4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 7
molecule tags Signaling protein
source organism Homo sapiens
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
2KNOA 2CI8A 5J3XA 3IN7A 5AXIA 3PSKA 1H9OA 2MRJA 2L6KA 1O4OA 3EACA 4DGXA 5AULA 1GHUA 3VS5A 4FL2A 2FCIA 3VS2A 2YSXA 1QADA 3VRYA 3NHNA 5DC0B 1M61A 4GPLB 1UUSA 4JEGA 4DGPA 2DLZA 5I6VA 1D1ZA 3VS3A 2IUGA 1KC2A 1ZFPE 3TKZA 1O4FA 2EYVA 3MAZA 3M7FA 4F5AA 1O44A 3HHMB 2DVJA 4D8KA 2EO3A 3OB1B 3OV1A 1RQQC 1GRIA 2H46E 2Y1MA 5CDWA 1FBZA 1LUMA 1KA7A 4K45A 2L3TA 2XP1A 5IBMA 1OO3A 2ECDA 3MXCA 1WQUA 4NWGA 1LKKA 4OHHA 1JU5A 3VS6A 1HCTB 1D4WA 1LUIA 2CI9A 1O48A 4XZ1A 2OQ1A 3VRPA 1BG1A 3OB2B 4U17A 2KK6A 2GE9A 4OHLA 1I3ZA 2DM0A 2HDXA 3N8MA 3KFJA 1CWDL 1BHHB 1AYAA 2AOBA 3N84A 2C0TA 2CIAA 2QMSA 1O4KA 3GQIB 1O4PA 1AD5A 1O4QA 2RORA 3PLFB 2AOAA 1R1SA 1A1CA 4OHIA 1UURA 1AB2A 2FO0A 2LQWA 2HCKA 1R1QA 1KSWA 4A4BA 2H5KA 1O4DA 1FYRA 1BFJA 3IMDA 3BKBA 2CS0A 4H34A 1BMBA 4F5BA 1O4IA 3BUNB 5HKYA 1YVLA 4P9VA 3BUMB 4NWFA 1FU6A 1JWOA 3GXXA 2HDVA 5DF6A 2EU0A 4ROJA 1BHFA 3PQZA 5KAZA 3UYOA 3VRQA 1Z3KA 1A09A 1NRVA 1XA6A 1Y57A 1O4EA 5IBSA 3UF4A 3PFVA 2CRHA 2DLYA 3HIZB 4F59A 1HCSB 1A07A 1LCJA 2EOBA 1BHHA 1O47A 2C0OA 4JGHA 1SKJA 1A1EA 3T04A 3VRNA 3IMJA 3PS5A 1LKLA 1OPLA 1JYUA 2LNXA 2MK2A 1BKLA 1AOUF 2GSBA 3CWGA 2DX0A 2AUGA 3S8LA 1BKMA 1AYDA 1A1BA 3MXYA 1SPSA 3OVEA 1JYRA 2VIFA 2ABLA 3TL0A 5BO4A 5HKWA 4M4ZA 3PJPA 1O49A 1F2FA 1X0NA 1FU5A 4XZ0A 1M27A 2MC1A 4X6SA 1B47A 2EO6A 1O4BA 2RMXA 1QCFA 2PLDA 2DCRA 1X27A 3VS1A 2HMHA 3VS4A 1A1AA 2OZOA 3N7YA 5EHRA 1PICA 2EL8A 1BLJA 4GWFA 2HUWA 1BLKA 4FL3A 3VS7A 1O4CA 3C7IA 1A08A 1Y1UA 1NZVA 2B3OA 4U1PA 2RVFA 1NZLA 2MRKA 1O43A 2C9WA 2CR4A 2JYQA 4K11A 4E93A 1O4HA 4EY0A 2RSYA 2PNAA 2LQNA 1O41A 1RJAA 2EYYA 3HCKA 2K79B 4E68A 3S8NA 3CD3A 1QG1E 4TZIA 1CWEA 1KA6A 1O4AA 3VRRA 5EEQA 1LCKA 4QSYA 3ZNIA 1SHDA 3BUXB 4H1OA 1SHAA 2LNWA 2BBUA 3QWXX 5GJIA 3VGOA 2SHPA 3US4A 5DC9A 5GJHA 5EHPA 4EIHA 1AYCA 4K44A 3GXWA 4K2RA 2L4KA 4LUDA 4WWQA 1O46A 1O4RA 1F1WA 3CXLA 3S9KA 1YVHA 1MW4A 2Y3AB 1FHSA 2ETZA 1AYBA 4P9ZA 3WA4A 3PSJA 4GL9E 1SHBA 1K9AA 5D0JA 2SRCA 1IS0A 1O4MA 5HKZA 5EG3B 4JE4A 3K2MA 2IUIA 2H8HA 1BFIA 1O4JA 3EAZA 1IJRA 3VROA 2YU7A 1O42A 1RPYA 2IZVA 2PNBA 2PLEA 3CBLA 1G83A 2PTKA 3QWYA 1LUNA 3BUWB 3IN8A 1CSYA 4LUEA 1TZEE 1BM2A 2CBLA 1O4LA 1CSZA 2IUHA 1CJ1A 1OO4A 3OP0A 4A4CA 4FBNA 1FBVA 1P13A 1LUKA 1OPKA 2K7AB 1X6CA 1A81A 1AOTF 3VS0A 1O4NA 2EKXA 5DC4A 3S8OA 2Y1NA 1TCEA 1MILA 4L1BB 5EELA 1BF5A 4OHDA 1O45A 1SPRA 2MQIA 3BUOB 2EYZA 1D4TA 1O4GA 1JYQA 4OHEA 3VRZA 2LCTA 2C0IA 1FMKA 1R1PA
