4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 7
molecule tags Signaling protein
source organism Homo sapiens
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
2C0OA 5D0JA 2LCTA 4GL9E 1RJAA 1BHFA 1BHHB 3EAZA 1BKMA 2L3TA 3VS0A 1SHDA 1K9AA 4DGPA 3VS6A 1MILA 1KC2A 3OP0A 1BFJA 1BLKA 2PNBA 4OHLA 1R1PA 2Y1NA 3CXLA 4OHEA 1O4DA 1BM2A 3OVEA 4H1OA 4XZ0A 3QWYA 4A4CA 1TZEE 4GWFA 2FO0A 1NZVA 1O42A 1JYUA 1Y1UA 4F59A 1FYRA 1AOUF 5HKZA 3GXWA 2RORA 1AYBA 3PSJA 1AYAA 2RSYA 2IZVA 5EELA 1LUKA 1LCKA 2VIFA 4M4ZA 4U17A 1A09A 3OV1A 1Z3KA 2HDVA 4DGXA 3HHMB 2JYQA 2MRKA 3N7YA 1YVLA 3HIZB 1I3ZA 2DLYA 1O4AA 1BMBA 1SPRA 3IN8A 2CIAA 1KA6A 2IUIA 1O4JA 4U1PA 2KNOA 1G83A 1R1SA 3VRYA 3S8OA 2MC1A 1UUSA 2IUHA 2IUGA 3PLFB 2LQNA 1AD5A 1JU5A 1O4HA 1FBVA 1O4RA 2GE9A 1B47A 1OPKA 2EL8A 4TZIA 3UF4A 5EHRA 2HDXA 4K11A 3MXCA 3PSKA 1OO4A 2EYZA 1BHHA 4ROJA 4P9ZA 1R1QA 1FHSA 1LKLA 4EY0A 2AUGA 1JYRA 1O4IA 1CSZA 3PS5A 2EKXA 4QSYA 1FMKA 3K2MA 2H46E 1M61A 3VS2A 1LUIA 2CS0A 3TL0A 1IJRA 2LQWA 2C0TA 5KAZA 4FL2A 3ZNIA 4A4BA 3BUOB 3S9KA 1CWEA 2Y1MA 3VS1A 1O49A 5EHPA 3C7IA 1SKJA 2YSXA 3BUNB 1D4TA 1O4GA 2HCKA 3BKBA 1A1EA 1A81A 2RMXA 1HCTB 4E68A 3S8NA 2ABLA 1O4KA 3IMJA 1F2FA 4F5AA 3GQIB 1O44A 4GPLB 1O45A 1Y57A 1FBZA 3KFJA 2BBUA 5HKYA 3PQZA 2KK6A 1BFIA 1JWOA 3CBLA 1HCSB 3N8MA 2AOAA 2CI8A 1AYDA 1CWDL 2K7AB 2SRCA 2EOBA 5GJHA 3PFVA 4LUEA 4K45A 4K44A 2ECDA 1M27A 3VS3A 3VROA 1SPSA 1D1ZA 4L1BB 3CD3A 2L4KA 3UYOA 1GRIA 2HUWA 1O4FA 2LNXA 2PLDA 1LUMA 5CDWA 1RQQC 3NHNA 1SHBA 3OB1B 2EYVA 2YU7A 2LNWA 3VGOA 1O46A 1GHUA 1NZLA 2CR4A 5IBSA 5I6VA 1BF5A 1FU6A 4NWFA 3EACA 1O4BA 4JEGA 4JGHA 3VRZA 5J3XA 1ZFPE 4OHDA 3IMDA 3OB2B 3VS4A 2XP1A 2DM0A 4H34A 1AB2A 1X6CA 1KSWA 1MW4A 2L6KA 4E93A 3IN7A 2GSBA 3VRQA 1YVHA 1FU5A 1QCFA 1O4PA 1NRVA 3HCKA 3PJPA 2OZOA 2EO3A 1CSYA 2DCRA 5AXIA 2MQIA 3VS5A 1X0NA 3BUWB 1BKLA 2FCIA 2OQ1A 1O4MA 1AYCA 1O4LA 1O43A 4X6SA 5BO4A 4P9VA 2CRHA 1A07A 1O4CA 2CI9A 5EEQA 2PTKA 1LCJA 5DC0B 4FL3A 5DC4A 2RVFA 2PNAA 1WQUA 3WA4A 1A1BA 2C0IA 2EO6A 3VRNA 1XA6A 2DLZA 1KA7A 3N84A 4EIHA 1CJ1A 2ETZA 3BUXB 3VRRA 4FBNA 1SHAA 4LUDA 2B3OA 2CBLA 1OPLA 3VS7A 2MRJA 1BG1A 3S8LA 1O48A 1UURA 1RPYA 3T04A 3VRPA 1LKKA 2SHPA 1O47A 1LUNA 1P13A 5GJIA 1O4OA 5IBMA 1O4EA 2AOBA 5HKWA 1BLJA 4F5BA 1JYQA 3CWGA 4WWQA 4JE4A 2PLEA 4K2RA 3MXYA 3MAZA 2H5KA 5DC9A 1A1AA 4D8KA 2DVJA 2EYYA 2EU0A 5DF6A 1PICA 4XZ1A 4NWGA 2HMHA 1A08A 3QWXX 1IS0A 1A1CA 2DX0A 2QMSA 2Y3AB 1QG1E 1H9OA 1QADA 1F1WA 1OO3A 1X27A 3BUMB 3TKZA 4OHIA 3US4A 1AOTF 3M7FA 4OHHA 1O41A 1O4NA 3GXXA 2C9WA 5AULA 2MK2A 5EG3B 2K79B 1O4QA 1D4WA 1TCEA 2H8HA
