4L1B | Genus

Total Genus 104

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	104
sequence length	277
structure length	277
Chain Sequence	MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d006a9e3211b37b140fe883/pdb.gz

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The Resolver thinks Pdb

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Time for openFile(/file/5d006a9e3211b37b140fe883/pdb.gz): 3245 ms

reading 277 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

277 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 59 ms

Adding embedded #jmolscript: select ({0:276});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein/transferase/inhibitor
source organism	Homo sapiens
publication title	Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. pubmed doi rcsb
molecule keywords	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub
total genus	104
structure length	277
sequence length	277
ec nomenclature
pdb deposition date	2013-06-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00017	SH2	SH2 domain
B	PF16454	PI3K_P85_iSH2	Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.505.10	Alpha Beta	2-Layer Sandwich	SHC Adaptor Protein	SH2 domain	4l1bB01

2AOBA 4A4BA 1P13A 1LCKA 1O4LA 1LKKA 1IS0A 3OP0A 1AOUF 5EHRA 1K9AA 3BUNB 1O4IA 2QMSA 4DGPA 1HCSB 1TCEA 4E93A 4NWFA 1O4PA 5EELA 2CI8A 3VS5A 4TZIA 3VRYA 3BUOB 3PQZA 1A1AA 3HHMB 2BBUA 4P9VA 5I6VA 3TKZA 1LUMA 2RVFA 4H1OA 1R1QA 5DC9A 1D4TA 1MW4A 2EO6A 1O4MA 3WA4A 2VIFA 3VS1A 3IN8A 5DC4A 1NZLA 2L6KA 2XP1A 1BM2A 2IUGA 3MXYA 1O4BA 4QSYA 3VS7A 4EIHA 1PICA 3IMDA 1O44A 2H8HA 1I3ZA 1O4DA 2EKXA 2LQWA 1XA6A 2PLDA 1FBVA 1R1PA 2CR4A 2GE9A 1KSWA 1F2FA 2EO3A 2HDVA 2Y1NA 3OVEA 4JEGA 3S8NA 4L1BB 2IUIA 2C0TA 3S8LA 4OHDA 1GRIA 1O4GA 4XZ0A 2H5KA 4GWFA 1LCJA 5HKYA 2B3OA 1X0NA 3UF4A 5EG3B 2EYVA 1LUNA 1Y57A 4K45A 1SHAA 2MC1A 2C0OA 5GJIA 4NWGA 3VS3A 3S9KA 3BUWB 2IUHA 2PNAA 1TZEE 1BHHA 3PSJA 1JU5A 1AD5A 4X6SA 3HIZB 1M27A 1SPRA 1QCFA 1SPSA 4F5BA 1O47A 1O4HA 1AYDA 1CWDL 2PLEA 2RSYA 3EACA 1FYRA 5IBMA 1O4FA 3PSKA 2H46E 2HUWA 2EOBA 2HDXA 4WWQA 2ECDA 4U1PA 1RJAA 1O48A 3VS4A 