4EY0A

Structure of tandem sh2 domains from plcgamma1
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
243
structure length
234
Chain Sequence
NEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDFGAFVEANPM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
total genus 54
structure length 234
sequence length 243
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2012-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4ey0A02
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4ey0A01
2SRCA 4FL2A 3BUXB 1MW4A 2GE9A 3VRYA 4OHDA 3TL0A 3N7YA 2HDXA 4K44A 1BHHA 4A4CA 2DLYA 3MAZA 4NWGA 2GSBA 1LUKA 3ZNIA 3VS1A 1O4EA 5D0JA 3UYOA 4JGHA 1BMBA 1BLKA 1BM2A 1SHDA 3CBLA 2AOBA 1HCSB 1FBZA 5DF6A 4H34A 4JE4A 1O4KA 1BHFA 3IMDA 2FO0A 1CSZA 1I3ZA 2H5KA 1PICA 1BFJA 3CWGA 2K79B 2AUGA 1RJAA 1BKLA 3PQZA 1LKKA 3N8MA 5EHRA 2PNBA 1OPKA 1JYQA 4OHHA 1O42A 1CWEA 3VRRA 2L4KA 2EOBA 1A1BA 4X6SA 2IZVA 1O4MA 2HMHA 1LCJA 5HKWA 2PLDA 4TZIA 2H46E 5EG3B 4WWQA 1D4TA 2EL8A 1SHAA 1IJRA 3VRPA 4K2RA 2PNAA 5AULA 1JYRA 5DC4A 4P9VA 1O44A 1R1SA 1LUIA 2OQ1A 2LQWA 5EEQA 2HUWA 4DGXA 1IS0A 2L3TA 5BO4A 4F5BA 2CS0A 3VS4A 4H1OA 1CWDL 4GWFA 2B3OA 3EACA 4D8KA 1QG1E 2LNXA 1O4OA 2EYZA 1A09A 1JWOA 2IUHA 2C9WA 1KC2A 2EO6A 3IMJA 1X0NA 3OVEA 1O45A 2L6KA 1FBVA 1Z3KA 4XZ1A 1SHBA 1BLJA 3OB1B 3BUNB 5DC0B 3WA4A 1R1QA 2DCRA 2EYVA 1H9OA 1BHHB 1OO4A 2C0TA 1NZLA 1LUMA 4A4BA 5HKYA 3IN8A 4GPLB 5CDWA 2MC1A 1UUSA 5I6VA 2CBLA 2MK2A 2VIFA 2RMXA 1O4RA 2ECDA 2Y1NA 2EO3A 3VROA 4LUEA 2Y1MA 2ETZA 1NZVA 5GJHA 1KA6A 1FU5A 4E93A 2CIAA 2Y3AB 1O49A 1QADA 1X6CA 5HKZA 1R1PA 2H8HA 1CSYA 1O4GA 3OB2B 3VRZA 3VRQA 4QSYA 1G83A 2C0OA 4JEGA 1SKJA 2C0IA 2IUGA 4L1BB 2ABLA 1K9AA 2RORA 3EAZA 1O46A 3OP0A 3VRNA 2MQIA 2EU0A 4DGPA 2KNOA 1Y1UA 1CJ1A 2IUIA 2EYYA 3BUMB 1A81A 1O4IA 2MRKA 4K45A 2DM0A 2YU7A 3KFJA 4XZ0A 1NRVA 2CI8A 1P13A 1O47A 1AOTF 1RPYA 4M4ZA 3M7FA 2PTKA 1O4NA 1A1AA 2KK6A 3HIZB 3S9KA 4GL9E 1AOUF 3NHNA 3BUOB 3VS6A 4FBNA 2RVFA 3S8OA 1FHSA 3S8LA 3TKZA 1WQUA 1X27A 1F2FA 2DVJA 5GJIA 1FU6A 1O4AA 1AB2A 4P9ZA 1O4DA 1SPRA 3HCKA 1MILA 1OO3A 1JU5A 1BKMA 5DC9A 1QCFA 1XA6A 2HCKA 4LUDA 4OHEA 1HCTB 1FYRA 4OHLA 3PSJA 2CR4A 3QWXX 3VS2A 3MXYA 1LKLA 2CI9A 5EHPA 3PFVA 5AXIA 4FL3A 3BKBA 1FMKA 1O43A 1O41A 2K7AB 1AYAA 4K11A 1KSWA 1D4WA 4E68A 3IN7A 1BG1A 3VGOA 1D1ZA 2EKXA 5EELA 1F1WA 3QWYA 3VS7A 1O4PA 2XP1A 3C7IA 1O4QA 3S8NA 