chains in the Genus database with same CATH superfamily
2C0OA 5D0JA 2LCTA 4GL9E 1RJAA 1BHFA 1BHHB 3EAZA 1BKMA 2L3TA 3VS0A 1SHDA 1K9AA 4DGPA 3VS6A 1MILA 1KC2A 3OP0A 1BFJA 1BLKA 2PNBA 4OHLA 1R1PA 2Y1NA 3CXLA 4OHEA 1O4DA 1BM2A 3OVEA 4H1OA 4XZ0A 3QWYA 4A4CA 1TZEE 4GWFA 2FO0A 1NZVA 1O42A 1JYUA 1Y1UA 4F59A 1FYRA 1AOUF 5HKZA 3GXWA 2RORA 1AYBA 3PSJA 1AYAA 2RSYA 2IZVA 5EELA 1LUKA 1LCKA 2VIFA 4M4ZA 4U17A 1A09A 3OV1A 1Z3KA 2HDVA 4DGXA 3HHMB 2JYQA 2MRKA 3N7YA 1YVLA 3HIZB 1I3ZA 2DLYA 1O4AA 1BMBA 1SPRA 3IN8A 2CIAA 1KA6A 3LYVA 2IUIA 1O4JA 4U1PA 2KNOA 1G83A 1R1SA 3VRYA 3S8OA 2MC1A 1UUSA 2IUHA 2IUGA 3PLFB 2LQNA 1AD5A 1JU5A 1O4HA 1FBVA 1O4RA 2GE9A 1B47A 1OPKA 2EL8A 4TZIA 3UF4A 5EHRA 2HDXA 4K11A 3MXCA 3PSKA 1OO4A 2EYZA 1BHHA 4ROJA 4P9ZA 1R1QA 1FHSA 1LKLA 4EY0A 2AUGA 1JYRA 1O4IA 1CSZA 3PS5A 2EKXA 4QSYA 1FMKA 3K2MA 2H46E 1M61A 3VS2A 1LUIA 2CS0A 3TL0A 1IJRA 2LQWA 2C0TA 5KAZA 4FL2A 3ZNIA 4A4BA 2KGYA 3BUOB 3S9KA 1CWEA 3K2TA 2Y1MA 3VS1A 1O49A 5EHPA 3C7IA 1SKJA 2YSXA 3BUNB 1D4TA 1O4GA 2HCKA 3BKBA 1A1EA 1A81A 2RMXA 1HCTB 4E68A 3S8NA 2ABLA 1O4KA 3IMJA 1F2FA 4F5AA 3GQIB 1O44A 4GPLB 1O45A 1Y57A 1FBZA 3KFJA 2BBUA 5HKYA 3PQZA 2KK6A 1BFIA 1JWOA 3CBLA 1HCSB 3N8MA 2AOAA 2CI8A 1AYDA 1CWDL 2K7AB 2SRCA 2EOBA 5GJHA 3PFVA 4LUEA 4K45A 4K44A 2ECDA 1M27A 3VS3A 3VROA 1SPSA 1D1ZA 4L1BB 3CD3A 2L4KA 3UYOA 1GRIA 2HUWA 1O4FA 2LNXA 2PLDA 1LUMA 5CDWA 1RQQC 3NHNA 1SHBA 3OB1B 2EYVA 2YU7A 2LNWA 3VGOA 1O46A 1GHUA 1NZLA 2CR4A 5IBSA 5I6VA 1BF5A 1FU6A 4NWFA 3EACA 1O4BA 4JEGA 4JGHA 3VRZA 5J3XA 1ZFPE 4OHDA 3IMDA 3OB2B 3VS4A 2XP1A 2DM0A 4H34A 1AB2A 1X6CA 1KSWA 1MW4A 2L6KA 4E93A 3IN7A 2GSBA 3VRQA 1YVHA 1FU5A 1QCFA 1O4PA 1NRVA 3HCKA 3PJPA 2OZOA 2EO3A 1CSYA 2DCRA 5AXIA 2MQIA 3VS5A 1X0NA 3BUWB 1BKLA 2FCIA 2OQ1A 1O4MA 1AYCA 1O4LA 1O43A 4X6SA 5BO4A 4P9VA 2CRHA 1A07A 1O4CA 2CI9A 5EEQA 2PTKA 1LCJA 5DC0B 4FL3A 5DC4A 2RVFA 2PNAA 1WQUA 3WA4A 1A1BA 2C0IA 2EO6A 3VRNA 1XA6A 2DLZA 1KA7A 3N84A 4EIHA 1CJ1A 2ETZA 3BUXB 3VRRA 4FBNA 1SHAA 4LUDA 2B3OA 2CBLA 1OPLA 3VS7A 2MRJA 1BG1A 3S8LA 2LRAA 1O48A 1UURA 1RPYA 3T04A 3VRPA 1LKKA 