3VRRA 3N8MA 1O4JA 2EL8A 3PFVA 2HMHA 1NZVA 3QWYA 2DLZA 4DGXA 2LCTA 3PJPA 1FBZA 1A07A 3GQIB 1BLJA 2KK6A 2YU7A 5D0JA 1NRVA 3N7YA 1CWEA 3QWXX 1X27A 2DX0A 1FU5A 1KA7A 4E68A 1Y1UA 2RORA 4FBNA 3CD3A 1D4WA 1H9OA 2KNOA 1UUSA 1OPKA 1QADA 3PS5A 4GPLB 3MAZA 4LUDA 1HCTB 1SHDA 1OO4A 1B47A 1BHHB 1O4QA 4P9ZA 1JYUA 3VS2A 2RMXA 3IMJA 2CRHA 2AUGA 4OHEA 5DC0B 2OQ1A 2L4KA 2ABLA 1YVLA 4F59A 2L3TA 2DM0A 5HKZA 5EEQA 1A81A 4K44A 1O4KA 3VRNA 2CI9A 3TL0A 2PNBA 5J3XA 4K2RA 3PLFB 3ZNIA 1OO3A 3VGOA 1O4NA 1G83A 3UYOA 1LUKA 2K79B 1O49A 5AULA 3HCKA 1AB2A 3OV1A 1BF5A 4H34A 1AOTF 3KFJA 4GL9E 1WQUA 1UURA 1A1BA 4EY0A 1AYBA 3VROA 3VRPA 2MK2A 2OZOA 4U17A 1O46A 3NHNA 3C7IA 4XZ1A 3VRQA 2Y1MA 3MXCA 4A4CA 4K11A 4JE4A 2EYZA 2LQNA 1O41A 2GSBA 2MRKA 4JGHA 2ETZA 2SRCA 5HKWA 1Z3KA 1IJRA 1F1WA 2MRJA 4F5AA 2YSXA 1O42A 3BKBA 2CS0A 4OHIA 4OHLA 1R1SA 1AYAA 3CBLA 1KA6A 2HCKA 2Y3AB 2LNWA 1X6CA 1SKJA 1BHFA 1BFJA 1BMBA 3M7FA 2K7AB 5AXIA 2C9WA 1QG1E 2JYQA 1A1CA 2CBLA 3VRZA 1BLKA 2DLYA 4ROJA 2C0IA 1O4RA 1M61A 3GXWA 3VS0A 3CWGA 2SHPA 1CSZA 2LNXA 1GHUA 5DF6A 1O4CA 4LUEA 1JYQA 1O4EA 2IZVA 1FHSA 3CXLA 3N84A 1JYRA 1LKLA 3OB1B 1ZFPE 3OB2B 1BKMA 2EU0A 4D8KA 4OHHA 1CSYA 3T04A 1RQQC 1SHBA 1RPYA 3BUMB 1O45A 1O4OA 1CJ1A 2FO0A 5EHPA 5CDWA 5BO4A 3EAZA 2FCIA 2DCRA 1FU6A 1FMKA 2MQIA 1MILA 1JWOA 3BUXB 5IBSA 5KAZA 1LUIA 1KC2A 1BFIA 3VS6A 1D1ZA 1AYCA 1YVHA 1BKLA 3S8OA 3GXXA 4FL3A 1A09A 4M4ZA 3IN7A 2EYYA 5GJHA 3K2MA 1A1EA 2DVJA 3US4A 1O4AA 2PTKA 2AOAA 4FL2A 2CIAA 1A08A 1O43A 1OPLA 1BG1A
chains in the Genus database with same CATH superfamily

2AOBA 4A4BA 1P13A 1LCKA 1O4LA 1LKKA 1IS0A 3OP0A 1AOUF 5EHRA 1K9AA 3BUNB 1O4IA 2QMSA 4DGPA 1HCSB 1TCEA 4E93A 4NWFA 1O4PA 5EELA 2CI8A 3VS5A 4TZIA 3VRYA 3BUOB 3PQZA 1A1AA 3HHMB 2BBUA 4P9VA 5I6VA 2LRAA 3TKZA 1LUMA 2RVFA 4H1OA 1R1QA 5DC9A 1D4TA 1MW4A 2EO6A 1O4MA 3WA4A 2VIFA 3VS1A 3IN8A 5DC4A 1NZLA 2L6KA 2XP1A 1BM2A 2IUGA 3MXYA 1O4BA 4QSYA 3VS7A 4EIHA 1PICA 3IMDA 1O44A 2H8HA 1I3ZA 1O4DA 2EKXA 2LQWA 1XA6A 2PLDA 1FBVA 1R1PA 2CR4A 2GE9A 1KSWA 1F2FA 2EO3A 2HDVA 2Y1NA 3OVEA 4JEGA 3S8NA 4L1BB 2IUIA 2C0TA 3S8LA 4OHDA 1GRIA 1O4GA 4XZ0A 2H5KA 4GWFA 1LCJA 5HKYA 2B3OA 1X0NA 