4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 7
molecule tags Signaling protein
source organism Homo sapiens
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
2K79B 1O4LA 1RJAA 1JYUA 1M27A 1BHFA 1O4DA 3HHMB 1JU5A 4NWFA 4JE4A 1F1WA 3QWYA 3VRPA 3CXLA 3M7FA 3N8MA 1A1AA 1O4AA 1KSWA 2XP1A 4OHIA 1O4OA 1O4BA 2FCIA 1B47A 1BHHA 1SHBA 2RSYA 1O4GA 1BFJA 1LUMA 5EG3B 3S8LA 2LQWA 1A1BA 3C7IA 1TZEE 2CR4A 4OHEA 4OHDA 2DLYA 4U17A 2CRHA 1BMBA 4X6SA 1IS0A 1QG1E 1Y57A 3OV1A 3VRRA 1O4QA 1I3ZA 1H9OA 1MILA 1SHAA 3BKBA 4GPLB 2LQNA 4F59A 2EKXA 4FL3A 3VS7A 4QSYA 3TL0A 1O42A 3OB2B 2EO3A 5DF6A 3CWGA 2CBLA 3CBLA 4OHLA 2CIAA 1ZFPE 3NHNA 2EL8A 2CI9A 1IJRA 2Y1NA 2AUGA 2HDXA 2PLEA 1BKLA 4ROJA 2PLDA 2DCRA 4NWGA 4U1PA 1AOTF 3WA4A 2MRKA 3VS3A 1R1PA 2DX0A 3VGOA 1LCJA 2EYZA 1GRIA 2IUGA 3PJPA 1X27A 3N7YA 1A09A 1D4TA 3S9KA 1F2FA 3GQIB 3PS5A 4F5BA 3BUXB 1BLKA 1A81A 1AYBA 1G83A 2MQIA 1O4NA 3US4A 5DC0B 1R1SA 2B3OA 2C0TA 1YVLA 4E68A 4P9ZA 3EAZA 2IUIA 1SHDA 3MXCA 5AXIA 1BF5A 1AYDA 2RMXA 3OP0A 1O4CA 2HUWA 2JYQA 4K44A 1KA6A 1FBVA 3PFVA 4E93A 1RQQC 1WQUA 4JGHA 3UF4A 2AOAA 1BLJA 1FYRA 3MXYA 5HKZA 1D1ZA 3GXWA 1O4PA 3N84A 4A4CA 1RPYA 3IMDA 1O48A 1BM2A 4A4BA 1A1CA 1OPLA 5GJHA 4OHHA 1MW4A 1FHSA 3VS6A 1OO4A 1Z3KA 1NRVA 1O43A 3GXXA 2MC1A 2OQ1A 1R1QA 5EELA 2GE9A 3PSKA 2ETZA 4XZ0A 3TKZA 1K9AA 1CSZA 2GSBA 3HCKA 1FU6A 2OZOA 3VRZA 2LCTA 4FBNA 3VS2A 2K7AB 1AD5A 5IBMA 1AYCA 1LUNA 4DGPA 4WWQA 3BUOB 2IUHA 2RVFA 1SPSA 5J3XA 1UUSA 2EO6A 2L4KA 3S8OA 3PLFB 1P13A 1O4MA 1UURA 4F5AA 4LUDA 5GJIA 4H34A 2BBUA 1CWEA 3VS4A 5AULA 2YU7A 3OB1B 1BHHB 2KNOA 2EYYA 1O47A 1X6CA 1SKJA 1X0NA 1O45A 1XA6A 5DC9A 3HIZB 4GL9E 2RORA 1A07A 1JWOA 2IZVA 3ZNIA 1O4EA 3CD3A 3VRQA 3VS0A 1O46A 3OVEA 2DLZA 4JEGA 5KAZA 3PQZA 2SHPA 2Y3AB 2SRCA 2C9WA 3VRYA 4EIHA 2LNWA 2H8HA 1PICA 1A1EA 1QADA 1LUKA 1AYAA 1KC2A 2H5KA 4GWFA 3BUWB 4P9VA 2QMSA 1D4WA 1BFIA 1O44A 4DGXA 1LCKA 3UYOA 3VRNA 1CWDL 1OO3A 5DC4A 1O41A 5I6VA 2ABLA 1NZLA 1Y1UA 1O4KA 1O4RA 1QCFA 3IMJA 5EHRA 5IBSA 1A08A 1BG1A 4TZIA 2Y1MA 2L6KA 5EEQA 2DVJA 2HDVA 1O4JA 4XZ1A 3QWXX 1JYQA 2EU0A 1FBZA 1LKLA 3PSJA 1CSYA 1KA7A 1BKMA 1YVHA 4L1BB 2HMHA 3MAZA 1M61A 2CI8A 2DM0A 2C0IA 2AOBA 1LKKA 1AOUF 1CJ1A 3T04A 2MRJA 1O4HA 3IN8A 4K2RA 4M4ZA 1LUIA 1O4FA 2H46E 3EACA 4LUEA 1HCTB 2VIFA 3BUMB 1GHUA 2PNBA 2YSXA 5HKYA 3VS1A 1NZVA 1O49A 2EOBA 5BO4A 3K2MA 3IN7A 4FL2A 2CS0A 2L3TA 1FMKA 5CDWA 2EYVA 1SPRA 1FU5A 4K45A 5D0JA 3KFJA 2C0OA 4D8KA 2MK2A 4K11A 2PNAA 2HCKA 5HKWA 5EHPA 1HCSB 1JYRA 1TCEA 3S8NA 4EY0A 2PTKA 4H1OA 2LNXA 1AB2A 1OPKA 3VROA 2ECDA 3VS5A 2FO0A 3BUNB 2KK6A 1O4IA