2SHPA 1O47A 1LUNA 1P13A 5GJIA 1O4OA 5IBMA 1O4EA 2AOBA 5HKWA 1BLJA 4F5BA 1JYQA 3CWGA 4WWQA 4JE4A 2PLEA 4K2RA 3MXYA 3MAZA 2H5KA 5DC9A 1A1AA 4D8KA 2DVJA 2EYYA 2EU0A 5DF6A 1PICA 4XZ1A 4NWGA 2HMHA 1A08A 3QWXX 1IS0A 1A1CA 2DX0A 2QMSA 2Y3AB 1QG1E 1H9OA 1QADA 1F1WA 1OO3A 1X27A 3BUMB 3TKZA 4OHIA 3US4A 1AOTF 3M7FA 4OHHA 1O41A 1O4NA 3GXXA 2C9WA 5AULA 2MK2A 5EG3B 2K79B 1O4QA 1D4WA 1TCEA 2H8HA
chains in the Genus database with same CATH topology
2C0OA 5D0JA 2LCTA 4GL9E 1RJAA 1BHFA 1BHHB 3EAZA 1BKMA 2L3TA 3VS0A 1SHDA 1K9AA 4DGPA 3VS6A 1MILA 1KC2A 3OP0A 1BFJA 1BLKA 2PNBA 4OHLA 1R1PA 2Y1NA 3CXLA 4OHEA 1O4DA 1BM2A 3OVEA 4H1OA 4XZ0A 3QWYA 4A4CA 1TZEE 4GWFA 2FO0A 1NZVA 1O42A 1JYUA 1Y1UA 4F59A 1FYRA 1AOUF 5HKZA 3GXWA 2RORA 1AYBA 3PSJA 1AYAA 2RSYA 2IZVA 5EELA 1LUKA 1LCKA 2VIFA 4M4ZA 4U17A 1A09A 3OV1A 1Z3KA 2HDVA 4DGXA 3HHMB 2JYQA 2MRKA 3N7YA 1YVLA 3HIZB 1I3ZA 2DLYA 1O4AA 1BMBA 1SPRA 3IN8A 2CIAA 1KA6A 2IUIA 1O4JA 4U1PA 2KNOA 1G83A 1R1SA 3VRYA 3S8OA 2MC1A 1UUSA 2IUHA 2IUGA 3PLFB 2LQNA 1AD5A 1JU5A 1O4HA 1FBVA 1O4RA 2GE9A 1B47A 1OPKA 2EL8A 4TZIA 3UF4A 5EHRA 2HDXA 4K11A 3MXCA 3PSKA 1OO4A 2EYZA 1BHHA 4ROJA 4P9ZA 1R1QA 1FHSA 1LKLA 4EY0A 2AUGA 1JYRA 1O4IA 1CSZA 3PS5A 2EKXA 4QSYA 1FMKA 3K2MA 2H46E 1M61A 3VS2A 1LUIA 2CS0A 3TL0A 1IJRA 2LQWA 2C0TA 5KAZA 4FL2A 3ZNIA 4A4BA 3BUOB 3S9KA 1CWEA 2Y1MA 3VS1A 1O49A 5EHPA 3C7IA 1SKJA 2YSXA 3BUNB 1D4TA 1O4GA 2HCKA 3BKBA 1A1EA 1A81A 2RMXA 1HCTB 4E68A 3S8NA 2ABLA 1O4KA 3IMJA 1F2FA 4F5AA 3GQIB 1O44A 4GPLB 1O45A 1Y57A 1FBZA 3KFJA 2BBUA 5HKYA 3PQZA 2KK6A 1BFIA 1JWOA 3CBLA 1HCSB 3N8MA 2AOAA 2CI8A 1AYDA 1CWDL 2K7AB 2SRCA 2EOBA 5GJHA 3PFVA 4LUEA 4K45A 4K44A 2ECDA 1M27A 3VS3A 3VROA 1SPSA 1D1ZA 4L1BB 3CD3A 2L4KA 3UYOA 1GRIA 2HUWA 1O4FA 2LNXA 2PLDA 1LUMA 5CDWA 1RQQC 3NHNA 1SHBA 3OB1B 2EYVA 2YU7A 2LNWA 3VGOA 1O46A 1GHUA 1NZLA 2CR4A 5IBSA 5I6VA 1BF5A 1FU6A 4NWFA 3EACA 1O4BA 4JEGA 4JGHA 3VRZA 5J3XA 1ZFPE 4OHDA 3IMDA 3OB2B 3VS4A 2XP1A 2DM0A 4H34A 1AB2A 1X6CA 1KSWA 1MW4A 2L6KA 4E93A 3IN7A 2GSBA 3VRQA 1YVHA 1FU5A 1QCFA 1O4PA 1NRVA 3HCKA 3PJPA 2OZOA 2EO3A 1CSYA 2DCRA 5AXIA 2MQIA 3VS5A 1X0NA 3BUWB 1BKLA 2FCIA 2OQ1A 1O4MA 1AYCA 1O4LA 1O43A 4X6SA 5BO4A 4P9VA 2CRHA 1A07A 1O4CA 2CI9A 5EEQA 2PTKA 1LCJA 5DC0B 4FL3A 5DC4A 2RVFA 2PNAA 1WQUA 3WA4A 1A1BA 2C0IA 2EO6A 3VRNA 1XA6A 2DLZA 1KA7A 3N84A 4EIHA 