1A1CA 2MRJA 2JYQA 1M61A 4F59A 1O4JA 2LQNA 4U1PA 1AYDA 2PLEA 3N84A 1RQQC 3BUWB 1OPLA 1O4HA 3GQIB 1Y57A 2FCIA 1BF5A 1B47A 1ZFPE 3VS0A 3PS5A 2DX0A 3US4A 1A07A 3CD3A 5J3XA 3CXLA 1O4CA 2YSXA 4NWFA 1LUNA 1TCEA 2SHPA 2HDVA 2AOAA 4EY0A 2LCTA 1AYBA 1O48A 3VS3A 2OZOA 1UURA 4EIHA 5IBSA 3GXWA 2QMSA 5IBMA 1AYCA 4OHIA 3K2MA 1LCKA 1YVLA 4U17A 3UF4A 1BFIA 4ROJA 1O4LA 2LNWA 3PLFB 2CRHA 3PJPA 1JYUA 1M27A 4F5AA 1TZEE 1GRIA 3HHMB 1O4BA 3T04A 1A08A 2BBUA 1GHUA 3GXXA 3OV1A 1O4FA 3PSKA 2RSYA 3VS5A 1SPSA 1AD5A 3MXCA 5KAZA 1YVHA 2DLZA 1A1EA 1KA7A
chains in the Genus database with same CATH superfamily
2SRCA 4FL2A 3BUXB 1MW4A 2GE9A 3VRYA 4OHDA 3TL0A 3N7YA 2HDXA 4K44A 1BHHA 4A4CA 2DLYA 3MAZA 4NWGA 2GSBA 1LUKA 3ZNIA 3VS1A 1O4EA 5D0JA 3UYOA 4JGHA 1BMBA 1BLKA 1BM2A 1SHDA 3CBLA 2AOBA 1HCSB 1FBZA 5DF6A 4H34A 4JE4A 1O4KA 1BHFA 3IMDA 2FO0A 1CSZA 1I3ZA 2H5KA 1PICA 1BFJA 3CWGA 2K79B 2AUGA 1RJAA 1BKLA 3PQZA 1LKKA 3N8MA 5EHRA 2PNBA 1OPKA 1JYQA 4OHHA 1O42A 1CWEA 3VRRA 2L4KA 2EOBA 1A1BA 4X6SA 2IZVA 1O4MA 2HMHA 1LCJA 5HKWA 2PLDA 4TZIA 2H46E 5EG3B 4WWQA 1D4TA 2EL8A 1SHAA 1IJRA 3VRPA 4K2RA 2PNAA 5AULA 1JYRA 5DC4A 4P9VA 1O44A 1R1SA 1LUIA 2OQ1A 2LQWA 5EEQA 2HUWA 4DGXA 1IS0A 2L3TA 5BO4A 4F5BA 2CS0A 3VS4A 4H1OA 1CWDL 4GWFA 2B3OA 3EACA 4D8KA 1QG1E 2LNXA 1O4OA 2EYZA 1A09A 1JWOA 2IUHA 2C9WA 1KC2A 2EO6A 3IMJA 1X0NA 3OVEA 1O45A 2L6KA 1FBVA 1Z3KA 4XZ1A 1SHBA 1BLJA 3OB1B 3BUNB 5DC0B 3WA4A 1R1QA 2DCRA 2EYVA 3K2TA 1H9OA 1BHHB 1OO4A 2C0TA 1NZLA 1LUMA 4A4BA 5HKYA 3IN8A 4GPLB 5CDWA 2MC1A 1UUSA 5I6VA 2CBLA 2MK2A 2VIFA 2RMXA 1O4RA 2ECDA 2Y1NA 2EO3A 3VROA 4LUEA 2Y1MA 2ETZA 1NZVA 5GJHA 1KA6A 1FU5A 4E93A 2CIAA 2Y3AB 1O49A 1QADA 1X6CA 5HKZA 1R1PA 2H8HA 1CSYA 1O4GA 3OB2B 3VRZA 3VRQA 4QSYA 1G83A 2C0OA 4JEGA 1SKJA 2C0IA 2IUGA 4L1BB 2ABLA 1K9AA 2RORA 3EAZA 1O46A 3OP0A 3VRNA 2MQIA 2EU0A 4DGPA 2KNOA 1Y1UA 1CJ1A 2IUIA 2EYYA 3BUMB 1A81A 1O4IA 2MRKA 4K45A 2DM0A 2YU7A 3KFJA 4XZ0A 1NRVA 2CI8A 1P13A 1O47A 1AOTF 1RPYA 4M4ZA 3M7FA 2PTKA 1O4NA 1A1AA 2KK6A 3HIZB 3S9KA 4GL9E 1AOUF 3NHNA 3BUOB 3VS6A 4FBNA 2RVFA 3S8OA 1FHSA 3S8LA 3TKZA 1WQUA 1X27A 1F2FA 2DVJA 5GJIA 1FU6A 1O4AA 1AB2A 4P9ZA 1O4DA 1SPRA 3HCKA 1MILA 1OO3A 1JU5A 1BKMA 5DC9A 1QCFA 1XA6A 2HCKA 4LUDA 4OHEA 1HCTB 1FYRA 4OHLA 3LYVA 3PSJA 2CR4A 3QWXX 3VS2A 3MXYA 1LKLA 2CI9A 5EHPA 3PFVA 5AXIA 4FL3A 3BKBA 1FMKA 1O43A 1O41A 2K7AB 1AYAA 4K11A 1KSWA 