chains in the Genus database with same CATH superfamily
2K79B 1O4LA 1RJAA 1JYUA 1M27A 1BHFA 1O4DA 3HHMB 1JU5A 4NWFA 4JE4A 1F1WA 3QWYA 3VRPA 3CXLA 3M7FA 3N8MA 1A1AA 1O4AA 1KSWA 2XP1A 4OHIA 1O4OA 1O4BA 2FCIA 1B47A 1BHHA 1SHBA 2RSYA 1O4GA 1BFJA 1LUMA 5EG3B 3S8LA 2LQWA 1A1BA 3C7IA 1TZEE 2CR4A 4OHEA 4OHDA 2KGYA 2DLYA 4U17A 2CRHA 1BMBA 4X6SA 1IS0A 1QG1E 1Y57A 3OV1A 3VRRA 1O4QA 1I3ZA 1H9OA 1MILA 1SHAA 3BKBA 4GPLB 2LQNA 4F59A 2EKXA 4FL3A 3VS7A 4QSYA 3TL0A 1O42A 3OB2B 2EO3A 5DF6A 3CWGA 2CBLA 3CBLA 4OHLA 2CIAA 1ZFPE 3NHNA 2EL8A 2CI9A 1IJRA 2Y1NA 2AUGA 2HDXA 2PLEA 1BKLA 4ROJA 2PLDA 2DCRA 4NWGA 4U1PA 1AOTF 3WA4A 2MRKA 3VS3A 1R1PA 2DX0A 3VGOA 1LCJA 2EYZA 1GRIA 2IUGA 3PJPA 1X27A 3N7YA 1A09A 1D4TA 3S9KA 1F2FA 3GQIB 3PS5A 4F5BA 3BUXB 1BLKA 1A81A 1AYBA 1G83A 2MQIA 1O4NA 3US4A 5DC0B 1R1SA 2B3OA 2C0TA 1YVLA 4E68A 4P9ZA 3EAZA 2IUIA 1SHDA 3MXCA 3K2TA 5AXIA 1BF5A 1AYDA 2RMXA 3OP0A 1O4CA 2HUWA 2JYQA 4K44A 1KA6A 1FBVA 3PFVA 4E93A 1RQQC 1WQUA 4JGHA 3UF4A 2AOAA 1BLJA 1FYRA 3MXYA 5HKZA 1D1ZA 3GXWA 1O4PA 3N84A 4A4CA 1RPYA 3IMDA 1O48A 1BM2A 4A4BA 1A1CA 1OPLA 5GJHA 4OHHA 1MW4A 1FHSA 3VS6A 1OO4A 1Z3KA 1NRVA 1O43A 3GXXA 2MC1A 2OQ1A 1R1QA 5EELA 2GE9A 3PSKA 2ETZA 4XZ0A 3TKZA 1K9AA 1CSZA 2GSBA 3HCKA 1FU6A 2OZOA 3VRZA 2LCTA 4FBNA 3VS2A 2K7AB 1AD5A 5IBMA 1AYCA 1LUNA 4DGPA 4WWQA 3BUOB 2IUHA 2LRAA 2RVFA 1SPSA 5J3XA 1UUSA 2EO6A 2L4KA 3S8OA 3PLFB 1P13A 1O4MA 1UURA 4F5AA 4LUDA 5GJIA 4H34A 2BBUA 1CWEA 3VS4A 5AULA 2YU7A 3OB1B 1BHHB 2KNOA 2EYYA 1O47A 1X6CA 1SKJA 1X0NA 1O45A 1XA6A 5DC9A 3HIZB 4GL9E 2RORA 1A07A 1JWOA 2IZVA 3ZNIA 1O4EA 3CD3A 3VRQA 3VS0A 1O46A 3OVEA 2DLZA 4JEGA 5KAZA 3PQZA 2SHPA 2Y3AB 2SRCA 2C9WA 3VRYA 4EIHA 2LNWA 2H8HA 1PICA 1A1EA 1QADA 1LUKA 3LYVA 1AYAA 1KC2A 2H5KA 4GWFA 3BUWB 4P9VA 2QMSA 1D4WA 1BFIA 1O44A 4DGXA 1LCKA 3UYOA 3VRNA 1CWDL 1OO3A 5DC4A 1O41A 5I6VA 2ABLA 1NZLA 1Y1UA 1O4KA 1O4RA 1QCFA 3IMJA 5EHRA 5IBSA 1A08A 1BG1A 4TZIA 2Y1MA 2L6KA 5EEQA 2DVJA 2HDVA 1O4JA 4XZ1A 3QWXX 1JYQA 2EU0A 1FBZA 1LKLA 3PSJA 1CSYA 1KA7A 1BKMA 1YVHA 4L1BB 2HMHA 3MAZA 1M61A 2CI8A 2DM0A 2C0IA 2AOBA 