1CJ1A 2ETZA 3BUXB 3VRRA 4FBNA 1SHAA 4LUDA 2B3OA 2CBLA 1OPLA 3VS7A 2MRJA 1BG1A 3S8LA 1O48A 1UURA 1RPYA 3T04A 3VRPA 1LKKA 2SHPA 1O47A 1LUNA 1P13A 5GJIA 1O4OA 5IBMA 1O4EA 2AOBA 5HKWA 1BLJA 4F5BA 1JYQA 3CWGA 4WWQA 4JE4A 2PLEA 4K2RA 3MXYA 3MAZA 2H5KA 5DC9A 1A1AA 4D8KA 2DVJA 2EYYA 2EU0A 5DF6A 1PICA 4XZ1A 4NWGA 2HMHA 1A08A 3QWXX 1IS0A 1A1CA 2DX0A 2QMSA 2Y3AB 1QG1E 1H9OA 1QADA 1F1WA 1OO3A 1X27A 3BUMB 3TKZA 4OHIA 3US4A 1AOTF 3M7FA 4OHHA 1O41A 1O4NA 3GXXA 2C9WA 5AULA 2MK2A 5EG3B 2K79B 1O4QA 1D4WA 1TCEA 2H8HA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2C0O A;  5D0J A;  2LCT A;  4GL9 E;  1RJA A;  1BHF A;  1BHH B;  3EAZ A;  1BKM A;  2L3T A;  3VS0 A;  1SHD A;  1K9A A;  4DGP A;  3VS6 A;  1MIL A;  1KC2 A;  3OP0 A;  1BFJ A;  1BLK A;  2PNB A;  4OHL A;  1R1P A;  2Y1N A;  3CXL A;  4OHE A;  1O4D A;  1BM2 A;  3OVE A;  4H1O A;  4XZ0 A;  3QWY A;  4A4C A;  1TZE E;  4GWF A;  2FO0 A;  1NZV A;  1O42 A;  1JYU A;  1Y1U A;  4F59 A;  1FYR A;  1AOU F;  5HKZ A;  3GXW A;  2ROR A;  1AYB A;  3PSJ A;  1AYA A;  2RSY A;  2IZV A;  5EEL A;  1LUK A;  1LCK A;  2VIF A;  4M4Z A;  4U17 A;  1A09 A;  3OV1 A;  1Z3K A;  2HDV A;  4DGX A;  3HHM B;  2JYQ A;  2MRK A;  3N7Y A;  1YVL A;  3HIZ B;  1I3Z A;  2DLY A;  1O4A A;  1BMB A;  1SPR A;  3IN8 A;  2CIA A;  1KA6 A;  2IUI A;  1O4J A;  4U1P A;  2KNO A;  1G83 A;  1R1S A;  3VRY A;  3S8O A;  2MC1 A;  1UUS A;  2IUH A;  2IUG A;  3PLF B;  2LQN A;  1AD5 A;  1JU5 A;  1O4H A;  1FBV A;  1O4R A;  2GE9 A;  1B47 A;  1OPK A;  2EL8 A;  4TZI A;  3UF4 A;  5EHR A;  2HDX A;  4K11 A;  3MXC A;  3PSK A;  1OO4 A;  2EYZ A;  1BHH A;  4ROJ A;  4P9Z A;  1R1Q A;  1FHS A;  1LKL A;  4EY0 A;  2AUG A;  1JYR A;  1O4I A;  1CSZ A;  3PS5 A;  2EKX A;  4QSY A;  1FMK A;  3K2M A;  2H46 E;  1M61 A;  3VS2 A;  1LUI A;  2CS0 A;  3TL0 A;  1IJR A;  2LQW A;  2C0T A;  5KAZ A;  4FL2 A;  3ZNI A;  4A4B A;  3BUO B;  3S9K A;  1CWE A;  2Y1M A;  3VS1 A;  1O49 A;  5EHP A;  3C7I A;  1SKJ A;  2YSX A;  3BUN B;  1D4T A;  1O4G A;  2HCK A;  3BKB A;  1A1E A;  1A81 A;  2RMX A;  1HCT B;  4E68 A;  3S8N A;  2ABL A;  1O4K A;  3IMJ A;  1F2F A;  4F5A A;  3GQI B;  1O44 A;  4GPL B;  1O45 A;  1Y57 A;  1FBZ A;  3KFJ A;  2BBU A;  5HKY A;  3PQZ A;  2KK6 A;  1BFI A;  1JWO A;  3CBL A;  1HCS B;  3N8M A;  2AOA A;  2CI8 A;  1AYD A;  1CWD L;  2K7A B;  2SRC