chains in the Genus database with same CATH superfamily
2KNOA 2CI8A 5J3XA 3IN7A 5AXIA 3PSKA 1H9OA 2MRJA 2L6KA 1O4OA 3EACA 4DGXA 5AULA 1GHUA 3VS5A 4FL2A 2FCIA 3VS2A 2YSXA 1QADA 3VRYA 3NHNA 5DC0B 1M61A 4GPLB 1UUSA 4JEGA 4DGPA 2DLZA 5I6VA 1D1ZA 3VS3A 2IUGA 1KC2A 1ZFPE 3TKZA 1O4FA 2EYVA 3MAZA 3M7FA 4F5AA 1O44A 3HHMB 2DVJA 4D8KA 2EO3A 3OB1B 3OV1A 1RQQC 1GRIA 2H46E 2Y1MA 5CDWA 1FBZA 1LUMA 1KA7A 4K45A 2L3TA 2XP1A 5IBMA 1OO3A 2ECDA 3MXCA 1WQUA 4NWGA 1LKKA 4OHHA 1JU5A 3VS6A 1HCTB 1D4WA 1LUIA 2CI9A 1O48A 4XZ1A 2OQ1A 3VRPA 1BG1A 3OB2B 4U17A 2KK6A 2GE9A 4OHLA 1I3ZA 2DM0A 2HDXA 3N8MA 3KFJA 1CWDL 1BHHB 1AYAA 2AOBA 3N84A 2C0TA 2CIAA 2QMSA 1O4KA 3GQIB 1O4PA 1AD5A 1O4QA 2RORA 3PLFB 2AOAA 1R1SA 1A1CA 4OHIA 1UURA 1AB2A 2FO0A 2LQWA 2HCKA 1R1QA 1KSWA 4A4BA 2H5KA 1O4DA 1FYRA 1BFJA 3IMDA 3BKBA 2CS0A 4H34A 1BMBA 4F5BA 1O4IA 3BUNB 5HKYA 1YVLA 4P9VA 3BUMB 4NWFA 1FU6A 1JWOA 3GXXA 2HDVA 5DF6A 2EU0A 4ROJA 1BHFA 3PQZA 5KAZA 3UYOA 3VRQA 1Z3KA 1A09A 1NRVA 1XA6A 1Y57A 1O4EA 5IBSA 3UF4A 3PFVA 2CRHA 2DLYA 3HIZB 4F59A 1HCSB 1A07A 1LCJA 2EOBA 1BHHA 1O47A 2C0OA 4JGHA 1SKJA 1A1EA 3T04A 3VRNA 3IMJA 3PS5A 1LKLA 1OPLA 1JYUA 2LNXA 2MK2A 1BKLA 1AOUF 2GSBA 3CWGA 2DX0A 2AUGA 3S8LA 1BKMA 1AYDA 1A1BA 3MXYA 1SPSA 3OVEA 1JYRA 2VIFA 2ABLA 2KGYA 3TL0A 5BO4A 5HKWA 4M4ZA 3PJPA 1O49A 1F2FA 1X0NA 1FU5A 4XZ0A 1M27A 2MC1A 4X6SA 1B47A 2EO6A 1O4BA 2RMXA 1QCFA 2PLDA 2DCRA 1X27A 3VS1A 2HMHA 3VS4A 1A1AA 2OZOA 3N7YA 5EHRA 1PICA 2EL8A 1BLJA 4GWFA 2HUWA 1BLKA 4FL3A 3VS7A 1O4CA 3C7IA 1A08A 1Y1UA 1NZVA 2B3OA 4U1PA 2RVFA 1NZLA 2MRKA 1O43A 2C9WA 2CR4A 2JYQA 4K11A 4E93A 1O4HA 4EY0A 2RSYA 2PNAA 2LQNA 1O41A 1RJAA 2EYYA 3HCKA 2K79B 4E68A 3S8NA 3CD3A 1QG1E 4TZIA 1CWEA 1KA6A 1O4AA 3VRRA 5EEQA 1LCKA 4QSYA 3ZNIA 1SHDA 3BUXB 4H1OA 1SHAA 2LNWA 2BBUA 3QWXX 5GJIA 3VGOA 2SHPA 3US4A 5DC9A 5GJHA 5EHPA 4EIHA 1AYCA 4K44A 3GXWA 4K2RA 2L4KA 4LUDA 4WWQA 1O46A 1O4RA 1F1WA 3CXLA 3S9KA 1YVHA 1MW4A 2Y3AB 1FHSA 2ETZA 1AYBA 4P9ZA 3WA4A 3PSJA 4GL9E 1SHBA 1K9AA 5D0JA 3LYVA 2SRCA 1IS0A 1O4MA 5HKZA 5EG3B 4JE4A 3K2MA 2IUIA 2H8HA 1BFIA 1O4JA 3EAZA 