 A;  5D0J A;  3WA4 A;  3C7I A;  4K2R A;  3PSK A;  3GXW A;  1A1C A;  4OHE A;  1LUK A;  2SHP A;  3BUX B;  1AYB A;  1CSZ A;  2EO6 A;  2GE9 A;  2MRJ A;  2CR4 A;  5EG3 B;  1O4K A;  2EKX A;  1O41 A;  1FU6 A;  1QG1 E;  1OPL A;  4F59 A;  4JE4 A;  3VRO A;  4LUE A;  2HUW A;  2HDX A;  2EU0 A;  1OO4 A;  1LUI A;  3BUO B;  2QMS A;  5DC4 A;  3MXC A;  1R1P A;  1SHA A;  5I6V A;  3VS5 A;  5IBS A;  1SPR A;  5DC9 A;  4FL2 A;  1BG1 A;  3UYO A;  3VS6 A;  1PIC A;  3VRN A;  2MK2 A;  2DCR A;  4P9V A;  3GXX A;  1B47 A;  3QWX X;  1KSW A;  4F5A A;  1D4W A;  1NZL A;  2SRC A;  2L3T A;  4OHL A;  3HCK A;  3VS3 A;  1BLK A;  2L4K A;  4FBN A;  1HCT B;  3TL0 A;  3OV1 A;  1JYQ A;  1MIL A;  1A09 A;  1HCS B;  1TCE A;  1O4R A;  1LKL A;  1K9A A;  1MW4 A;  4K44 A;  2EL8 A;  2AUG A;  1A08 A;  5GJH A;  2HCK A;  2RMX A;  3VGO A;  3VRQ A;  4K45 A;  1UUR A;  3BUW B;  2Y1M A;  1Y1U A;  1WQU A;  5KAZ A;  3OB1 B;  5GJI A;  2MQI A;  1A07 A;  1O4O A;  1LKK A;  3PJP A;  4K11 A;  1AB2 A;  1LCK A;  5HKY A;  2PNB A;  1AD5 A;  1BHF A;  3BUN B;  2CIA A;  1BFJ A;  2LNW A;  1AOT F;  1KC2 A;  2VIF A;  5IBM A;  2XP1 A;  2EYV A;  3OVE A;  4LUD A;  2AOB A;  2IUH A;  5DC0 B;  4U1P A;  1JYR A;  2PNA A;  1CJ1 A;  4H1O A;  4JEG A;  5HKZ A;  2H46 E;  1FBZ A;  1SHB A;  4F5B A;  1BFI A;  1O4F A;  4WWQ A;  3VS0 A;  2EO3 A;  2CI8 A;  1KA6 A;  4E68 A;  4A4B A;  3BKB A;  1O4H A;  1OPK A;  1LUN A;  1IJR A;  1CWD L;  3EAC A;  1A1A A;  2FO0 A;  1I3Z A;  2PLD A;  3K2M A;  1O4P A;  2H5K A;  3NHN A;  2BBU A;  4D8K A;  1IS0 A;  1O44 A;  3EAZ A;  2B3O A;  4DGX A;  5HKW A;  3US4 A;  4ROJ A;  1H9O A;  1A81 A;  5CDW A;  1LUM A;  3PSJ A;  3N7Y A;  1RQQ C;  4TZI A;  1O47 A;  2L6K A;  2ABL A;  2OZO A;  2CBL A;  5J3X A;  2LQN A;  3OP0 A;  1NRV A;  1SHD A;  2LCT A;  1BKL A;  2RVF A;  2EYZ A;  4E93 A;  4QSY A;  1O4M A;  2FCI A;  2K79 B;  3CD3 A;  5EHP A;  4NWG A;  2HDV A;  2HMH A;  1YVH A;  2ETZ A;  2EOB A;  2IZV A;  2YSX A;  4A4C A;  1ZFP E;  3PQZ A;  4JGH A;  3CBL A;  3IN7 A;  3VRY A;  3S9K A;  1O4D A;  2YU7 A;  4NWF A;  1AYC A;  1SKJ A;  2IUI A;  3S8N A;  1GRI A;  5DF6 A;  4L1B B;  4OHD A;  2CS0 A;  2ROR A;  5BO4 A;  1XA6 A;  4DGP A;  4OHH A;  2C0T A;  1BM2 A;  1D1Z A;  4GL9 E;  2RSY A;  3S8L A;  1R1S A;  2EYY A;  2C9W A;  4FL3 A;  1FYR A;  3S8O A;  1FMK A;  1FU5 A;  2Y3A B;  2C0I A;  1O4Q A;  4X6S A;  3MXY A;  2KNO A;  1G83 A;  1BF5 A;  3M7F A;  1Y57 A;  2CI9 A;  3PLF B;  1RJA A;  1BHH A;  1RPY A;  1QAD A;  1GHU A;  3TKZ A;  1M27 A;  2OQ1 A;  1O4G A;  3BUM B;  2K7A B;  3VRP A;  4EY0 A;  5EEL A;  2PTK A;  3VS4 A;  1BLJ A;  2IUG A;  3N84 A;  4GPL B;  1JU5 A;  3VS7 A;  2C0O A;  2GSB A;  1O46 A;  4XZ1 A;  4H34 A;  1YVL A;  2AOA A;  4M4Z A;  1O48 A;  2MRK A;  5EEQ A;  3OB2 B;  1O4B A;  1O4I A;  1O45 A;  4XZ0 A;  1OO3 A;  3VRR A;  1SPS A;  1TZE E;  1X27 A;  1O49 A;  3CXL A;  1FHS A;  1BHH B;  1R1Q A;  3N8M A;  1JWO A;  2DLZ A;  3GQI B;  1CSY A;  3QWY A;  2DLY A;  1O4E A;  4GWF A;  3ZNI A;  3PS5 A;  3KFJ A;  1F2F A;  1LCJ A;  1P13 A;  1O42 A;  1A1E A;  1QCF A;  1AYD A;  1UUS A;  3IMJ A;  1AYA A;  4EIH A;  2JYQ A;  2LQW A;  2DVJ A;  3VRZ A;  2Y1N A;  1O4L A;  1A1B A;  1FBV A;  5EHR A;  5AUL A;  1Z3K A;  3PFV A;  1X0N A;  1BMB A;  2PLE A;  1O4A A;  4OHI A;  3VS2 A;  2ECD A;  1D4T A;  1O4N A;  2CRH A;  1X6C A;  3UF4 A;  4P9Z A;  2H8H A;  2MC1 A;  3IN8 A;  1AOU F;  3MAZ A;  5AXI A;  2DM0 A;  1O43 A;  3VS1 A;  1JYU A;  1O4J A;  1M61 A;  3HIZ B;  3CWG A;  1BKM A;  2DX0 A;  3IMD A;  2LNX A;  3T04 A;  1O4C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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