3UF4A 5EG3B 2EYVA 1LUNA 1Y57A 4K45A 1SHAA 2MC1A 2C0OA 5GJIA 4NWGA 3VS3A 3S9KA 3BUWB 2IUHA 2PNAA 1TZEE 1BHHA 3PSJA 1JU5A 1AD5A 4X6SA 3HIZB 1M27A 1SPRA 1QCFA 1SPSA 4F5BA 1O47A 1O4HA 1AYDA 1CWDL 2PLEA 2RSYA 3EACA 1FYRA 5IBMA 1O4FA 3PSKA 2H46E 2HUWA 2EOBA 2HDXA 4WWQA 2ECDA 4U1PA 1RJAA 1O48A 3VS4A 3VRRA 3N8MA 1O4JA 2EL8A 3PFVA 2HMHA 1NZVA 3QWYA 2DLZA 4DGXA 2LCTA 3PJPA 1FBZA 1A07A 3GQIB 1BLJA 3LYVA 2KK6A 2YU7A 5D0JA 1NRVA 3N7YA 1CWEA 3QWXX 1X27A 2DX0A 1FU5A 1KA7A 4E68A 1Y1UA 2RORA 4FBNA 3CD3A 1D4WA 1H9OA 2KNOA 1UUSA 1OPKA 1QADA 3PS5A 4GPLB 3MAZA 4LUDA 1HCTB 1SHDA 1OO4A 1B47A 1BHHB 1O4QA 4P9ZA 1JYUA 3VS2A 2RMXA 3IMJA 2CRHA 2AUGA 4OHEA 5DC0B 2OQ1A 2L4KA 2ABLA 1YVLA 4F59A 2L3TA 2DM0A 5HKZA 5EEQA 1A81A 4K44A 1O4KA 3K2TA 3VRNA 2CI9A 3TL0A 2PNBA 5J3XA 4K2RA 3PLFB 3ZNIA 1OO3A 3VGOA 1O4NA 1G83A 3UYOA 1LUKA 2K79B 1O49A 5AULA 3HCKA 1AB2A 3OV1A 1BF5A 4H34A 1AOTF 3KFJA 4GL9E 1WQUA 1UURA 1A1BA 4EY0A 1AYBA 3VROA 3VRPA 2MK2A 2OZOA 4U17A 1O46A 3NHNA 3C7IA 4XZ1A 3VRQA 2Y1MA 3MXCA 4A4CA 4K11A 4JE4A 2EYZA 2LQNA 1O41A 2GSBA 2MRKA 4JGHA 2ETZA 2SRCA 5HKWA 1Z3KA 1IJRA 1F1WA 2MRJA 4F5AA 2YSXA 1O42A 3BKBA 2CS0A 4OHIA 4OHLA 1R1SA 1AYAA 3CBLA 1KA6A 2HCKA 2Y3AB 2LNWA 1X6CA 1SKJA 1BHFA 1BFJA 1BMBA 3M7FA 2K7AB 5AXIA 2C9WA 1QG1E 2JYQA 1A1CA 2CBLA 3VRZA 1BLKA 2DLYA 4ROJA 2C0IA 1O4RA 1M61A 3GXWA 3VS0A 3CWGA 2SHPA 1CSZA 2LNXA 1GHUA 5DF6A 1O4CA 4LUEA 1JYQA 1O4EA 2IZVA 1FHSA 3CXLA 3N84A 1JYRA 1LKLA 3OB1B 1ZFPE 3OB2B 1BKMA 2EU0A 4D8KA 4OHHA 1CSYA 3T04A 1RQQC 1SHBA 1RPYA 3BUMB 1O45A 1O4OA 1CJ1A 2FO0A 5EHPA 5CDWA 5BO4A 3EAZA 2FCIA 2DCRA 1FU6A 1FMKA 2MQIA 1MILA 1JWOA 3BUXB 5IBSA 5KAZA 1LUIA 1KC2A 1BFIA 3VS6A 1D1ZA 1AYCA 1YVHA 1BKLA 3S8OA 3GXXA 4FL3A 1A09A 4M4ZA 3IN7A 2EYYA 5GJHA 3K2MA 1A1EA 2DVJA 3US4A 1O4AA 2PTKA 2AOAA 4FL2A 2CIAA 1A08A 2KGYA 1O43A 1OPLA 1BG1A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2AOB A;  4A4B A;  1P13 A;  1LCK A;  1O4L A;  1LKK A;  1IS0 A;  3OP0 A;  1AOU F;  5EHR A;  1K9A A;  3BUN B;  1O4I A;  2QMS A;  4DGP A;  1HCS B;  1TCE A;  4E93 A;  4NWF A;  1O4P A;  5EEL A;  2CI8 A;  3VS5 A;  4TZI A;  3VRY A;  3BUO B;  3PQZ A;  1A1A A;  3HHM B;  