1IJRA 3VROA 2YU7A 1O42A 1RPYA 2IZVA 2PNBA 2PLEA 3CBLA 1G83A 2PTKA 3QWYA 1LUNA 3BUWB 3IN8A 1CSYA 4LUEA 1TZEE 1BM2A 2CBLA 1O4LA 1CSZA 2IUHA 1CJ1A 1OO4A 3OP0A 4A4CA 2LRAA 4FBNA 1FBVA 1P13A 1LUKA 1OPKA 3K2TA 2K7AB 1X6CA 1A81A 1AOTF 3VS0A 1O4NA 2EKXA 5DC4A 3S8OA 2Y1NA 1TCEA 1MILA 4L1BB 5EELA 1BF5A 4OHDA 1O45A 1SPRA 2MQIA 3BUOB 2EYZA 1D4TA 1O4GA 1JYQA 4OHEA 3VRZA 2LCTA 2C0IA 1FMKA 1R1PA
chains in the Genus database with same CATH topology
2KNOA 2CI8A 5J3XA 3IN7A 5AXIA 3PSKA 1H9OA 2MRJA 2L6KA 1O4OA 3EACA 4DGXA 5AULA 1GHUA 3VS5A 4FL2A 2FCIA 3VS2A 2YSXA 1QADA 3VRYA 3NHNA 5DC0B 1M61A 4GPLB 1UUSA 4JEGA 4DGPA 2DLZA 5I6VA 1D1ZA 3VS3A 2IUGA 1KC2A 1ZFPE 3TKZA 1O4FA 2EYVA 3MAZA 3M7FA 4F5AA 1O44A 3HHMB 2DVJA 4D8KA 2EO3A 3OB1B 3OV1A 1RQQC 1GRIA 2H46E 2Y1MA 5CDWA 1FBZA 1LUMA 1KA7A 4K45A 2L3TA 2XP1A 5IBMA 1OO3A 2ECDA 3MXCA 1WQUA 4NWGA 1LKKA 4OHHA 1JU5A 3VS6A 1HCTB 1D4WA 1LUIA 2CI9A 1O48A 4XZ1A 2OQ1A 3VRPA 1BG1A 3OB2B 4U17A 2KK6A 2GE9A 4OHLA 1I3ZA 2DM0A 2HDXA 3N8MA 3KFJA 1CWDL 1BHHB 1AYAA 2AOBA 3N84A 2C0TA 2CIAA 2QMSA 1O4KA 3GQIB 1O4PA 1AD5A 1O4QA 2RORA 3PLFB 2AOAA 1R1SA 1A1CA 4OHIA 1UURA 1AB2A 2FO0A 2LQWA 2HCKA 1R1QA 1KSWA 4A4BA 2H5KA 1O4DA 1FYRA 1BFJA 3IMDA 3BKBA 2CS0A 4H34A 1BMBA 4F5BA 1O4IA 3BUNB 5HKYA 1YVLA 4P9VA 3BUMB 4NWFA 1FU6A 1JWOA 3GXXA 2HDVA 5DF6A 2EU0A 4ROJA 1BHFA 3PQZA 5KAZA 3UYOA 3VRQA 1Z3KA 1A09A 1NRVA 1XA6A 1Y57A 1O4EA 5IBSA 3UF4A 3PFVA 2CRHA 2DLYA 3HIZB 4F59A 1HCSB 1A07A 1LCJA 2EOBA 1BHHA 1O47A 2C0OA 4JGHA 1SKJA 1A1EA 3T04A 3VRNA 3IMJA 3PS5A 1LKLA 1OPLA 1JYUA 2LNXA 2MK2A 1BKLA 1AOUF 2GSBA 3CWGA 2DX0A 2AUGA 3S8LA 1BKMA 1AYDA 1A1BA 3MXYA 1SPSA 3OVEA 1JYRA 2VIFA 2ABLA 3TL0A 5BO4A 5HKWA 4M4ZA 3PJPA 1O49A 1F2FA 1X0NA 1FU5A 4XZ0A 1M27A 2MC1A 4X6SA 1B47A 2EO6A 1O4BA 2RMXA 1QCFA 2PLDA 2DCRA 1X27A 3VS1A 2HMHA 3VS4A 1A1AA 2OZOA 3N7YA 5EHRA 1PICA 2EL8A 1BLJA 4GWFA 2HUWA 1BLKA 4FL3A 3VS7A 1O4CA 3C7IA 1A08A 1Y1UA 1NZVA 2B3OA 4U1PA 2RVFA 1NZLA 2MRKA 1O43A 2C9WA 2CR4A 2JYQA 4K11A 4E93A 1O4HA 4EY0A 2RSYA 2PNAA 2LQNA 1O41A 1RJAA 2EYYA 3HCKA 2K79B 4E68A 3S8NA 3CD3A 1QG1E 4TZIA 1CWEA 1KA6A 1O4AA 3VRRA 5EEQA 1LCKA 4QSYA 3ZNIA 1SHDA 3BUXB 4H1OA 1SHAA 2LNWA 2BBUA 3QWXX 5GJIA 3VGOA 2SHPA 3US4A 5DC9A 5GJHA 5EHPA 4EIHA 1AYCA 4K44A 3GXWA 4K2RA 2L4KA 4LUDA 4WWQA 1O46A 1O4RA 1F1WA 3CXLA 3S9KA 1YVHA 1MW4A 2Y3AB 