1D4WA 4E68A 3IN7A 1BG1A 3VGOA 1D1ZA 2EKXA 5EELA 1F1WA 3QWYA 3VS7A 1O4PA 2XP1A 3C7IA 1O4QA 3S8NA 1A1CA 2MRJA 2JYQA 1M61A 4F59A 1O4JA 2LQNA 4U1PA 1AYDA 2PLEA 3N84A 1RQQC 3BUWB 1OPLA 1O4HA 3GQIB 1Y57A 2FCIA 1BF5A 1B47A 1ZFPE 3VS0A 3PS5A 2DX0A 3US4A 1A07A 3CD3A 5J3XA 3CXLA 1O4CA 2YSXA 4NWFA 1LUNA 1TCEA 2SHPA 2HDVA 2AOAA 4EY0A 2LCTA 1AYBA 1O48A 3VS3A 2OZOA 1UURA 4EIHA 5IBSA 3GXWA 2QMSA 5IBMA 1AYCA 4OHIA 3K2MA 1LCKA 1YVLA 4U17A 3UF4A 1BFIA 4ROJA 1O4LA 2LNWA 3PLFB 2CRHA 3PJPA 1JYUA 1M27A 2LRAA 4F5AA 1TZEE 1GRIA 2KGYA 3HHMB 1O4BA 3T04A 1A08A 2BBUA 1GHUA 3GXXA 3OV1A 1O4FA 3PSKA 2RSYA 3VS5A 1SPSA 1AD5A 3MXCA 5KAZA 1YVHA 2DLZA 1A1EA 1KA7A
chains in the Genus database with same CATH topology
2SRCA 4FL2A 3BUXB 1MW4A 2GE9A 3VRYA 4OHDA 3TL0A 3N7YA 2HDXA 4K44A 1BHHA 4A4CA 2DLYA 3MAZA 4NWGA 2GSBA 1LUKA 3ZNIA 3VS1A 1O4EA 5D0JA 3UYOA 4JGHA 1BMBA 1BLKA 1BM2A 1SHDA 3CBLA 2AOBA 1HCSB 1FBZA 5DF6A 4H34A 4JE4A 1O4KA 1BHFA 3IMDA 2FO0A 1CSZA 1I3ZA 2H5KA 1PICA 1BFJA 3CWGA 2K79B 2AUGA 1RJAA 1BKLA 3PQZA 1LKKA 3N8MA 5EHRA 2PNBA 1OPKA 1JYQA 4OHHA 1O42A 1CWEA 3VRRA 2L4KA 2EOBA 1A1BA 4X6SA 2IZVA 1O4MA 2HMHA 1LCJA 5HKWA 2PLDA 4TZIA 2H46E 5EG3B 4WWQA 1D4TA 2EL8A 1SHAA 1IJRA 3VRPA 4K2RA 2PNAA 5AULA 1JYRA 5DC4A 4P9VA 1O44A 1R1SA 1LUIA 2OQ1A 2LQWA 5EEQA 2HUWA 4DGXA 1IS0A 2L3TA 5BO4A 4F5BA 2CS0A 3VS4A 4H1OA 1CWDL 4GWFA 2B3OA 3EACA 4D8KA 1QG1E 2LNXA 1O4OA 2EYZA 1A09A 1JWOA 2IUHA 2C9WA 1KC2A 2EO6A 3IMJA 1X0NA 3OVEA 1O45A 2L6KA 1FBVA 1Z3KA 4XZ1A 1SHBA 1BLJA 3OB1B 3BUNB 5DC0B 3WA4A 1R1QA 2DCRA 2EYVA 1H9OA 1BHHB 1OO4A 2C0TA 1NZLA 1LUMA 4A4BA 5HKYA 3IN8A 4GPLB 5CDWA 2MC1A 1UUSA 5I6VA 2CBLA 2MK2A 2VIFA 2RMXA 1O4RA 2ECDA 2Y1NA 2EO3A 3VROA 4LUEA 2Y1MA 2ETZA 1NZVA 5GJHA 1KA6A 1FU5A 4E93A 2CIAA 2Y3AB 1O49A 1QADA 1X6CA 5HKZA 1R1PA 2H8HA 1CSYA 1O4GA 3OB2B 3VRZA 3VRQA 4QSYA 1G83A 2C0OA 4JEGA 1SKJA 2C0IA 2IUGA 4L1BB 2ABLA 1K9AA 2RORA 3EAZA 1O46A 3OP0A 3VRNA 2MQIA 2EU0A 4DGPA 2KNOA 1Y1UA 1CJ1A 2IUIA 2EYYA 3BUMB 1A81A 1O4IA 2MRKA 4K45A 2DM0A 2YU7A 3KFJA 4XZ0A 1NRVA 2CI8A 1P13A 1O47A 1AOTF 1RPYA 4M4ZA 3M7FA 2PTKA 1O4NA 1A1AA 2KK6A 3HIZB 3S9KA 4GL9E 1AOUF 3NHNA 3BUOB 3VS6A 4FBNA 2RVFA 3S8OA 1FHSA 3S8LA 3TKZA 1WQUA 1X27A 1F2FA 2DVJA 5GJIA 1FU6A 1O4AA 1AB2A 4P9ZA 1O4DA 1SPRA 3HCKA 1MILA 1OO3A 1JU5A 1BKMA 5DC9A 1QCFA 1XA6A 2HCKA 4LUDA 4OHEA 1HCTB 1FYRA 4OHLA 3PSJA 2CR4A 3QWXX 3VS2A 