A;  2EOB A;  5GJH A;  3PFV A;  4LUE A;  4K45 A;  4K44 A;  2ECD A;  1M27 A;  3VS3 A;  3VRO A;  1SPS A;  1D1Z A;  4L1B B;  3CD3 A;  2L4K A;  3UYO A;  1GRI A;  2HUW A;  1O4F A;  2LNX A;  2PLD A;  1LUM A;  5CDW A;  1RQQ C;  3NHN A;  1SHB A;  3OB1 B;  2EYV A;  2YU7 A;  2LNW A;  3VGO A;  1O46 A;  1GHU A;  1NZL A;  2CR4 A;  5IBS A;  5I6V A;  1BF5 A;  1FU6 A;  4NWF A;  3EAC A;  1O4B A;  4JEG A;  4JGH A;  3VRZ A;  5J3X A;  1ZFP E;  4OHD A;  3IMD A;  3OB2 B;  3VS4 A;  2XP1 A;  2DM0 A;  4H34 A;  1AB2 A;  1X6C A;  1KSW A;  1MW4 A;  2L6K A;  4E93 A;  3IN7 A;  2GSB A;  3VRQ A;  1YVH A;  1FU5 A;  1QCF A;  1O4P A;  1NRV A;  3HCK A;  3PJP A;  2OZO A;  2EO3 A;  1CSY A;  2DCR A;  5AXI A;  2MQI A;  3VS5 A;  1X0N A;  3BUW B;  1BKL A;  2FCI A;  2OQ1 A;  1O4M A;  1AYC A;  1O4L A;  1O43 A;  4X6S A;  5BO4 A;  4P9V A;  2CRH A;  1A07 A;  1O4C A;  2CI9 A;  5EEQ A;  2PTK A;  1LCJ A;  5DC0 B;  4FL3 A;  5DC4 A;  2RVF A;  2PNA A;  1WQU A;  3WA4 A;  1A1B A;  2C0I A;  2EO6 A;  3VRN A;  1XA6 A;  2DLZ A;  1KA7 A;  3N84 A;  4EIH A;  1CJ1 A;  2ETZ A;  3BUX B;  3VRR A;  4FBN A;  1SHA A;  4LUD A;  2B3O A;  2CBL A;  1OPL A;  3VS7 A;  2MRJ A;  1BG1 A;  3S8L A;  1O48 A;  1UUR A;  1RPY A;  3T04 A;  3VRP A;  1LKK A;  2SHP A;  1O47 A;  1LUN A;  1P13 A;  5GJI A;  1O4O A;  5IBM A;  1O4E A;  2AOB A;  5HKW A;  1BLJ A;  4F5B A;  1JYQ A;  3CWG A;  4WWQ A;  4JE4 A;  2PLE A;  4K2R A;  3MXY A;  3MAZ A;  2H5K A;  5DC9 A;  1A1A A;  4D8K A;  2DVJ A;  2EYY A;  2EU0 A;  5DF6 A;  1PIC A;  4XZ1 A;  4NWG A;  2HMH A;  1A08 A;  3QWX X;  1IS0 A;  1A1C A;  2DX0 A;  2QMS A;  2Y3A B;  1QG1 E;  1H9O A;  1QAD A;  1F1W A;  1OO3 A;  1X27 A;  3BUM B;  3TKZ A;  4OHI A;  3US4 A;  1AOT F;  3M7F A;  4OHH A;  1O41 A;  1O4N A;  3GXX A;  2C9W A;  5AUL A;  2MK2 A;  5EG3 B;  2K79 B;  1O4Q A;  1D4W A;  1TCE A;  2H8H A; 
#chains in the Genus database with same CATH topology
 2C0O A;  5D0J A;  2LCT A;  4GL9 E;  1RJA A;  1BHF A;  1BHH B;  3EAZ A;  1BKM A;  2L3T A;  3VS0 A;  1SHD A;  1K9A A;  4DGP A;  3VS6 A;  1MIL A;  1KC2 A;  3OP0 A;  1BFJ A;  1BLK A;  2PNB A;  4OHL A;  1R1P A;  2Y1N A;  3CXL A;  4OHE A;  1O4D A;  1BM2 A;  3OVE A;  4H1O A;  4XZ0 A;  3QWY A;  4A4C A;  1TZE E;  4GWF A;  2FO0 A;  1NZV A;  1O42 A;  1JYU A;  1Y1U A;  4F59 A;  1FYR A;  1AOU F;  5HKZ A;  