2BBU A;  4P9V A;  5I6V A;  3TKZ A;  1LUM A;  2RVF A;  4H1O A;  1R1Q A;  5DC9 A;  1D4T A;  1MW4 A;  2EO6 A;  1O4M A;  3WA4 A;  2VIF A;  3VS1 A;  3IN8 A;  5DC4 A;  1NZL A;  2L6K A;  2XP1 A;  1BM2 A;  2IUG A;  3MXY A;  1O4B A;  4QSY A;  3VS7 A;  4EIH A;  1PIC A;  3IMD A;  1O44 A;  2H8H A;  1I3Z A;  1O4D A;  2EKX A;  2LQW A;  1XA6 A;  2PLD A;  1FBV A;  1R1P A;  2CR4 A;  2GE9 A;  1KSW A;  1F2F A;  2EO3 A;  2HDV A;  2Y1N A;  3OVE A;  4JEG A;  3S8N A;  4L1B B;  2IUI A;  2C0T A;  3S8L A;  4OHD A;  1GRI A;  1O4G A;  4XZ0 A;  2H5K A;  4GWF A;  1LCJ A;  5HKY A;  2B3O A;  1X0N A;  3UF4 A;  5EG3 B;  2EYV A;  1LUN A;  1Y57 A;  4K45 A;  1SHA A;  2MC1 A;  2C0O A;  5GJI A;  4NWG A;  3VS3 A;  3S9K A;  3BUW B;  2IUH A;  2PNA A;  1TZE E;  1BHH A;  3PSJ A;  1JU5 A;  1AD5 A;  4X6S A;  3HIZ B;  1M27 A;  1SPR A;  1QCF A;  1SPS A;  4F5B A;  1O47 A;  1O4H A;  1AYD A;  1CWD L;  2PLE A;  2RSY A;  3EAC A;  1FYR A;  5IBM A;  1O4F A;  3PSK A;  2H46 E;  2HUW A;  2EOB A;  2HDX A;  4WWQ A;  2ECD A;  4U1P A;  1RJA A;  1O48 A;  3VS4 A;  3VRR A;  3N8M A;  1O4J A;  2EL8 A;  3PFV A;  2HMH A;  1NZV A;  3QWY A;  2DLZ A;  4DGX A;  2LCT A;  3PJP A;  1FBZ A;  1A07 A;  3GQI B;  1BLJ A;  2KK6 A;  2YU7 A;  5D0J A;  1NRV A;  3N7Y A;  1CWE A;  3QWX X;  1X27 A;  2DX0 A;  1FU5 A;  1KA7 A;  4E68 A;  1Y1U A;  2ROR A;  4FBN A;  3CD3 A;  1D4W A;  1H9O A;  2KNO A;  1UUS A;  1OPK A;  1QAD A;  3PS5 A;  4GPL B;  3MAZ A;  4LUD A;  1HCT B;  1SHD A;  1OO4 A;  1B47 A;  1BHH B;  1O4Q A;  4P9Z A;  1JYU A;  3VS2 A;  2RMX A;  3IMJ A;  2CRH A;  2AUG A;  4OHE A;  5DC0 B;  2OQ1 A;  2L4K A;  2ABL A;  1YVL A;  4F59 A;  2L3T A;  2DM0 A;  5HKZ A;  5EEQ A;  1A81 A;  4K44 A;  1O4K A;  3VRN A;  2CI9 A;  3TL0 A;  2PNB A;  5J3X A;  4K2R A;  3PLF B;  3ZNI A;  1OO3 A;  3VGO A;  1O4N A;  1G83 A;  3UYO A;  1LUK A;  2K79 B;  1O49 A;  5AUL A;  3HCK A;  1AB2 A;  3OV1 A;  1BF5 A;  4H34 A;  1AOT F;  3KFJ A;  4GL9 E;  1WQU A;  1UUR A;  1A1B A;  4EY0 A;  1AYB A;  3VRO A;  3VRP A;  2MK2 A;  2OZO A;  4U17 A;  1O46 A;  3NHN A;  3C7I A;  4XZ1 A;  3VRQ A;  2Y1M A;  3MXC A;  4A4C A;  4K11 A;  4JE4 A;  2EYZ A;  2LQN