3MXYA 1LKLA 2CI9A 5EHPA 3PFVA 5AXIA 4FL3A 3BKBA 1FMKA 1O43A 1O41A 2K7AB 1AYAA 4K11A 1KSWA 1D4WA 4E68A 3IN7A 1BG1A 3VGOA 1D1ZA 2EKXA 5EELA 1F1WA 3QWYA 3VS7A 1O4PA 2XP1A 3C7IA 1O4QA 3S8NA 1A1CA 2MRJA 2JYQA 1M61A 4F59A 1O4JA 2LQNA 4U1PA 1AYDA 2PLEA 3N84A 1RQQC 3BUWB 1OPLA 1O4HA 3GQIB 1Y57A 2FCIA 1BF5A 1B47A 1ZFPE 3VS0A 3PS5A 2DX0A 3US4A 1A07A 3CD3A 5J3XA 3CXLA 1O4CA 2YSXA 4NWFA 1LUNA 1TCEA 2SHPA 2HDVA 2AOAA 4EY0A 2LCTA 1AYBA 1O48A 3VS3A 2OZOA 1UURA 4EIHA 5IBSA 3GXWA 2QMSA 5IBMA 1AYCA 4OHIA 3K2MA 1LCKA 1YVLA 4U17A 3UF4A 1BFIA 4ROJA 1O4LA 2LNWA 3PLFB 2CRHA 3PJPA 1JYUA 1M27A 4F5AA 1TZEE 1GRIA 3HHMB 1O4BA 3T04A 1A08A 2BBUA 1GHUA 3GXXA 3OV1A 1O4FA 3PSKA 2RSYA 3VS5A 1SPSA 1AD5A 3MXCA 5KAZA 1YVHA 2DLZA 1A1EA 1KA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SRC A;  4FL2 A;  3BUX B;  1MW4 A;  2GE9 A;  3VRY A;  4OHD A;  3TL0 A;  3N7Y A;  2HDX A;  4K44 A;  1BHH A;  4A4C A;  2DLY A;  3MAZ A;  4NWG A;  2GSB A;  1LUK A;  3ZNI A;  3VS1 A;  1O4E A;  5D0J A;  3UYO A;  4JGH A;  1BMB A;  1BLK A;  1BM2 A;  1SHD A;  3CBL A;  2AOB A;  1HCS B;  1FBZ A;  5DF6 A;  4H34 A;  4JE4 A;  1O4K A;  1BHF A;  3IMD A;  2FO0 A;  1CSZ A;  1I3Z A;  2H5K A;  1PIC A;  1BFJ A;  3CWG A;  2K79 B;  2AUG A;  1RJA A;  1BKL A;  3PQZ A;  1LKK A;  3N8M A;  5EHR A;  2PNB A;  1OPK A;  1JYQ A;  4OHH A;  1O42 A;  1CWE A;  3VRR A;  2L4K A;  2EOB A;  1A1B A;  4X6S A;  2IZV A;  1O4M A;  2HMH A;  1LCJ A;  5HKW A;  2PLD A;  4TZI A;  2H46 E;  5EG3 B;  4WWQ A;  1D4T A;  2EL8 A;  1SHA A;  1IJR A;  3VRP A;  4K2R A;  2PNA A;  5AUL A;  1JYR A;  5DC4 A;  4P9V A;  1O44 A;  1R1S A;  1LUI A;  2OQ1 A;  2LQW A;  5EEQ A;  2HUW A;  4DGX A;  1IS0 A;  2L3T A;  5BO4 A;  4F5B A;  2CS0 A;  3VS4 A;  4H1O A;  1CWD L;  4GWF A;  2B3O A;  3EAC A;  4D8K A;  1QG1 E;  2LNX A;  1O4O A;  2EYZ A;  1A09 A;  1JWO A;  2IUH A;  2C9W A;  1KC2 A;  2EO6 A;  3IMJ A;  1X0N A;  3OVE A;  1O45 A;  2L6K A;  1FBV A;  1Z3K A;  4XZ1 A;  1SHB A;  1BLJ A;  3OB1 B;  3BUN B;  5DC0 B;  3WA4 A;  1R1Q A;  2DCR A;  2EYV A;  1H9O A;  1BHH B;  1OO4 A;  2C0T A;  1NZL A;  1LUM A;  4A4B A;  5HKY A;  3IN8 A;  4GPL B;  5CDW A;  2MC1 A;  1UUS A;  5I6V A;  2CBL A;  2MK2 A;  2VIF A;  2RMX A;  1O4R A;  2ECD A;  2Y1N A;  2EO3 A;  3VRO A;  4LUE A;  2Y1M A;  2ETZ A;  1NZV A;  5GJH A;  1KA6 A;  1FU5 A;  4E93 A;  2CIA A;  2Y3A B;  1O49 A;  