3GXW A;  2ROR A;  1AYB A;  3PSJ A;  1AYA A;  2RSY A;  2IZV A;  5EEL A;  1LUK A;  1LCK A;  2VIF A;  4M4Z A;  4U17 A;  1A09 A;  3OV1 A;  1Z3K A;  2HDV A;  4DGX A;  3HHM B;  2JYQ A;  2MRK A;  3N7Y A;  1YVL A;  3HIZ B;  1I3Z A;  2DLY A;  1O4A A;  1BMB A;  1SPR A;  3IN8 A;  2CIA A;  1KA6 A;  3LYV A;  2IUI A;  1O4J A;  4U1P A;  2KNO A;  1G83 A;  1R1S A;  3VRY A;  3S8O A;  2MC1 A;  1UUS A;  2IUH A;  2IUG A;  3PLF B;  2LQN A;  1AD5 A;  1JU5 A;  1O4H A;  1FBV A;  1O4R A;  2GE9 A;  1B47 A;  1OPK A;  2EL8 A;  4TZI A;  3UF4 A;  5EHR A;  2HDX A;  4K11 A;  3MXC A;  3PSK A;  1OO4 A;  2EYZ A;  1BHH A;  4ROJ A;  4P9Z A;  1R1Q A;  1FHS A;  1LKL A;  4EY0 A;  2AUG A;  1JYR A;  1O4I A;  1CSZ A;  3PS5 A;  2EKX A;  4QSY A;  1FMK A;  3K2M A;  2H46 E;  1M61 A;  3VS2 A;  1LUI A;  2CS0 A;  3TL0 A;  1IJR A;  2LQW A;  2C0T A;  5KAZ A;  4FL2 A;  3ZNI A;  4A4B A;  2KGY A;  3BUO B;  3S9K A;  1CWE A;  3K2T A;  2Y1M A;  3VS1 A;  1O49 A;  5EHP A;  3C7I A;  1SKJ A;  2YSX A;  3BUN B;  1D4T A;  1O4G A;  2HCK A;  3BKB A;  1A1E A;  1A81 A;  2RMX A;  1HCT B;  4E68 A;  3S8N A;  2ABL A;  1O4K A;  3IMJ A;  1F2F A;  4F5A A;  3GQI B;  1O44 A;  4GPL B;  1O45 A;  1Y57 A;  1FBZ A;  3KFJ A;  2BBU A;  5HKY A;  3PQZ A;  2KK6 A;  1BFI A;  1JWO A;  3CBL A;  1HCS B;  3N8M A;  2AOA A;  2CI8 A;  1AYD A;  1CWD L;  2K7A B;  2SRC A;  2EOB A;  5GJH A;  3PFV A;  4LUE A;  4K45 A;  4K44 A;  2ECD A;  1M27 A;  3VS3 A;  3VRO A;  1SPS A;  1D1Z A;  4L1B B;  3CD3 A;  2L4K A;  3UYO A;  1GRI A;  2HUW A;  1O4F A;  2LNX A;  2PLD A;  1LUM A;  5CDW A;  1RQQ C;  3NHN A;  1SHB A;  3OB1 B;  2EYV A;  2YU7 A;  2LNW A;  3VGO A;  1O46 A;  1GHU A;  1NZL A;  2CR4 A;  5IBS A;  5I6V A;  1BF5 A;  1FU6 A;  4NWF A;  3EAC A;  1O4B A;  4JEG A;  4JGH A;  3VRZ A;  5J3X A;  1ZFP E;  4OHD A;  3IMD A;  3OB2 B;  3VS4 A;  2XP1 A;  2DM0 A;  4H34 A;  1AB2 A;  1X6C A;  1KSW A;  1MW4 A;  2L6K A;  4E93 A;  3IN7 A;  2GSB A;  3VRQ A;  1YVH A;  1FU5 A;  1QCF A;  1O4P A;  1NRV A;  3HCK A;  3PJP A;  2OZO A;  2EO3 A;  1CSY A;  2DCR A;  5AXI A;  2MQI A;  3VS5 A;  1X0N A;  3BUW B;  1BKL A;  2FCI A;  2OQ1 A;  1O4M A;  1AYC A;  1O4L A;  1O43 A;  4X6S A;  5BO4 A;  4P9V A;  2CRH A;  1A07 A;  1O4C A;  2CI9 A;  5EEQ A;  2PTK A;  1LCJ A;  5DC0 B;  4FL3 A;  5DC4 A;  2RVF A;  2PNA A;  1WQU A;  3WA4 