4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 7
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
3IMJA 2OQ1A 4FL2A 1A09A 4E93A 4LUDA 3M7FA 2Y1NA 2MK2A 2K79B 1BLKA 1O4GA 1D1ZA 1FYRA 5EG3B 3GXWA 1O4AA 1ZFPE 4WWQA 4K11A 1FMKA 3OB2B 1O4HA 3PSKA 1JYQA 3N8MA 2HMHA 2PLEA 1O4QA 1LUMA 1AYCA 1HCTB 3CWGA 1RJAA 4JEGA 2Y3AB 3VS7A 3N7YA 3VS6A 2H5KA 2ABLA 2GSBA 5J3XA 2CI9A 2H46E 2IUIA 1JYRA 1GRIA 1IJRA 2EO3A 1A81A 2DLYA 1M61A 5DF6A 1GHUA 1O4LA 3US4A 1A07A 4OHLA 5HKZA 2LNXA 4U1PA 3CXLA 3BKBA 1LUIA 2MQIA 1O4BA 2XP1A 3C7IA 2YU7A 2CRHA 3BUOB 2EYVA 1O4JA 5HKYA 1MILA 4JGHA 2RMXA 1KC2A 2L4KA 3IMDA 2HDVA 3ZNIA 2HCKA 1R1SA 1I3ZA 1XA6A 2HDXA 2MC1A 3VS4A 4GWFA 5D0JA 3VS1A 1O4NA 1Y57A 3VRNA 2DLZA 3TKZA 1O49A 2PNAA 1O4IA 2C0OA 1TCEA 4EY0A 1D4TA 1A1BA 2GE9A 3MXCA 5BO4A 3PQZA 3VS0A 2YSXA 1CWEA 1BF5A 4F59A 4NWGA 3S8OA 2ECDA 1O4OA 1A1CA 4A4CA 3VROA 3QWXX 1IS0A 1O4CA 4E68A 3PFVA 4QSYA 2BBUA 2RSYA 2C0IA 4TZIA 1H9OA 1JWOA 3CD3A 3VRPA 3TL0A 4M4ZA 1X27A 2FO0A 1O45A 1CSYA 4GPLB 1A1AA 5IBSA 3PSJA 2RORA 1F2FA 1WQUA 1FHSA 1PICA 1O43A 1AOUF 2PLDA 1AYDA 3VS3A 2EL8A 1K9AA 1QG1E 2EO6A 3CBLA 1SHDA 5CDWA 1BG1A 4FL3A 1JYUA 3BUMB 3MXYA 2EOBA 2IUGA 3HCKA 5DC9A 3VS5A 5GJIA 5EHRA 1O42A 2IUHA 1QADA 3UYOA 1BKLA 4OHDA 4OHIA 2KNOA 4L1BB 4H1OA 2FCIA 2DX0A 1LUKA 1Z3KA 1M27A 1QCFA 3VGOA 1LCKA 3OP0A 5AULA 1D4WA 1FBZA 3VS2A 1O48A 2DM0A 4F5AA 1BHHA 2DCRA 2AUGA 4OHHA 2CI8A 1KA6A 2PTKA 3VRYA 1B47A 3OB1B 1YVLA 5EELA 1O4FA 1O47A 2LCTA 4A4BA 3BUNB 3NHNA 3KFJA 3PS5A 1O46A 4OHEA 1CJ1A 1SPRA 1O4EA 1AD5A 4U17A 1BFIA 3QWYA 2EKXA 2MRJA 3GXXA 5I6VA 4DGXA 1AB2A 1AYBA 2QMSA 2C9WA 2L6KA 4K44A 1CWDL 3HHMB 1G83A 3PLFB 2B3OA 2SRCA 2AOBA 4LUEA 2PNBA 1BLJA 4H34A 5AXIA 2LQNA 5EEQA 3EACA 3IN8A 3WA4A 1O44A 4K45A 3VRZA 4F5BA 1NZVA 1P13A 2DVJA 1FU6A 1RPYA 2HUWA 1LUNA 1BM2A 4D8KA 2CR4A 3K2MA 4P9VA 2OZOA 3S9KA 1FU5A 3OV1A 1R1PA 2CS0A 3S8LA 3BUWB 1KA7A 4NWFA 5DC4A 1BKMA 2RVFA 5DC0B 2JYQA 3N84A 4K2RA 3IN7A 1AOTF 1LCJA 5KAZA 4EIHA 1BHFA 1RQQC 3MAZA 3GQIB 5HKWA 3VRQA 5IBMA 1UUSA 1O4DA 1SPSA 2LQWA 1SHBA 1HCSB 3OVEA 1UURA 1OPLA 1O4PA 4FBNA 1A1EA 2EYYA 1NZLA 1O4KA 2L3TA 1BHHB 1OO3A 1TZEE 2IZVA 1NRVA 2MRKA 1LKKA 1LKLA 1A08A 2KK6A 2SHPA 1SKJA 2K7AB 1F1WA 1X6CA 3PJPA 1O41A 1X0NA 4DGPA 1BFJA 2Y1MA 1O4RA 2CBLA 4XZ0A 2ETZA 2LNWA 1R1QA 3S8NA 1CSZA 1FBVA 1AYAA 1MW4A 2AOAA 1OPKA 5GJHA 4XZ1A 4ROJA 4GL9E 4P9ZA 1SHAA 2H8HA 1JU5A 2C0TA 1BMBA 2VIFA 4X6SA 3HIZB 5EHPA 1YVHA 3UF4A 2EYZA 1Y1UA 3EAZA 1OO4A 4JE4A 2EU0A 3T04A 1KSWA 1O4MA 2CIAA 3VRRA 3BUXB