1QAD A;  1X6C A;  5HKZ A;  1R1P A;  2H8H A;  1CSY A;  1O4G A;  3OB2 B;  3VRZ A;  3VRQ A;  4QSY A;  1G83 A;  2C0O A;  4JEG A;  1SKJ A;  2C0I A;  2IUG A;  4L1B B;  2ABL A;  1K9A A;  2ROR A;  3EAZ A;  1O46 A;  3OP0 A;  3VRN A;  2MQI A;  2EU0 A;  4DGP A;  2KNO A;  1Y1U A;  1CJ1 A;  2IUI A;  2EYY A;  3BUM B;  1A81 A;  1O4I A;  2MRK A;  4K45 A;  2DM0 A;  2YU7 A;  3KFJ A;  4XZ0 A;  1NRV A;  2CI8 A;  1P13 A;  1O47 A;  1AOT F;  1RPY A;  4M4Z A;  3M7F A;  2PTK A;  1O4N A;  1A1A A;  2KK6 A;  3HIZ B;  3S9K A;  4GL9 E;  1AOU F;  3NHN A;  3BUO B;  3VS6 A;  4FBN A;  2RVF A;  3S8O A;  1FHS A;  3S8L A;  3TKZ A;  1WQU A;  1X27 A;  1F2F A;  2DVJ A;  5GJI A;  1FU6 A;  1O4A A;  1AB2 A;  4P9Z A;  1O4D A;  1SPR A;  3HCK A;  1MIL A;  1OO3 A;  1JU5 A;  1BKM A;  5DC9 A;  1QCF A;  1XA6 A;  2HCK A;  4LUD A;  4OHE A;  1HCT B;  1FYR A;  4OHL A;  3PSJ A;  2CR4 A;  3QWX X;  3VS2 A;  3MXY A;  1LKL A;  2CI9 A;  5EHP A;  3PFV A;  5AXI A;  4FL3 A;  3BKB A;  1FMK A;  1O43 A;  1O41 A;  2K7A B;  1AYA A;  4K11 A;  1KSW A;  1D4W A;  4E68 A;  3IN7 A;  1BG1 A;  3VGO A;  1D1Z A;  2EKX A;  5EEL A;  1F1W A;  3QWY A;  3VS7 A;  1O4P A;  2XP1 A;  3C7I A;  1O4Q A;  3S8N A;  1A1C A;  2MRJ A;  2JYQ A;  1M61 A;  4F59 A;  1O4J A;  2LQN A;  4U1P A;  1AYD A;  2PLE A;  3N84 A;  1RQQ C;  3BUW B;  1OPL A;  1O4H A;  3GQI B;  1Y57 A;  2FCI A;  1BF5 A;  1B47 A;  1ZFP E;  3VS0 A;  3PS5 A;  2DX0 A;  3US4 A;  1A07 A;  3CD3 A;  5J3X A;  3CXL A;  1O4C A;  2YSX A;  4NWF A;  1LUN A;  1TCE A;  2SHP A;  2HDV A;  2AOA A;  4EY0 A;  2LCT A;  1AYB A;  1O48 A;  3VS3 A;  2OZO A;  1UUR A;  4EIH A;  5IBS A;  3GXW A;  2QMS A;  5IBM A;  1AYC A;  4OHI A;  3K2M A;  1LCK A;  1YVL A;  4U17 A;  3UF4 A;  1BFI A;  4ROJ A;  1O4L A;  2LNW A;  3PLF B;  2CRH A;  3PJP A;  1JYU A;  1M27 A;  4F5A A;  1TZE E;  1GRI A;  3HHM B;  1O4B A;  3T04 A;  1A08 A;  2BBU A;  1GHU A;  3GXX A;  3OV1 A;  1O4F A;  3PSK A;  2RSY A;  3VS5 A;  1SPS A;  1AD5 A;  3MXC A;  5KAZ A;  1YVH A;  2DLZ A;  1A1E A;  1KA7 A; 
#chains in the Genus database with same CATH topology