A;  1A1B A;  2C0I A;  2EO6 A;  3VRN A;  1XA6 A;  2DLZ A;  1KA7 A;  3N84 A;  4EIH A;  1CJ1 A;  2ETZ A;  3BUX B;  3VRR A;  4FBN A;  1SHA A;  4LUD A;  2B3O A;  2CBL A;  1OPL A;  3VS7 A;  2MRJ A;  1BG1 A;  3S8L A;  2LRA A;  1O48 A;  1UUR A;  1RPY A;  3T04 A;  3VRP A;  1LKK A;  2SHP A;  1O47 A;  1LUN A;  1P13 A;  5GJI A;  1O4O A;  5IBM A;  1O4E A;  2AOB A;  5HKW A;  1BLJ A;  4F5B A;  1JYQ A;  3CWG A;  4WWQ A;  4JE4 A;  2PLE A;  4K2R A;  3MXY A;  3MAZ A;  2H5K A;  5DC9 A;  1A1A A;  4D8K A;  2DVJ A;  2EYY A;  2EU0 A;  5DF6 A;  1PIC A;  4XZ1 A;  4NWG A;  2HMH A;  1A08 A;  3QWX X;  1IS0 A;  1A1C A;  2DX0 A;  2QMS A;  2Y3A B;  1QG1 E;  1H9O A;  1QAD A;  1F1W A;  1OO3 A;  1X27 A;  3BUM B;  3TKZ A;  4OHI A;  3US4 A;  1AOT F;  3M7F A;  4OHH A;  1O41 A;  1O4N A;  3GXX A;  2C9W A;  5AUL A;  2MK2 A;  5EG3 B;  2K79 B;  1O4Q A;  1D4W A;  1TCE A;  2H8H A; 
#chains in the Genus database with same CATH homology
 2C0O A;  5D0J A;  2LCT A;  4GL9 E;  1RJA A;  1BHF A;  1BHH B;  3EAZ A;  1BKM A;  2L3T A;  3VS0 A;  1SHD A;  1K9A A;  4DGP A;  3VS6 A;  1MIL A;  1KC2 A;  3OP0 A;  1BFJ A;  1BLK A;  2PNB A;  4OHL A;  1R1P A;  2Y1N A;  3CXL A;  4OHE A;  1O4D A;  1BM2 A;  3OVE A;  4H1O A;  4XZ0 A;  3QWY A;  4A4C A;  1TZE E;  4GWF A;  2FO0 A;  1NZV A;  1O42 A;  1JYU A;  1Y1U A;  4F59 A;  1FYR A;  1AOU F;  5HKZ A;  3GXW A;  2ROR A;  1AYB A;  3PSJ A;  1AYA A;  2RSY A;  2IZV A;  5EEL A;  1LUK A;  1LCK A;  2VIF A;  4M4Z A;  4U17 A;  1A09 A;  3OV1 A;  1Z3K A;  2HDV A;  4DGX A;  3HHM B;  2JYQ A;  2MRK A;  3N7Y A;  1YVL A;  3HIZ B;  1I3Z A;  2DLY A;  1O4A A;  1BMB A;  1SPR A;  3IN8 A;  2CIA A;  1KA6 A;  2IUI A;  1O4J A;  4U1P A;  2KNO A;  1G83 A;  1R1S A;  3VRY A;  3S8O A;  2MC1 A;  1UUS A;  2IUH A;  2IUG A;  3PLF B;  2LQN A;  1AD5 A;  1JU5 A;  1O4H A;  1FBV A;  1O4R A;  2GE9 A;  1B47 A;  1OPK A;  2EL8 A;  4TZI A;  3UF4 A;  5EHR A;  2HDX A;  4K11 A;  3MXC A;  3PSK A;  1OO4 A;  2EYZ A;  1BHH A;  4ROJ A;  4P9Z A;  1R1Q A;  1FHS A;  1LKL A;  4EY0 A;  2AUG A;  1JYR A;  1O4I A;  1CSZ A;  3PS5 A;  2EKX A;  4QSY A;  1FMK A;  3K2M A;  2H46 E;  1M61 A;  3VS2 A;  1LUI A;  2CS0 A;  3TL0 A;  1IJR A;  2LQW A;  2C0T A;  5KAZ A;  4FL2 A;  3ZNI A;  4A4B A;  3BUO B;  3S9K A;  1CWE A;  2Y1M A;  3VS1 A;  1O49 A;  5EHP A;  3C7I A;  1SKJ A;  