chains in the Genus database with same CATH superfamily
3IMJA 2OQ1A 4FL2A 1A09A 4E93A 4LUDA 3M7FA 2Y1NA 2MK2A 2K79B 1BLKA 1O4GA 1D1ZA 1FYRA 5EG3B 3GXWA 1O4AA 1ZFPE 4WWQA 4K11A 1FMKA 3OB2B 1O4HA 3PSKA 1JYQA 3N8MA 2HMHA 2PLEA 1O4QA 1LUMA 1AYCA 1HCTB 3CWGA 1RJAA 4JEGA 2Y3AB 3VS7A 3N7YA 3VS6A 2H5KA 2ABLA 2GSBA 5J3XA 2CI9A 2H46E 2IUIA 1JYRA 1GRIA 1IJRA 2EO3A 1A81A 2DLYA 1M61A 5DF6A 1GHUA 1O4LA 3US4A 1A07A 4OHLA 5HKZA 2LNXA 4U1PA 3CXLA 3BKBA 1LUIA 2MQIA 1O4BA 2XP1A 3C7IA 2YU7A 2CRHA 3BUOB 2EYVA 1O4JA 5HKYA 4JGHA 1MILA 2RMXA 1KC2A 2L4KA 3IMDA 2HDVA 3ZNIA 2HCKA 1R1SA 1I3ZA 1XA6A 2HDXA 2MC1A 3VS4A 4GWFA 5D0JA 3VS1A 1O4NA 1Y57A 3VRNA 2DLZA 3TKZA 1O49A 2PNAA 1O4IA 2C0OA 1TCEA 4EY0A 1D4TA 1A1BA 2GE9A 3MXCA 5BO4A 3PQZA 3VS0A 2YSXA 1CWEA 1BF5A 4F59A 4NWGA 3S8OA 2ECDA 1O4OA 1A1CA 4A4CA 3VROA 3QWXX 1IS0A 1O4CA 4E68A 3PFVA 4QSYA 2BBUA 2RSYA 2C0IA 4TZIA 1H9OA 1JWOA 3CD3A 3VRPA 3TL0A 4M4ZA 1X27A 2FO0A 1O45A 1CSYA 4GPLB 1A1AA 5IBSA 3PSJA 2RORA 1F2FA 1WQUA 1FHSA 1PICA 1O43A 1AOUF 2PLDA 3K2TA 1AYDA 3VS3A 2EL8A 1K9AA 1QG1E 2EO6A 3CBLA 1SHDA 5CDWA 1BG1A 4FL3A 1JYUA 3BUMB 3MXYA 2EOBA 2IUGA 3HCKA 5DC9A 3VS5A 5GJIA 5EHRA 1O42A 2IUHA 1QADA 3UYOA 1BKLA 4OHDA 4OHIA 2KNOA 4L1BB 4H1OA 2FCIA 2DX0A 1LUKA 1Z3KA 1M27A 1QCFA 3VGOA 1LCKA 3OP0A 5AULA 1D4WA 1FBZA 2LRAA 3VS2A 1O48A 2DM0A 4F5AA 1BHHA 2DCRA 2AUGA 4OHHA 2CI8A 1KA6A 2PTKA 3VRYA 1B47A 3OB1B 1YVLA 5EELA 1O4FA 1O47A 2LCTA 4A4BA 3BUNB 3NHNA 3KFJA 3PS5A 1O46A 4OHEA 1CJ1A 1SPRA 1O4EA 1AD5A 4U17A 1BFIA 3QWYA 2EKXA 2MRJA 3GXXA 5I6VA 4DGXA 1AB2A 1AYBA 2QMSA 2KGYA 2C9WA 2L6KA 4K44A 1CWDL 3HHMB 1G83A 3PLFB 2B3OA 2SRCA 2AOBA 4LUEA 2PNBA 1BLJA 4H34A 5AXIA 2LQNA 5EEQA 3EACA 3IN8A 3WA4A 1O44A 4K45A 3VRZA 4F5BA 1NZVA 1P13A 2DVJA 1FU6A 1RPYA 2HUWA 1LUNA 1BM2A 4D8KA 2CR4A 3K2MA 4P9VA 2OZOA 3S9KA 1FU5A 3OV1A 1R1PA 2CS0A 3S8LA 3BUWB 1KA7A 4NWFA 2RVFA 1BKMA 5DC4A 5DC0B 2JYQA 3N84A 4K2RA 3IN7A 1AOTF 1LCJA 5KAZA 4EIHA 1BHFA 1RQQC 3MAZA 3GQIB 5HKWA 3VRQA 5IBMA 1UUSA 1O4DA 1SPSA 2LQWA 1SHBA 1HCSB 3OVEA 1UURA 1OPLA 1O4PA 4FBNA 1A1EA 2EYYA 1NZLA 1O4KA 2L3TA 1BHHB 1OO3A 1TZEE 2IZVA 1NRVA 2MRKA 