 2SRC A;  4FL2 A;  3BUX B;  1MW4 A;  2GE9 A;  3VRY A;  4OHD A;  3TL0 A;  3N7Y A;  2HDX A;  4K44 A;  1BHH A;  4A4C A;  2DLY A;  3MAZ A;  4NWG A;  2GSB A;  1LUK A;  3ZNI A;  3VS1 A;  1O4E A;  5D0J A;  3UYO A;  4JGH A;  1BMB A;  1BLK A;  1BM2 A;  1SHD A;  3CBL A;  2AOB A;  1HCS B;  1FBZ A;  5DF6 A;  4H34 A;  4JE4 A;  1O4K A;  1BHF A;  3IMD A;  2FO0 A;  1CSZ A;  1I3Z A;  2H5K A;  1PIC A;  1BFJ A;  3CWG A;  2K79 B;  2AUG A;  1RJA A;  1BKL A;  3PQZ A;  1LKK A;  3N8M A;  5EHR A;  2PNB A;  1OPK A;  1JYQ A;  4OHH A;  1O42 A;  1CWE A;  3VRR A;  2L4K A;  2EOB A;  1A1B A;  4X6S A;  2IZV A;  1O4M A;  2HMH A;  1LCJ A;  5HKW A;  2PLD A;  4TZI A;  2H46 E;  5EG3 B;  4WWQ A;  1D4T A;  2EL8 A;  1SHA A;  1IJR A;  3VRP A;  4K2R A;  2PNA A;  5AUL A;  1JYR A;  5DC4 A;  4P9V A;  1O44 A;  1R1S A;  1LUI A;  2OQ1 A;  2LQW A;  5EEQ A;  2HUW A;  4DGX A;  1IS0 A;  2L3T A;  5BO4 A;  4F5B A;  2CS0 A;  3VS4 A;  4H1O A;  1CWD L;  4GWF A;  2B3O A;  3EAC A;  4D8K A;  1QG1 E;  2LNX A;  1O4O A;  2EYZ A;  1A09 A;  1JWO A;  2IUH A;  2C9W A;  1KC2 A;  2EO6 A;  3IMJ A;  1X0N A;  3OVE A;  1O45 A;  2L6K A;  1FBV A;  1Z3K A;  4XZ1 A;  1SHB A;  1BLJ A;  3OB1 B;  3BUN B;  5DC0 B;  3WA4 A;  1R1Q A;  2DCR A;  2EYV A;  3K2T A;  1H9O A;  1BHH B;  1OO4 A;  2C0T A;  1NZL A;  1LUM A;  4A4B A;  5HKY A;  3IN8 A;  4GPL B;  5CDW A;  2MC1 A;  1UUS A;  5I6V A;  2CBL A;  2MK2 A;  2VIF A;  2RMX A;  1O4R A;  2ECD A;  2Y1N A;  2EO3 A;  3VRO A;  4LUE A;  2Y1M A;  2ETZ A;  1NZV A;  5GJH A;  1KA6 A;  1FU5 A;  4E93 A;  2CIA A;  2Y3A B;  1O49 A;  1QAD A;  1X6C A;  5HKZ A;  1R1P A;  2H8H A;  1CSY A;  1O4G A;  3OB2 B;  3VRZ A;  3VRQ A;  4QSY A;  1G83 A;  2C0O A;  4JEG A;  1SKJ A;  2C0I A;  2IUG A;  4L1B B;  2ABL A;  1K9A A;  2ROR A;  3EAZ A;  1O46 A;  3OP0 A;  3VRN A;  2MQI A;  2EU0 A;  4DGP A;  2KNO A;  1Y1U A;  1CJ1 A;  2IUI A;  2EYY A;  3BUM B;  1A81 A;  1O4I A;  2MRK A;  4K45 A;  2DM0 A;  2YU7 A;  3KFJ A;  4XZ0 A;  1NRV A;  2CI8 A;  1P13 A;  1O47 A;  1AOT F;  1RPY A;  4M4Z A;  3M7F A;  2PTK A;  1O4N A;  1A1A A;  2KK6 A;  3HIZ B;  3S9K A;  4GL9 E;  1AOU F;  3NHN A;  3BUO B;  3VS6 A;  4FBN A;  2RVF A;  3S8O A;  1FHS A;  3S8L A;  3TKZ A;  1WQU A;  1X27 A;  1F2F A;  2DVJ A;  5GJI A;  1FU6 A;  1O4A A;  1AB2 A;  4P9Z A;  1O4D A;  1SPR A;  3HCK A;  1MIL A;  1OO3 A;  1JU5 A;  1BKM A;  5DC9 A;  1QCF A;  1XA6 A;  2HCK A;  4LUD A;  4OHE A;  1HCT B;  1FYR A;  4OHL A;  3LYV A;  3PSJ A;  2CR4 A;  3QWX X;  3VS2 A;  3MXY A;  1LKL A;  2CI9 A;  5EHP A;  3PFV A;  5AXI A;  4FL3 A;  3BKB A;  1FMK A;  1O43 A;  1O41 A;  2K7A B;  1AYA A;  4K11 A;  1KSW A;  1D4W A;  4E68 A;  3IN7 A;  1BG1 A;  3VGO A;  1D1Z A;  2EKX A;  5EEL A;  1F1W A;  3QWY A;  3VS7 A;  1O4P A;  2XP1 A;  3C7I A;  1O4Q A;  3S8N A;  1A1C A;  2MRJ A;  2JYQ A;  1M61 A;  4F59 A;  1O4J A;  2LQN A;  4U1P A;  1AYD A;  2PLE A;  3N84 A;  1RQQ C;  3BUW B;  1OPL A;  1O4H A;  3GQI B;  1Y57 A;  2FCI A;  1BF5 A;  1B47 A;  1ZFP E;  3VS0 A;  3PS5 A;  2DX0 A;  3US4 A;  1A07 A;  3CD3 A;  5J3X A;  3CXL A;  1O4C A;  2YSX A;  4NWF A;  1LUN A;  1TCE A;  2SHP A;  2HDV A;  2AOA A;  4EY0 A;  2LCT A;  1AYB A;  1O48 A;  3VS3 A;  2OZO A;  1UUR A;  4EIH A;  5IBS A;  3GXW A;  2QMS A;  5IBM A;  1AYC A;  4OHI A;  3K2M A;  1LCK A;  1YVL A;  4U17 A;  3UF4 A;  1BFI A;  4ROJ A;  1O4L A;  2LNW A;  3PLF B;  2CRH A;  3PJP A;  1JYU A;  1M27 A;  2LRA A;  4F5A A;  1TZE E;  1GRI A;  2KGY A;  3HHM B;  1O4B A;  3T04 A;  1A08 A;  2BBU A;  1GHU A;  3GXX A;  3OV1 A;  1O4F A;  3PSK A;  2RSY A;  3VS5 A;  1SPS A;  1AD5 A;  3MXC A;  5KAZ A;  1YVH A;  2DLZ A;  1A1E A;  1KA7 A; 
#chains in the Genus database with same CATH homology
 2SRC A;  4FL2 A;  3BUX B;  1MW4 A;  2GE9 A;  3VRY A;  4OHD A;  3TL0 A;  3N7Y A;  2HDX A;  4K44 A;  1BHH A;  4A4C A;  2DLY A;  3MAZ A;  4NWG A;  2GSB A;  1LUK A;  3ZNI A;  3VS1 A;  1O4E A;  5D0J A;  3UYO A;  4JGH A;  1BMB A;  1BLK A;  1BM2 A;  1SHD A;  3CBL A;  2AOB A;  1HCS B;  1FBZ A;  5DF6 A;  4H34 A;  4JE4 A;  1O4K A;  1BHF A;  3IMD A;  2FO0 A;  1CSZ A;  1I3Z A;  2H5K A;  1PIC A;  1BFJ A;  3CWG A;  2K79 B;  2AUG A;  1RJA A;  1BKL A;  3PQZ A;  1LKK A;  3N8M A;  5EHR A;  2PNB A;  1OPK A;  1JYQ A;  4OHH A;  1O42 A;  1CWE A;  3VRR A;  2L4K A;  2EOB A;  1A1B A;  4X6S A;  2IZV A;  1O4M A;  2HMH A;  1LCJ A;  5HKW A;  2PLD A;  4TZI A;  2H46 E;  5EG3 B;  4WWQ A;  1D4T A;  2EL8 A;  1SHA A;  1IJR A;  3VRP A;  4K2R A;  2PNA A;  5AUL A;  1JYR A;  5DC4 A;  4P9V A;  1O44 A;  1R1S A;  1LUI A;  2OQ1 A;  2LQW A;  5EEQ A;  2HUW A;  4DGX A;  1IS0 A;  2L3T A;  5BO4 A;  4F5B A;  2CS0 A;  3VS4 A;  4H1O A;  1CWD L;  4GWF A;  2B3O A;  3EAC A;  4D8K A;  1QG1 E;  2LNX A;  1O4O A;  2EYZ A;  1A09 A;  1JWO A;  2IUH A;  2C9W A;  1KC2 A;  2EO6 A;  3IMJ A;  1X0N A;  3OVE A;  1O45 A;  2L6K A;  1FBV A;  1Z3K A;  4XZ1 A;  1SHB A;  1BLJ A;  3OB1 B;  3BUN B;  5DC0 B;  3WA4 A;  1R1Q A;  2DCR A;  2EYV A;  1H9O A;  1BHH B;  1OO4 A;  2C0T A;  1NZL A;  1LUM A;  4A4B A;  5HKY A;  3IN8 A;  4GPL B;  5CDW A;  2MC1 A;  1UUS A;  5I6V A;  2CBL A;  2MK2 A;  2VIF A;  2RMX A;  1O4R A;  2ECD A;  2Y1N A;  2EO3 A;  3VRO A;  4LUE A;  2Y1M A;  2ETZ A;  1NZV A;  5GJH A;  1KA6 A;  1FU5 A;  4E93 A;  2CIA A;  2Y3A B;  1O49 A;  1QAD A;  1X6C A;  5HKZ A;  1R1P A;  2H8H A;  1CSY A;  1O4G A;  3OB2 B;  3VRZ A;  3VRQ A;  4QSY A;  1G83 A;  2C0O A;  4JEG A;  1SKJ A;  2C0I A;  2IUG A;  4L1B B;  2ABL A;  1K9A A;  2ROR A;  3EAZ A;  1O46 A;  3OP0 A;  3VRN A;  2MQI A;  2EU0 A;  4DGP A;  2KNO A;  1Y1U A;  1CJ1 A;  2IUI A;  2EYY A;  3BUM B;  1A81 A;  1O4I A;  2MRK A;  4K45 A;  2DM0 A;  2YU7 A;  3KFJ A;  4XZ0 A;  1NRV A;  2CI8 A;  1P13 A;  1O47 A;  1AOT F;  1RPY A;  4M4Z A;  3M7F A;  2PTK A;  1O4N A;  1A1A A;  2KK6 A;  3HIZ B;  3S9K A;  4GL9 E;  1AOU F;  3NHN A;  3BUO B;  3VS6 A;  4FBN A;  2RVF A;  3S8O A;  1FHS A;  3S8L A;  3TKZ A;  1WQU A;  1X27 A;  1F2F A;  2DVJ A;  5GJI A;  1FU6 A;  1O4A A;  1AB2 A;  4P9Z A;  1O4D A;  1SPR A;  3HCK A;  1MIL A;  1OO3 A;  1JU5 A;  1BKM A;  5DC9 A;  1QCF A;  1XA6 A;  2HCK A;  4LUD A;  4OHE A;  1HCT B;  1FYR A;  4OHL A;  3PSJ A;  2CR4 A;  3QWX X;  3VS2 A;  3MXY A;  1LKL A;  2CI9 A;  5EHP A;  3PFV A;  5AXI A;  4FL3 A;  3BKB A;  1FMK A;  1O43 A;  1O41 A;  2K7A B;  1AYA A;  4K11 A;  1KSW A;  1D4W A;  4E68 A;  3IN7 A;  1BG1 A;  3VGO A;  1D1Z A;  2EKX A;  5EEL A;  1F1W A;  3QWY A;  3VS7 A;  1O4P A;  2XP1 A;  3C7I A;  1O4Q A;  3S8N A;  1A1C A;  2MRJ A;  2JYQ A;  1M61 A;  4F59 A;  1O4J A;  2LQN A;  4U1P A;  1AYD A;  2PLE A;  3N84 A;  1RQQ C;  3BUW B;  1OPL A;  1O4H A;  3GQI B;  1Y57 A;  2FCI A;  1BF5 A;  1B47 A;  1ZFP E;  3VS0 A;  3PS5 A;  2DX0 A;  3US4 A;  1A07 A;  3CD3 A;  5J3X A;  3CXL A;  1O4C A;  2YSX A;  4NWF A;  1LUN A;  1TCE A;  2SHP A;  2HDV A;  2AOA A;  4EY0 A;  2LCT A;  1AYB A;  1O48 A;  3VS3 A;  2OZO A;  1UUR A;  4EIH A;  5IBS A;  3GXW A;  2QMS A;  5IBM A;  1AYC A;  4OHI A;  3K2M A;  1LCK A;  1YVL A;  4U17 A;  3UF4 A;  1BFI A;  4ROJ A;  1O4L A;  2LNW A;  3PLF B;  2CRH A;  3PJP A;  1JYU A;  1M27 A;  4F5A A;  1TZE E;  1GRI A;  3HHM B;  1O4B A;  3T04 A;  1A08 A;  2BBU A;  1GHU A;  3GXX A;  3OV1 A;  1O4F A;  3PSK A;  2RSY A;  3VS5 A;  1SPS A;  1AD5 A;  3MXC A;  5KAZ A;  1YVH A;  2DLZ A;  1A1E A;  1KA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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