2YSX A;  3BUN B;  1D4T A;  1O4G A;  2HCK A;  3BKB A;  1A1E A;  1A81 A;  2RMX A;  1HCT B;  4E68 A;  3S8N A;  2ABL A;  1O4K A;  3IMJ A;  1F2F A;  4F5A A;  3GQI B;  1O44 A;  4GPL B;  1O45 A;  1Y57 A;  1FBZ A;  3KFJ A;  2BBU A;  5HKY A;  3PQZ A;  2KK6 A;  1BFI A;  1JWO A;  3CBL A;  1HCS B;  3N8M A;  2AOA A;  2CI8 A;  1AYD A;  1CWD L;  2K7A B;  2SRC A;  2EOB A;  5GJH A;  3PFV A;  4LUE A;  4K45 A;  4K44 A;  2ECD A;  1M27 A;  3VS3 A;  3VRO A;  1SPS A;  1D1Z A;  4L1B B;  3CD3 A;  2L4K A;  3UYO A;  1GRI A;  2HUW A;  1O4F A;  2LNX A;  2PLD A;  1LUM A;  5CDW A;  1RQQ C;  3NHN A;  1SHB A;  3OB1 B;  2EYV A;  2YU7 A;  2LNW A;  3VGO A;  1O46 A;  1GHU A;  1NZL A;  2CR4 A;  5IBS A;  5I6V A;  1BF5 A;  1FU6 A;  4NWF A;  3EAC A;  1O4B A;  4JEG A;  4JGH A;  3VRZ A;  5J3X A;  1ZFP E;  4OHD A;  3IMD A;  3OB2 B;  3VS4 A;  2XP1 A;  2DM0 A;  4H34 A;  1AB2 A;  1X6C A;  1KSW A;  1MW4 A;  2L6K A;  4E93 A;  3IN7 A;  2GSB A;  3VRQ A;  1YVH A;  1FU5 A;  1QCF A;  1O4P A;  1NRV A;  3HCK A;  3PJP A;  2OZO A;  2EO3 A;  1CSY A;  2DCR A;  5AXI A;  2MQI A;  3VS5 A;  1X0N A;  3BUW B;  1BKL A;  2FCI A;  2OQ1 A;  1O4M A;  1AYC A;  1O4L A;  1O43 A;  4X6S A;  5BO4 A;  4P9V A;  2CRH A;  1A07 A;  1O4C A;  2CI9 A;  5EEQ A;  2PTK A;  1LCJ A;  5DC0 B;  4FL3 A;  5DC4 A;  2RVF A;  2PNA A;  1WQU A;  3WA4 A;  1A1B A;  2C0I A;  2EO6 A;  3VRN A;  1XA6 A;  2DLZ A;  1KA7 A;  3N84 A;  4EIH A;  1CJ1 A;  2ETZ A;  3BUX B;  3VRR A;  4FBN A;  1SHA A;  4LUD A;  2B3O A;  2CBL A;  1OPL A;  3VS7 A;  2MRJ A;  1BG1 A;  3S8L A;  1O48 A;  1UUR A;  1RPY A;  3T04 A;  3VRP A;  1LKK A;  2SHP A;  1O47 A;  1LUN A;  1P13 A;  5GJI A;  1O4O A;  5IBM A;  1O4E A;  2AOB A;  5HKW A;  1BLJ A;  4F5B A;  1JYQ A;  3CWG A;  4WWQ A;  4JE4 A;  2PLE A;  4K2R A;  3MXY A;  3MAZ A;  2H5K A;  5DC9 A;  1A1A A;  4D8K A;  2DVJ A;  2EYY A;  2EU0 A;  5DF6 A;  1PIC A;  4XZ1 A;  4NWG A;  2HMH A;  1A08 A;  3QWX X;  1IS0 A;  1A1C A;  2DX0 A;  2QMS A;  2Y3A B;  1QG1 E;  1H9O A;  1QAD A;  1F1W A;  1OO3 A;  1X27 A;  3BUM B;  3TKZ A;  4OHI A;  3US4 A;  1AOT F;  3M7F A;  4OHH A;  1O41 A;  1O4N A;  3GXX A;  2C9W A;  5AUL A;  2MK2 A;  5EG3 B;  2K79 B;  1O4Q A;  1D4W A;  1TCE A;  2H8H A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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