A;  1O41 A;  2GSB A;  2MRK A;  4JGH A;  2ETZ A;  2SRC A;  5HKW A;  1Z3K A;  1IJR A;  1F1W A;  2MRJ A;  4F5A A;  2YSX A;  1O42 A;  3BKB A;  2CS0 A;  4OHI A;  4OHL A;  1R1S A;  1AYA A;  3CBL A;  1KA6 A;  2HCK A;  2Y3A B;  2LNW A;  1X6C A;  1SKJ A;  1BHF A;  1BFJ A;  1BMB A;  3M7F A;  2K7A B;  5AXI A;  2C9W A;  1QG1 E;  2JYQ A;  1A1C A;  2CBL A;  3VRZ A;  1BLK A;  2DLY A;  4ROJ A;  2C0I A;  1O4R A;  1M61 A;  3GXW A;  3VS0 A;  3CWG A;  2SHP A;  1CSZ A;  2LNX A;  1GHU A;  5DF6 A;  1O4C A;  4LUE A;  1JYQ A;  1O4E A;  2IZV A;  1FHS A;  3CXL A;  3N84 A;  1JYR A;  1LKL A;  3OB1 B;  1ZFP E;  3OB2 B;  1BKM A;  2EU0 A;  4D8K A;  4OHH A;  1CSY A;  3T04 A;  1RQQ C;  1SHB A;  1RPY A;  3BUM B;  1O45 A;  1O4O A;  1CJ1 A;  2FO0 A;  5EHP A;  5CDW A;  5BO4 A;  3EAZ A;  2FCI A;  2DCR A;  1FU6 A;  1FMK A;  2MQI A;  1MIL A;  1JWO A;  3BUX B;  5IBS A;  5KAZ A;  1LUI A;  1KC2 A;  1BFI A;  3VS6 A;  1D1Z A;  1AYC A;  1YVH A;  1BKL A;  3S8O A;  3GXX A;  4FL3 A;  1A09 A;  4M4Z A;  3IN7 A;  2EYY A;  5GJH A;  3K2M A;  1A1E A;  2DVJ A;  3US4 A;  1O4A A;  2PTK A;  2AOA A;  4FL2 A;  2CIA A;  1A08 A;  1O43 A;  1OPL A;  1BG1 A; 
#chains in the Genus database with same CATH topology
 2AOB A;  4A4B A;  1P13 A;  1LCK A;  1O4L A;  1LKK A;  1IS0 A;  3OP0 A;  1AOU F;  5EHR A;  1K9A A;  3BUN B;  1O4I A;  2QMS A;  4DGP A;  1HCS B;  1TCE A;  4E93 A;  4NWF A;  1O4P A;  5EEL A;  2CI8 A;  3VS5 A;  4TZI A;  3VRY A;  3BUO B;  3PQZ A;  1A1A A;  3HHM B;  2BBU A;  4P9V A;  5I6V A;  2LRA A;  3TKZ A;  1LUM A;  2RVF A;  4H1O A;  1R1Q A;  5DC9 A;  1D4T A;  1MW4 A;  2EO6 A;  1O4M A;  3WA4 A;  2VIF A;  3VS1 A;  3IN8 A;  5DC4 A;  1NZL A;  2L6K A;  2XP1 A;  1BM2 A;  2IUG A;  3MXY A;  1O4B A;  4QSY A;  3VS7 A;  4EIH A;  1PIC A;  3IMD A;  1O44 A;  2H8H A;  1I3Z A;  1O4D A;  2EKX A;  2LQW A;  1XA6 A;  2PLD A;  1FBV A;  1R1P A;  2CR4 A;  2GE9 A;  1KSW A;  1F2F A;  2EO3 A;  2HDV A;  2Y1N A;  3OVE A;  4JEG A;  3S8N A;  4L1B B;  2IUI A;  2C0T A;  3S8L A;  4OHD A;  1GRI A;  1O4G A;  4XZ0 A;  2H5K A;  4GWF A;  1LCJ A;  5HKY A;  2B3O A;  1X0N A;  3UF4 A;  5EG3 B;  2EYV A;  1LUN A;  1Y57 A;  