1LKKA 1AOUF 1CJ1A 3T04A 2MRJA 1O4HA 3IN8A 4K2RA 4M4ZA 1LUIA 1O4FA 2H46E 3EACA 4LUEA 1HCTB 2VIFA 3BUMB 1GHUA 2PNBA 2YSXA 5HKYA 3VS1A 1NZVA 1O49A 2EOBA 5BO4A 3K2MA 3IN7A 4FL2A 2CS0A 2L3TA 1FMKA 5CDWA 2EYVA 1SPRA 1FU5A 4K45A 5D0JA 3KFJA 2C0OA 4D8KA 2MK2A 4K11A 2PNAA 2HCKA 5HKWA 5EHPA 1HCSB 1JYRA 1TCEA 3S8NA 4EY0A 2PTKA 4H1OA 2LNXA 1AB2A 1OPKA 3VROA 2ECDA 3VS5A 2FO0A 3BUNB 2KK6A 1O4IA
chains in the Genus database with same CATH topology
2K79B 1O4LA 1RJAA 1JYUA 1M27A 1BHFA 1O4DA 3HHMB 1JU5A 4NWFA 4JE4A 1F1WA 3QWYA 3VRPA 3CXLA 3M7FA 3N8MA 1A1AA 1O4AA 1KSWA 2XP1A 4OHIA 1O4OA 1O4BA 2FCIA 1B47A 1BHHA 1SHBA 2RSYA 1O4GA 1BFJA 1LUMA 5EG3B 3S8LA 2LQWA 1A1BA 3C7IA 1TZEE 2CR4A 4OHEA 4OHDA 2DLYA 4U17A 2CRHA 1BMBA 4X6SA 1IS0A 1QG1E 1Y57A 3OV1A 3VRRA 1O4QA 1I3ZA 1H9OA 1MILA 1SHAA 3BKBA 4GPLB 2LQNA 4F59A 2EKXA 4FL3A 3VS7A 4QSYA 3TL0A 1O42A 3OB2B 2EO3A 5DF6A 3CWGA 2CBLA 3CBLA 4OHLA 2CIAA 1ZFPE 3NHNA 2EL8A 2CI9A 1IJRA 2Y1NA 2AUGA 2HDXA 2PLEA 1BKLA 4ROJA 2PLDA 2DCRA 4NWGA 4U1PA 1AOTF 3WA4A 2MRKA 3VS3A 1R1PA 2DX0A 3VGOA 1LCJA 2EYZA 1GRIA 2IUGA 3PJPA 1X27A 3N7YA 1A09A 1D4TA 3S9KA 1F2FA 3GQIB 3PS5A 4F5BA 3BUXB 1BLKA 1A81A 1AYBA 1G83A 2MQIA 1O4NA 3US4A 5DC0B 1R1SA 2B3OA 2C0TA 1YVLA 4E68A 4P9ZA 3EAZA 2IUIA 1SHDA 3MXCA 5AXIA 1BF5A 1AYDA 2RMXA 3OP0A 1O4CA 2HUWA 2JYQA 4K44A 1KA6A 1FBVA 3PFVA 4E93A 1RQQC 1WQUA 4JGHA 3UF4A 2AOAA 1BLJA 1FYRA 3MXYA 5HKZA 1D1ZA 3GXWA 1O4PA 3N84A 4A4CA 1RPYA 3IMDA 1O48A 1BM2A 4A4BA 1A1CA 1OPLA 5GJHA 4OHHA 1MW4A 1FHSA 3VS6A 1OO4A 1Z3KA 1NRVA 1O43A 3GXXA 2MC1A 2OQ1A 1R1QA 5EELA 2GE9A 3PSKA 2ETZA 4XZ0A 3TKZA 1K9AA 1CSZA 2GSBA 3HCKA 1FU6A 2OZOA 3VRZA 2LCTA 4FBNA 3VS2A 2K7AB 1AD5A 5IBMA 1AYCA 1LUNA 4DGPA 4WWQA 3BUOB 2IUHA 2RVFA 1SPSA 5J3XA 1UUSA 2EO6A 2L4KA 3S8OA 3PLFB 1P13A 1O4MA 1UURA 4F5AA 4LUDA 5GJIA 4H34A 2BBUA 1CWEA 3VS4A 5AULA 2YU7A 3OB1B 1BHHB 2KNOA 2EYYA 1O47A 1X6CA 1SKJA 1X0NA 1O45A 1XA6A 5DC9A 3HIZB 4GL9E 2RORA 1A07A 1JWOA 2IZVA 3ZNIA 1O4EA 3CD3A 3VRQA 3VS0A 1O46A 3OVEA 2DLZA 4JEGA 5KAZA 3PQZA 2SHPA 2Y3AB 2SRCA 2C9WA 3VRYA 4EIHA 2LNWA 2H8HA 1PICA 1A1EA 1QADA 1LUKA 1AYAA 1KC2A 2H5KA 4GWFA 3BUWB 4P9VA 2QMSA 1D4WA 1BFIA 1O44A 4DGXA 1LCKA 3UYOA 3VRNA 1CWDL 1OO3A 5DC4A 1O41A 5I6VA 2ABLA 1NZLA 1Y1UA 1O4KA 1O4RA 1QCFA 3IMJA 5EHRA 5IBSA 1A08A 1BG1A 4TZIA 2Y1MA 2L6KA 5EEQA 2DVJA 2HDVA 