1LKKA 1LKLA 1A08A 2KK6A 2SHPA 1SKJA 2K7AB 1F1WA 1X6CA 3PJPA 1O41A 1X0NA 4DGPA 1BFJA 2Y1MA 1O4RA 2CBLA 4XZ0A 2ETZA 2LNWA 1R1QA 3S8NA 1CSZA 1FBVA 1AYAA 1MW4A 2AOAA 1OPKA 5GJHA 4XZ1A 4ROJA 4GL9E 4P9ZA 1SHAA 2H8HA 3LYVA 1JU5A 2C0TA 1BMBA 2VIFA 4X6SA 3HIZB 5EHPA 1YVHA 3UF4A 2EYZA 1Y1UA 3EAZA 1OO4A 4JE4A 2EU0A 3T04A 1KSWA 1O4MA 2CIAA 3VRRA 3BUXB
chains in the Genus database with same CATH topology
3IMJA 2OQ1A 4FL2A 1A09A 4E93A 4LUDA 3M7FA 2Y1NA 2MK2A 2K79B 1BLKA 1O4GA 1D1ZA 1FYRA 5EG3B 3GXWA 1O4AA 1ZFPE 4WWQA 4K11A 1FMKA 3OB2B 1O4HA 3PSKA 1JYQA 3N8MA 2HMHA 2PLEA 1O4QA 1LUMA 1AYCA 1HCTB 3CWGA 1RJAA 4JEGA 2Y3AB 3VS7A 3N7YA 3VS6A 2H5KA 2ABLA 2GSBA 5J3XA 2CI9A 2H46E 2IUIA 1JYRA 1GRIA 1IJRA 2EO3A 1A81A 2DLYA 1M61A 5DF6A 1GHUA 1O4LA 3US4A 1A07A 4OHLA 5HKZA 2LNXA 4U1PA 3CXLA 3BKBA 1LUIA 2MQIA 1O4BA 2XP1A 3C7IA 2YU7A 2CRHA 3BUOB 2EYVA 1O4JA 5HKYA 1MILA 4JGHA 2RMXA 1KC2A 2L4KA 3IMDA 2HDVA 3ZNIA 2HCKA 1R1SA 1I3ZA 1XA6A 2HDXA 2MC1A 3VS4A 4GWFA 5D0JA 3VS1A 1O4NA 1Y57A 3VRNA 2DLZA 3TKZA 1O49A 2PNAA 1O4IA 2C0OA 1TCEA 4EY0A 1D4TA 1A1BA 2GE9A 3MXCA 5BO4A 3PQZA 3VS0A 2YSXA 1CWEA 1BF5A 4F59A 4NWGA 3S8OA 2ECDA 1O4OA 1A1CA 4A4CA 3VROA 3QWXX 1IS0A 1O4CA 4E68A 3PFVA 4QSYA 2BBUA 2RSYA 2C0IA 4TZIA 1H9OA 1JWOA 3CD3A 3VRPA 3TL0A 4M4ZA 1X27A 2FO0A 1O45A 1CSYA 4GPLB 1A1AA 5IBSA 3PSJA 2RORA 1F2FA 1WQUA 1FHSA 1PICA 1O43A 1AOUF 2PLDA 1AYDA 3VS3A 2EL8A 1K9AA 1QG1E 2EO6A 3CBLA 1SHDA 5CDWA 1BG1A 4FL3A 1JYUA 3BUMB 3MXYA 2EOBA 2IUGA 3HCKA 5DC9A 3VS5A 5GJIA 5EHRA 1O42A 2IUHA 1QADA 3UYOA 1BKLA 4OHDA 4OHIA 2KNOA 4L1BB 4H1OA 2FCIA 2DX0A 1LUKA 1Z3KA 1M27A 1QCFA 3VGOA 1LCKA 3OP0A 5AULA 1D4WA 1FBZA 3VS2A 1O48A 2DM0A 4F5AA 1BHHA 2DCRA 2AUGA 4OHHA 2CI8A 1KA6A 2PTKA 3VRYA 1B47A 3OB1B 1YVLA 5EELA 1O4FA 1O47A 2LCTA 4A4BA 3BUNB 3NHNA 3KFJA 3PS5A 1O46A 4OHEA 1CJ1A 1SPRA 1O4EA 1AD5A 4U17A 1BFIA 3QWYA 2EKXA 2MRJA 3GXXA 5I6VA 4DGXA 1AB2A 1AYBA 2QMSA 2C9WA 2L6KA 4K44A 1CWDL 3HHMB 1G83A 3PLFB 2B3OA 2SRCA 2AOBA 4LUEA 2PNBA 1BLJA 4H34A 5AXIA 2LQNA 5EEQA 3EACA 3IN8A 3WA4A 1O44A 4K45A 3VRZA 4F5BA 1NZVA 1P13A 2DVJA 1FU6A 1RPYA 2HUWA 1LUNA 1BM2A 4D8KA 2CR4A 3K2MA 4P9VA 2OZOA 3S9KA 1FU5A 3OV1A 1R1PA 2CS0A 3S8LA 3BUWB 1KA7A 4NWFA 5DC4A 1BKMA 2RVFA 5DC0B 2JYQA 3N84A 4K2RA 3IN7A 1AOTF 1LCJA 5KAZA 4EIHA 1BHFA 1RQQC 3MAZA 3GQIB 5HKWA 3VRQA 5IBMA 1UUSA 1O4DA 1SPSA 2LQWA 1SHBA 1HCSB 3OVEA 1UURA 1OPLA 1O4PA 4FBNA 1A1EA 2EYYA 1NZLA 1O4KA 2L3TA 1BHHB 1OO3A 1TZEE 2IZVA 1NRVA 2MRKA 1LKKA 1LKLA 1A08A 2KK6A 2SHPA 1SKJA 2K7AB 1F1WA 1X6CA 3PJPA 1O41A 1X0NA 4DGPA 1BFJA 2Y1MA 1O4RA 2CBLA 4XZ0A 2ETZA 2LNWA 1R1QA 3S8NA 1CSZA 1FBVA 1AYAA 1MW4A 2AOAA 1OPKA 5GJHA 4XZ1A 4ROJA 4GL9E 4P9ZA 1SHAA 2H8HA 1JU5A 2C0TA 1BMBA 2VIFA 4X6SA 3HIZB 5EHPA 1YVHA 3UF4A 2EYZA 1Y1UA 3EAZA 1OO4A 4JE4A 2EU0A 3T04A 1KSWA 1O4MA 2CIAA 3VRRA 3BUXB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3IMJ A;  2OQ1 A;  4FL2 A;  1A09 A;  4E93 A;  4LUD A;  3M7F A;  2Y1N A;  2MK2 A;  2K79 B;  1BLK A;  1O4G A;  1D1Z A;  1FYR A;  5EG3 B;  3GXW A;  1O4A A;  1ZFP E;  4WWQ A;  4K11 A;  1FMK A;  3OB2 B;  1O4H A;  3PSK A;  1JYQ A;  3N8M A;  2HMH A;  2PLE A;  1O4Q A;  1LUM A;  1AYC A;  1HCT B;  3CWG A;  1RJA A;  4JEG A;  2Y3A B;  3VS7 A;  3N7Y A;  3VS6 A;  2H5K A;  2ABL A;  2GSB A;  5J3X A;  2CI9 A;  2H46 E;  2IUI A;  1JYR A;  1GRI A;  1IJR A;  2EO3 A;  1A81 A;  2DLY A;  1M61 A;  5DF6 A;  1GHU A;  1O4L A;  3US4 A;  1A07 A;  4OHL A;  5HKZ A;  2LNX A;  4U1P A;  3CXL A;  3BKB A;  1LUI A;  2MQI A;  1O4B A;  2XP1 A;  3C7I A;  2YU7 A;  2CRH A;  3BUO B;  2EYV A;  1O4J A;  5HKY A;  1MIL A;  4JGH A;  2RMX A;  1KC2 A;  2L4K A;  3IMD A;  2HDV A;  3ZNI A;  2HCK A;  1R1S A;  1I3Z A;  1XA6 A;  2HDX A;  2MC1 A;  3VS4 A;  4GWF A;  5D0J A;  3VS1 A;  1O4N A;  1Y57 A;  3VRN A;  2DLZ A;  3TKZ A;  1O49 A;  2PNA A;  1O4I A;  2C0O A;  1TCE A;  4EY0 A;  1D4T A;  1A1B A;  2GE9 A;  3MXC A;  5BO4 A;  3PQZ A;  3VS0 A;  2YSX A;  1CWE A;  1BF5 A;  4F59 A;  4NWG A;  3S8O A;  2ECD A;  1O4O A;  1A1C A;  4A4C A;  3VRO A;  3QWX X;  1IS0 A;  1O4C A;  4E68 A;  3PFV A;  4QSY A;  2BBU A;  2RSY A;  2C0I A;  4TZI A;  1H9O A;  1JWO A;  3CD3 A;  3VRP A;  3TL0 A;  4M4Z A;  1X27 A;  2FO0 A;  1O45 A;  1CSY A;  4GPL B;  1A1A A;  5IBS A;  3PSJ A;  2ROR A;  1F2F A;  1WQU A;  1FHS A;  1PIC A;  1O43 A;  1AOU F;  2PLD A;  1AYD A;  3VS3 A;  2EL8 A;  1K9A A;  1QG1 E;  2EO6 A;  3CBL A;  1SHD A;  5CDW A;  1BG1 A;  4FL3 A;  1JYU A;  3BUM B;  3MXY A;  2EOB A;  2IUG A;  3HCK A;  5DC9 A;  3VS5 A;  5GJI A;  5EHR A;  1O42 A;  2IUH A;  1QAD A;  3UYO A;  1BKL A;  4OHD A;  4OHI A;  2KNO A;  4L1B B;  4H1O A;  2FCI A;  2DX0 A;  1LUK A;  1Z3K A;  1M27 A;  1QCF A;  3VGO A;  1LCK A;  3OP0 A;  5AUL A;  1D4W A;  1FBZ A;  3VS2 A;  1O48 A;  2DM0 A;  4F5A A;  1BHH A;  2DCR A;  2AUG A;  4OHH A;  2CI8 A;  1KA6 A;  2PTK A;  3VRY A;  1B47 A;  3OB1 B;  1YVL A;  5EEL A;  1O4F A;  1O47 A;  2LCT A;  4A4B A;  3BUN B;  3NHN A;  3KFJ A;  3PS5 A;  1O46 A;  4OHE A;  1CJ1 A;  1SPR A;  1O4E A;  1AD5 A;  4U17 A;  1BFI A;  3QWY A;  2EKX A;  2MRJ A;  3GXX A;  5I6V A;  4DGX A;  1AB2 A;  1AYB A;  2QMS A;  2C9W A;  2L6K A;  4K44 A;  1CWD L;  3HHM B;  1G83 A;  3PLF B;  2B3O A;  2SRC A;  2AOB A;  4LUE A;  2PNB A;  1BLJ A;  4H34 A;  5AXI A;  2LQN A;  5EEQ A;  3EAC A;  3IN8 A;  3WA4 A;  1O44 A;  4K45 A;  3VRZ A;  4F5B A;  1NZV A;  1P13 A;  2DVJ A;  1FU6 A;  1RPY A;  2HUW A;  1LUN A;  1BM2 A;  4D8K A;  2CR4 A;  3K2M A;  4P9V A;  2OZO A;  3S9K A;  1FU5 A;  3OV1 A;  1R1P A;  2CS0 A;  3S8L A;  3BUW B;  1KA7 A;  4NWF A;  5DC4 A;  1BKM A;  2RVF A;  5DC0 B;  2JYQ A;  3N84 A;  4K2R A;  3IN7 A;  1AOT F;  1LCJ A;  5KAZ A;  4EIH A;  1BHF A;  1RQQ C;  3MAZ A;  3GQI B;  5HKW A;  3VRQ A;  5IBM A;  1UUS A;  1O4D A;  1SPS A;  2LQW A;  1SHB A;  1HCS B;  3OVE A;  1UUR A;  1OPL A;  1O4P A;  4FBN A;  1A1E A;  2EYY A;  1NZL A;  1O4K A;  2L3T A;  1BHH B;  1OO3 A;  1TZE E;  2IZV A;  1NRV A;  2MRK A;  1LKK A;  1LKL A;  1A08 A;  2KK6 A;  2SHP A;  1SKJ A;  2K7A B;  1F1W A;  1X6C A;  3PJP A;  1O41 A;  1X0N A;  4DGP A;  1BFJ A;  2Y1M A;  1O4R A;  2CBL A;  4XZ0 A;  2ETZ A;  2LNW A;  1R1Q A;  3S8N A;  1CSZ A;  1FBV A;  1AYA A;  1MW4 A;  2AOA A;  1OPK A;  5GJH A;  4XZ1 A;  4ROJ A;  4GL9 E;  4P9Z A;  1SHA A;  2H8H A;  1JU5 A;  2C0T A;  1BMB A;  2VIF A;  4X6S A;  3HIZ B;  5EHP A;  1YVH A;  3UF4 A;  2EYZ A;  1Y1U A;  3EAZ A;  1OO4 A;  4JE4 A;  2EU0 A;  3T04 A;  1KSW A;  1O4M A;  2CIA A;  3VRR A;  3BUX B; 
#chains in the Genus database with same CATH topology
 3IMJ A;  2OQ1 A;  4FL2 A;  1A09 A;  4E93 A;  4LUD A;  3M7F A;  2Y1N A;  2MK2 A;  2K79 B;  1BLK A;  1O4G A;  1D1Z A;  1FYR A;  5EG3 B;  3GXW A;  1O4A A;  1ZFP E;  4WWQ A;  4K11 A;  1FMK A;  3OB2 B;  1O4H A;  3PSK A;  1JYQ A;  3N8M A;  2HMH A;  2PLE A;  1O4Q A;  1LUM A;  1AYC A;  1HCT B;  3CWG A;  1RJA A;  4JEG A;  2Y3A B;  3VS7 A;  3N7Y A;  3VS6 A;  2H5K A;  2ABL A;  2GSB A;  5J3X A;  2CI9 A;  2H46 E;  2IUI A;  1JYR A;  1GRI A;  1IJR A;  2EO3 A;  1A81 A;  2DLY A;  1M61 A;  5DF6 A;  1GHU A;  1O4L A;  3US4 A;  1A07 A;  4OHL A;  5HKZ A;  2LNX A;  4U1P A;  3CXL A;  3BKB A;  1LUI A;  2MQI A;  1O4B A;  2XP1 A;  3C7I A;  2YU7 A;  2CRH A;  3BUO B;  2EYV A;  1O4J A;  5HKY A;  4JGH A;  1MIL A;  2RMX A;  1KC2 A;  2L4K A;  3IMD A;  2HDV A;  3ZNI A;  2HCK A;  1R1S A;  1I3Z A;  1XA6 A;  2HDX A;  2MC1 A;  3VS4 A;  4GWF A;  5D0J A;  3VS1 A;  1O4N A;  1Y57 A;  3VRN A;  2DLZ A;  3TKZ A;  1O49 A;  2PNA A;  1O4I A;  2C0O A;  1TCE A;  4EY0 A;  1D4T A;  1A1B A;  2GE9 A;  3MXC A;  5BO4 A;  3PQZ A;  3VS0 A;  2YSX A;  1CWE A;  1BF5 A;  4F59 A;  4NWG A;  3S8O A;  2ECD A;  1O4O A;  1A1C A;  4A4C A;  3VRO A;  3QWX X;  1IS0 A;  1O4C A;  4E68 A;  3PFV A;  4QSY A;  2BBU A;  2RSY A;  2C0I A;  4TZI A;  1H9O A;  1JWO A;  3CD3 A;  3VRP A;  3TL0 A;  4M4Z A;  1X27 A;  2FO0 A;  1O45 A;  1CSY A;  4GPL B;  1A1A A;  5IBS A;  3PSJ A;  2ROR A;  1F2F A;  1WQU A;  1FHS A;  1PIC A;  1O43 A;  1AOU F;  2PLD A;  3K2T A;  1AYD A;  3VS3 A;  2EL8 A;  1K9A A;  1QG1 E;  2EO6 A;  3CBL A;  1SHD A;  5CDW A;  1BG1 A;  4FL3 A;  1JYU A;  3BUM B;  3MXY A;  2EOB A;  2IUG A;  3HCK A;  5DC9 A;  3VS5 A;  5GJI A;  5EHR A;  1O42 A;  2IUH A;  1QAD A;  3UYO A;  1BKL A;  4OHD A;  4OHI A;  2KNO A;  4L1B B;  4H1O A;  2FCI A;  2DX0 A;  1LUK A;  1Z3K A;  1M27 A;  1QCF A;  3VGO A;  1LCK A;  3OP0 A;  5AUL A;  1D4W A;  1FBZ A;  2LRA A;  3VS2 A;  1O48 A;  2DM0 A;  4F5A A;  1BHH A;  2DCR A;  2AUG A;  4OHH A;  2CI8 A;  1KA6 A;  2PTK A;  3VRY A;  1B47 A;  3OB1 B;  1YVL A;  5EEL A;  1O4F A;  1O47 A;  2LCT A;  4A4B A;  3BUN B;  3NHN A;  3KFJ A;  3PS5 A;  1O46 A;  4OHE A;  1CJ1 A;  1SPR A;  1O4E A;  1AD5 A;  4U17 A;  1BFI A;  3QWY A;  2EKX A;  2MRJ A;  3GXX A;  5I6V A;  4DGX A;  1AB2 A;  1AYB A;  2QMS A;  2KGY A;  2C9W A;  2L6K A;  4K44 A;  1CWD L;  3HHM B;  1G83 A;  3PLF B;  2B3O A;  2SRC A;  2AOB A;  4LUE A;  2PNB A;  1BLJ A;  4H34 A;  5AXI A;  2LQN A;  5EEQ A;  3EAC A;  3IN8 A;  3WA4 A;  1O44 A;  4K45 A;  3VRZ A;  4F5B A;  1NZV A;  1P13 A;  2DVJ A;  1FU6 A;  1RPY A;  2HUW A;  1LUN A;  1BM2 A;  4D8K A;  2CR4 A;  3K2M A;  4P9V A;  2OZO A;  3S9K A;  1FU5 A;  3OV1 A;  1R1P A;  2CS0 A;  3S8L A;  3BUW B;  1KA7 A;  4NWF A;  2RVF A;  1BKM A;  5DC4 A;  5DC0 B;  2JYQ A;  3N84 A;  4K2R A;  3IN7 A;  1AOT F;  1LCJ A;  5KAZ A;  4EIH A;  1BHF A;  1RQQ C;  3MAZ A;  3GQI B;  5HKW A;  3VRQ A;  5IBM A;  1UUS A;  1O4D A;  1SPS A;  2LQW A;  1SHB A;  1HCS B;  3OVE A;  1UUR A;  1OPL A;  1O4P A;  4FBN A;  1A1E A;  2EYY A;  1NZL A;  1O4K A;  2L3T A;  1BHH B;  1OO3 A;  1TZE E;  2IZV A;  1NRV A;  2MRK A;  1LKK A;  1LKL A;  1A08 A;  2KK6 A;  2SHP A;  1SKJ A;  2K7A B;  1F1W A;  1X6C A;  3PJP A;  1O41 A;  1X0N A;  4DGP A;  1BFJ A;  2Y1M A;  1O4R A;  2CBL A;  4XZ0 A;  2ETZ A;  2LNW A;  1R1Q A;  3S8N A;  1CSZ A;  1FBV A;  1AYA A;  1MW4 A;  2AOA A;  1OPK A;  5GJH A;  4XZ1 A;  4ROJ A;  4GL9 E;  4P9Z A;  1SHA A;  2H8H A;  3LYV A;  1JU5 A;  2C0T A;  1BMB A;  2VIF A;  4X6S A;  3HIZ B;  5EHP A;  1YVH A;  3UF4 A;  2EYZ A;  1Y1U A;  3EAZ A;  1OO4 A;  4JE4 A;  2EU0 A;  3T04 A;  1KSW A;  1O4M A;  2CIA A;  3VRR A;  3BUX B; 
#chains in the Genus database with same CATH homology
 3IMJ A;  2OQ1 A;  4FL2 A;  1A09 A;  4E93 A;  4LUD A;  3M7F A;  2Y1N A;  2MK2 A;  2K79 B;  1BLK A;  1O4G A;  1D1Z A;  1FYR A;  5EG3 B;  3GXW A;  1O4A A;  1ZFP E;  4WWQ A;  4K11 A;  1FMK A;  3OB2 B;  1O4H A;  3PSK A;  1JYQ A;  3N8M A;  2HMH A;  2PLE A;  1O4Q A;  1LUM A;  1AYC A;  1HCT B;  3CWG A;  1RJA A;  4JEG A;  2Y3A B;  3VS7 A;  3N7Y A;  3VS6 A;  2H5K A;  2ABL A;  2GSB A;  5J3X A;  2CI9 A;  2H46 E;  2IUI A;  1JYR A;  1GRI A;  1IJR A;  2EO3 A;  1A81 A;  2DLY A;  1M61 A;  5DF6 A;  1GHU A;  1O4L A;  3US4 A;  1A07 A;  4OHL A;  5HKZ A;  2LNX A;  4U1P A;  3CXL A;  3BKB A;  1LUI A;  2MQI A;  1O4B A;  2XP1 A;  3C7I A;  2YU7 A;  2CRH A;  3BUO B;  2EYV A;  1O4J A;  5HKY A;  1MIL A;  4JGH A;  2RMX A;  1KC2 A;  2L4K A;  3IMD A;  2HDV A;  3ZNI A;  2HCK A;  1R1S A;  1I3Z A;  1XA6 A;  2HDX A;  2MC1 A;  3VS4 A;  4GWF A;  5D0J A;  3VS1 A;  1O4N A;  1Y57 A;  3VRN A;  2DLZ A;  3TKZ A;  1O49 A;  2PNA A;  1O4I A;  2C0O A;  1TCE A;  4EY0 A;  1D4T A;  1A1B A;  2GE9 A;  3MXC A;  5BO4 A;  3PQZ A;  3VS0 A;  2YSX A;  1CWE A;  1BF5 A;  4F59 A;  4NWG A;  3S8O A;  2ECD A;  1O4O A;  1A1C A;  4A4C A;  3VRO A;  3QWX X;  1IS0 A;  1O4C A;  4E68 A;  3PFV A;  4QSY A;  2BBU A;  2RSY A;  2C0I A;  4TZI A;  1H9O A;  1JWO A;  3CD3 A;  3VRP A;  3TL0 A;  4M4Z A;  1X27 A;  2FO0 A;  1O45 A;  1CSY A;  4GPL B;  1A1A A;  5IBS A;  3PSJ A;  2ROR A;  1F2F A;  1WQU A;  1FHS A;  1PIC A;  1O43 A;  1AOU F;  2PLD A;  1AYD A;  3VS3 A;  2EL8 A;  1K9A A;  1QG1 E;  2EO6 A;  3CBL A;  1SHD A;  5CDW A;  1BG1 A;  4FL3 A;  1JYU A;  3BUM B;  3MXY A;  2EOB A;  2IUG A;  3HCK A;  5DC9 A;  3VS5 A;  5GJI A;  5EHR A;  1O42 A;  2IUH A;  1QAD A;  3UYO A;  1BKL A;  4OHD A;  4OHI A;  2KNO A;  4L1B B;  4H1O A;  2FCI A;  2DX0 A;  1LUK A;  1Z3K A;  1M27 A;  1QCF A;  3VGO A;  1LCK A;  3OP0 A;  5AUL A;  1D4W A;  1FBZ A;  3VS2 A;  1O48 A;  2DM0 A;  4F5A A;  1BHH A;  2DCR A;  2AUG A;  4OHH A;  2CI8 A;  1KA6 A;  2PTK A;  3VRY A;  1B47 A;  3OB1 B;  1YVL A;  5EEL A;  1O4F A;  1O47 A;  2LCT A;  4A4B A;  3BUN B;  3NHN A;  3KFJ A;  3PS5 A;  1O46 A;  4OHE A;  1CJ1 A;  1SPR A;  1O4E A;  1AD5 A;  4U17 A;  1BFI A;  3QWY A;  2EKX A;  2MRJ A;  3GXX A;  5I6V A;  4DGX A;  1AB2 A;  1AYB A;  2QMS A;  2C9W A;  2L6K A;  4K44 A;  1CWD L;  3HHM B;  1G83 A;  3PLF B;  2B3O A;  2SRC A;  2AOB A;  4LUE A;  2PNB A;  1BLJ A;  4H34 A;  5AXI A;  2LQN A;  5EEQ A;  3EAC A;  3IN8 A;  3WA4 A;  1O44 A;  4K45 A;  3VRZ A;  4F5B A;  1NZV A;  1P13 A;  2DVJ A;  1FU6 A;  1RPY A;  2HUW A;  1LUN A;  1BM2 A;  4D8K A;  2CR4 A;  3K2M A;  4P9V A;  2OZO A;  3S9K A;  1FU5 A;  3OV1 A;  1R1P A;  2CS0 A;  3S8L A;  3BUW B;  1KA7 A;  4NWF A;  5DC4 A;  1BKM A;  2RVF A;  5DC0 B;  2JYQ A;  3N84 A;  4K2R A;  3IN7 A;  1AOT F;  1LCJ A;  5KAZ A;  4EIH A;  1BHF A;  1RQQ C;  3MAZ A;  3GQI B;  5HKW A;  3VRQ A;  5IBM A;  1UUS A;  1O4D A;  1SPS A;  2LQW A;  1SHB A;  1HCS B;  3OVE A;  1UUR A;  1OPL A;  1O4P A;  4FBN A;  1A1E A;  2EYY A;  1NZL A;  1O4K A;  2L3T A;  1BHH B;  1OO3 A;  1TZE E;  2IZV A;  1NRV A;  2MRK A;  1LKK A;  1LKL A;  1A08 A;  2KK6 A;  2SHP A;  1SKJ A;  2K7A B;  1F1W A;  1X6C A;  3PJP A;  1O41 A;  1X0N A;  4DGP A;  1BFJ A;  2Y1M A;  1O4R A;  2CBL A;  4XZ0 A;  2ETZ A;  2LNW A;  1R1Q A;  3S8N A;  1CSZ A;  1FBV A;  1AYA A;  1MW4 A;  2AOA A;  1OPK A;  5GJH A;  4XZ1 A;  4ROJ A;  4GL9 E;  4P9Z A;  1SHA A;  2H8H A;  1JU5 A;  2C0T A;  1BMB A;  2VIF A;  4X6S A;  3HIZ B;  5EHP A;  1YVH A;  3UF4 A;  2EYZ A;  1Y1U A;  3EAZ A;  1OO4 A;  4JE4 A;  2EU0 A;  3T04 A;  1KSW A;  1O4M A;  2CIA A;  3VRR A;  3BUX B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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