4K45 A;  1SHA A;  2MC1 A;  2C0O A;  5GJI A;  4NWG A;  3VS3 A;  3S9K A;  3BUW B;  2IUH A;  2PNA A;  1TZE E;  1BHH A;  3PSJ A;  1JU5 A;  1AD5 A;  4X6S A;  3HIZ B;  1M27 A;  1SPR A;  1QCF A;  1SPS A;  4F5B A;  1O47 A;  1O4H A;  1AYD A;  1CWD L;  2PLE A;  2RSY A;  3EAC A;  1FYR A;  5IBM A;  1O4F A;  3PSK A;  2H46 E;  2HUW A;  2EOB A;  2HDX A;  4WWQ A;  2ECD A;  4U1P A;  1RJA A;  1O48 A;  3VS4 A;  3VRR A;  3N8M A;  1O4J A;  2EL8 A;  3PFV A;  2HMH A;  1NZV A;  3QWY A;  2DLZ A;  4DGX A;  2LCT A;  3PJP A;  1FBZ A;  1A07 A;  3GQI B;  1BLJ A;  3LYV A;  2KK6 A;  2YU7 A;  5D0J A;  1NRV A;  3N7Y A;  1CWE A;  3QWX X;  1X27 A;  2DX0 A;  1FU5 A;  1KA7 A;  4E68 A;  1Y1U A;  2ROR A;  4FBN A;  3CD3 A;  1D4W A;  1H9O A;  2KNO A;  1UUS A;  1OPK A;  1QAD A;  3PS5 A;  4GPL B;  3MAZ A;  4LUD A;  1HCT B;  1SHD A;  1OO4 A;  1B47 A;  1BHH B;  1O4Q A;  4P9Z A;  1JYU A;  3VS2 A;  2RMX A;  3IMJ A;  2CRH A;  2AUG A;  4OHE A;  5DC0 B;  2OQ1 A;  2L4K A;  2ABL A;  1YVL A;  4F59 A;  2L3T A;  2DM0 A;  5HKZ A;  5EEQ A;  1A81 A;  4K44 A;  1O4K A;  3K2T A;  3VRN A;  2CI9 A;  3TL0 A;  2PNB A;  5J3X A;  4K2R A;  3PLF B;  3ZNI A;  1OO3 A;  3VGO A;  1O4N A;  1G83 A;  3UYO A;  1LUK A;  2K79 B;  1O49 A;  5AUL A;  3HCK A;  1AB2 A;  3OV1 A;  1BF5 A;  4H34 A;  1AOT F;  3KFJ A;  4GL9 E;  1WQU A;  1UUR A;  1A1B A;  4EY0 A;  1AYB A;  3VRO A;  3VRP A;  2MK2 A;  2OZO A;  4U17 A;  1O46 A;  3NHN A;  3C7I A;  4XZ1 A;  3VRQ A;  2Y1M A;  3MXC A;  4A4C A;  4K11 A;  4JE4 A;  2EYZ A;  2LQN A;  1O41 A;  2GSB A;  2MRK A;  4JGH A;  2ETZ A;  2SRC A;  5HKW A;  1Z3K A;  1IJR A;  1F1W A;  2MRJ A;  4F5A A;  2YSX A;  1O42 A;  3BKB A;  2CS0 A;  4OHI A;  4OHL A;  1R1S A;  1AYA A;  3CBL A;  1KA6 A;  2HCK A;  2Y3A B;  2LNW A;  1X6C A;  1SKJ A;  1BHF A;  1BFJ A;  1BMB A;  3M7F A;  2K7A B;  5AXI A;  2C9W A;  1QG1 E;  2JYQ A;  1A1C A;  2CBL A;  3VRZ A;  1BLK A;  2DLY A;  4ROJ A;  2C0I A;  1O4R A;  1M61 A;  3GXW A;  3VS0 A;  3CWG A;  2SHP A;  1CSZ A;  2LNX A;  1GHU A;  5DF6 A;  1O4C A;  4LUE A;  1JYQ A;  1O4E A;  2IZV A;  1FHS A;  3CXL A;  3N84 A;  1JYR A;  1LKL A;  3OB1 B;  1ZFP E;  3OB2 B;  1BKM A;  2EU0 A;  4D8K A;  4OHH A;  1CSY A;  3T04 A;  1RQQ C;  1SHB A;  1RPY A;  3BUM B;  1O45 A;  1O4O A;  1CJ1 A;  2FO0 A;  5EHP A;  5CDW A;  5BO4 A;  3EAZ A;  2FCI A;  2DCR A;  1FU6 A;  1FMK A;  2MQI A;  1MIL A;  1JWO A;  3BUX B;  5IBS A;  5KAZ A;  1LUI A;  1KC2 A;  1BFI A;  3VS6 A;  1D1Z A;  1AYC A;  1YVH A;  1BKL A;  3S8O A;  3GXX A;  4FL3 A;  1A09 A;  4M4Z A;  3IN7 A;  2EYY A;  5GJH A;  3K2M A;  1A1E A;  2DVJ A;  3US4 A;  1O4A A;  2PTK A;  2AOA A;  4FL2 A;  2CIA A;  1A08 A;  2KGY A;  1O43 A;  1OPL A;  1BG1 A; 
#chains in the Genus database with same CATH homology
 2AOB A;  4A4B A;  1P13 A;  1LCK A;  1O4L A;  1LKK A;  1IS0 A;  3OP0 A;  1AOU F;  5EHR A;  1K9A A;  3BUN B;  1O4I A;  2QMS A;  4DGP A;  1HCS B;  1TCE A;  4E93 A;  4NWF A;  1O4P A;  5EEL A;  2CI8 A;  3VS5 A;  4TZI A;  3VRY A;  3BUO B;  3PQZ A;  1A1A A;  3HHM B;  2BBU A;  4P9V A;  5I6V A;  3TKZ A;  1LUM A;  2RVF A;  4H1O A;  1R1Q A;  5DC9 A;  1D4T A;  1MW4 A;  2EO6 A;  1O4M A;  3WA4 A;  2VIF A;  3VS1 A;  3IN8 A;  5DC4 A;  1NZL A;  2L6K A;  2XP1 A;  1BM2 A;  2IUG A;  3MXY A;  1O4B A;  4QSY A;  3VS7 A;  4EIH A;  1PIC A;  3IMD A;  1O44 A;  2H8H A;  1I3Z A;  1O4D A;  2EKX A;  2LQW A;  1XA6 A;  2PLD A;  1FBV A;  1R1P A;  2CR4 A;  2GE9 A;  1KSW A;  1F2F A;  2EO3 A;  2HDV A;  2Y1N A;  3OVE A;  4JEG A;  3S8N A;  4L1B B;  2IUI A;  2C0T A;  3S8L A;  4OHD A;  1GRI A;  1O4G A;  4XZ0 A;  2H5K A;  4GWF A;  1LCJ A;  5HKY A;  2B3O A;  1X0N A;  3UF4 A;  5EG3 B;  2EYV A;  1LUN A;  1Y57 A;  4K45 A;  1SHA A;  2MC1 A;  2C0O A;  5GJI A;  4NWG A;  3VS3 A;  3S9K A;  3BUW B;  2IUH A;  2PNA A;  1TZE E;  1BHH A;  3PSJ A;  1JU5 A;  1AD5 A;  4X6S A;  3HIZ B;  1M27 A;  1SPR A;  1QCF A;  1SPS A;  4F5B A;  1O47 A;  1O4H A;  1AYD A;  1CWD L;  2PLE A;  2RSY A;  3EAC A;  1FYR A;  5IBM A;  1O4F A;  3PSK A;  2H46 E;  2HUW A;  2EOB A;  2HDX A;  4WWQ A;  2ECD A;  4U1P A;  1RJA A;  1O48 A;  3VS4 A;  3VRR A;  3N8M A;  1O4J A;  2EL8 A;  3PFV A;  2HMH A;  1NZV A;  3QWY A;  2DLZ A;  4DGX A;  2LCT A;  3PJP A;  1FBZ A;  1A07 A;  3GQI B;  1BLJ A;  2KK6 A;  2YU7 A;  5D0J A;  1NRV A;  3N7Y A;  1CWE A;  3QWX X;  