1O4JA 4XZ1A 3QWXX 1JYQA 2EU0A 1FBZA 1LKLA 3PSJA 1CSYA 1KA7A 1BKMA 1YVHA 4L1BB 2HMHA 3MAZA 1M61A 2CI8A 2DM0A 2C0IA 2AOBA 1LKKA 1AOUF 1CJ1A 3T04A 2MRJA 1O4HA 3IN8A 4K2RA 4M4ZA 1LUIA 1O4FA 2H46E 3EACA 4LUEA 1HCTB 2VIFA 3BUMB 1GHUA 2PNBA 2YSXA 5HKYA 3VS1A 1NZVA 1O49A 2EOBA 5BO4A 3K2MA 3IN7A 4FL2A 2CS0A 2L3TA 1FMKA 5CDWA 2EYVA 1SPRA 1FU5A 4K45A 5D0JA 3KFJA 2C0OA 4D8KA 2MK2A 4K11A 2PNAA 2HCKA 5HKWA 5EHPA 1HCSB 1JYRA 1TCEA 3S8NA 4EY0A 2PTKA 4H1OA 2LNXA 1AB2A 1OPKA 3VROA 2ECDA 3VS5A 2FO0A 3BUNB 2KK6A 1O4IA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2K79 B;  1O4L A;  1RJA A;  1JYU A;  1M27 A;  1BHF A;  1O4D A;  3HHM B;  1JU5 A;  4NWF A;  4JE4 A;  1F1W A;  3QWY A;  3VRP A;  3CXL A;  3M7F A;  3N8M A;  1A1A A;  1O4A A;  1KSW A;  2XP1 A;  4OHI A;  1O4O A;  1O4B A;  2FCI A;  1B47 A;  1BHH A;  1SHB A;  2RSY A;  1O4G A;  1BFJ A;  1LUM A;  5EG3 B;  3S8L A;  2LQW A;  1A1B A;  3C7I A;  1TZE E;  2CR4 A;  4OHE A;  4OHD A;  2DLY A;  4U17 A;  2CRH A;  1BMB A;  4X6S A;  1IS0 A;  1QG1 E;  1Y57 A;  3OV1 A;  3VRR A;  1O4Q A;  1I3Z A;  1H9O A;  1MIL A;  1SHA A;  3BKB A;  4GPL B;  2LQN A;  4F59 A;  2EKX A;  4FL3 A;  3VS7 A;  4QSY A;  3TL0 A;  1O42 A;  3OB2 B;  2EO3 A;  5DF6 A;  3CWG A;  2CBL A;  3CBL A;  4OHL A;  2CIA A;  1ZFP E;  3NHN A;  2EL8 A;  2CI9 A;  1IJR A;  2Y1N A;  2AUG A;  2HDX A;  2PLE A;  1BKL A;  4ROJ A;  2PLD A;  2DCR A;  4NWG A;  4U1P A;  1AOT F;  3WA4 A;  2MRK A;  3VS3 A;  1R1P A;  2DX0 A;  3VGO A;  1LCJ A;  2EYZ A;  1GRI A;  2IUG A;  3PJP A;  1X27 A;  3N7Y A;  1A09 A;  1D4T A;  3S9K A;  1F2F A;  3GQI B;  3PS5 A;  4F5B A;  3BUX B;  1BLK A;  1A81 A;  1AYB A;  1G83 A;  2MQI A;  1O4N A;  3US4 A;  5DC0 B;  1R1S A;  2B3O A;  2C0T A;  1YVL A;  4E68 A;  4P9Z A;  3EAZ A;  2IUI A;  1SHD A;  3MXC A;  5AXI A;  1BF5 A;  1AYD A;  2RMX A;  3OP0 A;  1O4C A;  2HUW A;  2JYQ A;  4K44 A;  1KA6 A;  1FBV A;  3PFV A;  4E93 A;  1RQQ C;  1WQU A;  4JGH A;  3UF4 A;  2AOA A;  1BLJ A;  1FYR A;  3MXY A;  5HKZ A;  1D1Z A;  3GXW A;  1O4P A;  3N84 A;  4A4C A;  1RPY A;  3IMD A;  1O48 A;  1BM2 A;  4A4B A;  1A1C A;  1OPL A;  5GJH A;  4OHH A;  1MW4 A;  1FHS A;  3VS6 A;  1OO4 A;  1Z3K A;  1NRV A;  1O43 A;  3GXX A;  2MC1 A;  2OQ1 A;  1R1Q A;  5EEL A;  2GE9 A;  3PSK A;  2ETZ A;  4XZ0 A;  3TKZ A;  1K9A A;  1CSZ A;  2GSB A;  3HCK A;  1FU6 A;  2OZO A;  3VRZ A;  2LCT A;  4FBN A;  3VS2 A;  2K7A B;  1AD5 A;  5IBM A;  1AYC A;  1LUN A;  4DGP A;  4WWQ A;  3BUO B;  2IUH A;  2RVF A;  1SPS A;  5J3X A;  1UUS A;  2EO6 A;  2L4K A;  3S8O A;  3PLF B;  1P13 A;  1O4M A;  1UUR A;  4F5A A;  4LUD A;  5GJI A;  4H34 A;  2BBU A;  1CWE A;  3VS4 A;  5AUL A;  2YU7 A;  3OB1 B;  1BHH B;  2KNO A;  2EYY A;  1O47 A;  1X6C A;  1SKJ A;  1X0N A;  1O45 A;  1XA6 A;  5DC9 A;  3HIZ B;  4GL9 E;  2ROR A;  1A07 A;  1JWO A;  2IZV A;  3ZNI A;  1O4E A;  3CD3 A;  3VRQ A;  3VS0 A;  1O46 A;  3OVE A;  2DLZ A;  4JEG A;  5KAZ A;  3PQZ A;  2SHP A;  2Y3A B;  2SRC A;  2C9W A;  3VRY A;  4EIH A;  2LNW A;  2H8H A;  1PIC A;  1A1E A;  1QAD A;  1LUK A;  1AYA A;  1KC2 A;  2H5K A;  4GWF A;  3BUW B;  4P9V A;  2QMS A;  1D4W A;  1BFI A;  1O44 A;  4DGX A;  1LCK A;  3UYO A;  3VRN A;  1CWD L;  1OO3 A;  5DC4 A;  1O41 A;  5I6V A;  2ABL A;  1NZL A;  1Y1U A;  1O4K A;  1O4R A;  1QCF A;  3IMJ A;  5EHR A;  5IBS A;  1A08 A;  1BG1 A;  4TZI A;  2Y1M A;  2L6K A;  5EEQ A;  2DVJ A;  2HDV A;  1O4J A;  4XZ1 A;  3QWX X;  1JYQ A;  2EU0 A;  1FBZ A;  1LKL A;  3PSJ A;  1CSY A;  1KA7 A;  1BKM A;  1YVH A;  4L1B B;  2HMH A;  3MAZ A;  1M61 A;  2CI8 A;  2DM0 A;  2C0I A;  2AOB A;  1LKK A;  1AOU F;  1CJ1 A;  3T04 A;  2MRJ A;  1O4H A;  3IN8 A;  4K2R A;  4M4Z A;  1LUI A;  1O4F A;  2H46 E;  3EAC A;  4LUE A;  1HCT B;  2VIF A;  3BUM B;  1GHU A;  2PNB A;  2YSX A;  5HKY A;  3VS1 A;  1NZV A;  1O49 A;  2EOB A;  5BO4 A;  3K2M A;  3IN7 A;  4FL2 A;  2CS0 A;  2L3T A;  1FMK A;  5CDW A;  2EYV A;  1SPR A;  1FU5 A;  4K45 A;  5D0J A;  3KFJ A;  2C0O A;  4D8K A;  2MK2 A;  4K11 A;  2PNA A;  2HCK A;  5HKW A;  5EHP A;  1HCS B;  1JYR A;  1TCE A;  3S8N A;  4EY0 A;  2PTK A;  4H1O A;  2LNX A;  1AB2 A;  1OPK A;  3VRO A;  2ECD A;  3VS5 A;  2FO0 A;  3BUN B;  2KK6 A;  1O4I A; 
#chains in the Genus database with same CATH topology
 2K79 B;  1O4L A;  1RJA A;  1JYU A;  1M27 A;  1BHF A;  1O4D A;  3HHM B;  1JU5 A;  4NWF A;  4JE4 A;  1F1W A;  3QWY A;  3VRP A;  3CXL A;  3M7F A;  3N8M A;  1A1A A;  1O4A A;  1KSW A;  2XP1 A;  4OHI A;  1O4O A;  1O4B A;  2FCI A;  1B47 A;  1BHH A;  1SHB A;  2RSY A;  1O4G A;  1BFJ A;  1LUM A;  5EG3 B;  3S8L A;  2LQW A;  1A1B A;  3C7I A;  1TZE E;  2CR4 A;  4OHE A;  4OHD A;  2KGY A;  2DLY A;  4U17 A;  2CRH A;  1BMB A;  4X6S A;  1IS0 A;  1QG1 E;  1Y57 A;  3OV1 A;  3VRR A;  1O4Q A;  1I3Z A;  1H9O A;  1MIL A;  1SHA A;  3BKB A;  4GPL B;  2LQN A;  4F59 A;  2EKX A;  4FL3 A;  3VS7 A;  4QSY A;  3TL0 A;  1O42 A;  3OB2 B;  2EO3 A;  5DF6 A;  3CWG A;  2CBL A;  3CBL A;  4OHL A;  2CIA A;  1ZFP E;  3NHN A;  2EL8 A;  2CI9 A;  1IJR A;  2Y1N A;  2AUG A;  2HDX A;  2PLE A;  1BKL A;  4ROJ A;  2PLD A;  2DCR A;  4NWG A;  4U1P A;  1AOT F;  3WA4 A;  2MRK A;  3VS3 A;  1R1P A;  2DX0 A;  3VGO A;  1LCJ A;  2EYZ A;  1GRI A;  2IUG A;  3PJP A;  1X27 A;  3N7Y A;  1A09 A;  1D4T A;  3S9K A;  1F2F A;  3GQI B;  3PS5 A;  4F5B A;  3BUX B;  1BLK A;  1A81 A;  1AYB A;  1G83 A;  2MQI A;  1O4N A;  3US4 A;  5DC0 B;  1R1S A;  2B3O A;  2C0T A;  1YVL A;  4E68 A;  4P9Z A;  3EAZ A;  2IUI A;  1SHD A;  3MXC A;  3K2T A;  5AXI A;  1BF5 A;  1AYD A;  2RMX A;  3OP0 A;  1O4C A;  2HUW A;  2JYQ A;  4K44 A;  1KA6 A;  1FBV A;  3PFV A;  4E93 A;  1RQQ C;  1WQU A;  4JGH A;  3UF4 A;  2AOA A;  1BLJ A;  1FYR A;  3MXY A;  5HKZ A;  1D1Z A;  3GXW A;  1O4P A;  3N84 A;  4A4C A;  1RPY A;  3IMD A;  1O48 A;  1BM2 A;  4A4B A;  1A1C A;  1OPL A;  5GJH A;  4OHH A;  1MW4 A;  1FHS A;  3VS6 A;  1OO4 A;  1Z3K A;  1NRV A;  1O43 A;  3GXX A;  2MC1 A;  2OQ1 A;  1R1Q A;  5EEL A;  2GE9 A;  3PSK A;  2ETZ A;  4XZ0 A;  3TKZ A;  1K9A A;  1CSZ A;  2GSB A;  3HCK A;  1FU6 A;  2OZO A;  3VRZ A;  2LCT A;  4FBN A;  3VS2 A;  2K7A B;  1AD5 A;  5IBM A;  1AYC A;  1LUN A;  4DGP A;  4WWQ A;  3BUO B;  2IUH A;  2LRA A;  2RVF A;  1SPS A;  5J3X A;  1UUS A;  2EO6 A;  2L4K A;  3S8O A;  3PLF B;  1P13 A;  1O4M A;  1UUR A;  4F5A A;  4LUD A;  5GJI A;  4H34 A;  2BBU A;  1CWE A;  3VS4 A;  5AUL A;  2YU7 A;  3OB1 B;  1BHH B;  2KNO A;  2EYY A;  1O47 A;  1X6C A;  1SKJ A;  1X0N A;  1O45 A;  1XA6 A;  5DC9 A;  3HIZ B;  4GL9 E;  2ROR A;  1A07 A;  1JWO A;  2IZV A;  3ZNI A;  1O4E A;  3CD3 A;  3VRQ A;  3VS0 A;  1O46 A;  3OVE A;  2DLZ A;  4JEG A;  5KAZ A;  3PQZ A;  2SHP A;  2Y3A B;  2SRC A;  2C9W A;  3VRY A;  4EIH A;  2LNW A;  2H8H A;  1PIC A;  1A1E A;  1QAD A;  1LUK A;  3LYV A;  1AYA A;  1KC2 A;  2H5K A;  4GWF A;  3BUW B;  4P9V A;  2QMS A;  1D4W A;  1BFI A;  1O44 A;  4DGX A;  1LCK A;  3UYO A;  3VRN A;  1CWD L;  1OO3 A;  5DC4 A;  1O41 A;  5I6V A;  2ABL A;  1NZL A;  1Y1U A;  1O4K A;  1O4R A;  1QCF A;  3IMJ A;  5EHR A;  5IBS A;  1A08 A;  1BG1 A;  4TZI A;  2Y1M A;  2L6K A;  5EEQ A;  2DVJ A;  2HDV A;  1O4J A;  4XZ1 A;  3QWX X;  1JYQ A;  2EU0 A;  1FBZ A;  1LKL A;  3PSJ A;  1CSY A;  1KA7 A;  1BKM A;  1YVH A;  4L1B B;  2HMH A;  3MAZ A;  1M61 A;  2CI8 A;  2DM0 A;  2C0I A;  2AOB A;  1LKK A;  1AOU F;  1CJ1 A;  3T04 A;  2MRJ A;  1O4H A;  3IN8 A;  4K2R A;  4M4Z A;  1LUI A;  1O4F A;  2H46 E;  3EAC A;  4LUE A;  1HCT B;  2VIF A;  3BUM B;  1GHU A;  2PNB A;  2YSX A;  5HKY A;  3VS1 A;  1NZV A;  1O49 A;  2EOB A;  5BO4 A;  3K2M A;  3IN7 A;  4FL2 A;  2CS0 A;  2L3T A;  1FMK A;  5CDW A;  2EYV A;  1SPR A;  1FU5 A;  4K45 A;  5D0J A;  3KFJ A;  2C0O A;  4D8K A;  2MK2 A;  4K11 A;  2PNA A;  2HCK A;  5HKW A;  5EHP A;  1HCS B;  1JYR A;  1TCE A;  3S8N A;  4EY0 A;  2PTK A;  4H1O A;  2LNX A;  1AB2 A;  1OPK A;  3VRO A;  2ECD A;  3VS5 A;  2FO0 A;  3BUN B;  2KK6 A;  1O4I A; 
#chains in the Genus database with same CATH homology
 2K79 B;  1O4L A;  1RJA A;  1JYU A;  1M27 A;  1BHF A;  1O4D A;  3HHM B;  1JU5 A;  4NWF A;  4JE4 A;  1F1W A;  3QWY A;  3VRP A;  3CXL A;  3M7F A;  3N8M A;  1A1A A;  1O4A A;  1KSW A;  2XP1 A;  4OHI A;  1O4O A;  1O4B A;  2FCI A;  1B47 A;  1BHH A;  1SHB A;  2RSY A;  1O4G A;  1BFJ A;  1LUM A;  5EG3 B;  3S8L A;  2LQW A;  1A1B A;  3C7I A;  1TZE E;  2CR4 A;  4OHE A;  4OHD A;  2DLY A;  4U17 A;  2CRH A;  1BMB A;  4X6S A;  1IS0 A;  1QG1 E;  1Y57 A;  3OV1 A;  3VRR A;  1O4Q A;  1I3Z A;  1H9O A;  1MIL A;  1SHA A;  3BKB A;  4GPL B;  2LQN A;  4F59 A;  2EKX A;  4FL3 A;  3VS7 A;  4QSY A;  3TL0 A;  1O42 A;  3OB2 B;  2EO3 A;  5DF6 A;  3CWG A;  2CBL A;  3CBL A;  4OHL A;  2CIA A;  1ZFP E;  3NHN A;  2EL8 A;  2CI9 A;  1IJR A;  2Y1N A;  2AUG A;  2HDX A;  2PLE A;  1BKL A;  4ROJ A;  2PLD A;  2DCR A;  4NWG A;  4U1P A;  1AOT F;  3WA4 A;  2MRK A;  3VS3 A;  1R1P A;  2DX0 A;  3VGO A;  1LCJ A;  2EYZ A;  1GRI A;  2IUG A;  3PJP A;  1X27 A;  3N7Y A;  1A09 A;  1D4T A;  3S9K A;  1F2F A;  3GQI B;  3PS5 A;  4F5B A;  3BUX B;  1BLK A;  1A81 A;  1AYB A;  1G83 A;  2MQI A;  1O4N A;  3US4 A;  5DC0 B;  1R1S A;  2B3O A;  2C0T A;  1YVL A;  4E68 A;  4P9Z A;  3EAZ A;  2IUI A;  1SHD A;  3MXC A;  5AXI A;  1BF5 A;  1AYD A;  2RMX A;  3OP0 A;  1O4C A;  2HUW A;  2JYQ A;  4K44 A;  1KA6 A;  1FBV A;  3PFV A;  4E93 A;  1RQQ C;  1WQU A;  4JGH A;  3UF4 A;  2AOA A;  1BLJ A;  1FYR A;  3MXY A;  5HKZ A;  1D1Z A;  3GXW A;  1O4P A;  3N84 A;  4A4C A;  1RPY A;  3IMD A;  1O48 A;  1BM2 A;  4A4B A;  1A1C A;  1OPL A;  5GJH A;  4OHH A;  1MW4 A;  1FHS A;  3VS6 A;  1OO4 A;  1Z3K A;  1NRV A;  1O43 A;  3GXX A;  2MC1 A;  2OQ1 A;  1R1Q A;  5EEL A;  2GE9 A;  3PSK A;  2ETZ A;  4XZ0 A;  3TKZ A;  1K9A A;  1CSZ A;  2GSB A;  3HCK A;  1FU6 A;  2OZO A;  3VRZ A;  2LCT A;  4FBN A;  3VS2 A;  2K7A B;  1AD5 A;  5IBM A;  1AYC A;  1LUN A;  4DGP A;  4WWQ A;  3BUO B;  2IUH A;  2RVF A;  1SPS A;  5J3X A;  1UUS A;  2EO6 A;  2L4K A;  3S8O A;  3PLF B;  1P13 A;  1O4M A;  1UUR A;  4F5A A;  4LUD A;  5GJI A;  4H34 A;  2BBU A;  1CWE A;  3VS4 A;  5AUL A;  2YU7 A;  3OB1 B;  1BHH B;  2KNO A;  2EYY A;  1O47 A;  1X6C A;  1SKJ A;  1X0N A;  1O45 A;  1XA6 A;  5DC9 A;  3HIZ B;  4GL9 E;  2ROR A;  1A07 A;  1JWO A;  2IZV A;  3ZNI A;  1O4E A;  3CD3 A;  3VRQ A;  3VS0 A;  1O46 A;  3OVE A;  2DLZ A;  4JEG A;  5KAZ A;  3PQZ A;  2SHP A;  2Y3A B;  2SRC A;  2C9W A;  3VRY A;  4EIH A;  2LNW A;  2H8H A;  1PIC A;  1A1E A;  1QAD A;  1LUK A;  1AYA A;  1KC2 A;  2H5K A;  4GWF A;  3BUW B;  4P9V A;  2QMS A;  1D4W A;  1BFI A;  1O44 A;  4DGX A;  1LCK A;  3UYO A;  3VRN A;  1CWD L;  1OO3 A;  5DC4 A;  1O41 A;  5I6V A;  2ABL A;  1NZL A;  1Y1U A;  1O4K A;  1O4R A;  1QCF A;  3IMJ A;  5EHR A;  5IBS A;  1A08 A;  1BG1 A;  4TZI A;  2Y1M A;  2L6K A;  5EEQ A;  2DVJ A;  2HDV A;  1O4J A;  4XZ1 A;  3QWX X;  1JYQ A;  2EU0 A;  1FBZ A;  1LKL A;  3PSJ A;  1CSY A;  1KA7 A;  1BKM A;  1YVH A;  4L1B B;  2HMH A;  3MAZ A;  1M61 A;  2CI8 A;  2DM0 A;  2C0I A;  2AOB A;  1LKK A;  1AOU F;  1CJ1 A;  3T04 A;  2MRJ A;  1O4H A;  3IN8 A;  4K2R A;  4M4Z A;  1LUI A;  1O4F A;  2H46 E;  3EAC A;  4LUE A;  1HCT B;  2VIF A;  3BUM B;  1GHU A;  2PNB A;  2YSX A;  5HKY A;  3VS1 A;  1NZV A;  1O49 A;  2EOB A;  5BO4 A;  3K2M A;  3IN7 A;  4FL2 A;  2CS0 A;  2L3T A;  1FMK A;  5CDW A;  2EYV A;  1SPR A;  1FU5 A;  4K45 A;  5D0J A;  3KFJ A;  2C0O A;  4D8K A;  2MK2 A;  4K11 A;  2PNA A;  2HCK A;  5HKW A;  5EHP A;  1HCS B;  1JYR A;  1TCE A;  3S8N A;  4EY0 A;  2PTK A;  4H1O A;  2LNX A;  1AB2 A;  1OPK A;  3VRO A;  2ECD A;  3VS5 A;  2FO0 A;  3BUN B;  2KK6 A;  1O4I A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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