1FHSA 2ETZA 1AYBA 4P9ZA 3WA4A 3PSJA 4GL9E 1SHBA 1K9AA 5D0JA 2SRCA 1IS0A 1O4MA 5HKZA 5EG3B 4JE4A 3K2MA 2IUIA 2H8HA 1BFIA 1O4JA 3EAZA 1IJRA 3VROA 2YU7A 1O42A 1RPYA 2IZVA 2PNBA 2PLEA 3CBLA 1G83A 2PTKA 3QWYA 1LUNA 3BUWB 3IN8A 1CSYA 4LUEA 1TZEE 1BM2A 2CBLA 1O4LA 1CSZA 2IUHA 1CJ1A 1OO4A 3OP0A 4A4CA 4FBNA 1FBVA 1P13A 1LUKA 1OPKA 2K7AB 1X6CA 1A81A 1AOTF 3VS0A 1O4NA 2EKXA 5DC4A 3S8OA 2Y1NA 1TCEA 1MILA 4L1BB 5EELA 1BF5A 4OHDA 1O45A 1SPRA 2MQIA 3BUOB 2EYZA 1D4TA 1O4GA 1JYQA 4OHEA 3VRZA 2LCTA 2C0IA 1FMKA 1R1PA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2KNO A;  2CI8 A;  5J3X A;  3IN7 A;  5AXI A;  3PSK A;  1H9O A;  2MRJ A;  2L6K A;  1O4O A;  3EAC A;  4DGX A;  5AUL A;  1GHU A;  3VS5 A;  4FL2 A;  2FCI A;  3VS2 A;  2YSX A;  1QAD A;  3VRY A;  3NHN A;  5DC0 B;  1M61 A;  4GPL B;  1UUS A;  4JEG A;  4DGP A;  2DLZ A;  5I6V A;  1D1Z A;  3VS3 A;  2IUG A;  1KC2 A;  1ZFP E;  3TKZ A;  1O4F A;  2EYV A;  3MAZ A;  3M7F A;  4F5A A;  1O44 A;  3HHM B;  2DVJ A;  4D8K A;  2EO3 A;  3OB1 B;  3OV1 A;  1RQQ C;  1GRI A;  2H46 E;  2Y1M A;  5CDW A;  1FBZ A;  1LUM A;  1KA7 A;  4K45 A;  2L3T A;  2XP1 A;  5IBM A;  1OO3 A;  2ECD A;  3MXC A;  1WQU A;  4NWG A;  1LKK A;  4OHH A;  1JU5 A;  3VS6 A;  1HCT B;  1D4W A;  1LUI A;  2CI9 A;  1O48 A;  4XZ1 A;  2OQ1 A;  3VRP A;  1BG1 A;  3OB2 B;  4U17 A;  2KK6 A;  2GE9 A;  4OHL A;  1I3Z A;  2DM0 A;  2HDX A;  3N8M A;  3KFJ A;  1CWD L;  1BHH B;  1AYA A;  2AOB A;  3N84 A;  2C0T A;  2CIA A;  2QMS A;  1O4K A;  3GQI B;  1O4P A;  1AD5 A;  1O4Q A;  2ROR A;  3PLF B;  2AOA A;  1R1S A;  1A1C A;  4OHI A;  1UUR A;  1AB2 A;  2FO0 A;  2LQW A;  2HCK A;  1R1Q A;  1KSW A;  4A4B A;  2H5K A;  1O4D A;  1FYR A;  1BFJ A;  3IMD A;  3BKB A;  2CS0 A;  4H34 A;  1BMB A;  4F5B A;  1O4I A;  3BUN B;  5HKY A;  1YVL A;  4P9V A;  3BUM B;  4NWF A;  1FU6 A;  1JWO A;  3GXX A;  2HDV A;  5DF6 A;  2EU0 A;  4ROJ A;  1BHF A;  3PQZ A;  5KAZ A;  3UYO A;  3VRQ A;  1Z3K A;  1A09 A;  1NRV A;  1XA6 A;  1Y57 A;  1O4E A;  5IBS A;  3UF4 A;  3PFV A;  2CRH A;  2DLY A;  3HIZ B;  4F59 A;  1HCS B;  1A07 A;  1LCJ A;  2EOB A;  1BHH A;  1O47 A;  2C0O A;  4JGH A;  1SKJ A;  1A1E A;  3T04 A;  3VRN A;  3IMJ A;  3PS5 A;  1LKL A;  1OPL A;  1JYU A;  2LNX A;  2MK2 A;  1BKL A;  1AOU F;  2GSB A;  3CWG A;  2DX0 A;  2AUG A;  3S8L A;  1BKM A;  1AYD A;  1A1B A;  3MXY A;  1SPS A;  3OVE A;  1JYR A;  2VIF A;  2ABL A;  3TL0 A;  5BO4 A;  5HKW A;  4M4Z A;  3PJP A;  1O49 A;  1F2F A;  1X0N A;  1FU5 A;  4XZ0 A;  1M27 A;  2MC1 A;  4X6S A;  1B47 A;  2EO6 A;  1O4B A;  2RMX A;  1QCF A;  2PLD A;  2DCR A;  1X27 A;  3VS1 A;  2HMH A;  3VS4 A;  1A1A A;  2OZO A;  3N7Y A;  5EHR A;  1PIC A;  2EL8 A;  1BLJ A;  4GWF A;  2HUW A;  1BLK A;  4FL3 A;  3VS7 A;  1O4C A;  3C7I A;  1A08 A;  1Y1U A;  1NZV A;  2B3O A;  4U1P A;  2RVF A;  1NZL A;  2MRK A;  1O43 A;  2C9W A;  2CR4 A;  2JYQ A;  4K11 A;  4E93 A;  1O4H A;  4EY0 A;  2RSY A;  2PNA A;  2LQN A;  1O41 A;  1RJA A;  2EYY A;  3HCK A;  2K79 B;  4E68 A;  3S8N A;  3CD3 A;  1QG1 E;  4TZI A;  1CWE A;  1KA6 A;  1O4A A;  3VRR A;  5EEQ A;  1LCK A;  4QSY A;  3ZNI A;  1SHD A;  3BUX B;  4H1O A;  1SHA A;  2LNW A;  2BBU A;  3QWX X;  5GJI A;  3VGO A;  2SHP A;  3US4 A;  5DC9 A;  5GJH A;  5EHP A;  4EIH A;  1AYC A;  4K44 A;  3GXW A;  4K2R A;  2L4K A;  4LUD A;  4WWQ A;  1O46 A;  1O4R A;  1F1W A;  3CXL A;  3S9K A;  1YVH A;  1MW4 A;  2Y3A B;  1FHS A;  2ETZ A;  1AYB A;  4P9Z A;  3WA4 A;  3PSJ A;  4GL9 E;  1SHB A;  1K9A A;  5D0J A;  2SRC A;  1IS0 A;  1O4M A;  5HKZ A;  5EG3 B;  4JE4 A;  3K2M A;  2IUI A;  2H8H A;  1BFI A;  1O4J A;  3EAZ A;  1IJR A;  3VRO A;  2YU7 A;  1O42 A;  1RPY A;  2IZV A;  2PNB A;  2PLE A;  3CBL A;  1G83 A;  2PTK A;  3QWY A;  1LUN A;  3BUW B;  3IN8 A;  1CSY A;  4LUE A;  1TZE E;  1BM2 A;  2CBL A;  1O4L A;  1CSZ A;  2IUH A;  1CJ1 A;  1OO4 A;  3OP0 A;  4A4C A;  4FBN A;  1FBV A;  1P13 A;  1LUK A;  1OPK A;  2K7A B;  1X6C A;  1A81 A;  1AOT F;  3VS0 A;  1O4N A;  2EKX A;  5DC4 A;  3S8O A;  2Y1N A;  1TCE A;  1MIL A;  4L1B B;  5EEL A;  1BF5 A;  4OHD A;  1O45 A;  1SPR A;  2MQI A;  3BUO B;  2EYZ A;  1D4T A;  1O4G A;  1JYQ A;  4OHE A;  3VRZ A;  2LCT A;  2C0I A;  1FMK A;  1R1P A; 
#chains in the Genus database with same CATH topology
 2KNO A;  2CI8 A;  5J3X A;  3IN7 A;  5AXI A;  3PSK A;  1H9O A;  2MRJ A;  2L6K A;  1O4O A;  3EAC A;  4DGX A;  5AUL A;  1GHU A;  3VS5 A;  4FL2 A;  2FCI A;  3VS2 A;  2YSX A;  1QAD A;  3VRY A;  3NHN A;  5DC0 B;  1M61 A;  4GPL B;  1UUS A;  4JEG A;  4DGP A;  2DLZ A;  5I6V A;  1D1Z A;  3VS3 A;  2IUG A;  1KC2 A;  1ZFP E;  3TKZ A;  1O4F A;  2EYV A;  3MAZ A;  3M7F A;  4F5A A;  1O44 A;  3HHM B;  2DVJ A;  4D8K A;  2EO3 A;  3OB1 B;  3OV1 A;  1RQQ C;  1GRI A;  2H46 E;  2Y1M A;  5CDW A;  1FBZ A;  1LUM A;  1KA7 A;  4K45 A;  2L3T A;  2XP1 A;  5IBM A;  1OO3 A;  2ECD A;  3MXC A;  1WQU A;  4NWG A;  1LKK A;  4OHH A;  1JU5 A;  3VS6 A;  1HCT B;  1D4W A;  1LUI A;  2CI9 A;  1O48 A;  4XZ1 A;  2OQ1 A;  3VRP A;  1BG1 A;  3OB2 B;  4U17 A;  2KK6 A;  2GE9 A;  4OHL A;  1I3Z A;  2DM0 A;  2HDX A;  3N8M A;  3KFJ A;  1CWD L;  1BHH B;  1AYA A;  2AOB A;  3N84 A;  2C0T A;  2CIA A;  2QMS A;  1O4K A;  3GQI B;  1O4P A;  1AD5 A;  1O4Q A;  2ROR A;  3PLF B;  2AOA A;  1R1S A;  1A1C A;  4OHI A;  1UUR A;  1AB2 A;  2FO0 A;  2LQW A;  2HCK A;  1R1Q A;  1KSW A;  4A4B A;  2H5K A;  1O4D A;  1FYR A;  1BFJ A;  3IMD A;  3BKB A;  2CS0 A;  4H34 A;  1BMB A;  4F5B A;  1O4I A;  3BUN B;  5HKY A;  1YVL A;  4P9V A;  3BUM B;  4NWF A;  1FU6 A;  1JWO A;  3GXX A;  2HDV A;  5DF6 A;  2EU0 A;  4ROJ A;  1BHF A;  3PQZ A;  5KAZ A;  3UYO A;  3VRQ A;  1Z3K A;  1A09 A;  1NRV A;  1XA6 A;  1Y57 A;  1O4E A;  5IBS A;  3UF4 A;  3PFV A;  2CRH A;  2DLY A;  3HIZ B;  4F59 A;  1HCS B;  1A07 A;  1LCJ A;  2EOB A;  1BHH A;  1O47 A;  2C0O A;  4JGH A;  1SKJ A;  1A1E A;  3T04 A;  3VRN A;  3IMJ A;  3PS5 A;  1LKL A;  1OPL A;  1JYU A;  2LNX A;  2MK2 A;  1BKL A;  1AOU F;  2GSB A;  3CWG A;  2DX0 A;  2AUG A;  3S8L A;  1BKM A;  1AYD A;  1A1B A;  3MXY A;  1SPS A;  3OVE A;  1JYR A;  2VIF A;  2ABL A;  2KGY A;  3TL0 A;  5BO4 A;  5HKW A;  4M4Z A;  3PJP A;  1O49 A;  1F2F A;  1X0N A;  1FU5 A;  4XZ0 A;  1M27 A;  2MC1 A;  4X6S A;  1B47 A;  2EO6 A;  1O4B A;  2RMX A;  1QCF A;  2PLD A;  2DCR A;  1X27 A;  3VS1 A;  2HMH A;  3VS4 A;  1A1A A;  2OZO A;  3N7Y A;  5EHR A;  1PIC A;  2EL8 A;  1BLJ A;  4GWF A;  2HUW A;  1BLK A;  4FL3 A;  3VS7 A;  1O4C A;  3C7I A;  1A08 A;  1Y1U A;  1NZV A;  2B3O A;  4U1P A;  2RVF A;  1NZL A;  2MRK A;  1O43 A;  2C9W A;  2CR4 A;  2JYQ A;  4K11 A;  4E93 A;  1O4H A;  4EY0 A;  2RSY A;  2PNA A;  2LQN A;  1O41 A;  1RJA A;  2EYY A;  3HCK A;  2K79 B;  4E68 A;  3S8N A;  3CD3 A;  1QG1 E;  4TZI A;  1CWE A;  1KA6 A;  1O4A A;  3VRR A;  5EEQ A;  1LCK A;  4QSY A;  3ZNI A;  1SHD A;  3BUX B;  4H1O A;  1SHA A;  2LNW A;  2BBU A;  3QWX X;  5GJI A;  3VGO A;  2SHP A;  3US4 A;  5DC9 A;  5GJH A;  5EHP A;  4EIH A;  1AYC A;  4K44 A;  3GXW A;  4K2R A;  2L4K A;  4LUD A;  4WWQ A;  1O46 A;  1O4R A;  1F1W A;  3CXL A;  3S9K A;  1YVH A;  1MW4 A;  2Y3A B;  1FHS A;  2ETZ A;  1AYB A;  4P9Z A;  3WA4 A;  3PSJ A;  4GL9 E;  1SHB A;  1K9A A;  5D0J A;  3LYV A;  2SRC A;  1IS0 A;  1O4M A;  5HKZ A;  5EG3 B;  4JE4 A;  3K2M A;  2IUI A;  2H8H A;  1BFI A;  1O4J A;  3EAZ A;  1IJR A;  3VRO A;  2YU7 A;  1O42 A;  1RPY A;  2IZV A;  2PNB A;  2PLE A;  3CBL A;  1G83 A;  2PTK A;  3QWY A;  1LUN A;  3BUW B;  3IN8 A;  1CSY A;  4LUE A;  1TZE E;  1BM2 A;  2CBL A;  1O4L A;  1CSZ A;  2IUH A;  1CJ1 A;  1OO4 A;  3OP0 A;  4A4C A;  2LRA A;  4FBN A;  1FBV A;  1P13 A;  1LUK A;  1OPK A;  3K2T A;  2K7A B;  1X6C A;  1A81 A;  1AOT F;  3VS0 A;  1O4N A;  2EKX A;  5DC4 A;  3S8O A;  2Y1N A;  1TCE A;  1MIL A;  4L1B B;  5EEL A;  1BF5 A;  4OHD A;  1O45 A;  1SPR A;  2MQI A;  3BUO B;  2EYZ A;  1D4T A;  1O4G A;  1JYQ A;  4OHE A;  3VRZ A;  2LCT A;  2C0I A;  1FMK A;  1R1P A; 
#chains in the Genus database with same CATH homology
 2KNO A;  2CI8 A;  5J3X A;  3IN7 A;  5AXI A;  3PSK A;  1H9O A;  2MRJ A;  2L6K A;  1O4O A;  3EAC A;  4DGX A;  5AUL A;  1GHU A;  3VS5 A;  4FL2 A;  2FCI A;  3VS2 A;  2YSX A;  1QAD A;  3VRY A;  3NHN A;  5DC0 B;  1M61 A;  4GPL B;  1UUS A;  4JEG A;  4DGP A;  2DLZ A;  5I6V A;  1D1Z A;  3VS3 A;  2IUG A;  1KC2 A;  1ZFP E;  3TKZ A;  1O4F A;  2EYV A;  3MAZ A;  3M7F A;  4F5A A;  1O44 A;  3HHM B;  2DVJ A;  4D8K A;  2EO3 A;  3OB1 B;  3OV1 A;  1RQQ C;  1GRI A;  2H46 E;  2Y1M A;  5CDW A;  1FBZ A;  1LUM A;  1KA7 A;  4K45 A;  2L3T A;  2XP1 A;  5IBM A;  1OO3 A;  2ECD A;  3MXC A;  1WQU A;  4NWG A;  1LKK A;  4OHH A;  1JU5 A;  3VS6 A;  1HCT B;  1D4W A;  1LUI A;  2CI9 A;  1O48 A;  4XZ1 A;  2OQ1 A;  3VRP A;  1BG1 A;  3OB2 B;  4U17 A;  2KK6 A;  2GE9 A;  4OHL A;  1I3Z A;  2DM0 A;  2HDX A;  3N8M A;  3KFJ A;  1CWD L;  1BHH B;  1AYA A;  2AOB A;  3N84 A;  2C0T A;  2CIA A;  2QMS A;  1O4K A;  3GQI B;  1O4P A;  1AD5 A;  1O4Q A;  2ROR A;  3PLF B;  2AOA A;  1R1S A;  1A1C A;  4OHI A;  1UUR A;  1AB2 A;  2FO0 A;  2LQW A;  2HCK A;  1R1Q A;  1KSW A;  4A4B A;  2H5K A;  1O4D A;  1FYR A;  1BFJ A;  3IMD A;  3BKB A;  2CS0 A;  4H34 A;  1BMB A;  4F5B A;  1O4I A;  3BUN B;  5HKY A;  1YVL A;  4P9V A;  3BUM B;  4NWF A;  1FU6 A;  1JWO A;  3GXX A;  2HDV A;  5DF6 A;  2EU0 A;  4ROJ A;  1BHF A;  3PQZ A;  5KAZ A;  3UYO A;  3VRQ A;  1Z3K A;  1A09 A;  1NRV A;  1XA6 A;  1Y57 A;  1O4E A;  5IBS A;  3UF4 A;  3PFV A;  2CRH A;  2DLY A;  3HIZ B;  4F59 A;  1HCS B;  1A07 A;  1LCJ A;  2EOB A;  1BHH A;  1O47 A;  2C0O A;  4JGH A;  1SKJ A;  1A1E A;  3T04 A;  3VRN A;  3IMJ A;  3PS5 A;  1LKL A;  1OPL A;  1JYU A;  2LNX A;  2MK2 A;  1BKL A;  1AOU F;  2GSB A;  3CWG A;  2DX0 A;  2AUG A;  3S8L A;  1BKM A;  1AYD A;  1A1B A;  3MXY A;  1SPS A;  3OVE A;  1JYR A;  2VIF A;  2ABL A;  3TL0 A;  5BO4 A;  5HKW A;  4M4Z A;  3PJP A;  1O49 A;  1F2F A;  1X0N A;  1FU5 A;  4XZ0 A;  1M27 A;  2MC1 A;  4X6S A;  1B47 A;  2EO6 A;  1O4B A;  2RMX A;  1QCF A;  2PLD A;  2DCR A;  1X27 A;  3VS1 A;  2HMH A;  3VS4 A;  1A1A A;  2OZO A;  3N7Y A;  5EHR A;  1PIC A;  2EL8 A;  1BLJ A;  4GWF A;  2HUW A;  1BLK A;  4FL3 A;  3VS7 A;  1O4C A;  3C7I A;  1A08 A;  1Y1U A;  1NZV A;  2B3O A;  4U1P A;  2RVF A;  1NZL A;  2MRK A;  1O43 A;  2C9W A;  2CR4 A;  2JYQ A;  4K11 A;  4E93 A;  1O4H A;  4EY0 A;  2RSY A;  2PNA A;  2LQN A;  1O41 A;  1RJA A;  2EYY A;  3HCK A;  2K79 B;  4E68 A;  3S8N A;  3CD3 A;  1QG1 E;  4TZI A;  1CWE A;  1KA6 A;  1O4A A;  3VRR A;  5EEQ A;  1LCK A;  4QSY A;  3ZNI A;  1SHD A;  3BUX B;  4H1O A;  1SHA A;  2LNW A;  2BBU A;  3QWX X;  5GJI A;  3VGO A;  2SHP A;  3US4 A;  5DC9 A;  5GJH A;  5EHP A;  4EIH A;  1AYC A;  4K44 A;  3GXW A;  4K2R A;  2L4K A;  4LUD A;  4WWQ A;  1O46 A;  1O4R A;  1F1W A;  3CXL A;  3S9K A;  1YVH A;  1MW4 A;  2Y3A B;  1FHS A;  2ETZ A;  1AYB A;  4P9Z A;  3WA4 A;  3PSJ A;  4GL9 E;  1SHB A;  1K9A A;  5D0J A;  2SRC A;  1IS0 A;  1O4M A;  5HKZ A;  5EG3 B;  4JE4 A;  3K2M A;  2IUI A;  2H8H A;  1BFI A;  1O4J A;  3EAZ A;  1IJR A;  3VRO A;  2YU7 A;  1O42 A;  1RPY A;  2IZV A;  2PNB A;  2PLE A;  3CBL A;  1G83 A;  2PTK A;  3QWY A;  1LUN A;  3BUW B;  3IN8 A;  1CSY A;  4LUE A;  1TZE E;  1BM2 A;  2CBL A;  1O4L A;  1CSZ A;  2IUH A;  1CJ1 A;  1OO4 A;  3OP0 A;  4A4C A;  4FBN A;  1FBV A;  1P13 A;  1LUK A;  1OPK A;  2K7A B;  1X6C A;  1A81 A;  1AOT F;  3VS0 A;  1O4N A;  2EKX A;  5DC4 A;  3S8O A;  2Y1N A;  1TCE A;  1MIL A;  4L1B B;  5EEL A;  1BF5 A;  4OHD A;  1O45 A;  1SPR A;  2MQI A;  3BUO B;  2EYZ A;  1D4T A;  1O4G A;  1JYQ A;  4OHE A;  3VRZ A;  2LCT A;  2C0I A;  1FMK A;  1R1P A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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