1X27 A;  2DX0 A;  1FU5 A;  1KA7 A;  4E68 A;  1Y1U A;  2ROR A;  4FBN A;  3CD3 A;  1D4W A;  1H9O A;  2KNO A;  1UUS A;  1OPK A;  1QAD A;  3PS5 A;  4GPL B;  3MAZ A;  4LUD A;  1HCT B;  1SHD A;  1OO4 A;  1B47 A;  1BHH B;  1O4Q A;  4P9Z A;  1JYU A;  3VS2 A;  2RMX A;  3IMJ A;  2CRH A;  2AUG A;  4OHE A;  5DC0 B;  2OQ1 A;  2L4K A;  2ABL A;  1YVL A;  4F59 A;  2L3T A;  2DM0 A;  5HKZ A;  5EEQ A;  1A81 A;  4K44 A;  1O4K A;  3VRN A;  2CI9 A;  3TL0 A;  2PNB A;  5J3X A;  4K2R A;  3PLF B;  3ZNI A;  1OO3 A;  3VGO A;  1O4N A;  1G83 A;  3UYO A;  1LUK A;  2K79 B;  1O49 A;  5AUL A;  3HCK A;  1AB2 A;  3OV1 A;  1BF5 A;  4H34 A;  1AOT F;  3KFJ A;  4GL9 E;  1WQU A;  1UUR A;  1A1B A;  4EY0 A;  1AYB A;  3VRO A;  3VRP A;  2MK2 A;  2OZO A;  4U17 A;  1O46 A;  3NHN A;  3C7I A;  4XZ1 A;  3VRQ A;  2Y1M A;  3MXC A;  4A4C A;  4K11 A;  4JE4 A;  2EYZ A;  2LQN A;  1O41 A;  2GSB A;  2MRK A;  4JGH A;  2ETZ A;  2SRC A;  5HKW A;  1Z3K A;  1IJR A;  1F1W A;  2MRJ A;  4F5A A;  2YSX A;  1O42 A;  3BKB A;  2CS0 A;  4OHI A;  4OHL A;  1R1S A;  1AYA A;  3CBL A;  1KA6 A;  2HCK A;  2Y3A B;  2LNW A;  1X6C A;  1SKJ A;  1BHF A;  1BFJ A;  1BMB A;  3M7F A;  2K7A B;  5AXI A;  2C9W A;  1QG1 E;  2JYQ A;  1A1C A;  2CBL A;  3VRZ A;  1BLK A;  2DLY A;  4ROJ A;  2C0I A;  1O4R A;  1M61 A;  3GXW A;  3VS0 A;  3CWG A;  2SHP A;  1CSZ A;  2LNX A;  1GHU A;  5DF6 A;  1O4C A;  4LUE A;  1JYQ A;  1O4E A;  2IZV A;  1FHS A;  3CXL A;  3N84 A;  1JYR A;  1LKL A;  3OB1 B;  1ZFP E;  3OB2 B;  1BKM A;  2EU0 A;  4D8K A;  4OHH A;  1CSY A;  3T04 A;  1RQQ C;  1SHB A;  1RPY A;  3BUM B;  1O45 A;  1O4O A;  1CJ1 A;  2FO0 A;  5EHP A;  5CDW A;  5BO4 A;  3EAZ A;  2FCI A;  2DCR A;  1FU6 A;  1FMK A;  2MQI A;  1MIL A;  1JWO A;  3BUX B;  5IBS A;  5KAZ A;  1LUI A;  1KC2 A;  1BFI A;  3VS6 A;  1D1Z A;  1AYC A;  1YVH A;  1BKL A;  3S8O A;  3GXX A;  4FL3 A;  1A09 A;  4M4Z A;  3IN7 A;  2EYY A;  5GJH A;  3K2M A;  1A1E A;  2DVJ A;  3US4 A;  1O4A A;  2PTK A;  2AOA A;  4FL2 A;  2CIA A;  1A08 A;  1O43 A;  1OPL A;  1BG1 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4L1BB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations